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Conor P Kerley, Eamon Dolan, Philip E James, Liam Cormican
Dietary nitrate has been shown to increase nitrate/nitrite levels and decrease blood pressure (BP) in multiple populations. There are few reports among hypertensives and these reports have provided conflicting evidence. We aimed to assess the effect of daily nitrate compared with placebo in subjects with uncontrolled hypertension (HTN). On day 0, hypertensives wore an ambulatory BP monitor (ABPM) for 24 h and blood was taken. Subjects were then randomised to 7-d nitrate-rich beetroot juice (NO3 -) (12·9 mmol nitrate) followed by 7-d nitrate-depleted beetroot juice (0·5 mmol nitrate) or vice versa...
March 2018: British Journal of Nutrition
Manuel Valenzuela, Lorena Bastias, Iván Montenegro, Enrique Werner, Alejandro Madrid, Patricio Godoy, Mario Párraga, Joan Villena
Antioxidants are known to be beneficial to health. This paper evaluates the potential chemopreventive and anticancer properties of phenolic compounds present in grape juice extracts (GJE) from Autumn Royal and Ribier varieties. The effects of these GJE on viability (SRB day assay) and metastatic potential (migration and invasion parameters) of colon cancer cell lines HT-29 and SW-480 were evaluated. The effects of GJE on two matrix metalloproteinase gene expressions (MMP2 and MMP9) were also evaluated via qRT-PCR...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
Akshay Sood, Daniel Cole, Shaheen Alanee
Acute scrotum is a urologic emergency with many aetiologies. Acute scrotum in setting of acute pancreatitis is a rare occurrence and results from an effusion of pancreatic juices into the inguinal canal along a retroperitoneal tract. Knowledge regarding the existence of this obscure condition is essential for its diagnosis. It is thus important for medical professionals, particularly internists, surgical trainees and emergency physicians, to be aware of the condition and the options for its management.
March 17, 2018: BMJ Case Reports
Soon-Sen Leow, Alice Luu, Swechhya Shrestha, K C Hayes, Ravigadevi Sambanthamurthi
Palm fruit juice (PFJ) containing oil palm phenolics is obtained as a by-product from oil palm (Elaeis guineensis) fruit milling. It contains shikimic acid, soluble fibre and various phenolic acids including p-hydroxybenzoic acid and three caffeoylshikimic acid isomers. PFJ has also demonstrated beneficial health properties in various biological models. Increasing concentrations of PFJ and different PFJ fractions were used to assess growth dynamics and possible anti-ageing properties in fruit flies (Drosophila melanogaster) genotype w1118 ...
March 14, 2018: Experimental Gerontology
Ameer Khusro, Chirom Aarti, Abdelfattah Z M Salem, German Buendía-Rodríguez, Raymundo Rene Rivas-Cáceres
The desideratum aim of the present context was to isolate a promising antagonist probiotic bacterium from fermented food item as biocontrol agent against uropathogens. Among diversified isolates evaluated for antagonistic trait, Staphylococcus succinus strain AAS2 was found to be an auspicious candidate against urinary tract infection (UTI) causing bacterial pathogens, being the most active against Staphylococcus aureus with substantial activity of 352.5 ± 5.4 AU/mL. Further, the in vitro probiotic attributes of strain AAS2 was assessed using systematic methodology...
March 14, 2018: Microbial Pathogenesis
Xabier Osteikoetxea, Márton Benke, Marta Rodriguez, Krisztina Pálóczi, Barbara W Sódar, Zsuzsanna Szvicsek, Katalin Szabó-Taylor, Krisztina V Vukman, Ágnes Kittel, Zoltán Wiener, Károly Vékey, László Harsányi, Ákos Szűcs, Lilla Turiák, Edit I Buzás
AIMS: The prognosis of patients with pancreatic cancer has remained virtually unchanged with a high mortality rate compared to other types of cancers. An earlier detection would provide a time window of opportunity for treatment and prevention of deaths. In the present study we investigated extracellular vesicle (EV)-associated potential biomarkers for pancreatic cancer by directly assessing EV size-based subpopulations in pancreatic juice samples of patients with chronic pancreatitis or pancreatic cancer...
March 14, 2018: Biochemical and Biophysical Research Communications
Jennifer Gubitosa, Vito Rizzi, Angela Lopedota, Paola Fini, Anna Laurenzana, Gabriella Fibbi, Fiorenza Fanelli, Andrea Petrella, Valentino Laquintana, Nunzio Denora, Roberto Comparelli, Pinalysa Cosma
HYPOTHESIS: The interesting properties of Gold Nanoparticles (AuNPs) make them attractive for different application fields such as cosmetology, medicine and clinical nanotechnologies. In this work a fast, easy and eco-friendly method for the AuNPs synthesis is proposed by using the Punica Granatum Juice (PGJ) with potential dermatological and cosmetic applications. The AuNPs antioxidant activity, due to the presence of phenols from the juice, and their use as booster for improving the Sun Protection Factor (SPF) in commercial sunscreen formulations, are thus expounded...
March 9, 2018: Journal of Colloid and Interface Science
Mehrdad Behnia, Courtney M Wheatley, Alberto Avolio, Bruce D Johnson
BACKGROUND: During exercise as pulmonary blood flow rises, pulmonary capillary blood volume increases and gas exchange surface area expands through distention and recruitment. We have previously demonstrated that pulmonary capillary recruitment is limited in COPD patients with poorer exercise tolerance. Hypoxia and endothelial dysfunction lead to pulmonary vascular dysregulation possibly in part related to nitric oxide related pathways. PURPOSE: To determine if increasing dietary nitrate might influence lung surface area for gas exchange and subsequently impact exercise performance...
March 13, 2018: Nitric Oxide: Biology and Chemistry
Carolina Sheng Whei Miaw, Camila Assis, Alessandro Rangel Carolino Sales Silva, Maria Luísa Cunha, Marcelo Martins Sena, Scheilla Vitorino Carvalho de Souza
Grape, orange, peach and passion fruit nectars were formulated and adulterated by dilution with syrup, apple and cashew juices at 10 levels for each adulterant. Attenuated total reflectance Fourier transform mid infrared (ATR-FTIR) spectra were obtained. Partial least squares (PLS) multivariate calibration models allied to different variable selection methods, such as interval partial least squares (iPLS), ordered predictors selection (OPS) and genetic algorithm (GA), were used to quantify the main fruits. PLS improved by iPLS-OPS variable selection showed the highest predictive capacity to quantify the main fruit contents...
July 15, 2018: Food Chemistry
Qisen Xiang, Xiufang Liu, Junguang Li, Shengnan Liu, Hua Zhang, Yanhong Bai
This work aimed to evaluate the effects of dielectric barrier discharge (DBD) plasma on inactivation of spoilage yeast Zygosaccharomyces rouxii (Z. rouxii), in apple juice. Results showed that DBD plasma treatment at 90 W for 140 s resulted in about 5-log reduction of Z. rouxii in apple juice. The levels of extracellular nucleic acids and proteins as well as contents of H2 O2 and NO2 - in yeast extract-peptone-dextrose (YPD) medium increased significantly after DBD plasma treatment at 90 W for 40-200 s...
July 15, 2018: Food Chemistry
Mark Waldron, Luke Waldron, Craig Lawlor, Adrian Gray, Jamie Highton
PURPOSE: We investigated the effects of an acute 24-h nitrate-rich beetroot juice supplement (BR) on the energy cost, exercise efficiency and blood pressure responses to intermittent walking at different gradients. METHODS: In a double-blind, cross-over design, eight participants were provided with a total of 350 ml of nitrate-rich (~ 20.5 mmol nitrate) BR or placebo (PLA) across 24 h before completing intermittent walking at 3 km/h on treadmill at gradients of 1, 5, 10, 15 and 20%...
March 15, 2018: European Journal of Applied Physiology
Noushin Rastkari, Maryam Zare Jeddi, Masud Yunesian, Reza Ahmadkhaniha
Acidic liquids such as verjuice, lemon juice and vinegar are frequently consumed in Iran. Different kinds of acidic liquids are packaged in polyethylene terephthalate (PET) and high-density polyethylene (HDPE) bottles. There is evidence indicating that phthalates can leach from PET and HDPE bottles into their contents. In this work the effect of storage time, temperature and bottle type on the migration of phthalates from packaging materials into acidic liquids is studied by analyzing the samples stored under different conditions, before storage and after 2, 4 and 6 months of storage...
December 2017: Food Technology and Biotechnology
Natalya Cherno, Sophya Osolina, Oleksandra Nikitina
One of the methods for curing obesity is the inclusion of some substances with the antilipase activity in the diet and thus reducing the uptake of fat components from food. The aim of this research is to provide a stabilized form of lipase inhibitor by immobilization of enzyme on the biopolymers from Agaricus bisporus cell walls. The phenolic compounds extracted from the rapeseed were considered as the lipase inhibitor. The activity of the inhibitor was considerably reduced in the gastric juice, as well as at temperatures above 37 °C and during its storage, which determined the suitability of the inhibitor for stabilization on the matrix...
December 2017: Food Technology and Biotechnology
Oksana V Bocharova, Sentyabrina P Reshta, Maiia Y Bocharova, Vasiliy I Eshtokin
BACKGROUND: Organoleptic properties, and positive health effect on consumers, both justify the importance of the determination of apple juice authenticity, in respect of retail and wholesale trade networks worldwide. RESULTS: Adulteration of apple juice through dilution with water, and with ascorbic acid has been determined. It has been demonstrated that polarization curves of platinum electrode (Pt) in apple juice are useful for undeclared antioxidant determination, due to the movement of the polarization curve to the left, by 200 mV, when ascorbic acid was added...
March 13, 2018: Journal of the Science of Food and Agriculture
Parmiss Mojir Shaibani, Hashem Rajab Etayash, Keren Jiang, Amirreza Sohrabi, Mahtab Hassanpourfard, Selvaraj Naicker, Mohtada Sadrzadeh, Thomas Thundat
The growing need to prevent pathogen outbreaks is irrefutable in the case of the food industry. Early detection in products, especially beverages, contaminated with bacterial strains is vital to avoid infected foods from reaching the consumer. If E. coli is pesent in such foods, it can cause infections. It can also be an indicator of the existence of other harmful coliforms. In this study, we have investigated the detection of Escherichia coli (E. coli) in orange juice using a portable nanofiber-light addressable potentiometric sensor (NF-LAPS)...
March 13, 2018: ACS Sensors
Ron Shaoul, Dalia Moati, Betty Schwartz, Yulia Pollak, Igor Sukhotnik
BACKGROUND/AIMS: Several studies have demonstrated the antimicrobial, antihelminthic, and antioxidant potential of the active ingredients of pomegranate (PMG) extracts, suggesting their preventive and curative role in several gastrointestinal disorders. In the present study, the authors evaluated the effects of oral PMG supplementation on intestinal structural changes, enterocyte proliferation, and apoptosis during methotrexate (MTX)-induced intestinal damage in a rat. METHODS: Male rats were divided into 4 experimental groups: control rats; CONTR-PMG rats were treated with oral PMG given by gavage once a day 72 hours before and 72 hours following vehicle injection; MTX rats were treated with single dose of methotrexate; and MTX-PMG rats were treated with oral PMG following injection of MTX...
March 13, 2018: Journal of the American College of Nutrition
Rabia Iqbal, Tahir Zahoor, Nuzhat Huma, Amer Jamil, Gülhan Ünlü
Longevity of probiotic is the main concern for getting maximum benefits when added in food product. Bifidobacterium, a probiotic, tends to lose its viability during gastrointestinal track (GIT) transit and storage of food. Their viability can be enhanced through microencapsulation technology. In this study, Bifidobacterium bifidum (B. bifidum) ATCC 35914 was encapsulated by using two experimental plans. In the first plan, chitosan (CH) at 0.6, 0.8, and 1.0% and sodium alginate (SA) at 4, 5, and 6% were used...
March 12, 2018: Probiotics and Antimicrobial Proteins
Sara J White, Emma L Carran, Andrew N Reynolds, Jillian J Haszard, Bernard J Venn
Background: The consumption of large amounts of fructose from added sugars results in the hepatic production and export of uric acid into the circulation. Objective: Our aim was to test whether fructose present in fruit is of sufficient quantity or in a form that will increase uric acid concentration. Design: Seventy-three participants were randomly assigned to 1 of 3 groups to ingest small (205 g) and large (410 g) servings of apple segments, small (170 mL) and large (340 mL) servings of apple juice, or a glucose and a fructose control beverage...
February 1, 2018: American Journal of Clinical Nutrition
Wenjing Wan, Baojun Xu
BACKGROUND: We aimed to develop a beverage using beta-glucan and whey protein isolate (WPI). Furthermore, we evaluated the sensory attributes and changes of the physiochemical properties (pH value, total acidity, total soluble solids, sugar-acid ratio, color, viscosity, turbidity, and browning index) of the beverage during 48-hour storage by comparison with the commercial product and blank sample. RESULTS: The developed beverage had similar sweetness, smoothness, and overall acceptance as those of the commercial and blank samples...
March 12, 2018: Journal of the Science of Food and Agriculture
David Bender, Jeremy R Townsend, William Vantrease, Autumn C Marshall, Ruth N Henry, Stephen Heffington, Kent D Johnson
The purpose of this study was to examine the effects of acute beetroot juice (BR) administration on repeated sprint performance and isometric force production in adolescent males. Twelve male adolescents (16.8 ± 1.0 yrs; 178.8 ± 9.2 cm; 74.8 ± 12.5 kg; peak height velocity: 2.53 ± 1.2 yrs) participated in this double-blind, placebo-controlled, crossover designed study. Participants consumed 2 x 70 mL of BR (~12.9 mmol NO3¯; Beet It Sport®) or a nitrate-depleted placebo (PL) 2.5 hours prior to performing isometric mid-thigh pulls (IMTP) and four repeated 20-second Wingate sprints (S1-S4) interspersed with 4 minutes of rest...
March 10, 2018: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
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