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https://www.readbyqxmd.com/read/28549302/partner-level-substance-use-associated-with-increased-sexual-risk-behaviors-among-men-who-have-sex-with-men-in-san-francisco-ca
#1
Robert E Brown, Caitlin Turner, Jaclyn Hern, Glenn-Milo Santos
BACKGROUND: Substance use is highly prevalent among men who have sex with men (MSM) and is associated with individual-level sexual risk behaviors. However, few studies have explored the relationship between substance use and HIV risk behaviors within partnerships. METHODS: We examined partner-level data between MSM participants (n=23) and their sexual partners (n=52). We used multivariable generalized estimating equations (GEE) logistic regression to assess the relationship between partner-level substance use during their last sexual encounter with each partner, and engaging in condomless anal intercourse (CAI) and serodiscordant CAI...
April 21, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28548649/aqueous-humor-endothelin-1-and-total-retinal-blood-flow-in-patients-with-non-proliferative-diabetic-retinopathy
#2
L-A Khuu, F Tayyari, J M Sivak, J G Flanagan, S Singer, M H Brent, D Huang, O Tan, C Hudson
PurposeThe purpose of this study was to determine the association between aqueous ET-1 levels and total retinal blood flow (TRBF) in patients with non-insulin-dependent type 2 diabetes mellitus (T2DM) and early non-proliferative diabetic retinopathy (NPDR).Patients and methodsA total of 15 age-matched controls and 15 T2DM patients with NPDR were recruited into the study. Aqueous humor (~80-120 μl) was collected before cataract surgery to measure the levels of ET-1 using suspension multiplex array technology...
May 26, 2017: Eye
https://www.readbyqxmd.com/read/28548454/corema-album-unbiased-dioecy-in-a-competitive-environment
#3
Ana Martins, Helena Freitas, Sofia Costa
1.Corema album is a dioecious coastal shrub. Dioecious plants growing in these resource-limited habitats may present spatial segregation of the sexes (SSS) or demographic biases because of the different reproductive effort between sexes. In these environments facilitation is a more common interaction between plants than competition. To assess factors determining the distribution of C. album male and female plants, we investigated the influence of habitat type (sand dunes and coastal woodlands), assessed the occurrence of SSS or demographic biases, and also a possible role of these shrubs as nurse plants...
May 26, 2017: Plant Biology
https://www.readbyqxmd.com/read/28538444/changes-in-cervical-alignment-after-multilevel-schwab-grade-ii-thoracolumbar-osteotomies-for-adult-spinal-deformity
#4
George M Ghobrial, Nathan H Lebwohl, Barth A Green, Joseph P Gjolaj
STUDY DESIGN: Retrospective Cohort OBJECTIVE.: To describe changes in cervical alignment(CA) and deformity (CD) after multilevel Schwab Grade II Osteotomies for adult spinal deformity (ASD). SUMMARY OF BACKGROUND DATA: Reciprocal cervical and global changes after ASD surgery have not been previous described in the setting of multilevel osteotomy. METHODS: Patients with long-segment (> 5 levels) fusion and osteotomy for ASD were radiographically evaluated...
May 19, 2017: Spine
https://www.readbyqxmd.com/read/28528907/widespread-biological-response-to-rapid-warming-on-the-antarctic-peninsula
#5
Matthew J Amesbury, Thomas P Roland, Jessica Royles, Dominic A Hodgson, Peter Convey, Howard Griffiths, Dan J Charman
Recent climate change on the Antarctic Peninsula is well documented [1-5], with warming, alongside increases in precipitation, wind strength, and melt season length [1, 6, 7], driving environmental change [8, 9]. However, meteorological records mostly began in the 1950s, and paleoenvironmental datasets that provide a longer-term context to recent climate change are limited in number and often from single sites [7] and/or discontinuous in time [10, 11]. Here we use moss bank cores from a 600-km transect from Green Island (65...
May 17, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28515697/trpa1-channels-modify-trpv1-mediated-current-responses-in-dorsal-root-ganglion-neurons
#6
Takayoshi Masuoka, Makiko Kudo, Yuka Yamashita, Junko Yoshida, Noriko Imaizumi, Ikunobu Muramatsu, Matomo Nishio, Takaharu Ishibashi
The transient receptor potential vanilloid 1 (TRPV1) channel is highly expressed in a subset of sensory neurons in the dorsal root ganglia (DRG) and trigeminal ganglia of experimental animals, responsible for nociception. Many researches have revealed that some TRPV1-positive neurons co-express the transient receptor potential ankyrin 1 (TRPA1) channel whose activities are closely modulated by TRPV1 channel. However, it is less investigated whether the activities of TRPV1 channel are modulated by the presence of TRPA1 channel in primary sensory neurons...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28511351/effects-of-various-fertilization-regimes-on-abundance-and-activity-of-anaerobic-ammonium-oxidation-bacteria-in-rice-wheat-cropping-systems-in-china
#7
Chao Gu, Huifang Zhou, Qichun Zhang, Yuhua Zhao, Hongjie Di, Yongchao Liang
Anaerobic ammonium oxidation (anammox) is an important process in many marine and paddy ecosystems. However, few studies have reported on the contribution to the nitrogen cycle of anammox and its dynamics in rice-wheat cropping systems with different fertilization regimes. Here, isotope tracing and molecular techniques were used to determine the potential rates of anammox and their association with bacterial abundance, diversity, and activity. Rice-wheat cropping systems at two sites in Jiangsu Province, China were selected and the treatments at each site were: 1) no fertilization (CK), 2) 100% chemical fertilization (CF), 3) pig manure compost plus 50% chemical fertilization (PMCF), and 4) straw plus 100% chemical fertilization (SRCF)...
May 12, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28508835/beneficial-influence-of-ellagic-acid-on-biochemical-indexes-associated-with-experimentally-induced-colon-carcinogenesis
#8
Umesalma Syed, Sudhandiran Ganapasam
OBJECTIVE: To elucidate the key biochemical indexes associated with 1, 2-dimethylhydrazine (DMH)-induced colon carcinogenesis and the modulatory efficacy of a dietary polyphenol, ellagic acid (EA). MATERIALS AND METHODS: Wistar rats were chosen to study objective, and were divided into 4 groups; Group 1-control rats; Group 2-rats received EA (60 mg/kg body weight/day, orally); rats in Group 3-induced with DMH (20 mg/kg body weight) subcutaneously for 15 weeks; DMH-induced Group 4 rats were initiated with EA treatment...
January 2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28505557/follow-up-of-patients-with-localized-breast-cancer-and-first-indicators-of-advanced-breast-cancer-recurrence-a-retrospective-study
#9
Julien Viot, Martin Bachour, Aurélia Meurisse, Xavier Pivot, Frédéric Fiteni
We conducted a retrospective study to assess the follow-up of patients with localized breast cancer and the first indicators of advanced breast cancer recurrence. All patients with advanced breast cancer recurrence treated between January 2010 and June 2016 in our institution were registered. Among these patients, 303 patients initially treated for early breast cancer with curative intent were identified. After initial curative treatment, follow-up involved the oncologist, the general practitioner and the gynecologist in 68...
May 12, 2017: Breast: Official Journal of the European Society of Mastology
https://www.readbyqxmd.com/read/28501631/plasmid-transfection-in-bovine-cells-optimization-using-a-realtime-monitoring-of-green-fluorescent-protein-and-effect-on-gene-reporter-assay
#10
J S Osorio, M Bionaz
Gene reporter technology (GRT) has opened several new avenues for monitoring biological events including the activation of transcription factors, which are central to the study of nutrigenomics. However, this technology relies heavily on the insertion of foreign plasmid DNA into the nuclei of cells (i.e., transfection), which can be very challenging and highly variable among cell types. The objective of this study was to investigate the optimal conditions to generate reliable GRT assay data on bovine immortalized cell lines, Madin Darby Bovine Kidney (MDBK) and bovine mammary epithelial alveolar (MACT) cells...
May 10, 2017: Gene
https://www.readbyqxmd.com/read/28501403/use-of-calcitriol-to-maintain-postpartum-blood-calcium-and-improve-immune-function-in-dairy-cows
#11
A Vieira-Neto, I R P Lima, F Lopes, C Lopera, R Zimpel, L D P Sinedino, K C Jeong, K Galvão, W W Thatcher, C D Nelson, J E P Santos
Our objectives were to determine the effects of an injectable formulation of calcitriol on mineral metabolism and immune function in postpartum Holstein cows that received an acidogenic diet prepartum to minimize hypocalcemia. In experiment 1, cows within 6 h of calving received calcitriol (0, 200, or 300 μg) to determine the dose needed to increase plasma concentrations of Ca; 300 μg was sufficient to sustain Ca for at least 3 d. In experiment 2, multiparous cows were assigned randomly to receive only vehicle (control, n = 25) or 300 μg of calcitriol (n = 25) subcutaneously within the first 6 h after calving...
May 10, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28494204/bio-and-toxic-elements-in-mushrooms-from-the-city-of-ume%C3%A3-and-outskirts-sweden
#12
Małgorzata Mędyk, Małgorzata Grembecka, Justyna Brzezicha-Cirocka, Jerzy Falandysz
Edible mushrooms (Albatrellus ovinus, Boletus edulis, Clitocybe odora, Gomphidius glutinosus, Leccinum scabrum, Leccinum versipelle, Lycoperdon perlatum, Suillus bovinus, Suillus luteus, and Xerocomus subtomentosus) collected from unpolluted areas of the city of Umeå and its outskirts in the northern part of Sweden were examined for contents of toxic metallic elements (Cd, Pb, and Ag) and essential macro- and microelements (K, Na, Ca, Mg, Cu, Fe, Mn, and Zn) using a validated method and a final measurement by flame atomic absorption spectroscopy (F-AAS)...
May 11, 2017: Journal of Environmental Science and Health. Part. B, Pesticides, Food Contaminants, and Agricultural Wastes
https://www.readbyqxmd.com/read/28493294/commercial-mineral-enhanced-dairy-by-products-as-sodium-replacers-antioxidants-and-calcium-fortifiers-in-sausages
#13
Anne Maren Engeloug, Gu Yi, Bjørg Egelandsdal, Anna Haug, Berit Nordvi
Sausages are perceived as high in Na and with a too high Na:K ratio. Frankfurter type sausages are regarded as important contributors of sodium in the diet and thereby of health risks. Surplus products from the dairy industry are various mineral powders enriched in either potassium, calcium, or phosphate and include various amounts of lactose. Sausages were produced at 3 sodium levels (equivalent to 13, 15, and 17 g NaCl/kg sausage) using 4 different milk ingredients (a dried skimmed milk powder, a calcium enriched milk powder, a potassium enriched powder, and a lactose enriched powder)...
May 10, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/28487155/midlife-risk-factor-exposure-and-incidence-of-cardiac-arrest-depending-on-cardiac-or-non-cardiac-origin
#14
Marcus Andreas Ohlsson, Linn Maria Anna Kennedy, Tord Juhlin, Olle Melander
OBJECTIVE: Little is known about midlife risk factors of future cardiac arrest. Our objective was to evaluate cardiovascular risk factors in midlife in relation to the risk of cardiac arrest (CA) of cardiac and non-cardiac origin later in life. METHODS: We cross-matched individuals of the population based Malmö Diet and Cancer study (n=30,447) with the local CA registry of the city of Malmö. Baseline exposures were related to incident CA. RESULTS: During a mean follow-up of 17...
May 3, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28486741/-implementation-of-a-vessel-sealing-device-in-a-centre-for-thyroid-surgery-risk-and-economic-profit
#15
Stephan Coerper, Wolfgang Stengl
Background This study investigated whether the use of the vessel sealing device LigaSure Small Jaw(™) is cost-effective and safe in thyroid surgery despite the high cost of material. Patients and Methods We analysed the results of 224 thyroid operations performed by the same surgeon in three time intervals. We included thyroidectomies and bilateral near-total resections (including Dunhill surgery). Minimally-invasive resections (MIVAT), unilateral resections or subtotal resections (remains > 2 ml), patients with recurrent goiter, operations with neck dissections and sternotomies were excluded...
May 9, 2017: Zentralblatt Für Chirurgie
https://www.readbyqxmd.com/read/28476984/optical-detection-of-ca-15-3-breast-cancer-antigen-using-cds-quantum-dot
#16
Venugopal Elakkiya, Mridula Prakash Menon, Devaraj Nataraj, Pullithadathil Biji, Rajendran Selvakumar
The present study focus on optical sensing of breast cancer antigen 15.3 (CA 15.3) using cadmium sulphide quantum dot (CdS-QD) in saline and serum samples spiked with antigen. The surface of CdS-QD was modified by cysteamine capping followed by tagging of CA 15.3 antibody. The samples were characterised using UV-visible absorption spectroscopy (UV-VIS Spectroscopy), Fourier transform infrared spectroscopy (FTIR), high-resolution transmission electron microscopy (HRTEM) attached with energy-dispersive X-ray spectroscopy, phase contrast inverted epi-fluorescence microscopy and photoluminescence (PL) spectrophotometry (EDS)...
April 2017: IET Nanobiotechnology
https://www.readbyqxmd.com/read/28475912/transport-of-multi-walled-carbon-nanotubes-stabilized-by-carboxymethyl-cellulose-and-starch-in-saturated-porous-media-influences-of-electrolyte-clay-and-humic-acid
#17
Bing Han, Wen Liu, Xiao Zhao, Zhengqing Cai, Dongye Zhao
This study investigated the transport behaviors of carboxymethyl cellulose (CMC) and starch stabilized multi-walled carbon nanotubes (MWNTs) through a saturated quartz sand column in the presence of electrolytes, model clays, and natural organic matter (humic acid) through column breakthrough experiments and model simulations. Both stabilizers, CMC and starch, greatly enhanced the breakthrough of MWNTs, with a full breakthrough plateau (C/C0) ranging from 0.69 to 0.90 at ionic strength from 0.3 to 10mM. Between the two stabilizers, CMC was more effective in resisting particle deposition, and thus CMC-stabilized MWNTs were more transportable through the medium...
May 2, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28473307/the-rsvp-project-factors-related-to-disengagement-from-human-immunodeficiency-virus-care-among-persons-in-san-francisco
#18
Susan Scheer, Miao-Jung Chen, Maree Kay Parisi, Maya Yoshida-Cervantes, Erin Antunez, Viva Delgado, Nicholas J Moss, Kate Buchacz
BACKGROUND: In the United States, an estimated two-thirds of persons with human immunodeficiency virus (HIV) infection do not achieve viral suppression, including those who have never engaged in HIV care and others who do not stay engaged in care. Persons with an unsuppressed HIV viral load might experience poor clinical outcomes and transmit HIV. OBJECTIVE: The goal of the Re-engaging Surveillance-identified Viremic Persons (RSVP) project in San Francisco, CA, was to use routine HIV surveillance databases to identify, contact, interview, and reengage in HIV care persons who appeared to be out of care because their last HIV viral load was unsuppressed...
May 4, 2017: JMIR Public Health and Surveillance
https://www.readbyqxmd.com/read/28471125/the-association-between-clinical-parameters-and-uterine-fibroid-size-in-patients-who-underwent-abdominal-myomectomy
#19
Mehmet Çınar, Rıfat Taner Aksoy, Ali İrfan Güzel, Aytekin Tokmak, Okan Yenicesu, Esma Sarıkaya, Özlem Evliyaoğlu
OBJECTIVES: To evaluate if there is an association between neutrophil lymphocyte ratio and tumor markers in patients with uterine fibroids. METHODS: A total of three hundred and fifty seven patients who operated for myomectomy were enrolled this retrospective case control study. Risk factors evaluated were; age, uterine fibroid type, body mass index (BMI), gravidity, parity, preoperative and postoperative hemoglobin difference, neutrophil/lymphocyte ratio (NLR), alpha fetoprotein (AFP), cancer antigen 125 (CA 125), cancer antigen 19-9 (CA 19-9), cancer antigen 15-3 (CA 15-3), carsino embryonic antigen (CEA) levels...
July 2016: Journal of Experimental Therapeutics & Oncology
https://www.readbyqxmd.com/read/28456516/identification-of-novel-1-indolyl-acetate-5-nitroimidazole-derivatives-of-combretastatin-a-4-as-potential-tubulin-polymerization-inhibitors
#20
Yong-Fang Yao, Zhong-Chang Wang, Song-Yu Wu, Qing-Fang Li, Chen-Yu, Xin-Yi Liang, Peng-Cheng Lv, Yong-Tao Duan, Hai-Liang Zhu
Microtubules are essential for the mitotic division of cells and have become an attractive target for anti-tumour drugs due to the increased incidence of cancer and significant mitosis rate of tumour cells. In this study, a total of six indole 1-position modified 1-indolyl acetate-5-nitroimidazole derivatives were designed, synthesized, and evaluated for their ability to inhibit tubulin polymerization caused by binding to the colchicine-binding site of tubulin. Among them, compound 3 displayed the best ability to inhibit tubulin polymerization; it also exhibited better anti-proliferative activities than colchicine against a panel of human cancer cells (with IC50 values ranging from 15 to 40 nM), especially HeLa cells (with IC50 values of 15 nM), based on the cellular cytotoxicity assay results...
April 26, 2017: Biochemical Pharmacology
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