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https://www.readbyqxmd.com/read/29136948/gastroprotective-effect-and-mode-of-action-of-methanol-extract-of-sphenodesme-involucrata-var-paniculata-c-b-clarke-munir-lamiaceae-leaves-on-experimental-gastric-ulcer-models
#1
Puthanpura Sasidharan Sreeja, Karuppusamy Arunachalam, Sathyanarayanan Saikumar, Muniyandi Kasipandi, Sivaraj Dhivya, Rajan Murugan, Thangaraj Parimelazhagan
Sphenodesme involucrata var. paniculata (C. B. Clarke) Munir, endemic to South Asia, is used by tribal for alleviation from abdominal disorders, inflammation and body pain. However, the gastroprotective properties of this species have not yet been studied. The leaves of S. involucrata were extracted by Soxhlet extraction using different solvents successively and the extracts were analyzed for antioxidant and anti-Helicobacter pylori activities using different in vitro assays. The chemical composition of methanol extract of S...
November 9, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29135497/pancreatic-chymotrypsin-activity-rather-than-amylase-level-better-predicts-postoperative-pancreatic-fistula
#2
Suguru Yamashita, Takeaki Ishizawa, Kazuhiro Mori, Kazuteru Monden, Yugo Kuriki, Mako Kamiya, Junichi Kaneko, Nobuhisa Akamatsu, Junichi Arita, Yoshihiro Sakamoto, Kiyoshi Hasegawa, Yasuteru Urano, Norihiro Kokudo
OBJECTIVE: To assess the predictive value of chymotrypsin activity in pancreatic juice on clinically relevant postoperative pancreatic fistula (CR-POPF) after pancreatic resection, since pancreatic peptidases rather than glycolytic enzymes play a pivotal role in causing tissue damage due to pancreatic leakage. BACKGROUND: The risk of CR-POPF has been estimated based on amylase level in abdominal drainage fluid. METHODS: Eighty-one consecutive patients underwent pancreatoduodenectomy, and postoperative pancreatic juice and drainage fluids were collected for 14 days...
November 13, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/29135026/sensory-and-flavor-characteristics-of-tomato-juice-from-garden-gem-and-roma-tomatoes-with-comparison-to-commercial-tomato-juice
#3
Yaozhou Zhu, Charles A Sims, Harry J Klee, Paul J Sarnoski
The objective of this study was to characterize the flavor of a premium Florida tomato variety that has significant potential for producing a high quality processed juice product. A high-quality Florida plum tomato variety (Garden Gem), and a typical grocery-store plum tomato variety (Roma) were thermally processed into tomato juices without any additives. The 2 pilot products and a popular commercially available tomato juice (low sodium with sugar and flavor added) were compared using sensory evaluation and instrumental analysis...
November 14, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/29131970/aloe-barbadensis-miller-versus-silver-sulfadiazine-creams-for-wound-healing-by-secondary-intention-in-dogs-and-cats-a-randomized-controlled-study
#4
Dario Drudi, Debora Tinto, Davide Ferranti, Federico Fiorelli, Mara Dal Pozzo, Ombretta Capitani
The objective of this study was to compare the effectiveness of the topical application of Aloe barbadensis Miller (juice and fresh gel) to skin wounds, in dogs and cats, with that of topically applied silver sulfadiazine cream. The sample included 16 patients with cutaneous wounds (13 dogs and three cats) that were divided into three groups. Aloe vera "juice" and "fresh gel" were applied for groups I and II, respectively, while silver sulfadiazine was applied for the control group III. In order to evaluate the healing of wounds, the following parameters were taken into consideration: the percentage of wound shrinkage, the healing time and the macroscopic appearance of the scarring process...
October 31, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/29130542/safety-evaluation-of-p-synephrine-following-15%C3%A2-days-of-oral-administration-to-healthy-subjects-a-clinical-study
#5
Mohd Shara, Sidney J Stohs, Mahmoud M Smadi
Extracts of bitter orange (BOE, Citrus aurantium L.) and its primary protoalkaloid p-synephrine are extensively consumed as dietary supplements. p-Synephrine is also present in foods and juices prepared from various Citrus species. The safety of p-synephrine has been questioned as a result of structural similarities with ephedrine. This study assessed the cardiovascular (stimulant) and hemodynamic effects of BOE (49 mg p-synephrine) daily given to 16 healthy subjects for 15 days in a placebo-controlled, cross-over, double-blinded study...
November 12, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/29130128/effect-of-cys-gsh-and-ph-on-mercury-release-from-tibetan-medicine-zuotai-%C3%AE-hgs-and-%C3%AE-hgs-in-artificial-gastrointestinal-juices
#6
Zhiyuan Zheng, Ming Zhang, Yuancan Xiao, Lixin Wei, Cen Li
Zuotai, also named as "gTso thal", a known Tibetan medicinal mixture containing insoluble cubic crystal mercuric sulfide (β-HgS), has been used to treat diseases with long history. The mercury release ratio from Zuotai in gastrointestinal environment is one determinant factor for its bioavailability and biological effect. However, the information is still scarce now. Therefore, the study was designed to investigate the effect of sulfhydryl biomolecules [L-cysteine (Cys) and glutathione (GSH)] and pH on mercury dissociation from Zuotai, β-HgS, and hexagonal crystal mercuric sulfide (α-HgS) in artificial gastrointestinal juices or pure water with a 1:100 solid-liquid ratio...
November 12, 2017: Biological Trace Element Research
https://www.readbyqxmd.com/read/29128589/formulation-and-statistical-optimization-of-gastric-floating-alginate-oil-chitosan-capsules-loading-procyanidins-in-vitro-and-in-vivo-evaluations
#7
Rencai Chen, Xiaomin Guo, Xuecong Liu, Haiming Cui, Rui Wang, Jing Han
The aim of the present work was to develop gastric floating capsules containing oil-entrapped beads loading procyanidins. The floating beads were prepared by ionotropic gelation method using sodium alginate, CaCl2 and chitosan. The effect of three independent parameters (concentration of sodium alginate, CaCl2 and chitosan) on entrapment efficiency were analyzed by Box-Behnken design. The floating beads were evaluated for surface morphology, particle size, density, entrapment efficiency, buoyancy, release behavior in vitro and floating ability in vivo...
November 8, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29125915/a-pilot-study-investigating-reactive-oxygen-species-production-in-capillary-blood-after-a-marathon-and-the-influence-of-an-antioxidant-rich-beetroot-juice
#8
Tom Clifford, Amy Bowman, Tess Capper, Dean M Allerton, Emma Foster, Mark Birch-Machin, Georg Lietz, Glyn Howatson, Emma J Stevenson
We report that reactive oxygen species (ROS), as measured in capillary blood taken from the finger-tip, increased after a marathon (+128% P < 0.01; ES = 1.17), indicating that this collection method might be useful for measuring ROS in field settings. However, mitochondrial DNA damage remained unchanged. Beetroot juice, taken before and after exercise, was unable to mitigate exercise induced-ROS production, questioning its use an antioxidant rich-food.
November 10, 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/29125623/encapsulation-of-lactobacillus-casei-into-calcium-pectinate-chitosan-beads-for-enteric-delivery
#9
Aigerim Bepeyeva, Joao M S de Barros, Hanady Albadran, Aitbek K Kakimov, Zhaynagul Kh Kakimova, Dimitris Charalampopoulos, Vitaliy V Khutoryanskiy
Gel beads were prepared by extrusion of various types of pectin into 0.15 M calcium chloride. Size, morphology, and textural properties of 3 types of beads were evaluated and it was established that the use of 3 w/v % amidated pectin provides the optimal characteristics suitable for encapsulation of live bacteria. Lactobacillus casei NCIMB 30185 (PXN37) was encapsulated into calcium pectinate gel through the extrusion of a live bacteria dispersion in 3 w/v % pectin into a solution of calcium chloride. The capsules were then additionally coated with chitosan...
November 10, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/29124773/consumption-of-orange-fermented-beverage-improves-antioxidant-status-and-reduces-peroxidation-lipid-and-inflammatory-markers-in-healthy-humans
#10
Blanca Escudero-López, Ángeles Ortega, Isabel Cerrillo, María-Rosario Rodríguez-Griñolo, Rocío Muñoz-Hernández, Hada C Macher, Franz Martín, Dámaso Hornero-Méndez, Pedro Mena, Daniele Del Rio, María-Soledad Fernández-Pachón
BACKGROUND: Alcoholic fermentation of fruits has generated novel products with high concentrations of bioactive compounds and moderate alcohol content. The aim of this study was to evaluate the potential effect on cardiovascular risk factors of the regular consumption by healthy humans of a beverage obtained by alcoholic fermentation and pasteurization of orange juice. RESULTS: Thirty healthy volunteers were enrolled in a randomized controlled study. The experimental group (n=15) drank 500 mL orange beverage (OB) day(-1) for 2 weeks (intervention phase), followed by a 3-week washout phase...
November 9, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29124370/popular-weight-loss-strategies-a-review-of-four-weight-loss-techniques
#11
REVIEW
Jonathan Obert, Michelle Pearlman, Lois Obert, Sarah Chapin
PURPOSE OF REVIEW: The purpose of this paper is to review the epidemiology of obesity and the most recent literature on popular fad diets and exercise regimens that are used for weight loss. The weight loss plans that will be discussed in this article include juicing or detoxification diets, intermittent fasting, the paleo diet, and high intensity training. RECENT FINDINGS: Despite the growing popularity of fad diets and exercise plans for weight loss, there are limited studies that actually suggest these particular regimens are beneficial and lead to long-term weight loss...
November 9, 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/29121900/synergistic-gastroprotective-activity-of-methanolic-extract-of-a-mixture-of-melastoma-malabathricum-and-muntingia-calabura-leaves-in-rats
#12
Siti Zawanah Halim, Zainul Amiruddin Zakaria, Maizatul Hasyima Omar, Norhafizah Mohtarrudin, Ikarastika Rahayu Abdul Wahab, Muhammad Nazrul Hakim Abdullah
BACKGROUND: Melastoma malabathricum L. (family Melastomaceae; MM) and Muntingia calabura L. (family Elaeocarpaceae; MC) have been separately reported to possess gastroprotective activity. In an attempt to develop a pharmaceutical product with antiulcer potential, the synergistic gastroprotective activity of methanolic extract of a mixture of MM and MC (MMMC) at various ratios was evaluated in rat models. METHODS: Rats were pre-treated orally with 2% Tween 80 (vehicle), 100 mg/kg ranitidine (reference drug) or MMMC (ratios of 1:1, 1:3 and 3:1 (v/v); doses of 15, 150 or 300 mg/kg) and then subjected to the ethanol-induced gastric ulcer or pyloric ligation assays...
November 9, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29120804/comparison-of-consecutive-harvests-versus-blending-treatments-to-produce-lower-alcohol-wines-from-cabernet-sauvignon-grapes-impact-on-polysaccharide-and-tannin-content-and-composition
#13
Olaf J Schelezki, Paul A Smith, Ana Hranilovic, Keren A Bindon, David W Jeffery
A changing climate has led to winegrapes being harvested with increased sugar levels and at greater risk of berry shrivel. A suggested easy-to-adopt strategy to manage the associated rising wine alcohol levels is the pre-fermentative substitution of juice with either "green harvest wine" or water. Our study investigates the effects of this approach on Vitis vinifera L. cv. Cabernet Sauvignon wine quality attributes. Wines were also made from fruit collected at consecutive earlier harvest time points to produce wines comparable in alcohol to the substituted wines...
April 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29120795/correlation-of-lithium-bioaccessibility-from-tea-camellia-sinensis-l-with-tea-type-and-consumption-habits
#14
Umran Seven Erdemir, Seref Gucer
In this study, the total contents, leachability into tea infusions, and bioaccessibility of lithium from black, Earl Grey, and green teas were evaluated by inductively coupled plasma mass spectrometry. Leachabilities were evaluated after infusion for 2, 5, or 10min. Bioaccessibility was determined in vitro under simulated stomach and intestinal digestion conditions. Addition of lemon juice, sugar, or milk for consumption, and calcium, tannic acid, and citric acid as additives were evaluated to determine if they affected bioaccessibility of lithium from black tea...
April 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29120375/disaccharides-influence-on-volatiles-and-phenolics-of-sour-cherry-juice
#15
Emil Zlatić, Anita Pichler, Mirela Kopjar
The food industry is continuously developing ingredients, processing methods and packaging materials to improve the quality of fruit products. The aim of this work was to study the effect of sugars, a common ingredient in the food industry, on phenolics and volatiles of sour cherry juice. Sucrose, trehalose and maltose chemical isomers were chosen for this investigation. All sugars influenced the evaluated parameters. Samples with maltose addition had lower, while samples with sucrose and trehalose addition had higher anthocyanin content than the control sample...
November 9, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29119998/development-of-a-computationally-designed-polymeric-adsorbent-specific-for-mycotoxin-patulin
#16
Elena V Piletska, Demi Pink, Kal Karim, Sergey A Piletsky
Patulin is a toxic compound which is found predominantly in apples affected by mould rot. Since apples and apple-containing products are a popular food for the elderly, children and babies, the monitoring of the toxin is crucial. This paper describes a development of a computationally-designed polymeric adsorbent for the solid-phase extraction of patulin, which provides an effective clean-up of the food samples and allows the detection and accurate quantification of patulin levels present in apple juice using conventional chromatography methods...
November 9, 2017: Analyst
https://www.readbyqxmd.com/read/29119719/a-mhealth-randomized-controlled-trial-to-reduce-sugar-sweetened-beverage-intake-in-preschool-aged-children
#17
B T Nezami, D S Ward, L A Lytle, S T Ennett, D F Tate
BACKGROUND: Sugar-sweetened beverages and maternal weight are strong drivers of child obesity, but few studies have targeted these risk factors as an obesity prevention strategy in children. OBJECTIVE: The objective of this study was to test the efficacy of a smartphone-delivered intervention to reduce parent-provided sugar-sweetened beverage and juice (SSB/juice) consumption among children ages 3-5 and maternal weight. METHODS: Mothers with overweight or obesity, who had a child ages 3-5 that consumed at least 12 fl...
November 8, 2017: Pediatric Obesity
https://www.readbyqxmd.com/read/29118933/prevalence-of-cytotoxin-associated-genes-of-helicobacter-pylori-among-iranian-gerd-patients
#18
Aref Shavalipour, Habib Malekpour, Hossein Dabiri, Hossein Kazemian, Homayon Zojaji, Mahboube Bahroudi
Aim: Since the impact of H. pylori and its virulence is not clear in GERD, this study aimed to evaluate the prevalence of cag A and cag E gens of H. pylori among Iranian GERD patients. Background: Gastroesophageal reflux disease (GERD) is defined as a condition of reflux the stomach juice by low pH causes tissue damage. Helicobacter pylori may or may not influence the GERD; however, it is unclear. Methods: This study was a case-control study performed on patients with GERD who underwent upper gastrointestinal endoscopy at Taleghani Hospital of Tehran, Iran...
2017: Gastroenterology and Hepatology From Bed to Bench
https://www.readbyqxmd.com/read/29117079/integration-of-data-to-establish-a-standard-operating-procedure-for-the-diabetic-patient-undergoing-hyperbaric-oxygen-therapy
#19
Katherine George, Dianne Ross, Lynn Rowe
PURPOSE: The purpose of this study was to describe occurrences of hypoglycemia in the diabetic population undergoing hyperbaric oxygen therapy (HBOT). We also examined 2 secondary aims: link industry standards for management of hypoglycemia in the general diabetic population to the HBOT environment; and integrate HBOT data into an electronic health record system, as patients transition across inpatient and outpatient services and settings. DESIGN: A retrospective, descriptive study...
November 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/29115900/preparation-characterization-and-antitumor-activity-evaluation-of-apigenin-nanoparticles-by-the-liquid-antisolvent-precipitation-technique
#20
Weiwei Wu, Yuangang Zu, Li Wang, Lingling Wang, Huimei Wang, Yuanyuan Li, Mingfang Wu, Xiuhua Zhao, Yujie Fu
The present work aimed to apply the liquid antisolvent precipitation (LAP) method for preparing the apigenin nanoparticles and thereby improving the solubility and bioavailability of apigenin. The different experimental parameters on particle size were optimized through central composite design (CCD) using the Design-Expert(®) software. Under the optimum conditions, the particle size of the apigenin nanosuspension was about 159.2 nm. In order to get apigenin nanoparticles, the freeze-drying method was selected and the mannitol was used as a cryoprotectant...
November 2017: Drug Delivery
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