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https://www.readbyqxmd.com/read/29779725/anterior-subtemporal-approach-for-severe-upper-pontine-hematomas-a-report-of-28-surgically-treated-cases
#1
Hong-Tian Zhang, Li-Hua Chen, Miao-Chun Bai, Ru-Xiang Xu
The efficacy and safety of surgery for patients with primary pontine hemorrhage (PPH) remain debatable. Twenty-eight consecutive patients with huge upper PPH were included in this study. They underwent surgical management through a subtemporal approach between January 2009 and October 2013. We analyzed clinical and radiological parameters to assess the patient outcomes. The near-complete (>90%) evacuation rate was 67.9%, and there was no surgery-related death. The overall survival rate at 3 months was 64...
May 17, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29776804/hemicraniectomy-for-malignant-middle-cerebral-artery-syndrome-a-review-of-functional-outcomes-in-two-high-volume-stroke-centers
#2
Abhi Pandhi, Georgios Tsivgoulis, Nitin Goyal, Muhammad F Ishfaq, Shailesh Male, Efstathios Boviatsis, Jason J Chang, Ramin Zand, Konstantinos Voumvourakis, Lucas Elijovich, Anne W Alexandrov, Marc D Malkoff, Daniel Hoit, Adam S Arthur, Andrei V Alexandrov
BACKGROUND AND PURPOSE: Despite recent landmark randomized controlled trials showing significant benefits for hemicraniectomy (HCT) compared with medical therapy (MT) in patients with malignant middle cerebral artery infarction (MMCAI), HCT rates have not substantially increased in the United States. We sought to evaluate early outcomes in patients with MMCAI who were treated with HCT (cases) in comparison to patients treated with MT due to the perception of procedural futility by families (controls)...
May 15, 2018: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29775774/hospital-admissions-2000-2014-a-retrospective-analysis-of-288-096-events-in-patients-with-dementia
#3
Catarina Bernardes, João Massano, Alberto Freitas
INTRODUCTION: Dementia is a leading cause of disability worldwide. It is associated with an increased risk of hospitalization, imposing a significant burden on healthcare systems. The evidence on the long-term evolution of this issue and broadly on healthcare systems is currently limited. This study aims to describe the hospitalizations of people who received a diagnosis of dementia admitted to public general hospitals in a western European country with universal health coverage, over more than a decade...
May 8, 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29772472/postintroduction-study-of-cost-effectiveness-of-pneumococcal-vaccine-pcv10-from-public-sector-payer-s-perspective-in-the-state-of-santa-catarina-brazil
#4
Emil Kupek, Ilse Viertel
OBJECTIVES: To evaluate cost effectiveness of 10-valent pneumococcal conjugate vaccine in the routine immunization program for children younger than 5 years in Brazil by a postintroduction study. METHODS: Ecological study of prevaccine (2006-2009) versus postvaccine (2011-2014) period related the changes in mortality rate and hospitalization rate to direct cost of pneumonia treatment from the payer's perspective to estimate the cost effectiveness regarding lives saved, life-years gained, and disability-adjusted life-year for children younger than 5 years in the southern Brazilian state of Santa Catarina...
May 14, 2018: Value in Health Regional Issues
https://www.readbyqxmd.com/read/29756592/three-year-follow-up-study-in-patients-with-guillain-barr%C3%A3-syndrome
#5
Vesna Martic, Ivo Bozovic, Ivana Berisavac, Ivana Basta, Stojan Peric, Milica Babic, Sonja Lukic Rajic, Bogdan Bjelica, Olivera Stojiljkovic Tamas, Aleksandar Stojanov, Marija Grunauer, Mina Cobeljic, Nenad Komatina, Vanja Djuric, Milutin Petrovic, Balsa Vujovic, Aleksandra Dominovic Kovacevic, Gordana Djordjevic, Dejana Jovanovic, Zorica Stevic
A majority of patients with Guillain-Barré syndrome (GBS) have tendency of a good recovery. Our aim was to evaluate the outcome of the disease 1 and 3 years after GBS symptom onset. METHODS: During 2014, GBS was diagnosed in 82 patients in seven tertiary healthcare centers. Neurological follow-up was conducted in 57 (70%) patients after 1 year, and in 54 (66%) after 3 years. Functional disability was estimated according to the GBS disability scale (GDS), with a score of 0-3 indicating mild disability and a score of 4-6 indicating severe disability during acute phase, whereas a score >1 indicated poor recovery on follow-ups...
May 2018: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://www.readbyqxmd.com/read/29751966/outcomes-in-nursing-home-patients-with-traumatic-brain-injury
#6
Stephanie N Lueckel, Cyrus M Kosar, Joan M Teno, Sean F Monaghan, Daithi S Heffernan, William G Cioffi, Kali S Thomas
BACKGROUND: Traumatic brain injury is a leading cause of death and disability in the United States. In survivors, traumatic brain injury remains a leading contributor to long-term disability and results in many patients being admitted to skilled nursing facilities for postacute care. Despite this very large population of traumatic brain injury patients, very little is known about the long-term outcomes of traumatic brain injury survivors, including rates of discharge to home or risk of death in long-term nursing facilities...
May 9, 2018: Surgery
https://www.readbyqxmd.com/read/29744244/can-amantadine-ameliorate-neurocognitive-functions-after-subarachnoid-haemorrhage-a-preliminary-study
#7
Eren Fatma Akçıl, Özlem Korkmaz Dilmen, Hayriye Vehid, Yusuf Tunalı
Objective: Aneurysmal subarachnoid haemorrhage (SAH) may have devastating effects on patients. Motor and neurocognitive impairments may arise depending on the location and grade of the SAH. Although the effects of amantadine on neurocognitive function after traumatic brain injury have been widely studied to the best of our knowledge, their effects on recovery from SAH in humans have not been studied. The present study aimed to evaluate how amantadine influences improvement in neurocognitive function in patients with aneurysmal SAH over a period of six months...
April 2018: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/29743417/impact-of-indoxyl-sulfate-on-coronary-plaques-in-patients-on-hemodialysis
#8
Masahiko Asami, Kengo Tanabe, Shunsuke Ito, Eri Yoshida, Jiro Aoki, Shuzou Tanimoto, Yu Horiuchi, Masayuki Yoshida
Serum indoxyl sulfate (IS; a uremic toxin) levels, which are significantly higher in patients with chronic kidney disease, including those undergoing hemodialysis, than in the robust, are associated with both cardiovascular disease (CVD) and CVD-related mortality. Furthermore, coronary artery calcium (CAC) is an independent predictor of cardiovascular events in patients undergoing hemodialysis. This study aimed to interpret the association between serum IS levels and coronary plaque burden (CPB) or CAC.A total of 30 consecutive patients on hemodialysis, who underwent 320-row coronary multidetector computed tomography (MDCT) angiography for suspected coronary artery disease, were enrolled in this prospective study...
May 9, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29740921/hospitalization-and-morbidity-due-to-adverse-drug-reactions-in-elderly-patients-a-single-center-study
#9
Silvia Ognibene, Natale Vazzana, Claudio Giumelli, Luisa Savoldi, Luca Braglia, Giuseppe Chesi
BACKGROUND AND AIMS: Adverse drug reaction (ADRs) is a leading but underrecognized cause of illness particularly in frail subjects with multiple comorbidities. We aimed to investigate the frequency, patterns and outcomes of ADRs as a cause of hospitalization in elderly patients admitted to an internal medicine ward. METHODS: We performed a retrospective observational study including every patient aged over 65 years who was admitted to our Department during a 12-month period...
May 9, 2018: Internal Medicine Journal
https://www.readbyqxmd.com/read/29740704/association-of-intensive-care-unit-delirium-with-sleep-disturbance-and-functional-disability-after-critical-illness-an-observational-cohort-study
#10
Marcus T Altman, Melissa P Knauert, Terrence E Murphy, Amy M Ahasic, Zeeshan Chauhan, Margaret A Pisani
BACKGROUND: In medical intensive care unit (MICU) patients, the predictors of post-discharge sleep disturbance and functional disability are poorly understood. ICU delirium is a risk factor with a plausible link to sleep disturbance and disability. This study evaluated the prevalence of self-reported post-ICU sleep disturbance and increased functional disability, and their association with MICU delirium and other ICU factors. METHODS: This was an observational cohort study of MICU patients enrolled in a biorepository and assessed upon MICU admission by demographics, comorbidities, and baseline characteristics...
May 8, 2018: Annals of Intensive Care
https://www.readbyqxmd.com/read/29738278/functional-outcomes-following-post-acute-rehabilitation-for-moderate-to-severe-traumatic-brain-injury
#11
Amy M Rosenbaum, Wayne A Gordon, Antigone Joannou, Brady A Berman
OBJECTIVE: The objective of this study was to examine the benefits of long-term inpatient rehabilitation for individuals with moderate-to-severe traumatic brain injuries (TBIs). METHODS: Retrospective database review of 67 individuals with moderate-to-severe TBI admitted to a specialised inpatient TBI program. Outcome measures are as follows: (1) functional independence measure + functional assessment measure (FIM+FAM; admission, discharge, change scores); (2) discharge designation (community vs...
May 8, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29732456/a-quality-initiative-for-optimal-therapeutic-hypothermia-during-transport-for-neonates-with-neonatal-encephalopathy
#12
Stephanie L Bourque, Stephanie A Meier, Claire Palmer, Diane L Melara, Theresa R Grover, Cassidy A Delaney
Introduction: Neuroprotection with therapeutic hypothermia (TH) is standard of care for neonatal encephalopathy (NE) and decreases death and neurodevelopmental disability. TH initiated shortly after birth insult results in greater neuroprotection compared with delayed initiation. Methods: Quality improvement methodology was used to improve temperature control during transport to a level IV neonatal intensive care unit. We included neonates with NE transported to a single institution for TH from 2010 to 2016...
March 2018: Pediatric quality & safety
https://www.readbyqxmd.com/read/29721246/acute-encephalopathy-with-biphasic-seizures-and-late-reduced-diffusion-associated-with-streptococcus-sanguinis-sepsis
#13
Hitoshi Awaguni, Jun Shinozuka, Shin-Ichiro Tanaka, Sayaka Kadowaki, Shigeru Makino, Rikken Maruyama, Yosuke Shigematsu, Kenji Hamaoka, Shinsaku Imashuku
Acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) develops in association with systemic as well as central nervous system (CNS) viral or bacterial infections. AESD is most often noted with influenza or human herpesvirus 6 infection in previously healthy infants. However, AESD has also been reported in an infant with developmental retardation and in a mentally and motor-disabled adolescent. Here, we report the case of a 4- year-old female with significant development delay due to spinal muscular atrophy, who developed AESD during Streptococcus sanguinis sepsis with no apparent CNS infection...
March 22, 2018: Pediatric Reports
https://www.readbyqxmd.com/read/29720441/declining-rate-and-severity-of-hospitalized-stroke-from-2004-to-2013-the-national-acute-stroke-israeli-registry
#14
Silvia Koton, Diklah Geva, Jonathan Y Streifler, Sagi Harnof, Yoav Pougach, Olga Azrilin, Shoshana Hadar, Natan M Bornstein, David Tanne
BACKGROUND AND PURPOSE: Stroke is a leading cause of morbidity and disability. We assessed trends in rates of hospitalized stroke and stroke severity on admission in a prospective national registry of stroke from 2004 to 2013. METHODS: All 6693 acute ischemic strokes and intracerebral hemorrhage in the National Acute Stroke Israeli participants ≥20 years old were included. Data were prospectively collected in 2004 (February-March), 2007 (March-April), 2010 (April-May), and 2013 (March-April)...
May 2, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29719039/prognostic-effect-of-changes-in-physical-function-over-prior-year-on-subsequent-mortality-and-long-term-nursing-home-admission
#15
Thomas M Gill, Ling Han, Evelyne A Gahbauer, Linda Leo-Summers, Heather G Allore
OBJECTIVES: To evaluate the prognostic effect of changes in physical function at different intervals over the prior year on subsequent outcomes after accounting for present function. DESIGN: Prospective longitudinal study. SETTING: Greater New Haven, Connecticut, from March 1998 to January 2006. PARTICIPANTS: Community-living persons aged 71 and older who completed an 18-month comprehensive assessment (N=658). MEASUREMENTS: Disability in 13 activities of daily living, instrumental activities of daily living, and mobility activities was assessed at the 18-month comprehensive assessment and at 12, 6, and 3 months before 18 months...
May 2, 2018: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/29719034/measuring-functional-status-in-hospitalized-older-adults-through-electronic-health-record-documentation
#16
Liron Sinvani, Andrzej Kozikowski, Vidhi Patel, Colm Mulvany, Christopher Smilios, Guang Qiu, Meng Zhang, Gisele Wolf-Klein, Renee Pekmezaris
OBJECTIVES: Hospitalization-associated disability affects up to 60% of older adults; however, standardized measures of function are not routinely used and documented. We sought to determine whether nursing documentation in electronic medical records can be used to determine mobility status and associated clinical outcomes. METHODS: A retrospective study of 2383 medical patients aged 75 years and older was conducted at a large academic tertiary hospital in New York...
April 2018: Southern Medical Journal
https://www.readbyqxmd.com/read/29713294/characteristics-and-pathways-of-long-stay-patients-in-high-and-medium-secure-settings-in-england-a-secondary-publication-from-a-large-mixed-methods-study
#17
Birgit A Völlm, Rachel Edworthy, Nick Huband, Emily Talbot, Shazmin Majid, Jessica Holley, Vivek Furtado, Tim Weaver, Ruth McDonald, Conor Duggan
Background: Many patients experience extended stays within forensic care, but the characteristics of long-stay patients are poorly understood. Aims: To describe the characteristics of long-stay patients in high and medium secure settings in England. Method: Detailed file reviews provided clinical, offending and risk data for a large representative sample of 401 forensic patients from 2 of the 3 high secure settings and from 23 of the 57 medium secure settings in England on 1 April 2013. The threshold for long-stay status was defined as 5 years in medium secure care or 10 years in high secure care, or 15 years in a combination of high and medium secure settings...
2018: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/29707176/predictors-of-short-term-mortality-after-acute-stroke-in-east-azerbaijan-province-2014
#18
Seyed Morteza Shamshirgaran, Hamid Barzkar, Darioush Savadi-Oskouei, Mohammad Yazdchi Marandi, Abdolrasoul Safaiyan, Ehsan Sarbazi, Hossein Novbakht, Saber Gaffari
Introduction: Stroke is one of the important causes of death and disability in Iran. This study aimed to examine the factors influencing the short-term mortality of stroke in Northwest of Iran. Methods: Study population were all patients with confirming the diagnosis of the first-ever stroke who were hospitalized in two referral teaching hospitals from October 2013 to March 2015. They were followed up to 30 days after onset of stroke. A neurology year three resident was responsible for extracting the clinical data and assessment of stroke severity on admission using National Institute of Health Stroke Scale (NIHSS), and information about risk factors and socio-demographic factors were collected using face to face interview...
2018: Journal of Cardiovascular and Thoracic Research
https://www.readbyqxmd.com/read/29705803/lipid-lowering-pretreatment-and-outcome-following-intravenous-thrombolysis-for-acute-ischaemic-stroke-a-post-hoc-analysis-of-the-enhanced-control-of-hypertension-and-thrombolysis-stroke-study-trial
#19
Jatinder S Minhas, Xia Wang, Hisatomi Arima, Philip M Bath, Laurent Billot, Joseph P Broderick, Geoffrey A Donnan, Jong S Kim, Pablo M Lavados, Tsong-Hai Lee, Sheila Cristina Ouriques Martins, Verónica V Olavarría, Jeyaraj D Pandian, Octávio Marques Pontes-Neto, Stefano Ricci, Shoichiro Sato, Vijay K Sharma, Nguyen H Thang, Ji-Guang Wang, Mark Woodward, John Chalmers, Craig S Anderson, Thompson G Robinson
BACKGROUND: Debate exists as to whether statin pretreatment confers an increased risk of 90-day mortality and symptomatic intracranial haemorrhage (sICH) in acute ischaemic stroke (AIS) patients treated with intravenous thrombolysis. We assessed the effects of undifferentiated lipid-lowering pretreatment on outcomes and interaction with low-dose versus standard-dose alteplase in a post hoc subgroup -analysis of the Enhanced Control of Hypertension and Thrombolysis Stroke Study. METHODS: In all, 3,284 thrombolysis-eligible AIS patients (mean age 66...
April 27, 2018: Cerebrovascular Diseases
https://www.readbyqxmd.com/read/29705763/development-of-prediction-models-of-stress-and-long-term-disability-among-claimants-to-injury-compensation-systems-a-cohort-study
#20
Matthew J Spittal, Genevieve Grant, Meaghan O'Donnell, Alexander C McFarlane, David M Studdert
OBJECTIVES: We sought to develop prognostic risk scores for compensation-related stress and long-term disability using markers collected within 3 months of a serious injury. DESIGN: Cohort study. Predictors were collected at baseline and at 3 months postinjury. Outcome data were collected at 72 months postinjury. SETTING: Hospitalised patients with serious injuries recruited from four major trauma hospitals in Australia. PARTICIPANTS: 332 participants who made claims for compensation for their injuries to a transport accident scheme or a workers' compensation scheme...
April 28, 2018: BMJ Open
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