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https://www.readbyqxmd.com/read/29738326/does-preoperative-enteral-or-parenteral-nutrition-reduce-postoperative-complications-in-crohn-s-disease-patients-a-meta-analysis
#1
Gregory T Brennan, Iris Ha, Christopher Hogan, Emily Nguyen, M M Jamal, Matthew L Bechtold, Douglas L Nguyen
OBJECTIVES: Crohn's disease (CD) patients frequently develop complications that require surgery for management. The high prevalence of malnutrition in CD patients presents a challenge because poor preoperative nutritional status has been shown to increase postoperative complications. In this study, we assessed whether preoperative enteral nutrition (EN) or total parenteral nutrition (TPN) decreases postoperative complications in CD patients. MATERIALS AND METHODS: A three-point systematic and comprehensive literature search was carried out on multiple databases followed by a meta-analysis with results presented as odds ratio (OR) using two models, the Mantel-Haenszel model and the DerSimonian and Laird model...
May 7, 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29725969/differences-in-glycemic-control-in-diabetic-and-non-diabetic-patients-with-parenteral-nutrition-using-a-basal-plus-correction-insulin-regimen-an-observational-retrospective-study
#2
Analía Ramos, Fernanda Rabasa, Lilian Mendoza, Joana Cardenete, Pedro Gill, Alba Morilla, Daniel Cardona, Antonio Pérez
INTRODUCTION: Hyperglycemia is a frequent complication of parenteral nutrition (PN) in patients both with and without diabetes mellitis (DM). The aim of this study was to evaluate the quality of glucose control achieved with basal plus-correction insulin in surgical patients with and without a history of DM receiving PN. METHODS: Retrospective evaluation of a protocol applied during the period of January 2013-December 2015. The insulin dose was started at 0.4 and 0...
May 3, 2018: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://www.readbyqxmd.com/read/29715193/severe-lactic-acidosis-in-an-extremely-low-birth-weight-infant-due-to-thiamine-deficiency
#3
Hulya Ozdemir, Hulya Bilgen, Zeynep Alp Unkar, Ertugrul Kiykim, Asli Memisoglu, Eren Ozek
BACKGROUND: In this case report, we present a preterm newborn with persistent lactic acidosis who received total parenteral nutrition (TPN) that lacked thiamine. CASE PRESENTATION: A 28-week-old, 750 g female infant was born with an Apgar score of 8 at the 5th minute. Umbilical cord blood gas levels, including lactate level, were normal, and she was admitted to our neonatal intensive care unit (NICU). Achieving full enteral feeding was not possible due to gastric residues and abdominal distention, making the patient dependent on TPN during the first 2 weeks of life...
May 1, 2018: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/29689743/extravasation-of-total-parenteral-nutrition-into-the-liver-from-an-upper-extremity-peripherally-inserted-central-venous-catheter
#4
Arpit Gupta, Alok Bhutada, Miheret Yitayew, Shantanu Rastogi
Peripherally inserted central catheters (PICC) are the mainstay of central venous access in preterm infants, and one of the common procedures performed in neonatal intensive care unit (NICU). Complications of PICC include infection, mechanical dysfunction, thrombosis, migration, and extravasation of the infusate. In this report, we describe a case of PICC inserted from an upper extremity with migration into the inferior vena cava (IVC) and the hepatic vein associated with extravasation of the total parenteral nutrition (TPN) into the peritoneum and the liver...
2018: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/29689738/factors-associated-with-long-term-mechanical-ventilation-in-extremely-preterm-infants
#5
Lina Yossef, Edward G Shepherd, Susan Lynch, Kristina M Reber, Leif D Nelin
BACKGROUND: The objective of this study was to determine factors associated with long-term intermittent positive pressure ventilation (IPPV) in extremely preterm infants. METHODS: Study setting was a ten bed pod (SBP) part of the Level IV all referral NICU, dedicated to the care of infants born at <27 weeks and which utilizes a protocol-driven approach to care. All admissions to the SBP from 2005 to 2011 were included if admitted in the first week of life and alive at 56 days of age...
2018: Journal of Neonatal-perinatal Medicine
https://www.readbyqxmd.com/read/29686552/myocardial-ischemia-in-an-adolescent-secondary-to-nutritional-thiamine-deficiency
#6
Cassandra Lefevre, Lea H Mallett, Lori Wick
Thiamine (vitamin B1) is an essential vitamin found in most food products in developed nations. Deficiencies in this crucial vitamin lead to diseases related to nutritional needs, metabolic demands, enzymatic function, and neurological inflammation. We present an 18-year-old patient with a history of nasopharyngeal carcinoma and total parenteral nutrition (TPN) dependence who experienced neurological manifestations and heart failure, likely due to underlying thiamine deficiency, dehydration, and vasodilation...
January 2018: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/29686548/evaluating-predictors-of-invasive-candidiasis-in-patients-with-and-without-candidemia-on-micafungin
#7
Amy Carr, Peter Colley, Mezgebe Berhe, Hoa L Nguyen
Numerous risk factors have been linked to invasive candidiasis; however, they are nonspecific and often trigger empiric antifungal therapy in a large number of patients. Identification of more precise predictors could promote judicious use of empiric echinocandins. In this retrospective review, 127 patients with blood cultures positive for Candida spp. were compared to a randomly selected cohort of 134 patients on empiric micafungin for ≥3 days and with blood cultures negative for Candida spp. Factors associated with candidemia included total parenteral nutrition (TPN; 26...
January 2018: Proceedings of the Baylor University Medical Center
https://www.readbyqxmd.com/read/29682387/surgical-management-of-encapsulating-peritoneal-sclerosis-a-case-report-in-kidney-transplant-patient
#8
R Shahbazov, M Talanian, J L Alejo, F Azari, A Agarwal, K L Brayman
Introduction: Encapsulating peritoneal sclerosis (EPS) is a clinical syndrome of progressive fibrotic change in response to prolonged, repetitive, and typically severe insult to the peritoneal mesothelium, often occurring in the setting of peritoneal dialysis (PD). Clear guidelines for successful management remain elusive. We describe the successful surgical management of EPS in a 28-year-old male s/p deceased donor kidney transplant for end-stage renal disease (ESRD) secondary to focal segmental glomerulosclerosis (FSGS)...
2018: Case Reports in Surgery
https://www.readbyqxmd.com/read/29666098/a-misplaced-peripherally-inserted-central-catheter-presenting-as-contralateral-pleural-effusion
#9
Jogender Kumar, Sudeep K C, Kanya Mukhopadhyay, Somosri Ray
A preterm neonate born at 27 weeks, with a birth weight of 555 g, was on continuous positive airway pressure (CPAP) for apnoea of prematurity and initially received total parenteral nutrition (TPN) through the umbilical venous catheter. Peripherally inserted central catheter (PICC) was inserted in the left basilica vein on day 8 to continue TPN. The baby developed respiratory distress with persistent hypoxia after TPN was initiated through the PICC line. The baby required mechanical ventilation due to worsening of respiratory distress, and chest X-ray, as well as ultrasound conducted 12 hours, postinfusion of TPN revealed right-sided pleural effusion...
April 17, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29656269/task-positive-and-task-negative-networks-in-major-depressive-disorder-a-combined-fmri-and-eeg-study
#10
Gennady G Knyazev, Alexander N Savostyanov, Andrey V Bocharov, Ivan V Brak, Evgeny A Osipov, Elena A Filimonova, Alexander E Saprigyn, Lyubomir I Aftanas
BACKGROUND: The study of intrinsic connectivity networks, i.e., sets of brain regions that show a high degree of interconnectedness even in the absence of a task, showed that major depressive disorder (MDD) patients demonstrate an increased connectivity within the default mode network (DMN), which is active in a resting state and is implicated in self-referential processing, and a decreased connectivity in task-positive networks (TPNs), which increase their activity in attention tasks...
April 7, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29614806/prediction-of-renal-acid-load-in-adult-patients-on-parenteral-nutrition
#11
Roberto Iacone, Clelia Scanzano, Anna D'Isanto, Andrea Vitalone, Ignazio Frangipane, Mariana D'Angeli, Lidia Santarpia, Franco Contaldo
Metabolic acidosis and metabolic bone disease are frequent complications in patients on parenteral nutrition (PN). A common contributor to these complications could be a daily high renal acid load. This study aims to find a method for predicting the potential total acid load (PTAL) and the pH of the compounded parenteral nutrition mixtures. The pH and titratable acidity (TA) of fifty compounded mixtures were measured. The potential metabolic acid load (PMAL) was calculated by considering the amount of nutrients that are acid producers and consumers...
April 2, 2018: Pharmaceutics
https://www.readbyqxmd.com/read/29605266/gastrointestinal-mucosal-development-and-injury-in-premature-lambs-supported-by-the-artificial-placenta
#12
Jennifer S McLeod, Joseph T Church, Prathusha Yerramilli, Megan A Coughlin, Elena M Perkins, Raja Rabah, Robert H Bartlett, Alvaro Rojas-Pena, Joel K Greenson, Erin E Perrone, George B Mychaliska
BACKGROUND: An Artificial Placenta (AP) utilizing extracorporeal life support (ECLS) could revolutionize care of extremely premature newborns, but its effects on gastrointestinal morphology and injury need investigation. METHODS: Lambs (116-121days GA, term=145; n=5) were delivered by C-section, cannulated for ECLS, had total parenteral nutrition (TPN) provided, and were supported for 7days before euthanasia. Early and Late Tissue Controls (ETC, n=5 and LTC, n=5) delivered at 115-121days and 125-131days, respectively, were immediately sacrificed...
March 8, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29603815/the-relationship-of-delirium-and-risk-factors-in-cardiology-intensive-care-unit-patients-with-the-nursing-workload
#13
A Öztürk Birge, T Bedük
AIMS AND OBJECTIVES: The aim of the study is to evaluate the relationship of delirium and risk factors in cardiology intensive care unit (ICU) patients with the nursing workload. BACKGROUND: Delirium is a common syndrome in patients with cardiac problems. The risk factors causing delirium and the presence and type of delirium affect the nurse workload and patient care quality adversely. DESIGN: This cross-sectional study was conducted with 133 patients staying at the cardiology ICU of a university hospital between January 5 and March 31, 2017...
March 31, 2018: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/29594085/stress-signals-during-sucking-activity-are-associated-with-longer-transition-time-to-full-oral-feeding-in-premature-infants
#14
You Gyoung Yi, Byung-Mo Oh, Seung Han Shin, Jin Yong Shin, Ee-Kyung Kim, Hyung-Ik Shin
Several treatments have been proposed to shorten the time to the attainment of full oral feeding (FOF) for premature infants, but there are only a few evaluation methods useful in estimating predictors of this period. We investigated whether specific items within the disorganized sucking patterns described by the Neonatal Oral-Motor Assessment Scale (NOMAS) could estimate the time to FOF in preterm infants with feeding difficulty. Preterm infants diagnosed with a disorganized sucking pattern in the NOMAS evaluation before 50 weeks of postmenstrual age were included...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29567321/effect-of-early-fasting-and-total-parenteral-nutrition-support-on-the-healing-of-incision-and-nutritional-status-in-patients-after-sacrectomy
#15
S Gao, Y Zheng, X Liu, Z Tian, Y Zhao
INTRODUCTION: Surgical site infection is one of the most common complications for patients after sacrectomy which often accompanied by poor wound healing, sinus formation and serious metabolic disturbance. HYPOTHESIS: We tried to avoid the surgical site infection caused by feces during early period after surgery through early fasting and total parenteral nutrition(TPN) support, then compared the clinical results of these patients with other patients that received enteral nutrition (EN) early after sacrectomy...
March 19, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29555318/blood-gas-sample-spiking-with-total-parenteral-nutrition-lipid-emulsion-and-concentrated-dextrose-solutions-as-a-model-for-predicting-sample-contamination-based-on-glucose-result
#16
Jose C Jara-Aguirre, Steven W Smeets, Amy M Wockenfus, Brad S Karon
OBJECTIVE: Evaluate the effects of blood gas sample contamination with total parenteral nutrition (TPN)/lipid emulsion and dextrose 50% (D50) solutions on blood gas and electrolyte measurement; and determine whether glucose concentration can predict blood gas sample contamination with TPN/lipid emulsion or D50. DESIGN AND METHODS: Residual lithium heparin arterial blood gas samples were spiked with TPN/lipid emulsion (0 to 15%) and D50 solutions (0 to 2.5%). Blood gas (pH, pCO2, pO2), electrolytes (Na+, K+ ionized calcium) and hemoglobin were measured with a Radiometer ABL90...
March 16, 2018: Clinical Biochemistry
https://www.readbyqxmd.com/read/29550558/bioaugmentation-of-chlorothalonil-contaminated-soil-with-hydrolytically-or-reductively-dehalogenating-strain-and-its-effect-on-soil-microbial-community
#17
Xi-Hui Xu, Xiao-Mei Liu, Long Zhang, Yang Mu, Xu-Yuan Zhu, Jing-Ya Fang, Shun-Peng Li, Jian-Dong Jiang
Although bioaugmentation of pollutant-contaminated sites is a great concern, there are few reports on the relationships among indigenous microbial consortia, exogenous inocula, and pollutants in a bioaugmentation process. In this study, bioaugmentation with Pseudochrobactrum sp. BSQ1 and Massilia sp. BLM18, which can hydrolytically and reductively dehalogenate chlorothalonil (TPN), respectively, was studied for its ability to remove TPN from soil; the alteration of the soil microbial community during the bioaugmentation process was investigated...
March 8, 2018: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/29550034/overfeeding-associated-hyperglycemia-and-injury-response-homeostasis-in-critically-ill-neonates
#18
Tina Tian, Joshua Coons, Hong Chang, Walter J Chwals
BACKGROUND: Injury severity induces a proportionate acute metabolic stress response, associated with increased risk of hyperglycemia. We hypothesized that excess caloric delivery (overfeeding) during high stress states would increase hyperglycemia and disrupt response homeostasis. METHODS: Gestational age, daily weight, total daily caloric intake, serum C-reactive protein (CRP), prealbumin, and blood glucose concentrations in all acutely-injured premature NICU infants requiring TPN over the past 3years were reviewed...
December 27, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29530743/epidemiology-risk-factors-and-outcomes-of-multi-drug-resistant-bloodstream-infections-in-hematopoietic-stem-cell-transplant-recipients-importance-of-previous-gut-colonisation
#19
Aliana Meneses Ferreira, Frederico Moreira, Thais Guimaraes, Fernanda Spadão, Jessica Fernandes Ramos, Marjorie Vieira Batista, Jayr Schmidt Filho, Silvia Figueiredo Costa, Vanderson Rocha
BACKGROUND: Bloodstream infections (BSI) are a major complication in the early phase of a hematopoietic stem cell transplant (HSCT). AIM: To describe the incidence and risk factors for BSI occurring in the pre-engraftment phase of HSCT and its impact on mortality. METHODS: We retrospectively analysed clinical variables of 232 HSCT patients between 2014 and 2015. Univariate Cox regression analyses were performed to test the association between each covariate and the outcome...
March 9, 2018: Journal of Hospital Infection
https://www.readbyqxmd.com/read/29525273/appropriate-use-of-total-parenteral-nutrition-in-children-with-perforated-appendicitis
#20
Yasmine Yousef, Fouad Youssef, Michael Homsy, Trish Dinh, Hayden Stagg, Robin Petroze, Robert Baird, Jean-Martin Larberge, Dan Poenaru, Pramod Puligandla, Kenneth Shaw, Sherif Emil
BACKGROUND: Total parenteral nutrition (TPN) is often used in children with perforated appendicitis, despite the absence of clear indications. We assessed the validity of specific clinical indications for initiation of TPN in this patient cohort. METHODS: Data were gathered prospectively on duration of nil per os (NPO) status and TPN use in a cohort of children treated under a perforated appendicitis protocol during a 19-month period. TPN was started in the immediate postoperative period in patients who had generalized peritonitis and severe intestinal dilatation at operation, or later per the discretion of the attending surgeon...
May 2018: Journal of Pediatric Surgery
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