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https://www.readbyqxmd.com/read/28749019/the-association-of-non-alcoholic-fatty-liver-disease-with-lung-function-a-survey-design-analysis-using-propensity-score
#1
Min-Sun Kwak, Eunyoung Kim, Eun Jin Jang, Chang-Hoon Lee
BACKGROUND AND OBJECTIVE: Although both non-alcoholic fatty liver disease (NAFLD) and lung function are known to be associated with metabolic syndromes, few studies have evaluated the relationship between NAFLD and lung function. Our population-based study was conducted to investigate whether NAFLD, diagnosed by elevation of liver enzymes without other chronic liver disease or heavy alcohol drinking, is associated with lung function. METHODS: A survey design analysis was performed using national representative data of health and nutritional status of civilians in Korea (Korean National Health and Nutrition Examination Survey, KNHANES) between 2010 and 2012...
July 27, 2017: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/28749014/use-of-the-control-of-allergic-rhinitis-and-asthma-test-and-pulmonary-function-tests-to-assess-asthma-control-in-pregnancy
#2
Luís Amaral, Carla Martins, Alice Coimbra
INTRODUCTION: Asthma is one of the most prevalent chronic medical conditions to complicate pregnancy. Similarly, active management strategies that prioritise asthma control in this vulnerable population can have a far-reaching impact. AIM: To describe lung function parameters and results of the Control of Allergic Rhinitis and Asthma Test (CARAT) questionnaire in pregnant asthmatics and to analyse correlations between lung function tests and CARAT results. METHODS: All pregnant asthmatics who performed spirometry and CARAT between September 2014 and August 2015 were included...
July 27, 2017: Australian & New Zealand Journal of Obstetrics & Gynaecology
https://www.readbyqxmd.com/read/28748510/clinical-characteristics-of-autoimmune-rheumatic-disease-related-organizing-pneumonia
#3
Xin Dong, Yi Zheng, Li Wang, Wen-Hui Chen, Yun-Gang Zhang, Qiang Fu
To study the clinical characteristics of autoimmune rheumatic disease-related organizing pneumonia (AIRD-OP), the clinical presentation, radiological findings, treatment, and outcome of AIRD-OP patients were analyzed, in comparison with patients with cryptogenic organizing pneumonia (COP). A total of 131 OP patients were identified, including 57 cases of AIRD-OP, 35 cases of COP, and 39 cases of other disease-related OPs. Among AIRD-OP patients, 36 (63%) presented the symptoms of OP at onset. The primary disease of AIRDs included Sjogren's syndrome (38%), polymyositis/dermatomyositis (23%), rheumatoid arthritis (23%), and undifferentiated AIRD...
July 26, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28748188/arterial-stiffness-in-symptomatic-smokers-with-normal-lung-function
#4
Nicola Scichilone, Antonino Tuttolomondo, Carlo Maida, Alida Benfante, Jessica Peluso, Anna Cirrincione, Valerio Vassallo, Antonio Pinto
Chronic obstructive pulmonary disease (COPD) is associated with cardiovascular morbidity and mortality. Arterial stiffness and endothelial dysfunction index are validated surrogate cardiovascular markers and are increased in subjects with COPD. We tested whether increased arterial stiffness and endothelial dysfunction occur in symptomatic smokers with no evidence of bronchial obstruction. Clinical and lung functional assessments were conducted in smoker subjects with chronic respiratory symptoms and in COPD patients...
July 2017: ERJ Open Research
https://www.readbyqxmd.com/read/28747965/systemic-white-blood-cell-count-as-a-biomarker-associated-with-severity-of-chronic-obstructive-lung-disease
#5
Hyeon-Kyoung Koo, Hyung Koo Kang, Pamela Song, Hye Kyeong Park, Sung-Soon Lee, Hoon Jung
BACKGROUND: Chronic obstructive pulmonary disease (COPD), is a chronic inflammatory disorder. We evaluated whether white blood cell (WBC) count, is associated with the severity of COPD, independent of other inflammatory conditions, such as metabolic syndrome. METHODS: The WBC counts were compared between 1227 COPD patients and 8679 non-COPD adults older than 40. The relationships between the WBC count, lung function, and symptoms score in COPD patients, were determined, using general linear regression analyses...
July 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28747837/evaluation-of-pulmonary-functions-in-preschool-children-born-late-preterm
#6
İlkay Er, Ayla Günlemez, Zeynep Seda Uyan, Metin Aydoğan, Meral Oruç, Olcay Işık, Ayşe Engin Arısoy, Canan Baydemir, Ayşe Sevim Gökalp
AIM: The aim of this study was to evaluate the pulmonary functions of preschool children born late-preterm. MATERIAL AND METHODS: Children aged between 3-7 years who were born at 34(0/7-)36(6/7) weeks' gestation represented the target sample. Patients with a diagnosis of congenital cardiac, pulmonary and/or muscle diseases were excluded. Respiratory symptoms were evaluated using the modified asthma predictive index and International Study of Asthma and Allergies in Childhood criteria for children aged under and over 6 years, respectively...
June 2017: Türk Pediatri Arşivi
https://www.readbyqxmd.com/read/28747217/persistence-of-candida-dubliniensis-and-lung-function-in-patients-with-cystic-fibrosis
#7
Atqah AbdulWahab, Husam Salah, Prem Chandra, Saad J Taj-Aldeen
OBJECTIVES: Candida dubliniensis is an emerging yeast and demonstrated a high adherence property to cystic fibrosis respiratory tract. Therefore, it is important to determine the persistence of C. dubliniensis and to assess the possible relationship to the body mass index (BMI) and forced expiratory volume in 1st second (FEV1). RESULTS: Candida isolates were identified by MALDI-TOF MS to species level from 40/52 (76.9%) cystic fibrosis patients. C. dubliniensis was the most common organism isolated from 50/77 (65%) lower respiratory specimens of 29 patients...
July 26, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28747201/intravenous-superoxide-dismutase-as-a-protective-agent-to-prevent-impairment-of-lung-function-induced-by-high-tidal-volume-ventilation
#8
Nan-Chun Wu, Fan-Ting Liao, Hao-Min Cheng, Shih-Hsien Sung, Yu-Chun Yang, Jiun-Jr Wang
BACKGROUND: Positive-pressure mechanical ventilation is essential in assisting patients with respiratory failure in the intensive care unit and facilitating oxygenation in the operating room. However, it was also recognized as a primary factor leading to hospital-acquired pulmonary dysfunction, in which pulmonary oxidative stress and lung inflammation had been known to play important roles. Cu/Zn superoxide dismutase (SOD) is an important antioxidant, and possesses anti-inflammatory capacity...
July 26, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28745986/ventilation-in-extremely-preterm-infants-and-respiratory-function-at-8-years
#9
Lex W Doyle, Elizabeth Carse, Anne-Marie Adams, Sarath Ranganathan, Gillian Opie, Jeanie L Y Cheong
BACKGROUND: Assisted ventilation for extremely preterm infants (<28 weeks of gestation) has become less invasive, but it is unclear whether such developments in care are associated with improvements in short-term or long-term lung function. We compared changes over time in the use of assisted ventilation and oxygen therapy during the newborn period and in lung function at 8 years of age in children whose birth was extremely premature. METHODS: We conducted longitudinal follow-up of all survivors of extremely preterm birth who were born in Victoria, Australia, in three periods - the years 1991 and 1992 (225 infants), 1997 (151 infants), and 2005 (170 infants)...
July 27, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28745558/ambient-particulate-matter-may-affect-lung-function-of-motorcycle-taxi-drivers-in-bangkok
#10
Sara Arphorn, Tomohiro Ishimaru, Kunio Hara, Suwisa Mahasandana
PURPOSE: The motorcycle taxi drivers of Bangkok have been heavily exposed to high concentrations of PM10 and the impact of this on their lungs has been neither documented nor studied. This study examines the association between exposure to PM10 and lung function decline among motorcycle taxi drivers. METHODS: A cross-sectional study was conducted in Bangkok between two groups: a subject group of motorcycle taxi drivers and control group of enclosed vehicle taxi drivers...
July 26, 2017: Journal of the Air & Waste Management Association
https://www.readbyqxmd.com/read/28745524/should-patients-switched-from-d-to-b-in-the-gold-2017-classification-be-discontinued-from-inhaled-corticosteroids
#11
Matevz Harlander, Miriam Barrecheguren, Matjaz Turel, Marc Miravitlles
Inhaled corticosteroids (ICSs) are the cornerstone of the treatment of asthma, but their role in COPD is limited. Several guidelines recommend their use in patients with severe airflow limitation, frequent exacerbations and asthma-COPD overlap (ACO), while the previous GOLD document recommended ICS for patients with high risk of exacerbations and a high level of symptoms (group D). Following the changes in the GOLD document 2017 update, in which impaired lung function is no longer considered as a determinant of exacerbation risk, a high number of COPD patients can now be labeled as group B (low risk of exacerbations and high level of symptoms) instead of D, and hence, no longer fulfill the indication for ICS...
July 26, 2017: COPD
https://www.readbyqxmd.com/read/28744781/lung-function-in-pregnancy-in-langerhans-cell-histiocytosis
#12
Elżbieta Radzikowska, Elżbieta Wiatr, Monika Franczuk, Iwona Bestry, Kazimierz Roszkowski-Śliż
Pulmonary Langerhans cell histiocytosis (LCH) is a rare disease, affecting usually young people. The course of the disease is variable. In some pulmonary LCH patients a severe lung destruction and progression in spite of chemotherapy is observed, but in others just a cessation of smoking induces a regression of the disease. In the present study we seek to determine the influence of pregnancy on pulmonary function in LCH patients, an unchartered area of research. We addressed the issue by investigating eight pregnant women out of the 45 women hospitalized with the diagnosis of pulmonary LCH in the period from 2000 to 2015...
July 26, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28744118/voluntary-lung-function-screening-to-reveal-new-copd-cases-in-southern-italy
#13
Alberto Capozzolo, Giorgio Castellana, Silvano Dragonieri, Pierluigi Carratù, Vito Liotino, Maria Rosaria Vulpi, Lorenzo Marra, Emanuela Resta, Pierluigi Intiglietta, Onofrio Resta
BACKGROUND: Underdiagnosis of COPD is a relevant issue, and most frequently involves patients at early stages of the disease. Physicians do not routinely recommend smokers to undergo spirometry, unless they are symptomatic. AIMS: To investigate the effectiveness of voluntary lung function screening in bringing to light patients with previously unknown COPD and to evaluate the relationships among symptoms, smoking status, and airway obstruction. METHODS: A voluntary screening study for COPD was conducted during two editions of the annual Fiera del Levante (2014 and 2015), an international trade fair in Bari...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28744034/comparison-of-the-effects-of-core-stabilization-and-chest-mobilization-exercises-on-lung-function-and-chest-wall-expansion-in-stroke-patients
#14
Shin-Jun Park, Ju-Hwan Lee, Kyung-Ok Min
[Purpose] The main purpose of this study was to compare the effects of core stabilization and chest mobilization exercises on pulmonary function and chest expansion in chronic stroke patients. [Subjects and Methods] Thirty stroke patients were randomly divided into two groups: a core stabilization exercise group (n=15) and a chest mobilization exercise group (n=15). Each exercise was performed 3 times per week for 30 minutes for 4 weeks, and pulmonary function and chest expansion when breathing were measured for both groups...
July 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28743913/microrna-200b-regulates-distal-airway-development-by-maintaining-epithelial-integrity
#15
Naghmeh Khoshgoo, Robin Visser, Landon Falk, Chelsea A Day, Dustin Ameis, Barbara M Iwasiow, Fuqin Zhu, Arzu Öztürk, Sujata Basu, Molly Pind, Agnes Fresnosa, Mike Jackson, Vinaya Kumar Siragam, Gerald Stelmack, Geoffrey G Hicks, Andrew J Halayko, Richard Keijzer
miR-200b plays a role in epithelial-to-mesenchymal transition (EMT) in cancer. We recently reported abnormal expression of miR-200b in the context of human pulmonary hypoplasia in congenital diaphragmatic hernia (CDH). Smaller lung size, a lower number of airway generations, and a thicker mesenchyme characterize pulmonary hypoplasia in CDH. The aim of this study was to define the role of miR-200b during lung development. Here we show that miR-200b(-/-) mice have abnormal lung function due to dysfunctional surfactant, increased fibroblast-like cells and thicker mesenchyme in between the alveolar walls...
July 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28743305/prognosis-and-longitudinal-changes-of-physical-activity-in-idiopathic-pulmonary-fibrosis
#16
Thomas Bahmer, Anne-Marie Kirsten, Benjamin Waschki, Klaus F Rabe, Helgo Magnussen, Detlef Kirsten, Marco Gramm, Simone Hummler, Eva Brunnemer, Michael Kreuter, Henrik Watz
BACKGROUND: Physical activity (PA) is associated with disease severity in idiopathic pulmonary fibrosis (IPF), but longitudinal studies evaluating its prognostic value and changes over time are lacking. METHODS: We measured PA (steps per day, SPD) in a cohort of 46 IPF-patients (mean age, 67 years; mean FVC, 76.1%pred.) by accelerometry at baseline, recorded survival status during 3 years follow-up and repeated measurements in survivors. We compared the prognostic value of PA to established mortality predictors including lung function (FVC, DLCO) and 6-min walking-distance (6MWD)...
July 25, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28740854/clinical-implications-of-oscillatory-lung-function-during-methacholine-bronchoprovocation-testing-of-preschool-children
#17
Sun Hee Choi, Youn Ho Sheen, Mi Ae Kim, Ji Hyeon Baek, Hey Sung Baek, Seung Jin Lee, Jung Won Yoon, Yeong Ho Rha, Man Yong Han
OBJECTIVE: To investigate the repeatability and safety of measuring impulse oscillation system (IOS) parameters and the point of wheezing during bronchoprovocation testing of preschool children. METHODS: Two sets of methacholine challenge were conducted in 36 asthma children. The test was discontinued if there was a significant change in reactance (Xrs5) and resistance (Rrs5) at 5 Hz (Condition 1) or respiratory distress due to airway obstruction (Condition 2)...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28740686/whole-lung-lavage-technical-details-challenges-and-management-of-complications
#18
REVIEW
Ahmed Awab, Muhammad S Khan, Houssein A Youness
Pulmonary alveolar proteinosis (PAP) is a rare disease characterized by alveolar accumulation of surfactant material with resulting hypoxemia and reduced lung function. Whole lung lavage (WLL) to physically remove the proteinaceous material from the affected lung is the standard treatment. Since its original description in 1964, there have been increasing numbers of WLL procedures done worldwide and the technique has been variously refined and modified. When done in experienced centers, WLL provides long lasting benefit in the majority of patients...
June 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28740685/minimally-invasive-aortic-valve-replacement-in-high-risk-patient-groups
#19
REVIEW
Daniel Fudulu, Harriet Lewis, Umberto Benedetto, Massimo Caputo, Gianni Angelini, Hunaid A Vohra
Minimally invasive aortic valve replacement (AVR) aims to preserve the sternal integrity and improve postoperative outcomes. In low risk patients, this technique can be achieved with comparable mortality to the conventional approach and there is evidence of possible reduction in intensive care and hospital length of stay, transfusion requirement, renal dysfunction, improved respiratory function and increased patient satisfaction. In this review, we aim to asses if these benefits can be transferred to the high risk patient groups...
June 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28740672/effectiveness-of-perioperative-pulmonary-rehabilitation-in-thoracic-surgery
#20
Attila Vagvolgyi, Zsolt Rozgonyi, Maria Kerti, Paul Vadasz, Janos Varga
BACKGROUND: Functional condition is crucial for operability of patients with lung cancer and/or chronic respiratory diseases. The aim of the study was to measure changes of functional and quality of life parameters in terms of the effectiveness of perioperative pulmonary rehabilitation (PR). METHODS: A total of 208 COPD patients (age: 63±9 years, man/woman: 114/94, FEV1: 62±14%pred) participated in a perioperative PR program. The indication was primary lung cancer in 72% of the patients...
June 2017: Journal of Thoracic Disease
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