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Clostridium difficile, VRE, HAND HYGIENE

Shelanah A Fernando, Timothy J Gray, Thomas Gottlieb
Healthcare-acquired infections (HAI) impact on patient care and have cost implications for the Australian healthcare system. The management of HAI is exacerbated by rising rates of antimicrobial resistance (AMR). Health-care workers and a contaminated hospital environment are increasingly implicated in the transmission and persistence of multi-resistant organisms (MRO), as well as other pathogens, such as Clostridium difficile. This has resulted in a timely focus on a range of HAI prevention actions. Core components include antimicrobial stewardship, to reduce overuse and ensure evidence-based antimicrobial use; infection prevention strategies, to control MRO - particularly methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus spp...
December 2017: Internal Medicine Journal
V Williams, A E Simor, A Kiss, A McGeer, Z Hirji, O E Larios, C Moore, K Weiss
A national point-prevalence survey for infection or colonization with methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-resistant Enterococcus (VRE), and for Clostridium difficile infection (CDI) was done in Canadian hospitals in 2010. A follow-up survey was done in November 2012 to determine whether there were any changes in the prevalence of these organisms; we also determined the prevalence of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae, and carbapenem-resistant Enterobacteriaceae (CREs)...
June 2015: Clinical Microbiology and Infection
Sudha P Jayaraman, Michael Klompas, Molli Bascom, Xiaoxia Liu, Regina Piszcz, Selwyn O Rogers, Reza Askari
BACKGROUND: Our institution had a major outbreak of multi-drug-resistant Acinetobacter (MDRA) in its general surgical and trauma intensive care units (ICUs) in 2011, requiring implementation of an aggressive infection-control response. We hypothesized that poor hand-hygiene compliance (HHC) may have contributed to the outbreak of MDRA. A response to the outbreak including aggressive environmental cleaning, cohorting, and increased hand hygiene compliance monitoring may have led to an increase in HHC after the outbreak and to a consequent decrease in the rates of infection by the nosocomial pathogens methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), and Clostridium difficile...
October 2014: Surgical Infections
Rhonda L Stuart, Despina Kotsanas, Brooke Webb, Susan Vandergraaf, Elizabeth E Gillespie, Geoffrey G Hogg, Tony M Korman
OBJECTIVE: To assess the frequency of, and risk factors for, colonisation with vancomycin-resistant enterococci (VRE), Clostridium difficile and extended-spectrum β-lactamase (ESBL)-producing organisms in residential aged care facilities (RACFs). DESIGN, SETTING AND PARTICIPANTS: We conducted a point prevalence survey in October-November 2010 in three RACFs associated with our health service. A single faecal sample was collected from each participating resident and screened for the presence of VRE, C...
November 7, 2011: Medical Journal of Australia
Gonzalo Bearman, Adriana E Rosato, Therese M Duane, Kara Elam, Kakotan Sanogo, Cheryl Haner, Valentina Kazlova, Michael B Edmond
OBJECTIVE: To compare the efficacy of universal gloving with emollient-impregnated gloves with standard contact precautions for the control of multidrug-resistant organisms (MDROs) and to measure the effect on healthcare workers' (HCWs') hand skin health. DESIGN: Prospective before-after trial. SETTING: An 18-bed surgical intensive care unit. METHODS: During phase 1 (September 2007 through March 2008) standard contact precautions were used...
May 2010: Infection Control and Hospital Epidemiology
Fred M Gordin, Maureen E Schultz, Ruth A Huber, Janet A Gill
OBJECTIVE: To assess quantitatively the clinical impact of using an alcohol-based handrub (ABHR) in the hospital environment, measuring impact as the incidence of new, nosocomial isolates of drug-resistant organisms. DESIGN: An observational survey from 1998 to 2003 comparing the first 3 years of no ABHR use with the 3 years following, when an ABHR was provided for hand hygiene. SETTING: An inner-city, tertiary-care medical center. INTERVENTION: At baseline, an antimicrobial soap with 0...
July 2005: Infection Control and Hospital Epidemiology
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