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https://www.readbyqxmd.com/read/29346059/fermented-extraction-of-citrus-unshiu-peel-inhibits-viability-and-migration-of-human-pancreatic-cancers
#1
Jungwhoi Lee, Jungsul Lee, Myungseung Kim, Jae Hoon Kim
Pancreatic cancer is one of the most dangerous cancers with high mortality rates. Despite continuous efforts, there has been limited improvement in its prognosis. In this study, we prepared fermented extract of Citrus unshiu peel (fCUP) from the by-product after juice processing and then examined the anticancer effects of fCUP on human pancreatic cancer cells. Treatment with fCUP inhibited the growth of human pancreatic cancer cells through induction of caspase-3 cleavage both in vitro and in vivo. Treatment with fCUP also blocked the migration of human pancreatic cancer cells through activation of intracellular signaling pathways such as MKK3/6 and P38...
January 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29345702/assessing-the-consumption-of-berries-and-associated-factors-in-the-united-states-using-the-national-health-and-nutrition-examination-survey-nhanes-2007-2012
#2
Britt M Burton-Freeman, Patricia M Guenther, Miyoung Oh, David Stuart, Helen H Jensen
Intake of berries was assessed relative to other fruit and fruit juices and total fruit intake in the U.S. population age 2 years and older using the National Health and Nutrition Examination Survey, 2007-2012. Average daily intake of total fruit was about 1 cup, and berries comprised approximately 10% of total fruit consumption. Only 18% of the population met the recommendation of at least 2 cups of fruit per day. Children ages 2 to 5 years consumed the most total fruit of which about half was juice and 4% of which was berries...
January 18, 2018: Food & Function
https://www.readbyqxmd.com/read/29345498/effects-of-blueberry-and-cranberry-consumption-on-type-2-diabetes-glycemic-control-a-systematic-review
#3
Dmup Rocha, Aps Caldas, Bp da Silva, Hh Hermsdorff, Rcg Alfenas
The metabolic effects of cranberry and blueberry consumption on glycemic control have been evaluated in vitro and in animal models as well as in human studies, although findings have not been systematically reviewed yet. Therefore, a systematic review was carried out of relevant randomized clinical trials (RCTs) in order to assess the effect of berries (blueberry and cranberry) consumption on type 2 diabetes (T2DM) glycemic control. Some evidences were also discussed on the anti-diabetic mechanisms exerted by berries polyphenols...
January 18, 2018: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/29345167/dietary-supplements-for-health-adaptation-and-recovery-in-athletes
#4
Eric S Rawson, Mary P Miles, D Enette Larson-Meyer
Some dietary supplements are recommended to athletes based on data that supports improved exercise performance. Other dietary supplements are not ergogenic per se, but may improve health, adaptation to exercise, or recovery from injury, and so could help athletes to train and/or compete more effectively. In this review, we describe several dietary supplements that may improve health, exercise adaptation, or recovery. Creatine monohydrate may improve: recovery from and adaptation to intense training, recovery from periods of injury with extreme inactivity, cognitive processing, and reduce severity of or enhance recovery from mild traumatic brain injury (mTBI)...
January 18, 2018: International Journal of Sport Nutrition and Exercise Metabolism
https://www.readbyqxmd.com/read/29343201/the-impact-of-blackcurrant-juice-on-attention-mood-and-brain-wave-spectral-activity-in-young-healthy-volunteers
#5
A W Watson, E J Okello, H J Brooker, S Lester, G J McDougall, K A Wesnes
There is a growing body of evidence from randomized controlled trials which indicates that consumption of berries has a positive effect upon the cognitive function of healthy adults. It has been recommended that studies combining cognitive and physiological measures be undertaken in order to strengthen the evidence base for the putative effects of flavonoid consumption on cognitive outcomes. This pilot study utilized a randomized, double-blind and placebo controlled crossover design to assess the influence of the acute administration of anthocyanin-rich blackcurrant juice, standardized at 500 mg of polyphenols, on mood and attention...
January 17, 2018: Nutritional Neuroscience
https://www.readbyqxmd.com/read/29341026/trends-and-correlates-of-frequency-of-fruit-and-vegetable-consumption-2007-to-2014
#6
Cynthia K Colapinto, John Graham, Sylvie St-Pierre
BACKGROUND: Eating fruit and vegetables is recommended as part of a healthy diet. This study describes trends in the frequency of fruit and vegetable consumption in Canada, the contribution of fruit juice to these trends, and correlates of the frequency of fruit and vegetable consumption. DATA AND METHODS: The data are from the annual Canadian Community Health Survey for the 2007-to-2014 period and pertain to the household population aged 12 or older. Weighted frequencies and cross-tabulations were used to estimate the average frequency of fruit and vegetable consumption by socio-demographic characteristics and body mass index, age-standardized to the 2014 Canadian population...
January 17, 2018: Health Reports
https://www.readbyqxmd.com/read/29340656/antagonistic-effect-of-saccharomyces-cerevisiae-ktp-and-issatchenkia-occidentalis-apc-on-hyphal-development-and-adhesion-of-candida-albicans
#7
K Lohith, K A Anu-Appaiah
The morphological transition from yeast to a hyphal form, as well as the adhesion capability to the gastrointestinal tract, are implicated virulent determinant in Candida albicans and could be potential targets for prevention of the opportunistic pathogen. Based on this rationale, two yeast strains Saccharomyces cerevisiae KTP and Issatchenkia occidentalis ApC along with reference strain Saccharomyces boulardii NCDC 363 were screened for the probiotic potential. Characters like pH, temperature, bile, simulated gastrointestinal juice tolerance tests, and Caco-2 cell line adhesion assay were determined in the present study...
January 11, 2018: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/29339307/anticoccidial-activity-of-fruit-peel-of-punica-granatum-l
#8
Shazia Ahad, Syed Tanveer, Tauseef Ahmad Malik, Irshad Ahmad Nawchoo
In the interests of food safety and public health, plants and their compounds are now re-emerging as an alternative approach to treat parasitic diseases. Here, we studied the anticoccidial effect of different solvent extracts of the fruit peel of Punica granatum-a commercial waste from pomegranate juice industries. The hope underlying these experiments was to find a sustainable natural product for controlling coccidiosis. The plant extracts were prepared using solvents of different polarity. Acute oral toxicity study was first carried out to see the safety of crude extracts...
January 12, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29339202/an-in-situ-pilot-study-to-investigate-the-native-clinical-resistance-of-enamel-to-erosion
#9
Francesca Mullan, Rupert S Austin, Charles R Parkinson, David W Bartlett
OBJECTIVES: To investigate the differences in susceptibility of the surface of native and polished enamel to dietary erosion using an in-situ model. METHODS: Thirty healthy volunteers (n = 10 per group) wore mandibular appliances containing 2 native and 2 polished enamel samples for 30 minutes after which, the samples were exposed to either an ex vivo or in vivo immersion in orange juice for 5, 10 or 15 minutes and the cycle repeated twice with an hour's interval between them...
January 12, 2018: Journal of Dentistry
https://www.readbyqxmd.com/read/29339109/bitter-gourd-reduces-elevated-fasting-plasma-glucose-levels-in-an-intervention-study-among-prediabetics-in-tanzania
#10
Michael B Krawinkel, Christine Ludwig, Mark E Swai, Ray-Yu Yang, Kwok Pan Chun, Sandra D Habicht
ETHNOPHARMACOLOGICAL RELEVANCE: Impaired glucose tolerance and diabetes mellitus have become major health issues even in non-industrialized countries. As access to clinical management is often poor, dietary interventions and alternative medicines are required. For bitter gourd, Momordica charantia L., antidiabetic properties have been claimed. AIM OF THE STUDY: The main objective of the intervention study was to assess antidiabetic effects of daily bitter gourd consumption of 2...
January 12, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29338217/unprecedented-synergistic-effects-of-nanoscale-nutrients-on-growth-productivity-of-sweet-sorghum-sorghum-bicolor-l-moench-and-nutrient-biofortification
#11
Naseeruddin Ramapuram, Sumathi V, Nvkv Prasad Tollamadugu, P Sudhakar, Chandrika V, Balam Ravindra Reddy
Evidence based synergistic effects of nanoscale materials (size <100 nm in at least one dimension) were scantly documented in agriculture at field scale. Herein, we report for the first time on effects of nanoscale zinc oxide (n-ZnO), calcium oxide (n-CaO) and magnesium oxide (n-MgO) on growth and productivity of sweet sorghum (Sorghum bicolor (L.) Moench). Modified sol-gel method was used to prepare nanoscale materials under study. Characterization was done using Electron microscopy (TEM & SEM), X-ray diffraction (XRD) and dynamic light scattering (DLS)...
January 16, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29337868/bacteriophage-gc1-a-novel-tectivirus-infecting-gluconobacter-cerinus-an-acetic-acid-bacterium-associated-with-wine-making
#12
Cécile Philippe, Mart Krupovic, Fety Jaomanjaka, Olivier Claisse, Melina Petrel, Claire le Marrec
The Gluconobacter phage GC1 is a novel member of the Tectiviridae family isolated from a juice sample collected during dry white wine making. The bacteriophage infects Gluconobacter cerinus, an acetic acid bacterium which represents a spoilage microorganism during wine making, mainly because it is able to produce ethyl alcohol and transform it into acetic acid. Transmission electron microscopy revealed tail-less icosahedral particles with a diameter of ~78 nm. The linear double-stranded DNA genome of GC1 (16,523 base pairs) contains terminal inverted repeats and carries 36 open reading frames, only a handful of which could be functionally annotated...
January 16, 2018: Viruses
https://www.readbyqxmd.com/read/29337351/selection-of-yeast-strains-for-tequila-fermentation-based-on-growth-dynamics-in-combined-fructose-and-ethanol-media
#13
J A Aldrete-Tapia, D E Miranda-Castilleja, S M Arvizu-Medrano, M Hernández-Iturriaga
The high concentration of fructose in agave juice has been associated with reduced ethanol tolerance of commercial yeasts used for tequila production and low fermentation yields. The selection of autochthonous strains, which are better adapted to agave juice, could improve the process. In this study, a 2-step selection process of yeasts isolated from spontaneous fermentations for tequila production was carried out based on analysis of the growth dynamics in combined conditions of high fructose and ethanol. First, yeast isolates (605) were screened to identify strains tolerant to high fructose (20%) and to ethanol (10%), yielding 89 isolates able to grow in both conditions...
January 16, 2018: Journal of Food Science
https://www.readbyqxmd.com/read/29336700/effect-of-daily-exposure-to-an-isolated-soy-protein-supplement-on-body-composition-energy-and-macronutrient-intake-bone-formation-markers-and-lipid-profile-in-children-in-colombia
#14
Wilson Mejía, Diana Córdoba, Paola Durán, Yersson Chacón, Diego Rosselli
A soy protein-based supplement may optimize bone health, support physical growth, and stimulate bone formation. This study aimed to assess the effect of a daily soy protein supplement (SPS) on nutritional status, bone formation markers, lipid profile, and daily energy and macronutrient intake in children. One hundred seven participants (62 girls), ages 2 to 9, started the study and were randomly assigned to lunch fruit juice with (n = 57, intervention group) or without (n = 50, control group) addition of 45 g (230 Kcal) of a commercial SPS during 12 months; 84 children (51 girls, 33 boys) completed the study (45 and 39 intervention and control, respectively)...
January 16, 2018: Journal of Dietary Supplements
https://www.readbyqxmd.com/read/29336243/identification-of-in-vitro-red-fluorescent-protein-with-antipathogenic-activity-from-the-midgut-of-the-silkworm-bombyx-mori-l
#15
Manjunatha Ks Gowda, Anitha Peter, Mahantesha Bn Naika, P Niranjana, P Shamprasad
Biotic stress affects all organisms, including the silkworm (Bombyx mori L.) which also has a plethora of defense mechanisms against the infecting pathogens. The midgut plays an important role as a natural barrier and source of innate immunity. The present investigation was thus undertaken to identify an antiviral red fluorescent protein formed in the midgut of the silkworm Bombyx mori L. The digestive juice from fifth instar Kolar Gold silkworm larvae was collected and subjected to 40 % ammonium sulfate precipitation and purified by gel filtration chromatography (GFC)...
January 15, 2018: Protein and Peptide Letters
https://www.readbyqxmd.com/read/29334437/a-randomized-clinical-trial-to-measure-the-erosion-protection-benefits-of-a-novel-stabilized-stannous-fluoride-dentifrice-versus-a-control-dentifrice
#16
Xinyi Zhao, Tao He, Yanyan He, Cathy Cheng, Haijing Chen
OBJECTIVES: The aim of this investigation was to assess the erosion protection ability of a novel stabilized stannous fluoride (SnF2) dentifrice and a control sodium fluoride dentifrice (NaF) using a well-credentialed human in situ model. METHODS: A novel smooth texture 0.454% stabilized SnF2 dentifrice (Crest® Pro-Health™ smooth formula) and a 0.23% NaF marketed control dentifrice with 5% potassium nitrate (Sensodyne® Pronamel®) were compared in a 10-day, single center, randomized, controlled, double-blind, two-treatment, three-period crossover in situ clinical trial...
December 2017: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/29333058/acquisition-of-a-socially-learned-tool-use-sequence-in-chimpanzees-implications-for-cumulative-culture
#17
Gillian L Vale, Sarah J Davis, Susan P Lambeth, Steven J Schapiro, Andrew Whiten
Cumulative culture underpins humanity's enormous success as a species. Claims that other animals are incapable of cultural ratcheting are prevalent, but are founded on just a handful of empirical studies. Whether cumulative culture is unique to humans thus remains a controversial and understudied question that has far-reaching implications for our understanding of the evolution of this phenomenon. We investigated whether one of human's two closest living primate relatives, chimpanzees, are capable of a degree of cultural ratcheting by exposing captive populations to a novel juice extraction task...
September 2017: Evolution and Human Behavior: Official Journal of the Human Behavior and Evolution Society
https://www.readbyqxmd.com/read/29331733/aronia-melanocarpa-fruit-juice-ameliorates-the-symptoms-of-inflammatory-bowel-disease-in-tnbs-induced-colitis-in-rats
#18
Stefka Valcheva-Kuzmanova, Atanas Kuzmanov, Vasilena Kuzmanova, Maria Tzaneva
Trinitrobenzensulfonic acid (TNBS) is commonly used to induce an experimental inflammatory bowel disease (IBD) model. Oxidative stress and inflammation have been proposed as mechanisms underlying the pathophysiology of IBD. Aronia melanocarpa fruit juice (AMFJ) is extremely rich in polyphenolic substances, mainly proanthocyanidins, flavonoids and phenolic acids. The aim of this study was to evaluate the effect of AMFJ in a rat TNBSinduced colitis model and to compare the effect of the juice with that of sulfasalazine...
January 10, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29331460/inhibition-of-shigella-sonnei-induced-epithelial-barrier-disruption-by-surface-layer-associated-proteins-of-lactobacilli-from-chinese-fermented-food
#19
Yingchun Zhang, Xiaolu Shi, Siqi Hao, Qianhui Lu, Lanwei Zhang, Xue Han, Weihong Lu
Surface-layer associated proteins (SLAP) of Lactobacillus paracasei ssp. paracasei M5-L and Lactobacillus casei Q8-L were examined to identify the functional basis for their protection within intestinal epithelial cells. The results showed that SLAP of M5-L and Q8-L remained active in a trypsin solution and retained a 45-kDa protein band, similar to that observed in controls. In contrast, under conditions of simulated gastric juice, the SLAP were partially degraded. Inhibitory effects of SLAP on adherence of Shigella sonnei to HT-29 cells were assessed with use of exclusion, competition, and replacement assays...
January 10, 2018: Journal of Dairy Science
https://www.readbyqxmd.com/read/29331107/endoscopic-full-thickness-resection-combined-with-laparoscopic-surgery
#20
Chan Gyoo Kim
Endoscopic full-thickness resection combined with laparoscopic surgery was recently developed. These procedures could be categorized as "Cut first and then suture" and "Suture first and then cut". "Cut first and then suture" includes laparoscopic and endoscopic cooperative surgery (LECS) and laparoscopy-assisted endoscopic full-thickness resection (LAEFR). Recent studies have demonstrated the safety and efficacy of LECS and LAEFR. However, these techniques are limited by the related exposure of the tumor and gastric mucosa to the peritoneal cavity and manipulation of these organs, which could lead to viable cancer cell seeding and the spillage of gastric juice into the peritoneal cavity...
January 12, 2018: Clinical Endoscopy
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