keyword
MENU ▼
Read by QxMD icon Read
search

molecular nutrition

keyword
https://www.readbyqxmd.com/read/29792949/srnaome-and-transcriptome-analysis-provide-insight-into-chilling-response-of-cowpea-pods
#1
Jinhua Zuo, Yunxiang Wang, Benzhong Zhu, Yunbo Luo, Qing Wang, Lipu Gao
Cowpea is an important horticultural crop in tropical and subtropical areas of Asia, Africa, and Latin America, as well as parts of southern Europe and Central and South America. Chilling injury is a common physiological hazard of cowpea in cold chain logistics which reduce the cowpea pod's nutritional quality and product value. However, the molecular mechanism involved in chilling injury remains unclear in cowpea pods. RNA-Seq and sRNA-Seq technologies were employed to decipher the miRNAs and mRNAs expression profiles and their regulatory networks in cowpea pods involved in chilling stress...
May 21, 2018: Gene
https://www.readbyqxmd.com/read/29789348/gestational-low-protein-intake-enhances-whole-kidney-mir-192-and-mir-200-family-expression-and-epithelial-to-mesenchymal-transition-in-rat-adult-male-offspring
#2
Letícia B Sene, Victor Hugo Gonçalves Rizzi, José A R Gontijo, Patricia A Boer
Studies have shown that adult offspring of mothers fed a protein-restricted diet during pregnancy present a pronounced reduction of nephron number associated with decreased fractional urinary sodium excretion and arterial hypertension. Additionally, recent advances in our understanding of the molecular pathways that govern the association of gestational nutritional restriction, intrauterine growth retardation and inflammation with impaired nephrogenesis, nephron underdosing and kidney fibrosis point to the epithelial to mesenchymal transition (EMT) as a common factor...
May 22, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29780400/led-lighting-modification-of-growth-metabolism-yield-and-flour-composition-in-wheat-by-spectral-quality-and-intensity
#3
István Monostori, Márk Heilmann, Gábor Kocsy, Marianna Rakszegi, Mohamed Ahres, Susan B Altenbach, Gabriella Szalai, Magda Pál, Dávid Toldi, Livia Simon-Sarkadi, Noémi Harnos, Gábor Galiba, Éva Darko
The use of light-emitting diode (LED) technology for plant cultivation under controlled environmental conditions can result in significant reductions in energy consumption. However, there is still a lack of detailed information on the lighting conditions required for optimal growth of different plant species and the effects of light intensity and spectral composition on plant metabolism and nutritional quality. In the present study, wheat plants were grown under six regimens designed to compare the effects of LED and conventional fluorescent lights on growth and development, leaf photosynthesis, thiol and amino acid metabolism as well as grain yield and flour quality of wheat...
2018: Frontiers in Plant Science
https://www.readbyqxmd.com/read/29779385/nutritional-available-seleno-amino-acid-derivative-antagonizes-cisplatin-induced-nephrotoxicity-through-inhibition-of-ros-mediated-signaling-pathways
#4
Xiaoling Li, Haobin Zhang, Leung Chan, Chang Liu, Tianfeng Chen
Discovery of nutritionally available agents that could antagonize cisplatin-induced nephrotoxicity is of great significance and clinical application potential. 3,3'-Diselenodipropionic acid (DSePA) is a seleno-amino acid derivative that exhibits strong antioxidant activity. Therefore, this study aimed to examine the protective effects of DSePA on cisplatin-induced nephrotoxicity as well as the molecular mechanisms. The results revealed that DSePA effectively inhibited cell apoptosis induced by cisplatin, through suppressing the caspases activation and PARP cleavage...
May 20, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29777486/physiological-and-quantitative-proteomic-analyses-unraveling-potassium-deficiency-stress-response-in-alligator-weed-alternanthera-philoxeroides-l-root
#5
Li-Qin Li, Lun Liu, Wei Zhuo, Qian Chen, Sheng Hu, Shuang Peng, Xi-Yao Wang, Yi-Fei Lu, Li-Ming Lu
Physiological and iTRAQ based proteomic analysis provided new insights into potassium deficiency stress response in alligator weed root. Alligator weed (Alternanthera philoxeroides) has a strong ability to adapt to potassium deficiency (LK) stress. Proteomic changes in response to this stress are largely unknown in alligator weed. In this study, we investigated physiological and molecular mechanisms under LK using isobaric tags for relative and absolute quantitation to characterize proteome-level changes in this plant...
May 18, 2018: Plant Molecular Biology
https://www.readbyqxmd.com/read/29775716/ovalbumin-as-a-carrier-to-significantly-enhance-the-aqueous-solubility-and-photostability-of-curcumin-interaction-and-binding-mechanism-study
#6
Yujia Liu, Yanxue Cai, Danyang Ying, Yinlian Fu, Yahong Xiong, Xueyi Le
Egg ovalbumin (OVA) as a macromolecular carrier has the potential to improve the solubility and stability of insolubility bioactive molecules, however, their binding behavior and the mechanism is still ambiguous. In this work, the curcumin was selected as the target to study the interaction and binding mechanism between curcumin and OVA by thermodynamic titration technique in combination with molecular dynamic simulation. The results suggested that the binding included two steps: first, curcumin molecule entered into the hydrophobic pocket of OVA by hydrophobic interaction; and second the interaction was enhanced via hydrogen bonds, resulting in static fluorescence quenching and secondary structural change of OVA...
May 15, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29775581/ep300-mediated-lysine-2-hydroxyisobutyrylation-regulates-glycolysis
#7
He Huang, Shuang Tang, Ming Ji, Zhanyun Tang, Miho Shimada, Xiaojing Liu, Shankang Qi, Jason W Locasale, Robert G Roeder, Yingming Zhao, Xiaoling Li
Lysine 2-hydroxyisobutyrylation (Khib) is an evolutionarily conserved and widespread histone mark like lysine acetylation (Kac). Here we report that EP300 functions as a lysine 2-hyroxyisobutyryltransferase to regulate glycolysis in response to nutritional cues. We discovered that EP300 differentially regulates Khib and Kac on distinct lysine sites, with only 6 of the 149 EP300-targeted Khib sites overlapping with the 693 EP300-targeted Kac sites. We demonstrate that diverse cellular proteins, particularly glycolytic enzymes, are targeted by EP300 for Khib, but not for Kac...
May 17, 2018: Molecular Cell
https://www.readbyqxmd.com/read/29772703/alpha-mangostin-improves-insulin-secretion-and-protects-ins-1-cells-from-streptozotocin-induced-damage
#8
Dahae Lee, Young-Mi Kim, Kiwon Jung, Young-Won Chin, Ki Sung Kang
Alpha (α)-mangostin, a yellow crystalline powder with a xanthone core structure, is isolated from mangosteen ( Garcinia mangostana ), which is a tropical fruit of great nutritional value. The aim of the present study was to investigate the anti-diabetic effects of α-mangostin and to elucidate the molecular mechanisms underlying its effect on pancreatic beta (β)-cell dysfunction. To assess the effects of α-mangostin on insulin production, rat pancreatic INS-1 cells were treated with non-toxic doses of α-mangostin (1⁻10 μM) and its impact on insulin signaling was examined by Western blotting...
May 16, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29767119/recent-advances-in-sturgeon-nutrition
#9
REVIEW
Silas S O Hung
Sturgeons are fish species of biological and economical importance, and most of them are endangered, vulnerable or rare because of their large size, late sexual maturity, long period between spawning, and longevity. These unique biological characteristics make them highly susceptible to overfishing, degradation of habitat and spawning ground, and contamination of water and sediments by pollutants. The objective of the current review is not to exhaustively include all studies on sturgeon nutrient requirements and utilizations conducted under laboratory conditions, but to critique some studies and update previous reviews...
September 2017: Animal nutrition
https://www.readbyqxmd.com/read/29764936/attachment-of-phosphorylcholine-residues-to-pneumococcal-teichoic-acids-and-modification-of-substitution-patterns-by-the-phosphorylcholine-esterase
#10
Franziska Waldow, Thomas P Kohler, Nathalie Heß, Dominik Schwudke, Sven Hammerschmidt, Nicolas Gisch
The bacterial lung pathogen Streptococcus pneumoniae has a unique nutritional requirement for exogenous choline and attaches phosphorylcholine ( P -Cho) residues to the Gal pN Ac moieties of its teichoic acids (TAs) in its cell wall. Two phosphorylcholine transferases, LicD1 and LicD2, mediate the attachment of P -Cho to the O -6 positions of the two Gal pN Ac residues present in each repeating unit of pneumococcal TAs (pnTAs), of which only LicD1 has been determined to be essential. At the molecular level, the specificity of the P -Cho attachment to pnTAs by LicD1 and LicD2 remains still elusive...
May 15, 2018: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/29762384/microbial-metabolism-in-the-mammalian-gut-molecular-mechanisms-and-clinical-implications
#11
Anne Hall, James Versalovic
Human intestinal microbes participate actively at the interface of diet, nutrition, and overall health status. These biodiverse communities of microorganisms have a broader metabolic repertoire compared with their host, and they are able to synthesize and degrade substrates that would be otherwise unavailable. In recent years, we have recognized that healthy microbial communities are important for energy harvest and the regulation of body systems outside the digestive tract. Microbial dysbiosis, however, has been implicated in a number of human disorders, including obesity and inflammation...
June 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29762372/metabolic-impacts-of-maltase-deficiencies
#12
Buford L Nichols, Susan S Baker, Roberto Quezada-Calvillo
The mucosal maltase enzymes are characterized by an activity that produces glucose from linear glucose polymers, assayed with the disaccharide maltose. The related enzyme isomaltase produces glucose from branched glucose polymers, assayed with palatinose. Maltase and isomaltase activities are part of the 4 disaccharidases assayed from clinical duodenal biopsy homogenates. The reported maltase activities are more difficult to interpret than lactase or sucrase activities because both the sucrase-isomaltase and maltase-glucoamylase proteins have overlapping maltase activities...
June 2018: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29760813/protective-and-restorative-effects-of-nutrients-and-phytochemicals
#13
REVIEW
Tania Rescigno, Mario F Tecce, Anna Capasso
Intoroduction: Dietary intake fundamentally provides reintegration of energy and essential nutrients to human organisms. However, its qualitative and quantitative composition strongly affects individual's health, possibly being either a preventive or a risk factor. It was shown that nutritional status resulting from long-term exposition to specific diet formulations can outstandingly reduce incidences of most common and most important diseases of the developed world, such as cardiovascular and neoplastic diseases...
2018: Open Biochemistry Journal
https://www.readbyqxmd.com/read/29756447/electrochemical-methodologies-for-the-detection-of-pathogens
#14
Mandana Amiri, Abolfazl Bezaatpour, Hamed Jafari, Rabah Boukherroub, Sabine Szunerits
Bacterial infections remain of the principal causes of morbidity and mortality worldwide. The number of death due to infections is declining every year by only 1% with a forecast of 13 million deaths in 2050. Among the 1400 recognized human pathogens, the majority of infectious diseases is caused by just a few, about 20 pathogens only. While the development of vaccinations and novel anti-bacterial drugs and treatments are at the forefront of research, and strongly financially supported by policy makers, another manner to limit and control infectious outbreaks is targeting the development and implementation of early warning systems, which indicate qualitatively and quantitatively the presence of a pathogen...
May 14, 2018: ACS Sensors
https://www.readbyqxmd.com/read/29753745/1-%C3%AE-25-dihydroxyvitamin-d-3-potentiates-avian-osteoclast-activation-by-increasing-the-formation-of-zipper-like-structure-via-src-rac1-signaling
#15
Dong Wang, Jian-Hong Gu, Ling-Ling Feng, Xi-Shuai Tong, Rui-Long Song, Hong-Yan Zhao, Jian-Chun Bian, Xue-Zhong Liu, Yan Yuan, Zong-Ping Liu
Avian bone metabolism diseases affect the development and production of chickens, and many of these diseases can be prevented and controlled by balanced nutrition and hormone medicine. The steroid hormone 1α,25-dihydroxyvitamin D3 plays a key role in maintaining the balance of avian bone metabolism. Clinically, 1α,25-(OH)2 D3 has been used to treat several bone diseases. Although several previous studies have investigated the effects of 1α,25-(OH)2 D3 on osteoclastogenesis, the mechanisms underpinning osteoclast (OC) activity remain largely unknown...
May 10, 2018: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/29753631/non-mycorrhizal-plants-the-exceptions-that-prove-the-rule
#16
REVIEW
Marco Cosme, Ivan Fernández, Marcel G A Van der Heijden, Corné M J Pieterse
The widespread symbiotic interaction between plants and arbuscular mycorrhizal (AM) fungi relies on a complex molecular dialog with reciprocal benefits in terms of nutrition, growth, and protection. Approximately 29% of all vascular plant species do not host AM symbiosis, including major crops. Under certain conditions, however, presumed non-host plants can become colonized by AM fungi and develop rudimentary AM (RAM) phenotypes. Here we zoom in on the mustard family (Brassicaceae), which harbors AM hosts, non-hosts, and presumed non-host species such as Arabidopsis thaliana, for which conditional RAM colonization has been described...
May 9, 2018: Trends in Plant Science
https://www.readbyqxmd.com/read/29750520/silencing-of-tt8-and-hb12-affects-nutritional-profiles-and-in-vitro-gas-production-relating-to-molecular-structures-of-alfalfa-medicago-sativa-plants
#17
Yaogeng Lei, Abdelali Hannoufa, Luciana Louzada Prates, Haitao Shi, Yuxi Wang, Bill Biligetu, David Christensen, Peiqiang Yu
The objective of this study was to investigate the effects of silencing TT8 and HB12 genes on the nutritive profiles and in vitro gas production of alfalfa relating to spectral molecular structures of alfalfa. TT8-silenced (TT8i, n=5) and HB12-silenced (HB12i, n=11) alfalfa were generated by RNA interference (RNAi), and were grown with non-transgenic control (NT, n=4) in a greenhouse. Alfalfa plants were harvested at early-to-mid vegetative stage. Samples were analyzed for chemical compositions, CNCPS fractions and in vitro gas production...
May 11, 2018: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29748652/the-contribution-of-swiss-scientists-to-the-assessment-of-energy-metabolism
#18
REVIEW
Jean-Pierre Montani, Yves Schutz, Abdul G Dulloo
Although Switzerland is considered a small country, it has its share in discoveries, inventions and developments for the assessment of energy metabolism. This includes seminal contributions to respiratory and metabolic physiology and to devices for measuring energy expenditure by direct and indirect calorimetry in vivo in humans and small animals (as well as in vitro in organs/tissues), for the purpose of evaluating the basic nutritional requirements. A strong momentum came during World War II when it was necessary to evaluate the energy requirements of soldiers protecting the country by assessing their energy expenditure, as well as to determine the nutritional needs of the Swiss civil population in time of war when food rationing was necessary to ensure national neutrality and independence...
May 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29746817/arginine-inhibits-the-malignant-transformation-induced-by-interferon-gamma-through-the-nf-%C3%AE%C2%BAb-gcn2-eif2%C3%AE-signaling-pathway-in-mammary-epithelial-cells-in-vitro-and-in-vivo
#19
Wenbo Ren, Yang Li, Xiaojing Xia, Wenfei Guo, Taiyu Zhai, Yuting Jin, Yanyi Che, Haidi Gao, Xiumei Duan, Tinghao Huang, Jing Huang, Liancheng Lei
Breast cancer is the most common female malignant tumors in the world. It seriously affects women's physical and mental health and the leading cause of cancer death among women. Our previous study demonstrated that diet-derived IFN-γ promoted the malignant transformation of primary bovine mammary epithelial cells by accelerating arginine depletion. The current study aimed to explore whether arginine addition could inhibit the degree of malignant transformation and its molecular mechanism. The results indicate that arginine addition could alleviate the malignant transformation of mammary epithelial cells induced by IFN-γ, including reducing cell proliferation, cell migration and colony formation, through the NF-κB-GCN2/eIF2α pathway...
May 7, 2018: Experimental Cell Research
https://www.readbyqxmd.com/read/29746484/identification-of-candidate-genes-for-gelatinization-temperature-gel-consistency-and-pericarp-color-by-gwas-in-rice-based-on-slaf-sequencing
#20
Xinghai Yang, Xiuzhong Xia, Yu Zeng, Baoxuan Nong, Zongqiong Zhang, Yanyan Wu, Faqian Xiong, Yuexiong Zhang, Haifu Liang, Guofu Deng, Danting Li
Rice is an important cereal in the world. The study of the genetic basis of important agronomic traits in rice landraces and identification of genes will facilitate the breed improvement. Gelatinization temperature (GT), gel consistency (GC) and pericarp color (PC) are important indices of rice cooking and eating quality evaluation and potential nutritional importance, which attract wide attentions in the application of genetic and breeding. To dissect the genetic basis of GT, GC and PC, a total of 419 rice landraces core germplasm collections consisting of 330 indica lines, 78 japonica lines and 11 uncertain varieties were planted, collected, then GT, GC, PC were measured for two years, and sequenced using specific-locus amplified fragment sequencing (SLAF-seq) technology...
2018: PloS One
keyword
keyword
23358
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"