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https://www.readbyqxmd.com/read/28636327/maldi-ms-guided-liquid-microjunction-extraction-for-ce-esi-ms-analysis-of-single-pancreatic-islet-cells
#1
Troy J Comi, Monika A Makurath, Marina C Philip, Stanislav S Rubakhin, Jonathan V Sweedler
The ability to characterize chemical heterogeneity in biological structures is essential to understanding cellular level function in both healthy and diseased states, but these variations remain difficult to assess using a single analytical technique. While mass spectrometry (MS) provides sufficient sensitivity to measure many analytes from volume-limited samples, each type of mass spectrometric analysis uncovers only a portion of the complete chemical profile of a single cell. Matrix-assisted laser desorp-tion/ionization (MALDI) MS and capillary electrophoresis electrospray ionization (CE-ESI)-MS are complementary analytical platforms frequently utilized for single cell analysis...
June 21, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28633773/magnetic-resonance-imaging-and-clinical-outcomes-of-laser-therapy-ultrasound-therapy-and-extracorporeal-shock-wave-therapy-for-treatment-of-plantar-fasciitis-a-randomized-controlled-trial
#2
Aslihan Ulusoy, Lale Cerrahoglu, Sebnem Orguc
We determined and compared the effectiveness of low-level laser therapy (LLLT), therapeutic ultrasound (US) therapy, and extracorporeal shock wave therapy (ESWT) using magnetic resonance imaging (MRI). We performed a randomized, prospective, comparative clinical study. A total of 60 patients with a diagnosis of chronic plantar fasciitis were divided randomly into 3 treatment groups: group 1 underwent 15 sessions of LLLT (8 J/cm(2); 830 nm); group 2 underwent 15 sessions of continuous US (1 mHz; 2 W/cm(2)); and group 3 underwent 3 sessions of ESWT (2000 shocks)...
July 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28629992/do-patients-with-carpal-tunnel-syndrome-benefit-from-low-level-laser-therapy-a-systematic-review-of-randomized-controlled-trials
#3
REVIEW
Thierry P C Franke, Bart W Koes, Sven J G Geelen, Bionka M A Huisstede
OBJECTIVE: To systematically review the literature on the effectiveness of low-level laser therapy for patients with carpal tunnel syndrome. DATA SOURCES: The Cochrane Library, PubMed, EMBASE, CINAHL, and PEDro were searched for relevant systematic reviews and randomized controlled trials (RCTs) up to April 8 2016. STUDY SELECTION: Two reviewers independently applied the inclusion criteria to select potential studies. DATA EXTRACTION: Two reviewers independently extracted the data and assessed the methodological quality...
June 16, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28628423/current-considerations-for-low-level-laser-therapy-photobiomodulation-therapy-in-the-management-of-side-effects-of-chemoradiation-therapy-for-cancer
#4
Kenji Yoshida
No abstract text is available yet for this article.
June 19, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28622041/the-effects-of-low-level-laser-therapy-on-the-healing-of-bone-defects-in-streptozotocin-induced-diabetic-rats-a-histological-and-morphometric-evaluation
#5
Senem Yildirimturk, Yigit Sirin, Merva Soluk Tekkesin, Gokhan Gurler, Deniz Firat
BACKGROUND: The aim of the present study was to evaluate the effects of LLLT on the healing of bone defects in rats with streptozotocin (STZ) induced DM. METHODS: 28 male Sprague-Dawley rats were used in this study. 14 animals received a single dose of STZ intraperitoneally (65 mg/kg) to induce Type I DM, whereas others were injected only with sterile saline solution. Four weeks later, standard bone defects were created in the tibiae of rats. Surgical wounds in one group from each of the diabetic and non-diabetic animals were irradiated with diode laser for every other day for 4 weeks and they were described as DM+LLLT and CONT+LLLT groups, respectively...
June 16, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28621568/presenting-a-method-to-improve-bone-quality-through-stimulation-of-osteoporotic-mesenchymal-stem-cells-by-low-level-laser-therapy
#6
Mohammad Bayat, Ali Jalalifirouzkouhi
OBJECTIVE: This review aims to present a method to improve bone quality through stimulation of osteoporotic mesenchymal stem cells (MSCs) by low-level laser therapy (LLLT). BACKGROUND: Osteoporosis (OP) is characterized by decreased bone mass and bone strength, which results in an increased incidence of bone fractures. These fractures often lead to additional disability and mortality. Osteoporotic MSCs have reduced osteogenic differentiation when cultured in their standard differentiation media...
June 15, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28621287/ibuprofen-and-low-level-laser-therapy-for-pain-control-during-fixed-orthodontic-therapy-a-systematic-review-of-randomized-controlled-trials-and-meta-analysis
#7
Faezeh Eslamipour, Saeed R Motamedian, Fahimeh Bagheri
INTRODUCTION: To systematically review high-quality randomized controlled trials (RCTs) and meta-analysis on the effectiveness of use of ibuprofen and low-level laser therapy (LLLT) for pain control during fixed orthodontic appliance therapy. MATERIALS AND METHODS: A web-based systematic search of PubMed and Medline database using relevant keywords was performed in August 2016 limited to the English language studies. Based on inclusion and exclusion criteria, RCTs utilizing blind approach were selected...
June 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28615939/effect-of-carbon-ion-implantation-on-the-tribology-of-metal-on-metal-bearings-for-artificial-joints
#8
Hironobu Koseki, Masato Tomita, Akihiko Yonekura, Takashi Higuchi, Sinya Sunagawa, Koumei Baba, Makoto Osaki
Metal-on-metal (MoM) bearings have become popular due to a major advantage over metal-on-polymer bearings for total hip arthroplasty in that the larger femoral head and hydrodynamic lubrication of the former reduce the rate of wear. However, concerns remain regarding adverse reactions to metal debris including metallosis caused by metal wear generated at the taper-head interface and another modular junction. Our group has hypothesized that carbon ion implantation (CII) may improve metal wear properties. The purpose of this study was to investigate the wear properties and friction coefficients of CII surfaces with an aim to ultimately apply these surfaces to MoM bearings in artificial joints...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28615654/6-2-ghz-modulated-terahertz-light-detection-using-fast-terahertz-quantum-well-photodetectors
#9
Hua Li, Wen-Jian Wan, Zhi-Yong Tan, Zhang-Long Fu, Hai-Xia Wang, Tao Zhou, Zi-Ping Li, Chang Wang, Xu-Guang Guo, Jun-Cheng Cao
The fast detection of terahertz radiation is of great importance for various applications such as fast imaging, high speed communications, and spectroscopy. Most commercial products capable of sensitively responding the terahertz radiation are thermal detectors, i.e., pyroelectric sensors and bolometers. This class of terahertz detectors is normally characterized by low modulation frequency (dozens or hundreds of Hz). Here we demonstrate the first fast semiconductor-based terahertz quantum well photodetectors by carefully designing the device structure and microwave transmission line for high frequency signal extraction...
June 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28611487/athermal-synchronization-of-laser-source-with-wdm-filter-in-a-silicon-photonics-platform
#10
Nanxi Li, Zhan Su, Purnawirman, E Salih Magden, Christopher V Poulton, Alfonso Ruocco, Neetesh Singh, Matthew J Byrd, Jonathan D B Bradley, Gerald Leake, Michael R Watts
In an optical interconnect circuit, microring resonators (MRRs) are commonly used in wavelength division multiplexing systems. To make the MRR and laser synchronized, the resonance wavelength of the MRR needs to be thermally controlled, and the power consumption becomes significant with a high-channel count. Here, we demonstrate an athermally synchronized rare-earth-doped laser and MRR. The laser comprises a Si3N4 based cavity covered with erbium-doped Al2O3 to provide gain. The low thermo-optic coefficient of Al2O3 and Si3N4 and the comparable thermal shift of the effective index in the laser and microring cross-sections enable lasing and resonance wavelength synchronization over a wide range of temperatures...
May 22, 2017: Applied Physics Letters
https://www.readbyqxmd.com/read/28608835/highly-sensitive-magnetic-sers-dual-function-silica-nanoprobes-for-effective-on-site-organic-chemical-detection
#11
Cheolhwan Jeong, Hyung-Mo Kim, So Yeon Park, Myeong Geun Cha, Sung-Jun Park, San Kyeong, Xuan-Hung Pham, Eunil Hahm, Yuna Ha, Dae Hong Jeong, Bong-Hyun Jun, Yoon-Sik Lee
We report magnetic silver nanoshells (M-AgNSs) that have both magnetic and SERS properties for SERS-based detection. The M-AgNSs are composed of hundreds of Fe₃O₄ nanoparticles for rapid accumulation and bumpy silver shell for sensitive SERS detection by near-infrared laser excitation. The intensity of the SERS signal from the M-AgNSs was strong enough to provide single particle-level detection. We obtained much stronger SERS signal intensity from the aggregated M-AgNSs than from the non-aggregated AgNSs...
June 13, 2017: Nanomaterials
https://www.readbyqxmd.com/read/28606650/low-level-laser-therapy-accelerates-the-extracellular-matrix-reorganization-of-inflamed-tendon
#12
Flávia Da Ré Guerra, Cristiano Pedrozo Vieira, Petrus Pires Marques, Letícia Prado Oliveira, Edson Rosa Pimentel
In tendon lesions, inflammation indicates the beginning of tissue repair and influences cell proliferation and the remodeling of the extracellular matrix (ECM). Low level laser (LLL) therapy has been an important method to induce tissue repair, and several studies have sought to better understand the therapeutic possibilities of this modality. This study analyzed the effect of LLL on the ECM of rat tendons during the early phase of the inflammatory process. Wistar rats received an intratendinous application of carrageenan adjacent to the osteotendinous region in the right paw...
June 3, 2017: Tissue & Cell
https://www.readbyqxmd.com/read/28603084/biosilicate-plga-osteogenic-effects-modulated-by-laser-therapy-in-vitro-and-in-vivo-studies
#13
K R Fernandes, A M P Magri, H W Kido, J R Parisi, L Assis, K P S Fernandes, R A Mesquita-Ferrari, V C Martins, A M Plepis, E D Zanotto, O Peitl, A C M Renno
The main purpose of the present work was to evaluate if low laser level therapy (LLLT) can improve the effects of Biosilicate®/PLGA (BS/PLGA) composites on cell viability and bone consolidation using a tibial defects of rats. The composites were characterized by scanning electron microscope (SEM) and reflection Fourier transform infrared spectrometer (FTIR). For the in vitro study, fibroblast and osteoblast cells were seeded in the extract of the composites irradiated or not with LLLT (Ga-Al-As, 808nm, 10J/cm(2)) to assess cell viability after 24, 48 and 72h...
June 3, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28602569/a-comparison-of-the-outcomes-of-four-minimally-invasive-treatment-methods-for-anterior-disc-displacement-of-the-temporomandibular-joint
#14
H Hosgor, B Bas, C Celenk
The purpose of this study was to compare the effectiveness of four non-surgical conservative treatment methods for temporomandibular disorders (TMD). The study group comprised 40 patients with unilateral TMD who fell into group II of the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD). Patients were divided into four groups according to the treatment method: splint therapy, arthrocentesis, medical therapy, and low-level laser therapy. Magnetic resonance imaging (MRI) was performed before treatment and at the 1-month follow-up...
June 8, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28601040/spectroscopic-parameters-of-the-low-lying-electronic-states-and-laser-cooling-feasibility-of-nh-cation-and-nh-anion
#15
Qing-Qing Zhang, Chuan-Lu Yang, Mei-Shan Wang, Xiao-Guang Ma, Wen-Wang Liu
The potential energy curves and transition dipole moments of 1(2)Σ(+), 2(2)Σ(+), 1(2)Π and 2(2)Π states of NH(+) cation and NH(-) anion are calculated by using multi-reference configuration interaction method and large all-electron basis sets. Based on the obtained potential energy curves, the rotational and vibrational energy levels of the states are obtained by solving the Schrödinger equation of nuclear movement. The calculated spectroscopic parameters for NH(+) cation and NH(-) anion are in good agreement with available theoretical and experimental results...
October 5, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28596787/clinical-usefulness-of-the-vs-classification-system-using-magnifying-endoscopy-with-blue-laser-imaging-for-early-gastric-cancer
#16
Yoshikazu Yoshifuku, Yoji Sanomura, Shiro Oka, Kazutaka Kuroki, Mio Kurihara, Takeshi Mizumoto, Yuji Urabe, Toru Hiyama, Shinji Tanaka, Kazuaki Chayama
BACKGROUND: Blue laser imaging (BLI) enables the acquisition of more information from tumors' surfaces compared with white light imaging. Few reports confirm the validity of magnifying endoscopy (ME) with BLI (ME-BLI) for early gastric cancer (EGC). We aimed to assess the detailed endoscopic findings from EGCs using ME-BLI. METHODS: We enrolled 386 consecutive patients with 417 EGCs that were diagnosed using ME-BLI and resected by endoscopic submucosal dissection...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28594941/low-level-laser-lll-attenuate-lps-induced-inflammatory-responses-in-mesenchymal-stem-cells-via-the-suppression-of-nf-%C3%AE%C2%BAb-signaling-pathway-in-vitro
#17
Kan Yin, Rongjia Zhu, Shihua Wang, Robert Chunhua Zhao
BACKGROUND: Considering promising results in animal models and patients, therapeutic use of MSCs for immune disease is likely to undergo continued evaluation. Low-lever laser (LLL) has been widely applied to retard the inflammatory reaction. LLL treatment can potentially be applied in anti-inflammatory therapy followed by stem cell therapy. AIM OF THE STUDY: The purpose of this study was to investigate the effect of LLL (660 nm) on the inflammatory reaction induced by LPS in human adipose derived mesenchymal stem cells (hADSCs) and pertinent mechanism...
2017: PloS One
https://www.readbyqxmd.com/read/28592995/the-quest-for-epigenetic-regulation-underlying-unisexual-flower-development-in-cucumis-melo
#18
David Latrasse, Natalia Y Rodriguez-Granados, Alaguraj Veluchamy, Kiruthiga Gayathri Mariappan, Claudia Bevilacqua, Nicolas Crapart, Celine Camps, Vivien Sommard, Cécile Raynaud, Catherine Dogimont, Adnane Boualem, Moussa Benhamed, Abdelhafid Bendahmane
BACKGROUND: Melon (Cucumis melo) is an important vegetable crop from the Cucurbitaceae family and a reference model specie for sex determination, fruit ripening and vascular fluxes studies. Nevertheless, the nature and role of its epigenome in gene expression regulation and more specifically in sex determination remains largely unknown. RESULTS: We have investigated genome wide H3K27me3 and H3K9ac histone modifications and gene expression dynamics, in five melon organs...
2017: Epigenetics & Chromatin
https://www.readbyqxmd.com/read/28586046/enhanced-effect-of-nuclear-localization-signal-peptide-during-ultrasound%C3%A2-targeted-microbubble-destruction%C3%A2-mediated-gene-transfection
#19
Sheng Cao, Qing Zhou, Jin-Ling Chen, Nan Jiang, Yi-Jia Wang, Qing Deng, Bo Hu, Rui-Qiang Guo
Ultrasound‑targeted microbubble destruction (UTMD) can promote the entry of plasmid DNA (pDNA) into the cell cytoplasm, by increasing the permeability of the cell membrane. But the transfection efficiency remains low due to inability of the pDNA to enter the nucleus. Various methods have been explored to improve the UTMD transfection efficiency, but with little success. In cells, the classic nuclear localization signal (cNLS) peptide is an amino acid sequence that signals proteins that are due for nuclear transport...
July 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28580494/efficacy-of-low-level-laser-therapy-in-carpal-tunnel-syndrome-management-a-systematic-review-and-meta-analysis
#20
Amira Hassan Bekhet, Basma Ragab, Abdelrahman Ibrahim Abushouk, Ahmed Elgebaly, Olfat Ibrahim Ali
We performed this meta-analysis to investigate the efficacy of low-level laser therapy (LLLT), a physiotherapy modality with anti-inflammatory and analgesic effects, in the management of mild-to-moderate carpal tunnel syndrome (CTS). We searched PubMed, Web of Knowledge, Scopus, Cochrane Central, and Virtual Health Library for randomized controlled trials (RCTs) that compared the effects of LLLT with or without splinting versus placebo on functional and electromyographic outcomes in CTS. All outcomes were pooled as mean differences (MD) under the inverse variance or random effects model, using the statistical add-in (MetaXL, version 5...
June 5, 2017: Lasers in Medical Science
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