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https://www.readbyqxmd.com/read/28444443/-new-approaches-for-the-prevention-of-actinic-keratosis
#1
REVIEW
H Stege, J Krutmann
Actinic keratosis is one of the most common skin diseases. Because of the ongoing demographic changes, it is anticipated that the incidence will further increase. Prevention of actinic keratoses is thus of great importance. By far the most important cause of actinic keratoses is the chronic cumulative irradiation of human skin with ultraviolet B and A radiation from natural sunlight. There is no doubt that use of sunscreens is effective in preventing actinic keratoses. Recent studies indicate that in high-risk groups the regular use of medical devices which are characterized by a very high SPF and which contain liposomally encapsulated DNA repair enzymes are effective in preventing the development of new actinic keratoses even when field cancerization is already present in human skin...
April 25, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28442870/serum-vitamin-d3-levels-and-diffuse-hair-fall-among-the-student-population-in-south-india-a-case-control-study
#2
Kashinath Nayak, Aaina Garg, Prasanna Mithra, Poornima Manjrekar
INTRODUCTION AND AIMS: Hair fall is a common problem faced by many younger people, which has variety of risk factors. Vitamin D3 has emerged as a molecule with key role to play in various disorders. This study was done to assess its role in diffuse hair fall among student population. MATERIALS AND METHODS: This was a case-control study including young adults presenting with complaints of hair fall (>100 a day) as cases, with age-matched healthy controls. Vitamin D3 levels were measured in all the patients...
October 2016: International Journal of Trichology
https://www.readbyqxmd.com/read/28441605/biological-effects-and-medical-applications-of-infrared-radiation
#3
Shang-Ru Tsai, Michael R Hamblin
Infrared (IR) radiation is electromagnetic radiation with wavelengths between 760nm and 100,000nm. Low-level light therapy (LLLT) or photobiomodulation (PBM) therapy generally employs light at red and near-infrared wavelengths (600-100nm) to modulate biological activity. Many factors, conditions, and parameters influence the therapeutic effects of IR, including fluence, irradiance, treatment timing and repetition, pulsing, and wavelength. Increasing evidence suggests that IR can carry out photostimulation and photobiomodulation effects particularly benefiting neural stimulation, wound healing, and cancer treatment...
April 13, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/28437110/ultrafast-transient-absorption-spectroscopy-of-the-sunscreen-constituent-ethylhexyl-triazone
#4
Lewis A Baker, Sarah L Clark, Scott Habershon, Vasilios G Stavros
The ultrafast photoprotection mechanisms in operation of ethylhexyl triazone (EHT, octyl triazone), an approved ultraviolet-B (UV-B) chemical filter for commercial sunscreens, remain elusive, with a notable absence of ultrafast time-resolved measurements. These large organic molecules are of increasing interest as they are suspected to be less likely to penetrate the skin than some of the smaller approved filters, thereby reducing the possible adverse effects from sunscreen products. We apply femtosecond transient absorption spectroscopy with electronic structure calculations to unravel the complete photodeactivation mechanism that EHT undergoes after UV-B irradiation...
April 24, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28432394/-vitamin%C3%A2-d-and-uv-protection
#5
REVIEW
H Stege, T Schwarz
A high percentage of people present with reduced vitamin D3 levels. Reduced vitamin D3 levels have to be supplemented. Oral supplementation can be performed easily and without significant side effects. Because vitamin D3 can be produced in the skin via ultraviolet B (UVB) irradiation, it is possible to elevate reduced vitamin D3 levels by UVB exposure. However, UVB, which is classified as a complete carcinogen, induces skin cancer. Therefore, UVB irradiation should not be utilized to stimulate vitamin D3 synthesis...
April 21, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28414878/do-outdoor-workers-know-their-risk-of-nmsc-perceptions-beliefs-and-preventive-behaviour-among-farmers-roofers-and-gardeners
#6
A Zink, D Wurstbauer, M Rotter, M Wildner, T Biedermann
BACKGROUND: Non-melanoma skin cancer (NMSC) was officially recognized in 2015 as an occupational disease for outdoor workers in Germany. Together with the enormous socioeconomic impact of NMSC, this has led to the continuous demand of evidence-based prevention. However, studies assessing the perceptions and beliefs along with risk behavior of outdoor workers as an essential prerequisite for prevention are rare. OBJECTIVE: To assess perceptions, beliefs, barriers, risk and preventive behavior towards non-melanoma skin cancer among different outdoor groups as a basis for the development of sustainable prevention programs...
April 17, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28403634/potential-use-of-secondary-products-of-the-agri-food-industry-for-topical-formulations-and-comparative-analysis-of-antioxidant-activity-of-grape-leaf-polyphenols
#7
Roger Remy Dresch, Maria Terezinha Kreinecker Dresch, Renata Biegelmeyer, Débora Fretes Argenta, Ricardo Fagundes da Rocha, Helder Ferreira Teixeira, José Cláudio Fonseca Moreira, Amélia Teresinha Henriques
The aim of the present study was to develop a phytocosmetic using Vitis waste by-products, for use as a topical formulation for skin protection against ultraviolet radiation damage. The study also evaluates the free radical scavenger activity of the crude extracts of dried leaves of Vitis vinifera and Vitis labrusca, as well as the anthocyanins, flavonoid fraction and isolated compounds. Next, release and permeation studies of hydrogels were performed using Franz-type diffusion cells. Flavonoid acted more intensively in TRAP and conjugated dienes antioxidant assays, whereas anthocyanins had higher antioxidant activity in hydroxyl and nitric oxide assay...
April 13, 2017: Natural Product Research
https://www.readbyqxmd.com/read/28401272/-sun-protection-factor-50-pro-and-contra
#8
REVIEW
T Herzinger
The use of sunscreens with sun protection factors beyond 50 is controversial. In order to avoid misleading the consumer, several countries have already decided not to declare SPF beyond 50 on sunscreen products. Arguments against high SPF include the following: the risk of imbalanced protection, which could increase the risk of damage caused by longer-wave ultraviolet radiation; imparting a false sense of safety, which could lead to the extension of sun exposure times; health risks from higher concentrations of filter substances; and the only marginally higher blockade provided by high SPF sunscreens...
April 11, 2017: Der Hautarzt; Zeitschrift Für Dermatologie, Venerologie, und Verwandte Gebiete
https://www.readbyqxmd.com/read/28399499/occurrence-of-personal-care-products-as-emerging-chemicals-of-concern-in-water-resources-a-review
#9
REVIEW
Diana Montes-Grajales, Mary Fennix-Agudelo, Wendy Miranda-Castro
Personal care products (PCPs) are a diverse group of common household substances used for health, beauty and cleaning purposes. These include disinfectants, fragrances, insect repellents, preservatives and UV filters, among others. Some of them are considered chemicals of emerging concern due to their presence and negative impact on aquatic ecosystems, specially related to endocrine disruption and reproductive disorders. The entry of those chemicals to water bodies occurs mainly through the sewage effluents from wastewater treatment plants due to their incomplete or inefficient removal...
April 8, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28398241/investigating-the-origins-of-toxic-response-in-tio%C3%A2-nanoparticle-treated-cells
#10
Gamze Kuku, Mustafa Culha
Titanium dioxide nanoparticles (TiO₂ NPs) are widely used in sunscreens, cosmetics and body implants, and this raises toxicity concerns. Although a large number of reports claim that they are safe to use, others claim that they induce reactive oxygen species formation and can be carcinogenic. In this study, the origins of toxic response to TiO₂ NPs were investigated by using Surface-enhanced Raman spectroscopy (SERS) which provides multidimensional information on the cellular dynamics at single cell level without any requirement for cell fixation...
April 11, 2017: Nanomaterials
https://www.readbyqxmd.com/read/28392645/knowledge-and-behavior-regarding-cosmetics-in-koreans-visiting-dermatology-clinics
#11
Soyun Cho, Sohee Oh, Nack In Kim, Young Suck Ro, Joung Soo Kim, Young Min Park, Chun Wook Park, Weon Ju Lee, Dong Kun Kim, Dong Won Lee, Sang Jun Lee
BACKGROUND: Cosmetics can affect the skin condition profoundly, and yet no survey has been performed in Koreans visiting dermatology clinics. OBJECTIVE: To assess knowledge and consumer behavior regarding cosmetics in Koreans visiting dermatology clinics. METHODS: A questionnaire consisting of 43 questions concerning demographics and use/knowledge/selection/purchase of cosmetics was given to patients and accompanying persons who visited dermatologic clinics in university and private clinic settings...
April 2017: Annals of Dermatology
https://www.readbyqxmd.com/read/28391983/-the-role-of-sunscreens-in-fibrosing-frontal-alopecia
#12
J-L Schmutz
No abstract text is available yet for this article.
April 6, 2017: Annales de Dermatologie et de Vénéréologie
https://www.readbyqxmd.com/read/28391487/ecotoxicological-evaluation-of-the-uv-filters-ethylhexyl-dimethyl-p-aminobenzoic-acid-and-octocrylene-using-marine-organisms-isochrysis-galbana-mytilus-galloprovincialis-and-paracentrotus-lividus
#13
A Giraldo, R Montes, R Rodil, J B Quintana, L Vidal-Liñán, R Beiras
The growing concern regarding the negative effects of solar radiation on the skin has led to a drastic increase in the use of sunscreens containing in its composition up to 10% of aromatic chemicals, such as ethylhexyl dimethyl p-aminobenzoic acid (OD-PABA) and octocrylene (OC). The objective of this study was to evaluate the toxicity and to assess the environmental risk posed by these two ultraviolet filters, widely used in cosmetics and as plastic additives, in the marine environment. Several ecotoxicological bioassays were performed with three model organisms belonging to different trophic levels: the microalgae Isochrysis galbana, the mussel Mytilus galloprovincialis, and the sea urchin Paracentrotus lividus...
April 8, 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28388481/membrane-lipid-profiles-of-coral-responded-to-zinc-oxide-nanoparticle-induced-perturbations-on-the-cellular-membrane
#14
Chuan-Ho Tang, Ching-Yu Lin, Shu-Hui Lee, Wei-Hsien Wang
Zinc oxide nanoparticles (nZnOs) released from popular sunscreens used during marine recreation apparently endanger corals; however, the known biological effects are very limited. Membrane lipids constitute the basic structural element to create cell a dynamic structure according to the circumstance. Nano-specific effects have been shown to mechanically perturb the physical state of the lipid membrane, and the cells accommodating the actions of nZnOs can be involved in the alteration of the membrane lipid composition...
March 31, 2017: Aquatic Toxicology
https://www.readbyqxmd.com/read/28358282/efficacy-of-a-film-forming-medical-device-containing-sunscreen-50-and-piroxicam-0-8-in-actinic-keratosis-and-field-cancerization-a-multicenter-assessor-blinded-3-month-trial
#15
Mario Puviani, Chiara Galloni, Silvia Marchetti, Paolo Sergio Pavone, Silvia Lovati, Giuseppe Pistone, Valentina Caputo, Giovanna Tilotta, Giuseppe Scarcella, Elena Campione, Laura Diluvio, Virginia Garofalo, Luca Bianchi, Massimo Milani
INTRODUCTION: Sunscreen protection in subjects with actinic keratosis (AK) is highly recommended to prevent clinical evolution of this in situ skin cancer condition. Use of topical anti-cyclooxygenase drugs such as diclofenac and piroxicam reduces the number of lesions and improves the cancerization field. A film-forming medical device in a cream formulation containing organic and inorganic sun-filters (50+ SPF) and piroxicam 0.8% (ACTX) has shown in a pilot, single-center, open trial to reduce AK lesions improving the cancerization field...
April 20, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/28351139/occurrence-distribution-and-fate-of-organic-uv-filters-in-coral-communities
#16
Mirabelle M P Tsui, James C W Lam, T Y Ng, P O Ang, Margaret B Murphy, Paul K S Lam
Organic ultraviolet (UV) filters are widely used in personal care products and occur ubiquitously in the aquatic environment. In this study, concentrations of seven commonly used organic UV filters were determined in seawater, sediment and five coral species collected from the eastern Pearl River Estuary of South China Sea. Five compounds, benzophenone-1, -3, and -8 (BP-1, -3, and -8), octocrylene (OC) and octyl dimethyl-p-aminobenzoic acid (ODPABA), were detected in the coral tissues with the highest detection frequencies (>65%) and concentrations (31...
April 10, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28343227/what-is-the-key-to-improving-renal-transplant-recipients-awareness-of-skin-cancer-risk
#17
Alessandro Borghi, Monica Corazza, Yuri Battaglia, Elisa Maietti, Sara Minghetti, Annarosa Virgili
BACKGROUND: Previous studies have shown poor compliance rates regarding sun protection among organ transplant recipients. OBJECTIVE: The main objective of the present study was to assess the awareness among renal transplant recipients (RTRs) of their risk of non-melanoma skin cancer (NMSC) development and their sunscreen use. The influence of several potentially relevant variables was also assessed in order to identify possible weak points on which to concentrate efforts in this respect...
March 25, 2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/28343007/bioconcentration-and-multi-biomarkers-of-organic-uv-filters-bm-dbm-and-od-paba-in-crucian-carp
#18
Binni Ma, Guanghua Lu, Jianchao Liu, Zhenhua Yan, Haohan Yang, Ting Pan
Organic UV filters (OUV-Fs) are increasingly used in sunscreens and personal care products. In the present work, the bioconcentration and multi-biomarker effects of butyl methoxydibenzoylmethane (BM-DBM) and ethylhexyl dimethyl p-aminobenzoate (OD-PABA) were investigated in crucian carp (Carassius auratus). The fish were exposed to various concentrations of BM-DBM (3.88, 35.61, 181.85 and 337.15μg/L), OD-PABA (4.66, 53.83, 264.22 and 459.32μg/L) and their mixture (2.31+2.79, 23.69+26.18, 97.37+134.81 and 193...
March 23, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28341613/radical-scavenging-activity-of-a-sunscreen-enriched-by-antioxidants-providing-protection-in-the-whole-solar-spectral-range
#19
Carla Souza, Patrícia Maia Campos, Sabine Schanzer, Stephanie Albrecht, Silke B Lohan, Juergen Lademann, Maxim E Darvin, Martina C Meinke
The literature claims that incorporation of antioxidants into sunscreens provides additional skin photoprotection by scavenging free radicals formed due to sun radiation, but there are limited in vivo studies that support this hypothesis. This study aims to examine whether addition of antioxidants to a broad-spectrum sunscreen increases its photoprotective effect in real-use conditions. Sunscreen formulations composed of stable UV filters (Tinosorb® S, Tinosorb® M, Uvinul® APlus, and Uvinul® T150) alone or in combination with antioxidants (Spirulina and dimethylmethoxy chromanol-loaded solid lipid nanoparticles) were developed and their appearance, odor, rheological behavior, Sun Protection Factor (SPF), and UVA protection were analyzed...
March 21, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28332195/skin-cancer-history-sun-related-attitudes-behaviour-and-sunburn-among-renal-transplant-recipients-versus-general-population
#20
Vivian Ka Ying Leung, Suzanne Jane Dobbinson, David Josef Goodman, John Kanellis, Alvin Heong Chong
BACKGROUND/OBJECTIVES: Renal transplant recipients (RTR) have both an excessive skin cancer incidence and a high mortality rate. In Australia RTR receive extensive public education on skin cancer and many undergo further education pre/post-transplant. This study examines whether RTR have sufficiently rigorous sun protection behaviour compared with the general population. METHODS: Altogether 179 RTR from two large Melbourne hospitals involving skin clinic teams in patient care were recruited to undergo cross-sectional telephone interviews...
March 23, 2017: Australasian Journal of Dermatology
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