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Classification CKD

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https://www.readbyqxmd.com/read/28706750/a-reduced-set-of-features-for-chronic-kidney-disease-prediction
#1
Rajesh Misir, Malay Mitra, Ranjit Kumar Samanta
Chronic kidney disease (CKD) is one of the life-threatening diseases. Early detection and proper management are solicited for augmenting survivability. As per the UCI data set, there are 24 attributes for predicting CKD or non-CKD. At least there are 16 attributes need pathological investigations involving more resources, money, time, and uncertainties. The objective of this work is to explore whether we can predict CKD or non-CKD with reasonable accuracy using less number of features. An intelligent system development approach has been used in this study...
2017: Journal of Pathology Informatics
https://www.readbyqxmd.com/read/28693441/ckd-epi-creatinine-cystatin-c-glomerular-filtration-rate-estimation-equation-seems-more-suitable-for-chinese-patients-with-chronic-kidney-disease-than-other-equations
#2
Xiao-Hua Chi, Gui-Ping Li, Quan-Shi Wang, Yong-Shuai Qi, Kai Huang, Qian Zhang, Yao-Ming Xue
BACKGROUND: The aim of this study was to identify the optimal equation that accurately estimates the glomerular filtration rate (GFR) and the chronic kidney disease (CKD) stage in the Chinese population. METHODS: A total of 1296 Chinese patients aged 18-65 years old were enrolled in this study. The estimated GFRs (eGFRs) calculated separately by three Diet in Renal Disease (MDRD) equations and three Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations were compared with the reference GFR (rGFR) measured by the (99)Tc(m)-DTPA renal dynamic imaging method...
July 10, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28683079/validation-of-glomerular-filtration-rate-estimating-equations-in-chinese-children
#3
Ke Zheng, Mengchun Gong, Yan Qin, Hongmei Song, Ximin Shi, Yuan Wu, Fang Li, Xuemei Li
BACKGROUND: Glomerular filtration rate (GFR) is essential for renal function evaluation and classification of chronic kidney disease (CKD), while the reference method in children are cumbersome. In the Chinese children, there was no data about GFR measured through plasma or renal clearance of the exogenous markers, and therefore no validated GFR-estimating tools in this population. METHODS: We measured GFR with double-sample plasma clearance of 99mTc-DTPA (mGFR) in 87 hospitalized children with renal injury...
2017: PloS One
https://www.readbyqxmd.com/read/28678812/augmented-renal-clearance-is-not-a-risk-factor-for-mortality-in-enterobacteriaceae-bloodstream-infections-treated-with-appropriate-empiric-antimicrobials
#4
Jason P Burnham, Scott T Micek, Marin H Kollef
The main objective of the study was to assess whether augmented renal clearance was a risk factor for mortality in a cohort of patients with Enterobacteriaceae sepsis, severe sepsis, or septic shock that all received appropriate antimicrobial therapy within 12 hours. Using a retrospective cohort from Barnes-Jewish Hospital, a 1,250-bed teaching hospital, we collected data on individuals with Enterobacteriaceae sepsis, severe sepsis, and septic shock who received appropriate initial antimicrobial therapy between June 2009 and December 2013...
2017: PloS One
https://www.readbyqxmd.com/read/28626472/in-iga-nephropathy-glomerulosclerosis-is-associated-with-increased-urinary-cd80-excretion-and-urokinase-type-plasminogen-activator-receptor-positive-podocyturia
#5
Hernán Trimarchi, Romina Canzonieri, Amalia Schiel, Cristian Costales-Collaguazo, Aníbal Stern, Matías Paulero, Tatiana Rengel, José Andrews, Alejandro Iotti, Mariano Forrester, Fernando Lombi, Vanesa Pomeranz, Romina Iriarte, Alexis Muryan, Elsa Zotta
BACKGROUND: Podocyturia may determine the evolution to podocytopenia, glomerulosclerosis, and renal failure. According to the Oxford classification of IgA nephropathy (IgAN), the S1 lesion describes glomerulosclerosis. Urokinase-type plasminogen activator receptor (uPAR) participates in podocyte attachment, while CD80 increases in glomerulosclerosis. We measured uPAR-positive urinary podocytes and urinary CD80 (uCD80) in controls and in IgAN subjects with M1E0S0T0 and M1E0S1T0 Oxford scores to assess a potential association between podocyturia, inflammation, and glomerulosclerosis...
May 2017: Nephron Extra
https://www.readbyqxmd.com/read/28590145/hypertension-and-hyperglycemia-and-the-combination-thereof-enhances-the-incidence-of-chronic-kidney-disease-ckd-in-middle-aged-and-older-males
#6
Ryoma Michishita, Takuro Matsuda, Shotaro Kawakami, Satoshi Tanaka, Akira Kiyonaga, Hiroaki Tanaka, Natsumi Morito, Yasuki Higaki
AIM: Chronic kidney disease (CKD) may be an etiologic cause of aging, hypertension, diabetes mellitus (DM), and metabolic syndrome. However, the influence of these cardiovascular risk factors and their combination on the development of CKD remains controversial. This retrospective study evaluated the influence of cardiovascular risk factors and their combination on the incidence of CKD during a 6-year follow-up period in middle-aged and older males. METHODS: The subjects were 303 males without a history of cardiovascular disease, stroke, renal dysfunction, or dialysis treatment...
June 7, 2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28572883/impact-of-creatinine-methodology-on-glomerular-filtration-rate-estimation-in-diabetes
#7
Marijana Vučić Lovrenčić, Vanja Radišić Biljak, Kristina Blaslov, Sandra Božičević, Lea Smirčić Duvnjak
AIM: To evaluate the influence of creatinine methodology on the performance of chronic kidney disease (CKD)-Epidemiology Collaboration Group-calculated estimated glomerular filtration rate (CKD-EPI-eGFR) for CKD diagnosis/staging in a large cohort of diabetic patients. METHODS: Fasting blood samples were taken from diabetic patients attending our clinic for their regular annual examination, including laboratory measurement of serum creatinine and eGFR. RESULTS: Our results indicated an overall excellent agreement in CKD staging (kappa = 0...
May 15, 2017: World Journal of Diabetes
https://www.readbyqxmd.com/read/28453510/is-aspirin-associated-with-diabetic-retinopathy-the-singapore-epidemiology-of-eye-disease-seed-study
#8
Yuan Shi, Yih-Chung Tham, Ning Cheung, Jacqueline Chua, Gavin Tan, Paul Mitchell, Jie Jin Wang, Yin Bun Cheung, Ching-Yu Cheng, Tien Yin Wong
BACKGROUND/AIMS: To determine the association between aspirin use and diabetic retinopathy (DR) among persons with diabetes, in a population-based, cross-sectional study. METHODS: Subjects with diabetes aged >40 years from the Singapore Epidemiology of Eye Diseases Study were enrolled in this study. Retinal photographs were graded for DR according to the modified Airlie House classification system. Vision threatening diabetic retinopathy (VTDR) was defined as the presence of severe non-proliferative DR, or proliferative DR, or clinically significant macular oedema...
2017: PloS One
https://www.readbyqxmd.com/read/28407463/number-of-existing-permanent-teeth-is-associated-with-chronic-kidney-disease-in-the-elderly-korean-population
#9
Hye-Sun Shin
Background/Aims: The aim of this study was to assess the association between the number of existing permanent teeth and chronic kidney disease (CKD) in a representative sample of the elderly Korean population. Methods: A total of 2,519 subjects who participated in the Korean National Health and Nutrition Examination Survey were cross-sectionally examined. The number of existing permanent teeth was evaluated by clinical oral examination. CKD was defined based on definition and classification by Kidney Disease: Improving Global Outcomes (KDIGO) 2012 guidelines...
April 14, 2017: Korean Journal of Internal Medicine
https://www.readbyqxmd.com/read/28401396/applying-the-temporal-abstraction-technique-to-the-prediction-of-chronic-kidney-disease-progression
#10
Li-Chen Cheng, Ya-Han Hu, Shr-Han Chiou
Chronic kidney disease (CKD) has attracted considerable attention in the public health domain in recent years. Researchers have exerted considerable effort in attempting to identify critical factors that may affect the deterioration of CKD. In clinical practice, the physical conditions of CKD patients are regularly recorded. The data of CKD patients are recorded as a high-dimensional time-series. Therefore, how to analyze these time-series data for identifying the factors affecting CKD deterioration becomes an interesting topic...
May 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28392738/the-role-of-laboratory-testing-in-detection-and-classification-of-chronic-kidney-disease-national-recommendations
#11
REVIEW
Vanja Radišić Biljak, Lorena Honović, Jasminka Matica, Branka Krešić, Sanela Šimić Vojak
Chronic kidney disease (CKD) is a common clinical condition with significant adverse consequences for the patient and it is recognized as a significant public health problem. The role of laboratory medicine in diagnosis and management of CKD is of great importance: the diagnosis and staging are based on estimation of glomerular filtration rate (eGFR) and assessment of albuminuria (or proteinuria). Therefore, the joint working group of the Croatian society of medical biochemistry and laboratory medicine and Croatian chamber of medical biochemists for laboratory diagnostics in CKD issued this national recommendation regarding laboratory diagnostics of CKD...
February 15, 2017: Biochemia Medica: časopis Hrvatskoga Društva Medicinskih Biokemičara
https://www.readbyqxmd.com/read/28385646/independent-risk-factors-contributing-to-acute-kidney-injury-according-to-updated-valve-academic-research-consortium-2-criteria-after-transcatheter-aortic-valve-implantation-a-meta-analysis-and-meta-regression-of-13-studies
#12
Jiayang Wang, Wenyuan Yu, Ye Zhou, Yong Yang, Chenglong Li, Nan Liu, Xiaotong Hou, Longfei Wang
OBJECTIVES: This study aimed to examine the risk factors for transcatheter aortic valve implantation (TAVI)-associated acute kidney injury (AKI) according to the AKI definition from the Valve Academic Research Consortium-2 (VARC-2). SETTING: A meta-analysis. PARTICIPANTS: A total of 661 patients with post-TAVI AKI according to the VARC-2 definition and 2,012 controls were included in the meta-analysis. INTERVENTIONS: Patients undergoing TAVI were included in this meta-analysis...
December 21, 2016: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28384340/parathyroid-hormone-and-vitamin-d-are-associated-with-the-risk-of-metabolic-obesity-in-a-middle-aged-and-older-korean-population-with-preserved-renal-function-a-cross-sectional-study
#13
Jeonghoon Ha, Kwanhoon Jo, Dong-Jun Lim, Jung-Min Lee, Sang-Ah Chang, Moo I L Kang, Bong Yun Cha, Min-Hee Kim
BACKGROUND: In general, obesity is a major contributor to metabolic syndrome (MetS) and is associated with insulin resistance (IR). Metabolically obese but normal weight (MONW) individuals present metabolic abnormalities and features of MetS despite having a normal range of body mass index (BMI). In recent years, different subtypes of obesity have been introduced, including metabolically healthy obese (MHO) and metabolically obese obese (MOO). Also, it has been reported that vitamin D and parathyroid hormone (PTH) are possibly linked with MetS...
2017: PloS One
https://www.readbyqxmd.com/read/28371226/patterns-of-healthcare-encounters-experienced-by-patients-with-chronic-kidney-disease
#14
Janet L Welch, Julie Meek, Rebecca J Bartlett Ellis, Roberta Ambuehl, Brian S Decker
BACKGROUND: Patterns of healthcare encounters by patients in each stage of chronic kidney disease (CKD) have not been fully described. OBJECTIVE: This study describes patterns of healthcare resource use by patients with CKD. DESIGN: A retrospective descriptive design was used. PARTICIPANTS: Patients with Stages 1-5 CKD were identified in five existing de-identified healthcare insurance claims databases in the United States using codes from the International Classification of Diseases (ICD-9-CM)...
April 3, 2017: Journal of Renal Care
https://www.readbyqxmd.com/read/28365357/chronic-kidney-disease-is-more-common-in-locally-advanced-renal-cell-carcinoma
#15
Sumi Dey, Zachary Hamilton, Sabrina L Noyes, Conrad M Tobert, Jacob Keeley, Ithaar H Derweesh, Brian R Lane
OBJECTIVE: To retrospectively evaluate clinical predictors of chronic kidney disease (CKD) in renal cell carcinoma (RCC) patients to identify associations between patient- and tumor-specific factors with poorer renal function. CKD and RCC are interrelated, with 26%-44% of RCC patients having concomitant CKD at diagnosis. PATIENTS AND METHODS: Institutional registries from Spectrum Health and University of California, San Diego, were queried for preoperative glomerular filtration rate and proteinuria status before radical or partial nephrectomy...
March 30, 2017: Urology
https://www.readbyqxmd.com/read/28351191/acute-kidney-injury-after-percutaneous-nephrolithotomy-for-stones-in-solitary-kidneys
#16
Ahmed R El-Nahas, Diaa-Eldin Taha, Hussien M Ali, Ahmed M Elshal, Mohamed H Zahran, Nasr A El-Tabey, Ahmed M El-Assmy, Ahmed M Harraz, Hazem E Moawad, Mahmoud M Othman
OBJECTIVES: The aim of this study was to report the incidence, severity, outcome and risk factors of acute kidney injury (AKI) following percutaneous nephrolithotomy (PNL) in solitary kidneys. METHODS: The study included consecutive adult patients who underwent PNL for treatment of calculi in a solitary kidney between May 2012 and July 2015. Patients with congenital renal anomalies or with stages 4 and 5 chronic kidney disease (CKD) were excluded. Serum creatinine levels were measured the day before PNL, daily after PNL for 2-5 days and after 3 months...
April 2017: Scandinavian Journal of Urology
https://www.readbyqxmd.com/read/28332473/correlation-analysis-of-renal-ultrasound-elastography-and-clinical-and-pathological-changes-in-patients-with-chronic-kidney-disease%C3%A2
#17
Lingyan Peng, Tingting Zhong, Qiuling Fan, Yanjun Liu, Xuemei Wang, Lining Wang
OBJECTIVE: To analyze the correlations of renal tissue elastography with clinical biochemical indicators and pathological changes in patients with chronic kidney disease (CKD) as well as to explore the potential for renal tissue elastography as a new, noninvasive method for the dynamic monitoring of renal disease progression, efficacy assessment, and prognosis evaluation. METHODS: Patients admitted to the Department of Nephrology of the First Affiliated Hospital of China Medical University from August 2014 to January 2015 who had undergone renal biopsies were selected...
March 23, 2017: Clinical Nephrology
https://www.readbyqxmd.com/read/28320554/pregnancy-and-kidney-outcomes-in-patients-with-iga-nephropathy-a-cohort-study
#18
Xiaole Su, Jicheng Lv, Youxia Liu, Jinwei Wang, Xinxin Ma, Sufang Shi, Lijun Liu, Hong Zhang
BACKGROUND: The outcomes of pregnancy in immunoglobulin A nephropathy (IgAN) are controversial. This cohort study assessed the effects of pregnancy on kidney disease progression and risk factors for adverse pregnancy outcomes in patients with IgAN. STUDY DESIGN: A cohort study. SETTING & PARTICIPANTS: Women of child-bearing age with IgAN and minimum follow-up of 1 year after biopsy from December 2003 to September 2014. PREDICTORS: Pregnancy, treated as a time-dependent variable; baseline (at time of biopsy) estimated glomerular filtration rate (eGFR), proteinuria, blood pressure, and kidney pathology (Oxford MEST classification)...
March 17, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28289067/association-of-ckd-with-outcomes-among-patients-undergoing-transcatheter-aortic-valve-implantation
#19
Florian Lüders, Klaus Kaier, Gerrit Kaleschke, Katrin Gebauer, Matthias Meyborg, Nasser M Malyar, Eva Freisinger, Helmut Baumgartner, Holger Reinecke, Jochen Reinöhl
BACKGROUND AND OBJECTIVES: Despitethe multiple depicted associations of CKD with reduced cardiovascular and overall prognoses, the association of CKD with outcome of patients undergoing transcatheter aortic valve implantation has still not been well described. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: Data from all hospitalized patients who underwent transcatheter aortic valve implantation procedures between January 1, 2010 and December 31, 2013 in Germany were evaluated regarding influence of CKD, even in the earlier stages, on morbidity, in-hospital outcomes, and costs...
May 8, 2017: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/28283071/comparison-of-myocardial-damage-among-dogs-at-different-stages-of-clinical-leishmaniasis-and-dogs-with-idiopathic-chronic-kidney-disease
#20
COMPARATIVE STUDY
L Martínez-Hernández, D Casamian-Sorrosal, R Barrera-Chacón, J M Cuesta-Gerveno, S Belinchón-Lorenzo, L C Gómez Nieto, F J Duque-Carrasco
Canine leishmaniasis (CanL) is a systemic disease caused by the protozoan parasite Leishmania infantum. Myocarditis in CanL has been described previously in CanL by histopathological analysis of post-mortem specimens and by evaluation of cardiac troponin I (cTnI) levels. However, the degree of myocardial damage at different stages of CanL and the role that concurrent azotaemia plays in this myocardial injury are unknown. The aim of this study was to prospectively evaluate and compare the presence of myocardial injury in dogs at different stages of clinical CanL and in dogs with severe idiopathic chronic kidney disease (CKD) by measuring cTnI...
March 2017: Veterinary Journal
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