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Alexandra Asaro, Gregory Ziegler, Cathrine Ziyomo, Owen Hoekenga, Brian Dilkes, Ivan Baxter
Plants obtain soil-resident elements that support growth and metabolism from the water- flow facilitated by transpiration and active transport processes. The availability of elements in the environment interacts with the genetic capacity of organisms to modulate element uptake through plastic adaptive responses, such as homeostasis. These interactions should cause the elemental contents of plants to vary such that the effects of genetic polymorphisms will be dramatically dependent on the environment in which the plant is grown...
October 21, 2016: G3: Genes—Genomes—Genetics
Erika E Atienzo, Susan K Baxter, Eva Kaltenthaler
OBJECTIVES: This review aims to summarise evidence on the effectiveness of interventions to prevent youth violence in Latin America. METHODS: A systematic search on 13 academic databases was conducted to locate studies evaluating a primary or secondary prevention intervention in Latin America. Studies could use any type of quantitative design to assess outcomes related to youth violence. A search of websites, references and citation searching was also carried out...
October 20, 2016: International Journal of Public Health
Jason Faulds, Jon Misskey, Joel Gagnon, Keith Baxter, Jerry Chen, Darren Klass, Joel Price, Michael Janusz
No abstract text is available yet for this article.
August 2016: Journal of Vascular Surgery
Jonathan Misskey, Jason Faulds, Ravi Sidhu, Keith Baxter, Joel Gagnon, York Hsiang
No abstract text is available yet for this article.
August 2016: Journal of Vascular Surgery
Dilraj S Grewal, Tamer H Mahmoud
A 54-year-old male developed symptomatic scleral buckle exposure 16 years after placement and presented with large conjunctival defects with fibrosed edges. Following surgical removal of the buckle elements, primary conjunctival closure could not be achieved due to significant wound tension despite undermining the conjunctival edges to mobilize the conjunctiva. A dehydrated amniotic membrane graft (Ambio5; IOP Ophthalmics, Costa Mesa, CA) was placed on the scleral bed and secured in place with fibrin sealant (TISSEEL; Baxter International, Westlake Village, CA)...
October 1, 2016: Ophthalmic Surgery, Lasers & Imaging Retina
Mark G Baxter, Maria C Alvarado
No abstract text is available yet for this article.
October 5, 2016: Anesthesiology
Julia L Marcus, Roger Baxter, Wendy A Leyden, Dharushana Muthulingam, Arnold Yee, Michael A Horberg, Daniel B Klein, William J Towner, Chun R Chao, Charles P Quesenberry, Michael J Silverberg
It is unclear whether HIV-infected individuals remain at higher risk of invasive pneumococcal disease (IPD) compared with HIV-uninfected individuals. We conducted a cohort study of HIV-infected and demographically matched HIV-uninfected adults within Kaiser Permanente Northern California during the period 1996-2011. We used Poisson models to obtain rate ratios (RRs) for incident IPD associated with HIV infection and other risk factors. Among 13,079 HIV-infected and 137,643 HIV-uninfected adults, the IPD rate per 100,000 person-years was 160 (n = 109 events) for HIV-infected and 8 (n = 75 events) for HIV-uninfected subjects, with an adjusted RR of 13...
October 2016: AIDS Patient Care and STDs
William R Clark, Francesco Garzotto, Mauro Neri, Anna Lorenzin, Marta Zaccaria, Claudio Ronco
PURPOSE: Dialysis is a highly quantitative therapy involving large volumes of both clinical and technical data. While automated data collection has been implemented for chronic dialysis, this has not been done for acute kidney injury patients treated with continuous renal replacement therapy (CRRT). METHODS: After a brief review of the fundamental aspects of electronic medical records (EMRs), a new tool designed to provide clinicians with individualized CRRT treatment data is analyzed, with emphasis on its quality assurance capabilities...
October 10, 2016: International Journal of Artificial Organs
Alberto Giacomello, Lothar Schimmele, Siegfried Dietrich, Mykola Tasinkevych
A liquid droplet placed on a geometrically textured surface may take on a "suspended" state, in which the liquid wets only the top of the surface structure, while the remaining geometrical features are occupied by vapor. This superhydrophobic Cassie-Baxter state is characterized by its composite interface which is intrinsically fragile and, if subjected to certain external perturbations, may collapse into the fully wet, so-called Wenzel state. Restoring the superhydrophobic Cassie-Baxter state requires a supply of free energy to the system in order to again nucleate the vapor...
October 17, 2016: Soft Matter
Jodie Oliver-Baxter, Lynsey Brown, Ellen McIntyre
Primary healthcare research strives for high-quality, priority-driven research to inform policy and practice. This relies on a robust and sustainable workforce to tackle complex problems faced in primary health care locally and globally. The current study investigated characteristics, experiences and career paths of the Australian primary healthcare research workforce. Thirty-seven former Research Higher Degree students from University Departments of General Practice and Rural Health completed a survey. Number of provisions for researchers and career path clarity were associated with job satisfaction...
October 14, 2016: Australian Journal of Primary Health
Melanie Baxter, Lori Erby, Debra Roter, Barbara A Bernhardt, Peter Terry, Alan Guttmacher
PURPOSE: This study aimed to identify factors that influence screening behaviors of adults with hereditary hemorrhagic telangiectasia (HHT). METHODS: Participants with a self-reported diagnosis of HHT were recruited from the HHT Foundation International, Inc.; the "HHT Awareness" Facebook group; and six HHT clinics. A cross-sectional mixed methods survey was administered to investigate the relationships among the Health Belief model constructs, the domains of illness representations, and HHT-specific screening behaviors consistent with recommended guidelines...
October 13, 2016: Genetics in Medicine: Official Journal of the American College of Medical Genetics
Aleksandra M Ochnik, Robert C Baxter
Insulin-like growth factor receptor (IGF1R) signaling as a therapeutic target has been widely studied and clinically tested. Despite the vast amount of literature supporting the biological role of IGF1R in breast cancer, effective clinical translation in targeting its activity as a cancer therapy has not been successful. The intrinsic complexity of cancer cell signaling mediated by many tyrosine kinase growth factor receptors that work together to modulate each other and intracellular downstream mediators in the cell highlights that studying IGF1R expression and activity as a prognostic factor and therapeutic target in isolation is certainly associated with problems...
November 2016: Endocrine-related Cancer
Kristin L Popp, William McDermott, Julie M Hughes, Stephanie A Baxter, Steven D Stovitz, Moira A Petit
PURPOSE: To determine differences in bone geometry, estimates of bone strength, muscle size and bone strength relative to load, in women runners with and without a history of stress fracture. METHODS: We recruited 32 competitive distance runners aged 18-35, with (SFX, n=16) or without (NSFX, n=16) a history of stress fracture for this case-control study. Peripheral quantitative computed tomography (pQCT) was used to assess volumetric bone mineral density (vBMD, mg/mm(3)), total (ToA) and cortical (CtA) bone areas (mm(2)), and estimated compressive bone strength (bone strength index; BSI, mg/mm(4)) at the distal tibia...
October 10, 2016: Bone
Selman Uluisik, Natalie H Chapman, Rebecca Smith, Mervin Poole, Gary Adams, Richard B Gillis, Tabot M D Besong, Judith Sheldon, Suzy Stiegelmeyer, Laura Perez, Nurul Samsulrizal, Duoduo Wang, Ian D Fisk, Ni Yang, Charles Baxter, Daniel Rickett, Rupert Fray, Barbara Blanco-Ulate, Ann L T Powell, Stephen E Harding, Jim Craigon, Jocelyn K C Rose, Eric A Fich, Li Sun, David S Domozych, Paul D Fraser, Gregory A Tucker, Don Grierson, Graham B Seymour
No abstract text is available yet for this article.
October 11, 2016: Nature Biotechnology
Ousseny Zerbo, Berwick Chan, Kristin Goddard, Ned Lewis, Karin Bok, Nicola P Klein, Roger Baxter
BACKGROUND/OBJECTIVE: We describe the establishment of a dynamic database linking mothers to newborns with the goal of studying vaccine safety in both pregnant women and their children and provide results of a study utilizing this database as a proof of concept. METHODS: All Kaiser Permanente Northern California (KPNC) live births and their mothers were eligible for inclusion in the pregnancy database. We used the medical record number (MRN), a unique identifier, to retrieve information about events that occurred during the pregnancy and at delivery and linked this same MRN to newborns for post-partum follow up...
October 7, 2016: Vaccine
Sang-Uk Cho, Doo-In Kim, Won Kyoung Cho, Bo Sung Shin, Myung Yung Jeong
The effects of the continuity of the surface pattern on wetting enhancement was investigated using micro-pillar and micro-hole arrays on hydrophilic and hydrophobic materials. Isolated micro-pillar arrays and continuous micro-hole arrays were prepared by a micro-scale imprinting technique using positive and negative Si molds fabricated by a conventional photolithography technique. The contact angles (CAs) and contact angle hysteresis (CAH) of the prepared surfaces were measured as a function of the surface parameter ξ, defined as the ratio of the top surface area of the microstructure to the surface area of the flat unit cell...
October 10, 2016: ACS Applied Materials & Interfaces
Fiona Webster, Jigisha Patel, Kathleen Rice, Nancy Baxter, Lawrence Paszat, Linda Rabeneck, Jill Tinmouth
Background. Audit and feedback (A/F) reports are one of the few knowledge translation activities that can effect change in physician behavior. In this study, we pilot-tested an endoscopist A/F report to elicit opinions about the proposed report's usability, acceptability and usefulness, and implications for knowledge translation. Methods. Semi-structured qualitative interviews were conducted with eleven endoscopists in Ontario, Canada. We tested an A/F report template comprising 9 validated, accepted colonoscopy quality indicators populated with simulated data...
2016: Canadian Journal of Gastroenterology & Hepatology
Suzanne D Baxter, David B Hitchcock, Julie A Royer, Albert F Smith, Caroline H Guinn
BACKGROUND: Validation studies that have directly assessed reporting accuracy for amounts eaten have provided results in various ways. OBJECTIVE: To analyze amount categories of a reporting-error-sensitive approach for insight concerning reporting accuracy for amounts eaten. DESIGN: For a cross-sectional validation study, children were observed eating school-provided breakfast and lunch, and randomized to one of eight 24-hour recall conditions (two retention intervals [short and long] crossed with four prompts [forward, meal name, open, and reverse])...
October 5, 2016: Journal of the Academy of Nutrition and Dietetics
Atanu K Metya, Jayant K Singh, Florian Müller-Plathe
In this work, we address the nucleation behavior of a supercooled monatomic cylindrical water droplet on nanoscale textured surfaces using molecular dynamics simulations. The ice nucleation rate at 203 K on graphite based textured surfaces with nanoscale roughness is evaluated using the mean fast-passage time method. The simulation results show that the nucleation rate depends on the surface fraction as well as the wetting states. The nucleation rate enhances with increasing surface fraction for water in the Cassie-Baxter state, while contrary behavior is observed for the case of Wenzel state...
September 29, 2016: Physical Chemistry Chemical Physics: PCCP
Yvonne Bombard, Linda Rozmovits, Anne Sorvari, Corinne Daly, June C Carroll, Erin Kennedy, Linda Rabeneck, Nancy N Baxter
PURPOSE: Population-based reflex testing of colorectal tumors can identify individuals with Lynch syndrome (LS), but there is debate regarding the type of patient discretion such a program warrants. We examined health-care providers' views and experiences to inform the design of a reflex-testing program and their perspectives regarding an opt-out option. METHODS: We interviewed providers managing LS or colorectal cancer patients, including surgeons, genetic counselors, oncologists, primary-care physicians, and gastroenterologists...
October 6, 2016: Genetics in Medicine: Official Journal of the American College of Medical Genetics
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