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infant motor development

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https://www.readbyqxmd.com/read/28100326/-feeding-difficulty-and-developmental-delay-for-8-months-and-nystagmus-for-4-months-in-an-infant
#1
Jie Zhu, Fei Yu
Aromatic L-amino acid decarboxylase (AADC) deficiency is a rare autosomal recessive hereditary disease and is a congenital metabolic disorder of neurotransmitter biosynthesis. It is mainly manifested as hypotonia, oculogyric crisis, autonomic dysfunction, and developmental delay. This article reports a boy manifested as delayed motor development, hypotonia, and oculogyric crisis. Gene screening for metabolic disorders revealed new compound heterozygous mutations, c.1063dupA (p.I355fs) and c.250A>C (p.S84R), in the exon of DDC gene...
January 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28088692/evaluation-of-motor-and-cognitive-development-among-infants-exposed-to-hiv
#2
Kaitiana Martins da Silva, Cristina Dos Santos Cardoso de Sá, Raquel Carvalho
This study of a prospective and cross-sectional nature compared the motor and cognitive development of HIV-exposed and unexposed infants in their first 18months of age. 40 infants exposed to HIV and antiretroviral therapy (Experimental Group - EG) and 40 unexposed infants (Control Group - CG) participated in the study. They were divided into four age groups of 4, 8, 12 and 18months old, with 10 infants from EG and 10 from CG in each group. The infants were evaluated once on motor and cognitive development by the Bayley Scale of Infant and Toddler Development...
January 12, 2017: Early Human Development
https://www.readbyqxmd.com/read/28087725/neurodevelopmental-outcomes-of-extremely-low-birthweight-infants-randomised-to-different-pco2-targets-the-phelbi-follow-up-study
#3
Ulrich H Thome, Orsolya Genzel-Boroviczeny, Bettina Bohnhorst, Manuel Schmid, Hans Fuchs, Oliver Rohde, Stefan Avenarius, Hans-Georg Topf, Andrea Zimmermann, Dirk Faas, Katharina Timme, Barbara Kleinlein, Horst Buxmann, Wilfried Schenk, Hugo Segerer, Norbert Teig, Annett Bläser, Roland Hentschel, Matthias Heckmann, Rolf Schlösser, Jochen Peters, Rainer Rossi, Wolfgang Rascher, Ralf Böttger, Jürgen Seidenberg, Gesine Hansen, Maria Zernickel, Harald Bode, Jens Dreyhaupt, Rainer Muche, Helmut D Hummler
BACKGROUND: Tolerating higher partial pressures of carbon dioxide (PCO2) in mechanically ventilated extremely low birthweight infants to reduce ventilator-induced lung injury may have long-term neurodevelopmental side effects. This study analyses the results of neurodevelopmental follow-up of infants enrolled in a randomised multicentre trial. METHODS: Infants (n=359) between 400 and 1000 g birth weight and 23 0/7-28 6/7 weeks gestational age who required endotracheal intubation and mechanical ventilation within 24 hours of birth were randomly assigned to high PCO2 or to a control group with mildly elevated PCO2 targets...
January 13, 2017: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/28079770/neurodevelopmental-outcomes-after-assisted-reproductive-technologies
#4
Jacques Balayla, Odile Sheehy, William D Fraser, Jean R Séguin, Jacquetta Trasler, Patricia Monnier, Andrea A MacLeod, Marie-Noëlle Simard, Gina Muckle, Anick Bérard
OBJECTIVE: To compare children's cognitive, motor, and language development at 2 years of age after assisted reproductive technologies (ARTs) relative to natural conception. METHODS: The 3D-Study (2010-2012) is a prospective cohort study, which sought to improve the understanding among perinatal events, obstetric outcomes, and child development. A total of 2,366 pregnant women were recruited, of whom 278 conceived with ART: ovarian stimulation, intrauterine sperm insemination, in vitro fertilization, intracytoplasmic sperm injection, or in vitro maturation...
January 9, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28068465/one-year-developmental-outcomes-for-infants-of-mothers-with-bipolar-disorder
#5
Aimee K Santucci, Lynn T Singer, Stephen R Wisniewski, James F Luther, Heather F Eng, Dorothy K Sit, Katherine L Wisner
OBJECTIVE: Few data about the development of infants born to women with bipolar disorder have been published. We hypothesized that infants of women with bipolar disorder (by DSM-IV criteria) treated with psychotropics (BD+) or untreated with psychotropics (BD-) would demonstrate poorer cognitive and behavioral development than infants of controls. On the basis of previous studies, we expected that psychotropic-exposed infants of women in the BD+ group would have poorer neuromotor performance during infancy...
January 3, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28049268/local-food-supplementation-and-psychosocial-stimulation-improve-linear-growth-and-cognitive-development-among-indonesian-infants-aged-6-to-9-months
#6
Helmizar Helmizar, Fasli Jalal, Nur Indrawati Lipoeto, Endang L Achadi
BACKGROUND AND OBJECTIVES: To evaluate the effect of culturally-relevant food supplementation and psychosocial stimulation on infant growth and development. METHODS AND STUDY DESIGN: A community-based randomized controlled trial was conducted in 40 clusters from 5 selected villages in Tanah Datar District of West Sumatera, Indonesia. We assessed 355 infants aged 6 to 9 months at the beginning of the study. The infants were divided into 4 groups: 1) Food Supplementation (FS); 2) Psychosocial Stimulation (PS); 3) Food Supplementation and Psychosocial Stimulation (FS+PS); and 4) Control Group (CG)...
January 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28031374/large-scale-behavior-change-initiative-for-infant-and-young-child-feeding-advanced-language-and-motor-development-in-a-cluster-randomized-program-evaluation-in-bangladesh
#7
Edward A Frongillo, Phuong H Nguyen, Kuntal K Saha, Tina Sanghvi, Kaosar Afsana, Raisul Haque, Jean Baker, Marie T Ruel, Rahul Rawat, Purnima Menon
BACKGROUND: Promoting adequate nutrition through interventions to improve infant and young child feeding (IYCF) has the potential to contribute to child development. OBJECTIVE: We examined whether an intensive intervention package that was aimed at improving IYCF at scale through the Alive & Thrive initiative in Bangladesh also advanced language and gross motor development, and whether advancements in language and gross motor development were explained through improved complementary feeding...
December 28, 2016: Journal of Nutrition
https://www.readbyqxmd.com/read/28024255/dual-route-imitation-in-preschool-children
#8
Linda Sebastianutto, Paola Mengotti, Caterina Spiezio, Raffaella Ida Rumiati, Evan Balaban
Imitation can be realized via two different routes: a direct route that translates visual input into motor output when gestures are meaningless or unknown, and a semantic route for known/meaningful gestures. Young infants show imitative behaviours compatible with the direct route, but little is known about the development of the semantic route, studied here for the first time. The present study examined preschool children (3-5years of age) imitating gestures that could be transitive or intransitive, and meaningful or meaningless...
December 23, 2016: Acta Psychologica
https://www.readbyqxmd.com/read/28017471/the-antisense-transcript-smn-as1-regulates-smn-expression-and-is-a-novel-therapeutic-target-for-spinal-muscular-atrophy
#9
Constantin d'Ydewalle, Daniel M Ramos, Noah J Pyles, Shi-Yan Ng, Mariusz Gorz, Celeste M Pilato, Karen Ling, Lingling Kong, Amanda J Ward, Lee L Rubin, Frank Rigo, C Frank Bennett, Charlotte J Sumner
The neuromuscular disorder spinal muscular atrophy (SMA), the most common inherited killer of infants, is caused by insufficient expression of survival motor neuron (SMN) protein. SMA therapeutics development efforts have focused on identifying strategies to increase SMN expression. We identified a long non-coding RNA (lncRNA) that arises from the antisense strand of SMN, SMN-AS1, which is enriched in neurons and transcriptionally represses SMN expression by recruiting the epigenetic Polycomb repressive complex-2...
January 4, 2017: Neuron
https://www.readbyqxmd.com/read/28009726/the-emergence-of-autism-spectrum-disorder-insights-gained-from-studies-of-brain-and-behaviour-in-high-risk-infants
#10
Kandice J Varcin, Shafali S Jeste
PURPOSE OF REVIEW: We review studies of infants at risk for autism spectrum disorder (ASD), proposing that the earliest manifestations of disrupted brain development can shed light on prebehavioural markers of risk and mechanisms underlying the heterogeneity of ASD. RECENT FINDINGS: Prospective, longitudinal studies of infants at risk for ASD have revealed that behavioural signs of ASD are generally not observed until the second year of life. The developmental signs within the first year are often subtle and rooted in processes outside the core diagnostic domains of ASD, such as motor and visual perceptual function...
December 21, 2016: Current Opinion in Psychiatry
https://www.readbyqxmd.com/read/28005729/assessment-of-deformational-plagiocephaly-severity-and-neonatal-developmental-delay
#11
Stefani C Fontana, Debora Daniels, Thomas Greaves, Niaman Nazir, Jeff Searl, Brian T Andrews
Deformational plagiocephaly (DP) in infants has been associated with developmental delay that can last until adolescence. Despite this association and a 5-fold increase in incidence of DP over the past 2 decades, there are currently no guidelines regarding screening for developmental delay or identification of which infants with DP are at the greatest risk of delay. A prospective, nonrandomized study was performed. Infants diagnosed with DP who had no prior intervention were eligible for enrollment. Cranial deformity was measured by cross-cranial measurements using calipers, and developmental delay was measured using the Bayley Scales of Infant and Toddler Development, Third Edition (Bayley-III)...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28004392/a-critical-period-of-corticomuscular-and-emg-emg-coherence-detection-in-9-25-week-old-healthy-infants
#12
Anina Ritterband-Rosenbaum, Anna Herskind, Xi Li, Maria Willerslev-Olsen, Mikkel Damgaard Olsen, Simon Francis Farmer, Jens Bo Nielsen
The early postnatal development of functional corticospinal connections in human infants is not fully clarified. We used EEG and EMG to investigate the development of corticomuscular and intramuscular coherence as indicators of functional corticospinal connectivity in healthy infants aged 1-66 weeks. EEG was recorded over leg and hand area of motor cortex. EMG recordings were made from right ankle dorsiflexor and right wrist extensor muscles. Quantification of the amount of corticomuscular coherence in the 20-40 Hz frequency band showed a significantly larger coherence for infants aged 9-25 weeks compared to younger and older infants...
December 22, 2016: Journal of Physiology
https://www.readbyqxmd.com/read/27984474/importance-of-initiating-a-tummy-time-intervention-early-in-infants-with-down-syndrome
#13
Erin E Wentz
PURPOSE: This study compared differences in motor development in infants with Down syndrome beginning a tummy time intervention before 11 weeks of age and after 11 weeks of age. METHODS: Nineteen infants with Down syndrome participated in tummy time until they could independently transition in and out of sitting. Motor development was assessed monthly using the Bayley III Motor Scales and compared between the groups. RESULTS: A difference in motor development between early and late groups is apparent 1, 2, and 3 months following intervention initiation...
January 2017: Pediatric Physical Therapy
https://www.readbyqxmd.com/read/27983664/a-review-of-wearable-sensor-systems-for-monitoring-body-movements-of-neonates
#14
REVIEW
Hongyu Chen, Mengru Xue, Zhenning Mei, Sidarto Bambang Oetomo, Wei Chen
Characteristics of physical movements are indicative of infants' neuro-motor development and brain dysfunction. For instance, infant seizure, a clinical signal of brain dysfunction, could be identified and predicted by monitoring its physical movements. With the advance of wearable sensor technology, including the miniaturization of sensors, and the increasing broad application of micro- and nanotechnology, and smart fabrics in wearable sensor systems, it is now possible to collect, store, and process multimodal signal data of infant movements in a more efficient, more comfortable, and non-intrusive way...
December 14, 2016: Sensors
https://www.readbyqxmd.com/read/27976377/association-between-corpus-callosum-development-on-magnetic-resonance-imaging-and-diffusion-tensor-imaging-and-neurodevelopmental-outcome-in-neonates-born-very-preterm
#15
Anna M Malavolti, Vann Chau, Meisan Brown-Lum, Kenneth J Poskitt, Rollin Brant, Anne Synnes, Ruth E Grunau, Steven P Miller
AIM: To characterize corpus callosum development in neonates born very preterm from early in life to term-equivalent age and its relationship with neurodevelopmental outcome at 18 months corrected age. METHOD: In a prospective cohort of 193 neonates born preterm, 24 to 32 weeks' gestation, we used magnetic resonance imaging and diffusion tensor imaging acquired early in life (n=193) and at term-equivalent age (n=159) to measure corpus callosum development: mid-sagittal area (including corpus callosum subdivisions) and length, and fractional anisotropy from the genu and splenium...
December 14, 2016: Developmental Medicine and Child Neurology
https://www.readbyqxmd.com/read/27955652/early-skin-to-skin-contact-or-incubator-for-very-preterm-infants-study-protocol-for-a-randomized-controlled-trial
#16
Laila Kristoffersen, Ragnhild Støen, Hilde Rygh, Margunn Sognnæs, Turid Follestad, Hilde S Mohn, Ingrid Nissen, Håkon Bergseng
BACKGROUND: Skin-to-skin care immediately following delivery is a common practice for term infants and has been shown to improve cardiorespiratory stability, facilitate early bonding, and promote breastfeeding. Since 2007, the use of skin-to-skin care has been practiced for preterm infants from 32 weeks of gestation in the delivery room at St. Olav's University Hospital. In the present study we aim to investigate whether skin-to-skin care following delivery is safe, and how it affects early and late outcomes compared to standard care for very preterm infants...
December 12, 2016: Trials
https://www.readbyqxmd.com/read/27940687/survival-and-neurodevelopmental-outcomes-of-preterms-resuscitated-with-different-oxygen-fractions
#17
Nuria Boronat, Marta Aguar, Denise Rook, Martin Iriondo, María Brugada, María Cernada, Antonio Nuñez, Montserrat Izquierdo, Elena Cubells, María Martinez, Anna Parra, Hans van Goudoever, Máximo Vento
BACKGROUND AND OBJECTIVES: Stabilization of preterm infants after birth frequently requires oxygen supplementation. At present the optimal initial oxygen inspiratory fraction (Fio2) for preterm stabilization after birth is still under debate. We aimed to compare neurodevelopmental outcomes of extremely preterm infants at 24 months corrected age randomly assigned to be stabilized after birth with an initial Fio2 of 0.3 versus 0.6 to 0.65 in 3 academic centers from Spain and the Netherlands...
December 2016: Pediatrics
https://www.readbyqxmd.com/read/27940686/school-age-outcomes-of-early-intervention-for-preterm-infants-and-their-parents-a-randomized-trial
#18
Alicia J Spittle, Sarah Barton, Karli Treyvaud, Carly S Molloy, Lex W Doyle, Peter J Anderson
OBJECTIVE: To examine the child and parental outcomes at school age of a randomized controlled trial of a home-based early preventative care program for infants born very preterm and their caregivers. METHODS: At term-equivalent age, 120 infants born at a gestational age of <30 weeks were randomly allocated to intervention (n = 61) or standard care (n = 59) groups. The intervention included 9 home visits over the first year of life focusing on infant development, parental mental health, and the parent-infant relationship...
December 2016: Pediatrics
https://www.readbyqxmd.com/read/27940685/prenatal-iron-deficiency-neonatal-ferritin-and-infant-cognitive-function
#19
Michael O Mireku, Leslie L Davidson, Michael J Boivin, Romeo Zoumenou, Achille Massougbodji, Michel Cot, Florence Bodeau-Livinec
OBJECTIVE: To investigate the impact of prenatal maternal iron deficiency (ID) on cord blood serum ferritin (CBSF) concentration and infant cognitive and motor development. METHODS: Our prospective cohort study included 636 mother-singleton child pairs from 828 eligible pregnant women who were enrolled during their first antenatal care (ANC) visit in Allada, Benin, into a clinical trial comparing the efficacy of mefloquine and sulfadoxine-pyrimethamine. Venous blood samples of women were assessed for ferritin and hemoglobin concentrations at the first and second ANC visits (occurring at least 1-month apart) and at delivery...
December 2016: Pediatrics
https://www.readbyqxmd.com/read/27939123/feeding-methods-at-discharge-predict-long-term-feeding-and-neurodevelopmental-outcomes-in-preterm-infants-referred-for-gastrostomy-evaluation
#20
Sudarshan R Jadcherla, Tanvi Khot, Rebecca Moore, Manish Malkar, Ish K Gulati, Jonathan L Slaughter
OBJECTIVE: To test the hypothesis that oral feeding at first neonatal intensive care unit discharge is associated with less neurodevelopmental impairment and better feeding milestones compared with discharge with a gastrostomy tube (G-tube). STUDY DESIGN: We studied outcomes for a retrospective cohort of 194 neonates <37 weeks' gestation referred for evaluation and management of feeding difficulties between July 2006 and July 2012. Discharge milestones, length of hospitalization, and Bayley Scales of Infant Development-Third Edition scores at 18-24 months were examined...
December 1, 2016: Journal of Pediatrics
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