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https://www.readbyqxmd.com/read/29245175/development-and-testing-of-a-hybrid-measure-of-muscle-strength-in-juvenile-dermatomyositis-for-use-in-routine-care
#1
Giulia Camilla Varnier, Silvia Rosina, Cristina Ferrari, Angela Pistorio, Alessandro Consolaro, Francesca Bovis, Sara Dalprà, Clarissa Pilkington, Susan Maillard, Adele Civino, Elena Tsitsami, Jaime de Inocencio, Marija Jelusic, Jelena Vojinovic, Graciela Espada, Balahan Makay, Maria Martha Katsicas, Polixeni Pratsidou-Gertsi, Dragana Lazarevic, Anand Prahalad Rao, Denise Pires Marafon, Nicolino Ruperto, Alberto Martini, Angelo Ravelli
OBJECTIVE: To develop and test a hybrid measure of muscle strength for juvenile dermatomyositis (JDM), which is based on the combination of the Manual Muscle Testing 8 (MMT8) and the Childhood Myositis Assessment Scale (CMAS), but is more comprehensive than the former and more feasible than the latter. METHODS: The hybrid MMT/CMAS (hMC) is composed of all 8 items of the MMT8 and 3 items of the CMAS: 1) time of head lift; 2) assessment of abdominal muscles; 3) floor rise...
December 15, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/29245168/-school-entrance-examination-for-lateral-entrants-what-can-and-what-should-they-be-able-to-do-a-discussion-contribution-based-on-the-data-from-the-health-authority-frankfurt-am-main-2006-2016
#2
Maria Karathana, Bernhard Krackhardt, Manuela Schade, Ursel Heudorf
Question The medical investigation of school beginners is one of the essential tasks of the child and youth services of the health authorities. While in all federal states in Germany, the examination of all school beginners is legally clearly stipulated, the situation for "lateral entry", that is, children of school age, who are moving from a foreign country to a local German community and attending school there, is not clearly regulated in the respective school laws. This article presents the experiences of the lateral entry investigations in Frankfurt am Main...
December 15, 2017: Das Gesundheitswesen
https://www.readbyqxmd.com/read/29245156/selection-and-targeting-of-epcam-protein-by-ssdna-aptamer
#3
Walhan Alshaer, Nida Ababneh, Mamon Hatmal, Heba Izmirli, Moujab Choukeife, Alaa Shraim, Nour Sharar, Aya Abu-Shiekah, Fadwa Odeh, Abeer Al Bawab, Abdalla Awidi, Said Ismail
Aptamers are molecules that reveal highly complex and refined molecular recognition properties. These molecules are capable of binding with high affinity and selectivity to targets, ranging from small molecules to whole living cells. Several aptamers have been selected for targeting cellular proteins and they have also used in developing therapeutics and diagnostic strategies. Epithelial cell adhesion molecule (EpCAM) is considered as a cancer stem cell (CSC) biomarker and one of the most promising targets for aptamer selection against CSCs...
2017: PloS One
https://www.readbyqxmd.com/read/29245145/comparative-leaching-of-six-toxic-metals-from-raw-and-chemically-stabilized-mswi-fly-ash-using-citric-acid
#4
Huawei Wang, Xinxiu Fan, Ya-Nan Wang, Weihua Li, Yingjie Sun, Meili Zhan, Guizhi Wu
The leaching behavior of six typical toxic metals (Pb, Zn, Cr, Cd, Cu and Ni) from raw and chemically stabilized (phosphate and chelating agent) municipal solid waste incineration (MSWI) fly ash were investigated using citric acid. Leaching tests indicated that phosphate stabilization can effectively decrease the leaching of Zn, Cd and Cr; whereas chelating agent stabilization shows a strong ability to lower the release of Pb, Cd and Cu, but instead increases the solubility of Zn and Cr at low pH conditions...
December 12, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/29245144/the-myorobot-a-novel-automated-biomechatronics-system-to-assess-voltage-ca2-biosensors-and-active-passive-biomechanics-in-muscle-and-biomaterials
#5
M Haug, B Reischl, G Prölß, C Pollmann, T Buckert, C Keidel, S Schürmann, M Hock, S Rupitsch, M Heckel, T Pöschel, T Scheibel, C Haynl, L Kiriaev, S I Head, O Friedrich
We engineered an automated biomechatronics system, MyoRobot, for robust objective and versatile assessment of muscle or polymer materials (bio-)mechanics. It covers multiple levels of muscle biosensor assessment, e.g. membrane voltage or contractile apparatus Ca2+ ion responses (force resolution 1µN, 0-10mN for the given sensor; [Ca2+] range ~ 100nM-25µM). It replaces previously tedious manual protocols to obtain exhaustive information on active/passive biomechanical properties across various morphological tissue levels...
December 7, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/29245135/acidogenic-fermentation-of-iron-enhanced-primary-sedimentation-sludge-under-different-ph-conditions-for-production-of-volatile-fatty-acids
#6
Lin Lin, Xiao-Yan Li
Iron-based chemically enhanced primary sedimentation (CEPS) is increasingly adopted for wastewater treatment in mega cities, producing a large amount of sludge (Fe-sludge) with a high content of organics for potential organic resource recovery. In this experimental study, acidogenic fermentation was applied treat FeCl3-based CEPS sludge for production of volatile fatty acids (VFAs) at different pHs. Batch fermentation tests on the Fe-sludge with an organic content of 10 g-COD/L showed that the maximum VFAs production reached 2782...
December 6, 2017: Chemosphere
https://www.readbyqxmd.com/read/29245126/geographic-and-social-disparities-in-exposure-to-air-neurotoxicants-at-u-s-public-schools
#7
Sara E Grineski, Timothy W Collins
Children are especially vulnerable to the health and developmental impacts of environmental hazards and they spend significant portions of their days at school. Yet there are no national-level studies examining school-level environmental inequalities and few have examined disparate exposure to neurological air toxicants, even though chronic exposure to air pollution impacts children's brain functioning. We paired information about the geographic locations and demographics of each public school in the US with air neurotoxicant exposure estimates pertaining to 24 known neurotoxicants included in the US Environmental Protection Agency's National Air Toxics Assessment...
December 12, 2017: Environmental Research
https://www.readbyqxmd.com/read/29245124/bisphenol-and-phthalate-concentrations-and-its-determinants-among-pregnant-women-in-a-population-based-cohort-in-the-netherlands-2004-5
#8
Elise M Philips, Vincent W V Jaddoe, Alexandros G Asimakopoulos, Kurunthachalam Kannan, Eric A P Steegers, Susana Santos, Leonardo Trasande
BACKGROUND: Exposure to bisphenols and phthalates in pregnancy may lead to adverse health effects in women themselves and their offspring. OBJECTIVE: To describe first trimester bisphenol and phthalate urine concentrations, including bisphenol and phthalate replacements, and determine nutritional, socio-demographic and lifestyle related determinants. METHODS: In a population-based prospective cohort of 1396 mothers, we measured first trimester bisphenol, phthalate and creatinine urine concentrations (samples collected in 2004-2005, median gestational age 12...
December 12, 2017: Environmental Research
https://www.readbyqxmd.com/read/29245121/co-doped-tio2-nanostructures-as-a-strong-antibacterial-agent-and-self-cleaning-cover-synthesis-characterization-and-investigation-of-photocatalytic-activity-under-uv-irradiation
#9
Maryam Hosseini-Zori
The aim of this work was synthesis and investigation of various properties of Co-doped titanium dioxide nanostructures. However, dopant has no effect on XRD pattern of the host but it can influence on the various characteristics of host such as optical and electrical properties. The results of optical properties showed that absorption energy of TiO2 decreases in presence of cobalt as dopant. Red-shift in absorption spectrum that may be due to the excitation of 3d electrons of Co ions to the conduction band of TiO2 can be considered as a strong evidence to confirm the presence of Co as dopant in TiO2 lattice...
December 8, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29245114/subacromial-impingement-syndrome-an-electromyographic-study-of-shoulder-girdle-muscle-fatigue
#10
Omid Alizadehkhaiyat, Margaret M Roebuck, Ahmed T Makki, Simon P Frostick
Muscle fatigue affecting glenohumeral and/or scapular muscles is suggested as one of the contributing factors to the development of subacromial impingement syndrome (SAIS). Nonetheless, the fatigability of shoulder girdle muscles in association with the pathomechanics of SAIS has not been reported. This study aimed to measure and compare fatigue progression within the shoulder girdle musculature of patients and healthy controls. 75 participants including 39 patients (20 females; 19 males) and 36 healthy controls (15 females; 21 males) participated in the study...
December 7, 2017: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/29245102/random-responses-inflate-statistical-estimates-in-heavily-skewed-addictions-data
#11
Kevin M King, Dale S Kim, Connor J McCabe
BACKGROUND: Some respondents may respond at random to self-report surveys, rather than responding conscientiously (Meade and Craig, 2012), and this has only recently come to the attention of researchers in the addictions field (Godinho et al., 2016). Almost no research in the published addictions literature has reported screening for random responses. We illustrate how random responses can bias statistical estimates using simulated and real data, and how this is especially problematic in skewed data, as is common with substance use outcomes...
December 9, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29245091/specificity-in-mediated-pathways-by-anxiety-symptoms-linking-adolescent-stress-profiles-to-depressive-symptoms-results-of-a-moderated-mediation-approach
#12
Frederick Anyan, Boris Bizumic, Odin Hjemdal
BACKGROUND: We investigated the specificity in mediated pathways that separately link specific stress dimensions through anxiety to depressive symptoms and the protective utility of resilience. Thus, this study goes beyond lumping together potential mediating and moderating processes that can explain the relations between stress and (symptoms of) psychopathology and the buffering effect of resilience. METHODS: Ghanaian adolescents between 13 and 17 years (female = 285; male = 244) completed the Adolescent Stress Questionnaire (ASQ), Spielberger State Anxiety Inventory (STAI), Short Mood Feeling Questionnaire (SMFQ) and the Resilience Scale for Adolescents (READ)...
December 7, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29245087/genotyping-of-common-egfr-mutations-in-lung-cancer-patients-by-electrochemical-biosensor
#13
Xiu-Hua Weng, Xiong-Wei Xu, Chang-Lian Wang, Wei-Wei Lin, Ai-Lin Liu, Wei Chen, Xin-Hua Lin
In this study, we constructed a sandwich-type biosensor to identify six common types of mutations in exon 19 of the epidermal growth factor receptor (EGFR) gene, and tested them using tissue samples from patients with non-small cell lung carcinomas. Considering the characteristics that different locations of non-complementary in DNA probes resulting in different hybridization efficiency, we investigated the design of DNA capture probes with varying non-complementary sequence locations in an effort to optimize the selectivity of the biosensor...
December 9, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/29245083/concordance-between-the-wada-test-and-neuroimaging-lateralization-influence-of-imaging-modality-fmri-and-meg-and-patient-experience
#14
Steven Kemp, Garreth Prendergast, Theodoros Karapanagiotidis, Gus Baker, Thomas P Kelly, Tufail Patankar, Simon S Keller
The Wada test remains the traditional test for lateralizing language and memory function prior to epilepsy surgery. Functional imaging, particularly functional MRI (fMRI), has made progress in the language domain, but less so in the memory domain. Magnetoencephalography (MEG) has received less research attention, but shows promise, particularly for language lateralization. We recruited a consecutive sample of 19 patients with epilepsy who had completed presurgical work-up, including the Wada test, and compared fMRI (memory) and MEG (language and memory) with Wada test results...
December 12, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29245081/safety-in-stigmatizing-instrumental-stigma-beliefs-and-protective-sexual-behavior-in-sub-saharan-africa
#15
David A Cort, Hsin Fei Tu
How are people's expression of HIV stigma beliefs connected to their own personal decisions concerning safe sexual practices? Does this relationship vary across countries and by the national context in which people reside? To answer these questions, we develop and test individual, contextual, and cross-level interactional hypotheses of the impact of instrumental HIV stigma attitudes on several measures of protective sexual behavior. Using Demographic and Health Survey data from 467,656 unpartnered individuals across 34 sub-Saharan African countries, we first find that counterintuitively, conservative HIV stigma attitudes are associated with lower likelihoods of participating in all types of protective sexual behaviors...
December 9, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/29245077/no-overdiagnosis-in-the-norwegian-breast-cancer-screening-program-estimated-by-combining-record-linkage-and-questionnaire-information-in-the-norwegian-women-and-cancer-study
#16
Eiliv Lund, Aurelie Nakamura, Jean-Christophe Thalabard
BACKGROUND: The Norwegian Breast Cancer Screening Program (NBCSP) was implemented across the country in 2005 and has been criticised for potential 'overdiagnosis', i.e. a breast cancer diagnosis that otherwise would not have been detected or treated in a woman's lifetime. We aimed to estimate overdiagnosis in the NBCSP based on the Norwegian Women and Cancer (NOWAC) study using both questionnaire information and record linkage information from NBCSP. METHOD: For 124,978 women aged 49-79 years from the NOWAC study, information on screened women could be cross-validated from the NBCSP database...
December 12, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/29245074/fabrication-characterization-and-photoelectrochemical-activity-of-tungsten-copper-co-sensitized-tio2-nanotube-composite-photoanodes
#17
Mohamad Mohsen Momeni, Yousef Ghayeb, Farzaneh Ezati
Tungsten-copper co-sensitized TiO2 nanotube films on titanium substrate, used as photoanodes in photoelectrochemical (PEC) water splitting to produce hydrogen, have been synthesized via anodization and chemical bath deposition (CBD) methods. Field emission scanning electron microscopy (FE-SEM), energy dispersive X-ray spectroscopy (EDX) and X-ray diffraction (XRD) were used to study the morphology and elemental composition of the synthetic samples. UV-Vis diffuse reflection spectroscopy (UV-Vis DRS) was sued to investigate the optical features of the samples...
December 6, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29245071/dual-task-training-in-older-adults-the-effect-of-additional-motor-tasks-on-mobility-performance
#18
Paolo Riccardo Brustio, Emanuela Rabaglietti, Sabrina Formica, Monica Emma Liubicich
OBJECTIVES: Dual-task (DT) performance is common to most activities of daily living and difficulties in DT activities may reduce quality of life in older adults. This study investigated the effect of DT training in a sample of older adults. METHODS: Sixty older adults (mean=74.4±3.1years) participated in the study. Twenty-two older adults were included in the control (CG), 19 in the single-task (ST) training and 19 in DT training group. ST group received balance and walking training twice a week for16 weeks, while DT training group performed the same training with additional motor tasks...
December 10, 2017: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29245057/a-new-randomized-kaczmarz-based-kernel-canonical-correlation-analysis-algorithm-with-applications-to-information-retrieval
#19
Jia Cai, Yi Tang
Canonical correlation analysis (CCA) is a powerful statistical tool for detecting the linear relationship between two sets of multivariate variables. Kernel generalization of it, namely, kernel CCA is proposed to describe nonlinear relationship between two variables. Although kernel CCA can achieve dimensionality reduction results for high-dimensional data feature selection problem, it also yields the so called over-fitting phenomenon. In this paper, we consider a new kernel CCA algorithm via randomized Kaczmarz method...
December 2, 2017: Neural Networks: the Official Journal of the International Neural Network Society
https://www.readbyqxmd.com/read/29245055/high-proportion-of-abnormal-pap-smear-tests-and-cervical-dysplasia-in-women-with-cystic-fibrosis
#20
Christine Rousset-Jablonski, Quitterie Reynaud, Raphaëlle Nove-Josserand, Isabelle Ray-Coquard, Yahia Mekki, François Golfier, Isabelle Durieu
OBJECTIVES: Insufficient gynecological follow-up and cervical screening has been reported in women with cystic fibrosis (CF). Some of these patients will require a pulmonary transplantation, known to be associated with a higher risk of cervical dysplasia. The aim of this study was to explore the results of cervical screening in adult women with CF, and to report the prevalence of abnormal pap smear tests in this population. STUDY DESIGN: We retrospectively analyzed medical records of sexually active women with CF who attended a gynecological consultation in Lyon University CF referral center between June 2014 and December 2015...
December 9, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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