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https://www.readbyqxmd.com/read/28651422/-meta-analysis-on-the-diagnostic-value-of-laser-doppler-imaging-for-burn-depth
#1
Y Huang, L Qiu, A L Mei, J X Li
Objective: To evaluate the value of laser Doppler imaging (LDI) in diagnosing deep or superficial partial-thickness burn wound with meta-analysis. Methods: Databases including PubMed, Cochrane Library were searched using key words " burn, burns, burn depth, laser Doppler imaging, laser Doppler perfusion imaging, LDI, LDPI" , and Chinese Journals Full-text Database, Wanfang Database, VIP Database were searched using Chinese key words ",,,," to obtain the published trials of LDI in diagnosing deep or superficial partial-thickness burn wound from the establishment of each database to October 2015...
May 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28651409/-drug-susceptibility-test-guided-therapy-and-novel-empirical-quadruple-therapy-for-helicobacter-pylori-infection-a-network-meta-analysis
#2
Q Y Gou, R B Yu, R H Shi
Objective: To compare the efficacy and the risk of adverse effect of drug susceptibility test guided therapy and novel empirical quadruple therapy for Helicobacter (H.) pylori infection. Methods: Literature retrieval was conducted by using major databases. Related papers published up to June 2015 were considered eligible if they were randomized control trials comparing different pharmacological formulations for H. pylori infection and used in a network Meta-analysis and a single rate Meta-analysis to evaluate the relative and absolute rates of H...
May 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28651386/optical-and-electrical-characteristics-of-silicon-nanowires-prepared-by-electroless-etching
#3
Sabar D Hutagalung, Mohammed M Fadhali, Raed A Areshi, Fui D Tan
Silicon nanowires (SiNWs) were fabricated by the electroless etching of an n-type Si (100) wafer in HF/AgNO3. Vertically aligned and high-density SiNWs are formed on the Si substrates. Various shapes of SiNWs are observed, including round, rectangular, and triangular. The recorded maximum reflectance of the SiNWs is approximately 19.2%, which is much lower than that of the Si substrate (65.1%). The minimum reflectance of the SiNWs is approximately 3.5% in the near UV region and 9.8% in the visible to near IR regions...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28651366/combining-fixed-effects-and-instrumental-variable-approaches-for-estimating-the-effect-of-psychosocial-job-quality-on-mental-health-evidence-from-13-waves-of-a-nationally-representative-cohort-study
#4
Allison Milner, Zoe Aitken, Anne Kavanagh, Anthony D LaMontagne, Frank Pega, Dennis Petrie
Background: Previous studies suggest that poor psychosocial job quality is a risk factor for mental health problems, but they use conventional regression analytic methods that cannot rule out reverse causation, unmeasured time-invariant confounding and reporting bias. Methods: This study combines two quasi-experimental approaches to improve causal inference by better accounting for these biases: (i) linear fixed effects regression analysis and (ii) linear instrumental variable analysis...
June 23, 2017: Journal of Public Health
https://www.readbyqxmd.com/read/28651359/altered-mirna-and-pirna-profiles-in-cumulus-cells-from-patients-with-diminished-ovarian-reserve
#5
Dawei Chen, Zhiguo Zhang, Beili Chen, Dongmei Ji, Yan Hao, Ping Zhou, Zhaolian Wei, Yunxia Cao
Diminished ovarian reserve (DOR) is defined as decreased number or quality of follicles and oocytes in a woman at childbearing age. It is estimated that up to 10% of women in the general population may suffer from DOR. The present study aims to comprehensively characterize miRNA and piRNA expression profiles in cumulus cells of DOR patients. Cumulus cells were collected from 20 women of similar chronological age who received assisted reproductive technology treatment, 10 with diminished ovarian reserve (DOR), 10 with normal ovarian reserve (NOR)...
June 23, 2017: Biology of Reproduction
https://www.readbyqxmd.com/read/28651296/early-discharge-hospital-at-home
#6
REVIEW
Daniela C Gonçalves-Bradley, Steve Iliffe, Helen A Doll, Joanna Broad, John Gladman, Peter Langhorne, Suzanne H Richards, Sasha Shepperd
BACKGROUND: Early discharge hospital at home is a service that provides active treatment by healthcare professionals in the patient's home for a condition that otherwise would require acute hospital inpatient care. This is an update of a Cochrane review. OBJECTIVES: To determine the effectiveness and cost of managing patients with early discharge hospital at home compared with inpatient hospital care. SEARCH METHODS: We searched the following databases to 9 January 2017: the Cochrane Effective Practice and Organisation of Care Group (EPOC) register, Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, Embase, CINAHL, and EconLit...
June 26, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28651217/modeling-in-sewer-transformations-at-catchment-scale-implications-on-drug-consumption-estimates-in-wastewater-based-epidemiology
#7
Ann-Kathrin McCall, Rocco Palmitessa, Frank Blumensaat, Eberhard Morgenroth, Christoph Ort
To which extent illicit drugs are transformed during in-sewer transport, depends on a number of factors: i) substance-specific transformation rates, ii) environmental conditions, iii) point of discharge (location of drug user) and iv) sewer network properties, primarily hydraulic residence time (HRT) and the ratio of biofilm contact area to wastewater volume (A/Veq). Assessing associated uncertainties typically requires numerous simulations. Therefore, we propose a new two-step modeling framework: 1) Quantify hydrodynamic conditions...
May 20, 2017: Water Research
https://www.readbyqxmd.com/read/28650811/regularized-spectral-log-difference-technique-for-ultrasonic-attenuation-imaging
#8
Andres L Coila, Roberto J Lavarello
The attenuation coefficient slope (ACS) has the potential to be used for tissue characterization and as a diagnostic ultrasound tool, hence complementing B-mode images. The ACS can be valuable for estimation of other ultrasound parameters such as the backscatter coefficient. There is a well-known trade-off between the precision of the estimated ACS values and the data block size used in spectral-based techniques such as the spectral log difference (SLD). This trade-off limits the practical usefulness of spectral-based attenuation imaging techniques...
June 26, 2017: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/28650513/return-to-work-after-work-related-stress-a-randomized-controlled-trial-of-a-work-focused-cognitive-behavioral-intervention
#9
Vita Ligaya Dalgaard, Kirstin Aschbacher, Johan Hviid Andersen, David John Glasscock, Morten Vejs Willert, Ole Carstensen, Karin Biering
Objectives This study aimed to evaluate the effect of a stress management intervention (SMI) on lasting return to work (RTW) among patients with work-related stress complaints. Methods Sickness benefit departments from three local municipalities referred patients on sick leave with work-related adjustment disorders or mild depression to the Department of Occupational Medicine, Regional Hospital West Jutland. A 2× randomization procedure allocated patients into one of three groups: intervention (N=58), control A (which received a clinical assessment; N=56), or control B (no assessment; N=49)...
June 26, 2017: Scandinavian Journal of Work, Environment & Health
https://www.readbyqxmd.com/read/28650480/lineage-specification-of-human-dendritic-cells-is-marked-by-irf8-expression-in-hematopoietic-stem-cells-and-multipotent-progenitors
#10
Jaeyop Lee, Yu Jerry Zhou, Wenji Ma, Wanwei Zhang, Arafat Aljoufi, Thomas Luh, Kimberly Lucero, Deguang Liang, Matthew Thomsen, Govind Bhagat, Yufeng Shen, Kang Liu
The origin and specification of human dendritic cells (DCs) have not been investigated at the clonal level. Through the use of clonal assays, combined with statistical computation, to quantify the yield of granulocytes, monocytes, lymphocytes and three subsets of DCs from single human CD34(+) progenitor cells, we found that specification to the DC lineage occurred in parallel with specification of hematopoietic stem cells (HSCs) to the myeloid and lymphoid lineages. This started as a lineage bias defined by specific transcriptional programs that correlated with the combinatorial 'dose' of the transcription factors IRF8 and PU...
June 26, 2017: Nature Immunology
https://www.readbyqxmd.com/read/28650213/visualisation-of-upper-limb-activity-using-spirals-a-new-approach-to-the-assessment-of-daily-prosthesis-usage
#11
Alix Chadwell, Laurence Kenney, Malcolm Granat, Sibylle Thies, John S Head, Adam Galpin
BACKGROUND: Current outcome measures used in upper limb myoelectric prosthesis studies include clinical tests of function and self-report questionnaires on real-world prosthesis use. Research in other cohorts has questioned both the validity of self-report as an activity assessment tool and the relationship between clinical functionality and real-world upper limb activity. Previously,(1) we reported the first results of monitoring upper limb prosthesis use. However, the data visualisation technique used was limited in scope...
June 1, 2017: Prosthetics and Orthotics International
https://www.readbyqxmd.com/read/28650203/how-efficacious-is-danshen-salvia-miltiorrhiza-dripping-pill-in-treating-angina-pectoris-evidence-assessment-for-meta-analysis-of-randomized-controlled-trials
#12
Yongliang Jia, Siu-Wai Leung
BACKGROUND: More than 230 randomized controlled trials (RCTs) of danshen dripping pill (DSP) and isosorbide dinitrate (ISDN) in treating angina pectoris after the first preferred reporting items for systematic reviews and meta-analyses-compliant comprehensive meta-analysis were published in 2010. Other meta-analyses had flaws in study selection, statistical meta-analysis, and evidence assessment. This study completed the meta-analysis with an extensive assessment of the evidence. METHODS: RCTs published from 1994 to 2016 on DSP and ISDN in treating angina pectoris for at least 4 weeks were included...
June 26, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28650195/mechanisms-underlying-mindfulness-based-addiction-treatment-versus-cognitive-behavioral-therapy-and-usual-care-for-smoking-cessation
#13
Claire Adams Spears, Donald Hedeker, Liang Li, Cai Wu, Natalie K Anderson, Sean C Houchins, Christine Vinci, Diana Stewart Hoover, Jennifer Irvin Vidrine, Paul M Cinciripini, Andrew J Waters, David W Wetter
OBJECTIVE: To examine cognitive and affective mechanisms underlying mindfulness-based addiction treatment (MBAT) versus cognitive-behavioral therapy (CBT) and usual care (UC) for smoking cessation. METHOD: Participants in the parent study from which data were drawn (N = 412; 54.9% female; 48.2% African American, 41.5% non-Latino White, 5.4% Latino, 4.9% other; 57.6% annual income <$30,000) were randomized to MBAT (n = 154), CBT (n = 155), or UC (n = 103). From quit date through 26 weeks postquit, participants completed measures of emotions, craving, dependence, withdrawal, self-efficacy, and attentional bias...
June 26, 2017: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/28650191/perceived-problem-solving-deficits-and-suicidal-ideation-evidence-for-the-explanatory-roles-of-thwarted-belongingness-and-perceived-burdensomeness-in-five-samples
#14
Carol Chu, Kristin L Walker, Ian H Stanley, Jameson K Hirsch, Jeffrey H Greenberg, M David Rudd, Thomas E Joiner
Perceived social problem-solving deficits are associated with suicide risk; however, little research has examined the mechanisms underlying this relationship. The interpersonal theory of suicide proposes 2 mechanisms in the pathogenesis of suicidal desire: intractable feelings of thwarted belongingness (TB) and perceived burdensomeness (PB). This study tested whether TB and PB serve as explanatory links in the relationship between perceived social problem-solving (SPS) deficits and suicidal thoughts and behaviors cross-sectionally and longitudinally...
June 26, 2017: Journal of Personality and Social Psychology
https://www.readbyqxmd.com/read/28650155/probing-interface-defects-in-top-gated-mos2-transistors-with-impedance-spectroscopy
#15
Peng Zhao, Angelica Azcatl, Yuri Y Gomeniuk, Pavel Bolshakov, Michael Schmidt, Stephen J McDonnell, Christopher L Hinkle, Paul K Hurley, Robert M Wallace, Chadwin Young
The electronic properties of the HfO2/MoS2 interface were investigated using multi-frequency capacitance-voltage (C-V) and current-voltage characterization of top gated MoS2 metal oxide semiconductor field effect transistors. The analysis was performed on few layer (5 - 10) MoS2 MOSFETs fabricated using photolithographic patterning with 13 nm and 8 nm HfO2 gate oxide layers formed by atomic layer deposition after in-situ UV-O3 surface functionalization. The impedance response of the HfO2/MoS2 gate stack indicates the existence of specific defects at the interface, which exhibited either a frequency dependent distortion similar to conventional Si MOSFETs with unpassivated silicon dangling bonds, or a frequency dispersion over the entire voltage range corresponding to depletion of the HfO2/MoS2 surface, consistent with interface traps distributed over a range of energy levels...
June 26, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28650060/an-adaptive-bias-hybrid-md-kmc-algorithm-for-protein-folding-and-aggregation
#16
Emanuel K Peter, Joan-Emma Shea
In this paper, we present a novel hybrid Molecular Dynamics/kinetic Monte Carlo (MD/kMC) algorithm and apply it to protein folding and aggregation in explicit solvent. The new algorithm uses a dynamical definition of biases throughout the MD component of the simulation, normalized in relation to the unbiased forces. The algorithm guarantees sampling of the underlying ensemble in dependency of one average linear coupling factor 〈α〉τ. We test the validity of the kinetics in simulations of dialanine and compare dihedral transition kinetics with long-time MD-simulations...
June 26, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28649993/kappa-opioid-receptor-activation-in-dopamine-neurons-disrupts-behavioral-inhibition
#17
Antony D Abraham, Harrison M Fontaine, Allisa J Song, Mackenzie M Andrews, Madison A Baird, Brigitte L Kieffer, Benjamin B Land, Charles Chavkin
The dynorphin/kappa opioid receptor (KOR) system has been previously implicated in the regulation of cognition, but the neural circuitry and molecular mechanisms underlying KOR-mediated cognitive disruption are unknown. Here, we used an operational test of cognition involving timing and behavioral inhibition and found that systemic KOR activation impairs performance of male and female C57BL/6 mice in the differential reinforcement of low response rates (DRL) task. Systemic KOR antagonism also blocked stress-induced disruptions of DRL performance...
June 26, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28649965/pawflim-reducing-bias-and-uncertainty-to-enable-lower-photon-count-in-flim-experiments
#18
Mauro Silberberg, Hernán E Grecco
Förster resonant energy transfer measured by fluorescence lifetime imaging microscopy (FRET-FLIM) is the method of choice for monitoring the spatio-temporal dynamics of protein interactions in living cells. To obtain an accurate estimate of the molecular fraction of interacting proteins requires a large number of photons, which usually precludes the observation of a fast process, particularly with time correlated single photon counting (TCSPC) based FLIM. In this work, we propose a novel method named pawFLIM (phasor analysis via wavelets) that allows the denoising of FLIM datasets by adaptively and selectively adjusting the desired compromise between spatial and molecular resolution...
June 26, 2017: Methods and Applications in Fluorescence
https://www.readbyqxmd.com/read/28649954/in-vitro-validation-of-coronary-ct-angiography-for-the-evaluation-of-complex-lesions
#19
Carlos Collet, Yoshinobu Onuma, Maik J Grundeken, Yosuke Miyazaki, Marcio Bittercourt, Pieter Kitslaar, Sadako Motoyama, Yukio Ozaki, Taku Asano, Jolanda J Wentzel, Geert J Streekstra, Patrick W Serruys, Robbert J de Winter, Nihls Planken
AIMS: To assess in vitro the diagnostic accuracy of computed tomography angiography (CTA) for the evaluation of complex coronary lesions. METHODS AND RESULTS: Five Plexiglas phantoms with three bifurcations lesions each were designed to mimic the anatomic variations and fractal phenomenon of the coronary tree. In addition, luminal stenosis were scaled up with increases of 10%. A third generation dual-source computed tomography was used. Automated quantitative CTA analysis was performed...
June 27, 2017: EuroIntervention
https://www.readbyqxmd.com/read/28649949/diagnostic-performance-of-a-lattice-boltzmann-based-method-for-fast-ct-fractional-flow-reserve
#20
Andreas Giannopoulos, Anji Tang, Yin Ge, Michael Cheezum, Michael Steigner, Shinichiro Fujimoto, Kanako Kumamaru, Dante Chiappino, Daniele Della Latta, Sergio Berti, Sara Chiappino, Frank Rybicki, Simone Melchionna, Dimitrios Mitsouras
AIMS: Fractional flow reserve (FFR) estimated from coronary computed tomography angiography (CT-FFR) offers non-invasive detection of lesion-specific ischemia. We developed and validated a fast CT-FFR algorithm utilizing the Lattice-Boltzmann Method for blood flow simulation (LBM CT-FFR). METHODS AND RESULTS: 64 patients from 3 institutions with clinically-indicated CTA and invasive FFR measurement were retrospectively analyzed. CT-FFR was performed using an on-site tool interfacing with a commercial Lattice-Boltzmann fluid dynamics cloud-based platform...
June 27, 2017: EuroIntervention
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