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https://www.readbyqxmd.com/read/28093018/algorithm-for-bionic-hand-reconstruction-in-patients-with-global-brachial-plexopathies
#1
Laura A Hruby, Agnes Sturma, Johannes A Mayer, Anna Pittermann, Stefan Salminger, Oskar C Aszmann
OBJECTIVE Global brachial plexus lesions with multiple root avulsions are among the most severe nerve injuries, leading to lifelong disability. Fortunately, in most cases primary and secondary reconstructions provide a stable shoulder and restore sufficient arm function. Restoration of biological hand function, however, remains a reconstructive goal that is difficult to reach. The recently introduced concept of bionic reconstruction overcomes biological limitations of classic reconstructive surgery to restore hand function by combining selective nerve and muscle transfers with elective amputation of the functionless hand and its replacement with a prosthetic device...
January 17, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28091697/heat-shock-transcription-factor-1-protects-against-pressure-overload-induced-cardiac-fibrosis-via-smad3
#2
Ning Zhou, Yong Ye, Xingxu Wang, Ben Ma, Jian Wu, Lei Li, Lin Wang, Dao Wen Wang, Yunzeng Zou
: Fibrotic cardiac muscle exhibits high stiffness and low compliance which are major risk factors of heart failure. Although heat shock transcription factor 1 (HSF1) was identified as an intrinsic cardioprotective factor, the role that HSF1 plays in cardiac fibrosis remains unclear. Our study aims to investigate the role of HSF1 in pressure overload-induced cardiac fibrosis and the underlying mechanism. HSF1 phosphorylation was significantly downregulated in transverse aortic constriction (TAC)-treated mouse hearts and mechanically stretched cardiac fibroblasts (cFBs)...
January 13, 2017: Journal of Molecular Medicine: Official Organ of the "Gesellschaft Deutscher Naturforscher und Ärzte"
https://www.readbyqxmd.com/read/28079808/diagnosis-and-treatment-of-pediatric-benign-pneumoperitoneum-a-case-report-series-of-9-patients
#3
Shou-Xing Duan, Zong-Bo Sun, Guang-Huan Wang, Jun Zhong, Wen-Hui Ou, Ma-Xian Fu, Fu-Sheng Wang, Shu-Hua Ma, Jian-Hong Li
INTRODUCTION: Benign pneumoperitoneum (BPPT) is defined as asymptomatic free intraabdominal air or as pneumoperitoneum without peritonitis. Symptomatic free air requires surgical anagement, but management of asymptomatic pneumoperitoneum is controversial. In this study, we investigate the diagnosis and treatment of BPPT in children. CLINICAL FINDINGS: The clinical data of 9 pediatric patients with BPPT who were admitted to our hospital from January 2000 to January 2015 were retrospectively analyzed to summarize the diagnosis and treatment...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28077859/benefits-of-whole-body-vibration-training-on-arterial-function-and-muscle-strength-in-young-overweight-obese-women
#4
Stacey Alvarez-Alvarado, Salvador J Jaime, Michael J Ormsbee, Jeremiah C Campbell, Joy Post, Jacob Pacilio, Arturo Figueroa
The early arterial dysfunction linked with obesity and a sedentary lifestyle heightens the likelihood of suffering from future cardiovascular events. Whole-body vibration training (WBVT) may improve systemic arterial stiffness (brachial-ankle pulse wave velocity (baPWV)) and muscle strength in pre- and post-menopausal women. However, the effectiveness of WBVT to impact the arterial segments included in baPWV is unknown. The aim of this study was to investigate the effects of WBVT on aortic and leg arterial stiffness in young sedentary overweight/obese women...
January 12, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28068381/impairment-of-excitation-contraction-coupling-in-right-ventricular-hypertrophied-muscle-with-fibrosis-induced-by-pulmonary-artery-banding
#5
Yoichiro Kusakari, Takashi Urashima, Daisuke Shimura, Erika Amemiya, Genki Miyasaka, Shunsuke Yokota, Yoshitaka Fujimoto, Toru Akaike, Takahiro Inoue, Susumu Minamisawa
Interstitial myocardial fibrosis is one of the factors responsible for dysfunction of the heart. However, how interstitial fibrosis affects cardiac function and excitation-contraction coupling (E-C coupling) has not yet been clarified. We developed an animal model of right ventricular (RV) hypertrophy with fibrosis by pulmonary artery (PA) banding in rats. Two, four, and six weeks after the PA-banding operation, the tension and intracellular Ca2+ concentration of RV papillary muscles were simultaneously measured (n = 33)...
2017: PloS One
https://www.readbyqxmd.com/read/28065540/cardiac-shear-wave-velocity-detection-in-the-porcine-heart
#6
Hendrik J Vos, Bas M van Dalen, Ilkka Heinonen, Johan G Bosch, Oana Sorop, Dirk J Duncker, Antonius F W van der Steen, Nico de Jong
Cardiac muscle stiffness can potentially be estimated non-invasively with shear wave elastography. Shear waves are present on the septal wall after mitral and aortic valve closure, thus providing an opportunity to assess stiffness in early systole and early diastole. We report on the shear wave recordings of 22 minipigs with high-frame-rate echocardiography. The waves were captured with 4000 frames/s using a programmable commercial ultrasound machine. The wave pattern was extracted from the data through a local tissue velocity estimator based on one-lag autocorrelation...
January 5, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28051342/effects-of-thermal-agent-and-physical-activity-on-muscle-tendon-stiffness-and-effects-combined-with-static-stretching
#7
Kosuke Fujita, Masatoshi Nakamura, Hiroki Umegaki, Takuya Kobayashi, Satoru Nishishita, Hiroki Tanaka, Satoko Ibuki, Noriaki Ichihashi
CONTEXT: A recent review or article reported that thermal agents (TA) or physical activity (PA) can increase range of motion (ROM), and that the combination of TA with stretching is superior to performing stretching only. However, since ROM is affected by the participants' psychological factors, it is questionable whether these studies measured the effect of these intervention on muscle flexibility. By measuring muscle stiffness, we attempted to evaluate the effect these intervention on muscle flexibility...
January 4, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28050744/simulation-studies-of-the-role-of-esophageal-mucosa-in-bolus-transport
#8
Wenjun Kou, John E Pandolfino, Peter J Kahrilas, Neelesh A Patankar
Based on a fully coupled computational model for esophageal transport, we analyzed the role of the mucosa (including the submucosa) in esophageal bolus transport and how bolus transport is affected by mucosal stiffness. Two groups of studies were conducted using a computational model. In the first group, a base case that represents normal esophageal transport and two hypothetical cases were simulated: (1) esophageal mucosa replaced by muscle and (2) esophagus without mucosa. For the base case, the geometric configuration of the esophageal wall was examined and the mechanical role of mucosa was analyzed...
January 3, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28044365/clinical-implications-and-hospital-outcome-of-immune-mediated-myositis-in-horses
#9
L Hunyadi, E A Sundman, P H Kass, D C Williams, M Aleman
BACKGROUND: Immune-mediated myositis (IMM) is a cause of rhabdomyolysis, stiffness, and muscle atrophy predominantly affecting Quarter horses. Limited information is available with regard to outcome, prognostic indicators, and associations with concurrent diseases. HYPOTHESIS/OBJECTIVES: To report outcomes and associations between outcome and clinical and laboratory parameters, and presence of concurrent illness. ANIMALS: Sixty-eight horses; 52 Quarter horses and related breeds and 16 other breeds...
January 2, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28039045/impact-of-age-gender-and-body-composition-on-bone-quality-in-an-adult-population-from-the-middle-areas-of-china
#10
Zenghui Ding, Yanyan Chen, Yang Xu, Xu Zhou, Yubing Xu, Zuchang Ma, Yining Sun
Identifying modifiable factors that influence bone status during adulthood to maximize bone quality is a potential primary strategy in the prevention of osteoporosis in later life. We investigated the impact of body height, body weight, body mass index, and body composition on calcaneal bone characteristics as measured with quantitative ultrasound in 441 Chinese adults (238 women) aged 20-55 yr from the middle areas of China. Body composition, including fat-free mass (FFM), muscle mass, and fat mass were obtained by bioelectrical impedance analysis...
December 27, 2016: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28017954/-the-effect-of-exercise-and-sports-on-musculoskeletal-health-in-the-elderly
#11
Atsushi Harada
There is insufficient information on the effect of exercise and sports on musculoskeletal health in the elderly. Although the effects of sports are still unclear, the effects of exercise could be significant. For example, exercise improves osteoporosis by increasing bone mineral density and ameliorates sarcopenia by increasing muscle mass, muscular strength, and walking speed. As a result, fall risk is reduced and fracture risk is also likely to improve. Tai Chi is reportedly effective for joint pain and stiffness, and may improve symptoms of osteoarthritis...
2017: Clinical Calcium
https://www.readbyqxmd.com/read/28017188/comparing-trigger-point-dry-needling-and-manual-pressure-technique-for-the-management-of-myofascial-neck-shoulder-pain-a-randomized-clinical-trial
#12
Kayleigh E De Meulemeester, Birgit Castelein, Iris Coppieters, Tom Barbe, Ann Cools, Barbara Cagnie
OBJECTIVE: The aim of this study was to investigate short-term and long-term treatment effects of dry needling (DN) and manual pressure (MP) technique with the primary goal of determining if DN has better effects on disability, pain, and muscle characteristics in treating myofascial neck/shoulder pain in women. METHODS: In this randomized clinical trial, 42 female office workers with myofascial neck/shoulder pain were randomly allocated to either a DN or MP group and received 4 treatments...
January 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/28012296/effects-of-aging-on-mechanical-properties-of-sternocleidomastoid-and-trapezius-muscles-during-transition-from-lying-to-sitting-position-a-cross-sectional-study
#13
Piotr Kocur, Marcin Grzeskowiak, Marzena Wiernicka, Magdalena Goliwas, Jacek Lewandowski, Dawid Łochyński
AIM: The aim of this study was to analyze the effects of aging on the viscoelastic properties of the upper trapezius (UT) and the sternocleidomastoid (SCM) muscle during transition from lying to sitting position. MATERIALS AND METHODS: The study included 39 older (mean age 67±5.9years) and 36 younger (21.1±1.8years) women. Tone, stiffness and elasticity of the UT and the SCM were measured by means of myotonometry (MyotonPRO) in lying and then, in sitting position...
December 15, 2016: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/28010997/patellar-tendon-mechanical-properties-change-with-gender-body-mass-index-and-quadriceps-femoris-muscle-strength
#14
Serkan Taş, Seval Yılmaz, Mehmet Ruhi Onur, Abdullah Ruhi Soylu, Onur Altuntaş, Feza Korkusuz
OBJECTIVE: The purpose of this study is to assess the effect and correlation of gender, body mass index (BMI) and quadriceps femoris (QF) muscle strength on patellar tendon (PT) thickness and stiffness in healthy sedentary individuals. METHODS: This study was carried out with 67 (36 female, 31 male) healthy sedentary individuals between the ages of 18-44 (28.0 ± 7.5 years). The individuals included in the study were divided into two groups according to their gender and BMI (18...
December 20, 2016: Acta Orthopaedica et Traumatologica Turcica
https://www.readbyqxmd.com/read/28010122/lysyl-oxidase-induces-vascular-oxidative-stress-and-contributes-to-arterial-stiffness-and-abnormal-elastin-structure-in-hypertension-role-of-p38mapk
#15
Sonia Martínez-Revelles, Ana Belen Garcia-Redondo, Mª Soledad Avendaño, Saray Varona, Teresa Palao, Mar Orriols, Fernanda R Roque, Ana Fortuño, Rhian M Touyz, Jose Martínez-Gonzalez, Mercedes Salaices, Cristina Rodríguez, Ana María Briones
AIMS: Vascular stiffness, structural elastin abnormalities and increased oxidative stress are hallmarks of hypertension. Lysyl oxidase (LOX) is an elastin cross-linking enzyme that produces H<sub>2</sub>O<sub>2</sub> as by-product. We addressed the interplay between LOX, oxidative stress, vessel stiffness and elastin. RESULTS: Angiotensin II (Ang II)-infused hypertensive mice and spontaneously hypertensive rats (SHR) showed increased vascular LOX expression and stiffness and abnormal elastin structure...
December 23, 2016: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/28005829/reproducible-measurements-of-muscle-characteristics-using-the-myotonpro-device-comparison-between-individuals-with-and-without-paratonia
#16
Bieke Van Deun, Johannes S M Hobbelen, Barbara Cagnie, Birgit Van Eetvelde, Nele Van Den Noortgate, Dirk Cambier
BACKGROUND AND PURPOSE: The MyotonPRO is a portable device that measures muscle tone and biomechanical muscle properties objectively. MyotonPRO has already proven to be effective in measuring muscle properties in healthy and diseased populations. However, to the best of our knowledge, it has never been tested in individuals suffering from paratonia, a form of hypertonia frequently accompanying dementia. The aims of the present study were to (1) compare muscle tone, elasticity, and stiffness between 3 different subpopulations of young and old healthy adults and individuals with paratonia, and (2) investigate the intra- and interrater reproducibility of MyotonPRO measurements of the biceps brachii (BB) muscle in each subpopulation...
December 21, 2016: Journal of Geriatric Physical Therapy
https://www.readbyqxmd.com/read/28005706/endothelin-type-a-receptor-blockade-reduces-vascular-calcification-and-inflammation-in-rats-with-chronic-kidney-disease
#17
Richard Larivière, Alexandra Gauthier-Bastien, Roth-Visal Ung, Julie St-Hilaire, Fabrice Mac-Way, Darren E Richard, Mohsen Agharazii
OBJECTIVE: Arterial stiffness and calcification are nontraditional cardiovascular risk factors in chronic kidney disease (CKD). Using a rat model of CKD with mineral imbalance, medial vascular calcification has been associated with inflammation and increased endothelin-1 (ET-1) production. We therefore hypothesized that ET-1, through the endothelin type A (ETA) receptor, induces vascular inflammation, calcification and stiffness in CKD. METHODS: CKD was induced in Wistar rats by renal mass ablation...
February 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28003609/the-development-of-vibration-system-for-applying-magnetic-resonance-elastography-mre-to-the-supraspinatus-muscle
#18
Daiki Ito, Tomokazu Numano, Kazuyuki Mizuhara, Kouichi Takamoto, Takaaki Onishi, Hisao Nishijo
Palpation is a standard clinical tool to diagnose abnormal stiffness changes in soft tissues. However, it is difficult to palpate the supraspinatus muscle because it locates under the trapezius muscle. The magnetic resonance elastography (MRE) uses harmonic mechanical excitation to quantitatively measure the stiffness (shear modulus) of both the superficial and deep tissues. The purpose of this study was to build a vibration system for applying the MRE to the supraspinatus muscle. In this study, a power amplifier and a pneumatic pressure generator were used to supply vibrations to a vibration pad...
2016: Nihon Hoshasen Gijutsu Gakkai Zasshi
https://www.readbyqxmd.com/read/28003268/inhibition-of-srf-myocardin-reduces-aortic-stiffness-by-targeting-vascular-smooth-muscle-cell-stiffening-in-hypertension
#19
Ning Zhou, Jia-Jye Lee, Shaunrick Stoll, Ben Ma, Robert Wiener, Charles Wang, Kevin D Costa, Hongyu Qiu
AIMS: Increased aortic stiffness is a fundamental manifestation of hypertension. However, the molecular mechanisms involved remain largely unknown. We tested the hypothesis that abnormal intrinsic vascular smooth muscle cell (VSMC) mechanical properties in large arteries, but not in distal arteries, contribute to the pathogenesis of aortic stiffening in hypertension, mediated by the serum response factor (SRF)/myocardin signalling pathway. METHODS AND RESULTS: Four month old male spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto (WKY) rats were studied...
October 23, 2016: Cardiovascular Research
https://www.readbyqxmd.com/read/27999456/investigating-the-effect-of-intra-articular-platelet-rich-plasma-injection-on-union-pain-and-function-improvement-in-patients-with-scaphoid-fracture
#20
Hamid Namazi, Toomaj Kayedi
Introduction Fracture of the scaphoid bone is the most common fracture of the carpus. However, the fracture union occurs late or may not heal. Sometimes, fracture healing requires prolong immobilization. Because of potential for joint stiffness, muscle atrophy, or the inability to use the hand during and after prolonged immobilization, there is great incentive to develop therapies that will accelerate bone healing and allow a quick return to work. To date, the effect of platelet-rich plasma (PRP) on scaphoid fracture has not been studied...
December 2016: Journal of Hand and Microsurgery
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