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https://www.readbyqxmd.com/read/28547073/the-influence-of-low-intensity-he-ne-laser-on-the-wound-healing-in-diabetic-rats
#1
Maha Eissa, Wasil H M Salih
The low-level laser irradiation at certain wavelengths is reported to facilitate the healing process of diabetic wounds. Thus, this study carried out to look for the suitable laser parameters that could speed up the healing process. Fourteen healthy male and female rats were used in which a circular wound with a diameter of 2.5 ± 0.2 cm was created on the dorsum in each rat after injected them with alloxan to induced diabetic. They have been divided into two groups: control group (N = 7) and study group (N = 7) to conduct the study...
May 25, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28544068/interstitial-fluid-pressure-a-novel-biomarker-to-monitor-photo-induced-drug-uptake-in-tumor-and-normal-tissues
#2
Sabrina Cavin, Xingyu Wang, Matthieu Zellweger, Michel Gonzalez, Michaël Bensimon, Georges Wagnières, Thorsten Krueger, Hans-Beat Ris, Fabrizio Gronchi, Jean Y Perentes
BACKGROUND: Low-dose photodynamic therapy PDT (photoinduction) can modulate tumor vessels and enhance the uptake of liposomal cisplatin (Lipoplatin®) in pleural malignancies. However, the photo-induction conditions must be tightly controlled as overtreatment shuts down tumor vessels and enhances normal tissue drug uptake. MATERIAL AND METHODS: In a pleural sarcoma and adenocarcinoma rat model (n = 12/group), we applied photoinduction (0.0625 mg/kg Visudyne®, 10 J/cm(2) ) followed by intravenous Lipoplatin® (5 mg/kg) administration...
May 22, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28538060/effect-of-low-level-laser-and-light-emitting-diode-on-inferior-alveolar-nerve-recovery-after-sagittal-split-osteotomy-of-the-mandible-a-randomized-clinical-trial-study
#3
Seyed Hasan Mohajerani, Faraj Tabeie, Mehdi Bemanali, Reza Tabrizi
PURPOSE: The major concern of sagittal split osteotomy (SSO) is the neurosensory disturbance. The authors investigated the effect of low-level laser therapy and light-emitting diode on the inferior alveolar nerve recovery after SSO. METHODS: In this double-blinded randomized clinical trial, 20 subjects with inferior alveolar nerve injury after SSO of the mandible were studied. Neurosensory recovery was assessed by 6 tests: visual analog scale (VAS), brush stroke, 2-point discrimination, contact detect detection, pinprick nociception, and thermal discrimination, and each one was performed before and after the surgery on days 1, 3, 7, 14, 60, and 180...
May 19, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28536905/efficacy-of-low-level-laser-therapy-in-management-of-symptomatic-oral-lichen-planus-a-systematic-review
#4
Sadeq Ali Al-Maweri, Butchibabu Kalakonda, Walid A Al-Soneidar, Hashem Motahir Al-Shamiri, Mohammed Sultan Alakhali, Nader Alaizari
Oral lichen planus (OLP) is a chronic inflammatory disease of unknown etiology and indefinite cure. This systematic review assessed the efficacy of low-level laser therapy in the treatment of symptomatic OLP. Electronic databases (PubMed, Scopus, and Web of Science) were searched from date of inception till and including December 2016, using various combinations of the following keywords: oral lichen planus, laser therapy, low-level laser therapy, and phototherapy. Owing to heterogeneity of data, no statistical analyses were conducted...
May 24, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28536904/efficacy-of-photobiomodulation-therapy-on-masseter-thickness-and-oral-health-related-quality-of-life-in-children-with-spastic-cerebral-palsy
#5
Maria Teresa Botti Rodrigues Santos, Karla Santos Nascimento, Simone Carazzato, Alina Oliveira Barros, Fausto Medeiros Mendes, Michele Baffi Diniz
The study aimed to evaluate the efficacy of photobiomodulation therapy (PBMT) on bilateral masseter muscle thickness and amplitude of mouth opening in children with spastic cerebral palsy (CP), and the impact on their oral health-related quality of life (OHRQOL). Three groups were included: experimental CP group (EG: n = 26 with oral complaints), positive control CP group (PCG: n = 26 without complaints), and negative control group (NCG: n = 26 without CP). In the EG, the masseter muscles on both sides were irradiated with an infrared low-level Ga-Al-As laser (λ = 808 ± 3 nm, 120 mW) using a 3 J/cm(2) energy dose per site, with a 20 s exposure time per site (spot area: 4 mm(2); irradiance: 3 W/cm(2); energy delivery per point: 2...
May 23, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28527829/graphene-oxide-nanosheets-and-d-%C3%AE-tocopheryl-polyethylene-glycol-1000-succinate-tpgs-doping-improves-biocompatibility-and-ultrafiltration-in-polyethersulfone-hollow-fiber-membranes
#6
Akshay Modi, Surendra Kumar Verma, Jayesh Bellare
Novel graphene oxide (G)-and d-α-Tocopheryl polyethylene glycol 1000 succinate (T)-doped polyethersulfone (P) hollow fiber membranes (GTP HFMs) were efficiently prepared. GTP HFMs were found to be a desirable biocompatible substrate for attachment and proliferation of human embryonic kidney-293 (HEK-293) cells. Significantly high porosity (94.58±1.1%), low contact angle (61.1±2.5°), low hemolysis (0.58% in batch mode and 0.64% in continuous mode), low terminal complement complex activation (SC5b-9 marker level ∼6...
May 12, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28525303/low-level-laser-therapy-after-wisdom-teeth-surgery-evaluation-of-immunologic-markers-secretory-immunoglobulin-a-and-lysozyme-levels-and-thermographic-examination-placebo-controlled-study
#7
Tatjana Dostalova, Veronika Kroulikova, Stepan Podzimek, Helena Jelinková
OBJECTIVE: The goal of this investigation is to analyze the effect of therapeutic low-level laser therapy (LLLT) to have a possibility to check pain and inflammation connected with surgical removal of impacted lower third molars in general anesthesia or even phobia [not accompanied by pain or fear of dental treatment, using immunologic markers-secretory immunoglobulin A (sIgA) and lysozyme]. The healing process was also monitored by infrared thermography. BACKGROUND DATA: LLLT can accelerate the proliferation phase of healing and decrease the inflammatory reaction, but the effect is not really clear...
May 16, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28523391/the-effect-of-low-level-diode-laser-on-cox-2-gene-expression-in-chronic-periodontitis-patients
#8
Snezana Pesevska, Icko Gjorgoski, Kiro Ivanovski, Nikolaos K Soldatos, Nikola Angelov
Adjunctive treatments to scaling and root planing (SRP) such as lasers, have been utilized in the treatment of chronic periodontitis, mainly aiming to suppress and eliminate the bacteria, as well as enhancing the healing response. Eighty gingival papilla biopsy samples were obtained from 60 patients diagnosed with chronic advanced periodontitis; randomly assigned to three treatment groups (n = 20), as well as 20 subjects with no periodontal disease [group A]. Group B received SRP on a single quadrant/day for four consecutive days...
May 18, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28513251/comparison-of-the-effects-of-665-nm-low-level-diode-laser-hat-versus-and-a-combination-of-665-nm-and-808nm-low-level-diode-laser-scanner-of-hair-growth-in-androgenic-alopecia
#9
Behrooz Barikbin, Zeinab Khodamrdi, Leila Kholoosi, Mohammad Reza Akhgri, Majid Haj Abbasi, Mojgan Hajabbasi, Zahra Razzaghi, Samaneh Akbarpour
BACKGROUND: This study aimed to evaluate the effectiveness of a combined set of low level diode laser scanner (665 nm and 808nm) on hair growth, and assessment of safety and effectiveness of a new laser scanner on hair growth treatment procedure in androgenic alopecia. METHODS: 90 patients (18 to 70 years) with androgenic alopecia were randomized into three groups. The first group (n=30) received 655 nm red light using laser hat, the second group (n=30) received 655 nm red laser plus 808 nm infrared laser using a laser scanner of hair growth device (with the patent number: 77733) and the third group (n=30) received no laser as the control group...
May 17, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28512727/variability-of-high-dose-melphalan-exposure-on-oral-mucositis-in-patients-undergoing-prophylactic-low-level-laser-therapy
#10
Gustavo Henrique Rodrigues, Graziella Chagas Jaguar, Fabio Abreu Alves, Andre Guollo, Vanessa Oliveira Camandoni, Aline Santos Damascena, Vladmir Claudio Cordeiro Lima
The present study outlines the clinical impact and risk factors of oral mucositis in 79 patients with multiple myeloma following high-dose melphalan for autologous transplant. All patients underwent daily prophylactic low-level indium gallium aluminum phosphate diode laser therapy (660 nm, 15 mW, 3.75 J/cm(2), 10 s per point) from the beginning of the conditioning regimen up to day +2. Oral mucositis assessments were made daily until hospital discharge. For analysis, oral mucositis was divided into two groups according to severity: group 1, patients with oral mucositis grade <III (n = 71) and group 2, patients with oral mucositis grade ≥III (n = 8)...
May 16, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28511874/photothermal-and-photodynamic-activity-of-polymeric-nanoparticles-based-on-%C3%AE-tocopheryl-succinate-raft-block-copolymers-conjugated-to-ir-780
#11
Raquel Palao-Suay, Francisco M Martin-Saavedra, María Rosa Aguilar, Clara Escudero Duch, Sergio Martín-Saldaña, Francisco J Parra-Ruiz, Nathan A Rohner, Susan N Thomas, Nuria Vilaboa, Julio San Román
The aim of this work was the generation of a multifunctional nanopolymeric system that incorporates IR-780 dye, a near-infrared (NIR) imaging probe that exhibits photothermal and photodynamic properties; and a derivate of α-tocopheryl succinate (α-TOS), a mitochondria-targeted anticancer compound. IR-780 was conjugated to the hydrophilic segment of copolymer PEG-b-polyMTOS, based on poly(ethylene glycol) (PEG) and a methacrylic derivative of α-tocopheryl succinate (MTOS), to generate IR-NP, self-assembled nanoparticles (NPs) in aqueous media which exhibit a hydrophilic shell and a hydrophobic core...
May 13, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28508243/low-level-laser-treatment-stimulates-hair-growth-via-upregulating-wnt10b-and-%C3%AE-catenin-expression-in-c3h-hej-mice
#12
Tiran Zhang, Liqiang Liu, Jincai Fan, Jia Tian, Cheng Gan, Zengjie Yang, Hu Jiao, Bing Han, Zheng Liu
This study was conducted in order to evaluate the role of low-level laser treatment (LLLT) in hair growth in C3H/HeJ mice. Healthy C57BL/6 mice were randomly divided into two groups: with and without low-level laser treatment. The skin color of each mouse was observed each day. Skin samples were collected for H&E, immunofluorescence, PCR, and western blot analysis, to observe the morphology of hair follicles and detect the expression levels of Wnt10b and β-catenin. Observation of skin color demonstrated that black pigmentation started significantly earlier in the laser group than in the control group...
May 16, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28507373/comparison-of-low-level-laser-therapy-and-interferential-current-on-post-stroke-shoulder-pain
#13
Fahmida Jan, Aamir Naeem, Arshad Nawaz Malik, Imran Amjad, Tariq Malik
The objective of the study was to compare the effects of LASER therapy and Interferential current on post stroke shoulder pain. Diagnosed patients (n=38) of post stroke shoulder pain were randomly divided into two groups i.e., LASER group (LG =20 patients) and Interferential current group (IFCG=18 patients). The variables under study were pain, satisfaction, disability, and function level before and after treatment. Improvement in pain and satisfaction level after LASER therapy was significant (p<0.001)...
May 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28505127/variability-of-dna-methylation-within-schizophrenia-risk-loci-across-subregions-of-human-hippocampus
#14
W Brad Ruzicka, Sivan Subburaju, Francine M Benes
Identification of 108 genomic regions significantly associated with schizophrenia risk by the Psychiatric Genomics Consortium was a milestone for the field, and much work is now focused on determining the mechanism of risk associated with each locus. Within these regions, we investigated variability of DNA methylation, a low-level cellular phenotype closely linked to genotype, in two highly similar cellular populations sampled from the human hippocampus, to draw inferences about the elaboration of genotype to phenotype within these loci enriched for schizophrenia risk...
May 15, 2017: Genes
https://www.readbyqxmd.com/read/28502007/high-resolution-image-stitching-as-a-tool-to-assess-tissue-level-protein-distribution-and-localization
#15
Bryan A Millis, Matthew J Tyska
High-resolution microscopy has traditionally come at the expense of field of view, resulting in suboptimal interpretation of protein distribution throughout large or complex samples. Likewise, a low-resolution microscopic approach inhibits the ability of researchers to precisely localize proteins of interest at the subcellular level. Until recently, the ability to combine the strengths of these approaches was limited and technically impractical for most laboratories to implement. Continued advances in microscope automation, sophisticated software applications, and modern workstations have enabled expansion of such combinatorial approaches to researchers outside computationally focused fields...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28501780/low-power-continuous-wave-laser-seed-irradiation-effect-on-moringa-oleifera-germination-seedling-growth-and-biochemical-attributes
#16
Urva, Hina Shafique, Yasir Jamil, Zia Ul Haq, Tamveel Mujahid, Aman Ullah Khan, Munawar Iqbal, Mazhar Abbas
Recently, laser application in agriculture has gained much attention since plant characteristics were improved significantly in response of pre-sowing seed treatment. Pre-sowing laser seed treatment effects on germination, seedling growth and mineral profile were studied in Moringa olifera. M. olifera healthy seeds were exposed to 25, 50, 75mJ low power continuous wave laser light and grown under greenhouse conditions. The seedling growth and biochemical attributes were evaluated from 10-day-old seedlings. The germination parameters (percentage, mean germination time), vigor index, seedling growth (root length, seedling length, shoot fresh weight, root fresh weight, shoot dry weight, root dry weight) enhanced considerably...
April 5, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28500856/effect-of-low-level-laser-therapy-on-tissue-repair-after-dental-extraction-in-rats-administered-zoledronic-acid-and-dexamethasone
#17
João Batista Blessmann Weber, Renata Stifelman Camilotti, Juliana Jasper, Liliane Cristina Onofre Casagrande, Fábio Luiz Dal Moro Maito
No abstract text is available yet for this article.
May 1, 2017: Journal of Biomedical Optics
https://www.readbyqxmd.com/read/28500821/serum-carbonic-anhydrase-1-is-a-biomarker-for-diagnosis-of-human-schistosoma-mansoni-infection
#18
Manal Ibrahim Kardoush, Brian J Ward, Momar Ndao
AbstractSchistosoma mansoni is a major public health threat in many parts of the world. The current diagnostic tests for schistosomiasis are suboptimal, particularly early in infection, when the parasite burden is low and with reinfection after treatment. We sought to identify novel biomarkers of active infection by studying serum proteins in a mouse model of schistosomiasis followed by confirmation in chronically infected patients. Acute (6 weeks) and chronic (12 weeks) sera from S. mansoni-infected C57Bl/6 mice as well as sera from chronically infected patients were assessed using two proteomic platforms: surface-enhanced, laser desorption and ionization, time-of-flight mass spectrometry and Velos Orbitrap mass spectrometry...
April 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28499707/lower-laser-energy-levels-lead-to-better-visual-recovery-after-small-incision-lenticule-extraction-prospective-randomized-clinical-trial
#19
Yong Woo Ji, Minseo Kim, David Sung Yong Kang, Dan Reinstein, Timothy Archer, Jin Young Choi, Eung Kweon Kim, Hyung Keun Lee, Kyoung Yul Seo, Tae-Im Kim
PURPOSE: To determine the effect of lowering laser energy on clinical outcomes in small-incision lenticule extraction (SMILE). DESIGN: Prospective, randomized clinical trial. METHODS: 151 patients (151 eyes) with moderate myopia scheduled for SMILE were included: 58 eyes received SMILE with low energy (100, 105, and 110 nJ; L-SMILE group) and 93 with conventional energy (115 to 150 nJ; C-SMILE group). Patients received complete ophthalmic examinations preoperatively and over 3 months postoperatively...
May 9, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28497233/standardization-and-optimization-of-intraoperative-molecular-imaging-for-identifying-primary-pulmonary-adenocarcinomas
#20
Jarrod D Predina, Olugbenga Okusanya, Andrew D Newton, Philip Low, Sunil Singhal
PURPOSE: Intraoperative molecular imaging (IMI) is an emerging technology used to locate pulmonary adenocarcinomas and identify positive margins during surgery. Background noise and tissue autofluorescence have been major obstacles. The goal of this study is to optimize the image quality of folate receptor alpha (FRα) targeted IMI for pulmonary adenocarcinomas by modifying emission data. PROCEDURES: A total of 15 lung cancer patients were enrolled in a pilot study...
May 11, 2017: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
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