keyword
https://read.qxmd.com/read/37534050/clinical-and-management-dilemmas-concerning-early-stage-cervical-cancer-in-pregnancy-a-case-report
#21
Andi Kurniadi, Dani Setiawan, Jessica Kireina, Dodi Suardi, Siti Salima, Febia Erfiandi, Mia Yasmina Andarini
BACKGROUND: Cervical cancer in pregnancy is rare and its management remains a formidable challenge. Clinical upstaging is a serious concern. Presentation may mimic pregnancy-related conditions, thus delaying diagnosis and leading to an advanced stage at presentation. In addition, concerns regarding chemotherapy safety in pregnancy may hinder its administration. Definitive therapy may also be delayed due to pregnancy. CASE REPORT: A 37-year-old G3P2A0 10-11 weeks pregnant woman was diagnosed with stage IB2 cervical cancer...
2023: International Journal of Women's Health
https://read.qxmd.com/read/37422370/fallopian-tube-cytology-as-a-diagnostic-tool-for-adnexal-malignancy-the-cytosalps-score
#22
JOURNAL ARTICLE
Victoria Psomiadou, Sofia Lekka, Theodoros Panoskaltsis, Helen Tsouma, Natasa Novkovic, Helen J Trihia, Olympia Tzaida, Dimitrios Korfias, Panagiotis Giannakas, Christos Iavazzo, Christos Papadimitriou, Nikolaos Vlahos, George Vorgias
INTRODUCTION: During the past decade, the theory that high-grade extrauterine pelvic tumors originate from the fallopian tube has been strongly suggested. Our study aims to illuminate the possible role of tubal cytology as an accessory identification tool for gynecologic extrauterine malignancies, allowing in the long term the implementation of population-level cytologic tube evaluation during all benign gynecologic surgeries that do not result in salpingectomy. MATERIALS AND METHODS: We ex vivo collect salpingeal epithelial cells from the fibria directly from fresh fallopian tube specimens from women undergoing salpingectomy for any indication...
May 23, 2023: Journal of the American Society of Cytopathology
https://read.qxmd.com/read/37261821/salpingectomy-in-ovarian-cancer-prevention
#23
JOURNAL ARTICLE
Rebecca Stone, Joseph V Sakran, Kara Long Roche
No abstract text is available yet for this article.
June 20, 2023: JAMA
https://read.qxmd.com/read/37195163/adoption-of-complete-bilateral-salpingectomy-for-permanent-contraception-at-time-of-cesarean-delivery-in-rhode-island
#24
JOURNAL ARTICLE
Jessica B DiSilvestro, Christina A Raker, Jessica Velasquez, Cara A Mathews
OBJECTIVE: Complete bilateral salpingectomy (CBS) can decrease the risk of developing ovarian cancer, although adoption of CBS at cesarean delivery (CD) for permanent contraception has been low. The primary objective was to measure the annual rates of CBS at CD before and after an educational initiative. The secondary objective was to assess rates of providers who offer CBS at CD and their comfort level with the procedure. METHODS: We performed an observational study of OBGYN physicians who perform CD at a single institution...
June 1, 2023: Rhode Island Medical Journal
https://read.qxmd.com/read/37116391/patient-perspectives-on-risk-reducing-salpingectomy-with-delayed-oophorectomy-for-ovarian-cancer-risk-reduction-a-systematic-review-of-the-literature
#25
REVIEW
Luiza Perez, Emily Webster, Leslie Bull, Jesse T Brewer, Muhammad Danyal Ahsan, Jenny Lin, Sarah R Levi, Evelyn Cantillo, Eloise Chapman-Davis, Kevin Holcomb, Shoshana M Rosenberg, Melissa K Frey
OBJECTIVE: Increasing evidence suggests the fallopian tube as the site of origin of BRCA1/2-associated high-grade ovarian cancers. Several ongoing trials are evaluating salpingectomy with delayed oophorectomy (RRSDO) for ovarian cancer risk reduction and patients are beginning to ask their clinicians about this surgical option. This study sought to systematically review the available literature examining patient preferences regarding RRSDO and risk-reducing salpingo-oophorectomy (RRSO) to provide clinicians with an understanding of patient values, concerns, and priorities surrounding ovarian cancer risk-reducing surgery...
April 26, 2023: Gynecologic Oncology
https://read.qxmd.com/read/37059410/quality-of-life-after-risk-reducing-surgery-for-breast-and-ovarian-cancer-prevention-a-systematic-review-and-meta-analysis
#26
REVIEW
Xia Wei, Samuel Oxley, Michail Sideris, Ashwin Kalra, Adam Brentnall, Li Sun, Li Yang, Rosa Legood, Ranjit Manchanda
OBJECTIVE: This study aimed to assess the impact of risk-reducing surgery for breast cancer and ovarian cancer prevention on quality of life. We considered risk-reducing mastectomy, risk-reducing salpingo-oophorectomy, and risk-reducing early salpingectomy and delayed oophorectomy. DATA SOURCES: We followed a prospective protocol (International Prospective Register of Systematic Reviews: CRD42022319782) and searched MEDLINE, Embase, PubMed, and Cochrane Library from inception to February 2023...
October 2023: American Journal of Obstetrics and Gynecology
https://read.qxmd.com/read/37046723/increased-local-testosterone-levels-alter-human-fallopian-tube-mrna-profile-and-signaling
#27
JOURNAL ARTICLE
Angela Russo, Brian P Cain, Tia Jackson-Bey, Alfredo Lopez Carrero, Jane Miglo, Shannon MacLaughlan, Brett C Isenberg, Jonathan Coppeta, Joanna E Burdette
Fallopian tube epithelium (FTE) plays a critical role in reproduction and can be the site where High Grade Serous Ovarian Carcinoma (HGSOC) originates. Tumorigenic oviductal cells, which are the murine equivalent of human fallopian tube secretory epithelial cells (FTSEC), enhance testosterone secretion by the ovary when co-cultured with the ovary, suggesting that testosterone is part of the signaling axis between the ovary and FTSEC. Furthermore, testosterone promotes proliferation of oviductal cells. Oral contraceptives, tubal ligation, and salpingectomy, which are all protective against developing ovarian cancer, also decrease circulating levels of androgen...
March 30, 2023: Cancers
https://read.qxmd.com/read/37045546/tubectomy-with-delayed-oophorectomy-as-an-alternative-to-risk-reducing-salpingo-oophorectomy-in-high-risk-women-to-assess-the-safety-of-prevention-the-tuba-wisp-ii-study-protocol
#28
JOURNAL ARTICLE
Miranda P Steenbeek, Majke H D van Bommel, Joanna intHout, Christine B Peterson, Michiel Simons, Kit C B Roes, Marleen Kets, Barbara M Norquist, Elizabeth M Swisher, Rosella P M G Hermens, Karen H Lu, Joanne A de Hullu
BACKGROUND: Risk-reducing salpingectomy with delayed oophorectomy has gained interest for individuals at high risk for tubo-ovarian cancer as there is compelling evidence that especially high-grade serous carcinoma originates in the fallopian tubes. Two studies have demonstrated a positive effect of salpingectomy on menopause-related quality of life and sexual health compared with standard risk-reducing salpingo-oophorectomy. PRIMARY OBJECTIVE: To investigate whether salpingectomy with delayed oophorectomy is non-inferior to the current standard salpingo-oophorectomy for the prevention of tubo-ovarian cancer among individuals at high inherited risk...
April 12, 2023: International Journal of Gynecological Cancer
https://read.qxmd.com/read/37042549/opportunistic-salpingectomy-for-ovarian-cancer-prevention-a-call-for-action
#29
JOURNAL ARTICLE
Mariona Rius, José Carugno, Abrao Maurico S, Francisco Carmona
No abstract text is available yet for this article.
April 12, 2023: Journal of the American College of Surgeons
https://read.qxmd.com/read/36959664/hoppsa-update-changes-in-the-study-protocol-of-hysterectomy-and-opportunistic-salpingectomy-a-registry-based-randomized-controlled-trial
#30
JOURNAL ARTICLE
Annika Idahl, Per Liv, Anna Darelius, Elin Collins, Karin Sundfeldt, Mathias Pålsson, Annika Strandell
BACKGROUND: The HOPPSA trial is a multi-center national registry-based randomized controlled trial to test the safety and effectiveness of performing opportunistic salpingectomy at hysterectomy to reduce the risk of epithelial ovarian cancer (EOC). The study protocol was first published in January 2019 and is available at https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-018-3083-8 . Here, we report amendments made to the study protocol since commencement of the trial. CHANGES IN METHODS AND ANALYSIS: The primary outcomes analyses have been changed...
March 24, 2023: Trials
https://read.qxmd.com/read/36938343/prevention-over-screening-for-ovarian-cancer-in-patients-with-high-risk-germline-mutations-misinterpreting-the-findings-of-aldo
#31
JOURNAL ARTICLE
Beryl L Manning-Geist, Matthew Flint, Kara Long Roche
In November 2022, the findings of the Avoiding Late Diagnosis of Ovarian cancer (ALDO) study were published. Subsequent media coverage suggested that investigators had found a safe alternative to risk-reducing bilateral salpingoophorectomy (rrBSO) in patients with pathogenic BRCA1 and BRCA2 germline mutations who chose to decline or defer risk-reducing surgery. Unfortunately, this media coverage was largely misleading. Specifically, in the ALDO trial, 4 of 6 patients found to have ovarian cancer by the ALDO screening methodology were diagnosed with advanced-stage disease...
April 2023: Gynecologic Oncology Reports
https://read.qxmd.com/read/36917763/prophylactic-salpingectomy-with-delayed-oophorectomy-as-a-two-staged-alternative-for-primary-prevention-of-ovarian-cancer-in-brca1-2-mutation-carriers-women-s-point-of-view
#32
JOURNAL ARTICLE
Aya Mohr-Sasson, Tal Dadon, Tamar Perri, Orgad Rosenblat, Eitan Friedman, Jacob Korach
OBJECTIVE: This study aimed to determine BRCA-mutation carrier women's interest and acceptability of participating in a study examining prophylactic salpingectomy with delayed oophorectomy (PSDO) as an alternative to the current recommendation for bilateral salpingo-oophorectomy for risk reduction. METHODS: This is a cross-sectional questionnaire-based study. All women visiting the high-risk clinics for hereditary breast and ovarian cancer in a single tertiary medical center were asked to complete a questionnaire concerning the two-stage approach from October 2018 to December 2019...
March 14, 2023: Menopause: the Journal of the North American Menopause Society
https://read.qxmd.com/read/36897130/postpartum-opportunistic-salpingectomy-compared-with-bilateral-tubal-ligation-after-vaginal-delivery-for-ovarian-cancer-risk-reduction-a-cost-effectiveness-analysis
#33
JOURNAL ARTICLE
Matthew K Wagar, Grayson L Forlines, Nicholas Moellman, Anisa Carlson, Michael Matthews, Makeba Williams
OBJECTIVE: To compare the cost effectiveness of opportunistic salpingectomy and bilateral tubal ligation for sterilization immediately after vaginal delivery. METHODS: A cost-effectiveness analytic decision model was used to compare opportunistic salpingectomy with bilateral tubal ligation during vaginal delivery admission. Probability and cost inputs were derived from local data and available literature. Salpingectomy was assumed to be performed with a handheld bipolar energy device...
March 9, 2023: Obstetrics and Gynecology
https://read.qxmd.com/read/36875151/pasteurella-multocida-bacteremia-a-case-report-of-pelvic-cavity-inflammation-with-abnormal-uterine-bleeding-fever-and-sclerotic-bone-lesions
#34
Priya Mohan, Ashley R Diaz, Siwon Lee
BACKGROUND: Pasteurella multocida , is a bacterium that is frequently transmitted to humans from domestic pets. Infections are generally localized, but previous reports have exhibited that Pasteurella can cause systemic infections such as peritonitis, bacteremia and in some rare cases tubo-ovarian abscess. CASE PRESENTATION: We present a case of a 46-year-old woman who came to the emergency department (ED) with complaints of pelvic pain, abnormal uterine bleeding (AUB), and fever...
2023: IDCases
https://read.qxmd.com/read/36847838/ovarian-cancer-prevention-by-opportunistic-salpingectomy-is-a-new-de-facto-standard-in-germany
#35
JOURNAL ARTICLE
I B Runnebaum, A Kather, J Vorwergk, J J Cruz, A R Mothes, C R Beteta, J Boer, M Keller, M Pölcher, A Mustea, J Sehouli
PURPOSE: The most prevalent and aggressive subtype of epithelial ovarian carcinoma (EOC), high-grade serous carcinoma (HGSC), originates in many cases from the fallopian tubes. Because of poor prognosis and lack of effective screening for early detection, opportunistic salpingectomy (OS) for prevention of EOC is being implemented into clinical routine in several countries worldwide. Taking the opportunity of a gynecological surgery in women at average cancer risk, extramural fallopian tubes are completely resected preserving the ovaries with their infundibulopelvic blood supply...
August 2023: Journal of Cancer Research and Clinical Oncology
https://read.qxmd.com/read/36814422/opportunistic-salpingectomy-for-the-primary-prevention-of-ovarian-cancer
#36
LETTER
Ingo B Runnebaum, Angela Kather, Jalid Sehouli
No abstract text is available yet for this article.
December 9, 2022: Deutsches Ärzteblatt International
https://read.qxmd.com/read/36720520/frequency-of-serous-tubal-intraepithelial-carcinoma-stic-in-patients-with-high-grade-serous-ovarian-cancer
#37
JOURNAL ARTICLE
Jung Mi Byun, Hwa Jin Cho, Dae Sim Lee, Hye Kyoung Yoon, Young Nam Kim, Do Hwa Im, Da Hyun Kim, Kyung Bok Lee, Moon Su Sung, Dae Hoon Jeong
OBJECTIVE: Serous tubal intraepithelial carcinoma (STIC) is a known precursor of high-grade serous ovarian cancer (HGSOC). This study aimed to evaluate the proportion of STIC in patients with HGSOC and analyze the STIC-related prognosis in patients with HGSOC. MATERIALS AND METHODS: All pathology reports at our institution that included bilateral salpingectomies of patients with HGSOC from January 2013 to December 2018 were reviewed by two experienced pathologists...
January 2023: Taiwanese Journal of Obstetrics & Gynecology
https://read.qxmd.com/read/36707423/a-questionnaire-based-survey-on-the-diagnostic-and-therapeutic-approaches-for-patients-with-stic-in-germany
#38
JOURNAL ARTICLE
Josche van der Ven, Valerie Catherine Linz, Katharina Anic, Mona Wanda Schmidt, Amelie Loewe, Slavomir Krajnak, Marcus Schmidt, Stefan Kommoss, Barbara Schmalfeldt, Jalid Sehouli, Annette Hasenburg, Marco Johannes Battista
PURPOSE: Despite the growing understanding of the carcinogenesis of pelvic high-grade serous carcinoma (HGSC) of the ovary and peritoneum and its precursor lesion serous tubal intraepithelial carcinoma (STIC), evidence-based proven recommendations on the clinical management of patients with STIC are lacking so far. METHODS: A questionnaire containing 21 questions was developed to explore the clinical experience with patients with the diagnosis of STICs and the diagnostic, surgical and histopathological approaches in Germany...
January 27, 2023: Archives of Gynecology and Obstetrics
https://read.qxmd.com/read/36687155/opportunistic-salpingectomy-during-robotic-sacrocolpopexy-data-to-support-a-widely-accepted-practice
#39
JOURNAL ARTICLE
Anna Dukhovich, Marie E Sullivan, Josette Hartnett, Suzanne J Rose, Brian J Hines
While surgical outcomes of prophylactic salpingectomy as an ovarian cancer risk reducing measure at the time of hysterectomy for benign indications has already been studied, data has traditionally been extrapolated to surgery for prolapse repair. A retrospective chart review was performed from medical records of patients who had undergone a sacrocolpopexy for pelvic organ prolapse. Variables collected included operation duration, length of hospital stay, readmission within 31 days, estimated blood loss (EBL), number and size of incisions, as well as narcotic use during hospitalization...
February 2023: Data in Brief
https://read.qxmd.com/read/36661074/first-step-in-implementation-of-opportunistic-salpingectomy-for-prevention-of-ovarian-cancer-current-care-and-its-determinants
#40
JOURNAL ARTICLE
Malou E Gelderblom, Veerle Jaspers, Reinier P Akkermans, Brigitte Slangen, Angele L M Oei, Alexandra A van Ginkel, Huy Ngo, Joanna IntHout, Rosella P M G Hermens, Joanne A de Hullu, Jurgen M J Piek
INTRODUCTION: Opportunistic salpingectomy (OS) refers to additional removal of the fallopian tubes during abdominal surgery performed for another medical indication, as prevention for ovarian cancer. As OS has been inconsistently implemented, its clinical practice varies worldwide. To reduce this variation, insight is required into current clinical practice and its determinants. Therefore, the study aim was to determine the implementation of counseling and performance of OS between 2015 and 2018, and its patient, surgical, physician, and hospital characteristics...
March 2023: Acta Obstetricia et Gynecologica Scandinavica
keyword
keyword
23408
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.