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https://www.readbyqxmd.com/read/29783036/retrospective-study-on-the-management-and-follow-up-of-18-patients-with-a-mid-urethral-sling-penetrating-the-urethra-or-bladder
#1
Edouard Goujon, Adélaide Jarniat, Florian Bardet, Lise Bergogne, Emmanuel Delorme
INTRODUCTION: The mid-urethral sling (MUS) procedure is the gold-standard for the surgical treatment of stress urinary incontinence (SUI). Urethro-vesical sling exposure is one of the most serious complications of this procedure. We describe the treatment and follow-up of 18 patients with bladder or urethral sling exposure. PATIENTS AND METHODS: This single-center, retrospective study assessed the diagnosis and management of MUS penetrating the lower urinary tract in 18 women...
May 18, 2018: Journal of gynecology obstetrics and human reproduction
https://www.readbyqxmd.com/read/29782692/the-influence-of-chemical-modification-on-linker-rotational-dynamics-in-metal-organic-frameworks
#2
Joshua Damron, Jialiu Ma, Ricardo Kurz, Kay Saalwaechter, Adam Matzger, Ayyalusamy Ramamoorthy
The robust synthetic flexibility of metal-organic frameworks (MOFs) offers a promising class of tailorable materials, for which, the ability to tune specific physicochemical properties is highly desired. This is achievable only through a thorough description of the consequences for chemical manipulations both in structure and dynamics. Magic angle spinning solid-state NMR spectroscopy offers many modalities in this pursuit, particularly for dynamic studies. Herein, we employ a separated-local-field NMR approach to show how specific intra-framework chemical modifications to MOF UiO66 heavily modulate the dynamic evolution of the organic ring moiety over several orders of magnitude...
May 21, 2018: Angewandte Chemie
https://www.readbyqxmd.com/read/29782659/self-suspended-nanomesh-scaffold-for-ultrafast-flexible-photodetectors-based-on-organic-semiconducting-crystals
#3
Lei Zhang, Nadiia Pasthukova, Yifan Yao, Xiaolan Zhong, Egon Pavlica, Gvido Bratina, Emanuele Orgiu, Paolo Samorì
Self-standing nanostructures are of fundamental interest in materials science and nanoscience and are widely used in (opto-)electronic and photonic devices as well as in micro-electromechanical systems. To date, large-area and self-standing nanoelectrode arrays assembled on flexible substrates have not been reported. Here the fabrication of a hollow nanomesh scaffold on glass and plastic substrates with a large surface area over 1 mm2 and ultralow leakage current density (≈1-10 pA mm-2 @ 2 V) across the empty scaffold is demonstrated...
May 21, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29782648/patient-preferences-for-topical-treatment-of-actinic-keratoses-a-discrete-choice-experiment
#4
D Kopasker, A Kwiatkowski, R N Matin, C A Harwood, F Ismail, J T Lear, J Thomson, Z Hasan, G N Wali, A Milligan, L Crawford, I Ahmed, H Duffy, C M Proby, P F Allanson
BACKGROUND: Treatment of actinic keratoses (AK) is a potentially effective strategy for prevention of cutaneous squamous cell carcinoma (cSCC). However, the patient perspective on potential benefits of AK treatment in terms of skin cancer reduction has received little attention to date. OBJECTIVES: (1) To investigate patient preferences for AK topical treatments using a discrete choice experiment (DCE); (2) To evaluate patient willingness to trade between clinical benefit and medical burden...
May 21, 2018: British Journal of Dermatology
https://www.readbyqxmd.com/read/29782613/on-the-optimization-of-low-cost-fdm-3d-printers-for-accurate-replication-of-patient-specific-abdominal-aortic-aneurysm-geometry
#5
Michael Chung, Norbert Radacsi, Colin Robert, Edward D McCarthy, Anthony Callanan, Noel Conlisk, Peter R Hoskins, Vasileios Koutsos
Background: There is a potential for direct model manufacturing of abdominal aortic aneurysm (AAA) using 3D printing technique for generating flexible semi-transparent prototypes. A patient-specific AAA model was manufactured using fused deposition modelling (FDM) 3D printing technology. A flexible, semi-transparent thermoplastic polyurethane (TPU), called Cheetah Water (produced by Ninjatek, USA), was used as the flexible, transparent material for model manufacture with a hydrophilic support structure 3D printed with polyvinyl alcohol (PVA)...
2018: 3D Print Med
https://www.readbyqxmd.com/read/29782550/multiple-roles-of-core-protein-linker-in-hepatitis-b-virus-replication
#6
Kuancheng Liu, Laurie Luckenbaugh, Xiaojun Ning, Ji Xi, Jianming Hu
Hepatitis B virus (HBV) core protein (HBc) contains an N-terminal domain (NTD, assembly domain) and a C-terminal domain (CTD), which are linked by a flexible linker region. HBc plays multiple essential roles in viral replication, including capsid assembly, packaging of the viral pregenomic RNA (pgRNA) into nucleocapsids, viral reverse transcription that converts pgRNA to the genomic DNA, and secretion of DNA-containing (complete) virions or genome-free (empty) virions. The HBc linker is generally assumed to act merely as a spacer between NTD and CTD but some results suggest that the linker may affect NTD assembly...
May 21, 2018: PLoS Pathogens
https://www.readbyqxmd.com/read/29782373/compliance-and-high-reliability-in-a-complex-healthcare-organization
#7
Maxine dellaBadia Simon
When considering the impact of regulation on healthcare, visualize a spider's web. The spider weaves sections together to create the whole, with each fiber adding to the structure to support its success or lead to its failure. Each section is dependent on the others, and all must be aligned to maintain the structure. Outside forces can cause a shift in the web's fragile equilibrium.The interdependence of the sections of the spider's web is similar to the way hospital departments and services work together. An organization's structure must be shaped to support its mission and vision...
2018: Frontiers of Health Services Management
https://www.readbyqxmd.com/read/29782181/effectiveness-of-an-osteopathic-abdominal-manual-intervention-in-pain-thresholds-lumbopelvic-mobility-and-posture-in-women-with-chronic-functional-constipation
#8
María José Martínez-Ochoa, Juan Carlos Fernández-Domínguez, Jose Miguel Morales-Asencio, Javier González-Iglesias, François Ricard, Ángel Oliva-Pascual-Vaca
OBJECTIVES: To assess the effect of an osteopathic abdominal manual intervention (AMI) on pressure pain thresholds (PPTs), mobility, hip flexibility, and posture in women with chronic functional constipation. DESIGN: Randomized, double-blind placebo-controlled trial. SETTING/LOCATION: Subjects were recruited for the study by referral from different gastroenterology outpatient clinics in the city of Madrid (Spain). SUBJECTS: Sixty-two patients suffering from chronic functional constipation according to the guidelines of the Congress of Rome III...
May 21, 2018: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/29782170/structure-and-dynamics-of-water-confined-in-imogolite-nanotubes
#9
Laura Scalfi, Guillaume Fraux, Anne Boutin, François-Xavier Coudert
We have studied the properties of water adsorbed inside nanotubes of hydrophilic imogolite, an aluminium silicate clay mineral, by means of molecular simulations. We used a classical force field to describe the water and the flexible imogolite nanotube, and validated it against data obtained from first-principles molecular dynamics. With it, we observe a strong structuration of the water confined in the nanotube, with specific adsorption sites and a distribution of hydrogen bond patterns. The combination of number of adsorption sites, their geometry and the preferential tetrahedral hydrogen bonding pattern of water leads to frustration and disorder...
May 21, 2018: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/29781908/musculoskeletal-injury-in-paddle-sport-athletes
#10
Andrew R Griffin, Diana M Perriman, Teresa M Neeman, Paul N Smith
INTRODUCTION: Kayak racing has been an Olympic sport since 1936. The sport is evolving with the introduction of ocean skis and stand-up-paddle boards (SUP). Musculoskeletal injury incidence surveys have been conducted for ultra-marathon events, but no data have been published for other racing formats. OBJECTIVE: To identify and compare the rates and types of injuries sustained by paddling athletes as a function of discipline and training parameters in Sprint, Marathon, Ultra-Marathon, and Ocean events...
May 16, 2018: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29781907/novel-interventions-for-recalcitrant-achilles-tendinopathy-benefits-seen-following-high-volume-image-guided-injection-or-extracorporeal-shockwave-therapy-a-prospective-cohort-study
#11
Patrick C Wheeler, Chloe Tattersall
OBJECTIVE: To compare the outcomes for patients with chronic noninsertional Achilles tendinopathy following extracorporeal shockwave therapy (ESWT) and high-volume image-guided injection (HVIGI). DESIGN: Prospective cohort study. SETTING: Hospital-based Sports Medicine Outpatient Clinic. PATIENTS: Sixty-three consecutive patients with chronic noninsertional Achilles tendinopathy, treated with ESWT (n = 22) or HVIGI (n = 41), with minimum 3-month follow-up...
May 16, 2018: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29781831/same-sex-and-different-sex-parent-families-in-italy-is-parents-sexual-orientation-associated-with-child-health-outcomes-and-parental-dimensions
#12
Roberto Baiocco, Nicola Carone, Salvatore Ioverno, Vittorio Lingiardi
OBJECTIVE: Seventy gay fathers through surrogacy, 125 lesbian mothers through donor insemination, and 195 heterosexual parents through spontaneous conception, all with children aged 3 to 11 years and living in Italy, were compared on children's psychological adjustment and prosocial behavior, as well as parental self-efficacy, dyadic adjustment, family cohesion, and flexibility. Associations among family structures, family processes, and child health outcomes were also tested. METHODS: Participants were matched for child characteristics...
May 16, 2018: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29781651/exposure-and-cbt-for-chronic-back-pain-an-rct-on-differential-efficacy-and-optimal-length-of-treatment
#13
Julia Anna Glombiewski, Sebastian Holzapfel, Jenny Riecke, Johan W S Vlaeyen, Jeroen de Jong, Gunnar Lemmer, Winfried Rief
OBJECTIVE: Our aim was to establish whether Exposure, a specialized tailored treatment for chronic low back pain, has any advantages over cognitive-behavioral therapy (CBT) among individuals with high fear-avoidance levels. Second, we planned to compare short and long versions of Exposure. Third, we aimed to investigate whether Exposure can be delivered in an outpatient psychological setting. METHOD: A total of 88 Caucasian participants (55% women) were randomized to three different psychological treatment conditions, Exposure-long, Exposure-short, and CBT...
June 2018: Journal of Consulting and Clinical Psychology
https://www.readbyqxmd.com/read/29781613/rational-design-of-the-first-lead-tin-fluorooxoborates-mb2o3f2-m-pb-sn-containing-flexible-two-dimensional-b6o12f6-%C3%A2-single-layers-with-widely-divergent-second-harmonic-generation-effects
#14
Min Luo, Fei Liang, Yunxia Song, Dan Zhao, Ning Ye, Zheshuai Lin
Molecular engineering design is a productive strategy on atomic-scale to optimize crystal structure and develop new-functional materials. Herein, the first lead/tin fluorooxoborates, MB2O3F2 (M=Pb, Sn), were rationally designed by employing the nonlinear optical crystal Sr2Be2B2O7 (SBBO) as a parent model. Compared with the rigid [Be6B6O15]∞ double layers in SBBO, MB2O3F2 have flexible two-dimensional [B6O12F6]∞ single layer, which not only keeps the NLO-favorable layered structure but also overcomes the structural instability issues of SBBO...
May 21, 2018: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/29781475/conformationally-flexible-and-moderately-electron-donating-units-installed-d-a-d-triad-enabling-multicolor-changing-mechanochromic-luminescence-tadf-and-room-temperature-phosphorescence
#15
Youhei Takeda, Takahito Kaihara, Masato Okazaki, Heather Higginbotham, Przemyslaw Data, Norimitsu Tohnai, Satoshi Minakata
A novel twisted donor-acceptor-donor (D-A-D) π-conjugated compound that contains flexible and moderately-electron-donating units has been designed and synthesized. It exhibited not only multi-color-changing mechanochromic luminescence and thermally activated delayed fluorescence, but also, unexpectedly, room-temperature phosphorescence in a host layer.
May 21, 2018: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/29781448/flexible-self-powered-piezo-supercapacitor-system-for-wearable-electronics
#16
Evgenia Gilshteyn, Daler Amanbaev, Maxim Silibin, Artem Sysa, Vladislav Kondrashov, Anton Anisimov, Tanja Kallio, Albert Nasibulin
The integration of the energy harvesting and energy storage in a single device both enables the conversion of the ambient energy into electricity and provides a sustainable power source for various electronic devices and systems. On the other hand, mechanical flexibility coupled with optical transparency of the energy storage devices is required for many applications, ranging from self-powered rolled-up displays to wearable optoelectronic devices. We integrate a piezoelectric poly(vinylidene-trifluoroethylene) film into a flexible supercapacitor system to harvest and store the energy...
May 21, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29781446/pyro-phototronic-nanogenerator-based-on-flexible-2d-zno-graphene-heterojunction-and-its-application-in-self-powered-near-infrared-photodetector-and-active-analog-frequency-modulation
#17
Parikshit Sahatiya, Akash Shinde, Sushmee Badhulika
Even though 2D ZnO has been utilized for enhanced self-powered sensing by strain modulation due to its piezoelectric property, study on utilizing pyroelectric property of ZnO remains unexplored. The piezoelectric property of 2D ZnO works on mechanical strain which disrupts the structure of ZnO leading to the failure of device. For pyroelectric nanogenerator, temperature difference can be triggered by external light source which does not disrupt the ZnO structure and also avoids the need for physical bending/pressing as in case of piezoelectric nanogenerator...
May 21, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29781370/re-treatment-of-an-unruptured-anterior-communicating-artery-aneurysm-using-the-new-pconus-2-device-description-of-a-case
#18
Marco Varrassi, Sergio Carducci, Aldo V Giordano, Carlo Masciocchi
Endovascular approach represents today the first option in treatment of ruptured and unruptured cerebral aneurysms. Nevertheless, wide-neck bifurcation aneurysms still represent a technical challenge for endovascular treatment due to the need to protect vessels arising next to the aneurysmal neck. A variety of devices have been implemented to ensure adequate assistance for coiling of these lesions. Among these devices, the new pCONus 2 represents an evolution of the well-known pCONus; compared to the previous one in fact, it allows a degree of articulation and flexibility between the shaft and the distal part (crown), making it more suitable for treatment of aneurysms presenting an angle between the longitudinal axis of the dome and parent vessel...
January 1, 2018: Interventional Neuroradiology
https://www.readbyqxmd.com/read/29781102/hierarchical-deep-convolutional-neural-networks-combine-spectral-and-spatial-information-for-highly-accurate-raman-microscopy-based-cytopathology
#19
Sascha D Krauß, Raphael Roy, Hesham K Yosef, Tatjana Lechtonen, Samir F El-Mashtoly, Klaus Gerwert, Axel Mosig
Hierarchical variants of so-called deep convolutional neural networks (DCNNs) have facilitated breakthrough results for numerous pattern recognition tasks in recent years. We assess the potential of these novel whole-image classifiers for Raman microscopy based cytopathology. Conceptually, DCNNs facilitate a flexible combination of spectral and spatial information for classifying cellular images as healthy or cancer affected cells. As we demonstrate, this conceptual advantage translates into practice, where DCNNs exceed the accuracy of both conventional classifiers based on pixel spectra as well as classifiers based on morphological features extracted from Raman microscopic images...
May 21, 2018: Journal of Biophotonics
https://www.readbyqxmd.com/read/29781041/a-bead-based-immunogold-silver-staining-assay-on-capillary-driven-microfluidics
#20
Ngoc M Pham, Sebastian Rusch, Yuksel Temiz, Robert D Lovchik, Hans-Peter Beck, Walter Karlen, Emmanuel Delamarche
Point-of-care (POC) diagnostics are critically needed for the detection of infectious diseases, particularly in remote settings where accurate and appropriate diagnosis can save lives. However, it is difficult to implement immunoassays, and specifically immunoassays relying on signal amplification using silver staining, into POC diagnostic devices. Effective immobilization of antibodies in such devices is another challenge. Here, we present strategies for immobilizing capture antibodies (cAbs) in capillary-driven microfluidic chips and implementing a gold-catalyzed silver staining reaction...
May 21, 2018: Biomedical Microdevices
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