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Premature ventricular contraction

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https://www.readbyqxmd.com/read/29759626/post-extrasystolic-potentiation-for-individualizing-care-of-premature-ventricular-contraction-induced-cardiomyopathy
#1
EDITORIAL
Siva K Mulpuru, Chance M Witt
No abstract text is available yet for this article.
November 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29759625/post-extrasystolic-potentiation-as-a-predictor-of-recovery-of-left-ventricular-dysfunction-after-radiofrequency-catheter-ablation
#2
Balaji Krishnan, Ashwini Sankar, Inder Anand, Selcuk Adabag, Jian-Ming Li, Edward O McFalls, David G Benditt, Kalyanam Shivkumar, Venkatakrishna N Tholakanahalli
OBJECTIVES: This study hypothesizes that post-extrasystolic potentiation reflects left ventricle contractile reserve and therefore may predict an improvement of premature ventricular contraction (PVC)-induced cardiomyopathy after PVC ablation. BACKGROUND: Post-extrasystolic potentiation is a physiologic phenomenon of blood pressure accentuation after a PVC beat. METHODS: We performed a retrospective study of patients with a PVC burden of ≥10% PVC/24 h and left ventricular ejection fraction (LVEF) of <50% who underwent successful ablation between January 1, 2009, to June 30, 2015...
November 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29759541/the-phenotypic-spectrum-of-a-mutation-hotspot-responsible-for-the-short-qt-syndrome
#3
Dan Hu, Yang Li, Jiancheng Zhang, Ryan Pfeiffer, Michael H Gollob, Jeff Healey, Daniel Toshio Harrell, Naomasa Makita, Haruhiko Abe, Yaxun Sun, Jihong Guo, Li Zhang, Ganxin Yan, Douglas Mah, Edward P Walsh, Harris B Leopold, Carla Giustetto, Fiorenzo Gaita, Agnieszka Zienciuk-Krajka, Andrea Mazzanti, Silvia G Priori, Charles Antzelevitch, Hector Barajas-Martinez
OBJECTIVES: This study sought to evaluate the phenotypic and functional expression of an apparent hotspot mutation associated with short QT syndrome (SQTS). BACKGROUND: SQTS is a rare channelopathy associated with a high risk of life-threatening arrhythmias and sudden cardiac death (SCD). METHODS: Probands diagnosed with SQTS and their family members were evaluated clinically and genetically. KCNH2 wild-type (WT) and mutant genes were transiently expressed in HEK293 cells, and currents were recorded using whole-cell patch clamp and action potential (AP) clamp techniques...
July 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29759092/cardiac-function-in-children-with-premature-ventricular-contractions-the-effect-of-omega-3-polyunsaturated-fatty-acid-supplementation
#4
Taliha Oner, Rahmi Ozdemir, Onder Doksöz, Dildar B Genc, Baris Guven, Savas Demirpence, Murat M Yilmazer, Yilmaz Yozgat, Timur Mese, Vedide Tavli
BACKGROUND: Premature ventricular contractions are accepted as benign in structurally normal hearts. However, reversible cardiomyopathy can sometimes develop. Omega-3 polyunsaturated fatty acids have anti-arrhythmic properties in animals and humans.AimWe evaluated left ventricular function in children with premature ventricular contractions with normal cardiac anatomy and assessed the impact of omega-3 fatty acid supplementation on left ventricular function in a prospective trial. METHODS: A total of 25 patients with premature ventricular contraction, with more than 2% premature ventricular contractions on 24-hour Holter electrocardiography, and 30 healthy patients were included into study...
May 15, 2018: Cardiology in the Young
https://www.readbyqxmd.com/read/29740701/characteristics-and-circadian-distribution-of-cardiac-arrhythmias-in-patients-with-heart-failure-and-sleep-disordered-breathing
#5
Hazem Omran, Thomas Bitter, Dieter Horstkotte, Olaf Oldenburg, Henrik Fox
BACKGROUND: Cardiac arrhythmias and sleep-disordered breathing (SDB) are common comorbidities in heart failure with reduced ejection fraction (HFrEF). However, understanding of the association between arrhythmias and SDB is poor. This study assessed the occurrence and circadian distribution of ventricular arrhythmias in HFrEF patients with and without SDB. METHODS: This retrospective analysis included HFrEF patients admitted for unattended overnight cardiorespiratory polygraphy and 24-h Holter-ECG recording...
May 8, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29737447/predicting-value-of-coupling-interval-variability-in-determining-the-origin-of-ventricular-premature-contractions-with-v3-transition
#6
Umut Celikyurt, Aysen Agir, Irem Karauzum, Kurtulus Karauzum, Tayfun Sahin, Ahmet Vural
PURPOSE: We aimed to investigate the predictive value of coupling interval variability (ΔCI) in determining the origin of idiopathic outflow tract ventricular tachycardia (OTVT) with V3 transition. METHODS: We reviewed data from 126 patients who underwent catheter ablation of OTVT between 2015 and 2018 at our institution. We identified 32 patients of successful OTVT ablation with a precordial transition at V3 derivation. The ΔCI (maximum - minimum CI) was measured...
May 8, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29736793/a-novel-imaging-finding-in-williams-syndrome-the-coral-sign
#7
Jeremy R Burt, Kimberly Beavers, Melissa Kendall, Michael Valente, Jorge A Garcia
A 16-year-old female, with a history of Williams syndrome, presented to our institution with a 2-week history of intermittent dizziness. Holter monitoring demonstrated occasional premature ventricular contractions with rare couplets and triplets as well as one short run of nonsustained ventricular tachycardia. Echocardiography revealed an abnormal and irregular left ventricular septum with multiple mobile, pedunculated muscular projections extending into the left ventricular cavity. Cardiac MR confirmed abnormally thickened trabeculations consisting of multiple parallel ridges of myocardium crossing the left ventricle...
May 7, 2018: Pediatric Cardiology
https://www.readbyqxmd.com/read/29731502/idiopathic-ventricular-premature-contraction-and-ventricular-tachycardia-distribution-of-the-origin-diagnostic-algorithm-and-catheter-ablation
#8
Yoshinori Kobayashi
Idiopathic ventricular premature contractions (VPCs), defined as VPCs in the absence of obvious structural heart disease, are one of the common types of arrhythmia in clinical practice. They are sometimes complicated with non-sustained ventricular tachycardia (VT), and/or sustained VT with almost same QRS morphology in 12 leads ECG. Idiopathic VT (IVT) commonly occurs by focal mechanisms and the origins are distributed in a variety of sites in both ventricles. In this article, the clinical characteristics of IVT/IVPCs, the diagnostic algorithm, and how to ablate them will be reviewed...
2018: Journal of Nippon Medical School, Nippon Ika Daigaku Zasshi
https://www.readbyqxmd.com/read/29718887/mode-of-initiation-and-clinical-significance-of-malignant-rapid-ventricular-arrhythmias-an-observational-study
#9
Li-Hong Luo, Jian-Ying Wang, Xin Chen, Jiafeng Lin, Ming Zhang
The purpose of this study was to explore the modes of initiation and clinical significance of malignant rapid ventricular arrhythmias (MRVAs).The surface 12-lead electrocardiogram (ECG) or sustained electrocardiomonitor graph was analyzed in 79 patients. All patients had at least 1 MRVA after being admitted to the hospital.According to the length of coupling interval of the initial premature ventricular contraction of MRVA, the modes of initiation of MRVA were divided into the following types: those initiated by premature ventricular contraction with short coupling intervals in patients with normal Q-T interval, and for which short-long-short sequences before MRVA precipitation were not observed; those initiated following short-long-short sequences, which were divided into 2 types according to the length of Q-T interval: a normal Q-T interval and a long Q-T interval...
May 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29716706/systolic-aortic-regurgitation-in-rheumatic-carditis-mechanistic-insight-by-doppler-echocardiography
#10
Jagdish C Mohan, Vishwas Mohan, Madhu Shukla, Arvind Sethi
BACKGROUND: Aortic regurgitation (AR) usually occurs in diastole in presence of an incompetent aortic valve. Systolic AR is a rare phenomenon occurring in patients with reduced left ventricular systolic pressure and atrial fibrillation or premature ventricular contractions. Its occurrence is a Doppler peculiarity and adds to the hemodynamic burden. AIM: Rheumatic carditis is often characterised by acute or subacute severe mitral regurgitation (MR) due to flail anterior mitral leaflet and elongated chords...
March 2018: Indian Heart Journal
https://www.readbyqxmd.com/read/29709244/scn5a-mutation-type-and-topology-are-associated-with-the-risk-of-ventricular-arrhythmia-by-sodium-channel-blockers
#11
Ahmad S Amin, Yolan J Reckman, Elena Arbelo, Anne M Spanjaart, Pieter G Postema, Rafik Tadros, Michael W Tanck, Maarten P Van den Berg, Arthur A M Wilde, Hanno L Tan
BACKGROUND: Ventricular fibrillation in patients with Brugada syndrome (BrS) is often initiated by premature ventricular contractions (PVCs). Presence of SCN5A mutation increases the risk of PVCs upon exposure to sodium channel blockers (SCB) in patients with baseline type-1 ECG. In patients without baseline type-1 ECG, however, the effect of SCN5A mutation on the risk of SCB-induced arrhythmia is unknown. We aimed to establish whether presence/absence, type, and topology of SCN5A mutation correlates with PVC occurrence during ajmaline infusion...
April 27, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29705553/dictionary-based-monitoring-of-premature-ventricular-contractions-an-ultra-low-cost-point-of-care-service
#12
S Chandra Bollepalli, S Sastry Challa, Laxminarayana Anumandla, Soumya Jana
While cardiovascular diseases (CVDs) are prevalent across economic strata, the economically disadvantaged population is disproportionately affected due to the high cost of traditional CVD management, involving consultations, testing and monitoring at medical facilities. Accordingly, developing an ultra-low-cost alternative, affordable even to groups at the bottom of the economic pyramid, has emerged as a societal imperative. Against this backdrop, we propose an inexpensive yet accurate home-based electrocardiogram (ECG) monitoring service...
April 25, 2018: Artificial Intelligence in Medicine
https://www.readbyqxmd.com/read/29678624/autonomic-cardiovascular-control-and-cardiac-arrhythmia-in-two-pregnant-women-with-hypertrophic-cardiomyopathy-insights-from-icd-monitoring
#13
Pietro Francia, Carmen Adduci, Beatrice Musumeci, Lorenzo Semprini, Francesca Palano, Luigi Zezza, Massimo Volpe, Camillo Autore
In women with hypertrophic cardiomyopathy (HCM), pregnancy prompts major changes in hemodynamic and cardiac autonomic function that may precipitate heart failure (HF) or increase the risk of cardiac arrhythmia. We report the clinical follow-up of two patients with non-obstructive HCM implanted with a cardioverter defibrillator (ICD) allowing for continuous analysis of heart rate (HR), heart rate variability (HRV) and cardiac arrhythmia throughout the entire course of pregnancy. Both patients experienced increased HR and decreased HRV from the early stages of pregnancy, which persisted until delivery...
April 17, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29676830/premature-ventricular-contraction-eliminated-by-radiofrequency-catheter-ablation-from-the-pulmonary-sinus-cusp-using-the-ventricular-potentials-in-the-summit-communicating-vein-as-a-guide-for-mapping
#14
Takashi Nakashima, Tomoki Kubota, Nobuhiro Takasugi, Masanori Kawasaki
No abstract text is available yet for this article.
April 20, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29671875/atrial-remodeling-and-ectopic-burden-in-recreational-athletes-implications-for-risk-of-atrial-fibrillation
#15
Adrian D Elliott, Rajiv Mahajan, Dominik Linz, Michael Stokes, Christian V Verdicchio, Melissa E Middeldorp, Andre La Gerche, Dennis H Lau, Prashanthan Sanders
BACKGROUND: Atrial remodeling, vagal tone and atrial ectopic triggers have been suggested to contribute to the increased incidence of atrial fibrillation (AF) in endurance athletes. How these parameters change with increased lifetime training hours is debated. HYPOTHESIS: We hypothesised that atrial remodeling occurs in proportion to total training history, thus contributing to the elevated risk of AF. METHODS: We recruited 99 recreational endurance athletes, subsequently grouped according to lifetime training hours, to undergo evaluation of atrial size, autonomic modulation and atrial ectopy...
April 19, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29667277/arrhythmic-manifestation-of-peripartum-cardiomyopathy-case-report
#16
Patryk Siedlecki, Małgorzata Kurpesa, Barbara Uznańska-Loch, Ewa Trzos, Jarosław Damian Kasprzak
We report a case of 26-year-old woman, with arrhythmic manifestation of peripartum cardiomyopathy with moderate heart failure. Ventricular arrhythmia recorded in ambulatory Holter ECG (premature ventricular contractions) was most severe during pregnancy, reduced when beta-blocker therapy was initiated and almost completely resolved after delivery. Then, 1 year after hospitalization in Cardiology Department, recurrence was observed with recorded short episode of nonsustained ventricular tachycardia.
April 17, 2018: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/29661525/a-preliminary-study-of-left-ventricular-rotational-mechanics-in-children-with-noncompaction-cardiomyopathy-do-they-influence-ventricular-function
#17
Hythem M Nawaytou, Andrea E Montero, Putri Yubbu, Renzo J C Calderón-Anyosa, Tomoyuki Sato, Matthew J O'Connor, Kelley D Miller, Philip C Ursell, Julien I E Hoffman, Anirban Banerjee
BACKGROUND: Current diagnostic criteria for noncompaction cardiomyopathy (NCC) lack specificity, and the disease lacks prognostic indicators. Reverse apical rotation (RAR) with abnormal rotation of the cardiac apex in the same clockwise direction as the base has been described in adults with NCC. The aim of this study was to test the hypothesis that RAR might differentiate between symptomatic NCC and benign hypertrabeculations and might be associated with ventricular dysfunction. METHODS: Echocardiograms from 28 children with NCC without cardiac malformations were prospectively compared with those from 29 age-matched normal control subjects...
April 13, 2018: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/29660447/the-usefulness-of-ventricular-pacing-during-atrial-fibrillation-ablation-in-a-persistent-left-superior-vena-cava-a-case-report
#18
Sen Matsumoto, Yasuharu Matsunaga-Lee, Nobutaka Masunaga, Yuzuru Takano
A 69-year-old woman with palpitations was referred to our hospital for a second session of atrial fibrillation (AF) catheter ablation. She had a history of AF ablation including pulmonary vein (PV) isolation and persistent left superior vena cava (PLSVC) isolation. Electrophysiologic studies showed the veno-atrial connections that had recovered. After PV isolation was performed, AF was induced by atrial premature contraction (APC) from the PLSVC, and AF storm occurred. During PLSVC isolation, AF was not induced by APC from the PLSVC...
April 13, 2018: Indian Pacing and Electrophysiology Journal
https://www.readbyqxmd.com/read/29628472/hcn4-overexpressing-mouse-embryonic-stem-cell-derived-cardiomyocytes-generate-a-new-rapid-rhythm-in-rats-with-bradycardia
#19
Yukihiro Saito, Kazufumi Nakamura, Masashi Yoshida, Hiroki Sugiyama, Makoto Takano, Satoshi Nagase, Hiroshi Morita, Kengo F Kusano, Hiroshi Ito
A biological pacemaker is expected to solve the persisting problems of an artificial cardiac pacemaker including short battery life, lead breaks, infection, and electromagnetic interference. We previously reported HCN4 overexpression enhances pacemaking ability of mouse embryonic stem cell-derived cardiomyocytes (mESC-CMs) in vitro. However, the effect of these cells on bradycardia in vivo has remained unclear. Therefore, we transplanted HCN4-overexpressing mESC-CMs into bradycardia model animals and investigated whether they could function as a biological pacemaker...
April 6, 2018: International Heart Journal
https://www.readbyqxmd.com/read/29627768/mitochondrial-ca-2-influx-contributes-to-arrhythmic-risk-in-nonischemic-cardiomyopathy
#20
An Xie, Zhen Song, Hong Liu, Anyu Zhou, Guangbin Shi, Qiongying Wang, Lianzhi Gu, Man Liu, Lai-Hua Xie, Zhilin Qu, Samuel C Dudley
BACKGROUND: Heart failure (HF) is associated with increased arrhythmia risk and triggered activity. Abnormal Ca2+ handling is thought to underlie triggered activity, and mitochondria participate in Ca2+ homeostasis. METHODS AND RESULTS: A model of nonischemic HF was induced in C57BL/6 mice by hypertension. Computer simulations were performed using a mouse ventricular myocyte model of HF. Isoproterenol-induced premature ventricular contractions and ventricular fibrillation were more prevalent in nonischemic HF mice than sham controls...
April 7, 2018: Journal of the American Heart Association
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