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Classification CKD

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https://www.readbyqxmd.com/read/27903598/the-ckd-classification-system-in-the-precision-medicine-era
#1
Yoshio N Hall, Jonathan Himmelfarb
No abstract text is available yet for this article.
November 30, 2016: Clinical Journal of the American Society of Nephrology: CJASN
https://www.readbyqxmd.com/read/27902586/neurological-psychological-and-cognitive-disorders-in-patients-with-chronic-kidney-disease-on-conservative-and-replacement-therapy
#2
Silvia Lai, Oriano Mecarelli, Patrizia Pulitano, Roberto Romanello, Leonardo Davi, Alessia Zarabla, Amalia Mariotti, Maria Carta, Giorgia Tasso, Luca Poli, Anna Paola Mitterhofer, Massimo Testorio, Nicla Frassetti, Paola Aceto, Alessandro Galani, Carlo Lai
Chronic kidney disease (CKD) is a highly prevalent condition in the world. Neurological, psychological, and cognitive disorders, related to CKD, could contribute to the morbidity, mortality, and poor quality of life of these patients. The aim of this study was to assess the neurological, psychological, and cognitive imbalance in patients with CKD on conservative and replacement therapy.Seventy-four clinically stable patients affected by CKD on conservative therapy, replacement therapy (hemodialysis (HD), peritoneal dialysis (PD)), or with kidney transplantation (KT) and 25 healthy controls (HC), matched for age and sex were enrolled...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27887750/chronic-kidney-disease
#3
REVIEW
Angela C Webster, Evi V Nagler, Rachael L Morton, Philip Masson
The definition and classification of chronic kidney disease (CKD) have evolved over time, but current international guidelines define this condition as decreased kidney function shown by glomerular filtration rate (GFR) of less than 60 mL/min per 1·73 m(2), or markers of kidney damage, or both, of at least 3 months duration, regardless of the underlying cause. Diabetes and hypertension are the main causes of CKD in all high-income and middle-income countries, and also in many low-income countries. Incidence, prevalence, and progression of CKD also vary within countries by ethnicity and social determinants of health, possibly through epigenetic influence...
November 22, 2016: Lancet
https://www.readbyqxmd.com/read/27861591/rule-mining-for-the-early-prediction-of-chronic-kidney-disease-based-on-metabolomics-and-multi-source-data
#4
Margaux Luck, Gildas Bertho, Mathilde Bateson, Alexandre Karras, Anastasia Yartseva, Eric Thervet, Cecilia Damon, Nicolas Pallet
1H Nuclear Magnetic Resonance (NMR)-based metabolic profiling is very promising for the diagnostic of the stages of chronic kidney disease (CKD). Because of the high dimension of NMR spectra datasets and the complex mixture of metabolites in biological samples, the identification of discriminant biomarkers of a disease is challenging. None of the widely used chemometric methods in NMR metabolomics performs a local exhaustive exploration of the data. We developed a descriptive and easily understandable approach that searches for discriminant local phenomena using an original exhaustive rule-mining algorithm in order to predict two groups of patients: 1) patients having low to mild CKD stages with no renal failure and 2) patients having moderate to established CKD stages with renal failure...
2016: PloS One
https://www.readbyqxmd.com/read/27834458/evaluation-of-padua-score-as-predictor-of-warm-ischemia-time-wit-during-laparoscopic-partial-nephrectomy-lpn
#5
Stefano Ricciardulli, Qiang Ding, Xu Zhang, Hongzhao Li, Baojun Wang, Guoqiang Yang, Xiyou Wang, Peng Zhang, Xin Ma, Alberto Breda
OBJECTIVE: To evaluate the efficacy of Preoperative Aspects and Dimension Used for an Anatomical (PADUA) classification in the prediction of Warm Ischemia Time (WIT) during Laparoscopic Partial Nephrectomy (LPN). METHODS: Single centre retrospective study on 402 patients who underwent LPN between January 2011 and October 2013. WIT was correlated with each characteristics of the PADUA classification. Univariate and multivariate analysis were used to evaluated the independent predictive risk factors of WIT >20 minutes...
November 18, 2016: Urologia
https://www.readbyqxmd.com/read/27819037/classification-of-kidney-transplant-recipients-using-a-combination-of-estimated-gfr-and-albuminuria-reflects-risk
#6
Christine A White, Ayub Akbari, Hari Talreja, Neha Lalani, Greg A Knoll
BACKGROUND: The 2012 Kidney Dialysis Initiative Global Outcomes chronic kidney disease (CKD) classification scheme subdivides stage 3 CKD and incorporates the urinary albumin-to-creatinine ratio (ACR). The aim of this study was to evaluate whether the novel scheme provides graded risk in kidney transplant recipients (KTRs). METHODS: Prevalent KTRs with available laboratory data were included. The primary outcome was a composite of doubling of serum creatinine, graft failure, or death...
August 2016: Transplantation Direct
https://www.readbyqxmd.com/read/27806690/vitamin-d-deficiency-may-predict-a-poorer-outcome-of-iga-nephropathy
#7
Xiao-Hua Li, Xin-Ping Huang, Ling Pan, Cheng-Yu Wang, Ju Qin, Feng-Wei Nong, Yu-Zhen Luo, Yue Wu, Yu-Ming Huang, Xi Peng, Zhen-Hua Yang, Yun-Hua Liao
BACKGROUND: Experimental studies showed that 25-hydroxy-vitamin D [25(OH)D] deficiency (defined as 25-hydroxy-vitamin D < 15 ng/ml) has been associated with CKD progression. Patients with IgA nephropathy have an exceptionally high rate of severe 25(OH)D deficiency; however, it is not known whether this deficiency is a risk factor for progression of IgA nephropathy. We conducted this study to investigate the relationship between the plasma level of 25(OH)D and certain clinical parameters and renal histologic lesions in the patients with IgA nephropathy, and to evaluate whether the 25(OH)D level could be a good prognostic marker for IgA nephropathy progression...
November 2, 2016: BMC Nephrology
https://www.readbyqxmd.com/read/27761670/the-association-between-urinary-liver-type-fatty-acid-binding-protein-and-chronic-kidney-disease-classification-in-hiv-infected-japanese-patients
#8
Shinichi Hikasa, Megumi Yasuda, Kyoko Hideta, Mai Kawakami, Satoshi Higasa, Akihiro Sawada, Tazuko Tokugawa, Takeshi Kimura
BACKGROUND: Renal dysfunction is recognized with increasing frequency among the noninfectious comorbidities associated with human immunodeficiency virus (HIV) infection. Urinary liver-type fatty acid-binding protein (L-FABP) has been shown to be a new biomarker to screen for not only tubulointerstitial damage but also kidney dysfunction. METHODS: We performed a cross-sectional study to determine the association between the urinary L-FABP and chronic kidney disease (CKD) among 77 HIV-infected Japanese patients by backward-stepwise multivariable logistic regression...
October 19, 2016: Clinical and Experimental Nephrology
https://www.readbyqxmd.com/read/27761632/comparative-risk-of-chronic-kidney-diseases-in-patients-with-urolithiasis-and-urological-interventions-a-longitudinal-population-based-study
#9
Shih-Yi Lin, Cheng-Li Lin, Chao-Hsiang Chang, His-Chin Wu, Wen-Chi Chen, I-Kuan Wang, Yao Lung Liu, Fung-Chang Sung, Yen-Jung Chang, Chia-Hung Kao
Large cohort studies on whether any association existed between urological interventions for urolithiasis and the development of CKD are lacking. From claims data of the National Health Insurance (NHI) program of Taiwan, we identified 54,433 patients newly diagnosed with urolithiasis during 1998-2010. For each case, four individuals without urolithiasis were randomly selected and frequency matched by age, sex, and diagnosis year. Both groups were followed up until the end of 2010. Incident CKD events were identified by the International Classification of Diseases, Ninth Revision (ICD-9) code in the NHI registration database...
October 19, 2016: Urolithiasis
https://www.readbyqxmd.com/read/27712637/survival-risk-factors-and-effect-of-treatment-in-101-patients-with-calciphylaxis
#10
James T McCarthy, Rokea A El-Azhary, Michelle T Patzelt, Amy L Weaver, Robert C Albright, Alina D Bridges, Paul L Claus, Mark D P Davis, John J Dillon, Ziad M El-Zoghby, LaTonya J Hickson, Rajiv Kumar, Robert D McBane, Kathleen A M McCarthy-Fruin, Marian T McEvoy, Mark R Pittelkow, David A Wetter, Amy W Williams
OBJECTIVE: To report on the survival and the associations of treatments upon survival of patients with calciphylaxis seen at a single center. PATIENTS AND METHODS: Using the International Classification of Diseases, Ninth Revision diagnosis code of 275.49 and the keyword "calciphylaxis" in the dismissal narrative, we retrospectively identified 101 patients with calciphylaxis seen at our institution between January 1, 1999, through September 20, 2014, using a predefined, consensus-developed classification scheme...
October 2016: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/27687445/incidence-of-acute-kidney-injury-after-elective-lower-limb-arthroplasty
#11
Aleksandra Nowicka, Thomas Selvaraj
STUDY OBJECTIVE: The aim of this study was to establish the incidence of acute kidney injury (AKI) in patients undergoing elective hip and knee arthroplasty. DESIGN: This was a retrospective cohort study. SETTING: The study was conducted in a district general hospital in the United Kingdom. PATIENTS: All patients undergoing elective hip and knee arthroplasty over a period of 6 months were included in the study. MEASUREMENT: Preoperative and postoperative serum creatinine concentration was recorded in all patients...
November 2016: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/27651468/albuminuria-and-masked-uncontrolled-hypertension-in-chronic-kidney-disease
#12
Rajiv Agarwal
BACKGROUND: Masked uncontrolled hypertension (MUCH) is associated with greater target organ damage such as left ventricular hypertrophy, increased arterial stiffness and albuminuria. Whether MUCH independently associates with greater cardiovascular end-organ damage or kidney damage is unclear. The objective of this study was to assess the strength of the relationship of MUCH (awake ambulatory blood pressure ≥135/85 mmHg and clinic blood pressure <140/90 mmHg) with target organ damage...
September 20, 2016: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/27641054/30-year-follow-up-study-of-iga-nephritis-in-a-southeast-asian-population-an-evaluation-of-the-oxford-histological-classification%C3%A2
#13
Keng Thye Woo, Cynthia C Lim, Marjorie W Y Foo, Hwai L Loh, Ai Zhen Jin, Yok Mooi Chin, Jason C J Choo, Puay Hoon Tan, Khuan Yew Chow, Lina H L Choong, Han Khim Tan, Kok Seng Wong, Choong Meng Chan
BACKGROUND: In 1985 we reported that 11% of a cohort of 151 patients with IgA nephritis (IgAN) had developed end-stage renal disease (ESRD) after a follow-up period of 5 years. 15 years later, 35% had developed ESRD. METHODS: We retrieved 125 stored renal biopsy paraffin blocks of the original cohort. From these, 102 patients were included in the present study and scored according to the Oxford classification as 21 specimens with less than 8 glomeruli were excluded and in 2 others, tissue samples were too tiny for a re-block...
November 2016: Clinical Nephrology
https://www.readbyqxmd.com/read/27638912/prevalence-incidence-and-prognosis-of-chronic-kidney-disease-classified-according-to-current-guidelines-a-large-retrospective-cohort-study-of-rheumatoid-arthritis-patients
#14
Takeshi Tokoroyama, Minoru Ando, Kyogo Setoguchi, Ken Tsuchiya, Kosaku Nitta
BACKGROUND: The prevalence, incidence and prognosis of chronic kidney disease (CKD) have not been fully understood in rheumatoid arthritis (RA) patients. METHODS: A retrospective cohort study was performed in 1077 RA patients from July 2004 to June 2014. CKD was defined as either proteinuria ≥1+ or estimated glomerular filtration rate (eGFR) <60 mL/min/1.73 m(2) or both, according to the current CKD classification with risk categories for future death, end-stage renal disease and cardiovascular disease...
September 16, 2016: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/27636771/cardiovascular-complications-in-chronic-dialysis-patients
#15
Thomas A Mavrakanas, David M Charytan
PURPOSE OF REVIEW: This review article focuses on the most significant cardiovascular complications in dialysis patients [sudden cardiac death (SCD), acute coronary syndromes, heart failure, and atrial fibrillation]. RECENT FINDINGS: Current and ongoing research aims to quantify the rate and pattern of significant arrhythmia in dialysis patients and to determine the predominant mechanism of SCD. Preliminary findings from these studies suggest a high rate of atrial fibrillation and that bradycardia and asystole may be more frequent than ventricular arrhythmia as a cause of sudden death...
November 2016: Current Opinion in Nephrology and Hypertension
https://www.readbyqxmd.com/read/27594744/chronic-kidney-disease-and-lipid-disorders
#16
Sandra Vegar Zubovic, Spomenka Kristic, Sabina Prevljak, Irmina Sefic Pasic
INTRODUCTION: Chronic kidney disease (CKD) represents a serious public health problem due to the increase in incidence and prevalence of this disease worldwide. Given the significant morbidity and mortality from cardiovascular disease (CVD) in the population of patients with CKD, and the fact that dyslipidemia itself is a risk factor for CVD, increases the importance of lipid metabolism study in patients with CKD. GOAL: Evaluate the lipid status of patients with chronic kidney disease...
June 2016: Medical Archives
https://www.readbyqxmd.com/read/27573728/heart-failure-and-kidney-dysfunction-epidemiology-mechanisms-and-management
#17
REVIEW
Joerg C Schefold, Gerasimos Filippatos, Gerd Hasenfuss, Stefan D Anker, Stephan von Haehling
Heart failure (HF) is a major health-care problem and the prognosis of affected patients is poor. HF often coexists with a number of comorbidities of which declining renal function is of particular importance. A loss of glomerular filtration rate, as in acute kidney injury (AKI) or chronic kidney disease (CKD), independently predicts mortality and accelerates the overall progression of cardiovascular disease and HF. Importantly, cardiac and renal diseases interact in a complex bidirectional and interdependent manner in both acute and chronic settings...
October 2016: Nature Reviews. Nephrology
https://www.readbyqxmd.com/read/27569452/main-renal-artery-clamping-with-or-without-renal-vein-clamping-during-robotic-partial-nephrectomy-for-clinical-t1-renal-masses-perioperative-and-long-term-functional-outcomes
#18
Kyle A Blum, David J Paulucci, Ronney Abaza, Daniel D Eun, Akshay Bhandari, Joan C Delto, Louis S Krane, Ashok K Hemal, Ketan K Badani
OBJECTIVE: To compare renal function outcome between a contemporary cohort of propensity score-matched patients undergoing main renal artery clamping (MAC) alone and those undergoing main renal artery clamping with renal vein clamping (MVAC) during robotic partial nephrectomy. MATERIALS AND METHODS: Patients with a solitary T1 renal mass undergoing robotic partial nephrectomy were propensity score-matched on American Society of Anesthesiologists score, RENAL Nephrometry score, tumor size, tumor laterality, and operating surgeon to provide 66 patients undergoing MAC and 66 patients undergoing MVAC for analysis...
August 26, 2016: Urology
https://www.readbyqxmd.com/read/27549908/trends-and-outcomes-of-chronic-kidney-disease-in-intensive-care-a-5-year-study
#19
Kylie Ngu, David Reid, Antony Tobin
BACKGROUND: The prevalence of CKD is increasing in Australia and is independently associated with a higher risk of hospitalisation and death. Australian data may be useful in guiding improved hospital management of this growing cohort of patients. AIM: To assess and compare the trends and outcomes for chronic kidney disease (CKD) patients requiring hospital and intensive care unit (ICU) admission at a tertiary referral hospital and state public hospitals. METHODS: We conducted a retrospective analysis of all acute care admissions to St Vincent's Hospital Melbourne and all Victorian public hospitals, using the Victorian Admitted Data Set (VAED), for the years 2010 to 2014 inclusive to determine CKD prevalence, demographic and outcome associations...
August 23, 2016: Internal Medicine Journal
https://www.readbyqxmd.com/read/27513312/chronic-kidney-disease-classification-in-systolic-blood-pressure-intervention-trial-comparison-using-modification-of-diet-in-renal-disease-and-ckd-epidemiology-collaboration-definitions
#20
Michael V Rocco, Arlene Chapman, Glenn M Chertow, Debbie Cohen, Jing Chen, Jeffrey A Cutler, Matthew J Diamond, Barry I Freedman, Amret Hawfield, Eric Judd, Anthony A Killeen, Kent Kirchner, Cora E Lewis, Nicholas M Pajewski, Barry M Wall, Jerry Yee
BACKGROUND: Interventional trials have used either the Modification of Diet in Renal Disease (MDRD) or chronic kidney disease (CKD)-Epidemiology Collaboration (CKD-EPI) equation for determination of estimated glomerular filtration rate (eGFR) to define whether participants have stages 3-5 CKD. The equation used to calculate eGFR may influence the number and characteristics of participants designated as having CKD. METHODS: We examined the classification of CKD at baseline using both equations in the Systolic Blood Pressure Intervention Trial (SPRINT)...
2016: American Journal of Nephrology
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