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Jill R. Siegel, Teresa J. Karcnik, Marcie B. Hertz, Hugo Gelmann, Stephen R. Baker
Secretory carcinoma of the breast is a rare but histologically distinct neoplasm that generally demonstrates an indolent growth pattern and a favorable prognosis. We present the mammographic, sonographic, and pathologic findings of a case of this tumor which initially presented as a palpable mass. Its appearance on breast ultrasound as a solid, well-circumscribed mass is not specific for this entity and, in fact, mimics benign entities such as fibradenoma, as well as other well-differentiated breast carcinomas...
May 1999: Breast Journal
A Ruibal, J Schneider, M C del Río, J Arias, M I Núñez, A Tejerina
In order to investigate the possible hormone-dependence of CD44v6 in human breast cancer, we assayed the concentrations of this isoform in the membrane fraction of 168 invasive ductal carcinomas (IDC) and in 26 normal breast tissue samples, 18 fibradenomas (FAD), 3 fibrocystic disease specimens (FD), 7 mucinous carcinomas and 4 medullary carcinomas using the ELISA method. The results were compared with those of the estrogen (ER) and progesterone (PR) receptors, pS2, tissue type plasminogen activator (t-PA), cathepsin D, epidermal growth factor receptor (EGFR) and c-erbB2/neu oncoprotein concentrations...
September 2000: Revista Española de Medicina Nuclear
F Parazzini, M Ferraroni, C La Vecchia, J A Baron, F Levi, S Franceschi, A Decarli
The relationship between smoking habits and the risk of benign breast disease (BBD) was analyzed using data from a case-control study conducted between 1981 and 1983 in the greater Milan area, Northern Italy. Cases (n = 288) were women with histologically confirmed BBD (203 dysplasia, 85 benign tumours) referred to the National Cancer Institute of Milan for biopsies. Controls were women (n = 291) seen on selected days for a cytological smear for cervical cancer in outpatient clinics of the same Institute. No consistent association emerged between various indicators of smoking habits (smoking status, number of cigarettes smoked per day, duration of smoking) and the risk of BBD...
June 1991: International Journal of Epidemiology
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