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https://www.readbyqxmd.com/read/29773577/determinants-and-outcomes-of-vasoplegia-following-left-ventricular-assist-device-implantation
#1
Kristen M Tecson, Brian Lima, Andy Y Lee, Fayez S Raza, Grace Ching, Cheng-Han Lee, Joost Felius, Ronald D Baxter, Sasha Still, Justin D G Collier, Shelley A Hall, Susan M Joseph
BACKGROUND: Vasoplegia is associated with adverse outcomes following cardiac surgery; however, its impact following left ventricular assist device implantation is largely unexplored. METHODS AND RESULTS: In 252 consecutive patients receiving a left ventricular assist device, vasoplegia was defined as the occurrence of normal cardiac function and index but with the need for intravenous vasopressors within 48 hours following surgery for >24 hours to maintain a mean arterial pressure >70 mm Hg...
May 17, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29773566/multisociety-consensus-quality-improvement-revised-consensus-statement-for-endovascular-therapy-of-acute-ischemic-stroke-from-the-american-association-of-neurological-surgeons-aans-american-society-of-neuroradiology-asnr-cardiovascular-and-interventional-radiology
#2
https://www.readbyqxmd.com/read/29772696/the-effect-of-negative-pressure-wound-therapy-with-and-without-instillation-on-mature-biofilms-in-vitro
#3
Shamaila Tahir, Matthew Malone, Honghua Hu, Anand Deva, Karen Vickery
BACKGROUND: To investigate the effect of negative pressure wound therapy (NPWT) with and without instillation (NPWTi) on in vitro mature biofilm. METHODS: Mature biofilms of Pseudomonas aeruginosa and Staphylococcus aureus were grown under shear (130 rpm) on polycarbonate coupons in a CDC biofilm reactor for 3 days. Coupons containing biofilms were placed in a sterile petri dish and sealed using NPWT or NPWTi. Coupons were exposed to treatment for 24 h with NPWT alone or with instillation of: Povidone iodine solution (PVP-I) (10% w / v equivalent to 1% w / v available iodine, BETADINE® , Mundipharma, Singapore), surfactant based antimicrobial solution with polyhexamethylene biguanide (SBPHMB) (Prontosan® , B Braun Medical, Melsungen, Germany), Gentamicin 1 µg/mL (GM) (G1264 Sigma-Aldrich Pty Ltd...
May 16, 2018: Materials
https://www.readbyqxmd.com/read/29771609/achilles-tendon-structure-differs-between-competitive-distance-runners-and-non-runners-despite-no-clinical-signs-or-symptoms-of-mid-substance-tendinopathy
#4
Todd J Hullfish, Kenton L Hagan, Ellen Casey, Josh R Baxter
Achilles tendinopathy affects many running athletes and often leads to chronic pain and functional deficits. While changes in tendon structure have been linked with tendinopathy, the effects of distance running on tendon structure is not well understood. Therefore, the purpose of this study was to characterize structural differences in the Achilles tendons in healthy young adults and competitive distance runners using quantitative ultrasound analyses. We hypothesized that competitive distance runners with no clinical signs or symptoms of tendinopathy would have quantitative signs of tendon damage, characterized by decreased collagen alignment and echogenicity, in addition to previous reports of thicker tendons...
May 17, 2018: Journal of Applied Physiology
https://www.readbyqxmd.com/read/29769826/effects-of-gymnastics-activities-on-bone-accrual-during-growth-a-systematic-review
#5
REVIEW
Jaak Jürimäe, Rita Gruodyte-Raciene, Adam D G Baxter-Jones
The amount of bone gained during childhood and adolescence impacts greatly on lifetime skeletal health. The purpose of this review is to summarize current evidence of the effects of gymnastics activities on bone mineral accrual during growth and to describe possible factors that influence bone mineral gains. The PubMed and SportDiscus databases were searched, and a total of 24 articles met the selection criteria and were included in this review. Artistic and rhythmic gymnasts presented higher bone mineral density and content values compared to untrained controls, despite possible negative effects associated with hormonal levels, dietary restrictions and body fat...
June 2018: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/29766565/a-retrospective-observational-study-of-people-with-type-1-diabetes-with-self-reported-severe-hypoglycaemia-reveals-high-level-of-ambulance-attendance-but-low-levels-of-therapy-change-and-specialist-intervention
#6
B C T Field, R Nayar, A Kilvert, M Baxter, J Hickey, M Cummings, S C Bain
AIM: To evaluate the impact of severe hypoglycaemia on NHS resources and overall glycaemic control in adults with Type 1 diabetes. METHODS: An observational, retrospective study of adults (aged ≥ 18 years) with Type 1 diabetes reporting one or more episodes of severe hypoglycaemia during the preceding 24 months in 10 NHS hospital diabetes centres in England and Wales. The primary outcome was healthcare resource utilization associated with severe hypoglycaemia...
May 15, 2018: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/29761555/computational-optimization-of-graft-tension-in-simulated-superior-capsule-reconstructions
#7
Michael W Hast, Elaine Schmidt, John D Kelly, Josh R Baxter
Superior capsular reconstruction has received increased attention as a surgical technique to address massive 'irreparable' rotator cuff tears; however, the functional limitations and surgical techniques associated with this repair have yet to be sufficiently explored. The goal of this study was to utilize a multidisciplinary approach to characterize the biomechanics of this repair by: 1) identifying activities of daily living that may overburden graft, and 2) optimizing surgical techniques used during implantation...
May 14, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29756846/enabling-highly-effective-boiling-from-superhydrophobic-surfaces
#8
Taylor P Allred, Justin A Weibel, Suresh V Garimella
A variety of industrial applications such as power generation, water distillation, and high-density cooling rely on heat transfer processes involving boiling. Enhancements to the boiling process can improve the energy efficiency and performance across multiple industries. Highly wetting textured surfaces have shown promise in boiling applications since capillary wicking increases the maximum heat flux that can be dissipated. Conversely, highly nonwetting textured (superhydrophobic) surfaces have been largely dismissed for these applications as they have been shown to promote formation of an insulating vapor film that greatly diminishes heat transfer efficiency...
April 27, 2018: Physical Review Letters
https://www.readbyqxmd.com/read/29753801/a-comparative-study-between-2-different-grafts-used-as-patches-after-plaque-incision-and-inflatable-penile-prosthesis-implantation-for-end-stage-peyronie-s-disease
#9
Marco Falcone, Mirko Preto, Carlo Ceruti, Massimiliano Timpano, Giulio Garaffa, Omidreza Sedigh, Mattia Sibona, Marco Oderda, Paolo Gontero, Luigi Rolle
BACKGROUND: Although many grafts have been used for plaque incision with grafting (PIG) and penile prosthesis (PP) implantation, there is no evidence that favors 1 specific graft over another. AIM: To compare fibrin-coated collagen fleece (TachoSil; Baxter International, Deerfield, IL, USA) with porcine small intestinal submucosa (SIS; Cook Biotech, West Lafayette, IN, USA) as grafts. METHODS: From January 2007 to January 2015, 60 non-randomized consecutive patients affected by end-stage Peyronie disease underwent PIG and PP implantation (AMS 700CX; Boston Scientific, Marlborough, MA, USA)...
May 9, 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29747651/the-effects-of-integrated-care-a-systematic-review-of-uk-and-international-evidence
#10
Susan Baxter, Maxine Johnson, Duncan Chambers, Anthea Sutton, Elizabeth Goyder, Andrew Booth
BACKGROUND: Healthcare systems around the world have been responding to the demand for better integrated models of service delivery. However, there is a need for further clarity regarding the effects of these new models of integration, and exploration regarding whether models introduced in other care systems may achieve similar outcomes in a UK national health service context. METHODS: The study aimed to carry out a systematic review of the effects of integration or co-ordination between healthcare services, or between health and social care on service delivery outcomes including effectiveness, efficiency and quality of care...
May 10, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29745310/use-of-living-strategies-among-adults-aging-with-hiv-in-canada-comparison-by-age-group-using-data-from-the-hiv-health-and-rehabilitation-survey
#11
Kelly Kathleen O'Brien, Matthieu Dagenais, Patricia Solomon, Catherine Worthington, Soo Chan Carusone, Francisco Ibáñez-Carrasco, Steven Hanna, Jacqueline Gahagan, Larry Baxter, Gregory Robinson, Patriic Gayle, Dawn James, Tammy Yates
OBJECTIVE: To examine the type and frequency of living strategies used by adults living with HIV. METHODS: We conducted a cross-sectional web-based survey that included 51 living strategies: maintaining sense of control, attitudes and beliefs, blocking HIV out of the mind, and social interaction. We examined the frequency of use and compared the proportion of respondents who engaged in strategies across 3 age-groups (<40 years, 40-49 years, and ≥50 years). RESULTS: Of the 935 participants, the majority were men (79%) and most (≥60%) engaged "most" or "all of the time" in healthy lifestyle strategies and maintained a positive outlook living with HIV...
January 2018: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/29742236/attendance-of-children-and-adolescents-with-psychoactive-substance-use-disorders-performed-by-psychosocial-care-centers-in-brazil-2008-2012
#12
Déborah Santos Conceição, Sérgio Baxter Andreoli, Monique Azevedo Esperidião, Darci Neves Dos Santos
OBJECTIVE: to describe the profile of care for children and adolescents withpsychoactive substance use disorders performed by the Brazilian Psychosocial Care Centers (Centros de Atenção Psicossocial - CAPS) from 2008 to 2012. METHODS: a descriptive study with data from the SUS Outpatient Information System (Sistema de Informações Ambulatoriais do Sistema Único de Saúde - SIA/SUS) and the system of National Registration of Health Establishments (Cadastro Nacional de Estabelecimentos de Saúde - CNES)...
2018: Epidemiologia e Servicos de Saude: Revista do Sistema Unico de Saude do Brasil
https://www.readbyqxmd.com/read/29739914/computed-tomographic-perfusion-predicts-poor-outcomes-in-a-randomized-trial-of-endovascular-therapy
#13
Robert Wannamaker, Taurian Guinand, Bijoy K Menon, Andrew Demchuk, Mayank Goyal, Donald Frei, Aditya Bharatha, Tudor G Jovin, Jai Shankar, Timo Krings, Blaise Baxter, Christine Holmstedt, Richard Swartz, Dar Dowlatshahi, Richard Chan, Donatella Tampieri, Hana Choe, Paul Burns, Nina Gentile, Jeremy Rempel, Ashfaq Shuaib, Brian Buck, Andrew Bivard, Michael Hill, Kenneth Butcher
BACKGROUND AND PURPOSE: In the ESCAPE trial (Endovascular Treatment for Small Core and Anterior Circulation Proximal Occlusion with Emphasis on Minimizing CT to Recanalization Times), patients with large vessel occlusions and small infarct cores identified with computed tomography (CT)/CT angiography were randomized to endovascular therapy or standard of care. CT perfusion (CTP) was obtained in some cases but was not used to select patients. We tested the hypothesis that patients with penumbral CTP patterns have higher rates of good clinical outcome...
May 8, 2018: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/29735758/the-impact-of-active-metabolism-on-chlamydia-trachomatis-elementary-body-transcript-profile-and-infectivity
#14
Scott Grieshaber, Nicole Grieshaber, Hong Yang, Briana Baxter, Ted Hackstadt, Anders Omsland
Bacteria of the genus Chlamydia include the significant human pathogens C. trachomatis and C. pneumoniae All Chlamydiae are obligate intracellular parasites that depend on infection of a host cell and transition through a biphasic developmental cycle. Following host cell invasion by the infectious Elementary Body (EB), the pathogen transitions to the replicative but non-infectious Reticulate Body (RB). Differentiation of the RB back to the EB is essential to generate infectious progeny. While the EB form has historically been regarded as metabolically inert, maintenance of infectivity during incubation with specific nutrients has revealed active maintenance of the infectious phenotype...
May 7, 2018: Journal of Bacteriology
https://www.readbyqxmd.com/read/29733002/temporary-crate-opening-procedure-affects-immediate-post-opening-piglet-mortality-and-sow-behaviour
#15
R L King, E M Baxter, S M Matheson, S A Edwards
Producers are interested in utilising farrowing systems with reduced confinement to improve sow welfare. However, concerns of increased mortality may limit commercial uptake. Temporary confinement systems utilise a standard crate which is opened 3 to 7 days postpartum, providing protection for neonatal piglets at their most vulnerable age and later increased freedom of movement for sows. However, there is anecdotal evidence that piglet mortality increases immediately after the temporary crate is opened. The current study aims were to determine if piglet mortality increases post-opening, to trial different opening techniques to reduce post-opening piglet mortality and to identify how the different opening techniques influence sow behaviour...
May 7, 2018: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29732253/digitization-protocol-for-scoring-reproductive-phenology-from-herbarium-specimens-of-seed-plants
#16
Jennifer M Yost, Patrick W Sweeney, Ed Gilbert, Gil Nelson, Robert Guralnick, Amanda S Gallinat, Elizabeth R Ellwood, Natalie Rossington, Charles G Willis, Stanley D Blum, Ramona L Walls, Elspeth M Haston, Michael W Denslow, Constantin M Zohner, Ashley B Morris, Brian J Stucky, J Richard Carter, David G Baxter, Kjell Bolmgren, Ellen G Denny, Ellen Dean, Katelin D Pearson, Charles C Davis, Brent D Mishler, Pamela S Soltis, Susan J Mazer
Premise of the Study: Herbarium specimens provide a robust record of historical plant phenology (the timing of seasonal events such as flowering or fruiting). However, the difficulty of aggregating phenological data from specimens arises from a lack of standardized scoring methods and definitions for phenological states across the collections community. Methods and Results: To address this problem, we report on a consensus reached by an iDigBio working group of curators, researchers, and data standards experts regarding an efficient scoring protocol and a data-sharing protocol for reproductive traits available from herbarium specimens of seed plants...
February 2018: Applications in Plant Sciences
https://www.readbyqxmd.com/read/29728759/effectiveness-of-gabapentin-as-a-postoperative-analgesic-in-children-undergoing-appendectomy
#17
Katherine J Baxter, Jennifer Hafling, Jennifer Sterner, Adarsh U Patel, Helen Giannopoulos, Kurt F Heiss, Mehul V Raval
PURPOSE: Though gabapentin is increasingly used as a perioperative analgesic, data regarding effectiveness in children are limited. The purpose of this study was to evaluate gabapentin as a postoperative analgesic in children undergoing appendectomy. METHODS: A 12-month retrospective review of children undergoing appendectomy was performed at a two-hospital children's institution. Patients receiving gabapentin (GP) were matched (1:2) with patients who did not receive gabapentin (NG) based on age, sex and appendicitis severity...
May 4, 2018: Pediatric Surgery International
https://www.readbyqxmd.com/read/29726587/comparative-genomics-of-pseudomonas-syringae-reveals-convergent-gene-gain-and-loss-associated-with-specialization-onto-cherry-prunus-avium
#18
Michelle T Hulin, Andrew D Armitage, Joana G Vicente, Eric B Holub, Laura Baxter, Helen J Bates, John W Mansfield, Robert W Jackson, Richard J Harrison
Genome-wide analyses of the effector- and toxin-encoding genes were used to examine the phylogenetics and evolution of pathogenicity amongst diverse strains of Pseudomonas syringae causing bacterial canker of cherry (Prunus avium), including pathovars P. syringae pv morsprunorum (Psm) races 1 and 2, P. syringae pv syringae (Pss) and P. syringae pv avii. Phylogenetic analyses revealed Psm races and P. syringae pv avii clades were distinct and were each monophyletic, whereas cherry-pathogenic strains of Pss were interspersed amongst strains from other host species...
May 4, 2018: New Phytologist
https://www.readbyqxmd.com/read/29725960/towards-portable-large-scale-image-processing-with-high-performance-computing
#19
REVIEW
Yuankai Huo, Justin Blaber, Stephen M Damon, Brian D Boyd, Shunxing Bao, Prasanna Parvathaneni, Camilo Bermudez Noguera, Shikha Chaganti, Vishwesh Nath, Jasmine M Greer, Ilwoo Lyu, William R French, Allen T Newton, Baxter P Rogers, Bennett A Landman
High-throughput, large-scale medical image computing demands tight integration of high-performance computing (HPC) infrastructure for data storage, job distribution, and image processing. The Vanderbilt University Institute for Imaging Science (VUIIS) Center for Computational Imaging (CCI) has constructed a large-scale image storage and processing infrastructure that is composed of (1) a large-scale image database using the eXtensible Neuroimaging Archive Toolkit (XNAT), (2) a content-aware job scheduling platform using the Distributed Automation for XNAT pipeline automation tool (DAX), and (3) a wide variety of encapsulated image processing pipelines called "spiders...
May 3, 2018: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
https://www.readbyqxmd.com/read/29723828/structural-neural-predictors-of-farsi-english-bilingualism
#20
Visar Berisha, Davis Gilton, Leslie C Baxter, Steven R Corman, Chris Blais, Gene Brewer, Scott Ruston, B Hunter Ball, Kimberly M Wingert, Beate Peter, Corianne Rogalsky
The neurobiology of bilingualism is hotly debated. The present study examines whether normalized cortical measurements can be used to reliably classify monolinguals versus bilinguals in a structural MRI dataset of Farsi-English bilinguals and English monolinguals. A decision tree classifier classified bilinguals with an average correct classification rate of 85%, and monolinguals with a rate of 71.4%. The most relevant regions for classification were the right supramarginal gyrus, left inferior temporal gyrus and left inferior frontal gyrus...
April 30, 2018: Brain and Language
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