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https://www.readbyqxmd.com/read/28327690/kyasanur-forest-disease-kfd-rare-disease-of-zoonotic-origin
#1
M Muraleedharan
Kyasanur forest disease (KFD) is a rare tick borne zoonotic disease that causes acute febrile hemorrhagic illness in humans and monkeys especially in southern part of India. The disease is caused by highly pathogenic KFD virus (KFDV) which belongs to member of the genus Flavivirus and family Flaviviridae. The disease is transmitted to monkeys and humans by infective tick Haemaphysalisspinigera. Seasonal outbreaks are expected to occur during the months of January to June. The aim of this paper is to briefly summarize the epidemiology, mode of transmission of KFD virus, clinical findings, diagnosis, treatment, control and prevention of the disease...
September 2016: Journal of Nepal Health Research Council
https://www.readbyqxmd.com/read/28323557/seroprevalence-of-severe-fever-with-thrombocytopenia-syndrome-virus-in-hedgehog-from-china
#2
Yue Sun, Miao-Miao Liu, Li-Mei Luo, Li Zhao, Hong-Ling Wen, Zhen-Tang Zhang, Jian-Wei Liu, Zai-Feng Xue, Dong-Qiang Ma, Shu-Jun Ding, Xiao-Ying Lei, Xue-Jie Yu
Severe fever with thrombocytopenia syndrome, an emerging hemorrhagic fever, is caused by severe fever with thrombocytopenia syndrome virus (SFTSV), a tick-borne bunyavirus. Information regarding SFTSV animal hosts is very limited. In this study, we showed that 64% (9/14) of hedgehogs in Shandong Province, China were seropositive to SFTSV antibody, suggesting that hedgehog could be a vertebrate parasitifer for SFTSV.
March 21, 2017: Vector Borne and Zoonotic Diseases
https://www.readbyqxmd.com/read/28322187/influence-of-genetic-background-on-hematologic-and-histopathologic-alterations-during-acute-granulocytic-anaplasmosis-in-129-svev-and-c57bl-6j-mice-lacking-type-i-and-type-ii-interferon-signaling
#3
Jennifer L Johns Marielle L Discipulo Amanda L Koehne Kaitlin A Moorhead And Claude M Nagamine
The role of host type I IFN signaling and its interaction with other immune pathways during bacterial infections is incompletelyunderstood. Type II IFN signaling plays a key role during numerous bacterial infections including granulocytic anaplasmosis (GA)caused by Anaplasma phagocytophilum infection. The function of combined type I and type II IFN signaling and their potentialsynergism during GA and similar tick-borne diseases is a topic of current research investigation. The goal of this study was toevaluate 2 mouse models of absent type I/type II IFN signaling in experimental A...
March 20, 2017: Comparative Medicine
https://www.readbyqxmd.com/read/28320144/magnetic-resonance-imaging-and-clinical-findings-in-adults-with-tick-borne-encephalitis
#4
Alexander Pichler, Johann Sellner, Gayane Harutyunyan, Astrid Sonnleitner, Daniela Sabine Klobassa, Juan-Jose Archelos-Garcia, Hannah Rock, Thomas Gattringer, Franz Fazekas
BACKGROUND: Magnetic resonance imaging (MRI) in tick-borne encephalitis (TBE) is often performed for differential diagnosis, but only a few reports on the morphologic changes in TBE patients and their relation to the disease severity exist. METHODS: We retrospectively searched for all TBE patients who were admitted to the Departments of Neurology of the Medical University of Graz (Austria) and the Paracelsus Medical University of Salzburg (Austria) between 2003 and 2014...
April 15, 2017: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/28319627/what-s-eating-you-lone-star-tick-amblyomma-americanum
#5
H Harris Reynolds, Dirk M Elston
Amblyomma americanum, also known as the lone star tick, is found in much of the eastern United States. Since the mid-20th century, the lone star tick has been implicated in human disease. Today, A americanum remains an important vector for tick-borne illness. In addition to others, species of Rickettsia, Ehrlichia, and Borrelia are all transmitted by the lone star tick. Recently described conditions such as Southern tick-associated rash illness and anaphylaxis to red meat following tick bites have been attributed to the lone star tick...
February 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28316419/comparison-between-conventional-and-molecular-methods-for-diagnosis-of-bovine-babesiosis-babesia-bovis-infection-in-tick-infested-cattle-in-upper-egypt
#6
Amira A T Al-Hosary
Ticks and tick-borne diseases are the main problems affecting the livestock production in Egypt. Bovine babesiosis has adverse effects on the animal health and production. A comparison of Giemsa stained blood smears, polymerase chain reaction (PCR) and nested PCR (nPCR) assays for detection of Babesia bovis infection in Egyptian Baladi cattle (Bos taurus) in reference to reverse line blot was carried out. The sensitivity of PCR and nested PCR (nPCR) assays were 65 and 100 % respectively. Giemsa stained blood smears showed the lowest sensitivity (30 %)...
March 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/28316015/expression-and-characterization-of-codon-optimized-crimean-congo-hemorrhagic-fever-virus-gn-glycoprotein-in-insect-cells
#7
Mehdi Rahpeyma, Alireza Samarbaf-Zadeh, Manoochehr Makvandi, Ata A Ghadiri, Stuart D Dowall, Fatemeh Fotouhi
Crimean-Congo hemorrhagic fever virus (CCHFV) is a major cause of tick-borne viral hemorrhagic disease in the world. Despite of its importance as a deadly pathogen, there is currently no licensed vaccine against CCHF disease. The attachment glycoprotein of CCHFV (Gn) is a potentially important target for protective antiviral immune responses. To characterize the expression of recombinant CCHFV Gn in an insect-cell-based system, we developed a gene expression system expressing the full-length coding sequence under a polyhedron promoter in Sf9 cells using recombinant baculovirus...
March 18, 2017: Archives of Virology
https://www.readbyqxmd.com/read/28286143/detection-of-crimean-congo-hemorrhagic-fever-virus-specific-igg-antibodies-in-ruminants-residing-in-central-and-western-macedonia-greece
#8
Isolde Schuster, Serafeim C Chaintoutis, Chrysostomos I Dovas, Martin H Groschup, Marc Mertens
Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne virus which causes lethal hemorrhagic fever in humans. Although, several reports regarding CCHFV antibody prevalence in humans exist in Greece, information about the current distribution is limited. The aim of the present study is to investigate the prevalence of CCHFV-specific IgG antibodies in cattle and sheep in Macedonia-Greece. The samplings were performed during spring 2013, in 5 regional units of Central Macedonia (Chalkidiki, Imathia, Kilkis, Pella and Thessaloniki) and in the 4 regional units of Western Macedonia (Grevena, Florina, Kastoria and Kozani)...
March 3, 2017: Ticks and Tick-borne Diseases
https://www.readbyqxmd.com/read/28285593/the-enzootic-life-cycle-of-borrelia-burgdorferi-sensu-lato-and-tick-borne-rickettsiae-an-epidemiological-study-on-wild-living-small-mammals-and-their-ticks-from-saxony-germany
#9
Anna Obiegala, Nina Król, Carolin Oltersdorf, Julian Nader, Martin Pfeffer
BACKGROUND: Borrelia burgdorferi (sensu lato) and rickettsiae of the spotted fever group are zoonotic tick-borne pathogens. While small mammals are confirmed reservoirs for certain Borrelia spp., little is known about the reservoirs for tick-borne rickettsiae. Between 2012 and 2014, ticks were collected from the vegetation and small mammals which were trapped in Saxony, Germany. DNA extracted from ticks and the small mammals' skin was analyzed for the presence of Rickettsia spp. and B...
March 13, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28285585/searching-for-lyme-borreliosis-in-australia-results-of-a-canine-sentinel-study
#10
Peter J Irwin, Ian D Robertson, Mark E Westman, Martine Perkins, Reinhard K Straubinger
BACKGROUND: Lyme borreliosis is a common tick-borne disease of the northern hemisphere that is caused by bacterial spirochaetes of the Borrelia burgdorferi (sensu lato) (Bbsl) complex. To date, there has been no convincing evidence for locally-acquired Lyme borreliosis on the Australian continent and there is currently a national debate concerning the nature and distributions of zoonotic tick-transmitted infectious disease in Australia. In studies conducted in Europe and the United States, dogs have been used as sentinels for tick-associated illness in people since they readily contact ticks that may harbour zoonotic pathogens...
March 13, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28284610/association-of-ehrlichia-canis-hemotropic-mycoplasma-spp-and-anaplasma-platys-and-severe-anemia-in-dogs-in-thailand
#11
Gunn Kaewmongkol, Nicha Lukkana, Sarawut Yangtara, Sarawan Kaewmongkol, Naris Thengchaisri, Theerapol Sirinarumitr, Sathaporn Jittapalapong, Stanley G Fenwick
Canine tick-borne bacteria; Ehrlichia canis, hemotropic Mycoplasma spp. and Anaplasma spp., are organisms transmitted by Rhipicephalus sanguineus ticks. However, only a few clinical studies evaluating dogs infected with these organisms and anemia condition have been published. In this study, the potential tick-borne bacteria linked to anemia were investigated in eighty-one blood samples selected from anemic dogs using a broad range nested-PCR of the 16S rRNA gene. Positive results were shown in 12/81 blood specimens (14...
March 2017: Veterinary Microbiology
https://www.readbyqxmd.com/read/28271646/two-treatment-cases-of-severe-fever-and-thrombocytopenia-syndrome-with-oral-ribavirin-and-plasma-exchange
#12
In Park, Hye In Kim, Ki Tae Kwon
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease. The primary symptoms associated with SFTS are fever, thrombocytopenia, leukopenia, nausea, and vomiting. Disease progression shows high mortality rate accompanied with multiple organ failure, bleeding tendency, and altered mentality. However, only supportive care has been the basis for the treatment of SFTS. We are reporting two patients who showed central nervous system manifestation, but cured them with ribavirin together with plasma exchange in an early state...
January 19, 2017: Infection & Chemotherapy
https://www.readbyqxmd.com/read/28270232/melting-pot-of-tick-borne-zoonoses-the-european-hedgehog-contributes-to-the-maintenance-of-various-tick-borne-diseases-in-natural-cycles-urban-and-suburban-areas
#13
Setareh Jahfari, Sanne C Ruyts, Ewa Frazer-Mendelewska, Ryanne Jaarsma, Kris Verheyen, Hein Sprong
BACKGROUND: European hedgehogs (Erinaceus europaeus) are urban dwellers and host both Ixodes ricinus and Ixodes hexagonus. These ticks transmit several zoonotic pathogens like Borrelia burgdorferi (sensu lato), Anaplasma phagocytophilum, Rickettsia helvetica, Borrelia miyamotoi and "Candidatus Neoehrlichia mikurensis". It is unclear to what extent hedgehogs in (sub) urban areas contribute to the presence of infected ticks in these areas, which subsequently pose a risk for acquiring a tick-borne disease...
March 7, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28268073/vaccinations-in-early-life-are-not-associated-with-development-of-islet-autoimmunity-in-type-1-diabetes-high-risk-children-results-from-prospective-cohort-data
#14
Andreas Beyerlein, Andreas N Strobl, Christiane Winkler, Michaela Carpus, Annette Knopff, Ewan Donnachie, Donna P Ankerst, Anette-G Ziegler
AIMS/HYPOTHESIS: Vaccinations in early childhood potentially stimulate the immune system and may thus be relevant for the pathogenesis of autoimmune diseases such as type 1 diabetes (T1D). We determined the association of vaccination burden with T1D-associated islet autoimmunity in children with high familial risk followed prospectively from birth. METHODS: A total of 20,570 certified vaccination records from 1918 children were correlated with time to onset of T1D-associated islet autoimmunity using Cox regression, considering multiple time periods up until age two years and vaccination types, and adjusting for HLA genotype, sex, delivery mode, season of birth, preterm delivery and maternal T1D status...
March 3, 2017: Vaccine
https://www.readbyqxmd.com/read/28267780/the-eurasian-otter-lutra-lutra-as-a-potential-host-for-rickettsial-pathogens-in-southern-italy
#15
Mario Santoro, Nicola D'Alessio, Anna Cerrone, Maria Gabriella Lucibelli, Giorgia Borriello, Gaetano Aloise, Clementina Auriemma, Nunzia Riccone, Giorgio Galiero
Canine monocytic ehrlichiosis and rickettsiosis are zoonotic tick-borne diseases of canids caused by the intracellular obligate bacteria Ehrlichia canis and Rickettsia species respectively. In this study, we investigated using standard and real-time PCR and sequencing, the occurrence and molecular characterization of E. canis and Rickettsia species in the Eurasian otter (Lutra lutra) from the southern Italian population. Samples were screened by using molecular assays also for Neospora caninum, Toxoplasma gondii, Clamydophyla spp...
2017: PloS One
https://www.readbyqxmd.com/read/28261565/borrelia-diversity-and-co-infection-with-other-tick-borne-pathogens-in-ticks
#16
Cristian Raileanu, Sara Moutailler, Ionuţ Pavel, Daniela Porea, Andrei D Mihalca, Gheorghe Savuta, Muriel Vayssier-Taussat
Identifying Borrelia burgdorferi as the causative agent of Lyme disease in 1981 was a watershed moment in understanding the major impact that tick-borne zoonoses can have on public health worldwide, particularly in Europe and the USA. The medical importance of tick-borne diseases has long since been acknowledged, yet little is known regarding the occurrence of emerging tick-borne pathogens such as Borrelia spp., Anaplasma phagocytophilum, Rickettsia spp., Bartonella spp., "Candidatus Neoehrlichia mikurensis", and tick-borne encephalitis virus in questing ticks in Romania, a gateway into Europe...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28261180/tick-humoral-responses-marching-to-the-beat-of-a-different-drummer
#17
REVIEW
Adela S Oliva Chávez, Dana K Shaw, Ulrike G Munderloh, Joao H F Pedra
Ticks transmit a variety of human pathogens, including Borrelia burgdorferi, the etiological agent of Lyme disease. Multiple pathogens that are transmitted simultaneously, termed "coinfections," are of increasing importance and can affect disease outcome in a host. Arthropod immunity is central to pathogen acquisition and transmission by the tick. Pattern recognition receptors recognize pathogen-associated molecular patterns and induce humoral responses through the Toll and Immune Deficiency (IMD) pathways...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28259789/evaluation-of-a-serological-test-for-the-diagnosis-of-borrelia-miyamotoi-disease-in-europe
#18
Setareh Jahfari, Denis S Sarksyan, Nadezda M Kolyasnikova, Joppe W Hovius, Hein Sprong, Alexander E Platonov
BACKGROUND: Borrelia miyamotoi causes systemic febrile illness and is transmitted by the same tick species that transmits Borrelia burgdorferi sensu lato and tick-borne encephalitis virus. We describe a serological test using a fragment of glycerophosphodiester phosphodiesterase (GlpQ) as an antigen, and determined its performance in well-defined patient categories. METHODS: Serum of patients with PCR-confirmed Borrelia miyamotoi disease (BMD), Lyme borreliosis (LB), tick-borne encephalitis (TBE), and healthy blood donors (HBD) were collected in Udmurt Republic, Russia...
March 1, 2017: Journal of Microbiological Methods
https://www.readbyqxmd.com/read/28259724/current-status-of-crimean-congo-hemorrhagic-fever-in-who-eastern-mediterranean-region-issues-challenges-and-future-directions
#19
REVIEW
Seif S Al-Abri, Idris Al Abaidani, Mehdi Fazlalipour, Ehsan Mostafavi, Hakan Leblebicioglu, Natalia Pshenichnaya, Ziad A Memishemish, Roger Hewson, Jorgen Eskild Petersen, Peter Mala, Tran Minh Nhu Nguyen, Mamunur Rahman Malik, Pierre Formenty, Rosanna Lucy Jeffries
Crimean-Congo hemorrhagic fever (CCHF) is the most wide-spread, tick-borne viral disease affecting humans. The disease is endemic in many regions such as Africa, Asia, Eastern and Southern Europe, and Central Asia. Recently, the incidence of CCHF has increased rapidly in the countries of the Eastern Mediterranean Region of the World Health Organization (WHO), with sporadic human cases and outbreaks of CCHF being reported from a number of countries in the region. Despite the rapidly growing incidence of the disease, there is currently no accurate data on the burden of the disease in the region due to different surveillance systems for CCHF in the countries...
March 1, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/28257433/a-comparison-of-nonlinear-mixed-models-and-response-to-selection-of-tick-infestation-on-lambs
#20
Panya Sae-Lim, Lise Grøva, Ingrid Olesen, Luis Varona
Tick-borne fever (TBF) is stated as one of the main disease challenges in Norwegian sheep farming during the grazing season. TBF is caused by the bacterium Anaplasma phagocytophilum that is transmitted by the tick Ixodes ricinus. A sustainable strategy to control tick-infestation is to breed for genetically robust animals. In order to use selection to genetically improve traits we need reliable estimates of genetic parameters. The standard procedures for estimating variance components assume a Gaussian distribution of the data...
2017: PloS One
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