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https://www.readbyqxmd.com/read/28328705/novel-approach-to-treating-androgenetic-alopecia-in-females-with-photobiomodulation-low-level-laser-therapy
#1
Shelly Friedman, Patricia Schnoor
BACKGROUND: Photobiomodulation, also referred to as low-level laser therapy (LLLT), has been studied and used for (among other diseases) the promotion of hair regrowth. OBJECTIVE/MATERIALS AND METHODS/RESULTS: A clinical study was developed to define the physiologic effects that occur when the human hair follicle and surrounding tissue structures are exposed to laser light using a novel device that is fitted with an array of laser diode sources operating at 650 nm and placed inside a sports cap to promote discretion while in use...
March 21, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28328200/fluorescence-resonance-energy-transfer-based-dna-tetrahedron-nano-tweezer-for-highly-reliable-detection-of-tumor-related-mrna-in-living-cells
#2
Lei He, Dan-Qing Lu, Hao Liang, Sitao Xie, Can Luo, Miaomiao Hu, Liujun Xu, Xiaobing Zhang, Weihong Tan
Accurate detection and imaging of tumor-related mRNA in living cells hold great promise for early cancer detection. However, currently, most probes designed to image intracellular mRNA confront intrinsic interferences arising from complex biological matrices and resulting in inevitable false-positive signals. To circumvent this problem, a new class of intracellular DNA nanoprobe, termed DNA tetrahedron nano-tweezer (DTNT), was developed to reliably image tumor-related mRNA in living cells based on the FRET (fluorescence resonance energy transfer) "off" to "on" signal readout mode...
March 22, 2017: ACS Nano
https://www.readbyqxmd.com/read/28324452/a-review-of-ranibizumab-for-the-treatment-of-diabetic-retinopathy
#3
REVIEW
Michael W Stewart
INTRODUCTION: Laser photocoagulation has been the standard treatment for diabetic macular edema (DME) and proliferative diabetic retinopathy (PDR) for several decades. The discovery of vascular endothelial growth factor (VEGF) and the subsequent determination of its critical role in the development DME and PDR has led to the development of VEGF inhibitory drugs. Ranibizumab was the first anti-VEGF drug approved for the treatment of both DME and diabetic retinopathy in eyes with DME. METHODS: Medline searches with the keywords "ranibizumab," "diabetic macular edema," and "proliferative diabetic retinopathy" were performed to identify pertinent pre-clinical studies and clinical trials...
March 21, 2017: Ophthalmology and Therapy
https://www.readbyqxmd.com/read/28323482/constraints-on-the-early-terrestrial-surface-uv-environment-relevant-to-prebiotic-chemistry
#4
Sukrit Ranjan, Dimitar D Sasselov
The UV environment is a key boundary condition to abiogenesis. However, considerable uncertainty exists as to planetary conditions and hence surface UV at abiogenesis. Here, we present two-stream multilayer clear-sky calculations of the UV surface radiance on Earth at 3.9 Ga to constrain the UV surface fluence as a function of albedo, solar zenith angle (SZA), and atmospheric composition. Variation in albedo and latitude (through SZA) can affect maximum photoreaction rates by a factor of >10.4; for the same atmosphere, photoreactions can proceed an order of magnitude faster at the equator of a snowball Earth than at the poles of a warmer world...
March 2017: Astrobiology
https://www.readbyqxmd.com/read/28321128/continuous-wave-lasing-in-colloidal-quantum-dot-solids-enabled-by-facet-selective-epitaxy
#5
Fengjia Fan, Oleksandr Voznyy, Randy P Sabatini, Kristopher T Bicanic, Michael M Adachi, James R McBride, Kemar R Reid, Young-Shin Park, Xiyan Li, Ankit Jain, Rafael Quintero-Bermudez, Mayuran Saravanapavanantham, Min Liu, Marek Korkusinski, Pawel Hawrylak, Victor I Klimov, Sandra J Rosenthal, Sjoerd Hoogland, Edward H Sargent
Colloidal quantum dots (CQDs) feature a low degeneracy of electronic states at the band edges compared with the corresponding bulk material, as well as a narrow emission linewidth. Unfortunately for potential laser applications, this degeneracy is incompletely lifted in the valence band, spreading the hole population among several states at room temperature. This leads to increased optical gain thresholds, demanding high photoexcitation levels to achieve population inversion (more electrons in excited states than in ground states-the condition for optical gain)...
March 20, 2017: Nature
https://www.readbyqxmd.com/read/28318581/characterization-of-the-chemical-structures-and-physical-properties-of-exopolysaccharides-produced-by-various-streptococcus-thermophilus-strains
#6
U Pachekrepapol, J A Lucey, Y Gong, R Naran, P Azadi
Exopolysaccharides (EPS) produced by some lactic acid bacteria are often used by the dairy industry to improve the rheological and physical properties of yogurt, but the relationship between their structure and functional effect is still unclear. The EPS from different species, or different strains from the same species, may differ in terms of molar mass, repeating unit structure, and EPS yield during fermentation of milk. This study aimed to characterize the detailed properties of EPS produced from 7 strains of Streptococcus thermophilus, which is one of the key cultures used for yogurt manufacture...
March 16, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28318232/histology-compatible-maldi-mass-spectrometry-based-imaging-of-neuronal-lipids-for-subsequent-immunofluorescent-staining
#7
Ibrahim Kaya, Wojciech Michno, Dimitri Brinet, Yasmine Iacone, Giulia Zanni, Kaj Blennow, Henrik Zetterberg, Jörg Hanrieder
Matrix assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) enables acquisition of spatial distribution maps for molecular species in situ. This can provide comprehensive insights on the pathophysiology of different diseases. However, current sample preparation and MALDI-IMS acquisition methods have limitations in preserving molecular and histological tissue morphology, resulting in interfered correspondence of MALDI-IMS data with subsequently acquired immunofluorescent staining results...
March 20, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28306248/temperature-sensing-using-thermal-population-of-low-lying-energy-levels-with-sm0-01gd0-99-vo4
#8
Jiajia Cai, Lu Zhao, Fangfang Hu, Xiantao Wei, Yonghu Chen, Min Yin, Chang-Kui Duan
A temperature sensing scheme is proposed that is based on the dramatic temperature dependence of the photoluminescence when Sm(3+) dopants are excited from thermally populated (6)H7/2,9/2 levels, rather than the ground level (6)H5/2, to the (4)G5/2 luminescent level. The scheme has the advantage of eliminating laser heating and background Stokes-type scattering noise. Experimental realization was carried out on a (Sm0.01Gd0.99)VO4 sample by detecting the intensities at 550-580 nm using excitation wavelengths of 601...
March 17, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28301678/effectiveness-of-adjunctive-interventions-for-accelerating-orthodontic-tooth-movement-a-systematic-review-of-systematic-reviews
#9
REVIEW
Jianru Yi, Jiani Xiao, Hanshi Li, Yu Li, Xiaobing Li, Zhihe Zhao
This study was aimed to summarize published systematic reviews that assess the effects of adjunctive interventions on the acceleration of orthodontic tooth movement (OTM). Electronic and manual searches were performed up to Aug 2016. Systematic reviews investigating the impact of adjunctive techniques on the promotion of OTM were included. The methodological quality of the included reviews was evaluated using the AMSTAR scale. The quality of evidence for each intervention was assessed using GRADE. The Jadad decision algorithm was used to select a study to provide body evidence from discordant reviews on the same intervention...
March 16, 2017: Journal of Oral Rehabilitation
https://www.readbyqxmd.com/read/28297096/accelerated-orthodontic-treatment-what-s-the-evidence
#10
P Miles
The demand and accessibility of orthodontic care has increased but has also been accompanied by patient requests for shorter treatment times. Longer orthodontic treatment increases the risk of decalcification, gingival recession, and root resorption and so shorter treatment times have multiple advantages as well as appealing to patient's desires. Numerous techniques and materials have been suggested to reduce treatment times but, in most cases, are based upon selected case reports with no prospective clinical trials to validate claims...
March 2017: Australian Dental Journal
https://www.readbyqxmd.com/read/28296509/tp53-and-atm-mrna-expression-in-skin-and-skeletal-muscle-after-low-level-laser-exposure
#11
Luciana Guedes de Almeida, Luiz Philippe da Silva Sergio, Flavia de Paoli, Andre Luiz Mencalha, Adenilson de Souza da Fonseca
Low-level lasers are widespread in regenerative medicine, but the molecular mechanisms involved in their biological effects are not fully understood, particularly those on DNA stability. Therefore, this study aimed to investigate mRNA expression of genes related to DNA genomic stability in skin and skeletal muscle tissue from Wistar rats exposed to low-level red and infrared lasers. For this, TP53 (Tumor Protein 53) and ATM (Ataxia Telangiectasia Mutated gene) mRNA expressions were evaluated by real-time quantitative PCR (RT-qPCR) technique 24 hours after low-level red and infrared laser exposure...
February 16, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28295090/secure-key-distribution-based-on-chaos-synchronization-of-vcsels-subject-to-symmetric-random-polarization-optical-injection
#12
Ning Jiang, Chenpeng Xue, Ding Liu, Yunxin Lv, Kun Qiu
We propose and numerically demonstrate a secure key distribution scheme based on the dynamic chaos synchronization of two external cavity vertical-cavity surface-emitting lasers (VCSELs) subject to symmetric random-polarization injections. By exchanging the random parameters that control the polarization angles of the driving injection, Alice and Bob can identify the time slots in which high-quality private chaos synchronization is achieved and independently generate a shared key from the synchronized polarization difference signals of their local VCSELs...
March 15, 2017: Optics Letters
https://www.readbyqxmd.com/read/28294933/differences-in-sheep-and-goats-milk-microbiological-profile-between-conventional-and-organic-farming-systems-in-greece
#13
Eleni Malissiova, Theofilos Papadopoulos, Aikaterini Kyriazi, Maria Mparda, Christina Sakorafa, Antonios Katsioulis, Anna Katsiaflaka, Maria Kyritsi, Antonios Zdragas, Christos Hadjichristodoulou
The aim of this study was to examine differences in the microbiological profile and antimicrobial resistance of bacteria isolated from milk from organic and conventional sheep and goat farms. Twenty-five organic and 25 conventional sheep and goat farms in the region of Thessaly, Greece participated in this study. A standardised detailed questionnaire was used to describe farming practices. A total of 50 samples were collected and analysed for total viable count (TVC), total coliform count (TCC) and somatic cell count (SCC), while Staphylococcus aureus and Escherichia coli were isolated using standard methods...
March 15, 2017: Journal of Dairy Research
https://www.readbyqxmd.com/read/28294706/histopathological-microbiological-and-radiographic-analysis-of-antimicrobial-photodynamic-therapy-for-the-treatment-of-teeth-with-apical-periodontitis-a-study-in-rats-molars
#14
Alessandra Cesar Trindade, José Antônio Poli de Figueiredo, Sílvia Dias de Oliveira, Valdir Cristóvão Barth Junior, Stephanie Wagner Gallo, Carina Follmann, Carlos Frederico Brilhante Wolle, Liviu Steier, Renata Dornelles Morgental, João Batista Blessmann Weber
OBJECTIVE: The aim of this study was to evaluate in vivo, by histological and radiographic analysis, the response of apical tissues of rats' teeth with experimentally induced apical periodontitis, after one- and two-session endodontic treatment with and without photodynamic therapy (PDT). A microbiological analysis was also performed to verify bacterial reduction after each treatment. BACKGROUND DATA: Studies carried out in recent years highlighted the antibacterial potential of PDT when associated with conventional endodontic therapy in vitro...
March 9, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28294697/efficacy-of-low-level-laser-therapy-in-subjective-tinnitus-patients-with-temporomandibular-disorders
#15
Nermin Demirkol, Aslihan Usumez, Mehmet Demirkol, Fatih Sari, Cihan Akcaboy
OBJECTIVE AND BACKGROUND: Tinnitus is an apparent sound, perceived in the ear with no stimulus. It has been described as a sound originating from the brain. It affects 17% of the general population. Etiological factors for tinnitus include temporomandibular joint disorders (TMJ, TMD) and Costen's syndrome. The aim of treatment is to eliminate the tinnitus or at least decrease its apparent volume. MATERIALS AND METHODS: In total, 46 patients referred to our department with bilateral subjective tinnitus with TMDs were selected for this study...
March 14, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28294694/the-effects-of-transcutaneous-and-intraoral-low-level-laser-therapy-after-extraction-of-lower-third-molars-a-randomized-single-blind-placebo-controlled-dual-center-study
#16
Sevil Altundag Kahraman, Sedat Cetiner, Robert A Strauss
OBJECTIVE AND BACKGROUND: The surgical removal of impacted third molars is one of the most common procedures performed by oral and maxillofacial surgeons. The purpose of this study is to determine whether either transcutaneous or intraoral low-level laser therapy (LLLT) reduces postoperative pain and assists in the healing of mandibular third molar extraction. MATERIALS AND METHODS: This randomized, placebo controlled, single-blind, split-mouth design study was conducted on 60 patients with full bony impacted similar position mandibular third molars bilaterally...
March 14, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28292696/influence-of-low-level-laser-therapy-on-the-healing-of-human-bone-maxillofacial-defects-a-systematic-review
#17
Carolina Dos Santos Santinoni, Hiskell Francine Fernandes Oliveira, Victor Eduardo de Souza Batista, Cleidiel Aparecido Araujo Lemos, Fellippo Ramos Verri
PURPOSE: This systematic review evaluates the effectiveness of low-level laser therapy (LLLT) to enhance maxillofacial area bone repair. METHODS: A comprehensive search of studies published up to February 2017 and listed in PubMed/MEDLINE, Scopus, and Cochrane Library databases was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. RESULTS: The 15 selected studies evaluated a total of 374 patients (mean age, 28...
March 7, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28289894/the-effect-of-low-level-laser-therapy-on-tooth-movement-during-canine-distalization
#18
Sevin Erol Üretürk, Müyesser Saraç, Sönmez Fıratlı, Şule Batu Can, Yegane Güven, Erhan Fıratlı
The aim of the study is to determine the effects of low level laser therapy on tooth movement during canine distalization by evaluating IL-1β, TGF-β1 levels in gingival crevicular fluid. Maxillary first premolars of the 15 Angle Class II division I patients (12-19 years old) were extracted. Right maxillary canines were distalized by standard protocol as control group whereas the left maxillary canines distalized by laser application. A gallium-aluminum-arsenide diode laser with an output power of 20 mW was applied as five doses from the buccal and the palatal side on the day 0, and the 3rd, 7th, 14th, 21th 30th, 33st, 37th, 60th, 63th, and 67th days...
March 14, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28285410/epithelial-cell-enhanced-metabolism-by-low-level-laser-therapy-and-epidermal-growth-factor
#19
Fernanda Gonçalves Basso, Taisa Nogueira Pansani, Lais Medeiros Cardoso, Mariana Citta, Diana Gabriela Soares, Débora Salles Scheffel, Josimeri Hebling, Carlos Alberto de Souza Costa
Reepithelialization and wound closure are the desired outcome for several ulcerative conditions. Such resolution reduces the possibility of wound contamination and maintenance of the injury and improves the reestablishment of tissue morphology and functions. Investigators are seeking adjuvant therapies that can accelerate wound healing and are developing new strategies for clinical applications. This study compared the effects of epidermal growth factor (EGF) application and low-level laser therapy (LLLT) on cultured epithelial cells...
March 11, 2017: Lasers in Medical Science
https://www.readbyqxmd.com/read/28282803/blood-storage-alters-mechanical-stress-responses-of-erythrocytes
#20
Elif Ugurel, Zeynep Kucuksumer, Buse Eglenen, Ozlem Yalcin
BACKGROUND: Erythrocytes undergo irreversible morphological and biochemical changes during storage. Reduced levels of deformability have been reported for stored erythrocytes. Erythrocyte deformability is essential for healthy microcirculation. OBJECTIVE: The aim of this study is to evaluate shear stress (SS) induced improvements of erythrocyte deformability in stored blood. METHODS: Deformability changes were evaluated by applying physiological levels of SS (5 and 10 Pa) in metabolically depleted blood for 48 hours and stored blood for 35 days with citrate phosphate dextrose adenine-1 (CPDA-1)...
March 4, 2017: Clinical Hemorheology and Microcirculation
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