keyword
MENU ▼
Read by QxMD icon Read
search

Limbic lobe

keyword
https://www.readbyqxmd.com/read/29781194/paraneoplastic-autoimmune-encephalitis-associated-with-pleomorphic-lung-carcinoma-an-autopsy-case-report
#1
Takashi Ando, Yoji Goto, Kazuo Mano, Fumio Nomura, Masako Kurashige, Masafumi Ito, Maya Mimuro, Yasushi Iwasaki, Masahisa Katsuno, Mari Yoshida
A 64-year-old man was admitted with acute onset disturbed consciousness. Cerebrospinal fluid analysis revealed pleocytosis and elevated protein, with negative cultures and PCR. Serum antibodies for autoimmune encephalitis were also negative. Brain magnetic resonance imaging (MRI) was unremarkable, but whole-body CT scan showed a tumor in the left lower lung lobe. Bronchial brush cytology demonstrated clusters of malignant cells, and 18 F-fluorodeoxyglucose positron emission tomography showed multiple lesions and increased uptake in the lung tumor...
May 20, 2018: Neuropathology: Official Journal of the Japanese Society of Neuropathology
https://www.readbyqxmd.com/read/29743581/evolution-of-gamma-knife-capsulotomy-for-intractable-obsessive-compulsive-disorder
#2
REVIEW
Euripedes C Miguel, Antonio C Lopes, Nicole C R McLaughlin, Georg Norén, André F Gentil, Clement Hamani, Roseli G Shavitt, Marcelo C Batistuzzo, Edoardo F Q Vattimo, Miguel Canteras, Antonio De Salles, Alessandra Gorgulho, João Victor Salvajoli, Erich Talamoni Fonoff, Ian Paddick, Marcelo Q Hoexter, Christer Lindquist, Suzanne N Haber, Benjamin D Greenberg, Sameer A Sheth
For more than half a century, stereotactic neurosurgical procedures have been available to treat patients with severe, debilitating symptoms of obsessive-compulsive disorder (OCD) that have proven refractory to extensive, appropriate pharmacological, and psychological treatment. Although reliable predictors of outcome remain elusive, the establishment of narrower selection criteria for neurosurgical candidacy, together with a better understanding of the functional neuroanatomy implicated in OCD, has resulted in improved clinical efficacy for an array of ablative and non-ablative intervention techniques targeting the cingulum, internal capsule, and other limbic regions...
May 9, 2018: Molecular Psychiatry
https://www.readbyqxmd.com/read/29742610/18f-fdg-pet-ct-in-anti-nmda-receptor-encephalitis-typical-pattern-and-follow-up
#3
Abdenasser Moubtakir, Sébastien Dejust, François Godard, Leila Messaoud, David Morland
We report the case of a 28-year-old woman presenting behavior disorders of subacute onset. She was referred in our institution for a suspicion of limbic encephalitis. F-FDG PET/CT did not show any mesiotemporal abnormality but depicted a decreased uptake of bilateral parietal and occipital lobes. This atypical pattern was compatible with an anti-N-methyl-D-aspartate receptor encephalitis that was later confirmed.
April 30, 2018: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/29740216/altered-functional-connectivity-density-in-patients-with-herpes-zoster-and-postherpetic-neuralgia
#4
Shunda Hong, Lili Gu, Fuqing Zhou, Jiaqi Liu, Muhua Huang, Jian Jiang, Laichang He, Honghan Gong, Xianjun Zeng
Purpose: The aim of this study was to explore intrinsic functional connectivity patterns in patients with herpes zoster (HZ) and postherpetic neuralgia (PHN). Patients and methods: Thirty-three right-handed HZ patients (13 males; mean age 57.15±9.30 years), 22 right-handed PHN patients (9 males; mean age 66.13±6.77 years), and 28 well-matched healthy controls (HC) (9 males; mean age 54.21±7.72 years) underwent resting-state functional magnetic resonance imaging for intrinsic functional connectivity analyses...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29717522/brain-morphologic-changes-in-early-stages-of-psychosis-implications-for-clinical-application-and-early-intervention
#5
Tsutomu Takahashi, Michio Suzuki
To date, a large number of magnetic resonance imaging (MRI) studies have been conducted in schizophrenia, which generally demonstrate gray matter reduction predominantly in the frontal and temporo-limbic regions, as well as gross brain abnormalities (e.g., a deviated sulcogyral pattern). Although the causes as well as timing and course of these findings remain elusive, these morphologic changes (especially gross brain abnormalities and medial temporal lobe atrophy) are likely present at illness onset, possibly reflecting early neurodevelopmental abnormalities...
May 1, 2018: Psychiatry and Clinical Neurosciences
https://www.readbyqxmd.com/read/29717222/paraneoplastic-limbic-encephalitis-associated-with-lung-cancer
#6
Kaini Shen, Yan Xu, Hongzhi Guan, Wei Zhong, Minjiang Chen, Jing Zhao, Longyun Li, Mengzhao Wang
Paraneoplastic limbic encephalitis (PLE) is a rare autoimmune neurological syndrome observed in lung cancer patients. We retrospectively investigated the clinical characteristics, treatment responses, and prognoses in 16 PLE patients who were subsequently diagnosed with lung cancer. Fifteen patients initially presented with disturbance of consciousness, 13 with disorientation, and 12 with seizures. Thirteen patients had autoantibodies, including eight with gamma aminobutyric acid B receptor (GABAB R) antibodies and eight with Hu antibodies...
May 1, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29707778/electroconvulsive-therapy-increases-brain-volume-in-major-depression-a-systematic-review-and-meta-analysis
#7
REVIEW
K Gbyl, P Videbech
OBJECTIVE: The main purpose of this review was to synthesise evidence on ECT's effects on brain's structure. METHOD: A systematic literature review of longitudinal studies of depressed patients treated with ECT using magnetic resonance imaging (MRI) and meta-analysis of ECT's effect on hippocampal volume. RESULTS: Thirty-two studies with 467 patients and 285 controls were included. The MRI studies did not find any evidence of ECT-related brain damage...
April 29, 2018: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29706150/neurosyphilis-mighty-imitator-forays-with-benign-presentation-and-unique-neuroimaging-findings
#8
Harmanpreet Tiwana, Aiesha Ahmed
Background: Common causes of temporal lobe hyper intensities are central nervous system infections like herpes simplex encephalitis, Lyme disease, limbic encephalitis and vascular pathology like Cerebral Autosomal Dominant Arteriopathy with Subcortical infarcts and Leukoencephalopathy. Methods: Personal assessment, laboratory data analysis and neuroimaging for the patient who was admitted to a central Pennsylvania tertiary care referral centre were conducted. Results: A 52-year-old male presented with a 1-year history of diffuse dysesthesia in upper and lower extremities with associated intermittent headaches and neck stiffness...
April 30, 2018: Sexual Health
https://www.readbyqxmd.com/read/29705713/the-neural-markers-of-mri-to-differentiate-depression-and-panic-disorder
#9
REVIEW
Chien-Han Lai
Depression and panic disorder (PD) share the common pathophysiology from the perspectives of neurotransmitters. The relatively high comorbidity between depression and PD contributes to the substantial obstacles to differentiate from depression and PD, especially for the brain pathophysiology. There are significant differences in the diagnostic criteria between depression and PD. However, the paradox of similar pathophysiology and different diagnostic criteria in these two disorders were still the issues needing to be addressed...
April 26, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/29695292/a-biomarker-study-in-long-lasting-amnestic-mild-cognitive-impairment
#10
Chiara Cerami, Alessandra Dodich, Sandro Iannaccone, Giuseppe Magnani, Roberto Santangelo, Luca Presotto, Alessandra Marcone, Luigi Gianolli, Stefano F Cappa, Daniela Perani
BACKGROUND: Mild cognitive impairment (MCI) is a heterogeneous syndrome resulting from Alzheimer's disease (AD) as well as to non-AD and non-neurodegenerative conditions. A subset of patients with amnestic MCI (aMCI) present with an unusually long-lasting course, a slow rate of clinical neuropsychological progression, and evidence of focal involvement of medial temporal lobe structures. In the present study, we explored positron emission tomography (PET) and cerebrospinal fluid (CSF) biomarkers in a sample of subjects with aMCI with such clinical features in order to provide in vivo evidence to improve disease characterisation in this subgroup...
April 25, 2018: Alzheimer's Research & Therapy
https://www.readbyqxmd.com/read/29665128/a-role-for-astrocyte-derived-amyloid-%C3%AE-peptides-in-the-degeneration-of-neurons-in-an-animal-model-of-temporal-lobe-epilepsy
#11
A Kodam, D Ourdev, M Maulik, J Hariharakrishnan, M Banerjee, Y Wang, S Kar
Kainic acid, an analogue of the excitatory neurotransmitter glutamate, can trigger seizures and neurotoxicity in the hippocampus and other limbic structures in a manner that mirrors the neuropathology of human temporal lobe epilepsy (TLE). However, the underlying mechanisms associated with the neurotoxicity remain unclear. Since amyloid-β (Aβ) peptides, which are critical in the development of Alzheimer's disease, can mediate toxicity by activating glutamatergic NMDA receptors, it is likely that the enhanced glutamatergic transmission that renders hippocampal neurons vulnerable to kainic acid treatment may involve Aβ peptides...
April 17, 2018: Brain Pathology
https://www.readbyqxmd.com/read/29575277/association-study-of-functional-polymorphisms-of-dopaminergic-pathway-in-epilepsy-related-factors-of-temporal-lobe-epilepsy-in-brazilian-population
#12
Juliana A Alcantara, Silvia Vincentiisa, Daniel S Kerr, Bernardo Dos Santos, Ruda Alessi, Helio van der Linden, Tiffany Chaim, Maurício H Serpa, Geraldo Busatto, Wagner F Gattaz, Renata Demarque, Kette Dr Valente
BACKGROUND: There is scarce data about the role of neurotransmission modulated by dopamine (DA) in epilepsy, especially temporal lobe epilepsy. This is the first study that aimed to analyze the dopaminergic polymorphisms in an etiologically homogeneous group of patients with temporal lobe epilepsy determined by hippocampal sclerosis (TLE-HS). Selected polymorphisms were: (i) the most expressed receptors in the limbic system D2-like (DRD2/ANKK1 TAQ-1A, D4_VNTR, and D4_rs1800955); (ii) the dopamine transporter DAT - 3 'untranslated region (3'UTR) and Intron 8; (iii) two degrading enzymes regulating the synaptic activity - the main metabolizer of dopamine Catechol-O-methyltransferase (COMT) and monoamine oxidase A (MAOA)...
March 25, 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29570898/novel-connectivity-map-normalization-procedure-for-improved-quantitative-investigation-of-structural-thalamic-connectivity-in-temporal-lobe-epilepsy-patients
#13
Brendan G Santyr, Jonathan C Lau, Seyed M Mirsattari, Jorge G Burneo, Sandrine de Ribaupierre, David A Steven, Andrew G Parrent, Keith MacDougall, Ali R Khan
BACKGROUND: Connectivity studies targeting the thalamus have revealed patterns of atrophy and deafferentiation in temporal lobe epilepsy (TLE). The thalamus can be parcellated using probabilistic tractography to demonstrate regions of cortical connectivity; however, sensitivity to smaller or less connected regions is low. PURPOSE/HYPOTHESIS: To investigate thalamic structural connectivity in a wider range of cortical and limbic structures in TLE patients using a novel connectivity map normalization procedure...
March 23, 2018: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29547157/structural-correlates-of-mild-cognitive-impairment-a-clinicovolumetric-study
#14
R Sheelakumari, C Kesavadas, V S Lekha, Sunitha Justus, P Sankara Sarma, Ramshekhar Menon
Context: Annually 10-12% of patients with mild cognitive impairment (MCI) are likely to progress to Alzheimer's Disease (AD). The morphometric profile in stable non-converters has not been adequately characterized. Aims: To determine the structural differences between amnestic MCI and early AD using volumetric magnetic resonance imaging (MRI) and its correlation with neuropsychological test performances. Settings and Design: This was a hospital-based case-control study...
March 2018: Neurology India
https://www.readbyqxmd.com/read/29519459/pain-syndromes-and-the-parietal-lobe
#15
Luis Garcia-Larrea, François Mauguière
Pain was considered to be integrated subcortically during most of the 20th century, and it was not until 1956 that focal injury to the parietal opercular-insular cortex was shown to produce selective loss of pain senses. The parietal operculum and adjacent posterior insula are the main recipients of spinothalamic afferents in primates. The innermost operculum appears functionally associated with the posterior insula and can be segregated histologically, somatotopically and neurochemically from the more lateral S2 areas...
2018: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/29475601/accelerated-long-term-forgetting-in-focal-epilepsies-with-special-consideration-given-to-patients-with-diagnosed-and-suspected-limbic-encephalitis
#16
Christoph Helmstaedter, Babette Winter, Nico Melzer, Hubertus Lohmann, Juri-Alexander Witt
RATIONALE: Accelerated long-term forgetting (ALF) is a phenomenon found in late onset epilepsy and in transient epileptic amnesia (TEA). Here we evaluated ALF in patients with focal epilepsies and limbic encephalitis (LE) in particular. METHODS: ALF was assessed in 36 patients with focal epilepsy and 154 healthy subjects using an extended version of the Verbal Learning and Memory Test (VLMT), with free recall after 30 min and again after one week. From these patients, 89% had temporal lobe epilepsy; 42% left-lateralized; 39% right; 19% bilateral; 17% were diagnosed with hippocampal sclerosis; 64% displayed features indicating LE; 52% with amygdala pathology, and 61% were antibody positive...
January 31, 2018: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
https://www.readbyqxmd.com/read/29471028/the-structural-and-functional-brain-networks-that-support-human-social-networks
#17
M P Noonan, R B Mars, J Sallet, R I M Dunbar, L K Fellows
Social skills rely on a specific set of cognitive processes, raising the possibility that individual differences in social networks are related to differences in specific brain structural and functional networks. Here, we tested this hypothesis with multimodality neuroimaging. With diffusion MRI (DMRI), we showed that differences in structural integrity of particular white matter (WM) tracts, including cingulum bundle, extreme capsule and arcuate fasciculus were associated with an individual's social network size (SNS)...
February 20, 2018: Behavioural Brain Research
https://www.readbyqxmd.com/read/29456489/hurst-exponent-analysis-of-resting-state-fmri-signal-complexity-across-the-adult-lifespan
#18
Jianxin Dong, Bin Jing, Xiangyu Ma, Han Liu, Xiao Mo, Haiyun Li
Exploring functional information among various brain regions across time enables understanding of healthy aging process and holds great promise for age-related brain disease diagnosis. This paper proposed a method to explore fractal complexity of the resting-state functional magnetic resonance imaging (rs-fMRI) signal in the human brain across the adult lifespan using Hurst exponent (HE). We took advantage of the examined rs-fMRI data from 116 adults 19 to 85 years of age (44.3 ± 19.4 years, 49 females) from NKI/Rockland sample...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29434570/perspectives-on-how-human-simultaneous-multi-modal-imaging-adds-directionality-to-spread-models-of-alzheimer-s-disease
#19
Julia Neitzel, Rachel Nuttall, Christian Sorg
Previous animal research suggests that the spread of pathological agents in Alzheimer's disease (AD) follows the direction of signaling pathways. Specifically, tau pathology has been suggested to propagate in an infection-like mode along axons, from transentorhinal cortices to medial temporal lobe cortices and consequently to other cortical regions, while amyloid-beta (Aβ) pathology seems to spread in an activity-dependent manner among and from isocortical regions into limbic and then subcortical regions. These directed connectivity-based spread models, however, have not been tested directly in AD patients due to the lack of an in vivo method to identify directed connectivity in humans...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29423004/herpes-zoster-chronification-to-postherpetic-neuralgia-induces-brain-activity-and-grey-matter-volume-change
#20
Song Cao, Bangyong Qin, Yi Zhang, Jie Yuan, Bao Fu, Peng Xie, Ganjun Song, Ying Li, Tian Yu
OBJECTIVE: Herpes zoster (HZ) can develop into postherpetic neuralgia (PHN), which is a chronic neuropathic pain (NP). Whether the chronification from HZ to PHN induced brain functional or structural change is unknown and no study compared the changes of the same brains of patients who transited from HZ to PHN. We minimized individual differences and observed whether the chronification of HZ to PHN induces functional and pain duration dependent grey matter volume (GMV) change in HZ-PHN patients...
2018: American Journal of Translational Research
keyword
keyword
23590
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"