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infant motor development

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https://www.readbyqxmd.com/read/28439323/caudal-regression-syndrome-a-case-series-of-a-rare-congenital-anomaly
#1
Yogesh Kumar, Nishant Gupta, Kusum Hooda, Pranav Sharma, Salil Sharma, Puneet Kochar, Daichi Hayashi
BACKGROUND: Caudal regression syndrome is a rare, neural tube defect characterized by an abnormal development of the caudal aspect of the vertebral column and the spinal cord., It results in neurological deficits ranging from bladder and bowel involvement to severe sensory and motor deficits in the lower limbs. Maternal diabetes, genetic factors and some teratogens have been shown to be associated with its pathogenesis. Caudal regression syndrome is usually diagnosed initially by antenatal ultrasound with more definitive diagnosis made by antenatal or postnatal MRI...
2017: Polish Journal of Radiology
https://www.readbyqxmd.com/read/28437326/favorable-outcomes-of-preterm-infants-with-parenteral-nutrition-associated-liver-disease-treated-with-intravenous-fish-oil-based-lipid-emulsion
#2
Michael Sorrell, Alvaro Moreira, Kay Green, Rachel Jacob, Robin Tragus, Laura Keller, Amy Quinn, Donald McCurnin, Alice Gong, Abeer El Sakka, Naveen Mittal, Cynthia Blanco
OBJECTIVES: The aim of the study was to determine the acute and long-term outcomes of preterm infants treated with an intravenous fish oil-based lipid emulsion (FishLE) for parenteral nutrition-associated liver disease (PNALD). METHODS: Preterm infants 14 days to 24 months of age with anatomic short gut or severe intestinal dysmotility, serum direct bilirubin ≥4 mg/dL, and requiring >60% calories from parenteral nutrition were eligible. Enrolled infants received 1 g · kg · day of FishLE until resolution of direct hyperbilirubinemia or return of enteral nutrition...
May 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28433877/affordances-in-the-home-environment-for-motor-development-validity-and-reliability-for-the-use-in-daycare-setting
#3
Alessandra Bombarda Müller, Nadia Cristina Valentini, Paulo Felipe Ribeiro Bandeira
The range of stimuli provided by physical space, toys and care practices contributes to the motor, cognitive and social development of children. However, assessing the quality of child education environments is a challenge, and can be considered a health promotion initiative. This study investigated the validity of the criterion, content, construct and reliability of the Affordances in the Home Environment for Motor Development - Infant Scale (AHEMD-IS), version 3-18 months, for the use in daycare settings...
April 20, 2017: Infant Behavior & Development
https://www.readbyqxmd.com/read/28424357/thin-for-gestational-age-infants-are-at-increased-risk-of-neurodevelopmental-delay-at-2%C3%A2-years
#4
Sinéad M O'Neill, Geraldine Hannon, Ali S Khashan, J O'B Hourihane, Louise C Kenny, Mairead Kiely, Deirdre M Murray
BACKGROUND: Infants born small-for-gestational age (SGA) are at increased risk of developmental difficulties. Identifying those most at risk is challenging. We examined the effect of neonatal body composition and customised birthweight centiles on neurocognitive and behavioural outcomes at age 2. STUDY DESIGN: Prospective cohort study of term infants from the Cork BASELINE Birth Cohort Study classified into the following exposure groups: a birth weight <10th customised centile (SGA, n=51); body fat percentage at birth <10th centile (thin-for-gestational age (TGA, n=51)) or both SGA and TGA infants (small- and thin-for-gestational age (STGA), n=13)...
May 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28420388/association-between-maternal-intake-of-n-6-to-n-3-fatty-acid-ratio-during-pregnancy-and-infant-neurodevelopment-at-6-months-of-age-results-of-the-moceh-cohort-study
#5
Hyejin Kim, Hyesook Kim, Eunjung Lee, Yeni Kim, Eun-Hee Ha, Namsoo Chang
BACKGROUND & AIMS: Long-chain polyunsaturated fatty acids (LC-PUFAs) are essential for infant neurodevelopment. The nutritional adequacy of dietary LC-PUFAs depends not only on the LC-PUFAs intake but also on the n-6 to n-3 fatty acid ratio (n-6/n-3 PUFAs). This study aimed to identify the association between the maternal dietary n-6/n-3 PUFAs and motor and cognitive development of infants at 6 months of age. METHODS: We used data from 960 participants in the Mothers and Children's Environmental Health (MOCEH) study, which is a multi-center prospective cohort study...
April 18, 2017: Nutrition Journal
https://www.readbyqxmd.com/read/28417256/to-which-extent-social-withdrawal-at-the-age-of-1%C3%A2-year-is-associated-with-iq-at-5-6%C3%A2-years-old-results-of-the-eden-mother-child-cohort
#6
Antoine Guedeney, Sarah Doukhan, Anne Forhan, Barbara Heude, Hugo Peyre
The present study aims to determine to which extent social withdrawal at 1 year is associated with the child's IQ at the end of the preschool period. Children (N = 1045) from the EDEN mother-child cohort were assessed for social withdrawal behaviours at 1 year by trained midwives using the Alarm Distress BaBy (ADBB) scale. Midwives also examined infants' language and motor development at 1 year. At the age 5-6 years, IQ scores were based on the WPPSI-III. Linear regression models were used to determine the association between IQ and ADBB, adjusted for a broad range of pre- and postnatal environmental factors and for language and motor skills scores at 1 year...
April 17, 2017: European Child & Adolescent Psychiatry
https://www.readbyqxmd.com/read/28416458/on-the-origins-of-sex-based-differences-in-respiratory-disorders-lessons-and-hypotheses-from-stress-neuroendocrinology-in-developing-rats
#7
REVIEW
Jean-Philippe Rousseau, Luana Tenorio-Lopes, Cécile Baldy, Tara Adele Janes, Stéphanie Fournier, Richard Kinkead
The environment plays a critical role in shaping development and function of the brain. Stress, especially when experienced early in life, can interfere with these processes. In the context of respiratory control, perinatal stress can therefore alter the ability to achieve the "fine-tuning" necessary for proper detection of chemosensory stimuli and production of an adequate motor (respiratory) command. Depending on the timing, intensity, and duration, the detrimental consequences of perinatal exposure to adverse conditions on the respiratory network become manifest at various life stages and can persist into adulthood...
April 14, 2017: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/28412592/infants-motor-simulation-of-observed-actions-is-modulated-by-the-visibility-of-the-actor-s-body
#8
Ty W Boyer, Samuel M Harding, Bennett I Bertenthal
Previous research suggests that 9-month-old infants will develop a response bias in the A-not-B search paradigm after only observing an experimenter search for a hidden object on A-trials. In the current experiment, we tested whether infants would persist in making errors when only the hands-and-arms of the experimenter were visible. Three different conditions were included: (1) the experimenter was silent while hiding and finding the object, (2) the experimenter communicated with the infant via infant-directed speech, or (3) the body of the experimenter was visible during the training phase before his head and body were occluded during the test phase...
April 13, 2017: Cognition
https://www.readbyqxmd.com/read/28411446/a-study-of-reaching-actions-in-walking-infants
#9
Jill A Dosso, Sandra V Herrera, J Paul Boudreau
Acquiring motor skills transforms the perceptual and cognitive world of infants and expands their exploratory engagement with objects. This study investigated how reaching is integrated with walking among infant walkers (n=23, 14.5-15.5 months). In a walk-to-reach paradigm, diverse object retrieval strategies were observed. All infants were willing to use their upper and lower bodies in concert, and the timing of this coordination reflected features of their environment. Infants with an older walking age (months since walking onset) retrieved items more rapidly and exploited their non-reaching hand more effectively during object retrieval than did same-age infants with a younger walking age...
April 12, 2017: Infant Behavior & Development
https://www.readbyqxmd.com/read/28400976/iss-n1-makes-the-first-fda-approved-drug-for-spinal-muscular-atrophy
#10
Eric W Ottesen
Spinal muscular atrophy (SMA) is one of the leading genetic diseases of children and infants. SMA is caused by deletions or mutations of Survival Motor Neuron 1 (SMN1) gene. SMN2, a nearly identical copy of SMN1, cannot compensate for the loss of SMN1 due to predominant skipping of exon 7. While various regulatory elements that modulate SMN2 exon 7 splicing have been proposed, intronic splicing silencer N1 (ISS-N1) has emerged as the most promising target thus far for antisense oligonucleotide-mediated splicing correction in SMA...
January 2017: Translational Neuroscience
https://www.readbyqxmd.com/read/28393740/precursors-to-language-development-in-typically-and-atypically-developing-infants-and-toddlers-the-importance-of-embracing-complexity
#11
Dean D'Souza, Hana D'Souza, Annette Karmiloff-Smith
In order to understand how language abilities emerge in typically and atypically developing infants and toddlers, it is important to embrace complexity in development. In this paper, we describe evidence that early language development is an experience-dependent process, shaped by diverse, interconnected, interdependent developmental mechanisms, processes, and abilities (e.g. statistical learning, sampling, functional specialization, visual attention, social interaction, motor ability). We also present evidence from our studies on neurodevelopmental disorders (e...
April 10, 2017: Journal of Child Language
https://www.readbyqxmd.com/read/28389270/combination-of-valproic-acid-and-morpholino-splice-switching-oligonucleotide-produces-improved-outcomes-in-spinal-muscular-atrophy-patient-derived-fibroblasts
#12
Anna Farrelly-Rosch, Chew Ling Lau, Nitin Patil, Bradley J Turner, Fazel Shabanpoor
Spinal muscular atrophy (SMA), the leading genetic cause of infant mortality worldwide, is characterised by the homozygous loss of the survival motor neuron 1 (SMN1) gene. The consequent degeneration of spinal motor neurons and progressive atrophy of voluntary muscle groups results in paralysis and eventually premature infantile death. Humans possess a second nearly identical copy of SMN1, known as SMN2. However, SMN2 produces only 10-20% functional SMN protein due to aberrant splicing of its pre-mRNA that leads to the exclusion of exon 7...
April 4, 2017: Neurochemistry International
https://www.readbyqxmd.com/read/28386948/developmental-pathways-in-infants-from-4-to-24%C3%A2-months
#13
L Valla, M S Birkeland, D Hofoss, K Slinning
BACKGROUND: There has been limited epidemiological research describing population-based samples regarding developmental pathways throughout infancy, and the research that exists has revealed substantial diversity. Identifying predictors for developmental pathways can inform early intervention services. METHODS: The Ages and Stages Questionnaire was used to measure communication, gross motor, fine motor, problem-solving and personal-social skills longitudinally in a large, population-based sample of 1555 infants recruited from well-baby clinics in five municipalities in southeast Norway...
April 7, 2017: Child: Care, Health and Development
https://www.readbyqxmd.com/read/28385091/early-postoperative-physical-therapy-for-improving-short-term-gross-motor-outcome-in-infants-with-cyanotic-and-acyanotic-congenital-heart-disease
#14
Sumihito Haseba, Harutoshi Sakakima, Syuhei Nakao, Misaki Ohira, Shigefumi Yanagi, Yutaka Imoto, Akira Yoshida, Megumi Shimodozono
PURPOSE: We analysed the gross motor recovery of infants and toddlers with cyanotic and acyanotic congenital heart disease (CHD) who received early postoperative physical therapy to see whether there was any difference in the duration to recovery. METHODS: This study retrospectively evaluated the influence of early physical therapy on postoperative gross motor outcomes of patients with CHD. The gross motor ability of patients with cyanotic (n = 25, average age: 376...
April 7, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28376931/developmental-screening-in-children-with-chd-ages-and-stages-questionnaires
#15
Maia M Noeder, Beth A Logan, Kari L Struemph, Nancy Condon, Isabel Mueller, Barbara Sands, Ryan R Davies, Erica Sood
OBJECTIVE: Standardised developmental screening tools are important for the evaluation and management of developmental disorders in children with CHD; however, psychometric properties and clinical utility of screening tools, such as the Ages & Stages Questionnaires, Third Edition (ASQ-3), have not been examined in the CHD population. We hypothesised that the ASQ-3 would be clinically useful for this population. Study design ASQ-3 developmental classifications for 163 children with CHD at 6, 12, 24, and/or 36 months of age were compared with those obtained from concurrent developmental testing with the Bayley Scales of Infant and Toddler Development, Third Edition...
April 5, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28370151/outcome-of-isolated-enlarged-cisterna-magna-identified-in-utero-experience-at-a-single-medical-center-in-mainland-china
#16
Liu Zequn, Jin Han, Fu Fang, Juan Liu, Li Ru, Yang Xin, Pan Min, Zhen Li, Li Dongzhi, Liao Can
OBJECTIVE: To explore the effects of prenatal isolated enlarged cisterna magna (IECM) on postnatal development. METHODS: We followed up 123 fetuses with an enlarged cisterna magna (ECM), who were divided into IECM (Group 1) and non-IECM (ECM plus other anomalies, Group 2) groups, and compared with 60 normal infants with normal fetal ultrasound. We assessed infants postnatally using the Gesell Developmental Schedules. Fetal magnetic resonance imaging, karyotyping and chromosomal microarray analysis test were offered...
March 30, 2017: Prenatal Diagnosis
https://www.readbyqxmd.com/read/28362900/the-davida-teller-award-lecture-2016-visual-brain-development-a-review-of-dorsal-stream-vulnerability-motion-mathematics-amblyopia-actions-and-attention
#17
Janette Atkinson
Research in the Visual Development Unit on "dorsal stream vulnerability' (DSV) arose from research in two somewhat different areas. In the first, using cortical milestones for local and global processing from our neurobiological model, we identified cerebral visual impairment in infants in the first year of life. In the second, using photo/videorefraction in population refractive screening programs, we showed that infant spectacle wear could reduce the incidence of strabismus and amblyopia, but many preschool children, who had been significantly hyperopic earlier, showed visuo-motor and attentional deficits...
March 1, 2017: Journal of Vision
https://www.readbyqxmd.com/read/28361282/prenatal-maternal-distress-seems-to-be-associated-with-the-infant-s-temperament-and-motor-development-an-explorative-study
#18
Christin Haselbeck, Uwe Niederberger, Alexandra Kulle, Katharina Wache, Ellen Brauner, Merlin Gutermuth, Paul-Martin Holterhus, Wolf-Dieter Gerber, Michael Siniatchkin
According to the concept of fetal programming, prenatal distress has long-lasting consequences on the offspring's health later in life. The hypothalamic-pituitary-adrenal axis is considered a mediating system by which maternal distress is transferred to the fetus in intrauterine environment. In this longitudinal explorative study on 30 mother-child-dyads, reported maternal distress and salivary cortisol were collected during pregnancy. Infant temperament, motor and cognitive development were assessed at 16 months...
March 30, 2017: Journal of Neural Transmission
https://www.readbyqxmd.com/read/28350777/understanding-brain-reorganization-in-infants-with-perinatal-stroke-through-neuroexcitability-and-neuroimaging
#19
Chao-Ying Chen, Michael Georgieff, Jed Elison, Mo Chen, James Stinear, Bryon Mueller, Raghavendra Rao, Kyle Rudser, Bernadette Gillick
PURPOSE: The primary aim of this proposed study is to evaluate brain reorganization patterns in infants with perinatal stroke between 3 and 5 months of age using transcranial magnetic stimulation and magnetic resonance imaging, with the addition of the General Movements Assessment. A secondary aim is to demonstrate feasibility and safety of infant-appropriate brain assessment protocols. METHODS: Ten infants with perinatal stroke will be enrolled. In this exploratory study, infants will first receive magnetic resonance imaging scanning during natural sleep to examine their corticospinal tract integrity...
April 2017: Pediatric Physical Therapy
https://www.readbyqxmd.com/read/28350771/concurrent-validity-between-live-and-home-video-observations-using-the-alberta-infant-motor-scale
#20
Marike Boonzaaijer, Ellen van Dam, Ingrid C van Haastert, Jacqueline Nuysink
PURPOSE: Serial assessment of gross motor development of infants at risk is an established procedure in neonatal follow-up clinics. Assessments based on home video recordings could be a relevant addition. METHODS: In 48 infants (1.5-19 months), the concurrent validity of 2 applications was examined using the Alberta Infant Motor Scale: (1) a home video made by parents and (2) simultaneous observation on-site by a pediatric physical therapist. Parents' experiences were explored using a questionnaire...
April 2017: Pediatric Physical Therapy
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