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Hulya Gungel, Cigdem Altan, Belma Karini, Fatma E Ozdemir, Ozlem O Celebi
PURPOSE: To present a case of a patient with contralateral vision loss as a result of Purtscher-like retinopathy after an endonasal dacryocystorhinostomy and treatment with intravitreal tissue plasminogen activator injection. METHODS AND RESULTS: A 51-year-old woman who underwent a left endonasal dacryocystorhinostomy was referred with a complaint of decreased vision 1 day after surgery in her right eye. At the initial examination, the visual acuity of her right eye was hand motion...
March 22, 2017: Retinal Cases & Brief Reports
Luiz H Lima, Silvana Vianello, Sérgio Pimentel, Gabriel Costa de Andrade, Claudio Zett, Léo Muller, Michel E Farah, Rubens Belfort
PURPOSE: To report the fundus manifestations and spectral-domain optical coherence tomographic (SD-OCT) features of dengue fever presenting as Purtscher-like retinopathy. METHODS: Retrospective review of two cases of dengue fever. RESULTS: Color fundus photograph revealed the presence of cotton-wool spots in a Purtscher-like configuration in the posterior pole of all study eyes. SD-OCT demonstrated increased reflectivity signal in the inner retinal layers, and after a variable follow-up period, there was complete disappearance of cotton-wool spots and persistence of the hyperreflectivity signal...
March 21, 2017: Ocular Immunology and Inflammation
J E Ramos de Carvalho, R O Schlingemann, M Oranje, F J Bemelman, M J van Schooneveld
Purtscher-like retinopathy, a rare manifestation of systemic thrombotic microangiopathy, is a potentially visually debilitating condition with no effective proven treatment. Distinct pathogenic pathways have been proposed as etiological factors. We revisit the etiology of Purtscher-like retinopathy based on the rapid response and profound visual improvement after initiation of systemic intravenous eculizumab, an inhibitor of the complement cascade, in a patient with Purtscher-like retinopathy secondary to familial atypical hemolytic uremic syndrome (aHUS) due to a mutation in complement factor H...
March 8, 2017: International Ophthalmology
Darren Shu Jeng Ting, Jonathan Smith, Stephen James Talks
PURPOSE: To describe a previously unreported case of Purtscher-like retinopathy secondary to severe acute renal failure associated with squamous cell carcinoma of the cervix. METHODS: This is a case report. RESULTS: A 31-year-old female presented with a week history of acute abdominal pain, vomiting and severe renal failure followed by a sudden onset of bilateral visual loss. Vision was hand movement in either eye with central scotoma. Ophthalmic examination demonstrated bilateral retinal thickening and whitening with intraretinal hemorrhages localized to the peripapillary area, consistent with the diagnosis of Purtscher-like retinopathy...
February 6, 2017: International Ophthalmology
Duosheng Xia, Xiaomei Chen, Qi Zhou, Shujun Xiao, Yang Yu, Yadong Wang, Gang Du, Haixiang Huang, Wenfang Zhang, Yaolong Chen
OBJECTIVE: The aim of this review is to evaluate the efficacy of available Purtscher's Retinopathy treatments. MATERIALS AND METHODS: In order to collect single-case reports, electronic searches were conducted in several databases including PubMed, Embase, Web of Science, China National Knowledge Infrastructure, SinoMed, VIP, and WanFang in the Electronic Theses and Dissertations Center. In VIP and Wanfang, we also traced the references of included articles. Risk of bias was evaluated using a tool adapted from the Cochrane Risk of Bias Tool...
January 31, 2017: Current Eye Research
Ralph Yachoui
PURPOSE: To describe clinical, laboratory, and funduscopic data of a patient presenting with newly diagnosed adult-onset Still disease and Purtscher-like retinopathy. METHODS: Observational case report. PATIENT: A 43-year-old man presented with a 3-week history of daily high-spiking fever, diffuse arthralgia and myalgia, sore throat, and a transient nonpruritic maculopapular rash. Two weeks from the onset of his illness, he developed a gradual decrease in visual acuity in both eyes...
January 2, 2017: Retinal Cases & Brief Reports
Wasim Md Mohosin Ul Haque, Mehruba Alam Ananna, Hasna Fahmima Haque, Muhammad Abdur Rahim, Tabassum Samad, Sarwar Iqbal
BACKGROUND: Purtscher's retinopathy and renal cortical necrosis are two rare vaso-occlusive complications of acute pancreatitis. Purtscher's retinopathy causes sudden impairment of vision, which was first reported in a patient with head trauma. Subsequently, it was also reported as a complication of acute pancreatitis and few other clinical conditions. Acute pancreatitis also rarely causes renal cortical necrosis leading to acute kidney injury. However, the simultaneous presence of both complications is rarely reported...
November 15, 2016: Journal of Medical Case Reports
Jaclyn L Kovach
PURPOSE: To report a case of Purtscher-like retinopathy associated with gemcitabine. METHODS: The author reports a 68-year-old woman who presented with a 4-month history of bilateral vision loss. She had a history of diabetes, hypertension, and leiomyosarcoma, diagnosed 5 months before presentation and had completed 5 cycles of combination treatment with gemcitabine and docetaxel. Clinical examination revealed a Purtscher-like retinopathy that improved after gemcitabine cessation without the development of cystoid macular edema or retinal neovascularization...
October 31, 2016: Retinal Cases & Brief Reports
Praveen Subudhi, Sanghamitra Kanungo, Nageswar Rao Subudhi
A 28-year-old man presented with a sudden onset of visual loss in both eyes (OU). He had a known history of acute pancreatitis and hepatitis following alcohol abuse. Examination of the anterior segment of the eye revealed non-sustained pupillary light reaction. The fundus showed typical Purtscher's flecken over the posterior pole with multiple cotton wool spots and retinal superficial haemorrhages in OU. Fundus fluorescein angiogram revealed abnormal hypofluorescence in both the posterior poles. Optical coherence tomography (OCT) for Purtscher's flecken showed abnormal retinal thickening with hyper-reflective areas in the inner neurosensory layers...
September 14, 2016: BMJ Case Reports
Cihan Buyukavsar, Ergenekon Karagoz, Murat Sonmez, Taner Kar, Abdullah Kaya, Eyup Düzgun, Yildiray Yildirim
Adult-onset Still's disease (AOSD) is a rare multisystemic immune-mediated disease of unknown etiology with quotidian spiking fever, evanescent rash, arthralgia, and multiple organ involvement. The few AOSD cases that have been reported developed Purtscher's-like retinopathy associated with thrombotic microangiopathy (TMA). Here, we report Purtscher's-like retinopathy without TMA in a patient with AOSD. A 29-year-old-man who presented for evaluation of blurred vision was diagnosed with AOSD based on Yamaguchi criteria...
September 6, 2016: Ocular Immunology and Inflammation
Azadeh Khatibi
PURPOSE: To report a case of Purtscher-like retinopathy with paracentral acute middle maculopathy preceded by febrile illness after filler injection into the buttock muscles bilaterally for cosmesis to achieve a "Brazilian booty." METHODS: Retrospective case report. RESULTS: A 35-year-old female presented with febrile illness and then decreased vision after repeat polymethyl methacrylate injections into her buttock muscles in Mexico. Examination was significant for retinal whitening, especially in the perifoveal areas, and intraretinal hemorrhages...
August 22, 2016: Retinal Cases & Brief Reports
Siddharth Narendran, V R Saravanan, Merlyn Pereira
Purtscher and Purtscher-like retinopathy is a distinctive retinal syndrome characterized by ischemic retinal whitening in a peripapillary pattern. We report a case of Purtscher-like retinopathy in a healthy 64-year-old man after a routine peribulbar anesthetic injection for cataract surgery. Although peribulbar anesthesia is considered to be a safer alternative to retrobulbar anesthesia, it has been associated with unusual but grave complications including central retinal artery occlusion.
June 2016: Indian Journal of Ophthalmology
Dov B Sebrow, Elona Dhrami-Gavazi, Jason D Horowitz, Lawrence A Yannuzzi
PURPOSE: The authors describe a woman diagnosed with hemophagocytic lymphohistiocytosis and found to have retinal examination findings consistent with Purtscher retinopathy. METHODS: A 52-year-old woman underwent multimodal imaging, including color fundus photography and spectral-domain optical coherence tomography, to confirm the diagnosis. RESULTS: The ophthalmic examination and imaging confirmed the findings of Purtscher retinopathy with significant inner retinal thickening on spectral-domain optical coherence tomography...
July 28, 2016: Retinal Cases & Brief Reports
Rehan M Hussain, Chi-Wah Yung
No abstract text is available yet for this article.
August 2016: Ophthalmology
Nitin Nema, Saba Ishrat, Abha Verma, Manoj Kela
A 23-year-old man with a history of alcoholism presented with vomiting, fever, and sharp epigastric pain radiating to the back and flanks. He was diagnosed as a case of acute alcoholic pancreatitis on the basis of clinical findings and investigations. On the next day of presentation, he developed sudden bilateral visual loss. His best-corrected visual acuity was finger counting at one-foot distance in both eyes. He had diffuse whitening in the circumpapillary area, haloes around the retinal vessels (Purtscher flecken) and intra-retinal hemorrhages on ophthalmoscopic examination...
May 2016: Oman Journal of Ophthalmology
Motoharu Tokimitsu, Masako Murata, Yuichi Toriyama, Takao Hirano, Yasuhiro Iesato, Toshinori Murata
BACKGROUND: Fat embolism in the deep retinal capillary plexus is one of the reported mechanisms underlying central/paracentral scotoma in patients with Purtscher's retinopathy. Here we report the clear delineation of capillary dropout in the deep capillary plexus using optical coherence tomography angiography (OCTA) in a chronic case of unexplained scotoma that developed after femoral fracture. The patient exhibited normal fluorescein angiography (FA) findings and a normal retinal appearance...
July 19, 2016: BMC Ophthalmology
Ahmed Chebil, Rym Mammouri, Mohamed Ben Abdallah, Leila El Matri
Purtscher's retinopathy is a rare condition that is noted in cases related to various types of trauma. The characteristic finding in the fundus is the presence of multiple Purtscher flecken. Purtscher-like retinopathy has a similar presentation in the fundus but is not associated with trauma. We report the case of a 55-year-old male who presented a severe visual loss during course of a hepatitis C infection. Ophthalmic examination indicated peripapillary cotton wool spots and superficial retinal whitening in the macula...
April 2016: Middle East African Journal of Ophthalmology
Bugra Karasu, Betul Onal Gunay, Gurkan Erdogan, Esra Kardes, Murat Gunay
A 21-year-old girl presented with acute painless vision loss in her right eye. There was no remarkable ocular history and she had a history of anorexia nervosa. At presentation best-corrected visual acuities were counting fingers from 2 meters and 20/20, in the right and left eyes, respectively. Slit lamp examination result was normal. Fundus examination revealed multiple cotton wool spots and intraretinal hemorrhages surrounding the optic disc and macula in the right eye. Fluorescein angiography showed capillary filling defect and leakage from optic disc in the late phase of the angiogram...
2016: Case Reports in Ophthalmological Medicine
Andreas Karwautz, Anna-Katharina Purtscher-Penz, Paulus Hochgatterer, Thomas Elstner, Gabriele Schöfbeck
No abstract text is available yet for this article.
March 2016: Neuropsychiatrie: Klinik, Diagnostik, Therapie und Rehabilitation
Reem M Alahmadi, Rotana T Hashim, Sultan M Almogairin, Ahmed M Abu
Systemic lupus erythematosus (SLE) is an autoimmune inflammatory disease, characterized by the involvement of multiple organ systems. Ocular involvement, being one of the manifestations, contributes to the assessment of disease activity. Purtscher-like retinopathy has been reported as a manifestation of SLE. An otherwise healthy 21-year old female presented with a bilateral rapid decrease in vision for 1 month. Fundus examination revealed multiple cotton wool spots and flame-shaped hemorrhages in both eyes...
January 2016: Annals of Saudi Medicine
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