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https://www.readbyqxmd.com/read/28238599/service-review-improving-breast-cancer-care-in-tanzania
#1
Susan Mayor
No abstract text is available yet for this article.
February 23, 2017: Lancet Oncology
https://www.readbyqxmd.com/read/28237831/different-origin-and-dispersal-of-sulphadoxine-resistant-plasmodium-falciparum-haplotypes-between-eastern-africa-and-democratic-republic-of-congo
#2
Vito Baraka, Christopher Delgado-Ratto, Sidsel Nag, Deus S Ishengoma, Rashid A Madebe, Hypolite Muhindo Mavoko, Carolyn Nabasumba, Pascal Lutumba, Michael Alifrangis, Jean-Pierre Van Geertruyden
Sulphadoxine/pyrimethamine (SP) is still used for malaria control in sub-Saharan Africa; however, widespread resistance is a major concern. This study aimed to determine the dispersal and origin of sulphadoxine resistance lineages in the Democratic Republic of the Congo compared with East African Plasmodium falciparum dihydropteroate synthetase (Pfdhps) haplotypes. The analysis involved 264 isolates collected from patients with uncomplicated malaria from Tanzania, Uganda and DR Congo. Isolates were genotyped for Pfdhps mutations at codons 436, 437, 540, 581 and 613...
February 22, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28228134/the-impact-of-community-health-worker-led-home-delivery-of-antiretroviral-therapy-on-virological-suppression-a-non-inferiority-cluster-randomized-health-systems-trial-in-dar-es-salaam-tanzania
#3
Pascal Geldsetzer, Joel M Francis, Nzovu Ulenga, David Sando, Irene A Lema, Eric Mboggo, Maria Vaikath, Happiness Koda, Sharon Lwezaula, Janice Hu, Ramadhani A Noor, Ibironke Olofin, Elysia Larson, Wafaie Fawzi, Till Bärnighausen
BACKGROUND: Home delivery of antiretroviral therapy (ART) by community health workers (CHWs) may improve ART retention by reducing the time burden and out-of-pocket expenditures to regularly attend an ART clinic. In addition, ART home delivery may shorten waiting times and improve quality of care for those in facility-based care by decongesting ART clinics. This trial aims to determine whether ART home delivery for patients who are clinically stable on ART combined with facility-based care for those who are not stable on ART is non-inferior to the standard of care (facility-based care for all ART patients) in achieving and maintaining virological suppression...
February 22, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28222815/cognitive-stimulation-therapy-as-a-sustainable-intervention-for-dementia-in-sub-saharan-africa-feasibility-and-clinical-efficacy-using-a-stepped-wedge-design
#4
Stella-Maria Paddick, Sarah Mkenda, Godfrey Mbowe, Aloyce Kisoli, William K Gray, Catherine L Dotchin, Laura Ternent, Adesola Ogunniyi, John Kissima, Olaide Olakehinde, Declare Mushi, Richard W Walker
BACKGROUND: Cognitive stimulation therapy (CST) is a psychosocial group-based intervention for dementia shown to improve cognition and quality of life with a similar efficacy to cholinesterase inhibitors. Since CST can be delivered by non-specialist healthcare workers, it has potential for use in low-resource environments, such as sub-Saharan Africa (SSA). We aimed to assess the feasibility and clinical effectiveness of CST in rural Tanzania using a stepped-wedge design. METHODS: Participants and their carers were recruited through a community dementia screening program...
February 22, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28221960/mycotoxin-contamination-in-stored-maize-and-groundnuts-based-on-storage-practices-and-conditions-in-subhumid-tropical-africa-the-case-of-kilosa-district-tanzania
#5
K S Magembe, M W Mwatawala, D P Mamiro
Experiments were conducted to assess the influence of storage practices on mycotoxin incidences in stored maize and groundnuts in Kilosa District, Eastern Central Tanzania. Factorial experiments were used to test the effects of processing, storage conditions, and protectants at 3-month intervals for 12 weeks. Temperature and relative humidity data were recorded by using data loggers. The differences among the treatment means were compared using Tukey's honestly significant difference test at 5% probability level...
December 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28221939/load-and-prevalence-of-antimicrobial-resistant-escherichia-coli-from-fresh-goat-meat-in-arusha-tanzania
#6
Gaspary Mwanyika, Douglas R Call, Benardether Rugumisa, Catherine Luanda, Rehema Murutu, Murugan Subbiah, Joram Buza
Given the potential public health risks associated with a burgeoning goat meat industry in Tanzania, we estimated the load of Escherichia coli and the prevalence of antibiotic-resistant strains for goat meat by using a cross-sectional study design (June to July 2015). Five large (n = 60 samples) and five small (n = 64 samples) slaughterhouses were sampled over a period of four to six visits each. Meat rinsate was prepared and plated onto MacConkey agar, and presumptive E. coli colonies were enumerated and reported as CFU per milliliter of rinsate...
September 2016: Journal of Food Protection
https://www.readbyqxmd.com/read/28219321/genetic-characterization-of-vibrio-cholerae-o1-isolates-from-outbreaks-between-2011-and-2015-in-tanzania
#7
Yazid Kachwamba, A A Mohammed, H Lukupulo, L Urio, M Majigo, F Mosha, M Matonya, R Kishimba, J Mghamba, J Lusekelo, S Nyanga, M Almeida, S Li, D Domman, S Y Massele, O C Stine
BACKGROUND: Cholera outbreaks have occurred in Tanzania since 1974. To date, the genetic epidemiology of these outbreaks has not been assessed. METHODS: 96 Vibrio cholerae O1 isolates from five regions were characterized, and their genetic relatedness assessed using multi-locus variable-number tandem-repeat analysis (MLVA) and whole genome sequencing (WGS). RESULTS: Of the 48 MLVA genotypes observed, 3 were genetically unrelated to any others, while the remaining 45 genotypes separated into three MLVA clonal complexes (CCs) - each comprised of genotypes differing by a single allelic change...
February 20, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28217265/rubella-seromarkers-and-determinants-of-infection-among-tanzanian-children-and-adolescents-in-prevaccination-era-are-we-in-the-right-track
#8
Mariam M Mirambo, Said Aboud, Uwe Groß, Mtebe Majigo, Martha F Mushi, Stephen E Mshana
BACKGROUND: The World health organization advocates assessment of the burden of rubella and congenital rubella syndrome (CRS) by seroepidemiological surveys and surveillance programs in all countries without vaccination programs. Due to scarcity of data in developing countries, this study was conducted to assess the seromakers for natural rubella infection in Tanzania during prevaccination era so as to ascertain the gaps for future research and prevention strategies. METHODS: A cross-sectional study was conducted between September and October 2014...
2017: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/28216188/rationale-and-support-for-a-one-health-program-for-canine-vaccination-as-the-most-cost-effective-means-of-controlling-zoonotic-rabies-in-endemic-settings
#9
REVIEW
Robert P Lavan, Alasdair I MacG King, David J Sutton, Kaan Tunceli
Although dog vaccination has been demonstrated to reduce and eliminate rabies in humans, during meetings there are often calls for further pilot studies. The assembled data proves that a widespread approach is now required. While zoonotic rabies has a minimal presence in developed nations, it is endemic throughout most of Asia and Africa, where it is considered to be a neglected tropical disease. In these areas, rabies causes an estimated annual mortality of at least 55,000 human deaths. Worldwide rabid dogs are the source of the vast majority of human rabies exposures...
February 16, 2017: Vaccine
https://www.readbyqxmd.com/read/28215871/disease-behaviours-of-sows-naturally-infected-with-taenia-solium-in-tanzania
#10
Chiara Trevisan, Maria Vang Johansen, Ernatus Martin Mkupasi, Helena Aminel Ngowi, Björn Forkman
Neurocysticercosis (NCC) is a disease caused by the zoonotic parasite Taenia solium lodging in the central nervous system. Both humans and pigs can get NCC. The impact of the disease in pigs has so far been little explored. The aim of this study was to describe the effect of NCC on social and feeding behaviours as well as the pattern of activity as indicators of reduced welfare in naturally infected sows. In total 13 T. solium naturally infected and 15 non-infected control sows were videotaped for 2 consecutive weeks using close circuit television cameras at research facilities at Sokoine University of Agriculture, Morogoro, Tanzania...
February 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/28215715/multidrug-resistant-achromobacter-animicus-causing-wound-infection-in-a-street-child-in-mwanza-tanzania
#11
Nyambura Moremi, Heike Claus, Marko Hingi, Ulrich Vogel, Stephen E Mshana
Achromobacter animicus (A. animicus) is an aerobic, motile, gram-negative, non-fermenting small bacillus that can also grow anaerobically with potassium nitrate. It has been isolated from sputum of humans suffering from respiratory infections. Literature regarding the role of A. animicus in wound infections is limited. We report a first case of a chronic post-traumatic wound infection caused by a multidrug-resistant A. animicus in a street child from Africa and accompanied diagnostic challenges.
February 10, 2017: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/28214093/educating-religious-leaders-to-promote-uptake-of-male-circumcision-in-tanzania-a-cluster-randomised-trial
#12
Jennifer A Downs, Agrey H Mwakisole, Alphonce B Chandika, Shibide Lugoba, Rehema Kassim, Evarist Laizer, Kinanga A Magambo, Myung Hee Lee, Samuel E Kalluvya, David J Downs, Daniel W Fitzgerald
BACKGROUND: Male circumcision is being widely deployed as an HIV prevention strategy in countries with high HIV incidence, but its uptake in sub-Saharan Africa has been below targets. We did a study to establish whether educating religious leaders about male circumcision would increase uptake in their village. METHODS: In this cluster randomised trial in northwest Tanzania, eligible villages were paired by proximity (<60 km) and the time that a free male circumcision outreach campaign from the Tanzanian Ministry of Health became available in their village...
February 14, 2017: Lancet
https://www.readbyqxmd.com/read/28212636/experimental-hut-evaluation-of-a-novel-long-lasting-non-pyrethroid-durable-wall-lining-for-control-of-pyrethroid-resistant-anopheles-gambiae-and-anopheles-funestus-in-tanzania
#13
Robert Malima, Basiliana Emidi, Louisa A Messenger, Richard M Oxborough, Bernard Batengana, Wema Sudi, Sophie Weston, George Mtove, Joseph P Mugasa, Franklin W Mosha, Mark W Rowland, William Kisinza
BACKGROUND: A novel, insecticide-treated, durable wall lining (ITWL), which mimics indoor residual spraying (IRS), has been developed to provide prolonged vector control when fixed to the inner walls of houses. PermaNet(®) ITWL is a polypropylene material containing non-pyrethroids (abamectin and fenpyroximate) which migrate gradually to the surface. METHODS: An experimental hut trial was conducted in an area of pyrethroid-resistant Anopheles gambiae s.l. and Anopheles funestus s...
February 17, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28210845/whipworm-diversity-in-west-african-rodents-a-molecular-approach-and-the-description-of-trichuris-duplantieri-n-sp-nematoda-trichuridae
#14
Alexis Ribas, Christophe Diagne, Caroline Tatard, Mamoudou Diallo, Srisupaph Poonlaphdecha, Carine Brouat
Whipworms were collected from rodents (Muridae) from six West African countries: Burkina-Faso, the Islamic Republic of Mauritania, and the Republics of Benin, Guinea, Mali and Senegal. Molecular sequences (ITS-1, 5.8S and ITS-2 of the ribosomal DNA gene) and morphometric characters were analysed in Trichuris (Nematoda: Trichuridae) specimens found in seven host species: Arvicanthis niloticus, Gerbilliscus gambianus, Gerbillus gerbillus, G. tarabuli, Mastomys erythroleucus, M. huberti and M. natalensis. Phylogenetic analyses revealed three clades, one recognised as Trichuris mastomysi, previously recorded in M...
February 16, 2017: Parasitology Research
https://www.readbyqxmd.com/read/28208218/antibiotic-resistance-in-escherichia-coli-in-husbandry-animals-the-african-perspective
#15
REVIEW
Carla Andrea Alonso, Myriam Zarazaga, Rym Ben Sallem, Ahlem Jouini, Karim Ben Slama, Carmen Torres
In the last years different surveillances have been published in Africa, especially in Northern countries, regarding antimicrobial resistance among husbandry animals. Information is still scarce, but the available data shows a worrying picture. Although the highest resistance rates have been described against tetracycline, penicillins and sulphonamides, prevalence of plasmid mediated quinolone resistance genes and extended-spectrum β-lactamase (ESBL) are being increasingly reported. Among ESBLs, the CTX-M-1 group was dominant in most African surveys, being CTX-M-15 the main variant both in animals and humans, except in Tunisia where CTX-M-1 was more frequently detected among E...
February 16, 2017: Letters in Applied Microbiology
https://www.readbyqxmd.com/read/28207686/notes-from-the-field-ongoing-cholera-epidemic-tanzania-2015-2016
#16
Rupa Narra, Justin M Maeda, Herilinda Temba, Janneth Mghamba, Ali Nyanga, Ashley L Greiner, Muhammad Bakari, Karlyn D Beer, Sae-Rom Chae, Kathryn G Curran, Rachel B Eidex, James J Gibson, Thomas Handzel, Stephen J Kiberiti, Rogath S Kishimba, Haji Lukupulo, Theophil Malibiche, Khalid Massa, Amani E Massay, Lindsey S McCrickard, Geofrey J Mchau, Vida Mmbaga, Ahmed A Mohamed, Elibariki R Mwakapeje, Emmanuel Nestory, Anna E Newton, Elvis Oyugi, Anu Rajasingham, Michelle E Roland, Neema Rusibamayila, Senga Sembuche, Loveness J Urio, Tiffany A Walker, Alice Wang, Robert E Quick
No abstract text is available yet for this article.
February 17, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28202736/hiv-and-sti-s-among-men-who-have-sex-with-men-in-dodoma-municipality-tanzania-a-cross-sectional-study
#17
Elia John Mmbaga, Kåre Moen, Neema Makyao, Rose Mpembeni, Melkizedeck T Leshabari
OBJECTIVES: To determine the seroprevalence of HIV, STI and related risks among men who have sex with men (MSM) in Dodoma municipality, Tanzania. METHODS: A cross-sectional study using respondent-driven sampling was employed to recruit study participants aged 18 years and above. Data on sociodemographics, HIV/STI knowledge and sexual practices were collected. Blood samples were tested for HIV and selected STIs. RESULTS: A total of 409 participants aged from 18 to 60 years took part in this study...
February 15, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28202309/working-in-scarcity-effects-on-social-interactions-and-biomedical-care-in-a-tanzanian-hospital
#18
Adrienne E Strong
Based on mixed-methods, ethnographic research in government health facilities conducted in Rukwa, Tanzania over 23 months between 2012 and 2015, this paper explores the social implications of budget shortfalls in the healthcare system at the level of a regional hospital. Budget crises resulted from the late disbursal of funds and the failure of outside donors to meet aid commitments needed to subsidize healthcare at the national level. Healthcare administrators recounted specific donors who pulled out of commitments as a direct result of foreign government austerity measures enacted after the global financial crisis of 2008...
February 7, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28196346/organochlorine-pesticides-ocps-and-polychlorinated-biphenyls-pcbs-in-human-breast-milk-and-associated-health-risks-to-nursing-infants-in-northern-tanzania
#19
M H B Müller, A Polder, O B Brynildsrud, M Karimi, E Lie, W B Manyilizu, R H Mdegela, F Mokiti, M Murtadha, H E Nonga, J U Skaare, J L Lyche
This is the first study to report organochlorines (OCs), including chlorinated pesticides (OCPs) and polychlorinated biphenyls (PCBs) in human milk from Tanzania. The main aims of this study were to assess the level of contamination and the possible health risks related to OC exposure in nursing infants from the Northern parts of Tanzania. Ninety-five healthy mother-infant couples attending Mount Meru Regional Referral Hospital (MMRRH), Arusha, Tanzania, were assessed for associations between maternal/infant characteristics, i...
April 2017: Environmental Research
https://www.readbyqxmd.com/read/28193398/incidence-of-invasive-salmonella-disease-in-sub-saharan-africa-a-multicentre-population-based-surveillance-study
#20
Florian Marks, Vera von Kalckreuth, Peter Aaby, Yaw Adu-Sarkodie, Muna Ahmed El Tayeb, Mohammad Ali, Abraham Aseffa, Stephen Baker, Holly M Biggs, Morten Bjerregaard-Andersen, Robert F Breiman, James I Campbell, Leonard Cosmas, John A Crump, Ligia Maria Cruz Espinoza, Jessica Fung Deerin, Denise Myriam Dekker, Barry S Fields, Nagla Gasmelseed, Julian T Hertz, Nguyen Van Minh Hoang, Justin Im, Anna Jaeger, Hyon Jin Jeon, Leon Parfait Kabore, Karen H Keddy, Frank Konings, Ralf Krumkamp, Benedikt Ley, Sandra Valborg Løfberg, Jürgen May, Christian G Meyer, Eric D Mintz, Joel M Montgomery, Aissatou Ahmet Niang, Chelsea Nichols, Beatrice Olack, Gi Deok Pak, Ursula Panzner, Jin Kyung Park, Se Eun Park, Henintsoa Rabezanahary, Raphaël Rakotozandrindrainy, Tiana Mirana Raminosoa, Tsiriniaina Jean Luco Razafindrabe, Emmanuel Sampo, Heidi Schütt-Gerowitt, Amy Gassama Sow, Nimako Sarpong, Hye Jin Seo, Arvinda Sooka, Abdramane Bassiahi Soura, Adama Tall, Mekonnen Teferi, Kamala Thriemer, Michelle R Warren, Biruk Yeshitela, John D Clemens, Thomas F Wierzba
BACKGROUND: Available incidence data for invasive salmonella disease in sub-Saharan Africa are scarce. Standardised, multicountry data are required to better understand the nature and burden of disease in Africa. We aimed to measure the adjusted incidence estimates of typhoid fever and invasive non-typhoidal salmonella (iNTS) disease in sub-Saharan Africa, and the antimicrobial susceptibility profiles of the causative agents. METHODS: We established a systematic, standardised surveillance of blood culture-based febrile illness in 13 African sentinel sites with previous reports of typhoid fever: Burkina Faso (two sites), Ethiopia, Ghana, Guinea-Bissau, Kenya, Madagascar (two sites), Senegal, South Africa, Sudan, and Tanzania (two sites)...
March 2017: Lancet Global Health
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