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Malaria surveillance

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https://www.readbyqxmd.com/read/29037242/malaria-risk-factors-and-care-seeking-behaviour-within-the-private-sector-among-high-risk-populations-in-vietnam-a-qualitative-study
#1
Ingrid Chen, Huong Ngo Thi Thanh, Andrew Lover, Phung Thi Thao, Tang Viet Luu, Hoang Nghia Thang, Ngo Duc Thang, Josselyn Neukom, Adam Bennett
BACKGROUND: Vietnam has successfully reduced malaria incidence by more than 90% over the past 10 years, and is now preparing for malaria elimination. However, the remaining malaria burden resides in individuals that are hardest to reach, in highly remote areas, where many malaria cases are treated through the informal private sector and are not reported to public health systems. This qualitative study aimed to contextualize and characterize the role of private providers, care-seeking behaviour of individuals at high risk of malaria, as well as risk factors that should be addressed through malaria elimination programmes in Vietnam...
October 16, 2017: Malaria Journal
https://www.readbyqxmd.com/read/29037193/molecular-surveillance-of-pfhrp2-and-pfhrp3-deletions-in-plasmodium-falciparum-isolates-from-mozambique
#2
Himanshu Gupta, Gloria Matambisso, Beatriz Galatas, Pau Cisteró, Lidia Nhamussua, Wilson Simone, Jane Cunningham, N Regina Rabinovitch, Pedro Alonso, Franciso Saute, Pedro Aide, Alfredo Mayor
BACKGROUND: Malaria programmes use Plasmodium falciparum histidine-rich protein-2 (PfHRP2) based rapid diagnostic tests (RDTs) for malaria diagnosis. The deletion of this target antigen could potentially lead to misdiagnosis, delayed treatment and continuation of active transmission. METHODS: Plasmodium falciparum isolates (n = 1162) collected in Southern Mozambique were assessed by RDTs, microscopy and/or 18SrRNA qPCR. pfhrp2 and pfhrp3 deletions were investigated in isolates from individuals who were negative by RDT but positive by microscopy and/or qPCR (n = 69) using gene-specific PCRs, with kelch13 PCR as the parasite DNA control...
October 16, 2017: Malaria Journal
https://www.readbyqxmd.com/read/29034229/spatiotemporal-modeling-for-fine-scale-maps-of-regional-malaria-endemicity-and-its-implications-for-transitional-complexities-in-a-routine-surveillance-network-in-western-cambodia
#3
Suguru Okami, Naohiko Kohtake
Due to the associated and substantial efforts of many stakeholders involved in malaria containment, the disease burden of malaria has dramatically decreased in many malaria-endemic countries in recent years. Some decades after the past efforts of the global malaria eradication program, malaria elimination has again featured on the global health agenda. While risk distribution modeling and a mapping approach are effective tools to assist with the efficient allocation of limited health-care resources, these methods need some adjustment and reexamination in accordance with changes occurring in relation to malaria elimination...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/29031286/surveillance-of-vector-borne-infections-chikungunya-dengue-and-malaria-in-bo-sierra-leone-2012-2013
#4
Donald F Dariano, Chris R Taitt, Kathryn H Jacobsen, Umaru Bangura, Alfred S Bockarie, Moses J Bockarie, Joseph Lahai, Joseph M Lamin, Tomasz A Leski, Chadwick Yasuda, David A Stenger, Rashid Ansumana
Malaria remains a significant cause of morbidity and mortality in West Africa, but the contribution of other vector-borne infections (VBIs) to the burden of disease has been understudied. We used rapid diagnostic tests (RDTs) for three VBIs to test blood samples from 1,795 febrile residents of Bo City, Sierra Leone, over a 1-year period in 2012-2013. In total, 24% of the tests were positive for malaria, fewer than 5% were positive for markers of dengue virus infection, and 39% were positive for IgM directed against chikungunya virus (CHIKV) or a related alphavirus...
October 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29029609/modelling-the-implications-of-stopping-vector-control-for-malaria-control-and-elimination
#5
Joshua O Yukich, Nakul Chitnis
BACKGROUND: Increasing coverage of malaria vector control interventions globally has led to significant reductions in disease burden. However due to its high recurrent cost, there is a need to determine if and when vector control can be safely scaled back after transmission has been reduced. METHODS AND FINDINGS: A mathematical model of Plasmodium falciparum malaria epidemiology was simulated to determine the impact of scaling back vector control on transmission and disease...
October 13, 2017: Malaria Journal
https://www.readbyqxmd.com/read/29018840/sharing-individual-patient-and-parasite-level-data-through-the-worldwide-antimalarial-resistance-network-platform-a-qualitative-case-study
#6
Elizabeth Pisani, Stella Botchway
BACKGROUND: Increasingly, biomedical researchers are encouraged or required by research funders and journals to share their data, but there's very little guidance on how to do that equitably and usefully, especially in resource-constrained settings. We performed an in-depth case study of one data sharing pioneer: the WorldWide Antimalarial Resistance Network (WWARN). METHODS: The case study included a records review, a quantitative analysis of WAARN-related publications, in-depth interviews with 47 people familiar with WWARN, and a witness seminar involving a sub-set of 11 interviewees...
2017: Wellcome Open Research
https://www.readbyqxmd.com/read/29016343/passively-versus-actively-detected-malaria-similar-genetic-diversity-but-different-complexity-of-infection
#7
Zuleima Pava, Irene Handayuni, Leily Trianty, Retno A S Utami, Yusrifar K Tirta, Agatha M Puspitasari, Faustina Burdam, Enny Kenangalem, Grennady Wirjanata, Steven Kho, Hidayat Trimarsanto, Nicholas Anstey, Jeanne Rini Poespoprodjo, Rintis Noviyanti, Ric N Price, Jutta Marfurt, Sarah Auburn
The surveillance of malaria is generally undertaken on the assumption that samples passively collected at health facilities are comparable to or representative of the broader Plasmodium reservoir circulating in the community. Further characterization and comparability of the hidden asymptomatic parasite reservoir are needed to inform on the potential impact of sampling bias. This study explores the impact of sampling strategy on molecular surveillance by comparing the genetic make-up of Plasmodium falciparum and Plasmodium vivax isolates collected by passive versus active case detection...
September 5, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29016341/prevalence-of-clinical-and-subclinical-plasmodium-falciparum-and-plasmodium-vivax-malaria-in-two-remote-rural-communities-on-the-china-myanmar-border
#8
Fang Huang, Shannon Takala-Harrison, Hui Liu, Jian-Wei Xu, Heng-Lin Yang, Matthew Adams, Biraj Shrestha, Gillian Mbambo, Demian Rybock, Shui-Sen Zhou, Zhi-Gui Xia, Xiao-Nong Zhou, Christopher V Plowe, Myaing M Nyunt
Malaria infections may be symptomatic, leading to treatment, or "asymptomatic," typically detected through active surveillance, and not leading to treatment. Malaria elimination may require purging both types of infection. Using detection methods with different sensitivities, we conducted a cross-sectional study in two rural communities located along the border between China's Yunnan Province and Myanmar's Shan and Kachin States, to estimate the prevalence of asymptomatic and symptomatic malaria. In Mong Pawk, all infections detected were asymptomatic, and the prevalence of Plasmodium falciparum was 0...
September 5, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28991406/burden-of-influenza-among-hospitalized-febrile-children-in-ghana
#9
Benedikt Hogan, Luise Ammer, Marlow Zimmermann, Tabea Binger, Ralf Krumkamp, Nimako Sarpong, Theresa Rettig, Denise Dekker, Benno Kreuels, Lisa Reigl, Kennedy Gyau Boahen, Charity Wiafe, Yaw Adu-Sarkodie, Ellis Owusu-Dabo, Jürgen May, Daniel Eibach
BACKGROUND: Influenza surveillance data from Africa indicate a substantial disease burden with high mortality. However local influenza data from district hospitals with limited laboratory facilities are still scarce. OBJECTIVES: To identify the frequency and seasonal distribution of influenza among hospitalized febrile children in a rural hospital in Ghana and to describe differential diagnoses to other severe febrile infections. METHODS: Between January 2014 and April 2015 all children with a temperature of ≥38°C admitted to a district hospital in Ghana were screened for influenza A and B by RT-PCR and differentiated to subtypes A(H1N1)pdm09 and A(H3N2)...
October 9, 2017: Influenza and Other Respiratory Viruses
https://www.readbyqxmd.com/read/28982374/relationships-between-infection-with-plasmodium-falciparum-during-pregnancy-measures-of-placental-malaria-and-adverse-birth-outcomes
#10
James Kapisi, Abel Kakuru, Prasanna Jagannathan, Mary K Muhindo, Paul Natureeba, Patricia Awori, Miriam Nakalembe, Richard Ssekitoleko, Peter Olwoch, John Ategeka, Patience Nayebare, Tamara D Clark, Gabrielle Rizzuto, Atis Muehlenbachs, Diane V Havlir, Moses R Kamya, Grant Dorsey, Stephanie L Gaw
BACKGROUND: Malaria in pregnancy has been associated with maternal morbidity, placental malaria, and adverse birth outcomes. However, data are limited on the relationships between longitudinal measures of malaria during pregnancy, measures of placental malaria, and birth outcomes. METHODS: This is a nested observational study of data from a randomized controlled trial of intermittent preventive therapy during pregnancy among 282 participants with assessment of placental malaria and delivery outcomes...
October 5, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28982133/simultaneous-assessment-of-iodine-iron-vitamin-a-malarial-antigenemia-and-inflammation-status-biomarkers-via-a-multiplex-immunoassay-method-on-a-population-of-pregnant-women-from-niger
#11
Eleanor Brindle, Lorraine Lillis, Rebecca Barney, Sonja Y Hess, K Ryan Wessells, Césaire T Ouédraogo, Sara Stinca, Michael Kalnoky, Roger Peck, Abby Tyler, Christopher Lyman, David S Boyle
Deficiencies of vitamin A, iron, and iodine are major public health concerns in many low- and middle-income countries, but information on their status in populations is often lacking due to high costs and logistical challenges associated with assessing micronutrient status. Accurate, user-friendly, and low-cost analytical tools are needed to allow large-scale population surveys on micronutrient status. We present the expansion of a 7-plex protein microarray tool for the simultaneous measurement of up to seven biomarkers with relevance to the assessment of the key micronutrients iron, iodine, and vitamin A, and inflammation and malaria biomarkers: α-1-acid glycoprotein, C-reactive protein, ferritin, retinol binding protein 4, soluble transferrin receptor, thyroglobulin, and histidine-rich protein II...
2017: PloS One
https://www.readbyqxmd.com/read/28979647/the-who-global-reference-list-of-100-core-health-indicators-the-example-of-sierra-leone
#12
Reinhard Kaiser, Natalie Johnson, Mohamed Falilu Jalloh, Foday Dafae, John Terrell Redd, Sara Hersey, Amara Jambai
The global reference list of 100 core health indicators is a standard set of indicators published by the World Health Organization in 2015. We reviewed core health indicators in the public domain and in-country for Sierra Leone, the African continent and globally. Review objectives included assessing available sources, accessibility and feasibility of obtaining data and informing efforts to monitor program progress. Our search strategy was guided by feasibility considerations targeting mainly national household surveys in Sierra Leone and topic-specific and health statistics reports published annually by WHO...
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28979353/malaria-outbreak-investigation-in-chipinge-zimbabwe-a-case-control-study
#13
Tinashe Kureya, Augustine Ndaimani, Maxwell Mhlanga
BACKGROUND: Malaria outbreaks are common in Zimbabwe. They are common in Manicaland, which has the greatest burden of malaria in the country. METHODS: A matched case control study was conducted to investigate the malaria outbreak in ward 13 and 14 of Chipinge district in Manicaland Province in Zimbabwe, week 30 to week 40 of year 2015. A sample size of 92 (46 cases and 46 controls) was used. Guided interviews were conducted with the aid of a structured questionnaire and a checklist...
July 2017: Iranian Journal of Parasitology
https://www.readbyqxmd.com/read/28973483/declining-malaria-transmission-differentially-impacts-on-the-maintenance-of-humoral-immunity-to-plasmodium-falciparum-in-children
#14
Cleopatra K Mugyenyi, Salenna R Elliott, Xi Zen Yap, Gaoqian Feng, Philippe Boeuf, Gregory Fegan, Faith F H Osier, Freya J I Fowkes, Marion Avril, Thomas N Williams, Kevin Marsh, James G Beeson
BACKGROUND: We investigated the poorly understood impact of declining malaria transmission on maintenance of antibodies to P. falciparum merozoite antigens and infected erythrocytes (IEs), including functional immunity. METHODS: In a 3-year longitudinal cohort of 300 Kenyan children, antibodies to different merozoite AMA1 and MSP2 alleles, IE surface antigens, and antibody functional activities were quantified. RESULTS: Over a period in which malaria transmission declined markedly, AMA1 and MSP2 antibodies decreased substantially; estimated half-lives of antibody duration were 0...
August 2, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28968846/population-dynamics-and-plasmodium-falciparum-haemosporida-plasmodiidae-infectivity-rates-for-the-malaria-vector-anopheles-arabiensis-diptera-culicidae-at-mamfene-kwazulu-natal-south-africa
#15
Leonard C Dandalo, Basil D Brooke, Givemore Munhenga, Leanne N Lobb, Jabulani Zikhali, Sifiso P Ngxongo, Phineas M Zikhali, Sipho Msimang, Oliver R Wood, Mohlominyana Mofokeng, Eunice Misiani, Tobias Chirwa, Lizette L Koekemoer
Anopheles arabiensis (Patton; Diptera: Culicidae) is a major malaria vector in the southern African region. In South Africa, effective control of this species using indoor-based interventions is reduced owing to its tendency to rest outdoors. As South Africa moves towards malaria elimination there is a need for complementary vector control strategies. One of the methods under consideration is the use of the sterile insect technique (SIT). Key to the successful implementation of an SIT programme is prior knowledge of the size and spatial distribution of the target population...
September 6, 2017: Journal of Medical Entomology
https://www.readbyqxmd.com/read/28965490/study-roadmap-for-high-throughput-development-of-easy-to-use-and-affordable-biomarkers-as-diagnostics-for-tropical-diseases-a-focus-on-malaria-and-schistosomiasis
#16
Kokouvi Kassegne, Ting Zhang, Shen-Bo Chen, Bin Xu, Zhi-Sheng Dang, Wang-Ping Deng, Eniola Michael Abe, Hai-Mo Shen, Wei Hu, Takele Geressu Guyo, Solomon Nwaka, Jun-Hu Chen, Xiao-Nong Zhou
BACKGROUND: Interventions are currently being used against 'infectious diseases of poverty', which remain highly debilitating and deadly in most endemic countries, especially malaria, schistosomiasis, echinococcosis and African sleeping sickness. However, major limitations of current 'traditional' methods for diagnosis are neither simple nor convenient for population surveillance, and showed low sensitivity and specificity. Access to novel technologies for the development of adequate and reliable tools are expressly needed...
October 2, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28962622/malaria-case-management-by-community-health-workers-in-the-central-african-republic-from-2009-2014-overcoming-challenges-of-access-and-instability-due-to-conflict
#17
Laura Ruckstuhl, Christian Lengeler, Jean Méthode Moyen, Helle Garro, Richard Allan
BACKGROUND: In the Central African Republic (CAR), decades of armed conflict have crippled the public health system. This has left the population without timely access to life-saving services and therefore vulnerable to the numerous consequences of infectious diseases, including malaria. As a response, in 2008 an international non-governmental organization started a network of community health workers (CHWs) in the highly malaria-endemic region of northwest CAR. The area has experienced years of violent clashes between rebel groups and seen hundreds of thousands of people displaced...
September 29, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28931134/risk-activities-and-pre-travel-health-seeking-practices-of-notified-cases-of-imported-infectious-diseases-in-australia
#18
Prakash Paudel, C Raina, Nicholas Zwar, Holly Seale, Heather Worth, Mohamud Sheikh, Anita E Heywood
Background: Travellers are at risk of acquiring infectious diseases during travel, with risks differing by destination, travel and traveller characteristics. A pre-travel health consultation may minimize this risk. However, uptake of pre-travel health advice remains low. We investigated pre-travel health preparations and disease-specific risk behaviours among notified cases of selected travel-associated infectious diseases imported into Australia. Methods: Prospective enhanced surveillance of notified cases of typhoid, paratyphoid, measles, hepatitis A, hepatitis E, malaria and chikungunya was conducted in two Australian states between February 2013 and January 2014...
September 1, 2017: Journal of Travel Medicine
https://www.readbyqxmd.com/read/28927422/proximity-to-vector-breeding-site-and-risk-of-plasmodium-vivax-infection-a-prospective-cohort-study-in-rural-ethiopia
#19
Alexander Nissen, Jackie Cook, Eskindir Loha, Bernt Lindtjørn
BACKGROUND: Despite falling incidence and mortality since the turn of the century, malaria remains an important global health challenge. In the future fight against malaria, greater emphasis will have to be placed on understanding and addressing malaria caused by the Plasmodium vivax parasite. Unfortunately, due to years of neglect and underfunding, there are currently many gaps in knowledge of P. vivax malaria. The aims of the present study were to explore the association between distance to vector breeding site and P...
September 19, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28925418/mhealth-application-areas-and-technology-combinations-a-comparison-of-literature-from-high-and-low-middle-income-countries
#20
Haitham Abaza, Michael Marschollek
BACKGROUND: With the continuous and enormous spread of mobile technologies, mHealth has evolved as a new subfield of eHealth. While eHealth is broadly focused on information and communication technologies, mHealth seeks to explore more into mobile devices and wireless communication. Since mobile phone penetration has exceeded other infrastructure in low and middle-income countries (LMICs), mHealth is seen as a promising component to provide pervasive and patient-centered care. OBJECTIVES: The aim of our research work for this paper is to examine the mHealth literature to identify application areas, target diseases, and mHealth service and technology types that are most appropriate for LMICs...
August 8, 2017: Methods of Information in Medicine
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