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https://www.readbyqxmd.com/read/28804870/effect-of-the-tool-to-reduce-inappropriate-medications-on-medication-communication-and-deprescribing
#1
Terri R Fried, Kristina M Niehoff, Richard L Street, Peter A Charpentier, Nallakkandi Rajeevan, Perry L Miller, Mary K Goldstein, John R O'Leary, Brenda T Fenton
OBJECTIVES: To examine the effect of the Tool to Reduce Inappropriate Medications (TRIM), a web tool linking an electronic health record (EHR) to a clinical decision support system, on medication communication and prescribing. DESIGN: Randomized clinical trial. SETTING: Primary care clinics at a Veterans Affairs Medical Center. PARTICIPANTS: Veterans aged 65 and older prescribed seven or more medications randomized to receipt of TRIM or usual care (N = 128)...
August 14, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28804603/towards-a-more-transparent-hta-process-in-poland-new-polish-hta-methodological-guidelines
#2
Krzysztof Lach, Michal Dziwisz, Cécile Rémuzat, Mondher Toumi
Introduction: Health technology assessment (HTA) in Poland supports reimbursement decisions via the Polish HTA Agency (AOTMiT), whose guidelines were updated in 2016. Methods: We identified key changes introduced by the update and, before guideline publication, analysed discrepancies between AOTMiT assessments and the submitting marketing authorisation holders (MAHs) to elucidate the context of the update. We compared the clarity and detail of the new guidelines versus those of the UK's National Institute for Health and Care Excellence (NICE)...
2017: Journal of Market Access & Health Policy
https://www.readbyqxmd.com/read/28803842/experimental-evidence-for-hybridization-of-closely-related-lineages-in-plasmodium-relictum
#3
Vaidas Palinauskas, Rasa Bernotienė, Rita Žiegytė, Staffan Bensch, Gediminas Valkiūnas
Over 50 avian Plasmodium species have been described. However, PCR-based information shows much broader diversity of genetic lineages in these parasites. This discrepancy indicates insufficient knowledge about taxonomic diversity and boundaries of a single species in avian Plasmodium species. In recent taxonomy, most of genetically closely related lineages that share the same morphology and development patterns are attributed to the same biological species, but there is no information if these lineages are able to cross...
August 10, 2017: Molecular and Biochemical Parasitology
https://www.readbyqxmd.com/read/28802452/connoted-hazard-and-perceived-importance-of-fluorescent-neon-and-standard-safety-colors
#4
O A Zielinska, C B Mayhorn, M S Wogalter
OBJECTIVE: The perceived hazard and rated importance of standard safety, fluorescent, and neon colors are investigated. BACKGROUND: Colors are used in warnings to enhance hazard communication. Red has consistently been rated as the highest in perceived hazard. Orange, yellow, and black are the next highest in connoted hazard; however, there is discrepancy in their ordering. Safety standards, such as ANSI Z535.1, also list colors to convey important information, but little research has examined the perceived importance of colors...
November 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/28801473/type-2-diabetes-in-the-real-world-the-elusive-nature-of-glycemic-control
#5
Steven V Edelman, William H Polonsky
Despite U.S. Food and Drug Administration (FDA) approval of over 40 new treatment options for type 2 diabetes since 2005, the latest data from the National Health and Nutrition Examination Survey show that the proportion of patients achieving glycated hemoglobin (HbA1c) <7.0% (<53 mmol/mol) remains around 50%, with a negligible decline between the periods 2003-2006 and 2011-2014. The Healthcare Effectiveness Data and Information Set reports even more alarming rates, with only about 40% and 30% of patients achieving HbA1c <7...
August 11, 2017: Diabetes Care
https://www.readbyqxmd.com/read/28799267/development-validation-and-reproducibility-of-a-food-frequency-questionnaire-to-measure-flavonoid-intake-in-older-australian-adults
#6
Katherine Kent, Karen E Charlton
AIM: To develop and assess the validity and reproducibility of a food frequency questionnaire (FFQ) to measure total flavonoid intake, and individual flavonoid subclasses, in older adults. METHODS: Retrospective analysis of flavonoid intake in older adults informed the development of a FFQ to measure flavonoid intake and determine the flavonoid subclasses consumed (anthocyanins, flavan-3-ols, flavones, flavonols and flavanones). Older adults (n = 42, mean age 75...
August 10, 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28795338/evaluation-of-patient-and-family-engagement-strategies-to-improve-medication-safety
#7
REVIEW
Julia M Kim, Catalina Suarez-Cuervo, Zackary Berger, Joy Lee, Jessica Gayleard, Carol Rosenberg, Natalia Nagy, Kristina Weeks, Sydney Dy
BACKGROUND: Patient and family engagement (PFE) is critical for patient safety. We systematically reviewed types of PFE strategies implemented and their impact on medication safety. METHODS: We searched MEDLINE, EMBASE, reference lists and websites to August 2016. Two investigators independently reviewed all abstracts and articles, and articles were additionally reviewed by two senior investigators for selection. One investigator abstracted data and two investigators reviewed the data for accuracy...
August 9, 2017: Patient
https://www.readbyqxmd.com/read/28791486/making-an-informed-decision-of-korean-cancer-patients-the-discrepancy-between-a-patient-s-recall-of-information-and-the-information-needed-for-acquisition-of-radiotherapy-informed-consent
#8
Hye Ran Lee, Chiyeon Lim, Hyong Geun Yun, Seung Hee Kang, Do Yeun Kim
INTRODUCTION: To give informed consent, a patient needs to sufficiently understand the information provided by a physician to decide among treatment options. Although shared decision-making is becoming an important aspect of patient-centered care, little is known about decision-making by cancer patients in Korea. OBJECTIVES: This study assessed Korean cancer patients' understanding of treatment goals and the need to obtain further information after a physician obtained informed consent for radiotherapy...
August 8, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28782976/the-observability-of-problem-behavior-and-its-relation-to-discrepancies-between-adolescents-self-report-and-parents-proxy-report-on-problem-behavior
#9
Marc Vierhaus, Jana Elisa Rueth, Arnold Lohaus
This study provides evidence regarding the relatedness of multi-informant agreement and perceived observability of internalizing and externalizing problem behaviors. Based on 2 distinct but comparable samples of children/adolescents (Sample 1: 58.2% female and mean age of 12.51 years; Sample 2: 56.4% female and mean age of 12.35 years) and their mothers, cross-sectional as well as longitudinal analyses were conducted. Although often suggested in the literature, the results of the study do not indicate that-in general-internalizing behavior is less observable than externalizing behavior...
August 7, 2017: Psychological Assessment
https://www.readbyqxmd.com/read/28780561/behaviour-change-interventions-for-the-management-of-raynaud-s-phenomenon-a-systematic-review-protocol
#10
Jo Daniels, John D Pauling, Christopher Eccelston
INTRODUCTION: Raynaud's phenomenon (RP) describes excessive peripheral vasospasm to cold exposure and/or emotional stress. RP episodes are associated with digital colour changes, pain and reduced quality of life. Pharmacological interventions are of low to moderate efficacy and often result in adverse effects such as facial flushing and headaches. Recommended lifestyle and behavioural interventions have not been evaluated. The objectives of the proposed systematic review are to assess the comparative safety and efficacy of behaviour change interventions for RP and identify what we can learn to inform future interventions...
August 4, 2017: BMJ Open
https://www.readbyqxmd.com/read/28780093/causal-effect-of-prolificacy-on-milk-yield-in-dairy-sheep-using-propensity-score
#11
Vera C Ferreira, David L Thomas, Bruno D Valente, Guilherme J M Rosa
In animal production, it is often important to investigate causal relationships among variables. The gold standard tool for such investigation is randomized experiments. However, randomized experiments may not always be feasible, possible, or cost effective or reflect real-world farm conditions. Sometimes it is necessary to infer effects from farm-recorded data. Inferring causal effects between variables from field data is challenging because the association between them may arise not only from the effect of one on another but also from confounding background factors...
August 2, 2017: Journal of Dairy Science
https://www.readbyqxmd.com/read/28780069/serine-protease-related-proteins-in-the-malaria-mosquito-anopheles-gambiae
#12
Xiaolong Cao, Mansi Gulati, Haobo Jiang
Insect serine proteases (SPs) and serine protease homologs (SPHs) participate in digestion, defense, development, and other physiological processes. In mosquitoes, some clip-domain SPs and SPHs (i.e. CLIPs) have been investigated for possible roles in antiparasitic responses. In a recent test aimed at improving quality of gene models in the Anopheles gambiae genome using RNA-seq data, we observed various discrepancies between gene models in AgamP4.5 and corresponding sequences selected from those modeled by Cufflinks, Trinity and Bridger...
August 2, 2017: Insect Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28777275/gait-deviations-in-children-with-osteogenesis-imperfecta-type-i
#13
Christina R Garman, Adam Graf, Joseph Krzak, Angela Caudill, Peter Smith, Gerald Harris
BACKGROUND: Osteogenesis imperfecta (OI) is a congenital connective tissue disorder often characterized by orthopaedic complications that impact normal gait. As such, mobility is of particular interest in the OI population as it is associated with multiple aspects of participation and quality of life. The purpose of the current study was to identify and describe common gait deviations in a large sample of individuals with type I OI and speculate the etiology with a goal of improving function...
August 2, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28774675/3-tesla-mri-beneficial-visualization-of-the-meniscofemoral-ligaments
#14
Johanna Ebrecht, Andrej Krasny, Dinah Maria Hartmann, Marcia Viviane Rückbeil, Thomas Ritz, Andreas Prescher
BACKGROUND: Recent investigations have confirmed an important stabilizing and protective function of the meniscofemoral ligaments (MFLs) to the knee joint and suggest a clinical relevance. Concerning their incidences, however, there have been discrepancies between data acquired from cadaveric studies and MRI data using 0.3- to 1.5-Tesla field strengths probably due to lower resolution. This study aims to investigate whether imaging with 3-Tesla magnetic resonance imaging (3-T MRI) is beneficial in gaining information regarding the ligaments' incidence, length, width and anatomic variation...
July 31, 2017: Knee
https://www.readbyqxmd.com/read/28772297/use-of-adult-patient-focus-groups-to-develop-the-initial-item-bank-for-a-cochlear-implant-quality-of-life-instrument
#15
Theodore R McRackan, Craig A Velozo, Meredith A Holcomb, Elizabeth L Camposeo, Jonathan L Hatch, Ted A Meyer, Paul R Lambert, Cathy L Melvin, Judy R Dubno
Importance: No instrument exists to assess quality of life (QOL) in adult cochlear implant (CI) users that has been developed and validated using accepted scientific standards. Objective: To develop a CI-specific QOL instrument for adults in accordance with the Patient Reported Outcomes Measurement Information System (PROMIS) guidelines. Design, Setting, and Participants: As required in the PROMIS guidelines, patient focus groups participated in creation of the initial item bank...
August 3, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28768610/behavior-change-techniques-in-physical-activity-ehealth-interventions-for-people-with-cardiovascular-disease-systematic-review
#16
Orlaith Mairead Duff, Deirdre Mj Walsh, Bróna A Furlong, Noel E O'Connor, Kieran A Moran, Catherine B Woods
BACKGROUND: Cardiovascular disease (CVD) is the leading cause of premature death and disability in Europe, accounting for 4 million deaths per year and costing the European Union economy almost €196 billion annually. There is strong evidence to suggest that exercise-based secondary rehabilitation programs can decrease the mortality risk and improve health among patients with CVD. Theory-informed use of behavior change techniques (BCTs) is important in the design of cardiac rehabilitation programs aimed at changing cardiovascular risk factors...
August 2, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28766395/dual-loyalties-everyday-ethical-problems-of-registered-nurses-and-physicians-in-combat-zones
#17
Kristina Lundberg, Sofia Kjellström, Lars Sandman
BACKGROUND: When healthcare personnel take part in military operations in combat zones, they experience ethical problems related to dual loyalties, that is, when they find themselves torn between expectations of doing caring and military tasks, respectively. AIM: This article aims to describe how Swedish healthcare personnel reason concerning everyday ethical problems related to dual loyalties between care and military tasks when undertaking healthcare in combat zones...
January 1, 2017: Nursing Ethics
https://www.readbyqxmd.com/read/28764821/investigating-the-role-of-near-infrared-spectroscopy-in-neonatal-medicine
#18
Kaylee M Evans, Lori B Rubarth
Near-infrared spectroscopy (NIRS) is a clinical tool that provides a bedside method of noninvasively measuring continuous, "real-time" oxygen consumption and monitoring for potential ischemia of somatic tissues, particularly the brain, kidneys, and intestine in neonates. Although the concept of NIRS seems promising, its implementation into clinical practice has been inconsistent for various reasons, including difficulty in interpreting regional oxygen saturation (rSO2), the wide variation in types of NIRS monitors and probes, the cost of new equipment, different monitoring modalities, large discrepancies in both intra- and interindividual use, a lack of defined universal normative values, and little to no data on outcomes or potentially harmful interventions made based on rSO2 readings...
July 1, 2017: Neonatal Network: NN
https://www.readbyqxmd.com/read/28764740/variation-of-stemness-markers-expression-in-tumor-nodules-from-synchronous-multi-focal-hepatocellular-carcinoma-an-immunohistochemical-study
#19
Regina Cheuk-Lam Lo, Carmen Oi-Ning Leung, Kenneth Siu-Ho Chok, Irene Oi-Lin Ng
BACKGROUND: Advancing knowledge in molecular pathogenesis of hepatocellular carcinoma (HCC) opens up new horizons in the diagnostic, prognostic and therapeutic perspectives. Assessing the expression of molecular targets prior to definitive treatment is gaining importance in clinical practice. In this study, we investigated the variation in expression pattern of stemness markers in synchronous multi-focal HCC. METHODS: In the first cohort, 21 liver explants with multi-focal HCC were examined for expression of stemness markers EpCAM, Sox9 and CK19 by immunohistochemistry (IHC)...
August 1, 2017: Diagnostic Pathology
https://www.readbyqxmd.com/read/28761452/comparison-of-manual-versus-automated-blood-pressure-measurement-in-intensive-care-unit-coronary-care-unit-and-emergency-room
#20
Ahmad Mirdamadi, Mostafa Etebari
BACKGROUND: Accuracy of blood pressure (BP) measurement in clinical settings is one of the most concerns despite of promotion in techniques for the measurement of BP. Our aim was to compare automated versus manual BP measurement in intensive care unit (ICU), coronary care unit (CCU), and emergency room patients. METHODS: Totally, 117 patients in ICU, CCU, and emergency department were registered in the study. Demographic information was recorded. The cardioset heart monitoring device was used for measuring BP and mercury sphygmomanometer with appropriate cuffs was used for manual method...
January 2017: ARYA Atherosclerosis
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