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https://www.readbyqxmd.com/read/29344620/association-of-depression-with-mortality-in-older-adults-undergoing-transcatheter-or-surgical-aortic-valve-replacement
#1
Laura M Drudi, Matthew Ades, Sena Turkdogan, Caroline Huynh, Sandra Lauck, John G Webb, Nicolo Piazza, Giuseppe Martucci, Yves Langlois, Louis P Perrault, Anita W Asgar, Marino Labinaz, Andre Lamy, Nicolas Noiseux, Mark D Peterson, Rakesh C Arora, Brian R Lindman, Melissa Bendayan, Rita Mancini, Amanda Trnkus, Dae H Kim, Jeffrey J Popma, Jonathan Afilalo
Importance: Depression is increasingly recognized as a risk factor for adverse outcomes in cardiovascular disease. However, little is known about depression in older adults undergoing transcatheter (TAVR) or surgical (SAVR) aortic valve replacement. Objective: To determine the prevalence of depression and its association with all-cause mortality in older adults undergoing TAVR or SAVR. Design, Setting, and Participants: This preplanned analysis of the Frailty Aortic Valve Replacement (FRAILTY-AVR) prospective cohort study included 14 centers in 3 countries from November 15, 2011, through April 7, 2016...
January 17, 2018: JAMA Cardiology
https://www.readbyqxmd.com/read/29327563/hemodynamic-outcomes-of-the-ross-procedure-versus-other-aortic-valve-replacement-a-systematic-review-and-meta-analysis
#2
Kevin J Um, Graham R McCLURE, Emilie P Belley-Cote, Saurabh Gupta, Ismail Bouhout, Hugo Lortie, Hatim Alraddadi, Ali Alsagheir, Matthias Bossard, William F McINTYRE, Alexandra Lengyel, John W Eikelboom, Maral Ouzounian, Michael W Chu, Dominic Parry, Ismail El-Hamamsy, Richard P Whitlock
INTRODUCTION: Life expectancy in young adults undergoing mechanical or bioprosthetic aortic valve replacement (AVR) may be reduced by up to 20 years compared to age matched controls. The Ross procedure is a durable, anticoagulation-sparing alternative. We performed a systematic review and meta-analysis to compare the valve hemodynamics of the Ross procedure versus other AVR. EVIDENCE ACQUISITION: We searched Cochrane CENTRAL, MEDLINE and EMBASE from inception to February 2017 for randomized controlled trials (RCTs) and observational studies (n≥10 Ross)...
January 9, 2018: Journal of Cardiovascular Surgery
https://www.readbyqxmd.com/read/29326128/idiopathic-ventricular-arrhythmias-originating-from-the-vicinity-of-the-communicating-vein-of-cardiac-venous-systems-at-the-left-ventricular-summit
#3
Yuki Komatsu, Akihiko Nogami, Yasutoshi Shinoda, Keita Masuda, Takeshi Machino, Kenji Kuroki, Hiro Yamasaki, Yukio Sekiguchi, Kazutaka Aonuma
BACKGROUND: The communicating vein (CV) between the great cardiac vein and small cardiac venous systems passes between the aortic and pulmonary annulus and is located in close association with the left ventricular summit (summit CV). METHODS AND RESULTS: Thirty-one patients with idiopathic ventricular arrhythmias (VAs) underwent mapping of the left ventricular summit by using a 2F microcatheter introduced into the summit CV with coronary sinus venographic guidance...
January 2018: Circulation. Arrhythmia and Electrophysiology
https://www.readbyqxmd.com/read/29326113/acute-heart-failure-with-new-onset-continuous-murmur-in-a-26-year-old-man
#4
Yi-Chen Wang, Chen-Wei Huang, Ting-Wei Lin
CLINICAL INTRODUCTION: A 26-year-old man with an unremarkable medical history sensed a momentary retrosternal 'pop' followed by overwhelming dyspnoea, without reporting any prodromal symptoms. At the emergency department, he had a significant tachycardia (170 bpm) and an extreme low diastolic blood pressure (<30 mm Hg). A loud, harsh and continuous murmur could be maximally auscultated at the right lower sternal border. ECG revealed global ST depression with ST elevation in lead aVR...
January 11, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29317120/preoperative-invasive-hemodynamic-determinants-of-survival-among-patients-undergoing-aortic-or-mitral-valve-surgery
#5
David X Zhuo, Kenneth C Bilchick, Sula Mazimba
OBJECTIVES: To evaluate the association of preoperative invasive hemodynamic parameters with mortality in valvular heart surgery. DESIGN: Retrospective cohort study. SETTING: Single tertiary academic medical center. PARTICIPANTS: A total of 382 patients who underwent preoperative right and/or left heart catheterization before open aortic valve replacement (AVR), open mitral valve repair/replacement (MVR), or combined AVR and MVR, from July 2009 to December 2014...
September 29, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/29313564/clinical-presentation-surgical-management-and-outcomes-of-patients-treated-for-aortic-stenosis-and-coronary-artery-disease-does-age-matter
#6
Bartłomiej Perek, Veronica Casadei, Mateusz Puślecki, Sebastian Stefaniak, Dawid Maison, Adrian Gwizdała, Anna Perek, Łukasz Szarpak, Marek Jemielity
BACKGROUND: Aortic stenosis and coronary artery disease (CAD) sharing similar risk factors are associated with aging of human population. AIM: The purpose of this study was to examine if age affects clinical presentation, intraoperative management and outcomes of patients that undergo simultaneous operations of aortic valve replacement (AVR) and coronary artery bypass grafting (CABG). METHODS: The study involved 452 consecutive patients with the age of 64...
January 9, 2018: Kardiologia Polska
https://www.readbyqxmd.com/read/29304530/alteration-of-von-willebrand-factor-after-transcatheter-aortic-valve-replacement-in-the-absence-of-paravalvular-regurgitation
#7
Felix Pawlitschek, Cornelius Keyl, Barbara Zieger, Ulrich Budde, Friedhelm Beyersdorf, Franz-Josef Neumann, Christian Stratz, Thomas G Nührenberg, Dietmar Trenk
Moderate or severe paravalvular regurgitation after transcatheter aortic valve implantation (TAVI) is frequently associated with a loss of high-molecular-weight multimers of von Willebrand factor (VWF) and a reduced VWF collagen-binding capacity. It is unclear whether this phenomenon can also be observed in patients with mild paravalvular regurgitation, and whether there are differences between patients undergoing conventional aortic valve replacement (AVR) or TAVI. We analysed the multimeric structure of VWF and the ratio of VWF collagen-binding capacity to VWF antigen pre- and postoperatively in 12 patients scheduled for AVR and in 31 patients scheduled for TAVI...
January 2018: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/29302952/letter-to-the-editor-thrombocytopenia-after-sutureless-aortic-valve-implantation-does-it-really-matter
#8
G Santarpino, F Vogt
Despite the limited clinical relevance of thrombocytopenia after bioprosthetic aortic valve replacement (AVR), the postoperative depletion of platelet count continues to attract the attention of many authors. The development of thrombocytopenia has been evaluated either in patients receiving a sutureless bioprosthesis (1,2) or in those undergoing transcatheter aortic valve implantation, where cardiopulmonary bypass bears little or no relation to this phenomenon (3). Recently, Sánchez et al. (1) have published their findings on this topic, but their limited experience with the devices used makes their study of doubtful interest...
July 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29302941/long-term-outcomes-in-patients-undergoing-consecutive-bioprosthetic-aortic-valve-replacement
#9
Matthew D Haydock, Carissa F Wilkes, Tharumenthiran Ramanathan, David A Haydock
BACKGROUND: Worldwide, there is increased use of bioprosthetic valves in the aortic position. Part of this increase has been patient-driven for quality of life reasons. More recently, bioprosthetic valves have been chosen by progressively younger patients, with a strategy of performing a valve-in-valve TAVI if the prosthesis should wear out. Thus, a review was undertaken of the present authors' experience with patients whose first two aortic valve replacements (AVRs) were with bioprosthetic valves...
July 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29302940/determinants-and-outcome-of-decision-making-among-patients-with-severe-aortic-stenosis
#10
Amjad I Hussain, Andreas Auensen, Cathrine Brunborg, Svend Aakhus, Arnt Fiane, Kjell I Pettersen, Lars Gullestad
BACKGROUND: Aortic valve replacement (AVR) improves survival and quality of life in patients with severe aortic stenosis (AS), but despite clear indications for surgical treatment a significant proportion of patients do not undergo AVR. The study aim was to identify clinical variables associated with the decision to perform AVR, and to assess the prognostic effect of surgery versus medical treatment in patients with severe AS adjusted for significant confounders and effect modifiers. METHODS: A prospective observational study of consenting patients aged >18 years who were under consideration for AVR at the authors' tertiary teaching hospital was conducted...
July 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/29301127/impact-of-preoperative-left-ventricular-remodelling-patterns-on-long-term-outcome-after-aortic-valve-replacement-for-severe-aortic-stenosis
#11
Yohann Bohbot, Dan Rusinaru, Quentin Delpierre, Sylvestre Marechaux, Christophe Tribouilloy
OBJECTIVES: Four patterns of left ventricular (LV) geometry have been described in aortic stenosis (AS): normal geometry, concentric remodelling (LVCR), concentric hypertrophy (CH), and eccentric hypertrophy (EH). LVCR and CH are independently associated with an increased risk of mortality in patients with medically managed AS. No data are available on the impact of aortic valve replacement (AVR) on the negative prognostic implications of LV remodelling patterns. METHODS: This study evaluated the long-term postoperative prognostic value of preoperative LV patterns in a cohort of 779 patients (mean age 73 years) with severe AS and ejection fraction >50% undergoing AVR...
January 5, 2018: Cardiology
https://www.readbyqxmd.com/read/29276909/-management-of-patients-with-isolated-aortic-stenosis-considering-negative-prognostic-factors
#12
I G Nikitin, G E Gendlin, E I Emelina, A I Kovaleva
BACKGROUND: Aortic stenosis (AS) is the most common valve defect in developed countries; its prevalence increases with age of the population. The most frequent cause for isolated AS in adults is calcification of normal tricuspid or congenital bicuspid aortic valve (AV). The only effective treatment of AS is aortic valve replacement (AVR). Major negative prognostic factors include low LV ejection fraction (EF), age older than 70, female gender, and comorbidities such as renal dysfunction, chronic obstructive pulmonary disease, and neural disorders...
2017: Kardiologiia
https://www.readbyqxmd.com/read/29249337/arteriovenous-ratio-and-papilledema-based-hybrid-decision-support-system-for-detection-and-grading-of-hypertensive-retinopathy
#13
Shahzad Akbar, Muhammad Usman Akram, Muhammad Sharif, Anam Tariq, Ubaid Ullah Yasin
BACKGROUND AND OBJECTIVES: Hypertensive Retinopathy (HR) is a retinal disease which happened due to consistent high blood pressure (hypertension). In this paper, an automated system is presented that detects the HR at various stages using arteriovenous ratio and papilledema signs through fundus retinal images. METHODS: The proposed system consists of two modules i.e. vascular analysis for calculation of arteriovenous ratio and optic nerve head (ONH) region analysis for papilledema...
February 2018: Computer Methods and Programs in Biomedicine
https://www.readbyqxmd.com/read/29248286/perioperative-evaluation-of-regional-aortic-wall-shear-stress-patterns-in-patients-undergoing-aortic-valve-and-or-proximal-thoracic-aortic-replacement
#14
Emilie Bollache, Paul W M Fedak, Pim van Ooij, Ozair Rahman, S Chris Malaisrie, Patrick M McCarthy, James C Carr, Alex Powell, Jeremy D Collins, Michael Markl, Alex J Barker
OBJECTIVES: To assess in patients with aortopathy perioperative changes in thoracic aortic wall shear stress (WSS), which is known to affect arterial remodeling, and the effects of specific surgical interventions. METHODS: Presurgical and postsurgical aortic 4D flow MRI were performed in 33 patients with aortopathy (54 ± 14 years; 5 women; sinus of Valsalva (d_SOV)/midascending aortic (d_MAA) diameters = 44 ± 5/45 ± 6 mm) scheduled for aortic valve (AVR) and/or root (ARR) replacement...
November 16, 2017: Journal of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29245315/st-segment-change-and-t-wave-amplitude-ratio-in-lead-avr-associated-with-coronary-artery-disease-severity-in-patients-with-non-st-elevation-myocardial-infarction-a-retrospective-study
#15
Yahya Kemal İçen, Mevlüt Koç
Non-ST elevation myocardial infarction (NSTEMI) severity is difficult only with electrocardiogram (ECG). In most cases, NSTEMI patients are followed with cardiac enzymes without early invasive intervention if no severe chest pain exists in the emergency department (ED) or coronary intensive care unit (CICU).Our aim was to evaluate association between CAD severity and ST segment change in lead aVR (STaVR)/T wave amplitude in lead aVR (TAaVR) ratio in patients with NSTEMI.We included 306 patients with NSTEMI in the ED between 2015 and 2016...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29238100/clinical-outcomes-and-quality-of-life-after-surgery-for-dilated-ascending-aorta-at-the-time-of-aortic-valve-replacement-wrapping-versus-graft-replacement
#16
Tomonobu Abe, Sachie Terazawa, Hideki Ito, Yoshiyuki Tokuda, Kazuro Fujimoto, Masato Mutsuga, Yuji Narita, Hideki Oshima, Akihiko Usui
Wrapping and graft replacement are two optional procedures for the treatment of dilated ascending aorta at the time of aortic valve replacement (AVR). Wrapping is considered less invasive. The aim of this study was to compare the short- and long-term clinical outcomes as well as the long-term quality of life in patients undergoing these two procedures.This study enrolled 40 consecutive patients with dilated ascending aorta who had undergone either wrapping (WAA group, n=20) or replacement (RAA group, n=20) of the ascending aorta at the time of AVR...
November 2017: Nagoya Journal of Medical Science
https://www.readbyqxmd.com/read/29238013/definitive-determinant-of-late-significant-tricuspid-regurgitation-after-aortic-valve-replacement
#17
Shin Yajima, Daisuke Yoshioka, Koichi Toda, Satsuki Fukushima, Shigeru Miyagawa, Yasushi Yoshikawa, Shunsuke Saito, Keitaro Domae, Takayoshi Ueno, Toru Kuratani, Yoshiki Sawa
BACKGROUND: Uncertainties remain regarding the course of existing tricuspid regurgitation (TR) after aortic valve replacement (AVR), and its long-term impact on outcome. We investigated changes in existing TR after isolated AVR for severe aortic stenosis (AS), the impact of preoperative TR on long-term outcome, and predictors of late significant TR.Methods and Results:After excluding mild mitral regurgitation and severe TR, 226 consecutive patients undergoing isolated AVR for severe AS between 2002 and 2015 were reviewed...
December 14, 2017: Circulation Journal: Official Journal of the Japanese Circulation Society
https://www.readbyqxmd.com/read/29237738/ascending-vasa-recta-are-angiopoietin-tie2-dependent-lymphatic-like-vessels
#18
Yael Kenig-Kozlovsky, Rizaldy P Scott, Tuncer Onay, Isabel Anna Carota, Benjamin R Thomson, Hyea Jin Gil, Veronica Ramirez, Shinji Yamaguchi, Christine E Tanna, Stefan Heinen, Christine Wu, Radu V Stan, Janet D Klein, Jeff M Sands, Guillermo Oliver, Susan E Quaggin
Urinary concentrating ability is central to mammalian water balance and depends on a medullary osmotic gradient generated by a countercurrent multiplication mechanism. Medullary hyperosmolarity is protected from washout by countercurrent exchange and efficient removal of interstitial fluid resorbed from the loop of Henle and collecting ducts. In most tissues, lymphatic vessels drain excess interstitial fluid back to the venous circulation. However, the renal medulla is devoid of classic lymphatics. Studies have suggested that the fenestrated ascending vasa recta (AVRs) drain the interstitial fluid in this location, but this function has not been conclusively shown...
December 13, 2017: Journal of the American Society of Nephrology: JASN
https://www.readbyqxmd.com/read/29234970/aortic-valve-reconstruction-using-autologous-pericardium-ozaki-procedure-for-active-infective-endocarditis-a-case-report
#19
Kimiaki Okada, Yoshito Inoue, Hirofumi Haida, Satoru Suzuki
Approximately one-third of patients with infective endocarditis require surgical treatment, but the ideal procedure that prevents infection ensures long durability and maintains quality of life remains unclear. A 21-year-old man who was diagnosed with aortic active infective endocarditis was referred to our hospital for surgical treatment. Echocardiography showed bicuspid aortic valve, severe aortic regurgitation, a large vegetation, and a paravalvular abscess. We planned to perform elective surgical treatment after antibiotic therapy; however, progression to heart failure required urgent operation...
December 12, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29225266/a-case-of-aortic-regurgitation-presenting-with-recurrent-detachment-of-a-prosthetic-valve-as-the-first-presenting-symptom-of-cardiovascular-beh%C3%A3-et-s-disease
#20
Tsugumi Takayama, Takuya Ozawa, Akiko Sanada, Tohru Watanabe, Masahiro Ito, Satoru Hirono, Yoshifusa Aizawa, Tohru Minamino
A 33-year-old man with severe aortic regurgitation underwent initial aortic valve replacement (AVR). During the 2 years after AVR, 3 reoperations for prosthetic valve detachment were required. During hospitalization, he had no typical clinical findings, with the exception of a persistent inflammatory reaction; a pseudo-aneurysm around the Bentall graft developed 27 days after the 4th operation. This unique clinical course suggested the possibility of Behçet's disease. In the 8 years of follow-up after the administration of prednisolone, the pseudo-aneurysm did not become enlarged and the detachment of the prosthetic valve was not observed...
December 8, 2017: Internal Medicine
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