Sweeta D Gandhi, Richard B Weiskopf, Cornelius Jungheinrich, Robert Koorn, Diane Miller, Robert E Shangraw, Donald S Prough, Daniela Baus, Frank Bepperling, David C Warltier
BACKGROUND: The purpose of this study was to test the equivalence of efficacy and compare the safety of the 6% hydroxyethyl starches (HES) Voluven (HES 130/0.4; Fresenius Kabi, Bad Homburg, Germany) and hetastarch (HES 670/0.75 in saline) for intravascular volume replacement therapy during major orthopedic surgery. METHODS: In a prospective, controlled, randomized, double-blind, multicenter trial of patients undergoing major orthopedic surgery, 49 patients were treated with HES 130/0...
June 2007: Anesthesiology