keyword
MENU ▼
Read by QxMD icon Read
search

High Value

keyword
https://www.readbyqxmd.com/read/29353434/prediction-of-progression-in-skull-base-meningiomas-additional-benefits-of-apparent-diffusion-coefficient-value
#1
Ching-Chung Ko, Sher-Wei Lim, Tai-Yuan Chen, Jeon-Hor Chen, Chien-Feng Li, Yow-Ling Shiue
A subset of benign (WHO grade I) skull base meningiomas show early progression/recurrence (P/R) in the first years after surgical resection. Besides, complete surgical resection may be difficult to achieve safely in skull base meningiomas due to complex neurovascular structures. The one main challenge in the treatment of skull base meningiomas is to determine factors that correlate with P/R. We retrospectively investigated the preoperative CT and MR imaging features for the prediction of P/R in skull base meningiomas, with emphasis on quantitative ADC values...
January 20, 2018: Journal of Neuro-oncology
https://www.readbyqxmd.com/read/29353417/maternal-metabolic-response-to-dietary-treatment-for-impaired-glucose-tolerance-and-gestational-diabetes-mellitus
#2
Karen L Lindsay, Lorraine Brennan, Maria A Kennelly, Sinéad Curran, Mary Coffey, Thomas P Smith, Michael E Foley, Mensud Hatunic, Fionnuala M McAuliffe
BACKGROUND: Dietary advice is a standard component of treatment for pregnant women with impaired glucose tolerance (IGT) and gestational diabetes (GDM), yet few studies report glycemic profiles in response to dietary therapies and the optimal dietary approach remains uncertain. AIM: To assess changes in maternal glycemic profile and pregnancy outcomes among women with diet-controlled IGT and GDM. METHODS: Pregnant women who had one or more elevated values on a 3-h oral glucose tolerance test were enrolled...
January 20, 2018: Irish Journal of Medical Science
https://www.readbyqxmd.com/read/29353377/highly-synergistic-activity-of-melittin-with-imipenem-and-colistin-in-biofilm-inhibition-against-multidrug-resistant-strong-biofilm-producer-strains-of-acinetobacter-baumannii
#3
Ali Mohammadi Bardbari, Mohammad Reza Arabestani, Manoochehr Karami, Fariba Keramat, Hossein Aghazadeh, Mohammad Yousef Alikhani, Kamran Pooshang Bagheri
The rapid increase of drug resistance and failure of available antibiotics to treat biofilm-associated infections is of great health concern. Accordingly, our study aimed to evaluate the synergistic antibacterial, biofilm inhibitory, and biofilm removal activities of melittin in combination with colistin, imipenem, and ciprofloxacin against multidrug-resistant (MDR) strong biofilm producer Acinetobacter baumannii isolates. The kinetics of biofilm formation were evaluated for the isolates for 144 h. Minimum inhibitory concentrations (MICs), minimum bactericidal concentrations (MBCs), minimum biofilm inhibitory concentrations (MBICs), and biofilm removal activities for melittin and combinations with antibiotics were determined...
January 20, 2018: European Journal of Clinical Microbiology & Infectious Diseases
https://www.readbyqxmd.com/read/29353328/serum-uric-acid-levels-are-associated-with-lupus-nephritis-in-patients-with-normal-renal-function
#4
Ana Luisa Calich, Eduardo Ferreira Borba, Michelle Remião Ugolini-Lopes, Luiza Fuoco da Rocha, Eloisa Bonfá, Ricardo Fuller
Uric acid has been recognised as a potential marker of endothelial dysfunction and kidney disease but there are scarce data about its importance in systemic lupus erythematosus (SLE) nephritis. This study aimed to evaluate serum uric acid (UA) levels in lupus nephritis (LN), by comparing SLE patients with normal renal function, with and without nephritis. Forty-six female SLE patients were consecutively selected and divided in two groups according to renal activity at the evaluation: presence of a recently diagnosed lupus nephritis (LN+, n = 18) and absence of lupus nephritis (LN-, n = 28)...
January 20, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29353326/radiological-and-functional-outcomes-of-high-grade-spondylolisthesis-treated-by-intrasacral-fixation-dome-resection-and-circumferential-fusion-a-retrospective-series-of-20-consecutive-cases-with-a-minimum-of-2%C3%A2-years-follow-up
#5
E Ferrero, B Ilharreborde, V Mas, C Vidal, A-L Simon, K Mazda
PURPOSE: Major concern during surgery for high-grade spondylolisthesis (HGS) is to reduce lumbosacral kyphosis and restore sagittal alignment. Despite the numerous methods described, lumbosacral fixation in HGS is a challenging technique associated with high complication rate. Few series have described outcomes and most of the results are limited to lumbosacral correction without global sagittal alignment analysis. This study aims at analyzing clinical and radiological outcomes of HGS patients treated with intrasacral rods on full spine radiographs...
January 20, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29353300/empirical-validation-of-the-crafft-abuse-screening-test-in-a-spanish-sample
#6
Antonio Rial, Sion Kim-Harris, John R Knight, Manuel Araujo, Patricia Gómez, Teresa Braña, Jesús Varela, Sandra Golpe
The CRAFFT Substance Abuse Screening Instrument, developed by the Center for Adolescents Substance Abuse Research (CeASAR) (Knight et al., 1999), is a screening tool for high-risk alcohol and drug risk consumption designed for use with adolescents. Since its publication it has been the subject of translations and validations in different countries, populations and contexts that have demonstrated its enormous potential. However, there is still no empirical validation study that would ensure its good psychometric performance in Spain...
January 15, 2018: Adicciones
https://www.readbyqxmd.com/read/29353299/creation-of-the-txp-parenting-questionnaire-and-study-of-its-psychometric-properties
#7
Ana Benito, Gema Calvo, Matías Real-López, María José Gallego, Sonia Francés, Ángel Turbi, Gonzalo Haro
Parenting is linked to conduct disorders (CD) and substance related disorders (SRD) in adolescents, but with differences according to cultural context. A questionnaire with two versions (parenting questionnaire TXP-A for adolescents and TXP-C  for primary caregivers) was designed using the Delphi method to evaluate parenting practices related to CD and SRD in a Spanish population. It was validated in a community sample of 631 adolescents aged between 14 and 16 and their caregivers. Results suggest a 29-item TXP-A questionnaire with bifactorial structure: affection-communication and control-structure, with high internal (Cronbach’s alpha=0...
January 15, 2018: Adicciones
https://www.readbyqxmd.com/read/29353289/the-new-agreement-of-the-international-riga-consensus-conference-on-nasal-airway-function-tests
#8
K Vogt, G Bachmann-Harildstad, A Lintermann, A Nechyporenko, F Peters, K D Wernecke
The report reflects an agreement based on the consensus conference of the International Standardization Committee on the Objective Assessment of the Nasal Airway in Riga, 2nd Nov. 2016. The aim of the conference was to address the existing nasal airway function tests and to take into account physical, mathematical and technical correctness as a base of international standardization as well as the requirements of the Council Directive 93/42/EEC of 14 June 1993 concerning medical devices. Rhinomanometry, acoustic rhinometry, peak nasal inspiratory flow, Odiosoft-Rhino, optical rhinometry, 24-h measurements, computational fluid dynamics, nasometry and the mirrow test were evaluated for important diagnostic criteria, which are the precision of the equipment including calibration and the software applied; validity with sensitivity, specificity, positive and negative predictive values, reliability with intra-individual and inter-individual reproducibility and responsiveness in clinical studies...
January 21, 2018: Rhinology
https://www.readbyqxmd.com/read/29353268/non-invasive-diagnostic-criteria-for-hepatocellular-carcinoma-in-hepatitis-b-virus-endemic-areas-is-cirrhosis-indispensable
#9
Xiao-Wen Huang, Bing Liao, Yang Huang, Jin-Yu Liang, Quan-Yuan Shan, Shun-Li Shen, Xiao-Yan Xie, Ming-de Lu, Li-da Chen, Wei Wang
AIM: To confirm whether cirrhosis is indispensable for the non-invasive diagnostic criteria for hepatocellular carcinoma (HCC) in hepatitis B virus (HBV)-endemic areas. METHODS: Between January 2014 and December 2014, a total of 409 patients with pathologically proven focal liver lesions who underwent contrast-enhanced ultrasound (CEUS) were recruited from our institution. Clinical liver cirrhosis, HBV/HCV infection and HCC-typical vascular pattern of the targeted lesion on CEUS were evaluated...
January 19, 2018: Digestive Diseases
https://www.readbyqxmd.com/read/29353261/impact-of-delivered-tidal-volume-on-the-occurrence-of-intraventricular-haemorrhage-in-preterm-infants-during-positive-pressure-ventilation-in-the-delivery-room
#10
Qaasim Mian, Po-Yin Cheung, Megan O'Reilly, Samantha K Barton, Graeme R Polglase, Georg M Schmölzer
BACKGROUND AND OBJECTIVES: Delivery of inadvertent high tidal volume (VT) during positive pressure ventilation (PPV) in the delivery room is common. High VT delivery during PPV has been associated with haemodynamic brain injury in animal models. We examined if VT delivery during PPV at birth is associated with brain injury in preterm infants <29 weeks' gestation. METHODS: A flow-sensor was placed between the mask and the ventilation device. VT values were compared with recently described reference ranges for VT in spontaneously breathing preterm infants at birth...
January 20, 2018: Archives of Disease in Childhood. Fetal and Neonatal Edition
https://www.readbyqxmd.com/read/29353199/applicability-of-kd-for-modelling-dissolved-137cs-concentrations-in-fukushima-river-water-case-study-of-the-upstream-ota-river
#11
Kazuyuki Sakuma, Hideki Tsuji, Seiji Hayashi, Hironori Funaki, Alex Malins, Kazuya Yoshimura, Hiroshi Kurikami, Akihiro Kitamura, Kazuki Iijima, Masaaki Hosomi
A study is presented on the applicability of the distribution coefficient (Kd) absorption/desorption model to simulate dissolved 137Cs concentrations in Fukushima river water. The upstream Ota River basin was simulated using GEneral-purpose Terrestrial Fluid-flow Simulator (GETFLOWS) for the period 1 January 2014 to 31 December 2015. Good agreement was obtained between the simulations and observations on water and suspended sediment fluxes, and on particulate bound 137Cs concentrations under both base and high flow conditions...
January 17, 2018: Journal of Environmental Radioactivity
https://www.readbyqxmd.com/read/29353196/high-adsorption-of-methylene-blue-by-salicylic-acid-methanol-modified-steel-converter-slag-and-evaluation-of-its-mechanism
#12
Min Cheng, Guangming Zeng, Danlian Huang, Cui Lai, Yang Liu, Chen Zhang, Rongzhong Wang, Lei Qin, Wenjing Xue, Biao Song, Shujing Ye, Huan Yi
A novel adsorbent based on steel converter slag (SCS), useful for adsorbing cationic pollutants from water was prepared by a simple method. The characterization showed that salicylic acid-methanol (SAM) modification selectively removed calcium silicate minerals from the surface of SCS and lead to a prominent increase in the specific surface areas. The maximum adsorption capacity of SAM-modified SCS for methylene blue (MB) at initial pH of 7.0 and temperature of 293 K was 41.62 mg/g, which is 35.2-times higher than that of SCS (1...
January 3, 2018: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/29353187/medication-use-in-a-cohort-of-newly-admitted-nursing-home-residents-ageing-nh-in-relation-to-evolving-physical-and-mental-health
#13
Ivana Ivanova, Maarten Wauters, Robert Vander Stichele, Thierry Christiaens, Jonas De Wolf, Tine Dilles, Monique Elseviers
BACKGROUND: Medication use is high among nursing home (NH) residents, but there is a lack of longitudinal studies, determining medication use at admission and its evolution over time. AIM: Describing the evolution of the medication use two years after entering a NH, compared to the baseline observations and exploring the relation to the physical and mental health. METHODS: Data from the observational prospective Ageing@NH study, based on an inception cohort of newly admitted residents at NHs (65+) was used, selecting those consenting and with medication chart available...
January 17, 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29353160/prediction-of-venous-thromboembolism-using-semantic-and-sentiment-analyses-of-clinical-narratives
#14
Susan Sabra, Khalid Mahmood Malik, Mazen Alobaidi
Venous thromboembolism (VTE) is the third most common cardiovascular disorder. It affects people of both genders at ages as young as 20 years. The increased number of VTE cases with a high fatality rate of 25% at first occurrence makes preventive measures essential. Clinical narratives are a rich source of knowledge and should be included in the diagnosis and treatment processes, as they may contain critical information on risk factors. It is very important to make such narrative blocks of information usable for searching, health analytics, and decision-making...
January 3, 2018: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29353074/diagnostic-value-of-human-papillomavirus-hpv-16-and-hpv18-viral-loads-for-the-detection-of-high-grade-cervical-intraepithelial-neoplasia-cin2-in-a-cohort-of-african-women-living-with-hiv
#15
Michel Segondy, Jean Ngou, Helen Kelly, Tanvier Omar, Olga Goumbri-Lompo, Sylviane Doutre, Philippe Mayaud, Marie-Noelle Didelot
BACKGROUND: African women living with HIV (WLHIV) are at high risk of cervical cancer but rarely adequately screened. Better strategies enabling identification of WLHIV with high-grade cervical intraepithelial lesions (CIN2+) are required. OBJECTIVES: To investigate the diagnostic value of HPV16 and HPV18 viral loads in a cohort of African WLHIV. DESIGN: HPV16 and HPV18 viral loads were determined by quantitation of the E6 gene DNA by real-time PCR in cervical specimens collected at baseline and endline (16 months) from 245 African WLHIV positive for HPV16 or/and HPV18...
January 16, 2018: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/29352993/comparison-of-chorioretinal-layers-in-rhesus-macaques-using-spectral-domain-optical-coherence-tomography-and-high-resolution-histological-sections
#16
Glenn Yiu, Zhe Wang, Christian Munevar, Eric Tieu, Bradley Shibata, Brittany Wong, David Cunefare, Sina Farsiu, Jeffrey Roberts, Sara Thomasy
Nonhuman primates are important preclinical models of retinal diseases because they uniquely possess a macula similar to humans. Ocular imaging technologies such as spectral-domain optical coherence tomography (SD-OCT) allow noninvasive, in vivo measurements of chorioretinal layers with near-histological resolution. However, the boundaries are based on differences in reflectivity, and detailed correlations with histological tissue layers have not been explored in rhesus macaques, which are widely used for biomedical research...
January 15, 2018: Experimental Eye Research
https://www.readbyqxmd.com/read/29352982/inhibition-of-cyp3a-by-antimalarial-piperaquine-and-its-metabolites-in-human-liver-microsomes-with-iviv-extrapolation
#17
Mohd Yusmaidie Aziz, Kurt-Jürgen Hoffmann, Michael Ashton
The potential of the antimalarial piperaquine and its metabolites to inhibit CYP3A was investigated in pooled human liver microsomes. CYP3A activity was measured by LC-MS/MS as the rate of 1'-hydroxymidazolam formation. Piperaquine was found to be a reversible, potent inhibitor of CYP3A with the following parameter estimates (%CV): IC50 = 0.76 μM (29), Ki = 0.68 μM (29). In addition, piperaquine acted as a time-dependent inhibitor (TDI) with IC50 declining to 0.32 μM (28) during 30 min pre-incubation. TDI estimates were kinact = 0...
January 15, 2018: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29352920/biomass-based-magnetic-fluorescent-nanoparticles-one-step-scalable-synthesis-application-as-drug-carriers-and-mechanism-study
#18
Lei Li, Feijun Wang, Ziqiang Shao
A biomass-based magnetic fluorescent nanoparticle (MFNPs) was successively in situ synthesized via a one-step high-gravity approach, which constructed by a magnetic core of Fe3O4 nanoparticles, the fluorescent marker of carbon dots (CDs), and shells of chitosan (CS). The obtained MFNPs had a 10 nm average diameter and narrow particle size distribution, low cytotoxicity, superior fluorescent emission and superparamagnetic properties. The encapsulating and release 5-fluorouracil experiments confirmed that the introduction of CS/CDs effectively improved the drug loading capacity...
March 15, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29352853/interferon-regulatory-factor-5-is-a-potential-target-of-autoimmune-response-triggered-by-epstein-barr-virus-and-mycobacterium-avium-subsp-paratuberculosis-in-rheumatoid-arthritis-investigating-a-mechanism-of-molecular-mimicry
#19
Marco Bo, Gian Luca Erre, Magdalena Niegowska, Marco Piras, Loredana Taras, Maria Giovanna Longu, Giuseppe Passiu, Leonardo A Sechi
OBJECTIVES: Rheumatoid arthritis (RA) is a chronic disease characterised by a pro-inflammatory cytokines linked erosive joint damage and by humoral and cellular response against a broad range of self-peptides. Molecular mimicry between Epstein-Barr virus (EBV), Mycobacterium avium subsp. paratuberculosis (MAP) and host peptides has long been regarded as an RA pathogenetic mechanism. Using bioinformatic analysis we identified high sequence homology among interferon regulatory factor 5 (IRF5), EBV antigen BOLF1 and MAP antigen MAP_4027...
January 15, 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29352841/predict-rheumatoid-arthritis-conversion-from-undifferentiated-arthritis-with-dynamic-contrast-enhanced-mri-and-laboratory-indexes
#20
Xinwei Lei, Huixia Li, Ying Zhan, Jin Qu
OBJECTIVES: To investigate the clinical value of dynamic contrast-enhanced MRI (DCE-MRI) and laboratory indexes in predicting conversion from undifferentiated arthritis (UA) to rheumatoid arthritis (RA). METHODS: A total 81 DMARD-naive UA patients were studied. 37 cases were ultimately diagnosed as RA, 32 cases were diagnosed as other types of arthritis, and the remaining cases were still UA during the 1-year follow-up. The DCE-MRI and laboratory measures were fed into a logistic regression analysis...
January 15, 2018: Clinical and Experimental Rheumatology
keyword
keyword
23478
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"