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https://www.readbyqxmd.com/read/29642427/laboratory-investigation-comparing-plaque-removal-efficacy-of-two-novel-design-toothbrushes-with-different-brushing-techniques
#1
Wansiri Jansiriwattana, Thitiwan Teparat-Burana
Manufacturers of manual toothbrushes have improved novel brush head designs aimed at achieving good plaque removal even with inadequate brushing technique. This study tested the plaque removal efficacy of two novel designs compared with a flat trimmed toothbrush with different brushing techniques. Two novel-design toothbrushes (Colgate® 360° Surround and Oral-B® Pro-Health™ Clinical Pro-Flex) were tested. The control toothbrush was Butler® GUM 311. Artificial plaque was applied on artificial teeth. Brushing with the modified Bass and horizontal scrub technique was then performed independently...
April 7, 2018: Dentistry journal
https://www.readbyqxmd.com/read/29513242/effectiveness-of-whitening-mouthwashes-on-tooth-color-an-in-vitro-study
#2
Flàvia Pardo Salata Nahsan, Maria Janete Oliveira Reis, Luciana Fàvaro Francisconi-Dos-Rios, Luciana Vasconcelos Leão, Luiz Renato Paranhos
Products for tooth whitening (or tooth color maintenance) that improve smile esthetics have become increasingly popular due to their easy accessibility and low cost. This in vitro study assessed the effect of whitening mouthwash on bovine tooth color. Forty-eight bovine teeth were divided into 3 immersion groups: SL, artificial saliva (control); CLW, Colgate Luminous White; and OBW, Oral-B 3D White. After prophylaxis with pumice, the initial color was measured using the CIE L*a*b* system. Teeth were immersed in the solutions for 2 minutes, 3 times per day, for 30 days...
March 2018: General Dentistry
https://www.readbyqxmd.com/read/29513232/mouthwashes-an-in-vitro-study-of-their-action-on-microbial-biofilms-and-cytotoxicity-to-gingival-fibroblasts
#3
Jonatas Rafael de Oliveira, Kely Karina Belato, Felipe Eduardo de Oliveira, Antonio Olavo Cardoso Jorge, Samira Esteves Afonso Camargo, Luciane Dias de Oliveira
This study evaluated the in vitro antibiofilm effect of 5 different commercial mouthwashes (Cepacol Traditional, Colgate Plax Fresh Mint, Listerine Cool Mint, Oral-B Complete, and Sensodyne) on Candida albicans, Staphylococcus aureus, Enterococcus faecalis, Streptococcus mutans, Escherichia coli, and Pseudomonas aeruginosa. The cytotoxic effect of the mouthwashes on gingival fibroblasts was also analyzed. A colorimetric assay with 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) was used to investigate the viability of biofilms after 48 hours and gingival fibroblasts after 24 hours...
March 2018: General Dentistry
https://www.readbyqxmd.com/read/29430962/effect-of-a-mouthrinse-containing-malva-sylvestris-on-the-viability-and-activity-of-microcosm-biofilm-and-on-enamel-demineralization-compared-to-known-antimicrobials-mouthrinses
#4
Aline Silva Braga, Juliana Gonçalves Pires, Ana Carolina Magalhães
The purpose of this study was to evaluate the antimicrobial (anti-biofilm) and anti-caries (enamel demineralization prevention) effects of Malva sylvestris (Malvatricin® Plus) compared with known antimicrobial mouthrinses. Microcosm biofilm was produced on enamel, using inoculum from pooled human saliva mixed with McBain saliva (0.2% sucrose) for 14 days. The biofilm was treated with mouthrinses for 1 min day-1. Oral-B® Complete, Listerine® Zero and Malvatricin® Plus had the greatest effect on the reduction of biofilm viability (p < 0...
February 11, 2018: Biofouling
https://www.readbyqxmd.com/read/29412362/can-whitening-toothpastes-maintain-the-optical-stability-of-enamel-over-time
#5
Eduardo Moreira da Silva, Juliana Nunes da Silva Meirelles Dória Maia, Carine Gnatiuk Mitraud, Juliana do Espírito Santo Russo, Laiza Tatiana Poskus, José Guilherme Antunes Guimarães
Besides the effects on the health of individuals, cigarette smoking can also interfere with the appearance of their teeth. To evaluate the effect of cigarette smoking-toothbrushing-cycling (CSTC) with whitening toothpastes on the roughness and optical behavior of bovine enamel for eight weeks. Thirty bovine dentin/enamel discs, 8.0 mm in diameter and 2.0 mm thick, were randomly divided into three groups according to the toothpastes: whitening (Colgate Luminous White - CW and Oral B 3D White - OW), and a non-whitening (Colgate - C)...
February 1, 2018: Journal of Applied Oral Science: Revista FOB
https://www.readbyqxmd.com/read/29399703/release-of-nickel-and-chromium-ions-from-orthodontic-wires-following-the-use-of-teeth-whitening-mouthwashes
#6
AmirHossein Mirhashemi, Sahar Jahangiri, MohammadJavad Kharrazifard
BACKGROUND: Corrosion resistance is an important requirement for orthodontic appliances. Nickel and chromium may be released from orthodontic wires and can cause allergic reactions and cytotoxicity when patients use various mouthwashes to whiten their teeth. Our study aimed to assess the release of nickel and chromium ions from nickel titanium (NiTi) and stainless steel (SS) orthodontic wires following the use of four common mouthwashes available on the market. METHODS: This in vitro, experimental study was conducted on 120 orthodontic appliances for one maxillary quadrant including five brackets, one band and half of the required length of SS, and NiTi wires...
February 5, 2018: Progress in Orthodontics
https://www.readbyqxmd.com/read/29215686/are-desensitizing-toothpastes-equally-biocompatible-and-effective-against-microorganisms
#7
Samira Esteves Afonso Camargo, Noala Vicensoto Moreira Milhan, Fernanda de Oliveira Saraiva, Jonatas Rafael de Oliveira, Luciane Dias de Oliveira, Carlos Henrique Ribeiro Camargo
The aims of this study were evaluate cytotoxicity, genotoxicity, antimicrobial activity of desensitizing toothpastes compared to a common one and the surface roughness of tooth enamel submitted to brushing with these toothpastes. Samples of three desensitizing toothpastes (Colgate Sensitive, Sensodyne and Oral B Sensitive) and common toothpaste (Colgate) were placed in contact with gingival human fibroblasts. Cytotoxicity and genotoxocity were measured by MTT assay and micronucleus test. Antimicrobial activity of the toothpastes extracts against C...
September 2017: Brazilian Dental Journal
https://www.readbyqxmd.com/read/29178759/the-abrasive-effect-of-commercial-whitening-toothpastes-on-eroded-enamel
#8
Victor Mosquim, Beatriz Martines Souza, Gerson Aparecido Foratori Junior, Linda Wang, Ana Carolina Magalhães
PURPOSE: To evaluate the in vitro abrasive effect of commercial whitening toothpastes on eroded bovine enamel samples in respect to erosive tooth wear. METHODS: 72 bovine crowns were embedded, polished and subjected to the baseline profile analysis. The samples were then protected in 2/3 of the enamel surface and were randomly assigned to six groups (n= 12/group): G1: Oral-B 3D White, G2: Close-up Diamond Attraction Power White, G3: Sorriso Xtreme White 4D, G4: Colgate Luminous White, G5: Crest (conventional toothpaste), G6:erosion only (control)...
June 2017: American Journal of Dentistry
https://www.readbyqxmd.com/read/29178731/clinical-effect-of-a-manual-toothbrush-with-tapered-filaments-on-dental-plaque-and-gingivitis-reduction
#9
Longxing Ni, Rongying Tang, Tao He, Jinlan Chang, Jiahui Li, Sarah Li, Renzo Alberto Ccahuana-Vasquez, Richard Cheng, Julie Grender
PURPOSE: To evaluate the anti-plaque efficacy (Study 1) and the anti-gingivitis efficacy (Study 2) of a manual toothbrush with tapered bristles compared to marketed control manual toothbrushes. METHODS: Studies 1 and 2 were independent, randomized and controlled, single-center, examiner-blind clinical trials in generally healthy adults. Study 1 included a 2-day acclimation period, followed by a 5-day twice daily toothbrushing test phase with the assigned brush. Baseline and Day 5 pre- and post-brushing plaque levels were assessed via Turesky Modified Quigley-Hein Plaque Index (TMQHPI)...
October 2017: American Journal of Dentistry
https://www.readbyqxmd.com/read/29038700/the-clinical-evaluation-of-vi-one-chlorhexidine-mouthwash-on-plaque-induced-gingivitis-a-double-blind-randomized-clinical-trial
#10
Babak Amoian, Marzyeh Omidbakhsh, Soraya Khafri
BACKGROUND: Chlorhexidine (CHX) is the most effective antiseptic mouthwash to date. Essential oil such as thymol, have inhibitory and biocidal effects a range of bacteria. OBJECTIVE: To determine the effect of mouthwash containing CHX and thymol on plaque induced gingivitis. METHODS: This double-blind randomized clinical trial study was performed on 60 patients with plaque induced gingivitis who were randomly divided into two groups: Group I (CHX/thymol mouthwash-Vi-one) and Group II (CHX mouthwash-Behsa)...
September 2017: Electronic Physician
https://www.readbyqxmd.com/read/29019276/benzo-a-pyrene-induces-lung-toxicity-and-inflammation-in-mice-prevention-by-carvacrol
#11
P Barnwal, A Vafa, S M Afzal, A Shahid, S K Hasan, Alpashree, S Sultana
Benzo(a)pyrene (B(a)P) is an environmental pollutant which causes various lung toxicities. The present study was designed to evaluate the protective effects of carvacrol, a monoterpenic phenol against B(a)P-induced lung toxicity. In this study, Swiss albino mice were pretreated with carvacrol (25 mg/kg and 50 mg/kg) orally for 7 consecutive days before administering oral B(a)P (125 mg/kg). Preventive efficacy of carvacrol was assessed in terms of membrane oxidation, antioxidant enzyme activities, histopathological changes, and inflammatory (iNOS, NF-κB, and COX-2) markers...
January 1, 2017: Human & Experimental Toxicology
https://www.readbyqxmd.com/read/28872728/changes-to-glazed-dental-ceramic-shade-roughness-and-microhardness-after-bleaching-and-simulated-brushing
#12
Carlos Roberto Teixeira Rodrigues, Cecilia Pedroso Turssi, Flávia Lucisano Botelho Amaral, Roberta Tarkany Basting, Fabiana Mantovani Gomes França
PURPOSE: To evaluate shade stability, surface roughness, microhardness, and compressive strength of a glazed feldspathic ceramic subjected to bleaching and simulated brushing. MATERIALS AND METHODS: Eighty-eight glazed feldspathic ceramic specimens were made from microparticulate leucite and divided into eight groups (n = 10). The whitening products used were: Opalescence Trèswhite Supreme (Ultradent), Opalescence®\ PF 15% (Ultradent), and Oral-B 3D White Whitestrips...
September 5, 2017: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/28852631/comparison-of-efficacy-of-manual-and-powered-toothbrushes-in-plaque-control-and-gingival-inflammation-a-clinical-study-among-the-population-of-east-indian-region
#13
Prasad Kulkarni, Dhirendra Kumar Singh, Mohamed Jalaluddin
AIM AND OBJECTIVE: To figure out, analyze and assess the effectiveness of powered toothbrush (Braun/Oral-B two-dimensional) and manual toothbrush (Oral-B40 Regular Advantage Plus) on supragingival plaque and gingival health. MATERIALS AND METHODS: The efficacy of powered toothbrush to that of manual one was compared by using a randomized clinical trial over a 4 weeks period in controlling plaque and gingivitis using gingival index, plaque index (PI), and oral hygiene index...
July 2017: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/28669220/effects-of-octenidine-mouth-rinse-on-apoptosis-and-necrosis-of-human-fibroblasts-and-epithelial-cells-an-in-vitro-study
#14
J Schmidt, V Zyba, K Jung, S Rinke, R Haak, R F Mausberg, D Ziebolz
This study aimed at comparing the cytotoxicity of a new octenidine mouth rinse (MR) on gingival fibroblasts and epithelial cells using different established MRs. Octenidol (OCT), Chlorhexidine 0.2% (CHX), Meridol (MER), Oral B (OB), and control (PBS only) were used. Human primary gingival fibroblasts (HGFIBs) and human primary nasal epithelial cells (HNEPCs) were cultivated in cell-specific media (2 × 10(5) cells/well) and treated with a MR or PBS for 1, 5, and 15 min. All tests were performed in duplicate and repeated 12 times...
July 3, 2017: Drug and Chemical Toxicology
https://www.readbyqxmd.com/read/28609608/voriconazole-concentrations-in-plasma-and-epithelial-lining-fluid-after-inhalation-and-oral-treatment
#15
Charlotte U Andersen, Lene Dahl Sønderskov, Elisabeth Bendstrup, Nina Voldby, Lindsey Cass, John Ayrton, Ole Hilberg
Adverse effects can compromise oral voriconazole treatment of pulmonary aspergillosis. Inhaled low-dose voriconazole may be an alternative treatment. In this study, six patients inhaled 40 mg voriconazole b.i.d. for 2 days, and six patients ingested 400 and 200 mg orally b.i.d. on day one and two, respectively. Blood samples were collected after the first inhalation, and bronchial alveolar lavage fluids and blood samples were collected for measurements of voriconazole 12 hr after the last administration. The concentration of voriconazole in epithelial lining fluid (ELF) was calculated by the urea dilution method...
November 2017: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/28422462/a-comparison-of-the-effect-of-two-power-toothbrushes-on-the-gingival-health-and-plaque-status-of-subjects-with-moderate-gingivitis
#16
Michelle Starke, Marcia Delaurenti, Marilyn Ward, Sonia Souza, Kimberly R Milleman, Jeffery L Milleman
OBJECTIVES: To compare the effect of the Philips Sonicare DiamondClean plus Premium plaque control brush head with the Oral-B 7000 plus CrossAction brush head on gingivitis and supragingival plaque reduction following a 42-day period of home use. METHODS: This was a randomized, parallel, examiner-blind, prospective clinical trial conducted on generally healthy subjects. Eligible subjects met the following eligibility criteria: age 18-65, non-smoker, routine manual toothbrush user, ≥ 50 sites of gingival bleeding per the Gingival Bleeding Index (GBI), and ≥ 1...
March 2017: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28355362/controlled-clinical-trial-addressing-teeth-whitening-with-hydrogen-peroxide-in-adolescents-a-12-month-follow-up
#17
RANDOMIZED CONTROLLED TRIAL
Marcelo Mendes Pinto, Marcela Leticia Leal Gonçalves, Ana Carolina Costa da Mota, Alessandro Melo Deana, Silvia Regina Olivan, Carolina Bortoletto, Camila Haddad Leal de Godoy, Katia Lumi Tanikawa Vergilio, Olga Maria Altavista, Lara J Motta, Sandra Kalil Bussadori
OBJECTIVES: To evaluate the colorimetric change in incisors and canines of adolescents aged 12 to 20 years submitted to at-home whitening and to evaluate satisfaction, sensitivity and discomfort during the procedures through a questionnaire. METHOD: Thirty adolescents were randomly assigned to the following groups: 1) 6.0% hydrogen peroxide (White Class with calcium - FGM); 2) 7.5% hydrogen peroxide (White Class with calcium - FGM); 3) 10% hydrogen peroxide (Oral B 3D White - Oral-B); 4) Control group - placebo...
March 2017: Clinics
https://www.readbyqxmd.com/read/28299466/development-of-oral-cancer-vaccine-using-recombinant-bifidobacterium-displaying-wilms-tumor-1-protein
#18
Koichi Kitagawa, Tsugumi Oda, Hiroki Saito, Ayame Araki, Reina Gonoi, Katsumi Shigemura, Yoshiko Hashii, Takane Katayama, Masato Fujisawa, Toshiro Shirakawa
Several types of vaccine-delivering tumor-associated antigens (TAAs) have been developed in basic and clinical research. Wilms' tumor 1 (WT1), identified as a gene responsible for pediatric renal neoplasm, is one of the most promising TAA for cancer immunotherapy. Peptide and dendritic cell-based WT1 cancer vaccines showed some therapeutic efficacy in clinical and pre-clinical studies but as yet no oral WT1 vaccine can be administrated in a simple and easy way. In the present study, we constructed a novel oral cancer vaccine using a recombinant Bifidobacterium longum displaying WT1 protein...
June 2017: Cancer Immunology, Immunotherapy: CII
https://www.readbyqxmd.com/read/28222156/toothbrush-abrasivity-in-a-long-term-simulation-on-human-dentin-depends-on-brushing-mode-and-bristle-arrangement
#19
Mozhgan Bizhang, Ilka Schmidt, Yong-Hee Patricia Chun, Wolfgang H Arnold, Stefan Zimmer
OBJECTIVE: The aim of this study was to evaluate the susceptibility of dentin to brushing abrasion using four different toothbrushes (rotating-oscillating, sonic and two types of manual toothbrushes) with the same brushing forces. METHODS: Dentin samples (n = 72) were selected from 72 impacted third molars. Half of the surface of dentin samples was covered with an adhesive tape, creating a protected and a freely exposed area in the same specimen. Brushing was performed with either a: sonic (Sonicare PowerUp, Philips GmbH, Hamburg, Germany), b: oscillating-rotating (Oral B Vitality Precisions Clean, Procter & Gamble, Schwalbach am Taunus, Germany) or two different manual toothbrushes c: flat trim brush head toothbrush (Dr...
2017: PloS One
https://www.readbyqxmd.com/read/28178640/a-phase-i-ii-study-of-the-investigational-drug-alisertib-in-combination-with-abiraterone-and-prednisone-for-patients-with-metastatic-castration-resistant-prostate-cancer-progressing-on-abiraterone
#20
Jianqing Lin, Sheel A Patel, Ashwin R Sama, Jean H Hoffman-Censits, Brooke Kennedy, Deborah Kilpatrick, Zhong Ye, Hushan Yang, Zhaomei Mu, Benjamin Leiby, Nancy Lewis, Massimo Cristofanilli, William Kevin Kelly
LESSONS LEARNED: Patients with metastatic castration-resistant prostate cancer did not tolerate the combination of alisertib with abiraterone and prednisone.There was no clear signal indicating that adding alisertib might be beneficial for those patients progressing on abiraterone. BACKGROUND: We hypothesized that Aurora A kinase (AK) contributes to castrate resistance in prostate cancer (PCa) and that inhibiting AK with alisertib can resensitize PCa cells to androgen receptor (AR) inhibitor abiraterone...
November 2016: Oncologist
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