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https://www.readbyqxmd.com/read/28647901/in-vivo-visualization-of-the-locus-coeruleus-in-humans-quantifying-the-test-retest-reliability
#1
Klodiana-Daphne Tona, Max C Keuken, Mischa de Rover, Egbert Lakke, Birte U Forstmann, Sander Nieuwenhuis, Matthias J P van Osch
The locus coeruleus (LC) is a brainstem nucleus involved in important cognitive functions. Recent developments in neuroimaging methods and scanning protocols have made it possible to visualize the human LC in vivo by utilizing a T1-weighted turbo spin echo (TSE) scan. Despite its frequent use and its application as a biomarker for tracking the progress of monoaminergic-related neurodegenerative diseases, no study to date has investigated the reproducibility and inter-observer variability of LC identification using this TSE scan sequence...
June 24, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28647618/genetic-and-ecological-processes-promoting-early-diversification-in-the-lowland-mesoamerican-bat-sturnira-parvidens-chiroptera-phyllostomidae
#2
Giovani Hernández-Canchola, Livia León-Paniagua
With 22 species, Sturnira is the most speciose genus of frugivorous Neotropical bats. Sturnira parvidens inhabits lowland tropical areas from Mexico to Central America. The elevation of this taxon to species level was recent, and discrepancies with respect to its geographic limits and phylogenetic position continue to exist. In order to identify genetic and ecological processes likely involved in the diversification and current distribution of S. parvidens, we evaluated relationships, researched phylogeographic and demographic history, and tested the divergence/conservatism of the climatic niche of this bat...
June 21, 2017: Molecular Phylogenetics and Evolution
https://www.readbyqxmd.com/read/28647430/determining-the-relevant-criteria-for-three-dimensional-vocal-tract-characterization
#3
Rebecca R Vos, Damian T Murphy, David M Howard, Helena Daffern
OBJECTIVE: Soprano singers face a number of specific challenges when singing vowels at high frequencies, due to the wide spacing of harmonics in the voice source. The varied and complex techniques used to overcome these are still not fully understood. Magnetic resonance imaging (MRI) has become increasingly popular in recent years for singing voice analysis. This study proposes a new protocol using three-dimensional MRI to investigate the articulatory parameters relevant to resonance tuning, a technique whereby singers alter their vocal tract to shift its resonances nearer to a voice source harmonic, increasing the amplitude of the sound produced...
June 21, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28645723/doublet-tracer-tests-to-determine-the-contaminant-flushing-properties-of-a-municipal-solid-waste-landfill
#4
N D Woodman, T C Rees-White, R P Beaven, A M Stringfellow, J A Barker
This paper describes a programme of research investigating horizontal fluid flow and solute transport through saturated municipal solid waste (MSW) landfill. The purpose is to inform engineering strategies for future contaminant flushing. Solute transport between injection/abstraction well pairs (doublets) is investigated using three tracers over five separate tests at well separations between 5m and 20m. Two inorganic tracers (lithium and bromide) were used, plus the fluorescent dye tracer, rhodamine-WT. There was no evidence for persistent preferential horizons or pathways at the inter-well scale...
June 7, 2017: Journal of Contaminant Hydrology
https://www.readbyqxmd.com/read/28645590/endoscopic-supracerebellar-transtentorial-approach-to-the-atrium-of-the-lateral-ventricle-preliminary-surgical-and-optical-considerations
#5
Tao Xie, Linjun Zhou, Xiaobiao Zhang, Wei Sun, Hailin Ding, Tengfei Liu, Ye Gu, Chongjing Sun, Fan Hu, Wei Zhu
OBJECTIVE: To report the operative techniques of the endoscopic supracerebellar transtentorial approach (ESTA) to the atrium of the lateral ventricle, especially focusing on the role of the endoscope and analyzing optically related issues. METHODS: A retrospective data review was performed on five patients with lesions in the atrium of the lateral ventricle undergoing the ESTA. The patients were positioned in the three-quarters prone position, and a paramidline linear incision was used...
June 20, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28644871/predicting-the-bounds-of-large-chaotic-systems-using-low-dimensional-manifolds
#6
Asger M Haugaard
Predicting extrema of chaotic systems in high-dimensional phase space remains a challenge. Methods, which give extrema that are valid in the long term, have thus far been restricted to models of only a few variables. Here, a method is presented which treats extrema of chaotic systems as belonging to discretised manifolds of low dimension (low-D) embedded in high-dimensional (high-D) phase space. As a central feature, the method exploits that strange attractor dimension is generally much smaller than parent system phase space dimension...
2017: PloS One
https://www.readbyqxmd.com/read/28644379/physical-forces-may-cause-the-hoxd-gene-cluster-elongation
#7
Spyros Papageorgiou
Hox gene collinearity was discovered be Edward B. Lewis in 1978. It consists of the Hox1, Hox2, Hox3 ordering of the Hox genes in the chromosome from the telomeric to the centromeric side of the chromosome. Surprisingly, the spatial activation of the Hox genes in the ontogenetic units of the embryo follows the same ordering along the anterior-posterior embryonic axis. The chromosome microscale differs from the embryo macroscale by 3 to 4 orders of magnitude. The traditional biomolecular mechanisms are not adequate to comprise phenomena at so divergent spatial domains...
June 23, 2017: Biology
https://www.readbyqxmd.com/read/28643605/novel-simulation-device-for-targeting-tumors-in-laparoscopic-ablation-a-learning-curve-study
#8
Zeljka Jutric, Jan Grendar, William L Brown, Maria A Cassera, Ronald F Wolf, Paul D Hansen, Chet W Hammill
INTRODUCTION: A novel 3-dimensional (3D) guidance system was developed to aid accurate needle placement during ablation. METHODS: Five novices and 5 experienced hepatobiliary surgeons were recruited. Using an agar block with analog tumor, participants targeted under 4 conditions: in-line with the ultrasound plane using ultrasound, in-line using 3D guidance, 45° off-axis using ultrasound, and off-axis using 3D guidance. Time to target the tumor, number of withdrawals, and the National Aeronautics and Space Administration Task Load Index were collected...
June 1, 2017: Surgical Innovation
https://www.readbyqxmd.com/read/28643559/informing-healthcare-waiting-area-design-using-transparency-attributes-a-comparative-preference-study
#9
Shan Jiang, Matthew Powers, David Allison, Ellen Vincent
OBJECTIVE: This study aimed to explore people's visual preference for waiting areas in general hospital environments designed with transparency attributes that fully integrate nature. BACKGROUND: Waiting can be a tedious and frustrating experience among people seeking healthcare treatments and negatively affect their perception of the quality of care. Positive distractions and supportive designs have gained increasing attraction to improve people's waiting experience...
July 2017: HERD
https://www.readbyqxmd.com/read/28643383/multiecho-pseudo-golden-angle-stack-of-stars-thermometry-with-high-spatial-and-temporal-resolution-using-k-space-weighted-image-contrast
#10
Bryant T Svedin, Allison Payne, Bradley D Bolster, Dennis L Parker
PURPOSE: Implement and evaluate a 3D MRI method to measure temperature changes with high spatial and temporal resolution and large field of view. METHODS: A multiecho pseudo-golden angle stack-of-stars (SOS) sequence with k-space weighted image contrast (KWIC) reconstruction was implemented to simultaneously measure multiple quantities, including temperature, initial signal magnitude M(0), transverse relaxation time ( T2*), and water/fat images. Respiration artifacts were corrected using self-navigation...
June 22, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28642674/an-automatic-3d-ct-pet-segmentation-framework-for-bone-marrow-proliferation-assessment
#11
Chuong Nguyen, Joseph Havlicek, Quyen Duong, Sara Vesely, Ronald Gress, Liza Lindenberg, Peter Choyke, Jennifer Holter Chakrabarty, Kirsten Williams
Clinical assessment of bone marrow is limited by an inability to evaluate the marrow space comprehensively and dynamically and there is no current method for automatically assessing hematopoietic activity within the medullary space. Evaluating the hematopoietic space in its entirety could be applicable in blood disorders, malignancies, infections, and medication toxicity. In this paper, we introduce a CT/PET 3D automatic framework for measurement of the hematopoietic compartment proliferation within osseous sites...
September 2016: Proceedings
https://www.readbyqxmd.com/read/28641269/a-model-based-tool-for-the-analysis-and-design-of-gene-regulatory-network
#12
Liliana Ironi, Ettore Lanzarone
Computational and mathematical models have significantly contributed to the rapid progress in the study of gene regulatory networks (GRN), but researchers still lack a reliable model-based framework for computer-aided analysis and design. Such tool should both reveal the relation between network structure and dynamics and find parameter values and/or constraints that enable the simulated dynamics to reproduce specific behaviors. This paper addresses these issues and proposes a computational framework that facilitates network analysis or design...
June 19, 2017: IEEE/ACM Transactions on Computational Biology and Bioinformatics
https://www.readbyqxmd.com/read/28641251/robust-face-recognition-with-kernelized-locality-sensitive-group-sparsity-representation
#13
Shoubiao Tan, Xi Sun, Wentao Chan, Lei Qu, Ling Shao
In this paper, a novel joint sparse representation method is proposed for robust face recognition. We embed both group sparsity and kernelized locality-sensitive constraints into the framework of sparse representation. The group sparsity constraint is designed to utilize the grouped structure information in the training data. The local similarity between test and training data is measured in the kernel space instead of the Euclidian space. As a result, the embedded nonlinear information can be effectively captured, leading to a more discriminative representation...
June 15, 2017: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/28639434/case-of-ileal-herniation-through-the-foramen-of-winslow-diagnosed-preoperatively-by-ct-and-treated-with-laparoscopic-surgery
#14
Yoshitoshi Ichikawa, Akifumi Kanazawa, Nobuhiro Dan, Satoshi Ishikawa, Takaomi Hagi, Gaku Mizojiri, Mituo Tsubakimoto, Hiroshi Oka
A previously healthy 35-year-old man visited the emergency room complaining of epigastric pain and vomiting. The pain was sudden in onset. His blood tests were within normal limits except for a mild neutrophilia of 14 300/μL. Enhanced abdominal CT scan showed the small intestine dilated into the space between the portal vein and inferior vena cava from the foramen of Winslow. Under the diagnosis of herniation through the foramen of Winslow (HFW), we performed emergency laparoscopic surgery. Laparoscopy revealed an internal herniation of the dilated small intestine through the foramen of Winslow...
June 22, 2017: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/28639387/determining-the-orientation-angle-of-directional-leads-for-deep-brain-stimulation-using-computed-tomography-and-digital-x-ray-imaging-a-phantom-study
#15
Alexander Sitz, Mauritius Hoevels, Alexandra Hellerbach, Andreas Gierich, Klaus Luyken, Till A Dembek, Martin Klehr, Jochen Wirths, Veerle Visser-Vandewalle, Harald Treuer
PURPOSE: Orientating the angle of directional leads for deep brain stimulation (DBS) in an axial plane introduces a new degree of freedom that is indicated by embedded anisotropic directional markers. Our aim was to develop algorithms to determine lead orientation angles from computed tomography (CT) and stereotactic x-ray imaging using standard clinical protocols, and subsequently assess the accuracy of both methods. METHODS: In CT the anisotropic marker artifact was taken as a signature of the lead orientation angle and analyzed using discrete Fourier transform of circular intensity profiles...
June 22, 2017: Medical Physics
https://www.readbyqxmd.com/read/28638547/push-out-bond-strength-of-different-endodontic-obturation-material-at-three-different-sites-in-vitro-study
#16
Pankaj Mishra, Anjna Sharma, Sunil Mishra, Manas Gupta
BACKGROUND: The key to success of any root canal therapy is adequate obturation of the prepared root canal space. Root canal sealers are not dimensionally stable and might dissolve partially over a period of time. The objective of this in vitro study is to evaluate the push-out bond strength to intraradicular dentin of two endodontic obturation materials. MATERIAL AND METHODS: Forty extracted single rooted permanent teeth were used. Canals orifice was explored, teeth were instrumented...
June 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28638056/trap-modulated-charge-carrier-transport-in-polyethylene-graphene-nanocomposites
#17
Zhonglei Li, Boxue Du, Chenlei Han, Hang Xu
The role of trap characteristics in modulating charge transport properties is attracting much attentions in electrical and electronic engineering, which has an important effect on the electrical properties of dielectrics. This paper focuses on the electrical properties of Low-density Polyethylene (LDPE)/graphene nanocomposites (NCs), as well as the corresponding trap level characteristics. The dc conductivity, breakdown strength and space charge behaviors of NCs with the filler content of 0 wt%, 0.005 wt%, 0...
June 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28637289/the-importance-of-knowing-when-you-don-t-remember-neural-signaling-of-retrieval-failure-predicts-memory-improvement-over-time
#18
Yana Fandakova, Silvia A Bunge, Carter Wendelken, Peter Desautels, Lauren Hunter, Joshua K Lee, Simona Ghetti
Just as the ability to remember prior events is critical for guiding our decision-making, so too is the ability to recognize the limitations of our memory. Indeed, we hypothesize that neural signaling of retrieval failure promotes more accurate memory judgments over time. To test this hypothesis, we collected longitudinal functional magnetic resonance imaging data from 8 to 9 years olds, 10 to 12 years olds, and adults, with two time points spaced approximately 1.4 years apart (198 scan sessions in total)...
November 23, 2016: Cerebral Cortex
https://www.readbyqxmd.com/read/28637124/recovery-and-creative-practices-in-people-with-severe-mental-illness-evaluating-well-being-and-social-inclusion
#19
Javier Saavedra, Elvira Pérez, Paul Crawford, Samuel Arias
PURPOSE: This mixed (quantitative-qualitative) study evaluates the impact of an artistic workshop on a group of people with severe mental illness (SMI). This study focuses on the impact of creative practices on well-being and social inclusion outcomes. METHOD: After participating in a creative workshop, 31 people diagnosed with a SMI completed pre/post-intervention measures, namely, the Warwick-Edinburgh Mental Well-Being Scale and the Social Inclusion questionnaire...
February 6, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28636950/structural-evidence-of-quercetin-multi-target-bioactivity-a-reverse-virtual-screening-strategy
#20
Diego Carvalho, Margot Paulino, Fabio Polticelli, Florencia Arredondo, Robert J Williams, Juan A Abin-Carriquiry
The ubiquitous flavonoid quercetin is broadly recognized for showing diverse biological and health-promoting effects, such as anti-cancer, anti-inflammatory and cytoprotective activities. The therapeutic potential of quercetin and similar compounds for preventing such diverse oxidative stress-related pathologies has been generally attributed to their direct antioxidant properties. Nevertheless, accumulated evidence indicates that quercetin is also able to interact with multiple cellular targets influencing the activity of diverse signaling pathways...
June 18, 2017: European Journal of Pharmaceutical Sciences
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