keyword
MENU ▼
Read by QxMD icon Read
search

"Lung function"

keyword
https://www.readbyqxmd.com/read/29048464/differences-in-postoperative-changes-in-pulmonary-functions-following-segmentectomy-compared-with-lobectomy
#1
Hiroaki Nomori, Atsushi Shiraishi, Yue Cong, Hiroshi Sugimura, Shuji Mishima
OBJECTIVES: To clarify differences in postoperative changes in systemic and regional pulmonary functions between segmentectomy and lobectomy in patients with lung cancer, we compared the 2 procedures using lung perfusion scintigraphy with a fusion image of single-photon emission computed tomography and computed tomography. METHODS: This study is a retrospective matched cohort study of consecutively acquired data. Pulmonary function tests and perfusion single-photon emission computed tomography/computed tomography were conducted before surgery and 6 months after surgery to measure changes in forced expiratory volume in 1 s of a whole lung, contralateral lung and a lobe...
October 18, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/29047102/reactive-oxygen-species-in-copd-related-vascular-remodeling
#2
Li Zuo, Chia-Chen Chuang, Alexander D Clark, Davis E Garrison, Jamie L Kuhlman, David C Sypert
The pathogenesis of chronic obstructive pulmonary disease (COPD) is a multifaceted process involving the alteration of pulmonary vasculature. Such vascular remodeling can be associated with inflammation, shear stress, and hypoxia-conditions commonly seen in patients with lung diseases. Particularly, the overproduction of reactive oxygen species (ROS) in the diseased lungs contributes greatly to pulmonary vascular remodeling. ROS play an important role in vascular homeostasis, yet excessive ROS can alter pulmonary vasculature and impair lung function, as implicated in COPD at all stages...
2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/29045708/association-between-polycyclic-aromatic-hydrocarbon-exposure-and-peripheral-blood-mononuclear-cell-dna-damage-in-human-volunteers-during-fire-extinction-exercises
#3
Maria Helena Guerra Andersen, Anne Thoustrup Saber, Per Axel Clausen, Julie Elbæk Pedersen, Mille Løhr, Ali Kermanizadeh, Steffen Loft, Niels Ebbehøj, Åse Marie Hansen, Peter Bøgh Pedersen, Ismo Kalevi Koponen, Eva-Carina Nørskov, Peter Møller, Ulla Vogel
This study investigated a number of biomarkers, associated with systemic inflammation as well as genotoxicity, in 53 young and healthy subjects participating in a course to become firefighters, while wearing personal protective equipment (PPE). The exposure period consisted of a 3-day training course where the subjects participated in various live-fire training exercises. The subjects were instructed to extinguish fires of either wood or wood with electrical cords and mattresses. The personal exposure was measured as dermal polycyclic aromatic hydrocarbon (PAH) concentrations and urinary excretion of 1-hydroxypyrene (1-OHP)...
October 13, 2017: Mutagenesis
https://www.readbyqxmd.com/read/29045215/ventilation-in-preterm-infants-and-lung-function-at-8-years
#4
LETTER
Lex W Doyle, Sarath Ranganathan, Jeanie L Y Cheong
No abstract text is available yet for this article.
October 19, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29045214/ventilation-in-preterm-infants-and-lung-function-at-8-years
#5
LETTER
Imad R Makhoul, Tanya Mashiach, Tatiana Smolkin
No abstract text is available yet for this article.
October 19, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29045213/ventilation-in-preterm-infants-and-lung-function-at-8-years
#6
LETTER
(no author information available yet)
New England Journal of Medicine, Volume 377, Issue 16, Page 1599-1602, October 2017.
October 19, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/29043990/tumor-necrosis-factor-%C3%AE-and-procalcitonin-level-variations-in-the-serum-and-their-effects-on-organ-function-in-patients-with-severe-acute-pancreatitis-during-infected-stage
#7
Yanping Zhu
To investigate the changes of tumor necrosis factor-α (TNF-α) and procalcitonin (PCT) in the serum and their effects on organ function in patients with severe acute pancreatitis (SAP) during infected stage, aiming to provide a reference to individual treatment. 32 patients with SAP during infected stage admitted to the Digestive Department of The Second Affiliated Hospital of Zhengzhou University from April 2014 to May 2015 and also 30 volunteer normal people were recruited in this study. And 26 patients detected with positive pathogenic bacteria were grouped into group A and another 6 patients with negative pathogenic bacteria into group B and 30 normal people into group C...
July 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29043487/the-differences-in-spirometry-predictive-equations-in-classifying-presence-and-degree-of-lung-function-impairment-which-suit-fits-the-best
#8
Marija Vukoja, Aleksandar Bokan, Gordana Vujasinovic, Ivan Kopitovic
PURPOSE: The aim of this study was to compare the differences between three most commonly used predictive equations (PE): ECCS (European Community of Coal and Steel), the third National Health and Nutrition Examination Survey (NHANES III), and GLI (Global Lung Initiative) in healthy individuals and when grading severity of lung function impairment in patients with obstructive lung diseases. METHODS: The study included 200 healthy volunteers and 200 patients with obstructive lung diseases at the Institute for Pulmonary Diseases of Vojvodina...
October 17, 2017: Lung
https://www.readbyqxmd.com/read/29042607/abnormal-m1-m2-macrophage-phenotype-profiles-in-the-small-airway-wall-and-lumen-in-smokers-and-chronic-obstructive-pulmonary-disease-copd
#9
Mathew Suji Eapen, Philip M Hansbro, Kielan McAlinden, Richard Y Kim, Chris Ward, Tillie-Louise Hackett, Eugene H Walters, Sukhwinder Singh Sohal
We explore potential dysregulation of macrophage phenotypes in COPD pathogenesis through integrated study of human small airway tissue, bronchoalveolar lavage (BAL) and an experimental murine model of COPD. We evaluated human airway tissue and BAL from healthy controls, normal lung function smokers (NLFS), and COPD subjects. Both small airways and BAL cells were immunohistochemically stained with anti-CD68 for total macrophages and with anti-CD163 for M2, and anti-iNOS for M1 macrophages. Multiplex ELISA measured BAL cytokines...
October 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29042461/how-do-we-improve-training-in-pulmonary-physiology-and-the-interpretation-of-lung-function-tests
#10
EDITORIAL
Gerrard Phillips
No abstract text is available yet for this article.
October 17, 2017: Thorax
https://www.readbyqxmd.com/read/29042177/antibiotic-exposure-and-interpersonal-variance-mask-the-effect-of-ivacaftor-on-respiratory-microbiota-composition
#11
Anton Y Peleg, Jocelyn Choo, Katherine Langan, Deirdre Edgeworth, Dominic Keating, John Wilson, Geraint B Rogers, Tom Kotsimbos
BACKGROUND: G551D is a class III mutation of the cystic fibrosis transmembrane regulator (CFTR) that results in impaired chloride channel function in cystic fibrosis (CF). Ivacaftor, a CFTR-potentiating agent improves sweat chloride, weight, lung function, and pulmonary exacerbation rate in CF patients with G551D mutations, but its effect on the airway microbiome remains poorly characterised. METHODS: Twenty CF patients with at least one G551D mutation from a single centre were recruited to a 4month double-blind, placebo-controlled, crossover study of ivacaftor with 28days of active treatment...
October 14, 2017: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
https://www.readbyqxmd.com/read/29040210/anticholinergics-for-asthma-a-long-history
#12
Gustavo J Rodrigo
PURPOSE OF REVIEW: To provide a fast overview about the introduction and development of anticholinergic drugs in Western medicine to their current indications particularly in asthma. RECENT FINDINGS: Although short-acting muscarinic antagonists have been positioned in the last 15 years for the treatment of adults and children with moderate-to-severe acute asthma in the emergency setting (reducing the risk of hospital admissions and improving lung function), a growing body of evidence has recently emerged that positions the long-acting muscarinic anticholinergic tiotropium bromide as add-on therapy to at least inhaled corticosteroids (ICS) maintenance therapy in adults, adolescents, and children with symptomatic asthma...
October 16, 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/29039839/-the-role-of-integrated-assessment-of-the-indicators-of-external-respiration-function-in-cardiac-surgical-patients
#13
O V Kamenskaja, A S Klinkova, I Ju Loginova, V V Lomivorotov, D N Ponomarev, D V Habarov, V N Lomivorotov
This literature review dedicated to the importance of an integrated assessment of external respiratory function in cardiovascular diseases (CVDs), including an analysis of up-to-date techniques, such as spirometry, body plethysmography, examination of the diffusing capacity of the lung, determination of O2 consumption with evaluation of the effectiveness of pulmonary ventilation. It considers the pathogenetic components of impairments in pulmonary ventilation and gas exchange, which develop in different CVDs, as well as during and after cardiac surgery...
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/29039624/factors-associated-with-cessation-of-smoking-among-swiss-adults-between-1991-and-2011-results-from-the-sapaldia-cohort
#14
Diana Ayala-Bernal, Nicole Probst-Hensch, Thierry Rochat, Robert Bettschart, Otto Brändli, Pierre-Olivier Bridevaux, Luc Burdet, Martin Frey, Margaret Gerbase, Marco Pons, Thomas Rothe, Daiana Stolz, Jean-Marie Tschopp, Alexander Turk, Nino Künzli, Christian Schindler
INTRODUCTION: Smoking is still the most preventable cause of disease and premature death in Switzerland, as elsewhere. We aimed to assess the main determinants of smoking cessation in the population-based cohort of SAPALDIA (Swiss Cohort Study on Air Pollution and Lung and Heart Diseases in Adults). METHODS: The SAPALDIA study was initiated in 1991 with 9651 participants aged 18 to 60 years from eight areas (S1). Follow-up assessments were conducted in 2002 (S2; 8047 participants) and 2010/11 (S3; 6088 participants)...
October 17, 2017: Swiss Medical Weekly
https://www.readbyqxmd.com/read/29039559/matrine-in-association-with-fd%C3%A2-2-stimulates-f508del%C3%A2-cystic-fibrosis-transmembrane-conductance-regulator-activity-in-the-presence-of-corrector-vx809
#15
Barbara Marengo, Andrea Speciale, Lisa Senatore, Silvano Garibaldi, Francesca Musumeci, Erika Nieddu, Benedetta Pollarolo, Maria Adelaide Pronzato, Silvia Schenone, Mauro Mazzei, Cinzia Domenicotti
Cystic fibrosis is caused by mutations of the cystic fibrosis transmembrane conductance regulator (CFTR) gene, and the predominant mutation is termed Phe508del (F508del). Therapy for F508del‑CFTR patients is based on the use of Orkambi®, a combination of VX809 and VX770. However, though Orkambi leads to an improvement in the lung function of patients, a progressive reduction in its efficacy has been observed. In order to overcome this effect, the aim of the present study was to investigate the role of matrine and the in‑house compound FD‑2 in increasing the action of VX809 and VX770...
October 6, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/29039230/effect-of-prenatal-waterpipe-tobacco-smoke-on-airway-inflammation-in-murine-model-of-asthma-of-adult-offspring-mice
#16
Nour A Al-Sawalha, Hanadi F Al-Bo'ul, Karem H Alzoubi, Omar F Khabour, Vaidehi J Thanawala
OBJECTIVE: Worldwide popularity of waterpipe tobacco smoking has increased, including in pregnant women. This study investigates the effect of prenatal waterpipe tobacco smoke (WTS) exposure on airway inflammation in a murine model of asthma of adult offspring mice. MATERIALS AND METHODS: Pregnant BALB/c mice were exposed to fresh air or WTS, using a whole-body exposure system that mimics human use during WTS. Adult male offspring mice were divided into; (1) control (prenatal fresh air, postnatal ovalbumin sensitization and saline challenge), (2) postnatal Ova S/C (prenatal fresh air, postnatal ovalbumin sensitization and challenge (Ova S/C)), (3) prenatal WTS (prenatal WTS, postnatal ovalbumin sensitization and saline challenge) and (4) prenatal WTS + postnatal Ova S/C...
July 2017: Inhalation Toxicology
https://www.readbyqxmd.com/read/29039225/toxicological-impact-of-waterpipe-smoking-and-flavorings-in-the-oral-cavity-and-respiratory-system
#17
Fawad Javed, Shatha Subhi ALHarthi, Munerah Saleh BinShabaib, Sangeeta Gajendra, Georgios E Romanos, Irfan Rahman
Waterpipe smoking (WS), an emerging trend has major health concerns. It is prevalent worldwide as a recreational activity both indoors and outdoors. The aim of this review was to assess the impact of waterpipe smoke on the oral and respiratory system (oral cavity and pulmonary tissues). A number of studies have shown that periodontal health status is compromised in waterpipe smokers when compared with nonsmokers. Some studies have associated WS with oral premalignant and malignant lesions; however, due to the poor quality of these studies, the presented outcomes should be interpreted with caution...
October 17, 2017: Inhalation Toxicology
https://www.readbyqxmd.com/read/29037529/the-relationship-between-tobacco-smoke-exposure-and-airflow-obstruction-in-us-children-analysis-of-the-national-health-and-nutrition-examination-survey-2007-2012
#18
Stacey-Ann Whittaker Brown, Bian Liu, Emanuela Taioli
BACKGROUND: It has been difficult to determine the individual impact of pre and post-natal childhood tobacco smoke exposure (TSE) on childhood lung function, as children are often exposed to both. AIMS: To determine the association between current TSE, as measured by serum cotinine levels, and airflow obstruction (defined as the ratio of forced expiratory volume in one second and the forced vital capacity (FEV1/FVC) less than the lower limit of normal), while adjusting for self-reported prenatal TSE...
October 13, 2017: Chest
https://www.readbyqxmd.com/read/29037075/optimal-distance-of-multi-plane-sensor-in-three-dimensional-electrical-impedance-tomography
#19
Zhenhua Hao, Shihong Yue, Benyuan Sun, Huaxiang Wang
Electrical impedance tomography (EIT) is a visual imaging technique for obtaining the conductivity and permittivity distributions in the domain of interest. As an advanced technique, EIT has the potential to be a valuable tool for continuously bedside monitoring of pulmonary function. The EIT applications in any three-dimensional (3 D) field are very limited to the 3 D effects, i.e. the distribution of electric field spreads far beyond the electrode plane. The 3 D effects can result in measurement errors and image distortion...
October 16, 2017: Computer Assisted Surgery (Abingdon, England)
https://www.readbyqxmd.com/read/29036019/targeting-the-interleukin-4-and-interleukin-13-pathways-in-severe-asthma-current-knowledge-and-future-needs
#20
Amit D Parulekar, Christina C Kao, Zuzana Diamant, Nicola A Hanania
PURPOSE OF REVIEW: Severe asthma is a heterogeneous disease that can be classified into phenotypes and endotypes based upon clinical or biological characteristics. Interleukin (IL)-4 and IL-13 play a key role in type 2 (T2) asthma. This article reviews the signaling pathway of IL-4 and IL-13 and highlights its targeted therapy in severe asthma. RECENT FINDINGS: Several clinical trials of biologics targeting the IL-4/IL-13 pathway have recently been completed. In patients with severe, uncontrolled asthma, targeting IL-13 alone with biologics including lebrikizumab and tralokinumab has not shown consistent reduction in asthma exacerbations...
October 13, 2017: Current Opinion in Pulmonary Medicine
keyword
keyword
23444
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"