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https://www.readbyqxmd.com/read/29785332/dermoscopic-changes-in-melanocytic-nevi-covered-with-both-opaque-tape-and-sunscreen-cream-during-narrowband-ultraviolet-b-therapy
#1
Derya Ök Kekeç, Nida Kaçar, Işıl Kılınç Karaarslan
Background: Ultraviolet (UV) light may cause dermoscopic changes on melanocytic nevi (MN). Objectives: To investigate the effects of sunscreen cream (SSc) application on dermoscopic changes in MN during narrowband UVB (NBUVB) therapy. Methods: Half of the randomly selected MN in each patient were covered with opaque tape and SSc [SSc(+)], and the rest were covered with only opaque tape [SSc(-)] during NBUVB treatment sessions. Results: More SSc(-) MN displayed dermoscopic changes at end of NBUVB therapy compared to the start of therapy (p=0...
April 2018: Dermatology Practical & Conceptual
https://www.readbyqxmd.com/read/29777857/study-of-the-influence-of-substrate-and-spectrophotometer-characteristics-on-the-in-vitro-measurement-of-sunscreens-efficiency
#2
C Couteau, A Philippe, M-A Vibet, E Paparis, L Coiffard
All the methods used for the in vitro measurement of the SPF, the universal indicator of sunscreens efficiency, rely on a spectrophotometric analysis. What can vary about the experimental protocol used is mainly the substrate and the type of spectrophotometer chosen. We decided to work with polymethylmetacrylate plates that we analyzed using two spectrophotometers equipped with integrating spheres, the UV1000S and the UV2000 apparatus. Two marketed products were such tested, after spreading 2 mg/cm2 on the plates, using one apparatus after another...
May 16, 2018: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29774604/plant-sunscreen-and-co-ii-iii-porphyrins-for-uv-resistant-and-thermally-stable-perovskite-solar-cells-from-natural-to-artificial
#3
Jing Cao, Xudong Lv, Peng Zhang, Tracy T Chuong, Binghui Wu, Xiaoxia Feng, Changfu Shan, Jiacheng Liu, Yu Tang
The poor UV, thermal, and interfacial stability of perovskite solar cells (PSCs) makes it highly challenging for their technological application, and has drawn increasing attention to resolving the above issues. In nature, plants generally sustain long exposure to UV illumination without damage, which is attributed to the presence of the organic materials acting as sunscreens. Inspired by the natural phenomenon, a natural plant sunscreen, sinapoyl malate, an ester derivative of sinapic acid, is employed to modify the surface of electron transport materials (ETMs)...
May 17, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29772259/photocatalytic-production-of-hydroxyl-radicals-by-commercial-tio-2-nanoparticles-and-phototoxic-hazard-identification
#4
Ying Tang, Rui Cai, Ding Cao, Xue Kong, Yongbo Lu
This study identifies the phototoxic potential of commercial titanium dioxide nanoparticles (TiO2 NPs) used in sunscreens and consumer products by employing a tiered testing approach comprising physicochemical, in vitro and ex vivo tests. Our results revealed that all the test samples of TiO2 NPs, varied in surface coating, crystallinity and primary particle size, produced hydroxyl radicals upon UVA photoexcitation as determined by electron spin resonance (ESR) spectroscopy. Their phototoxic potentials were assessed first by combining the validated 3T3 neutral red uptake phototoxicity test and red blood cell phototoxicity test and subsequently in ex vivo models of chick chorioallantoic membrane (CAM) and reconstructed human 3D skin model (H3D)...
May 14, 2018: Toxicology
https://www.readbyqxmd.com/read/29755960/long-sun-exposures-influencing-high-sub-cutaneous-synthesis-of-vitamin-d3-may-be-associated-with-exacerbation-of-symptoms-in-allergic-asthma
#5
L G D'Cruz, S A Husain, T Wells, C Morgan, P J Stanczyk, A Satgunarajah, J Kashir, B L Calver, L M Blayney, F A Lai
Objectives: Does excessive sun-exposure, non-use of sunscreen and/or high doses of vitamin-D3 supplements provoke exacerbation of asthma? Design: Clinical examinations, retrospective records-access and questionnaire surveys were distributed to a convenience sample of allergic-asthma patient (n=183). Setting: Patients (19-89 years) attending the outpatient respiratory clinics at Maidstone Hospital were enrolled. Results: 90...
March 26, 2018: Journal of Aging Research & Clinical Practice
https://www.readbyqxmd.com/read/29755206/epilithic-chamaesiphon-synechococcales-cyanobacteria-species-in-mountain-streams-of-the-alps-interspecific-differences-in-photo-physiological-traits
#6
Siegfried Aigner, Klaus Herburger, Andreas Holzinger, Ulf Karsten
Many alpine streams inhabit conspicuous epilithic biofilms on pebbles and rocks that are formed by members of the cyanobacterial genus Chamaesiphon (Synechococcales). In the Austrian Alps, some Chamaesiphon species can even overgrow up to 70% of the surface of river rocks, and hence they must play an important but still unstudied ecological role in the organic matter flux. Since photo-biological traits have not been investigated so far, photosynthetic features, pigments, and UV-sunscreen compounds were studied in three Chamaesiphon morphospecies ( C...
2018: Journal of Applied Phycology
https://www.readbyqxmd.com/read/29752541/stratum-corneum-substantivity-drug-development-implications
#7
REVIEW
Becky S Li, John Havens Cary, Howard I Maibach
There are at least 15 factors that influence the ability of chemicals to penetrate the skin. Substantivity is yet another factor and allows penetrants to remain on and in skin for many days. As many skin pathologies involve stratum corneum and require multiple dosing of topicals, understanding substantivity mechanisms may provide insight for topical dosing strategies. Substantivity is also of importance in the development of other consumer products that necessitate adherence to skin, including sunscreens, insect repellents, and cosmetics...
May 11, 2018: Archives of Dermatological Research
https://www.readbyqxmd.com/read/29751729/unravelling-the-photoprotection-properties-of-mycosporine-amino-acid-motifs
#8
Jack Matthew Woolley, Michael Staniforth, Michael D Horbury, Gareth W Richings, Martin Wills, Vasilios G Stavros
Photoprotection from harmful ultraviolet (UV) radiation exposure is a key problem in modern society. Mycosporine like amino acids found in fungi, cyanobacteria, macroalgae, phytoplankton and humans, are already presenting a promising form of natural photoprotection in sunscreen formulations. Using time-resolved transient electronic absorption spectroscopy and guided by complementary ab initio calculations, we help to unravel how the core structures of these molecules perform under UV irradiation. Through such detailed insight into the relaxation mechanisms of these ubiquitous molecules, we hope to inspire new thinking in developing next generation sun protecting molecules...
May 11, 2018: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/29746427/risk-factors-for-basal-cell-carcinoma-in-men-younger-than-40-years-a-case-control-study
#9
Kathleen M Nemer, Tyler M Bauman, Alan S Boyd
BACKGROUND: Basal cell carcinoma (BCC) is the most common malignancy in the United States and is more prevalent in older populations. OBJECTIVE: The aim of this study was to investigate BCC risk factors in male patients younger than 40 years. MATERIALS AND METHODS: A consecutive series of male patients with pathology-proven BCC and younger than 40 years at time of diagnosis were retrospectively identified along with matched controls. Phone interviews were conducted using a structured questionnaire, and differences between patients with and without BCC were investigated...
May 9, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29734525/zinc-containing-compounds-for-personal-care-applications
#10
REVIEW
Michał Abendrot, Urszula Kalinowska-Lis
It is well known that zinc ions are widely used in cosmetic products. Their popularity is associated with the multifunctional profile of Zn2+ , which is classified as an essential chemical element in the human body. This review examines numerous beneficial biological properties of zinc-containing compounds and classifies the compounds used in cosmetic products according to their functionality profile: antioxidant, sunscreen, anti-inflammatory, anti-pigmentation, anti-aging, anti-acne, antimicrobial, anti-odour, cleansing or stabilising activity...
May 7, 2018: International Journal of Cosmetic Science
https://www.readbyqxmd.com/read/29733408/a-functional-near-infrared-spectroscopy-fnirs-replication-of-the-sunscreen-persuasion-paradigm
#11
Shannon M Burns, Lianne Barnes, Perri L Katzman, Daniel L Ames, Emily B Falk, Matthew D Lieberman
Activity in medial prefrontal cortex (mPFC) during persuasive messages predicts future message-consistent behavior change, but there are significant limitations to the types of persuasion processes that can be invoked inside an MRI scanner. For instance, real world persuasion often involves multiple people in conversation. Functional near infrared spectroscopy (fNIRS) allows us to move out of the scanner and into more ecologically valid contexts. As a first step, the current study used fNIRS to replicate an existing fMRI persuasion paradigm (i...
May 4, 2018: Social Cognitive and Affective Neuroscience
https://www.readbyqxmd.com/read/29731629/nanosized-titanium-dioxide-induced-premature-ovarian-failure-is-associated-with-abnormalities-in-serum-parameters-in-female-mice
#12
Fashui Hong, Ling Wang
Background: Exposure to titanium dioxide nanoparticles (TiO2 NPs) that are widely used in food, medicine, sunscreen products and cosmetics is reported to cause ovarian damage and lower fertility in animals. However, the potential effects of TiO2 NPs application on premature ovarian failure (POF) have rarely been evaluated to date. Methods: In this study, female mice were continuously exposed to TiO2 NPs at doses of 2.5, 5 or 10 mg/kg via gavage instillation for 30 days, and investigated the serum hormones and autoimmunity markers associated with POF...
2018: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29731179/parents-adherence-to-pediatric-health-and-safety-guidelines-importance-of-patient-provider-relationships
#13
Lindsay N Fuzzell, A Scott LaJoie, Kyle T Smith, Sydney E Philpott, Katherine M Jones, Mary C Politi
OBJECTIVE: To examine 1) parent-provider communication about pediatric health/safety guidelines, 2) trust in child's provider, 3) comfort discussing guidelines, 4) agreement with guideline advice, 5) self-efficacy following guidelines, and their impact on guideline adherence. METHOD: 256 parents of children ages 0-6 completed an online survey about sunscreen use, newborn Vitamin K injections, influenza vaccination, routine vaccination, car seats, infant safe sleep, furniture anchoring, large trampoline use, and firearm safety...
May 1, 2018: Patient Education and Counseling
https://www.readbyqxmd.com/read/29729069/ectoine-a-compatible-solute-in-radio-halophilic-stenotrophomonas-sp-wma-lm19-strain-to-prevent-ultraviolet-induced-protein-damage
#14
Wasim Sajjad, Sundas Qadir, Manzoor Ahmad, Muhammad Rafiq, Fariha Hasan, Richard Tehan, Kerry L McPhail, Aamer Ali Shah
AIM: The current study was conducted to investigate the possible role of a compatible solute from radio-halophilic bacterium against desiccation and ultra-violet radiation induced oxidative stress. METHODS AND RESULTS: Nine different radio-resistant bacteria were isolated from desert soil, where strain WMA-LM19 was chosen for detailed studies on the basis of its high tolerance to ultraviolet radiation among all these isolates. 16S rRNA gene sequencing indicated the bacterium was closely related to Stenotrophomonas sp...
May 4, 2018: Journal of Applied Microbiology
https://www.readbyqxmd.com/read/29723354/blocking-or-enhancing-effects-of-some-basic-emollients-in-uva-penetration
#15
Sevgi Akarsu, Emel Fetil, Ozlem Ozbagcivan, Ali Tahsin Gunes
BACKGROUND: Topical agents used in combination with phototherapy or photochemotherapy may have both blocking or enhancing effects in ultraviolet rays. OBJECTIVE: In this in vivo study, the effects of topical petrolatum, basis cream, glycerine, and olive oil on the transmission of ultraviolet A radiation were investigated. METHODS: A test was performed to determine the minimal phototoxic dose on 29 volunteers with only psoralen plus ultraviolet A (PUVA) and then the same test was repeated with white petrolatum, basis cream, glycerine, olive oil, and sunscreen (0...
March 2018: Anais Brasileiros de Dermatologia
https://www.readbyqxmd.com/read/29718444/photobiology-of-vitamins
#16
Mark Lucock, Patrice Jones, Charlotte Martin, Zoe Yates, Martin Veysey, John Furst, Emma Beckett
This review explores contemporary ideas about the relationship between light exposure and vitamin biology. Nutritional biochemistry has long recognized the relationship between vitamins A and D and light exposure, but in recent years other vitamins have also been implicated in photoresponsive biological mechanisms that influence health, well-being, and even evolutionary processes. Interactions between light and vitamins can modify genotype-phenotype relationships across the life cycle, providing a basis for interesting new explanations relevant to wide aspects of human biology...
April 28, 2018: Nutrition Reviews
https://www.readbyqxmd.com/read/29709901/characterization-of-mycosporine-like-amino-acids-in-the-cyanobacterium-nostoc-verrucosum
#17
Kaori Inoue-Sakamoto, Ehsan Nazifi, Chieri Tsuji, Tomoya Asano, Takumi Nishiuchi, Seiichi Matsugo, Kenji Ishihara, Yu Kanesaki, Hirofumi Yoshikawa, Toshio Sakamoto
The aquatic cyanobacterium Nostoc verrucosum forms macroscopic colonies in streams, and its appearance is superficially similar to that of the terrestrial cyanobacterium Nostoc commune. N. verrucosum is sensitive to desiccation, unlike N. commune, although these Nostoc cyanobacterial species share physiological features, including massive extracellular polysaccharide production and trehalose accumulation capability. In this study, water-soluble sunscreen pigments of mycosporine-like amino acids (MAAs) were characterized in N...
April 30, 2018: Journal of General and Applied Microbiology
https://www.readbyqxmd.com/read/29704629/cytotoxicity-of-ceo-2-nanoparticles-using-in-vitro-assay-with-mytilus-galloprovincialis-hemocytes-relevance-of-zeta-potential-shape-and-biocorona-formation
#18
M Sendra, M Volland, T Balbi, R Fabbri, M P Yeste, J M Gatica, L Canesi, J Blasco
Over the last decades, the growth in nanotechnology has provoked an increase in the number of its applications and consumer products that incorporate nanomaterials in their formulation. Metal nanoparticles are released to the marine environment and they can interact with cells by colloids forces establish a nano-bio interface. This interface can be compatible or generate bioadverse effects to cells. The daily use of CeO2 nanoparticles (CeO2 NPs) in industrial catalysis, sunscreen, fuel cells, fuel additives and biomedicine and their potential release into aquatic environments has turned them into a new emerging pollutant of concern...
April 22, 2018: Aquatic Toxicology
https://www.readbyqxmd.com/read/29701240/a-10-year-longitudinal-follow-up-study-of-a-uk-paediatric-transplant-population-to-assess-for-skin-cancer
#19
S H Foo, P G Nightingale, P Gazzani, E Bader, M Ogboli, A Martin-Clavijo, D V Milford, D A Kelly, C Moss, M A Thomson
BACKGROUND: Our earlier study published in 2004 1 found no skin cancer in a cohort of paediatric organ transplant recipients (POTRs) 5 to 16 years post-transplantation. We re-evaluated the same cohort 10 years later. OBJECTIVES: To determine the prevalence of premalignant and malignant skin lesions and identify known risk factors associated with melanocytic naevi in a UK paediatric transplant population. METHODS: Ninety eight POTRs from the original 2004 study were invited to participate in this longitudinal follow-up study...
April 27, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29691848/children-sustain-high-levels-of-skin-dna-photodamage-with-a-modest-increase-of-serum-25-oh-d-3-after-a-summer-holiday-in-northern-europe
#20
J Narbutt, P A Philipsen, A Lesiak, T Sandberg Liljendahl, D Segerbäck, J Heydenreich, D Chlebna-Sokol, P Olsen, G I Harrison, A Pearson, K Baczynska, M Rogowski-Tylman, H C Wulf, A R Young
BACKGROUND: Childhood solar ultraviolet radiation (UVR) exposure increases the risk of skin cancer in adulthood, which is associated with mutations caused by UVR-induced cyclobutane pyrimidine dimers (CPD). Solar UVR is also the main source of vitamin D, essential for healthy bone development in children. OBJECTIVES: The impact of a 12-day Baltic Sea (54o N) beach holiday on serum 25-dihydroxyvitamin D (25(OH)D3 ) and CPD was assessed in 32 healthy Polish children (skin types I-IV)...
April 24, 2018: British Journal of Dermatology
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