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https://www.readbyqxmd.com/read/28404935/outcomes-of-metastatic-spinal-cord-compression-secondary-to-primary-hepatocellular-carcinoma-with-multidisciplinary-treatments
#1
Shaohui He, Haifeng Wei, Yifei Ma, Jian Zhao, Wei Xu, Jianru Xiao
Few studies have reported progression-free survival (PFS) and overall survival (OS) of Metastatic spinal cord compression (MSCC) patients with primary hepatocellular carcinoma (HCC) following surgery and adjuvant therapies. Enrolled in this study were 155 MSCC patients with primary HCC who received surgery and adjuvant therapies between 2000 and 2015. Kaplan-Meier methods and Cox's proportional hazards regression mode were performed to investigate the clinical features and prognostic factors affecting PFS and OS...
February 25, 2017: Oncotarget
https://www.readbyqxmd.com/read/28264589/minimally-invasive-spinal-surgery-for-the-management-of-symptomatic-spinal-metastasis
#2
Abdulkader Hamad, Leonidas Vachtsevanos, Andrew Cattell, Matthew Ockendon, Birender Balain
INTRODUCTION: Symptomatic metastatic spinal disease is on the increase. Minimally invasive spinal surgery has been associated with a lower complication profile when compared to traditional open methods; however there is paucity of literature evaluating the place of percutaneous pedicle screw fixation (PPSF) in the management of spinal metastases. The purpose of the study is to assess the efficacy of Minimally Invasive Spine Surgery (MISS) using PPSF with or without mini-decompression in the management of symptomatic spinal metastases...
March 6, 2017: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/28249653/management-of-the-clinically-node-negative-neck-in-squamous-cell-carcinoma-of-the-maxilla
#3
Michiel H M A Joosten, Remco de Bree, Ellen M Van Cann
OBJECTIVE: The management of the clinically node negative (N0) neck in patients with squamous cell carcinoma of the maxilla (MSCC) is a matter of debate. In this retrospective cohort study the incidence of occult metastases is determined in clinically N0 MSCCs, as well as histopathological factors associated with occult metastases. PATIENTS AND METHODS: 95 patients with clinically N0 MSCCs had maxillectomy. 18 patients with elective treatment of the neck were excluded...
March 2017: Oral Oncology
https://www.readbyqxmd.com/read/28194222/intelligibility-evaluation-of-pathological-speech-through-multigranularity-feature-extraction-and-optimization
#4
Chunying Fang, Haifeng Li, Lin Ma, Mancai Zhang
Pathological speech usually refers to speech distortion resulting from illness or other biological insults. The assessment of pathological speech plays an important role in assisting the experts, while automatic evaluation of speech intelligibility is difficult because it is usually nonstationary and mutational. In this paper, we carry out an independent innovation of feature extraction and reduction, and we describe a multigranularity combined feature scheme which is optimized by the hierarchical visual method...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/28193282/preoperative-embolization-in-patients-with-metastatic-spinal-cord-compression-mandatory-or-optional
#5
Chul Gie Hong, Jae Hwan Cho, Dae Chul Suh, Chang Ju Hwang, Dong-Ho Lee, Choon Sung Lee
BACKGROUND: The contribution of preoperative embolization in reducing intraoperative blood loss and its clinical importance are unclear. So, we aimed to compare the perioperative clinical outcomes based on whether preoperative embolization was performed and assess the role and safety of preoperative embolization in metastatic spinal cord compression (MSCC) patients. METHODS: We enrolled 52 patients (men, 37; women, 15) who underwent palliative decompression for MSCC...
February 14, 2017: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28181815/onsite-versus-offsite-radiation-treatment-of-malignant-spinal-cord-compression-lessons-from-a-safety-net-health-system
#6
COMPARATIVE STUDY
Albert C Chen, Mark D Bonnen, Henry Mok
OBJECTIVE: Metastatic spinal cord compression (MSCC) is an oncologic emergency that often warrants emergent treatment; but, it is unclear whether radiation treatment (RT) can be optimally managed from an offsite radiotherapy facility. METHODS: Patient charts from consecutive patients with MSCC who were treated with radiotherapy alone at either an onsite hospital radiation department (from 2008 to 2012) or an offsite radiotherapy centre (2012-2015) were reviewed...
April 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28138012/early-intervention-results-in-lower-mortality-in-patients-with-cancer-hospitalized-for-metastatic-spinal-cord-compression
#7
Achuta Kumar Guddati, Gagan Kumar, Iuliana Shapira
Metastatic spinal cord compression (MSCC) is one of the most dreaded complications of cancer. A Nationwide Inpatient Sample (NIS) from 2000 to 2011 was used to extract data for all in-hospital stays of patients with MSCC using the International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes. The usage and timing of radiation therapy and surgical interventions were identified using ICD-9-M codes. These interventions were defined as 'early intervention' if they were provided within the first 48 hours of hospitalization...
January 30, 2017: Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research
https://www.readbyqxmd.com/read/28116507/patient-s-experiences-of-being-discharged-home-from-hospital-following-a-diagnosis-of-malignant-spinal-cord-compression
#8
Jane Manson, Clare Warnock, Lesley Crowther
PURPOSE: The purpose of this study is to explore experiences in the days and weeks following discharge home following diagnosis and treatment for metastatic spinal cord compression (MSCC). METHODS: Eleven participants took part in audio-recorded semi-structured interviews about their experiences at 1 and 3-4 weeks post-discharge home following a diagnosis of MSCC. Transcripts were analysed using a framework approach. RESULTS: Time emerged as an overarching theme within the framework of four time points: past, present, near future and distant future...
January 23, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28066741/cell-therapy-for-cartilage-defects-of-the-hip
#9
Rodrigo Mardones, Alessio Giai Via, Claudio Jofré, José Minguell, Claudio Rodriguez, Alexander Tomic, Matias Salineros
BACKGROUND: Chondral injuries are commonly related to poor clinical outcome, but recent data showed some improvements in function and pain after hip arthroscopy. Cell-based therapies represent an appealing alternative strategy for cartilage regeneration, and interesting results have been recently reported after intra-articular injections of mesenchymal stem cells (MSCs). The results of hip arthroscopy for femoroacetabular impingement (FAI) and intra-articular injections of autologous expanded bone marrow - MSCs (BM-MSCs) are reported in this retrospective study...
July 2016: Muscles, Ligaments and Tendons Journal
https://www.readbyqxmd.com/read/27843413/effectiveness-of-radiotherapy-for-metastatic-spinal-cord-compression-in-patients-with-short-life-expectancy
#10
Alexandra Giraldo, Sergi Benavente, Mónica Ramos, Ramona Vergés, Odimar Coronil, Lina Arbeláez, Xavier Maldonado, Manuel Altabas, Meritxell Mollà, Victoria Reyes, Begoña Navalpotro, Jordi Giralt
AIM: To analyze the effect of radiotherapy (RT) in patients with metastatic spinal cord compression (MSCC) and poor prognosis in our center. BACKGROUND: RT is an effective treatment for MSCC. MATERIALS AND METHODS: Prospective evaluation on patients with MSCC and limited survival (according to Rades' scale), and treated with single-dose 8 Gy RT (February 2013-August 2014). Pain, ambulatory status and sphincter control were recorded. Pain relief was evaluated following the International Bone Metastases Consensus Working Party Guidelines...
January 2017: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27814990/the-effect-of-written-posted-instructions-on-collection-of-clean-catch-urine-specimens-in-the-emergency-department
#11
Patrick Joseph Maher, Alisha Emily Cutler Brown, Medley O'Keefe Gatewood
BACKGROUND: Urinalysis testing is frequently ordered in the emergency department (ED), but contamination of urine specimens limits the interpretation of results. The mid-stream, clean-catch (MSCC) procedure for urine specimen collection is recommended to decrease contamination rates, but without instructions this procedure has poor compliance. OBJECTIVE: To evaluate the effectiveness of written instructions alone, we analyzed the rate of specimen contamination, defined by presence of squamous epithelial cells (SECs) and culture results, in the ED after posting information on the MSCC procedure...
November 1, 2016: Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27804231/role-of-the-overall-treatment-time-of-radiotherapy-with-10%C3%A2-%C3%A3-%C3%A2-3%C3%A2-gy-for-outcomes-in-patients-with-metastatic-spinal-cord-compression
#12
Dirk Rades, Stefan Janssen, Antonio Jose Conde-Moreno, Jon Cacicedo, Michaela Metz, Theo Veninga, Barbara Segedin, Volker Rudat, Steven E Schild
INTRODUCTION: Radiotherapy alone still is the most commonly delivered treatment modality for metastatic spinal cord compression (MSCC). MSCC is an emergency situation, which requires treatment as soon as possible. When radiotherapy is performed with the most commonly used approach 10 × 3 Gy (30 Gy in 10 fractions) over 2 weeks, the question has been asked whether an overall treatment time (OTT) of 14-15 days including two weekends without irradiation leads to worse outcomes than OTT of 12 days (beginning of radiotherapy on a Monday resulting in only one weekend break)? METHODS: A total of 412 patients with MSCC were included in this retrospective study...
November 2, 2016: Journal of Medical Imaging and Radiation Oncology
https://www.readbyqxmd.com/read/27752060/preoperative-prediction-for-regaining-ambulatory-ability-in-paretic-non-ambulatory-patients-with-metastatic-spinal-cord-compression
#13
M Ohashi, T Hirano, K Watanabe, K Katsumi, H Shoji, A Sano, H Tashi, I Takahashi, M Wakasugi, Y Shibuya, N Endo
STUDY DESIGN: Retrospective multicenter study. OBJECTIVES: To analyze the predictive factors for postoperative ambulatory recovery in paretic non-ambulatory patients with metastatic spinal cord compression (MSCC). SETTING: Japan. METHODS: Eighty-two consecutive patients (74.4% men; mean age, 66.2 years) who could not walk before surgery due to cervical or thoracic MSCC and underwent posterior decompressive surgery between 2003 and 2014 were included...
October 18, 2016: Spinal Cord
https://www.readbyqxmd.com/read/27674903/spine-stereotactic-ablative-body-radiation-therapy-sabr-with-volumetric-modulated-arc-therapy-vmat-for-vertebral-metastases-with-and-without-metastatic-spinal-cord-compression-mscc
#14
M M Gestaut, N Thawani, S Kim, V R Gutti, A Morrow, R A Ward, J H Huang, M K Patel
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27627713/health-related-quality-of-life-in-patients-with-metastatic-spinal-cord-compression
#15
Søren S Morgen, Svend A Engelholm, Claus F Larsen, Rikke Søgaard, Benny Dahl
OBJECTIVE: Improvements in cancer treatment have resulted in an increased number of patients with metastatic spinal cord compression (MSCC). Because patients with MSCC often have a limited expected survival time, maintenance of a high functional level and quality of life are important. However, there is limited information about health-related quality of life (HRQoL) in patients with MSCC. The aim of this study was to examine the feasibility of routine assessment of HRQoL based on the Euroqol-5 dimensions (EQ-5D) questionnaire in a cohort of patients consecutively admitted for evaluation of acute symptoms of MSCC...
August 2016: Orthopaedic Surgery
https://www.readbyqxmd.com/read/27618393/cisplatin-and-cetuximab-treatment-for-metastatic-cutaneous-squamous-cell-carcinoma-a-systematic-review
#16
REVIEW
Cameron Trodello, Jon-Paul Pepper, Michael Wong, Ashley Wysong
BACKGROUND: Cutaneous squamous cell carcinoma (cSCC) is the second most common form of skin cancer and metastasizes in 2% to 5% of cases. OBJECTIVE: Systematic evaluation of published cases of metastatic cSCC (mSCC) treated with cisplatin or cetuximab from 1989 to 2014. MATERIALS AND METHODS: A literature search was performed to identify cases of mSCC treated with cisplatin or cetuximab. Patient demographics, tumor characteristics, response rates, and disease-free survivals were extracted...
January 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/27607403/the-relationship-between-preoperative-clinical-presentation-and-quantitative-magnetic-resonance-imaging-features-in-patients-with-degenerative-cervical-myelopathy
#17
Aria Nouri, Lindsay Tetreault, Kristian Dalzell, Juan J Zamorano, Michael G Fehlings
BACKGROUND: Degenerative cervical myelopathy encompasses a group of conditions resulting in progressive spinal cord injury through static and dynamic compression. Although a constellation of changes can present on magnetic resonance imaging (MRI), the clinical significance of these findings remains a subject of controversy and discussion. OBJECTIVE: To investigate the relationship between clinical presentation and quantitative MRI features in patients with degenerative cervical myelopathy...
January 1, 2017: Neurosurgery
https://www.readbyqxmd.com/read/27566097/prognosis-of-patients-with-metastatic-spinal-cord-compression-from-adrenocortical-carcinoma
#18
Stefan Janssen, Tobias Bartscht, Dirk Rades
BACKGROUND/AIM: Adrenocortical cancer is a rare aggressive type of cancer. The prognosis is poor, particularly for metastatic disease. This study focused on metastatic spinal cord compression (MSCC) from adrenocortical carcinoma. PATIENTS AND METHODS: Data of three patients who received palliative irradiation of MSCC from adrenocortical carcinoma were retrospectively analyzed for motor function, ambulatory status and survival. RESULTS: One patient died before completion of radiotherapy...
September 2016: In Vivo
https://www.readbyqxmd.com/read/27399447/168%C3%A2-impact-of-initial-clinical-and-imaging-parameters-on-long-term-neurological-outcomes-in-acute-traumatic-cervical-spinal-cord-injury
#19
Sunil Kukreja, Jan Schwab, Francis Farhadi
INTRODUCTION: The influence of initial clinical and imaging parameters on long-term outcomes following spinal cord injury (SCI) has been examined in previous studies, often with inconsistent or contradictory findings. In this study, we evaluated a comprehensive set of admission parameters and analyzed their relationships with long-term neurological recovery. METHODS: Institutional databases were used to retrospectively identify consecutive patients with cervical SCI admitted between 2008 and 2015...
August 2016: Neurosurgery
https://www.readbyqxmd.com/read/27193751/molten-salt-co2-capture-and-electro-transformation-mscc-et-into-capacitive-carbon-at-medium-temperature-effect-of-the-electrolyte-composition
#20
Bowen Deng, Zhigang Chen, Muxing Gao, Yuqiao Song, Kaiyuan Zheng, Juanjuan Tang, Wei Xiao, Xuhui Mao, Dihua Wang
Electrochemical transformation of CO2 into functional materials or fuels (i.e., carbon, CO) in high temperature molten salts has been demonstrated as a promising way of carbon capture, utilisation and storage (CCUS) in recent years. In a view of continuous operation, the electrolysis process should match very well with the CO2 absorption kinetics. At the same time, in consideration of the energy efficiency, a molten salt electrochemical cell running at lower temperature is more beneficial to a process powered by the fluctuating renewable electricity from solar/wind farms...
August 15, 2016: Faraday Discussions
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