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climacteric syndrome

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https://www.readbyqxmd.com/read/28593720/phytoestrogen-rich-natural-preparation-for-treatment-of-climacteric-syndrome-and-atherosclerosis-prevention-in-perimenopausal-women
#1
RANDOMIZED CONTROLLED TRIAL
T V Kirichenko, V A Myasoedova, V A Orekhova, A L Ravani, N A Nikitina, A V Grechko, I A Sobenin, A N Orekhov
The present study evaluated the risks and benefits of phytoestrogen treatment in healthy perimenopausal women in relation to the dynamics of climacteric syndrome and progression of atherosclerosis. Study participants were treated with placebo or phytoestrogen-rich natural preparation Karinat based on grape (Vitis vinifera) seeds, green tea (Camellia sinensis) leaves, hop (Hunulus lupulus) cone powder and garlic (Allium sativum) powder. The dynamics of climacteric syndrome was evaluated by Kupperman Index and Utian Quality of Life Scale...
August 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28588485/beneficial-effects-and-toxicity-studies-of-xian-ling-gu-bao-on-bone-metabolism-in-ovariectomized-rats
#2
Hao Wu, Qingxiang Zhong, Jing Wang, Man Wang, Fang Fang, Zhi Xia, Rongling Zhong, Houcai Huang, Zhongcheng Ke, Yingjie Wei, Liang Feng, Ziqi Shi, E Sun, Jie Song, Xiaobin Jia
Xian-ling-gu-bao (XLGB) is a well-known patented traditional Chinese prescription widely used to treat osteoporosis, osteoarthritis, aseptic bone necrosis, or climacteric syndrome. However, recent reports have suggested that XLGB may cause liver injury in humans. In the present study, we aimed to evaluate the efficacy of XLGB in the prevention of osteoporosis in the zebrafish and ovariectomized (OVX) rats, both of which have been used as osteoporosis models. The safety of XLGB after long-term administration to OVX rats was also assessed...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28574385/-connective-tissue-metabolic-features-in-climacteric-syndrome-s-patients-with-various-types-of-menopause
#3
O Gryshchenko, I Vasylieva, K Gryshchuk
The purpose of the study was investigation of the connective tissue metabolic features among women with menopausal syndrome (MS) and MS, in which the arthropathic syndrome is leading and comparative analysis of the connective tissue indicators exchange during menopause caused in a surgical and natural way. We examined 70 women in total, menopause duration they accounted for 1,95±1,1 years, it came both as natural, and as a result of a surgery. The main group included 40 women with MS with leading arthropathic syndrome...
April 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28392498/magnesium-in-the-gynecological-practice-a-literature-review
#4
REVIEW
Fabio Parazzini, Mirella Di Martino, Paolo Pellegrino
A growing amount of evidence suggests that magnesium deficiency may play an important role in several clinical conditions concerning women health such as premenstrual syndrome, dysmenorrhea, and postmenopausal symptoms. A number of studies highlighted a positive correlation between magnesium administration and relief or prevention of these symptoms, thus suggesting that magnesium supplementation may represent a viable treatment for these conditions. Despite this amount of evidence describing the efficacy of magnesium, few and un-systematize data are available about the pharmacological mechanism of this ion for these conditions...
February 1, 2017: Magnesium Research: Official Organ of the International Society for the Development of Research on Magnesium
https://www.readbyqxmd.com/read/28327172/effect-of-guizhifulingwan-keishibukuryogan-on-climacteric-syndrome-study-protocol-for-a-randomized-controlled-pilot-trial
#5
Jung-Eun Kim, Junghyo Cho, Ojin Kwon, Ae-Ran Kim, Hyo-Ju Park, So-Young Jung, Joo-Hee Kim, Mikyung Kim, Hye-Yoon Lee, Jun-Hwan Lee
BACKGROUND: The aim of this study is to explore the efficacy of Guizhifulingwan (GFW) in the treatment of climacteric syndrome in women. METHODS/DESIGN: This is a single-center, randomized, placebo-controlled, parallel-group design pilot trial. Fifty participants with climacteric syndrome will be randomly allocated to the GFW or placebo group in a 1:1 ratio. The participants will be administered GFW or placebo granules three times a day for 4 weeks and will be followed up for a further 4 weeks...
March 21, 2017: Trials
https://www.readbyqxmd.com/read/28288692/does-cimicifuga-racemosa-have-the-effects-like-estrogen-on-the-sublingual-gland-in-ovariectomized-rats
#6
Yun-Meng Da, Kai-Yu Niu, Shu-Ya Liu, Ke Wang, Wen-Juan Wang, Jing Jia, Li-Hua Qin, Wen-Pei Bai
BACKGROUND: Cimicifuga racemosa is one of the herbs used for the treatment of climacteric syndrome, and it has been cited as an alternative therapy to estrogen. Apart from hectic fevers, dyspareunia and so on, dry mouth also increase significantly after menopause. It has not yet been reported whether C. racemosa has any impact on the sublingual gland, which may relate to dry mouth. In an attempt to determine this, we have compared the effects of estrogen and C. racemosa on the sublingual gland of ovariectomized rats...
March 14, 2017: Biological Research
https://www.readbyqxmd.com/read/28284656/metabolic-syndrome-in-hiv-infected-middle-aged-women-on-antiretroviral-therapy-prevalence-and-associated-factors
#7
Lívia D Akl, Ana L R Valadares, Monica Jacques de Moraes, Aarão M Pinto-Neto, Bianca Lagrutta, Lúcia Costa-Paiva
OBJECTIVES: To determine the prevalence of metabolic syndrome (MetS) and its associated factors in a group of HIV-infected middle-aged women. METHODS: Cross-sectional study including 273 HIV-infected climacteric women of 40-60 years of age under care in two HIV outpatient reference centers in Brazil. Metabolic syndrome diagnosis was based on 2006 International Diabetes Federation criteria. Sociodemographic, clinical and behavioral factors were evaluated as well as HIV infection-related parameters...
May 2017: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28252428/-risk-fsctors-of-cardiovascular-disease-in-patients-with-rosacea
#8
Ts Tsiskarishvili, A Katsitadze, N I Tsiskarishvili, V Chigladze
The purpose of the research was to study the lipid profile, some indices of hemostasis and cytokine status of rosacea patients with severe climacteric syndrome. Serum lipid profile was studied by means of the following parameters: total cholesterol, high density lipoproteins (HDL), low density lipoproteins (LDL), triglycerides (the study of lipid profile was performed by the device "INTEGRAM +400" (Company "ROSH»). Haemostatic system was evaluated in terms of prothrombin, thrombin time. Content of fibrinogen, fibrinolytic activity, and prothrombin index were determined...
January 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28225859/prevalence-of-metabolic-syndrome-in-pre-and-postmenopausal-women
#9
Ricardo de Marchi, Cátia Millene Dell'Agnolo, Tiara Cristina Romeiro Lopes, Angela Andréia França Gravena, Marcela de Oliveira Demitto, Sheila Cristina Rocha Brischiliari, Deise Helena Pelloso Borghesan, Maria Dalva de Barros Carvalho, Sandra Marisa Pelloso
Objective: The objective of this study was to determine the prevalence of metabolic syndrome (MS) and its components among pre- and postmenopausal women, as well as the association between menopausal status and MS. Materials and methods: A retrospective study was conducted at a reference cardiology outpatient clinic in a city located in Northwestern Paraná State, Brazil. A total of 958 medical records of symptomatic climacteric women evaluated between 2010 and 2014 were analyzed...
March 2017: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27982200/metabolic-syndrome-and-sexual-function-in-postmenopausal-women
#10
Kathiussa Dombek, Emille Joana Medeiros Capistrano, Ana Carolina Carioca Costa, Lizanka Paola Figueiredo Marinheiro
Objective: The purpose of this study was to evaluate whether female sexual dysfunction (FSD) is associated with metabolic syndrome (MS) and to identify factors that contribute to FSD in postmenopausal women. Subjects and methods: This was a cross-sectional study in 111 sexually active women aged 45-65 years. We applied the Female Sexual Function Index (FSFI) to evaluate the participant's sexual function and a structured questionnaire to collect demographic, socioeconomic, clinical, anthropometric, and laboratory data...
November 2016: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27900987/effect-of-half-dose-and-standard-dose-conjugated-equine-estrogens-combined-with-natural-progesterone-or-dydrogesterone-on-components-of-metabolic-syndrome-in-healthy-postmenopausal-women-a-randomized-controlled-trial
#11
RANDOMIZED CONTROLLED TRIAL
Wei Xue, Yan Deng, Yan-Fang Wang, Ai-Jun Sun
BACKGROUND: Menopausal hormone therapy (MHT) has been proven to have beneficial effects on several components of metabolic syndrome. However, the effects vary according to different regimens, dosages, and duration of MHT. The aim of the study was to evaluate the effect of standard-dose 0.625 mg conjugated equine estrogen (CEE) and half-dose 0.3 mg CEE daily with different progestogens in a continuous sequential regimen on postmenopausal metabolic parameters in generally healthy postmenopausal women...
December 5, 2016: Chinese Medical Journal
https://www.readbyqxmd.com/read/27416682/-phytosaponins-of-dioscorea-prospects-for-application-in-women
#12
REVIEW
Yu O Fedotoval, A G Shleikin
This literature review is focused on findings concerning the pharmacological effects of Dioscorea phytosaponins (DPSs) on female organism. Expediency and prospects of developing DPS preparations for the treatment of mnestic and metabolic disorders accompanying climacteric syndrome are assessed.
2016: Eksperimental'naia i Klinicheskaia Farmakologiia
https://www.readbyqxmd.com/read/27343311/efficacy-of-femarelle-for-the-treatment-of-climacteric-syndrome-in-postmenopausal-women-an-open-label-trial
#13
MULTICENTER STUDY
Fang-Ping Chen, Chee Jen Chang, An-Shine Chao, Hong-Yuan Huang, Jian-Pei Huang, Meng-Hsing Wu, Ching-Chou Tsai, Fu-Tsai Kung, Ching-Wen Chang, Yung-Chieh Tsai
OBJECTIVE: To assess the effects of 2 months of treatment with Femarelle for climacteric syndrome in Taiwanese postmenopausal women. MATERIALS AND METHODS: A multi-center, open-label trial of 260 postmenopausal women, age ≥ 45 years with vasomotor symptoms. Women were enrolled after obtaining a detailed medical history and a thorough physical examination. They then received Femarelle (640 mg/d) twice daily for 8 weeks. The primary outcome was the changes in the frequency and severity of hot flushes from baseline to 4 weeks (1 month) and 8 weeks (2 months)...
June 2016: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27261993/hatha-yoga-practice-decreases-menopause-symptoms-and-improves-quality-of-life-a-randomized-controlled-trial
#14
RANDOMIZED CONTROLLED TRIAL
Márcia P Jorge, Danilo F Santaella, Isabella M O Pontes, Victor K M Shiramizu, Ezequiel B Nascimento, Alícia Cabral, Telma M A M Lemos, Regina H Silva, Alessandra M Ribeiro
OBJECTIVES: Yoga practice includes a group of specific psychophysical techniques. Although previous studies showed beneficial effects of yoga for health and rehabilitation, improving quality of life, there are few studies on the possible therapeutic application of yoga during the climacteric period. The purpose of this study was to investigate the psychophysiological effects of Hatha Yoga regular practice in post-menopausal women. METHODS: Eighty-eight post-menopausal women volunteered for this 12-week trial...
June 2016: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/27222316/yifuning-postpones-ovarian-aging-through-antioxidant-mechanisms-and-suppression-of-the-rb-p53-signal-transduction-pathway
#15
Lei Liang, Xu-Hui Zhang, Bo Ji, Hui Yao, Xiao-Mei Ling, Zhi-Jian Guo, Hong-Zhu Deng, Xin-Rong Wu
Yifuning is a traditional Chinese medicine recipe that has been used for many years in China for its effects on treating climacteric syndrome in women. The present study aimed to demonstrate the effects and underlying molecular mechanism of Yifuning on the ovaries of aging rats. Selected aging rats were administered different doses of Yifuning (1.0 or 2.0 g/kg by lavage), and after 6 weeks the rats were sacrificed. The activit of indicators of oxidative stress in the serum were measured. The expression levels of 8-oxo-2'-deoxyguanosine (8-OHDG) and p53 in the ovaries were examined using immunohistochemistry...
July 2016: Molecular Medicine Reports
https://www.readbyqxmd.com/read/27219836/a-cross-cultural-comparison-of-climacteric-symptoms-self-esteem-and-perceived-social-support-between-mosuo-women-and-han-chinese-women
#16
Ying Zhang, Xudong Zhao, Rainer Leonhart, Maya Nadig, Annette Hasenburg, Michael Wirsching, Kurt Fritzsche
OBJECTIVE: This cross-cultural study aimed to compare climacteric symptoms, self-esteem, and perceived social support between Mosuo and Han Chinese women, and to explore the interaction between culture and climacteric symptoms. Mosuo is a Chinese minority group with a matriarchal structure, and Han Chinese is the majority ethnic group in China with a patriarchal structure. METHODS: Through convenience sampling, 54 Mosuo women and 52 Han Chinese women between 40 and 60 years of age completed the sociodemographic questionnaire, the Menopause Rating Scale, the Self-Esteem Scale, and the Perceived Social Support Scale...
July 2016: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27091671/premature-ovarian-insufficiency-the-context-of-long-term-effects
#17
REVIEW
A Podfigurna-Stopa, A Czyzyk, M Grymowicz, R Smolarczyk, K Katulski, K Czajkowski, B Meczekalski
PURPOSE: Premature ovarian insufficiency (POI) is defined as the cessation of the ovarian function before the age of 40 years. POI aetiology may be related to iatrogenic or endogenous factors and in many cases remains unclear. The aim of this review was to characterize the long-term consequences of POI. METHODS: The available literature regarding the long-term consequences of POI from MEDLINE has been reviewed. RESULTS: Lack of ovarian steroids synthesis has serious consequences for women's health...
September 2016: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/27040419/traditional-chinese-medicine-valuably-augments-therapeutic-options-in-the-treatment-of-climacteric-syndrome
#18
REVIEW
Sarah Eisenhardt, Johannes Fleckenstein
Climacteric syndrome refers to recurring symptoms such as hot flashes, chills, headache, irritability and depression. This is usually experienced by menopausal women and can be related to a hormonal reorganization in the hypothalamic-pituitary-gonadal axis. In Traditional Chinese Medicine, originating 1000s of years ago, above-mentioned symptoms can be interpreted on the basis of the philosophic diagnostic concepts, such as the imbalance of Yin and Yang, the Zang-Fu and Basic substances (e.g. Qi, Blood and Essence)...
July 2016: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/27022113/acupuncture-as-an-integrative-approach-for-the-treatment-of-hot-flashes-in-women-with-breast-cancer-a-prospective-multicenter-randomized-controlled-trial-acclimat
#19
RANDOMIZED CONTROLLED TRIAL
Grazia Lesi, Giorgia Razzini, Muriel Assunta Musti, Elisa Stivanello, Chiara Petrucci, Benedetta Benedetti, Ermanno Rondini, Maria Bernadette Ligabue, Laura Scaltriti, Alberto Botti, Fabrizio Artioli, Pamela Mancuso, Francesco Cardini, Paolo Pandolfi
PURPOSE: To determine the effectiveness of acupuncture for the management of hot flashes in women with breast cancer. PATIENTS AND METHODS: We conducted a pragmatic, randomized controlled trial comparing acupuncture plus enhanced self-care versus enhanced self-care alone. A total of 190 women with breast cancer were randomly assigned. Random assignment was performed with stratification for hormonal therapy; the allocation ratio was 1:1. Both groups received a booklet with information about climacteric syndrome and its management to be followed for at least 12 weeks...
May 20, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/26913040/coupling-of-physiological-and-proteomic-analysis-to-understand-the-ethylene-and-chilling-induced-kiwifruit-ripening-syndrome
#20
Ioannis S Minas, Georgia Tanou, Evangelos Karagiannis, Maya Belghazi, Athanassios Molassiotis
Kiwifruit [Actinidia deliciosa (A. Chev.) C.F. Liang et A.R. Ferguson, cv. "Hayward"] is classified as climacteric fruit and the initiation of endogenous ethylene production following harvest is induced by exogenous ethylene or chilling exposure. To understand the biological basis of this "dilemma," kiwifruit ripening responses were characterized at 20°C following treatments with exogenous ethylene (100 μL L(-1), 20°C, 24 h) or/and chilling temperature (0°C, 10 days). All treatments elicited kiwifruit ripening and induced softening and endogenous ethylene biosynthesis, as determined by 1-aminocyclopropane-1-carboxylic acid (ACC) content and ACC synthase (ACS) and ACC oxidase (ACO) enzyme activities after 10 days of ripening at 20°C...
2016: Frontiers in Plant Science
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