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Cerebral hemorrage

Feng Li, Jing Yang, Xiaoyan Guo, Xiaomei Zheng, Zhiyu Lv, Chang Qing Shi, Xiaogang Li
OBJECTIVE: To investigate the changes of Apo-J and Omi/HtrA2 protein expression in rats with intracerebral hemorrage. METHODS: 150 SD adult rats were randomly divided into 3 groups: (1) Normal Control (NC) group, (2) Sham group, (3) Intracerebral Hemorrage (ICH) group. The data were collected at 6h, 12h, 1d, 2d, 3d, 5d and 7d. Apoptosis was measured by Tunel staining. The distributions of the Apo-J and Omi/HtrA2 proteins were determined by immunohistochemical staining...
March 23, 2018: World Neurosurgery
Davide Nasi, Franco Servadei, Antonio Romano
We report a case in which common radiologic images masked a rare case of supratentorial hemangioblastoma (HBL). Other peculiarities of this case are the clinical presentation with status epilepticus and the occurrence of a supratentorial HBL unrelated to von Hippel-Lindau syndrome. Based on clinical and radiologic findings, including massive cerebral edema and hemorrhagic presentation, our preoperative diagnosis was a cerebral metastasis. In this scenario, physicians must take into account the words of the Roman fabulist Phaedrus: "Non semper ea sunt, quae videntur, decipit frons prima multos" (things are not always what they seem; the first appearance deceives many)...
August 2017: World Neurosurgery
Danilo Toni, Alessio Pieroni
Neuroimaging has a key role in the assessment and treatment of acute stroke. Cerebral computer tomography is the first step to differentiate hemorragic from ischemic stroke and to detect, in the latter, early signs representative of the lesion severity and predicting a possible hemorrhagic infarction after thrombolytic treatment.Advanced neuroimaging techniques are relevant in the assessment of the ischemic and/or hypo-perfused area, being an essential tool in uncertain situations or when the time of symptoms onset is unavailable, increasing the efficacy and safety of endovenous thrombolysis by enlarging its therapeutic window and leading to more accurate selection of patients to be treated...
January 2017: Journal of Cardiovascular Medicine
Xianling Wang, Yanhui Yang, Xiangbo Wang, Cunjiang Li
OBJECTIVE: To explore the clinical and radiological features of bilateral thalamus venous infarction. METHODS: The cases definitely diagnosed as thalamus venous infarction were collected and the corresponding clinical and radiological data were retrospectively analyzed. RESULTS: Four cases confirmed as thalamus venous infarction by digital substraction angiography (DSA) were collected. Bilateral thalamus lesions were detected in all cases by brain MRI scans which mainly presented as thalamus edema with high T1 and T2 signals with partial enhancement...
August 2014: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
E R Gasenzer, E A M Neugebauer
The composer Felix Mendelssohn-Bartholdy and his sister, Fanny Hensel, both died in 1847 of intracerebral hemorrhage. Also their father and grandfather had died of cerebral strokes. Their cases show the dramatic progress of an arteriovenous malformation in the nineteenth century, but also the development of new romantic styles in the history of western music. Since the late nineteenth and the early twentieth century, neurology and neurosurgery had developed as highly specialized medical subjects. Today, neurosurgery is a highly developed medical subject, and the neurosurgeon uses high-tech equipment for neurosurgical procedures and intensive care...
May 2014: Acta Neurochirurgica
Blaine L Hart, Saeid Taheri, Gary A Rosenberg, Leslie A Morrison
The aim of this study is to quantitatively evaluate the behavior of CNS cavernous malformations (CCMs) using a dynamic contrast-enhanced MRI (DCEMRI) technique sensitive for slow transfer rates of gadolinium. The prospective study was approved by the institutional review board and was HIPPA compliant. Written informed consent was obtained from 14 subjects with familial CCMs (4 men and 10 women, ages 22-76 years, mean 48.1 years). Following routine anatomic MRI of the brain, DCEMRI was performed for six slices, using T1 mapping with partial inversion recovery (TAPIR) to calculate T1 values, following administration of 0...
October 2013: Translational Stroke Research
Youn Hyuk Chang, Sung-Kyun Hwang
We report an unusual case of cerebral aneurysmal subarachnoid hemorrage (SAH) with Fabry's disease. A 42-year-old woman presented with aneurysmal SAH originated from a saccular aneurysm of the right posterior communicating artery. The patient was treated by an endovascular coil embolization of aneurysm. Postoperatively the patient recovered favorably without any neurological deficit. During her admission, the patient had a sign of proteinuria in urine analysis. The pathologic findings of kidney needle biopsy implied nephrosialidosis (mucolipidosis of lysosomal stroage disease), which is consistent with a Fabry's disease...
March 2013: Journal of Korean Neurosurgical Society
F Apostoae, Liliana Tarţău, Diana Cimpoeşu, Cătălina Elena Lupuşoru
AIM: To evaluate drugs interactions with oral anticoagulants and their clinical relevance, in patients from two emergency departments in hospital. MATERIAL AND METHODS: Retrospective study, during one year, on patients (between 18 and 85 year old) with haemostatic disturbances admitted at two emergency departments in ,,Sf. Spiridon" Hospital, Iaşi and in Piatra Neamţ Public Hospital, consisted in medical records analysis: the diagnostic, therapy recommended. Data were scored and statistically analyzed by t test (Windows Excel)...
October 2011: Revista Medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti Din Iaş̧i
M Cohen, B Baldin, P Thomas, C Lebrun
INTRODUCTION: Anti-TNF alpha treatments are increasingly prescribed in various rheumatological or gastroenterological inflammatory diseases. Several adverse events, including neurological episodes have been reported in the literature. Relation to treatment is a major concern and guidelines for management of those patients are not available. The aim of our study is to collect and analyze neurological adverse events occurring during anti-TNF alpha therapy, and to propose guidelines for diagnosis of demyelinating-induced diseases...
January 2012: Revue Neurologique
Emilie Guillard, Bénédicte Nancy, Hervé Floch, Anne Henckes, Guy Cochard, Josiane Arvieux, Charles Christian Arvieux
Iatrogenic gas embolism is a rare but serious problem that has been documented in almost all medical specialties including gynecology. We present a 49-year-old woman undergoing operative hysteroscopy and myomectomy, who sustained sudden hypotension and decrease in the end-tidal carbon dioxid levels during the procedure. Systemic gas embolism was confirmed by echocardiographic evidence of bubbles in both right and left cardiac cavities and a rise of troponin. Hyperbaric oxygen was rapidly administered in addition to maintenance of vital functions and anti-thrombotic prevention with calciparin...
March 2010: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
Carlos Augusto Ferreira Lobão, Janio Nogueira, Antonio Aversa Dutra do Souto, José Antonio de Oliveira
Treatment of intracranial tumoral lesions is related to its correct histological diagnostic. We present a retrospective analysis of 32 patients submitted to 36 cerebral biopsies using neuronavigation and 44 patients using frame-based stereotaxy. Mean age was 46.6 and 49.3 years old respectively. Sex distribution in both groups was 50% for each. Most of lesions were lobar in both groups. Diagnostic yielding was 91.7% and 83.4%, respectively (p=0.26). We found in the postoperative CT scans intracranial hemorrhages in 13...
September 2009: Arquivos de Neuro-psiquiatria
M Milicevic, J M Krzesinski
The relationships between the brain and arterial hypertension are strong. The brain, through the hypothalamus, can quickly adapt the blood pressure level to maintain the cerebral blood flow. An acute increase in blood pressure, if it overtakes the autoregulatory capacities, needs an urgent intervention to decrease neurological problems such as encephalopathy. In chronic situations, arterial hypertension is a frequent cause of stroke, either ischemic or hemorragic, both in patients free and those who have already suffered from brain damage...
May 2008: Revue Médicale de Liège
Fabienne Ory-Magne, Christine Brefel-Courbon, Marion Simonetta-Moreau, Nelly Fabre, Jean Albert Lotterie, Patrick Chaynes, Isabelle Berry, Yves Lazorthes, Olivier Rascol
We sought to define the influence of ageing in clinical, cognitive, and quality-of-life outcomes after subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson's disease (PD). We performed motor assessment (UPDRS), mood tests, cognitive, and quality of life evaluation (PDQ-39) on PD patients before surgery, and 12 and 24 months after, and we recorded adverse events. The variations of these parameters after surgery were correlated with age using regression statistical tests. Cerebral bleeding risk was evaluated by a nonparametric test...
July 30, 2007: Movement Disorders: Official Journal of the Movement Disorder Society
Yan Liu, Xiao-yan Ke, Jun Ma, Zhi-xiang Shen, Xiao-hong Zhang, Xin Du, Yi-ming Zhao, Jing-qiao Lv, Zhao-min Zhan, Xiao-ying Zeng, Xiao-hua Xu, Ze-sheng Lu
OBJECTIVE: To evaluate the safety of domestically produced idarubicin in the treatment of acute leukemia by a multicenter randomized control trial. METHODS: This trial was carried out in the hemotologica department of five hospitals throughout China, with hospitalized patients who suffered from acute myelogenous leukemia ( AML except M3 type) , acute lymphocytic leukemia ( ALL) , chronic myelogenous leukemia-blast (CML-blast) , totally 155 patients. Those with severely cardial, hepatic or renal disfunction or those who had ever treated with > or = 200 mg/m(2) idarubicin were excluded from the trial...
September 2006: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
Philippa Lavallée
Stroke patients are at very high risk of recurrent vascular events. Antiplatelet agents (AAP) substantially decrease this risk but still 1 over 5 patients will have an other vascular event. Recent studies didn't show any benefit of AAP association (aspirin, clopidogrel) but other studies targetting higher risk patients are needed. Studies with new AAP are ongoing. Beside vascular risk reduction, other antithrombotic agents are used as thrombolytics in the acute phase of stroke. The rt-PA (recombinant tissue plasminogen activator) administered in the first 3 hours dissolves the clot, preventing death and handicap due to ischemic brain lesion...
September 2006: Thérapie
Elisa Boscolo, Giacomo Pavesi, Paolo Zampieri, Maria Teresa Conconi, Chiara Calore, Renato Scienza, Pier Paolo Parnigotto, Marcella Folin
Cerebral aneurysms and arteriovenous malformations (AVM) are a common cause of stroke and cerebral hemorrage. Both are often discovered when they rupture, causing subarachnoid hemorrhage (SAH). SAH-induced vasospasm is mediated by enhanced vasoconstriction due to endothelin-1 (ET-1). We investigated whether endothelial cells (ECs) obtained from aneurysm and AVM express phenotypic and genotypic alterations contributing to the development of vasospasm after SAH. We isolated ECs from human AVM and aneurysm and then confirmed their EC origin by polymerase chain reaction and immunocytochemistry with endothelial markers...
November 2006: International Journal of Molecular Medicine
Sh Sh Nurmatov, N S Nurmatova
An effect of nitrogen oxide donator Nebilet and inhibitor of NO-synthase L-Name in concentration 10(-4) and 10(-5) on some biochemical indices in vitro has been studied. It was established that an incubation of tissues with nitrogen oxide donator results in an increase of nitrits' level, some intensification of LPO and activation of antioxidant defense enzymes, especially in rats with SAH. On the contrary, an incubation of cerebral homogenate with inhibitor of NO-synthase L-NAME resulted in considerable lowering of nitrits' level, significant activation of LPO...
January 2006: Likars'ka Sprava
P Leclercq, A Thomas, B Sadzot
Rendu-Osler disease or hereditary hemorragic telangiectasia is a group of autosomal dominant diseases characterized by angiodysplasic lesions in the skin, mucous membranes and viscera with risks of recurrent bleedings. Neurological complications have been described in 10-30% of these patients, most often hemorrhagic or septic. More exceptionally, ischemic strokes occur in these patients, particularly if they have pulmonary arteriovenous malformations. We report the observation of a 25 year old man who developed a latero-protuberantial stroke...
July 2005: Revue Médicale de Liège
I D Stulin, S V Tsarenko, O V Levchenko
An original method of impedancemetry designed by the authors and applied in 88 cases of cerebral edema caused by brain aneurysm rupture (n = 23), by acute hemorragic stroke of hypertensive type (n = 13) and craniocerebral injury (n = 52) is described. Diagnostic value of the method, its safety and convenience for clinical practice are demonstrated.
2005: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
Takashi Yamanaka, Masayuki Ishii, Hiroko Suzuki
OBJECTIVE: We looked for the patients who were treated by short leg brace (SLB) in our hospital for the effects on the treatment of stroke. METHOD: Patients admitted to our hospital for the purposes of rehabilitation of stroke and had SLB prescription from October 2001 to October 2003 were investigated. A total of 20 patients (19 men, 11 women) were investigated in this study. Average age was 60.8 +/- 8.60 years old. Diagnoses were cerebral hemorrhage (12), brain infarction (7), and subarachnoid hemorrage (2)...
2004: Topics in Stroke Rehabilitation
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