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https://www.readbyqxmd.com/read/28446018/development-of-personalized-urination-recognition-technology-using-smart-bands
#1
Sung-Jong Eun, Taeg-Keun Whangbo, Dong Kyun Park, Khae-Hawn Kim
PURPOSE: This study collected and analyzed activity data sensed through smart bands worn by patients in order to resolve the clinical issues posed by using voiding charts. By developing a smart band-based algorithm for recognizing urination activity in patients, this study aimed to explore the feasibility of urination monitoring systems. METHODS: This study aimed to develop an algorithm that recognizes urination based on a patient's posture and changes in posture...
April 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28446013/the-in-vivo-effect-of-ytterbium-doped-fiber-laser-on-rat-buccal-mucosa-as-a-simulation-of-its-effect-on-the-urinary-tract-a-preclinical-histopathological-evaluation
#2
Songzhe Piao, Yue Wang, Young Ju Lee, Seungsoo Hong, Yoonchan Jeong, Seung-June Oh
PURPOSE: The aim of this study was to perform a histological analysis of the effect of a ytterbium-doped fiber (YDF) laser on oral buccal mucosa tissue in vivo to simulate its effect on the mucosa of the lower urinary tract. METHODS: A total of 90 8-week-old Sprague-Dawley rats were anesthetized with urethrane (1.2 g/kg intraperitoneally). A prespecified inner buccal mucosal site was irradiated with a YDF master-oscillator power amplifier (MOPA) system for 60 seconds, with output power settings of 0...
April 2017: International Neurourology Journal
https://www.readbyqxmd.com/read/28445999/crystal-orientation-effect-on-the-subsurface-deformation-of-monocrystalline-germanium-in-nanometric-cutting
#3
Min Lai, Xiaodong Zhang, Fengzhou Fang
Molecular dynamics simulations of nanometric cutting on monocrystalline germanium are conducted to investigate the subsurface deformation during and after nanometric cutting. The continuous random network model of amorphous germanium is established by molecular dynamics simulation, and its characteristic parameters are extracted to compare with those of the machined deformed layer. The coordination number distribution and radial distribution function (RDF) show that the machined surface presents the similar amorphous state...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28445998/infrared-raman-and-magnetic-resonance-spectroscopic-study-of-sio2-c-nanopowders
#4
Dariya Savchenko, Vladimir Vorliček, Ekaterina Kalabukhova, Aleksandr Sitnikov, Andrii Vasin, Dmytro Kysil, Stanislav Sevostianov, Valentyn Tertykh, Alexei Nazarov
Optical and magnetic properties of SiO2:C nanopowders obtained by chemical and thermal modification of fumed silica were studied by Fourier transform infrared spectroscopy, Raman, continuous wave (CW) electron paramagnetic resonance (EPR), echo-detected EPR and pulsed electron nuclear double resonance (ENDOR) spectroscopy. Two overlapping signals of Lorentzian lineshape were detected in CW EPR spectra of the initial SiO2:C. The EPR signal at g = 2.0055(3) is due to the silicon dangling bonds, which vanishes after thermal annealing, and the second EPR signal at g = 2...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28445996/energy-transfer-in-ce0-85tb0-15f3-nanoparticles-ctab-shell-chlorin-e6-system
#5
Mykhaylo Yu Losytskyy, Liliia V Kuzmenko, Oleksandr B Shcherbakov, Nikolai F Gamaleia, Andrii I Marynin, Valeriy M Yashchuk
Formation and electronic excitation energy transfer process in the nanosystem consisting of Ce0.85Tb0.15F3 nanoparticles, cetrimonium bromide (CTAB) surfactant, and chlorin e6 photosensitizer were studied. It was shown that chlorin e6 molecules bind to Ce0.85Tb0.15F3 NP in the presence of CTAB forming thus Ce0.85Tb0.15F3 NP-CTAB-chlorin e6 nanosystem. We consider that binding occurs via chlorin e6 embedding in the shell of CTAB molecules, formed around NP. In the Ce0.85Tb0.15F3 NP-CTAB-chlorin e6 nanosystem, electronic excitation energy transfer from Ce(3+) to chlorin e6 takes place both directly (with the 0...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28445964/abo-blood-group-and-ovarian-reserve-a-meta-analysis-and-systematic-review
#6
Jie Deng, Mengmeng Jia, Xiaolin Cheng, Zhen Yan, Dongmei Fan, Xiaoyu Tian
Ovarian reserve reflects a woman's fertility potential. The ABO blood group system is a very stable genetic marker. Although many recent studies have explored the relationship between ABO blood group and ovarian reserve, a consensus has not yet been reached. This paper is the first meta-analysis and systematic review of the relationship between ABO blood type and ovarian reserve. We analyzed seven cross-sectional studies evaluating follicle stimulating hormone (FSH) or anti-Mullerian hormone (AMH) levels in 55,113 participants to determine ovarian reserve...
April 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28445963/genetic-polymorphisms-of-bcl-2-promoter-in-cancer-susceptibility-and-prognosis-a-meta-analysis
#7
Zhongqiang Yao, Binhui Yang, Zhongqiu Liu, Wei Li, Qihua He, Xingchun Peng
Bcl-2 is critical for tumorigenesis. However, previous studies on the association of Bcl-2 promoter polymorphisms with predisposition to different cancer types are somewhat contradictory. Therefore, we performed this meta-analysis regarding the relationship between Bcl-2 promoter single nucleotide polymorphisms (SNPs) and cancer susceptibility and prognosis. Up to August 2016, 32 original publications were identified covering two Bcl-2 promoter SNPs (rs2279115 and rs1801018). Our results showed statistically significant association between rs2279115 and cancer susceptibility and prognosis in all four genetic models but not in rs1801018...
April 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28445957/peripheral-kynurenine-tryptophan-ratio-is-not-a-reliable-marker-of-systemic-indoleamine-2-3-dioxygenase-a-lesson-drawn-from-patients-on-hemodialysis
#8
Yuanhan Chen, Zhen Xie, Chenggen Xiao, Min Zhang, Zhilian Li, Jianteng Xie, Yusheng Zhang, Xingchen Zhao, Pengfei Zeng, Liyi Mo, Xinling Liang, Wei Shi
Indoleamine 2,3-dioxygenase (IDO) has emerged as a pivotal enzyme for mediating immune tolerance. Because IDO metabolizes tryptophan into kynurenine, the plasma kynurenine/tryptophan (Kyn/Trp) ratio has been widely used as a marker of systemic IDO. Here, we evaluated the clinical value of using the plasma Kyn/Trp ratio to estimate cell-mediated immune responses to tuberculin skin testing and risk of new bacterial infection. We also compared the Kyn/Trp ratio to a novel IDO marker, the IDO median fluorescence index (MFI) of peripheral blood mononuclear cells, which was determined by flow cytometry...
April 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28445944/angiotensin-converting-enzyme-2-overexpression-protects-against-doxorubicin-induced-cardiomyopathy-by-multiple-mechanisms-in-rats
#9
Hui Ma, Jing Kong, Yu-Lin Wang, Jun-Long Li, Nai-Hao Hei, Xin-Ran Cao, Jing-Jing Yang, Wen-Jiang Yan, Wen-Jing Liang, Hong-Yan Dai, Bo Dong
Angiotensin-converting enzyme 2 (ACE2) is considered a potential therapeutic target of the renin-angiotensin system (RAS) for the treatment of cardiovascular diseases. We aimed to explore the effects of ACE2 overexpression on doxorubicin-induced cardiomyopathy in rats. Rats were randomly divided into treatment and control groups. The rats of treatment group were injected intraperitoneally with 6 doses of doxorubicin (2.5 mg/kg) within a period of two weeks. Two weeks after the initial injection of doxorubicin, these rats were randomly divided into Mock, Ad-EGFP, Ad-ACE2, and Cilazapril groups...
April 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28445921/assessment-of-the-synergic-effect-of-immunomodulation-on-nerve-repair-using-multi-parametric-mr-imaging
#10
Chu-Shan Zheng, Xiang Zhang, Yue-Yao Chen, Fang Zhang, Xiao-Hui Duan, Mei-Wei Chen, Lie-Jing Lu, Jun Shen
Introduction:The immune system plays a pivotal role in nerve injury. The aim of this study was to investigate the role of multi-parametric magnetic resonance (MR) imaging in the evaluation of the synergic effect of immunomodulation on nerve regeneration in neurotmesis. METHODS: Rats with sciatic nerve neurotmesis and surgical repair underwent serial multi-parametric MR examinations over an 8 week period after subepineurial microinjection of lipopolysaccharide (LPS) and subsequent subcutaneous injection of FK506 or subepineurial microinjection of LPS or phosphate buffered saline (PBS) alone...
April 26, 2017: Muscle & Nerve
https://www.readbyqxmd.com/read/28445907/-acceptance-of-emotion-sensitive-training-systems-of-individuals-suffering-from-facial-paralysis-and-their-relatives
#11
Uwe Altmann, Susanne Worrack, Magdalena C Kaczmarek, Julia Mühleck, Gerd Fabian Volk, Orlando Guntinas-Lichius, Bernhard M Strauß
No abstract text is available yet for this article.
April 26, 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28445888/differential-effects-of-inflammatory-and-psychosocial-stress-on-mood-hypothalamic-pituitary-adrenal-axis-and-inflammation-in-remitted-depression
#12
Peter Niemegeers, Peter De Boer, Glenn J H Dumont, Filip Van Den Eede, Erik Fransen, Stephan J Claes, Manuel Morrens, Bernard G C Sabbe
BACKGROUND/AIMS: Major depressive disorder (MDD) is highly recurrent. This may be due to increased stress sensitivity after remission. Both inflammatory and psychosocial stressors are implicated in the pathogenesis of MDD, but the additive or differential effect is unclear. METHODS: We conducted a single-blind placebo-controlled study to investigate the effects of inflammatory stress (i.e., typhoid vaccination), psychosocial stress (i.e., Trier Social Stress Test [TSST]), or a combination of both in women (25-45 years old) with (partially) remitted recurrent MDD (n = 21) and healthy female controls (n = 18)...
April 27, 2017: Neuropsychobiology
https://www.readbyqxmd.com/read/28445887/use-of-phosphorus-binders-among-non-dialysis-chronic-kidney-disease-patients-and-mortality-outcomes
#13
Simran K Bhandari, In-Lu A Liu, Dean A Kujubu, Trung Huynh, Hind Behayaa, Csaba P Kovesdy, Kamyar Kalantar-Zadeh, Steven J Jacobsen, John J Sim
BACKGROUND: Whether the benefits of phosphorus binders extend to those without end stage renal disease is uncertain. Among a large diverse non-dialysis chronic kidney disease (CKD) population with hyperphosphatemia, we sought to evaluate phosphorus binder use and compare mortality risk between patients prescribed and not prescribed binders. METHODS: A retrospective cohort study within an integrated health system (January 1, 1998 - December 31, 2012) among CKD patients (age ≥18) was performed...
April 27, 2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28445884/synergistic-action-of-presynaptic-muscarinic-acetylcholine-receptors-and-adenosine-receptors-in-developmental-axonal-competition-at-the-neuromuscular-junction
#14
Laura Nadal, Neus Garcia, Erica Hurtado, Anna Simó, Marta Tomàs, Maria Angel Lanuza, Victor Cilleros, Josep Maria Tomàs
The development of the nervous system involves the initial overproduction of synapses, which promotes connectivity. Hebbian competition between axons with different activities leads to the loss of roughly half of the overproduced elements and this refines connectivity. We used quantitative immunohistochemistry to investigate, in the postnatal day 7 (P7) to P9 neuromuscular junctions, the involvement of muscarinic receptors (muscarinic acetylcholine autoreceptors and the M1, M2, and M4 subtypes) and adenosine receptors (A1 and A2A subtypes) in the control of axonal elimination after the mouse levator auris longus muscle had been exposed to selective antagonists in vivo...
April 27, 2017: Developmental Neuroscience
https://www.readbyqxmd.com/read/28445880/heating-of-newborn-infants-due-to-blue-light-emitting-diode-fibreoptic-phototherapy-pads
#15
Pei Ling Ng, Tony Carlisle, Marleesa Ly, Scott Adam Morris
BACKGROUND: Surface temperatures of fibreoptic phototherapy pads using a high intensity blue light-emitting diode (LED) light source have not been studied. OBJECTIVES: The aim of this study was to measure the temperature of LED fibreoptic phototherapy pads during phototherapy in a bench-top study, and to determine temperature effects on babies during phototherapy. METHODS: A commercially available LED fibreoptic phototherapy system was tested...
April 27, 2017: Neonatology
https://www.readbyqxmd.com/read/28445876/impact-of-the-reclassification-of-the-non-invasive-follicular-variant-of-papillary-carcinoma-as-benign-on-the-malignancy-risk-of-the-bethesda-system-for-reporting-thyroid-cytopathology-a-meta-analysis-study
#16
Lester J Layfield, Zubair W Baloch, Magda Esebua, Rohini Kannuswamy, Robert L Schmidt
OBJECTIVES: The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) established diagnostic categories for cytologic specimens of the thyroid. Each category was associated with an estimated risk of malignancy. Recently, the non-invasive follicular variant of papillary thyroid carcinoma has been reclassified as benign. This reclassification may alter the malignancy risk of TBSRTC diagnostic categories. STUDY DESIGN: A literature search was made for all studies investigating the effect of reclassification of some non-invasive follicular variant papillary thyroid carcinomas as benign on the malignancy risk associated with TBSRTC categories...
April 27, 2017: Acta Cytologica
https://www.readbyqxmd.com/read/28445849/a-reference-measurement-procedure-for-amino-acids-in-blood-using-isotope-dilution-ultra-performance-liquid-chromatography-tandem-mass-spectrometry
#17
Juok Kim, Tran Thi Thanh Huong, Seon-Pyo Hong, Ji-Seon Jeong
We described a reference measurement procedure for amino acid (AA) quantification in blood samples based on deproteinization with 5-sulfosalicylic acid (SSA) and an isotope dilution-ultra performance liquid chromatography-tandem mass spectrometry (LC-MS) method. The serum was deproteinized with 15% v/v SSA and the supernatant was injected directly into the LC-MS system without further processing. Compared with the use of other precipitants and water as a control, five model AAs-valine, isoleucine, leucine, tyrosine, and phenylalanine-in the SSA-treated samples showed ionization enhancement as well as stable background signals without significant ion suppression effects...
April 17, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28445847/to-elute-or-not-to-elute-in-immunocapture-bottom-up-lc-ms
#18
Maren Christin Stillesby Levernæs, Marianne Nordlund Broughton, Léon Reubsaet, Trine Grønhaug Halvorsen
Immunocapture-based bottom-up LC-MS is a promising technique for the quantification of low abundant proteins. Magnetic immunocapture beads provide efficient enrichment from complex samples through the highly specific interaction between the target protein and its antibody. In this article, we have performed the first thorough comparison between digestion of proteins while bound to antibody coated beads versus after elution from the beads. Two previously validated immunocapture based MS methods for the quantification of pro-gastrin releasing peptide (ProGRP) and human chorionic gonadotropin (hCG) were used as model systems...
April 14, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28445834/light-harvesting-antenna-complexes-in-the-moss-physcomitrella-patens-implications-for-the-evolutionary-transition-from-green-algae-to-land-plants
#19
REVIEW
Masakazu Iwai, Makio Yokono
Plants have successfully adapted to a vast range of terrestrial environments during their evolution. To elucidate the evolutionary transition of light-harvesting antenna proteins from green algae to land plants, the moss Physcomitrella patens is ideally placed basally among land plants. Compared to the genomes of green algae and land plants, the P. patens genome codes for more diverse and redundant light-harvesting antenna proteins. It also encodes Lhcb9, which has characteristics not found in other light-harvesting antenna proteins...
April 23, 2017: Current Opinion in Plant Biology
https://www.readbyqxmd.com/read/28445823/engineering-metal-hydr-oxide-sorbents-for-removal-of-arsenate-and-similar-weak-acid-oxyanion-contaminants-a-critical-review-with-emphasis-on-factors-governing-sorption-processes
#20
Kiril D Hristovski, Jasmina Markovski
To create an integrative foundation for engineering of the next generation inexpensive sorbent systems, this critical review addresses the existing knowledge gap in factor/performance relationships between weak-acid oxyanion contaminants and metal (hydr)oxide sorbents. In-depth understanding of fundamental thermodynamics and kinetics mechanisms, material fabrication, and analytical and characterization techniques, is necessary to engineer sorbent that exhibit high capacity, selectivity, stability, durability and mass transport of contaminants under a wide range of operating and water matrix conditions requirements...
April 22, 2017: Science of the Total Environment
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