keyword
MENU ▼
Read by QxMD icon Read
search

Reinforcement learning

keyword
https://www.readbyqxmd.com/read/29045575/shared-and-disorder-specific-neurocomputational-mechanisms-of-decision-making-in-autism-spectrum-disorder-and-obsessive-compulsive-disorder
#1
Christina O Carlisi, Luke Norman, Clodagh M Murphy, Anastasia Christakou, Kaylita Chantiluke, Vincent Giampietro, Andrew Simmons, Michael Brammer, Declan G Murphy, David Mataix-Cols, Katya Rubia
Autism spectrum disorder (ASD) and obsessive-compulsive disorder (OCD) often share phenotypes of repetitive behaviors, possibly underpinned by abnormal decision-making. To compare neural correlates underlying decision-making between these disorders, brain activation of boys with ASD (N = 24), OCD (N = 20) and typically developing controls (N = 20) during gambling was compared, and computational modeling compared performance. Patients were unimpaired on number of risky decisions, but modeling showed that both patient groups had lower choice consistency and relied less on reinforcement learning compared to controls...
October 17, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/29045060/competency-assessment-form-to-improve-feedback
#2
Karen E Hauer, Holly Nishimura, Diego Dubon, Arianne Teherani, Christy Boscardin
BACKGROUND: In-training evaluation reports are a commonly used assessment method for clinical learners that can characterise the development of competence in essential domains of practice. Strategies to increase the usefulness and specificity of written narrative comments about learner performance in these reports are needed to guide their learning. Soliciting narrative comments by competency domain from supervising doctors on in-training evaluation reports could improve the quality of written feedback to students...
October 18, 2017: Clinical Teacher
https://www.readbyqxmd.com/read/29042315/-interleukin-1-beta-reduces-glua1-phosphorylation-and-its-surface-expression-during-memory-reconsolidation-and-alpha-melanocyte-stimulating-hormone-can-modulate-these-effects
#3
Ivana Machado, Helgi B Schiöth, Mercedes Lasaga, Teresa Scimonelli
Pro-inflammatory cytokines can affect cognitive processes such as learning and memory. Particularly, interleukin-1β (IL-1β) influences hippocampus-dependent memories. We previously reported that administration of IL-1β in dorsal hippocampus impaired contextual fear memory reconsolidation. This effect was reversed by the melanocortin alpha-melanocyte-stimulating hormone (α-MSH). Our results also demonstrated that IL-1β produced a significant decrease in glutamate release from dorsal hippocampus synaptosomes after reactivation of the fear memory...
October 14, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/29040494/beyond-reward-prediction-errors-human-striatum-updates-rule-values-during-learning
#4
Ian Ballard, Eric M Miller, Steven T Piantadosi, Noah D Goodman, Samuel M McClure
Humans naturally group the world into coherent categories defined by membership rules. Rules can be learned implicitly by building stimulus-response associations using reinforcement learning or by using explicit reasoning. We tested if the striatum, in which activation reliably scales with reward prediction error, would track prediction errors in a task that required explicit rule generation. Using functional magnetic resonance imaging during a categorization task, we show that striatal responses to feedback scale with a "surprise" signal derived from a Bayesian rule-learning model and are inconsistent with RL prediction error...
October 13, 2017: Cerebral Cortex
https://www.readbyqxmd.com/read/29037660/nmda-receptor-blockade-specifically-impedes-the-acquisition-of-incentive-salience-attribution
#5
Jonathan J Chow, Joshua S Beckmann
Glutamatergic signaling plays an important role in learning and memory. Using Pavlovian conditioned approach procedures, the mechanisms that drive stimulus-reward learning and memory have been investigated. However, there are instances where reward-predictive stimuli can function beyond being solely predictive and can be attributed with "motivational value" or incentive salience. Using a Pavlovian conditioned approach procedure consisting of two different but equally predictive stimuli (lever vs. tone) we investigated the role NMDA receptor function has in the attribution of incentive salience...
October 13, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/29035229/transductive-zero-shot-learning-with-adaptive-structural-embedding
#6
Yunlong Yu, Zhong Ji, Jichang Guo, Yanwei Pang
Zero-shot learning (ZSL) endows the computer vision system with the inferential capability to recognize new categories that have never seen before. Two fundamental challenges in it are visual-semantic embedding and domain adaptation in cross-modality learning and unseen class prediction steps, respectively. This paper presents two corresponding methods named Adaptive STructural Embedding (ASTE) and Self-PAced Selective Strategy (SPASS) for both challenges. Specifically, ASTE formulates the visual-semantic interactions in a latent structural support vector machine framework by adaptively adjusting the slack variables to embody different reliablenesses among training instances...
October 12, 2017: IEEE Transactions on Neural Networks and Learning Systems
https://www.readbyqxmd.com/read/29034482/deep-reinforcement-learning-for-automated-radiation-adaptation-in-lung-cancer
#7
Huan-Hsin Tseng, Yi Luo, Sunan Cui, Jen-Tzung Chien, Randall K Ten Haken, Issam El Naqa
PURPOSE: To investigate deep reinforcement learning (DRL) based on historical treatment plans for developing automated radiation adaptation protocols for non-small cell lung cancer (NSCLC) patients that aim to maximize tumor local control at reduced rates of radiation pneumonitis grade 2 (RP2). METHODS: In a retrospective population of 114 NSCLC patients who received radiotherapy, a 3-component neural networks framework was developed for deep reinforcement learning (DRL) of dose fractionation adaptation...
October 16, 2017: Medical Physics
https://www.readbyqxmd.com/read/29034318/mediodorsal-thalamic-neurons-mirror-the-activity-of-medial-prefrontal-neurons-responding-to-movement-and-reinforcement-during-a-dynamic-dnmtp-task
#8
Rikki L A Miller, Miranda J Francoeur, Brett M Gibson, Robert G Mair
The mediodorsal nucleus (MD) interacts with medial prefrontal cortex (mPFC) to support learning and adaptive decision-making. MD receives driver (layer 5) and modulatory (layer 6) projections from PFC and is the main source of driver thalamic projections to middle cortical layers of PFC. Little is known about the activity of MD neurons and their influence on PFC during decision-making. We recorded MD neurons in rats performing a dynamic delayed nonmatching to position (dDNMTP) task and compared results to a previous study of mPFC with the same task (Onos et al...
September 2017: ENeuro
https://www.readbyqxmd.com/read/29033802/the-neurobiological-mechanism-of-chemical-aversion-emetic-therapy-for-alcohol-use-disorder-an-fmri-study
#9
Ralph L Elkins, Todd L Richards, Robert Nielsen, Richard Repass, Henriettae Stahlbrandt, Hunter G Hoffman
A recent NIH epidemiology study found the lifetime prevalence of alcohol use disorder in the United States to be 29%. Alcohol drinking behavior is strongly "learned" via pleasure center activation/reinforcement. Alcohol craving is a powerful desire to drink alcoholic beverages. Craving was added as one of the defining criteria for alcohol use disorder in DSM5, and craving reduction is becoming an increasingly important treatment goal. In the current study, patients with alcohol use disorder received 10 days of inpatient multi-modal treatments at Schick Shadel Hospital (SSH) of Seattle...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/29031813/song-practice-as-a-rewarding-form-of-play-in-songbirds
#10
REVIEW
Lauren V Riters, Jeremy A Spool, Devin P Merullo, Allison H Hahn
In adult songbirds, the primary functions of song are mate attraction and territory defense; yet, many songbirds sing at high rates as juveniles and outside these primary contexts as adults. Singing outside primary contexts is critical for song learning and maintenance, and ultimately necessary for breeding success. However, this type of singing (i.e., song "practice") occurs even in the absence of immediate or obvious extrinsic reinforcement; that is, it does not attract mates or repel competitors. Here we review studies that support the hypothesis that song practice is stimulated and maintained by intrinsic reward mechanisms (i...
October 11, 2017: Behavioural Processes
https://www.readbyqxmd.com/read/29028264/teacheng-a-teaching-engine-for-genomics
#11
Minji Kim, Yeonsung Kim, Lei Qian, Jun S Song
Motivation: Bioinformatics is a rapidly growing field that has emerged from the synergy of computer science, statistics and biology. Given the interdisciplinary nature of bioinformatics, many students from diverse fields struggle with grasping bioinformatic concepts only from classroom lectures. Interactive tools for helping students reinforce their learning would be thus desirable. Here, we present an interactive online educational tool called TeachEnG (acronym for Teaching Engine for Genomics) for reinforcing key concepts in sequence alignment and phylogenetic tree reconstruction...
October 15, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29027478/educational-initiative-to-standardize-concussion-management-in-pediatric-primary-care
#12
Alex M Taylor, Lise E Nigrovic, Meredith L Saillant, Emily K Trudell, Jonathan R Modest, Madeleine Kuhn, Louis Vernacchio
Pediatric primary care providers report limited training and tools to manage concussion. We developed a learning community intervention for a large independent pediatric practice association affiliated with a university hospital to standardize concussion management and improve the use of consensus-based guidelines. The learning community included in-person and online didactics, followed by a web-based reinforcement platform to educate and train clinicians on our treatment algorithm and decision support tools...
October 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/29023832/pupil-dilation-indicates-the-coding-of-past-prediction-errors-evidence-for-attentional-learning-theory
#13
Stephan Koenig, Metin Uengoer, Harald Lachnit
The attentional learning theory of Pearce and Hall () predicts more attention to uncertain cues that have caused a high prediction error in the past. We examined how the cue-elicited pupil dilation during associative learning was linked to such error-driven attentional processes. In three experiments, participants were trained to acquire associations between different cues and their appetitive (Experiment 1), motor (Experiment 2), or aversive (Experiment 3) outcomes. All experiments were designed to examine differences in the processing of continuously reinforced cues (consistently followed by the outcome) versus partially reinforced, uncertain cues (randomly followed by the outcome)...
October 11, 2017: Psychophysiology
https://www.readbyqxmd.com/read/29019169/one-back-reinforcement-dissociates-implicit-procedural-and-explicit-declarative-category-learning
#14
J David Smith, Sonia Jamani, Joseph Boomer, Barbara A Church
The debate over unitary/multiple category-learning utilities is reminiscent of debates about multiple memory systems and unitary/dual codes in knowledge representation. In categorization, researchers continue to seek paradigms to dissociate explicit learning processes (yielding verbalizable rules) from implicit learning processes (yielding stimulus-response associations that remain outside awareness). We introduce a new dissociation here. Participants learned matched category tasks with a multidimensional, information-integration solution or a one-dimensional, rule-based solution...
October 10, 2017: Memory & Cognition
https://www.readbyqxmd.com/read/29017988/encouraging-physical-activity-in-patients-with-diabetes-intervention-using-a-reinforcement-learning-system
#15
Elad Yom-Tov, Guy Feraru, Mark Kozdoba, Shie Mannor, Moshe Tennenholtz, Irit Hochberg
BACKGROUND: Regular physical activity is known to be beneficial for people with type 2 diabetes. Nevertheless, most of the people who have diabetes lead a sedentary lifestyle. Smartphones create new possibilities for helping people to adhere to their physical activity goals through continuous monitoring and communication, coupled with personalized feedback. OBJECTIVE: The aim of this study was to help type 2 diabetes patients increase the level of their physical activity...
October 10, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/29017141/premonitory-urges-and-tics-in-tourette-syndrome-computational-mechanisms-and-neural-correlates
#16
REVIEW
Vasco A Conceição, Ângelo Dias, Ana C Farinha, Tiago V Maia
Tourette syndrome is characterized by open motor behaviors - tics - but another crucial aspect of the disorder is the presence of premonitory urges: uncomfortable sensations that typically precede tics and are temporarily alleviated by tics. We review the evidence implicating the somatosensory cortices and the insula in premonitory urges and the motor cortico-basal ganglia-thalamo-cortical loop in tics. We consider how these regions interact during tic execution, suggesting that the insula plays an important role as a nexus linking the sensory and emotional character of premonitory urges with their translation into tics...
October 7, 2017: Current Opinion in Neurobiology
https://www.readbyqxmd.com/read/29016461/social-learning-pathways-in-the-relation-between-parental-chronic-pain-and-daily-pain-severity-and-functional-impairment-in-adolescents-with-functional-abdominal-pain
#17
Amanda L Stone, Stephen Bruehl, Craig A Smith, Judy Garber, Lynn S Walker
Having a parent with chronic pain (CP) may confer greater risk for persistence of CP from childhood into young adulthood. Social learning, such as parental modeling and reinforcement, represents one plausible mechanism for the transmission of risk for CP from parents to offspring. Based on a 7-day pain diary in 154 pediatric patients with functional abdominal CP, we tested a model in which parental CP predicted adolescents' daily average CP severity and functional impairment (distal outcomes) via parental modeling of pain behaviors and parental reinforcement of adolescent's pain behaviors (mediators) and adolescents' cognitive appraisals of pain threat (proximal outcome representing adolescents' encoding of parents' behaviors)...
October 6, 2017: Pain
https://www.readbyqxmd.com/read/28993710/dose-dependent-expression-of-claudin-5-is-a-modifying-factor-in-schizophrenia
#18
C Greene, J Kealy, M M Humphries, Y Gong, J Hou, N Hudson, L M Cassidy, R Martiniano, V Shashi, S R Hooper, G A Grant, P F Kenna, K Norris, C K Callaghan, M dN Islam, S M O'Mara, Z Najda, S G Campbell, J S Pachter, J Thomas, N M Williams, P Humphries, K C Murphy, M Campbell
Schizophrenia is a neurodevelopmental disorder that affects up to 1% of the general population. Various genes show associations with schizophrenia and a very weak nominal association with the tight junction protein, claudin-5, has previously been identified. Claudin-5 is expressed in endothelial cells forming part of the blood-brain barrier (BBB). Furthermore, schizophrenia occurs in 30% of individuals with 22q11 deletion syndrome (22q11DS), a population who are haploinsufficient for the claudin-5 gene. Here, we show that a variant in the claudin-5 gene is weakly associated with schizophrenia in 22q11DS, leading to 75% less claudin-5 being expressed in endothelial cells...
October 10, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/28992149/using-an-online-quiz-based-reinforcement-system-to-teach-healthcare-quality-and-patient-safety-and-care-transitions-at-the-university-of-california
#19
Ulfat Shaikh, Nasim Afsar-Manesh, Alpesh N Amin, Brian Clay, Sumant R Ranji
Quality issue: Implementing quality improvement (QI) education during clinical training is challenging due to time constraints and inadequate faculty development in these areas. Initial assessment: Quiz-based reinforcement systems show promise in fostering active engagement, collaboration, healthy competition and real-time formative feedback, although further research on their effectiveness is required. Choice of solution: An online quiz-based reinforcement system to increase resident and faculty knowledge in QI, patient safety and care transitions...
October 1, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/28989010/global-health-education-for-medical-students-when-learning-objectives-include-research
#20
Alison M Bales, Anthony R Oddo, David J Dennis, Robert C Siska, Echo VanderWal, Harry VanderWal, Nompumelelo Dlamini, Ronald J Markert, Mary C McCarthy
BACKGROUND: The Luke Commission, a provider of comprehensive mobile health outreach in rural Swaziland, focuses on human immunodeficiency virus testing and prevention, including the performance of over 100 circumcisions weekly. Educational objectives for medical student global health electives are essential. Learning research methodology while engaging in clinical activities reinforces curriculum goals. Medical care databases can produce clinically significant findings affecting international health policy...
October 5, 2017: Journal of Surgical Education
keyword
keyword
23454
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"