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https://www.readbyqxmd.com/read/28749611/morphology-ultrastructure-and-molecular-phylogeny-of-rozella-multimorpha-a-new-species-in-cryptomycota
#1
Peter M Letcher, Joyce E Longcore, Timothy Y James, Domingos S Leite, D Rabern Simmons, Martha J Powell
Increasing numbers of sequences of basal fungi from environmental DNA studies are being deposited in public databases. Many of these sequences remain unclassified below the phylum level because sequence information from identified species is sparse. Lack of basic biological knowledge due to a dearth of identified species is extreme in Cryptomycota, a new phylum widespread in the environment and phylogenetically basal within the fungal lineage. Consequently, we are attempting to fill gaps in the knowledge of Rozella, the best-known genus in this lineage...
July 27, 2017: Journal of Eukaryotic Microbiology
https://www.readbyqxmd.com/read/28749605/housing-tenure-as-a-focus-for-reducing-inequalities-in-the-home-safety-environment-evidence-from-growing-up-in-new-zealand
#2
Sarah Berry, Polly Atatoa Carr, Bridget Kool, Jatender Mohal, Susan Morton, Cameron Grant
OBJECTIVES: To determine whether specific demographic characteristics are associated with the presence or absence of household safety strategies. METHODS: This study was conducted within Growing Up in New Zealand, a contemporary longitudinal study of New Zealand (NZ) children. Multivariable analyses were used to examine the maternal (self-prioritised ethnicity, education, age, self-reported health) and household (area-level deprivation, tenure, crowding, residential mobility, dwelling type) determinants of household safety strategies being present in the homes of young children...
July 27, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/28749598/beyond-fxr-to-target-new-therapies-for-nafld
#3
EDITORIAL
Xiaoying Liu, Richard M Green
No abstract text is available yet for this article.
July 27, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28749587/regional-survey-supports-national-initiative-for-water-only-schools-in-new-zealand
#4
Osman David Mansoor, Rukhsana Ali, Ruth Richards
OBJECTIVE: To support a national initiative to remove sugary drinks from schools and limit drinks to water or unflavoured milk ('water-only'). METHODS: We emailed all 201 schools with primary school aged children in the Greater Wellington region with a survey on (1) current status of, (2) support needs for, and (3) barriers to or lessons learned from, a 'water-only' school policy. RESULTS: Only 78 (39%) of schools responded. Most supported 'water-only': 22 (28%) had implemented a policy; 10 (13%) in process of doing so; 22 (28%) were considering it; and 12 (15%) were 'water-only', but did not have a policy...
July 27, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/28749579/a-new-type-of-neurons-for-machine-learning
#5
Fenglei Fan, Wenxiang Cong, Ge Wang
In machine learning, the use of an artificial neural network is the mainstream approach. Such a network consists of layers of neurons. These neurons are of the same type characterized by the two features: (1) an inner product of an input vector and a matching weighting vector of trainable parameters and (2) a nonlinear excitation function. Here we investigate the possibility of replacing the inner product with a quadratic function of the input vector, thereby upgrading the 1(st) order neuron to the 2(nd) order neuron, empowering individual neurons, and facilitating the optimization of neural networks...
July 27, 2017: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/28749578/a-descriptive-study-of-intentional-self-poisoning-from-new-zealand-national-registry-data
#6
Eeva-Katri Kumpula, Shyamala Nada-Raja, Pauline Norris, Paul Quigley
OBJECTIVE: Understanding which population groups intentionally poison themselves by overdose and which substances are used are key to developing prevention efforts for such injuries. This paper uses Ministry of Health (MOH) data to explore the demographic characteristics of those who intentionally self-poison and the substances used, identifies limitations of existing data collections and makes recommendations for the future. METHODS: MOH mortality data from 2000 to 2012, and public hospital presentation data from 2000-2014 of cases of intentional self-poisoning (ISP), and poisoning of undetermined intent (UDP), were examined...
July 27, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/28749572/new-zealand-adolescents-discouragement-of-smoking-among-their-peers
#7
Louise Marsh, Ella Iosua, Rob McGee, Joanna White
OBJECTIVE: This study examines the extent to which young people are acting as 'agents of change' in discouraging smoking among their peers. METHODS: This study used data from a survey of 2,919 New Zealand secondary school students who participated in the 2014 national Youth In-depth Survey. Relevant questions were used to assess the extent to which students engaged in behaviours to discourage or promote smoking among their peers. RESULTS: About half of all students reported some form of behaviour discouraging others from smoking, while only one in ten reported encouraging smoking...
July 27, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/28749543/new-multi-responsive-chromic-soft-materials-dynamic-interconversion-of-short-2-7-dicyanomethylenecarbazole-based-biradicaloid-and-corresponding-cyclophane-tetramer
#8
Maria Carmen Ruiz Delgado, Deliang Wang, Cristina Capel Ferrón, Jie Li, Sergio Gámez-Valenzuela, Rocio Ponce Ortiz, Juan T López Navarrete, Víctor Hernández Jolin, Xiaodi Yang, Miriam Peña Álvarez, Valentín García Baonza, František Hartl, Hongxiang Li
Herein, we report a quinodimethane-type molecule, 2,7-dicyanomethylene-9-(2-ethylhexyl)carbazole (1), one of the shortest π-conjugated biradicaloids reported to be stable in solution at ambient. This carbazole-based quinoidal precursor is able to form a macrocyclic -bonded tetramer (2). The resolved single crystal X-ray structure of tetramer 2 shows that four molecules of 1 are linked together through four long (CN)2C-C(CN)2 bonds (1.631 Å) resulting from coupling of the unpaired electrons in biradicaloid 1...
July 27, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28749540/declining-prevalence-of-undiagnosed-hiv-in-melbourne-results-from-community-based-bio-behavioural-studies-of-gay-and-bisexual-men
#9
Mark Stoové, Jason Asselin, Alisa Pedrana, Toby Lea, Margaret Hellard, David Wilson, Garrett Prestage, John de Wit, Martin Holt
OBJECTIVE: To measure changes in undiagnosed HIV among gay and bisexual men (GBM) in Melbourne. METHODS: Undiagnosed HIV was compared between GBM recruited anonymously in 2008 in gay venues only and GBM anonymously or confidentially (results delivery) recruited in 2014 at gay venues and a community festival. Surveys were completed and oral fluid specimens collected for HIV testing; positive tests among GBM reporting being HIV-negative or unknown/untested were classified as undiagnosed...
July 27, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/28749533/charmm-force-field-and-molecular-dynamics-simulations-of-protonated-polyethylenimine
#10
Titus Adrian Beu, Alexandra Farcaş
As a gene delivery vector, polyethylenimine (PEI) shows one of the highest transfection efficiencies, while effectively protecting DNA from enzyme degradation. The distinctive charge pattern of protonated PEI is widely considered responsible for fundamental process such as DNA condensation into PEI/DNA polyplexes (which are able to enter cells via endocytosis), proton sponge effect (which triggers the release of polyplexes from endosome), and release of DNA from polyplexes (to be further processed inside the nucleus)...
July 27, 2017: Journal of Computational Chemistry
https://www.readbyqxmd.com/read/28749526/adaptation-to-the-spanish-population-of-the-substance-use-risk-profile-scale-surps-and-psychometric-properties
#11
Fermín Fernández-Calderón, Carmen Díaz-Batanero, Antonio J Rojas-Tejada, Natalie Castellanos-Ryan, Óscar M Lozano-Rojas
The identification of different personality risk profiles for substance misuse is useful in preventing substance-related problems. This study aims to test the psychometric properties of a new version of the Substance Use Risk Profile Scale (SURPS) for Spanish college students. Cross-sectional study with 455 undergraduate students from four Spanish universities. A new version of the SURPS, adapted to the Spanish population, was administered with the Beck Hopelessness Scale, the UPPS-P Impulsive Behavior Scale, the State-Trait Anxiety Inventory (STAI) and the Alcohol Use Disorders Identification Test (AUDIT)...
July 14, 2017: Adicciones
https://www.readbyqxmd.com/read/28749512/excited-state-intermolecular-proton-transfer-dependent-on-the-substitution-pattern-of-anthracene-diurea-compounds-involved-in-fluorescent-on-1-off-on-2-response-by-the-addition-of-acetate-ions
#12
Hisato Matsumoto, Yoshinobu Nishimura, Tatsuo Arai
We report anthracene-diurea compounds which behave as anion sensors based on the fluorescence emission regulated by the substitution position on the anthracene ring. Anthracene-diurea compounds exhibit different excited-state intermolecular proton transfer (ESIPT) reactions depending on the pattern of the substituents. Three new anthracene-diurea compounds that have two phenylurea groups substituted at different positions on anthracene were synthesized. These compounds formed complexes with acetate ions through intermolecular hydrogen bonding between N-H and C[double bond, length as m-dash]O moieties in the ground state...
July 27, 2017: Organic & Biomolecular Chemistry
https://www.readbyqxmd.com/read/28749505/the-influence-of-surface-area-porous-structure-and-surface-state-on-the-supercapacitor-performance-of-titanium-oxynitride-implications-for-a-nanostructuring-strategy
#13
Eun Joo Lee, Lanlee Lee, Muhammad Awais Abbas, Jin Ho Bang
A recent surge of interest in metal (oxy)nitride materials for energy storage devices has given rise to the rapid development of various nanostructuring strategies for these materials. In supercapacitor applications, early transition metal (oxy)nitrides have been extensively explored, among which titanium oxynitride stands out due to its great potential for charge storage. Despite recent advances in supercapacitors based on titanium oxynitride, many underlying factors governing their capacitive performance remain elusive...
July 27, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28749497/laterally-functionalized-pillar-5-arene-a-new-building-block-for-covalent-self-assembly
#14
Shuang Fu, Guo An, Hongcheng Sun, Quan Luo, Chunxi Hou, Jiayun Xu, Zeyuan Dong, Junqiu Liu
Laterally functionalized pillar[5]arenes were synthesized for the first time by bromination at the methylene bridge of dimethoxypillar[5]arene. The synthesized molecule was then used as a novel building block by being covalently self-assembled into polymer nanocapsules and 2D polymer films.
July 27, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28749492/a-cobalt-nitrosyl-complex-with-a-hindered-hydrotris-pyrazolyl-borate-coligand-detailed-electronic-structure-and-reactivity-towards-dioxygen
#15
Kiyoshi Fujisawa, Shoko Soma, Haruka Kurihara, Hai T Dong, Max Bilodeau, Nicolai Lehnert
The cobalt-nitrosyl complex [Co(NO)(L3)] is supported by a highly hindered tridentate nitrogen ligand, hydrotris(3-tertiary butyl-5-isopropyl-1-pyrazolyl)borate (denoted as L3(-)), and shows a linear Co-N-O unit. This complex was prepared by the reaction of the potassium salt of L3(-) with the cobalt-nitrosyl precursor [Co(NO)2(tmeda)](BPh4) (tmeda = N,N,N,'N'-tetramethylethylenediamine). The obtained cobalt-nitrosyl complex as well as the corresponding products from the reaction with dioxygen, [Co(η(2)-O2N)(L3)] and [Co(η(2)-O2NO)(L3)], were characterised by X-ray crystallography and a number of spectroscopic methods including IR/far-IR, UV-Vis, and NMR spectroscopy...
July 27, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28749477/mapping-the-genomic-landscape-of-inherited-retinal-disease-genes-prioritizes-genes-prone-to-coding-and-noncoding-copy-number-variations
#16
Kristof Van Schil, Sarah Naessens, Stijn Van de Sompele, Marjolein Carron, Alexander Aslanidis, Caroline Van Cauwenbergh, Anja Kathrin Mayer, Mattias Van Heetvelde, Miriam Bauwens, Hannah Verdin, Frauke Coppieters, Michael E Greenberg, Marty G Yang, Marcus Karlstetter, Thomas Langmann, Katleen De Preter, Susanne Kohl, Timothy J Cherry, Bart P Leroy, Elfride De Baere
PurposePart of the hidden genetic variation in heterogeneous genetic conditions such as inherited retinal diseases (IRDs) can be explained by copy-number variations (CNVs). Here, we explored the genomic landscape of IRD genes listed in RetNet to identify and prioritize those genes susceptible to CNV formation.MethodsRetNet genes underwent an assessment of genomic features and of CNV occurrence in the Database of Genomic Variants and literature. CNVs identified in an IRD cohort were characterized using targeted locus amplification (TLA) on extracted genomic DNA...
July 27, 2017: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/28749462/keratin-23-promotes-telomerase-reverse-transcriptase-expression-and-human-colorectal-cancer-growth
#17
Ningning Zhang, Rui Zhang, Kun Zou, Wendan Yu, Wei Guo, Yingying Gao, Jia Li, Mei Li, Yidi Tai, Wenlin Huang, Chun Song, Wuguo Deng, Xiaonan Cui
The overexpression of human telomerase reverse transcriptase (hTERT) has been associated with the proliferation and migration of colorectal cancer (CRC) cells. We investigated the roles of KRT23 and hTERT in promoting CRC cell proliferation and migration. We verified the relationship between KRT23 and hTERT in CRC using streptavidin-agarose pulldown and chromatin immunoprecipitation (ChIP) assays. One hundred and fifty-four human CRC specimens were analyzed using immunohistochemistry. The roles of KRT23 and hTERT in cell growth and migration were studied using siRNA and lentiviruses in vivo and in vitro...
July 27, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/28749451/characterization-of-two-historic-smallpox-specimens-from-a-czech-museum
#18
Petr Pajer, Jiri Dresler, Hana Kabíckova, Libor Písa, Pavel Aganov, Karel Fucik, Daniel Elleder, Tomas Hron, Vitezslav Kuzelka, Petr Velemínsky, Jana Klimentova, Alena Fucikova, Jaroslav Pejchal, Rita Hrabakova, Vladimir Benes, Tobias Rausch, Pavel Dundr, Alexander Pilin, Radomir Cabala, Martin Hubalek, Jan Stríbrny, Markus H Antwerpen, Hermann Meyer
Although smallpox has been known for centuries, the oldest available variola virus strains were isolated in the early 1940s. At that time, large regions of the world were already smallpox-free. Therefore, genetic information of these strains can represent only the very last fraction of a long evolutionary process. Based on the genomes of 48 strains, two clades are differentiated: Clade 1 includes variants of variola major, and clade 2 includes West African and variola minor (Alastrim) strains. Recently, the genome of an almost 400-year-old Lithuanian mummy was determined, which fell basal to all currently sequenced strains of variola virus on phylogenetic trees...
July 27, 2017: Viruses
https://www.readbyqxmd.com/read/28749446/seamline-determination-based-on-pkgc-segmentation-for-remote-sensing-image-mosaicking
#19
Qiang Dong, Jinghong Liu
This paper presents a novel method of seamline determination for remote sensing image mosaicking. A two-level optimization strategy is applied to determine the seamline. Object-level optimization is executed firstly. Background regions (BRs) and obvious regions (ORs) are extracted based on the results of parametric kernel graph cuts (PKGC) segmentation. The global cost map which consists of color difference, a multi-scale morphological gradient (MSMG) constraint, and texture difference is weighted by BRs. Finally, the seamline is determined in the weighted cost from the start point to the end point...
July 27, 2017: Sensors
https://www.readbyqxmd.com/read/28749443/study-of-the-interactions-of-bovine-serum-albumin-with-the-new-anti-inflammatory-agent-4-1-3-dioxo-1-3-dihydro-2h-isoindol-2-yl-n-4-ethoxy-phenyl-methylidene-benzohydrazide-using-a-multi-spectroscopic-approach-and-molecular-docking
#20
Tanveer A Wani, Ahmed H Bakheit, Abdul-Rahman A Al-Majed, Mashooq A Bhat, Seema Zargar
The lipophilic derivative of thalidomide (4-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)-N'-[(4-ethoxyphenyl)methylidene]benzohydrazide, 6P) was synthesized to enhance its characteristics and efficacy. Earlier studies have proved the immunomodulatory and anti-inflammatory effects of 6P. In this study the interaction between bovine serum albumin (BSA) and 6P was studied using a multi-spectroscopic approach which included UV spectrophotometry, spectrofluorimetry and three dimensional spectrofluorometric and molecular docking studies...
July 27, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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