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https://www.readbyqxmd.com/read/28228100/influence-of-hooks-and-a-lag-screw-on-internal-fixation-plates-for-lateral-malleolar-fracture-a-biomechanical-and-ergonomic-study
#1
Rina Sakai, Masataka Uchino, Terumasa Yoneo, Yasuaki Ohtaki, Hiroaki Minehara, Terumasa Matsuura, Tsutomu Gomi, Masanobu Ujihira
BACKGROUND: For internal fixation of AO classification Type B lateral malleolar fracture, insertion of lag screws into the fracture plane and fixation with a one-third tubular plate as a neutralization plate are the standard treatment procedures. The one-third tubular plate is processed to a hook shape and hung on the distal end of the fibula. In this study, to compare the function of the hook and lag screws of a one-third tubular plate and LCP for osteosynthesis of lateral malleolar fracture, mechanical indices of internal fixation were compared among the one-third tubular plates with lag screws with and without the hook and a locking compression plate...
February 23, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28227641/optimization-of-an-unpowered-energy-stored-exoskeleton-for-patients-with-spinal-cord-injury
#2
Xinyu Guan, Linhong Ji, Rencheng Wang, Wenjie Huang, Xinyu Guan, Linhong Ji, Rencheng Wang, Wenjie Huang, Rencheng Wang, Xinyu Guan, Wenjie Huang, Linhong Ji
The paper describes a novel unpowered energy-stored exoskeleton (ES-EXO) for spinal cord injured patients in consideration of patients' characteristics and injured levels. It proposed a method to optimize the energy-stored element to decrease the hip joint moment in walking. EMG patterns, ground reaction force and motion data from one participant with complete spinal cord injury at T10 were recorded. A combined human-ES-EXO model was built and the stored-energy element including locations and stiffness of springs were optimized in AnyBody Modeling System...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227557/sudden-changes-in-walking-surface-compliance-evoke-contralateral-emg-in-a-hemiparetic-walker-a-case-study-of-inter-leg-coordination-after-neurological-injury
#3
Jeffrey Skidmore, Panagiotis Artemiadis, Jeffrey Skidmore, Panagiotis Artemiadis, Jeffrey Skidmore, Panagiotis Artemiadis
Gait impairment due to neurological disorders is a significant problem around the world. Despite the growing interest in using robotic devices for gait rehabilitation, their widespread use remains limited as there is no clear evidence that robot-assisted gait therapy is superior to traditional treadmill-based therapy. This work is a case study that focuses on investigating the existence of mechanisms of inter-leg coordination after neurological injury, and based on that, proposing novel methods for gait rehabilitation...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227117/altered-viscoelastic-properties-of-stroke-affected-muscles-estimated-using-ultrasound-shear-waves-preliminary-data
#4
Ghulam Rasool, Allison B Wang, William Z Rymer, Sabrina S M Lee, Ghulam Rasool, Allison B Wang, William Z Rymer, Sabrina S M Lee, Ghulam Rasool, Sabrina S M Lee, Allison B Wang, William Z Rymer
As a result of a brain injury such as stroke, the skeletal muscles may undergo numerous structural and functional alterations. These abnormal changes are linked to muscle weakness, joint contracture, and abnormal muscle tone and eventually, result in motor impairment. A subset of these alterations affects passive muscle stiffness, i.e., viscoelastic properties. However, in vivo estimation of changes in viscoelastic properties is a challenging task. Here, we used the shear wave velocity, estimated through ultrasound SuperSonic imaging (SSI), as a surrogate for viscoelastic properties...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227116/force-controlled-ultrasound-to-measure-passive-mechanical-properties-of-muscle-in-duchenne-muscular-dystrophy
#5
Anne J Pigula, Jim S Wu, Matthew W Gilbertson, Basil T Darras, Seward B Rutkove, Brian W Anthony, Anne J Pigula, Jim S Wu, Matthew W Gilbertson, Basil T Darras, Seward B Rutkove, Brian W Anthony, Anne J Pigula, Brian W Anthony, Seward B Rutkove, Basil T Darras, Jim S Wu, Matthew W Gilbertson
The purpose of this study is to assess differences in skeletal muscle compressibility between patients with Duchenne muscular dystrophy (DMD) and normal subjects. The transverse passive mechanical properties of muscle, particularly those related to stiffness and elasticity, can be measured using force-controlled ultrasound. We acquired ultrasound videos of muscle compression under known pressures in the biceps and quadriceps in 23 boys with DMD and 20 age-matched healthy controls. We calculated the bulk linear spring constant, nonlinear stress-strain response, and average Young's modulus for each...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226961/knee-orthosis-with-variable-stiffness-and-damping-that-simulates-hemiparetic-gait
#6
Christina-Anne Lahiff, Tyagi Ramakrishnan, Seok Hun Kim, Kyle Reed, Christina-Anne Lahiff, Tyagi Ramakrishnan, Seok Hun Kim, Kyle Reed, Christina-Anne Lahiff, Kyle Reed, Tyagi Ramakrishnan, Seok Hun Kim
Individuals with unilateral stroke have neuromuscular weakness or paralysis on one side of the body caused by some muscles disengaging and others overexciting. Hyperextension of the knee joint and complete lack of plantar flexion of the ankle joint are common symptoms of stroke. This paper focuses on the creation and implementation of a small, lightweight, and adjustable orthotic device to be positioned around the knee of an able-bodied person to simulate hemiparetic gait. Force and range of motion data from able-bodied subjects fitted with the orthosis, inducing hemiparetic gait, was collected using the Computer Assisted Rehabilitation ENvironment (CAREN) system...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226426/physiological-mechanisms-for-stabilizing-the-limb-when-acting-against-physical-constraints
#7
P Senot, L Damm, M Tagliabue, J McIntyre, P Senot, L Damm, M Tagliabue, J McIntyre, P Senot, L Damm, M Tagliabue, J McIntyre
Smooth physical interaction with our environment, such as when working with tools, requires adaptability to unpredictable perturbations that can be achieved through impedance control of multi-joint limbs. Modulation of arm stiffness can be achieved either increasing co-contraction of antagonistic muscles or by increasing the gain of spinal reflex loops. According to the "automatic gain scaling" principle, the spinal reflex gain, as measured via the H-reflex, scales with muscle activation. A previous experiment from our labs suggested, however, that reflex gains might instead be scaled to the force exerted by the limb, perhaps as a means to counteract destabilizing external forces...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28224240/simulation-of-cell-substrate-traction-force-dynamics-in-response-to-soluble-factors
#8
Tao Liu
Finite element (FE) simulations of contractile responses of vascular muscular thin films (vMTFs) and endothelial cells resting on an array of microposts under stimulation of soluble factors were conducted in comparison with experimental measurements reported in the literature. Two types of constitutive models were employed in the simulations, i.e. smooth muscle cell type and non-smooth muscle cell type. The time histories of the effects of soluble factors were obtained via calibration against experimental measurements of contractile responses of tissues or cells...
February 21, 2017: Biomechanics and Modeling in Mechanobiology
https://www.readbyqxmd.com/read/28223172/a-simple-model-of-cardiac-muscle-for-multiscale-simulation-passive-mechanics-crossbridge-kinetics-and-calcium-regulation
#9
Fyodor A Syomin, Andrey K Tsaturyan
A simple model of cardiac muscle was designed for multiscale simulation of heart mechanics. Relaxed cardiac muscle was described as a transversally isotropic hyperelastic material. Active tension caused by actin-myosin crossbridges depends on the ensemble averaged strain of myosin heads bound to actin. Calcium activation was modeled by Ca(2+) binding to troponin-C. To account for the dependence of troponin affinity for Ca(2+) on myosin heads strongly bound to actin, the kinetics of troponin binding to Ca(2+) in the overlap zone of the thin and thick filaments and outside it were separated...
February 18, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28218814/mr-elastography-measurement-of-the-effect-of-passive-warmup-prior-to-eccentric-exercise-on-thigh-muscle-mechanical-properties
#10
Paul Kennedy, Lewis J Macgregor, Eric Barnhill, Curtis L Johnson, Michael Perrins, Angus Hunter, Colin Brown, Edwin J R van Beek, Neil Roberts
PURPOSE: To investigate the effect of warmup by application of the thermal agent Deep Heat (DH) on muscle mechanical properties using magnetic resonance elastography (MRE) at 3T before and after exercise-induced muscle damage (EIMD). MATERIALS AND METHODS: Twenty male participants performed an individualized protocol designed to induce EIMD in the quadriceps. DH was applied to the thigh in 50% of the participants before exercise. MRE, T2 -weighted MRI, maximal voluntary contraction (MVC), creatine kinase (CK) concentration, and muscle soreness were measured before and after the protocol to assess EIMD effects...
February 20, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28215990/neural-mechanisms-of-single-corrective-steps-evoked-in-the-standing-rabbit
#11
L-J Hsu, P V Zelenin, V F Lyalka, M G Vemula, G N Orlovsky, T G Deliagina
Single steps in different directions are often used for postural corrections. However, our knowledge about the neural mechanisms underlying their generation is scarce. This study was aimed to characterize the corrective steps generated in response to disturbances of the basic body configuration caused by forward, backward or outward displacement of the hindlimb, as well as to reveal location in the CNS of the corrective step generating mechanisms. Video recording of the motor response to translation of the supporting surface under the hindlimb along with contact forces and activity of back and limb muscles was performed in freely standing intact and in fixed postmammillary rabbits...
February 12, 2017: Neuroscience
https://www.readbyqxmd.com/read/28214267/a-japanese-male-with-a-novel-ano5-mutation-with-minimal-muscle-weakness-and-muscle-pain-till-his-late-fifties
#12
Masato Kadoya, Katsuhisa Ogata, Mikiya Suzuki, Yutaka Honma, Kazunari Momma, Kana Yatabe, Takuhisa Tamura, Kenichi Kaida, Naomasa Miyata, Ichizo Nishino, Ikuya Nonaka, Mitsuru Kawai
Limb girdle muscular dystrophy type 2L (LGMD2L) is an adult-onset slowly progressive muscular dystrophy associated with anoctamin 5 (ANO5) gene mutation, mainly reported from Northern and Central Europe. We report the case of a Japanese male patient with a novel homozygous mutation of c.2394dup, p.Arg799Thrfs in ANO5 gene, the second patient in the Asian population. He had had marked elevation of creatine kinase (CK) level for more than 10 years with minimal muscular symptoms consisting of muscle stiffness and occasional cramps, preceding the onset of proximal limb weakness...
January 18, 2017: Neuromuscular Disorders: NMD
https://www.readbyqxmd.com/read/28213864/electrical-stimulation-of-denervated-rat-skeletal-muscle-ameliorates-bone-fragility-and-muscle-loss-in-early-stage-disuse-musculoskeletal-atrophy
#13
Hiroyuki Tamaki, Kengo Yotani, Futoshi Ogita, Keishi Hayao, Kouki Nakagawa, Kazuhiro Sugawara, Hikari Kirimoto, Hideaki Onishi, Norikatsu Kasuga, Noriaki Yamamoto
We tested whether daily muscle electrical stimulation (ES) can ameliorate the decrease in cortical bone strength as well as muscle and bone geometric and material properties in the early stages of disuse musculoskeletal atrophy. 7-week-old male F344 rats were randomly divided into three groups: age-matched control group (Cont); a sciatic denervation group (DN); and a DN + direct electrical stimulation group (DN + ES). Denervated tibialis anterior (TA) muscle in the DN + ES group received ES with 16 mA at 10 Hz for 30 min/day, 6 days/week...
February 17, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/28210061/therapeutic-effects-of-massage-and-electrotherapy-on-muscle-tone-stiffness-and-muscle-contraction-following-gastrocnemius-muscle-fatigue
#14
Joong-San Wang
[Purpose] This study aimed to examine the effects of a combined intervention consisting of massage therapy and transcutaneous electrical nerve stimulation on gastrocnemius muscle fatigue, assessing whether the intervention improved muscle tone, stiffness, and muscle contraction. [Subjects and Methods] The subjects were 20 healthy males in their 20s who were equally divided into a transcutaneous electrical nerve stimulation group and a combined therapy group that received a combination of massage therapy and transcutaneous electrical nerve stimulation...
January 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28208087/morphomechanical-alterations-in-the-medial-gastrocnemius-muscle-in-patients-with-a-repaired-achilles-tendon-associations-with-outcome-measures
#15
Wei-Chen Peng, Yi-Ping Chang, Yuan-Hung Chao, S N Fu, Christer Rolf, Tiffany Tf Shih, Sheng-Chu Su, Hsing-Kuo Wang
BACKGROUND: Functional deficits are found in ankles that have sustained an Achilles rupture. This study sought to evaluate and compare the morphomechanical characteristics of the medial gastrocnemius muscle in the legs of participants within six months of a unilateral Achilles repair to determine any correlations between those characteristics and objective outcomes and self-reported functional levels. METHODS: Fifteen participants were assessed via measurements of muscle morphologies (fascicle length, pennation angle, and muscle thickness) in a resting state, the mechanical properties of the proximal aponeurosis of the medial gastrocnemius muscle, the pennation angle during ramping maximal voluntary isometric contractions (MVIC), the heel raise test, and the Taiwan Chinese version of the Lower Extremity Functional Scale (LEFS-TC) questionnaire...
February 8, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28207961/muscle-stiffness-of-posterior-lower-leg-in-runners-with-a-history-of-medial-tibial-stress-syndrome
#16
Junya Saeki, Masatoshi Nakamura, Sayaka Nakao, Kosuke Fujita, Ko Yanase, Noriaki Ichihashi
Previous history of medial tibial stress syndrome (MTSS) is a risk factor for MTSS relapse, which suggests that there might be some physical factors that are related to MTSS development in runners with a history of MTSS. The relationship between MTSS and muscle stiffness can be assessed in a cross-sectional study that measures muscle stiffness in subjects with a history of MTSS, who do not have pain at the time of measurement, and in those without a history of MTSS. The purpose of this study was to compare the shear elastic modulus, which is an index of muscle stiffness, of all posterior lower leg muscles of subjects with a history of MTSS and those with no history and investigate which muscles could be related to MTSS...
February 16, 2017: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/28207187/a-robust-method-to-generate-mechanically-anisotropic-vascular-smooth-muscle-cell-sheets-for-vascular-tissue-engineering
#17
Daniel E Backman, Bauer L LeSavage, Shivem B Shah, Joyce Y Wong
In arterial tissue engineering, mimicking native structure and mechanical properties is essential because compliance mismatch can lead to graft failure and further disease. With bottom-up tissue engineering approaches, designing tissue components with proper microscale mechanical properties is crucial to achieve the necessary macroscale properties in the final implant. This study develops a thermoresponsive cell culture platform for growing aligned vascular smooth muscle cell (VSMC) sheets by photografting N-isopropylacrylamide (NIPAAm) onto micropatterned poly(dimethysiloxane) (PDMS)...
February 16, 2017: Macromolecular Bioscience
https://www.readbyqxmd.com/read/28205264/the-influence-of-patellar-tendon-and-muscle-tendon-unit-stiffness-on-quadriceps-explosive-strength-in-man
#18
Garry J Massey, Thomas G Balshaw, Thomas M Maden-Wilkinson, Neale A Tillin, Jonathan P Folland
The influence of musculotendinous tissue stiffness on contractile rate of torque development (RTD) remains opaque. This study examined the relationships between both patellar tendon (PT) and vastus lateralis (VL) muscle-tendon unit (MTU) stiffness, and voluntary and evoked knee extension RTD. Fifty-two healthy untrained males completed duplicate laboratory sessions. Absolute and relative RTD was measured at 50 Nm/25%MVT increments from onset and sequentially during explosive voluntary and evoked octet (supramaximal stimulation: [8 pulses at 300 Hz]) isometric contractions...
February 15, 2017: Experimental Physiology
https://www.readbyqxmd.com/read/28202584/comparison-of-human-gastrocnemius-forces-predicted-by-hill-type-muscle-models-and-estimated-from-ultrasound-images
#19
Taylor J M Dick, Andrew A Biewener, James M Wakeling
Hill-type models are ubiquitous in the field of biomechanics, providing estimates of a muscle's force as a function of its activation state and its assumed force-length and force-velocity properties. However, despite their routine use, the accuracy with which Hill-type models predict the forces generated by muscles during submaximal, dynamic tasks remains largely unknown. This study compared human gastrocnemii forces predicted by Hill-type models to the forces estimated from ultrasound-based measures of tendon length changes and stiffness during cycling, over a range of loads and cadences...
February 15, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28199848/discoidin-domain-receptor-1-mediates-myosin-dependent-collagen-contraction
#20
Nuno M Coelho, Pamma D Arora, Sander van Putten, Stellar Boo, Petar Petrovic, Alyna Xue Lin, Boris Hinz, Christopher A McCulloch
Discoidin domain receptor 1 (DDR1) is a tyrosine kinase collagen adhesion receptor that mediates cell migration through association with non-muscle myosin IIA (NMIIA). Because DDR1 is implicated in cancer fibrosis, we hypothesized that DDR1 interacts with NMIIA to enable collagen compaction by traction forces. Mechanical splinting of rat dermal wounds increased DDR1 expression and collagen alignment. In periodontal ligament of DDR1 knockout mice, collagen mechanical reorganization was reduced >30%. Similarly, cultured cells with DDR1 knockdown or expressing kinase-deficient DDR1d showed 50% reduction of aligned collagen...
February 14, 2017: Cell Reports
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