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Seasonal rhinitis

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https://www.readbyqxmd.com/read/29033449/symptomatology-patterns-in-children-with-allergic-rhinitis
#1
Michael Katotomichelakis, Theodoros Iliou, Ioannis Karvelis, Evangelos Giotakis, Gerasimos Daniilides, Eleni Erkotidou, Christos Lazaridis, George K Anastassopoulos
BACKGROUND Although allergic rhinitis (AR) is recognized as a growing global health disease with considerable importance for patients' lives, especially among children and adolescents, there is a lack of population studies concerning symptomatology patterns of the disease. The present study aimed to explore symptoms prevalence among school-aged children, to detect any correlation between allergen sensitivities with symptomatology patterns, and, finally, to evaluate the association of the sensitivity grade score with symptoms severity or seasonality...
October 16, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/29022537/respiratory-comorbidity-in-south-african-children-with-atopic-dermatitis
#2
C L Gray, M E Levin, G Du Toit
BACKGROUND: Atopic dermatitis (AD) is an early and important step in the propagation of the allergic march, enhancing food and respiratory allergies via epicutaneous sensitisation to allergens. OBJECTIVES: To determine the prevalence and patterns of aeroallergen sensitisation, asthma and allergic rhinitis in South African (SA) children with AD. METHODS: This was a prospective, observational study in a paediatric university hospital in Cape Town, SA...
September 22, 2017: South African Medical Journal, Suid-Afrikaanse Tydskrif Vir Geneeskunde
https://www.readbyqxmd.com/read/29022093/-seasonal-allergic-conjunctivitis
#3
K Schröder, D Finis, S Meller, M Wagenmann, G Geerling, U Pleyer
Seasonal allergic conjunctivitis (SAC) is a frequent disease, which is often associated with allergic rhinitis and subsequently manifested as allergic rhinoconjunctivitis. In contrast to other types of chronic allergic conjunctivitis, the course of SAC is not sight-threatening. Pathogenetically, the underlying cause of SAC is an immunoglobulin E (IgE) mediated, Th2-driven type 1 hypersensitivity reaction. Clinically it presents with itching, light-red conjunctival injection as well as chemosis that exceeds the extent of conjunctival injection...
October 11, 2017: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/28990893/-pollen-food-allergy-syndrome
#4
Özlem Kar Kurt, Mustafa Erkoçoğlu, Mevlüt Kurt
Pollen food allergy syndrome, is a type I cross-reaction mediated by IgE antibodies between an aeroallergen and a plant-derived antigen. Main symptoms are typically consist of localized oral symptoms such as numbness of the lip or mouth, itching, tingling and swelling of lips, tongue, palate and pharynx without systemic symptoms. Patients with seasonal allergic rhinitis, asthma or both more frequently experience pollen food allergy syndrome. Because most patients have mild symptoms and the improvement by avoiding food, the true incidence is unknown...
June 2017: Tüberküloz Ve Toraks
https://www.readbyqxmd.com/read/28958744/very-poorly-controlled-asthma-in-urban-minority-children-lessons-learned
#5
Arlene M Butz, Melissa Bellin, Mona Tsoukleris, Shawna S Mudd, Joan Kub, Jean Ogborn, Tricia Morphew, Cassia Lewis-Land, Mary Elizabeth Bollinger
BACKGROUND: Very poorly controlled (VPC) asthma in children is associated with ongoing acute exacerbations but factors associated with VPC are understudied. OBJECTIVE: To examine the risk factors associated with VPC asthma in urban minority children. METHODS: This descriptive study examined asthma control levels (well-controlled [WC], not well-controlled [NWC], and VPC) at baseline and 6 months in children participating in an ongoing randomized controlled trial of an emergency department/home environmental control intervention...
September 22, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28932345/the-grass-pollen-season-2015-a-proof-of-concept-multi-approach-study-in-three-different-european-cities
#6
Maximilian Kmenta, Katharina Bastl, Uwe Berger, Matthias F Kramer, Matthew D Heath, Sanna Pätsi, Anna-Mari Pessi, Annika Saarto, Barbora Werchan, Matthias Werchan, Reinhard Zetter, Karl-Christian Bergmann
BACKGROUND: Grasses release the most widespread aeroallergens with considerable sensitization rates, while different species produce several pollen concentration peaks throughout the season. This study analyzed the prevalence of grass species in three different European city areas and compared the flowering period of these species with daily pollen concentrations and the symptom loads of grass pollen allergy sufferers. METHODS: The most prevalent grass species in Vienna (Austria), Berlin (Germany) and Turku (Finland) were studied and examined by use of three different approaches: phenology, pollen monitoring and symptom load evaluation...
2017: World Allergy Organization Journal
https://www.readbyqxmd.com/read/28929717/-thunderstorm-and-asthma-outbreaks-during-pollen-season
#7
Maria D'Amato, Isabella Annesi-Maesano, Antonio Molino, Mauro Mormile, Carolina Vitale, Alessandro Vatrella, Alessandro Sanduzzi, Gennaro D'Amato
An increasing body of evidence shows the occurrence of asthma epidemics, sometimes also severe, during thunderstorms in the pollen season in various geographical zones. The main hypothesis explaining association between thunderstorms and asthma claims that thunderstorms can concentrate pollen grains at ground level; these grains may then release allergenic particles of respirable size in the atmosphere after their rupture by osmotic shock. During the first 20-30 minutes of a thunderstorm, patients suffering from pollen allergy may inhale a high concentration of the allergenic material dispersed into the atmosphere, which can, in turn, induce asthmatic reactions, often severe...
May 2017: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/28928804/efficacy-of-a-leukotriene-receptor-antagonist-for-pediatric-cedar-pollen-allergy-complicated-by-asthma
#8
Shigemi Yoshihara, Yutaka Kikuchi, Mari Saitou, Susumu Yanagawa, Noriko Kanno, Hiroshi Igarashi, Hironobu Fukuda, Akiko Iimura, Toshio Abe, Yumi Yamada, Tamotsu Andou, Osamu Arisaka
Leukotriene receptor antagonists (LTRAs) are identified as a monotherapy for asthma and allergic rhinitis; however, their use in children for treatment of these diseases has not been examined. Accordingly, the present study investigated the efficacy of pranlukast dry syrup for children with both pollinosis and asthma. The subjects were children receiving treatment for asthma who were also diagnosed with cedar pollen allergy. Patients were divided into a group that received continuous treatment with pranlukast (group A; n=20) and a group that commenced add-on treatment for pollinosis following the onset of symptoms (group B; n=20)...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28919832/seasonal-patterns-of-oral-antihistamine-and-intranasal-corticosteroid-purchases-from-australian-community-pharmacies-a-retrospective-observational-study
#9
A Simon Carney, David B Price, Pete K Smith, Richard Harvey, Vicky Kritikos, Sinthia Z Bosnic-Anticevich, Louise Christian, Derek A Skinner, Victoria Carter, Alice Ms Durieux
PURPOSE: To explore patterns in the purchase of prescription and over-the-counter (OTC) oral antihistamines (OAHs) and intranasal corticosteroids (INCSs) by patients, from pharmacies in different geographical regions of Australia. PATIENTS AND METHODS: Retrospective observational study using a database containing anonymous pharmacy transaction data from 20.0% of the pharmacies in Australia that link doctor prescriptions and OTC information. Pharmacy purchases of at least one prescription or OTC rhinitis treatment during 2013 and 2014 were assessed...
2017: Pragmatic and Observational Research
https://www.readbyqxmd.com/read/28857184/pathogenicity-of-memory-th2-cells-is-linked-to-stage-of-allergic-rhinitis
#10
T Iinuma, Y Okamoto, Y Morimoto, T Arai, T Sakurai, S Yonekura, D Sakurai, K Hirahara, T Nakayama
BACKGROUND: Allergic rhinitis (AR) consists of three developmental stages that are based on the presence/absence of antigen-specific IgE and symptoms. The pathogenic Th2 (Tpath2) cells constitute a population of Th2 cells with additional potentially pathogenic characteristics. We examined the relationship between Tpath2 cells and the stages of allergic rhinitis by focusing on ST2, which is an IL-33 receptor. METHODS: Patients with Japanese cedar pollen-induced AR (JCP-AR) and healthy volunteers were divided into "nonsensitized," "asymptomatic sensitized (AS)," and "JCP-AR" groups...
August 30, 2017: Allergy
https://www.readbyqxmd.com/read/28831847/how-to-use-a-corticosteroid-nasal-spray
#11
Janette Bartle
Rationale and key points This article outlines the appropriate and effective technique for using a corticosteroid nasal spray. If these sprays are used inappropriately, they will be ineffective and might reduce the patient's adherence to the treatment. Nurses can use the information in this article to advise patients on the appropriate technique for using a corticosteroid nasal spray. » Topical corticosteroid nasal sprays are commonly used to treat seasonal and persistent allergic rhinitis, which cause inflammation inside the nose and can lead to nasal blockage...
August 23, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28831678/evaluation-of-allergic-sensitization-in-lebanese-patients-with-allergic-conjunctivitis
#12
Nicolas Arej, Carla Irani, Youssef Abdelmassih, Elise Slim, Joelle Antoun, Riad Bejjani, Alexandre Schakal, Naji Waked
PURPOSE: To describe the profile of patients with allergic conjunctivitis (AC) regarding their demographics, symptomatology and specific allergen sensitization, in a Lebanese tertiary hospital. METHODS: Cross-sectional study conducted at the Hôtel-Dieu de France hospital (Beirut, Lebanon) during a period of 18 months. Patients with seasonal or perennial AC presenting for ophthalmic consultation had measurements of total and specific IgE. A matching group of patients with AC seen at the allergist office during the same period underwent skin prick tests (SPTs)...
August 22, 2017: International Ophthalmology
https://www.readbyqxmd.com/read/28814941/a-survey-on-the-perception-of-allergy-specialists-about-the-reimbursed-grass-pollen-tablets-for-seasonal-allergic-rhinitis-in-italy
#13
Ilaria Massaro, Oliviero Rossi, Cristoforo Incorvaia, Carlo Lombardi
BACKGROUND: Sublingual immunotherapy (SLIT) is a feasible option to classical subcutaneous immunotherapy to treat respiratory allergy and is increasingly prescribed in Europe. However, the lack of reimbursement may limit its prescription. In 2015, the 5-grass pollen tablets was authorized by the European Medicine Agency to treat grass-pollen induced rhinitis and was approved in Italy for full reimbursement. We evaluated the opinions of allergy specialists after the availability of the reimbursed 5-grass pollen tablets...
2017: Clinical and Molecular Allergy: CMA
https://www.readbyqxmd.com/read/28803150/residential-greenness-and-allergic-respiratory-diseases-in-children-and-adolescents-a-systematic-review-and-meta-analysis
#14
REVIEW
K A Lambert, G Bowatte, R Tham, C Lodge, L Prendergast, J Heinrich, M J Abramson, S C Dharmage, B Erbas
BACKGROUND: The aetiology of allergic respiratory disease in children is not yet fully understood. Environmental factors are believed to play a major part. The amount of green vegetation surrounding the home (residential greenness) has been recently identified as a potentially important exposure OBJECTIVES: Our goal was to provide a systematic review and quantitative summary of the evidence regarding the relationship between residential greenness and allergic respiratory diseases in children...
November 2017: Environmental Research
https://www.readbyqxmd.com/read/28760534/an-analysis-of-factors-related-to-the-effect-of-sublingual-immunotherapy-on-japanese-cedar-pollen-induced-allergic-rhinitis
#15
Syuji Yonekura, Yoshitaka Okamoto, Daiju Sakurai, Kimihiro Okubo, Minoru Gotoh, Shinya Kaneko, Akiyoshi Konno
BACKGROUND: Sublingual immunotherapy (SLIT) can improve the symptoms of allergic rhinitis and modify its natural history; however, its efficacy varies among patients. This study aimed to determine which factors modify the effect of SLIT through post hoc analysis of a previous phase 3 trial of standardized Japanese cedar (JC) pollen extract (CEDARTOLEN(®)). METHODS: The study included 482 patients who had previously completed a phase 3 trial during two seasons. The SLIT and placebo groups each contained 241 subjects...
July 28, 2017: Allergology International: Official Journal of the Japanese Society of Allergology
https://www.readbyqxmd.com/read/28705451/nasal-carbon-dioxide-used-as-needed-in-the-symptomatic-treatment-of-seasonal-allergic-rhinitis
#16
Thomas B Casale, Robert F Onder, Robert B Berkowitz, Phillip E Korenblat
BACKGROUND: Nasal, noninhaled carbon dioxide (CO2) was shown to be effective for the treatment of symptoms of seasonal allergic rhinitis (SAR) and perennial allergic rhinitis in single application studies. OBJECTIVE: To assess the efficacy of as-needed treatment with nasal, noninhaled CO2 in patients with SAR. METHODS: Fifty-six ragweed-allergic patients were enrolled at 3 sites in this study. After a 3- to 7-day run-in, 32 eligible patients who had an instantaneous total nasal symptom score of 8 or more out of a maximum of 12 in at least 2 SAR episodes per day were randomized to the CO2 group (n = 19) or to the placebo group (n = 13)...
July 11, 2017: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/28681506/safety-and-pharmacodynamics-of-intranasal-gsk2245035-a-tlr7-agonist-for-allergic-rhinitis-a-randomized-trial
#17
A K Ellis, D C Tsitoura, D Quint, W Powley, L A Lee
BACKGROUND: Toll-like receptor 7 (TLR7) stimulation in the airways may reduce responses to aeroallergens by induction of type 1 interferons (IFNs). GSK2245035 is a novel selective TLR7 agonist in pharmaceutical development. OBJECTIVE: Assessment of safety, pharmacodynamics and nasal allergic reactivity following repeated weekly intranasal (i.n.) GSK2245035. METHODS: This randomized, double-blind, placebo-controlled study (TL7116958) was conducted over two pollen seasons (2013-2014) and follow-up study (204509) conducted 1 year later...
July 5, 2017: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28675499/ultra-short-course-booster-is-effective-in-recurrent-grass-pollen-induced-allergic-rhinitis
#18
O Pfaar, S Lang, U Pieper-Fürst, A Astvatsatourov, F Gerich, L Klimek, M F Kramer, Y Reydelet, K Shah-Hosseini, R Mösges
BACKGROUND: A relevant proportion of allergic rhinitis (AR) patients experience recurrent symptoms after successfully completing allergen immunotherapy (AIT). This prospective, controlled, non-interventional study used internationally standardised instruments to determine the clinical effects of a preseasonal, ultra-short-course booster AIT on clinical outcome parameters. METHODS: This two-arm study included patients aged ≥12 years with recurrent grass pollen-induced seasonal AR who had completed a successful course of any grass pollen AIT at least five years before enrolment...
July 4, 2017: Allergy
https://www.readbyqxmd.com/read/28658067/seasonal-allergic-rhinitis-a-focused-systematic-review-and-practice-parameter-update
#19
Dana V Wallace, Mark S Dykewicz
PURPOSE OF REVIEW: The review compares and contrasts seven major United States and international allergic rhinitis guidelines from 2008 to 2017. RECENT FINDINGS: Despite many treatment options for allergic rhinitis, patients often report lack of therapeutic control and a reduced quality of life. Guidelines intended to improve allergic rhinitis care have been evolving into evidence based, systematic reviews, with less reliance on consensus of expert opinion characteristic of more traditional guidelines...
August 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28633877/epithelial-proteome-profiling-suggests-essential-role-of-interferon-inducible-proteins-in-allergic-rhinitis
#20
Joseph Ndika, Liisa Airaksinen, Hille Suojalehto, Piia Karisola, Nanna Fyhrquist, Anne Puustinen, Harri Alenius
BACKGROUND: Seasonal allergic rhinitis (SAR) as a result of intermittent exposure to seasonal pollen, causes itching, nasal congestion and repeated sneezing, with profound effects on the quality of life, work productivity and school performance. While both the genotype and environmental factors may contribute to the immunological basis of allergic reactions, the molecular underpinnings associated with the pathogenesis of allergic rhinitis are not entirely clear. METHODS: To address these questions, nasal epithelial brushings were collected from 29 SAR and 31 Control individuals during and after the pollen season...
June 17, 2017: Journal of Allergy and Clinical Immunology
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