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https://www.readbyqxmd.com/read/28099448/the-effects-of-low-power-laser-irradiation-on-inflammation-and-apoptosis-in-submandibular-glands-of-diabetes-induced-rats
#1
Cíntia Yuki Fukuoka, Alyne Simões, Toshikazu Uchiyama, Victor Elias Arana-Chavez, Yoshimitsu Abiko, Noboru Kuboyama, Ujjal K Bhawal
Diabetes can lead to dysfunction of the secretory capacity in salivary glands. Activation of the receptor for advanced glycation end products (RAGE) and its ligands has been suggested to participate in chronic disorders such as diabetes and its complications. In this study, the expression of RAGE, high mobility group box 1 (HMGB1) and advanced glycation end products (AGE), as well as the effects of low-power laser irradiation (LPLI) in salivary glands of diabetic rats were evaluated, and the mechanisms involved were characterized...
2017: PloS One
https://www.readbyqxmd.com/read/28093356/laser-and-photochemotherapy-for-the-treatment-of-oral-mucositis-in-young-patients-randomized-clinical-trial
#2
João Batista Medeiros Filho, Etevaldo Matos Maia Filho, Meire Coelho Ferreira
BACKGROUND: The aim of the present study was to evaluate the effect of low-level laser therapy (LLLT) combined with photochemotherapy (PCT) for the treatment of chemotherapy-induced oral mucositis in young patients. METHODS: A randomized, blind, clinical trial with a split-mouth design was conducted involving a sample of 15 cancer patients aged three to 16 years at the Aldenora Bello Hospital in the city of São Luís, Brazil. The treatments (PCT+LLLT and LLLT alone) were randomly determined for each side of the oral cavity...
January 13, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28092488/low-level-laser-therapy-in-enhancing-wound-healing-and-preserving-tissue-thickness-at-free-gingival-graft-donor-sites-a-randomized-controlled-clinical-study
#3
Gulbahar Ustaoglu, Esra Ercan, Mustafa Tunali
OBJECTIVE: The aim of this study was to determine the effects of low-level laser therapy (LLLT) on wound healing at free gingival graft (FGG) donor sites. MATERIALS AND METHODS: Forty patients requiring FGG were selected for this randomized, controlled, and double-blinded prospective clinical trial. The FGG donor sites were treated with LLLT and compared with an untreated control group. The Wound-Healing Index (WHI), tissue consistency, color match, and H2O2 bubbling test for the evaluation of complete wound epithelialization were recorded on the 3rd, 7th, 14th and 21st days...
January 12, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28088116/upconversion-color-tuning-in-ce-3-doped-liyf4-yb-3-ho-3-liyf4-nanoparticles-towards-ratiometric-fluorescence-detection-of-chromium-iii
#4
Shijiang Liu, Yangjie Li, Cheng Zhang, Liang Yang, Tingting Zhao, Ruilong Zhang, Changlong Jiang
Ratiometric fluorescence sensor exhibits advantages of sensitive response, high anti-interference ability and naked eye visualization owing to multiple independent emission peaks utilized for results analysis. To achieve such multi-emission probe, the traditional methods have involved simple mixing of two emitters or tedious synthesis processes of hybrid material. However, these probes often have problems of inconstant emission strength ratio, low light-stability, and complicated synthetic process, which limit their applications in practical field...
January 7, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28088107/gaas-laser-therapy-reestablishes-the-morphology-of-the-nmj-and-nachrs-after-injury-due-to-bupivacaine
#5
Cristiane Neves Alessi Pissulin, Paula Aiello Tomé de Souza Castro, Flávio Codina, Carina Guidi Pinto, Ivan Jose Vechetti-Junior, Selma Maria Michelin Matheus
BACKGROUND: Local anesthetics are used to relieve pre- and postoperative pain, acting on both sodium channels and nicotinic acetylcholine receptors (nAChR) at the neuromuscular junction (NMJ). Bupivacaine acts as a non-competitive antagonist and has limitations, such as myotoxicity, neurotoxicity, and inflammation. Low-level laser therapy (LLLT) has anti-inflammatory, regenerative, and analgesic effects. The aim of the present study was to evaluate the effects of a gallium arsenide laser (GaAs) on the morphology of the NMJ and nAChRs after application of bupivacaine in the sternomastoid muscle...
December 22, 2016: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28080917/results-of-the-megaverebrate-analgesia-survey-giraffe-and-hippopotamus
#6
Matthew Boothe, Jack Kottwitz, Roy Harmon, Scott B Citino, Jeffery R Zuba, Dawn M Boothe
Results of an online survey posted on the American Association of Zoo Veterinarians listserv examined the patterns of analgesic medication and pain management modalities used for captive giraffe and hippopotami. Compiled data included signalment, drugs administered, dosing regimens, subjective efficacy scores, ease of administration, and adverse events. Nineteen institutions exhibiting hippopotami ( Hippopotamus amphibious ) and pygmy hippopotami (Choeropsis liberiensis) and 45 exhibiting giraffe ( Giraffa camelopardalis spp...
December 2016: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28079117/high-field-transport-properties-of-a-p-doped-bafe2as2-film-on-technical-substrate
#7
Kazumasa Iida, Hikaru Sato, Chiara Tarantini, Jens Hänisch, Jan Jaroszynski, Hidenori Hiramatsu, Bernhard Holzapfel, Hideo Hosono
High temperature (high-Tc) superconductors like cuprates have superior critical current properties in magnetic fields over other superconductors. However, superconducting wires for high-field-magnet applications are still dominated by low-Tc Nb3Sn due probably to cost and processing issues. The recent discovery of a second class of high-Tc materials, Fe-based superconductors, may provide another option for high-field-magnet wires. In particular, AEFe2As2 (AE: Alkali earth elements, AE-122) is one of the best candidates for high-field-magnet applications because of its high upper critical field, Hc2, moderate Hc2 anisotropy, and intermediate Tc...
January 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28078845/effect-of-low-energy-light-irradiation-by-light-emitting-diode-on-u937-cells
#8
G Spoto, V De Iuliis, M Petrini, V Flati, J Di Gregorio, D Vitale, M Caruso, V Dadorante, M Ciarmoli, I Robuffo, S Martinotti, E Toniato
Photobiomodulation (PBM) can induce a set of different biological modulators either in vitro or in vivo. Experimental evidence has highlighted the role of light effects on the mechanisms related to inflammation, apoptosis and autophagy. The goal of this project was the evaluation of PBM on U937, an established cell line of histiocytic lymphoma origin. Several aspects of modulation of proinflammatory pathways were analyzed and autophagic and proapoptotic mechanisms related to low laser light exposure of cells were studied...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28076498/the-efficacy-of-low-level-940-nm-laser-therapy-with-different-energy-intensities-on-bone-healing
#9
Kerem Turgut Atasoy, Yavuz Tolga Korkmaz, Ersan Odaci, Hatice Hanci
The aim of this study was to evaluate the efficacy of low-level 940 nm laser therapy with energy intensities of 5, 10 and 20 J/cm2 on bone healing in an animal model. A total of 48 female adult Wistar rats underwent surgery to create bone defects in the right tibias. Low-level laser therapy (LLLT) was applied immediately after surgery and on post-operative days 2, 4, 6, 8, 10 and 12 in three study groups with energy intensities of 5 J/cm2, 10 J/cm2 and 20 J/cm2 using a 940 nm Gallium-Aluminium-Arsenide (Ga-Al-As) laser, while one control group underwent only the tibia defect surgery...
January 5, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/28075022/the-mechanistic-basis-for-photobiomodulation-therapy-of-neuropathic-pain-by-near-infrared-laser-light
#10
Vanessa Milanesi Holanda, Maria Cristina Chavantes, Xingjia Wu, Juanita J Anders
BACKGROUND AND OBJECTIVE: Various irradiances have been reported to be beneficial for the treatment of neuropathic pain with near infrared light. However, the mechanistic basis for the beneficial outcomes may vary based on the level of irradiance or fluence rate used. Using in vivo and in vitro experimental models, this study determined the mechanistic basis of photobiomodulation therapy (PBMT) for the treatment of neuropathic pain using a high irradiance. STUDY DESIGN/MATERIALS AND METHODS: In vitro experiments: Cultured, rat DRG were randomly assigned to control or laser treatment (LT) groups with different irradiation times (2, 5, 30, 60, or 120 seconds)...
January 11, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28074796/low-intensity-laser-660-nm-has-analgesic-effects-on-sternotomy-of-patients-who-underwent-coronary-artery-bypass-grafts
#11
Gilderlene Alves Fernandes, Raimundo de Barros Araújo Júnior, Andréa Conceição Gomes Lima, Isabel Clarisse Albuquerque Gonzaga, Rauirys Alencar de Oliveira, Renata Amadei Nicolau
BACKGROUND: The aim of this study was to evaluate the efficacy of low-level laser therapy for reducing the acute pain of sternotomy in patients who underwent a coronary artery bypass graft (CABG). METHODS: This study was conducted with ninety volunteers who electively submitted to CABG. The volunteers were randomly allocated into three groups of equal size (n = 30): control, placebo, and laser (λ of 660 nm and spatial average energy fluency of 1.06 J/cm 2 ). Pain when coughing was assessed by a visual analog scale (VAS) and McGill Pain Questionnaire, according to sensory, affective, evaluative, and miscellaneous domains...
January 2017: Annals of Cardiac Anaesthesia
https://www.readbyqxmd.com/read/28074305/clinical-effectiveness-of-low-level-laser-treatment-on-peripheral-somatosensory-neuropathy
#12
REVIEW
Alireza Fallah, Alireza Mirzaei, Norbert Gutknecht, Amir Saberi Demneh
Peripheral sensory neuropathy treatment is one of the common treatment problems and causes morbidity and mortality in people suffering from that. Although treatment depends on the underlying cause of the condition, nevertheless, in some cases, there is no cure for it, and it requires palliative and symptomatic treatment. In laboratory studies, low-level laser has been effective in the nerves protection and restoration. The aim of this article is to investigate the clinical efficacy of low-level laser on improvement of the peripheral somatosensory neuropathy...
January 10, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28070154/proposed-mechanisms-of-photobiomodulation-or-low-level-light-therapy
#13
Lucas Freitas de Freitas, Michael R Hamblin
Photobiomodulation (PBM) also known as low-level laser (or light) therapy (LLLT), has been known for almost 50 years but still has not gained widespread acceptance, largely due to uncertainty about the molecular, cellular, and tissular mechanisms of action. However, in recent years, much knowledge has been gained in this area, which will be summarized in this review. One of the most important chromophores is cytochrome c oxidase (unit IV in the mitochondrial respiratory chain), which contains both heme and copper centers and absorbs light into the near-infra-red region...
May 2016: IEEE Journal of Selected Topics in Quantum Electronics
https://www.readbyqxmd.com/read/28067288/10-fs-level-synchronization-of-photocathode-laser-with-rf-oscillator-for-ultrafast-electron-and-x-ray-sources
#14
Heewon Yang, Byungheon Han, Junho Shin, Dong Hou, Hayun Chung, In Hyung Baek, Young Uk Jeong, Jungwon Kim
Ultrafast electron-based coherent radiation sources, such as free-electron lasers (FELs), ultrafast electron diffraction (UED) and Thomson-scattering sources, are becoming more important sources in today's ultrafast science. Photocathode laser is an indispensable common subsystem in these sources that generates ultrafast electron pulses. To fully exploit the potentials of these sources, especially for pump-probe experiments, it is important to achieve high-precision synchronization between the photocathode laser and radio-frequency (RF) sources that manipulate electron pulses...
January 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28063775/assessment-of-head-displacement-and-disassembly-force-with-increasing-assembly-load-at-the-head-trunnion-junction-of-a-total-hip-arthroplasty-prosthesis
#15
Darryl N Ramoutar, Emilie A Crosnier, Faiz Shivji, Anthony W Miles, Harinderjit S Gill
BACKGROUND: Most femoral components used now for total hip arthroplasty are modular, requiring a strong connection at assembly. The aim of this study was to assess the effect of assembly force on the strength of head-trunnion interface and to measure the initial displacement of the head on the trunnion with different assembly forces. METHODS: Three assembly load levels were assessed (A: 2 kN, B: 4 kN, C: 6 kN) with 4 implants in each group. The stems were mounted in a custom rig and the respective assembly loads were applied to the head at a constant rate of 0...
December 14, 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28063018/analysis-of-the-variation-in-low-level-laser-energy-density-on-the-crushed-sciatic-nerves-of-rats-a-morphological-quantitative-and-morphometric-study
#16
Eduardo Keiske Mastuda Ziago, Valéria Paula Sassoli Fazan, Mamie Mizusaki Iyomasa, Luiz Gustavo Sousa, Paula Yumi Yamauchi, Eunice Aparecida da Silva, Eduardo Borie, Ramón Fuentes, Fernando José Dias
The objective of this study was to evaluate three energy densities of low-level laser therapy (LLLT, GaAlAs, 780 nm, 40 mW, 0.04 cm(2)) for the treatment of lesions to peripheral nerves using the sciatic nerve of rats injured via crushing model (15 kgf, 5.2 MPa). Thirty Wistar rats (♂, 200-250 g) were divided into five groups (n = 6): C-control, not injured, and irradiated; L0-injured nerve without irradiation; L4-injured nerve irradiated with LLLT 4 J/cm(2) (0.16 J); L10-injured nerve irradiated with LLLT 10 J/cm(2) (0...
January 7, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28062948/low-levels-of-prohibitin-in-substantia-nigra-makes-dopaminergic-neurons-vulnerable-in-parkinson-s-disease
#17
Debashis Dutta, Nilufar Ali, Emili Banerjee, Raghavendra Singh, Amit Naskar, Ramesh Kumar Paidi, Kochupurackal P Mohanakumar
Since substantia nigra (SN) and ventral tegmental area (VTA) dopaminergic neurons are, respectively, susceptible or largely unaffected in Parkinson's disease (PD), we searched for protein(s) that regulates this differential sensitivity. Differentially, expressed proteins in SN and VTA were investigated employing two-directional gel electrophoresis- matrix-assisted laser desorption ionization time of flight (MALDI-TOF-TOF) analyses. Prohibitin, which is involved in mitochondrial integrity, was validated using immunoblot, qRT-PCR, and immunohistochemistry in normal mice as well as 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-model, PD postmortem human brains, and PD cybrids...
January 6, 2017: Molecular Neurobiology
https://www.readbyqxmd.com/read/28061966/new-treatments-for-hair-loss
#18
S Vañó-Galván, F Camacho
The treatment of hair loss is an important part of clinical dermatology given the prevalence of the problem and great impact on patients' quality of life. Many new treatments have been introduced in recent years. This review summarizes the main ones in 4 groups: a) For androgenetic alopecia, we discuss new excipients for oral minoxidil, dutasteride, and finasteride as well as new forms of topical application; prostaglandin agonists and antagonists; low-level laser therapy; and regenerative medicine with Wnt signaling activators and stem cell therapy...
January 3, 2017: Actas Dermo-sifiliográficas
https://www.readbyqxmd.com/read/28060875/correlations-of-neck-shoulder-perfusion-characteristics-and-pain-symptoms-of-the-female-office-workers-with-sedentary-lifestyle
#19
Jian-Guo Bau, Taipau Chia, Shan-Hua Wei, Yung-Hui Li, Fun-Chie Kuo
AIM: Modern office workers are often impacted by chronic neck/shoulder pain. Most of the previous studies which investigated the relationship of the occupational factors and musculoskeletal symptoms had adopted questionnaire survey. In this study the microcirculatory characteristics and perceived symptoms in neck/shoulder region were compared among office workers with sedentary lifestyle. METHODS: Thirty-seven female office workers were recruited in this study. Microcirculatory flow in neck/shoulder region characterized by the mean blood flow (MMBF value), pulsatile blood flow (PMBF value), and the PMBF/MMBF ratio (perfusion pulsatility, PP) were investigated using Laser Doppler Flowmetry (LDF)...
2017: PloS One
https://www.readbyqxmd.com/read/28056485/evidence-of-invasive-and-non-invasive-treatment-modalities-for-hypertrophic-scars-a-systematic-review
#20
Mona Kafka, Vanessa Collins, Lars-Peter Kamolz, Thomas Rappl, Ludwik K Branski, Paul Wurzer
Currently, there are various therapeutic approaches to reduce hypertrophic scarring, however, there is no standard evidence-based treatment protocol. Hence, we performed a systematic review to obtain a summary of the latest clinical trials to evaluate evidence for the treatment of hypertrophic scars. The review protocol was registered and approved by PROSPERO (CRD42015027040). PubMed and Web of Science were searched using predefined MeSH-Terms to identify studies published within the last 10 years regarding treatment for hypertrophic scars...
January 5, 2017: Wound Repair and Regeneration
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