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https://www.readbyqxmd.com/read/28805900/effects-of-dietary-tannins-on-total-and-extractable-nutrients-from-manure
#1
J J Halvorson, S L Kronberg, A E Hagerman
The effects of condensed tannins on N dynamics in ruminants have been a topic of research for some time, but much less work has focused on their impacts on other nutrients in manure. A 4 × 4 Latin square trial was used to determine if intake of sericea lespedeza (; SL; a condensed tannin source), at 0, 10, 20, or 40% of the diet (as-fed basis), would affect concentrations of nutrients in manure and patterns of total excretion when offered with alfalfa (; ALF) to sheep. With SL additions, average daily manure production increased linearly ( ≤ 0...
August 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28805195/-the-plasma-levels-and-diagnostic-utility-of-matrix-metalloproteinase-9-and-ca-125-in-cervical-cancer-patients
#2
Emilia Lubowicka, Ewa Gacuta, Monika Zajkowska, Edyta Katarzyna Głażewska, Andrzej Przylipiak, Lech Chrostek, Monika Zbucka-Krętowska, Sławomir Ławicki
Matrix metalloproteinases (MMPs) are a family of proteolytic enzymes, involved in the degradation of extracellular matrix components. The physiological function of MMP-9 is associated with regulation of immune processes, embryogenesis, reproduction and wound healing. MMP-9 also plays a critical role in tumor invasion, degrading the basement membrane, what is observed in different types of cancers: breast, gastrointestinal, and gynecological. AIM: The aim of this study was to investigate the plasma levels and diagnostic utility of MMP-9 and CA 125 in cervical cancer patients...
July 21, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28805161/eco-friendly-and-biocompatible-crosslinked-carboxymethylcellulose-hydrogels-as-adsorbents-for-the-removal-of-organic-dye-pollutants-for-environmental-applications
#3
Nádia S V Capanema, Alexandra A P Mansur, Herman S Mansur, Anderson C de Jesus, Sandhra M Carvalho, Poliane Chagas, Luiz C de Oliveira
In this study new eco-friendly hydrogel adsorbents were synthesized based on carboxymethylcellulose (CMC, degree of substitution DS = 0.7) chemically crosslinked with citric acid (CA) using a green process in aqueous solution and applied for the adsorption of methylene blue (MB). Spectroscopic analyses demonstrated the mechanism of crosslinking through the reaction of hydroxyl functional groups from CMC with CA. These CMC hydrogels showed very distinct morphological features dependent on the extension of crosslinking and their nanomechanical properties were drastically increased by approximately 300% after crosslinking with 20% CA (e...
August 13, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28804437/essential-and-toxic-metals-in-animal-bone-broths
#4
Der-Jen Hsu, Chia-Wei Lee, Wei-Choung Tsai, Yeh-Chung Chien
Background: This investigation examines the extraction of metals from animal bones into broth, and assesses whether bone broths are good sources of essential metals and the risks associated with the consumption of toxic metals. Method:Three sets of controlled experiments were performed to study the factors (cooking time, acidity, bone type and animal species) that influence metal extractions. Three types of animal bone broth-based foods were also tested. Results: Reducing the broth pH from 8.38 to 5.32 significantly (p < 0...
2017: Food & Nutrition Research
https://www.readbyqxmd.com/read/28803027/alizarin-yellow-r-ayr-as-compatible-stabilizer-for-miniemulsion-polymerization
#5
Zhang Zhenqian, Susanne Sihler, Ulrich Ziener
HYPOTHESIS: Many solid particles have been used in Pickering stabilized (mini)emulsions. Stabilizing "particles" can be also formed in situ e.g. by aggregation of dye molecules as reported recently. Among the dyes sodium 2-hydroxy-5-[(E)-(4-nitrophenyl)diazenyl]benzoate (Alizarin Yellow R, (AYR)) is one of the best stabilizers. It is assumed to act as sole stabilizer also in heterophase polymerizations and offers a great potential for applications. EXPERIMENTS: Aqueous solutions of AYR in varying concentrations (0...
August 3, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28801718/stentless-endoscopic-repair-of-congenital-choanal-atresia-is-it-enough-for-maintaining-choanal-patency
#6
Emel Çadallı Tatar, Bülent Öcal, Esra Doğan, Ömer Bayır, Cem Saka, Ali Özdek, Mehmet Hakan Korkmaz
The aim of choanal atresia (CA) surgery is to achieve bilateral nasal patency. Among the different methods of CA repair, the endoscopic transnasal approach has gained recent popularity with the advent of endoscopic instruments and techniques. This article describes our experience regarding CA repair that was done either using or not using a stent in different periods of time in our department. Between February 2006 and February 2016, a total of 29 patients aged 2 days-53 years underwent endoscopic transnasal CA repair...
August 11, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28801547/early-changes-in-plasma-dna-levels-of-mutant-kras-as-a-sensitive-marker-of-response-to-chemotherapy-in-pancreatic-cancer
#7
Marzia Del Re, Caterina Vivaldi, Eleonora Rofi, Enrico Vasile, Mario Miccoli, Chiara Caparello, Paolo Davide d'Arienzo, Lorenzo Fornaro, Alfredo Falcone, Romano Danesi
Pancreatic cancer (PDAC) is still lacking of reliable markers to monitor tumor response. CA 19-9 is the only biomarker approved, despite it has several limitations in sensitivity and specificity. Since mutations of KRAS occur in more than 90% of tumors, its detection in circulating free tumor DNA (cftDNA) could represent a biomarker to monitor chemotherapy response. Twenty-seven advanced PDAC patients given first-line 5-fluorouracil, irinotecan and oxaliplatin or gemcitabine and nab-paclitaxel were enrolled...
August 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28801321/massive-ascites-pelvic-mass-elevated-ca-125-and-weight-loss-think-outside-the-ovaries
#8
Jehan Khalid Mohammed Musleh, Mohammed Almulhem, Nourah Hasan Al Qahtani
A 44-year-old woman presented with 3 months' history of painless progressive abdominal distension and weight loss of more than 15 kg. Clinically a pelviabdominal mass with ascites was detected. CT scan of the pelvis and abdomen showed a subserosal leiomyoma with huge amount of ascites. Cancer Antigen (CA)-125 was 546 kU/L. Exploratory laparotomy with myomectomy was done and this was followed by dramatic improvement postoperatively.
August 11, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28801098/synthesis-and-in-vitro-evaluation-of-ca-2-channel-blockers-1-4-dihydropyridines-analogues-against-trypanosoma-cruzi-and-leishmania-amazonensis-sar-analysis
#9
Luiz A E Pollo, Milene H de Moraes, Júlia Cisilotto, Tânia B Creczynski-Pasa, Maique W Biavatti, Mario Steindel, Louis P Sandjo
Drugs containing the1,4-dihydropyridine (DHP) core have recently attracted attention concerning their antiparasitic effect against various species of Leishmania and Trypanosoma. This approach named drugs repositioning led to interesting results, which have prompted us to prepare 21 DHP's analogues. The 1,4-DHP scaffold was decorated with different function groups at tree points including the nitrogen atom (NH and N-phenyl), the aryl group attached to C-4 (various substituted aryl residues) and the carbon atoms 2 and 6 (bearing Ph or Me groups)...
August 8, 2017: Parasitology International
https://www.readbyqxmd.com/read/28800507/ultrasensitive-electrochemiluminescence-immunoassay-for-simultaneous-determination-of-ca125-and-ca15-3-tumor-markers-based-on-pamam-sulfanilic-acid-ru-bpy-3-2-and-pamam-cdte-cds-nanocomposite
#10
Bahareh Babamiri, Rahman Hallaj, Abdollah Salimi
A multiplex ultrasensitive electrochemiluminescence (ECL) immunoassay was developed for the simultaneous determination of two different tumor markers, cancer antigen 153 (CA 15-3) and cancer antigen 125 (CA 125) using polyamidoamine dendrimer-quantum dots (PAMAM-QDs) and PAMAM-sulfanilic acid-Ru(bpy)3(2+) as the signal probes and Fe3O4-SiO2 as a magnetic bead. The CdTe@CdS- QDs and Ru(bpy)3(2+) at the presence of tripropyl amine (TPA) as coreactant generate ECL at an applied voltage of + 1.2V (vs Ag/AgCl) in two different wavelengths 500 and 620nm, respectively...
July 28, 2017: Biosensors & Bioelectronics
https://www.readbyqxmd.com/read/28796899/plag1-immunohistochemistry-is-a-sensitive-marker-for-pleomorphic-adenoma-a-comparative-study-with-plag1-genetic-abnormalities
#11
Nora Katabi, Bin Xu, Achim A Jungbluth, Lei Zhang, Sung Yun Shao, Jason Lane, Ronald Ghossein, Cristina R Antonescu
AIMS: PLAG1 gene rearrangement is the most common genetic abnormality in pleomorphic adenoma (PA), resulting in overexpression of PLAG1 protein. PA and carcinoma ex pleomorphic adenoma (CA ex-PA) can mimic various benign and malignant salivary gland tumors. The aims of this study are to evaluate the sensitivity and specificity of PLAG1 immunohistochemistry (IHC) in the differential diagnosis of PA and CA ex-PA and to compare the PLAG1 immunohistochemical results to PLAG1 gene abnormalities as detected by fluorescence in situ hybridization (FISH)...
August 10, 2017: Histopathology
https://www.readbyqxmd.com/read/28796789/multiple-introductions-of-the-dengue-vector-aedes-aegypti-into-california
#12
Evlyn Pless, Andrea Gloria-Soria, Benjamin R Evans, Vicki Kramer, Bethany G Bolling, Walter J Tabachnick, Jeffrey R Powell
The yellow fever mosquito Aedes aegypti inhabits much of the tropical and subtropical world and is a primary vector of dengue, Zika, and chikungunya viruses. Breeding populations of A. aegypti were first reported in California (CA) in 2013. Initial genetic analyses using 12 microsatellites on collections from Northern CA in 2013 indicated the South Central US region as the likely source of the introduction. We expanded genetic analyses of CA A. aegypti by: (a) examining additional Northern CA samples and including samples from Southern CA, (b) including more southern US populations for comparison, and (c) genotyping a subset of samples at 15,698 SNPs...
August 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28795675/-clinical-application-of-abdominal-lifting-and-compression-cardiopulmonary-resuscitation-method-for-treatment-of-patients-with-cardiac-arrest
#13
Haishan Li, Liu Ji, Jingjing Wang
OBJECTIVE: To investigate the clinical application of rhythmic abdominal lifting and compression cardiopulmonary resuscitation (ALC-CPR) in cardiac arrest (CA) patients with conventional cardiopulmonary resuscitation (CPR) contraindication (chest rib fracture, chest trauma, etc.). METHODS: The clinical data of patients with CA in emergency department of Hefei Second People's Hospital from June 2015 to December 2016 were analyzed retrospectively, and the patients with weights 40-150 kg and CA≤20 minutes, and resuscitated with ALC-CPR were selected...
August 2017: Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
https://www.readbyqxmd.com/read/28795493/-molecularly-imprinted-chromatography-fails-to-distinguish-homeopatic-remedy-from-placebo
#14
Roman Kaliszan, Małgorzata Waszczuk-Jankowska, Danuta Siluk, Bartosz Wielgomas
It was sensation when Dr. J. Beneviste reported alleged experimental biological evidence of the water memory effect (E. Dayenas et al. Nature 333, 816-818, 1988; https://doi.org/10.1038/333816a0). These experiments have never been reproduced in controlled conditions, however. Instead, the hypothesis that water can be imprinted with the memory of past solutes was ruled out (J. Maddox et al. Nature 334, 287-290, 1988; https://doi.org/10.1038/334287a0). At present, so-called "molecular imprinting" is a technology of preparing polymer matrices as affinity-based analyte separation media (J...
August 10, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28791200/a-randomized-clinical-trial-of-vitamin-d3-cholecalciferol-in-ulcerative-colitis-patients-with-hypovitaminosis-d3
#15
Jagrati Mathur, Soe Naing, Paul Mills, David Limsui
AIM: To prospectively evaluate the effects of vitamin D3 on disease activity and quality of life in ulcerative colitis (UC) patients with hypovitaminosis D. METHODS: The study was a prospective double-blinded, randomized trial conducted at Community Regional Medical Center, Fresno, CA from 2012-2013. Patients with UC and a serum 25(OH)D level <30 ng/ml were eligible for the study. Enrolled subjects were randomized to receive either 2,000 IU or 4,000 IU of oral vitamin D3 daily for a total of 90 days...
2017: PeerJ
https://www.readbyqxmd.com/read/28791017/differentially-expressed-potassium-channels-are-associated-with-function-of-human-effector-memory-cd8-t-cells
#16
Ji Hyun Sim, Kyung Soo Kim, Hyoungjun Park, Kyung-Jin Kim, Haiyue Lin, Tae-Joo Kim, Hyun Mu Shin, Gwanghun Kim, Dong-Sup Lee, Chan-Wook Park, Dong Hun Lee, Insoo Kang, Sung Joon Kim, Chung-Hyun Cho, Junsang Doh, Hang-Rae Kim
The voltage-gated potassium channel, Kv1.3, and the Ca(2+)-activated potassium channel, KCa3.1, regulate membrane potentials in T cells, thereby controlling T cell activation and cytokine production. However, little is known about the expression and function of potassium channels in human effector memory (EM) CD8(+) T cells that can be further divided into functionally distinct subsets based on the expression of the interleukin (IL)-7 receptor alpha (IL-7Rα) chain. Herein, we investigated the functional expression and roles of Kv1...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28781889/evaluation-of-macular-and-peripapillary-vessel-flow-density-in-eyes-with-no-known-pathology-using-optical-coherence-tomography-angiography
#17
Muhammad Hassan, Mohammad Ali Sadiq, Muhammad Sohail Halim, Rubbia Afridi, Mohamed K Soliman, Salman Sarwar, Aniruddha Agarwal, Diana V Do, Quan Dong Nguyen, Yasir Jamal Sepah
PURPOSE: To assess normal vessel flow density (VFD) in macular and peripapillary regions of eyes with no known ocular pathology using optical coherence tomography angiography (OCTA). METHODS: AngioVue (Optovue, Fremont, CA, USA) was used to capture OCTA images. A 3 × 3 mm grid and a 4.5 × 4.5 mm grid was used to scan parafoveal and peripapillary regions, respectively. ReVue software was utilized to measure VFD in five sectors within the inner two circles of ETDRS grid in macular region and correlated to retinal thickness of same sectors...
2017: International Journal of Retina and Vitreous
https://www.readbyqxmd.com/read/28780474/protective-effect-of-p-coumaric-acid-against-1-2-dimethylhydrazine-induced-colonic-preneoplastic-lesions-in-experimental-rats
#18
Sharada H Sharma, David Raj Chellappan, Prabu Chinnaswamy, Sangeetha Nagarajan
Oxidative stress and gut microbial enzymes are intricately linked to the onset of colon carcinogenesis. Phytochemicals that modulate these two factors hold promise for the development of such agents as anticancer drugs. The present study evaluates the chemopreventive potential of p-coumaric acid (p-CA) - a phenolic acid in rats challenged with the colon specific procarcinogen DMH (1,2 di-methyl hydrazine). Rats were randomized into six groups (n=7/group). Group 1 (control); Group 2 (p-CA 200mg/kg b.w.); Group 3 (DMH 40mg/kg b...
August 3, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28772450/combining-bioactive-multifunctional-dental-composite-with-pamam-for-root-dentin-remineralization
#19
Shimeng Xiao, Kunneng Liang, Michael D Weir, Lei Cheng, Huaibing Liu, Xuedong Zhou, Yi Ding, Hockin H K Xu
Objectives. The objectives of this study were to: (1) develop a bioactive multifunctional composite (BMC) via nanoparticles of amorphous calcium phosphate (NACP), 2-methacryloyloxyethyl phosphorylcholine (MPC), dimethylaminohexadecyl methacrylate (DMAHDM) and nanoparticles of silver (NAg); and (2) investigate the effects of combined BMC + poly (amido amine) (PAMAM) on remineralization of demineralized root dentin in a cyclic artificial saliva/lactic acid environment for the first time. Methods. Root dentin specimens were prepared and demineralized with 37% phosphoric acid for 15 s...
January 22, 2017: Materials
https://www.readbyqxmd.com/read/28769950/transcriptome-analysis-of-calcium-and-hormone-related-gene-expressions-during-different-stages-of-peanut-pod-development
#20
Yan Li, Jingjing Meng, Sha Yang, Feng Guo, Jialei Zhang, Yun Geng, Li Cui, Shubo Wan, Xinguo Li
Peanut is one of the calciphilous plants. Calcium serves as a ubiquitous central hub in a large number of signaling pathways. In the field, free calcium ion (Ca(2+))-deficient soil can result in unfilled pods. Four pod stages were analyzed to determine the relationship between Ca(2+) excretion and pod development. Peanut shells showed Ca(2+) excretion at all four stages; however, both the embryo of Stage 4 (S4) and the red skin of Stage 3 (S3) showed Ca(2+) absorbance. These results showed that embryo and red skin of peanut need Ca(2+) during development...
2017: Frontiers in Plant Science
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