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Ventricular septal defect

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https://www.readbyqxmd.com/read/28211263/increased-regurgitant-flow-causes-endocardial-cushion-defects-in-an-avian-embryonic-model-of-congenital-heart-disease
#1
Stephanie M Ford, Matthew T McPheeters, Yves T Wang, Pei Ma, Shi Gu, James Strainic, Christopher Snyder, Andrew M Rollins, Michiko Watanabe, Michael W Jenkins
BACKGROUND: The relationship between changes in endocardial cushion and resultant congenital heart diseases (CHD) has yet to be established. It has been shown that increased regurgitant flow early in embryonic heart development leads to endocardial cushion defects, but it remains unclear how abnormal endocardial cushions during the looping stages might affect the fully septated heart. The goal of this study was to reproducibly alter blood flow in vivo and then quantify the resultant effects on morphology of endocardial cushions in the looping heart and on CHDs in the septated heart...
February 17, 2017: Congenital Heart Disease
https://www.readbyqxmd.com/read/28204298/does-functional-capacity-depend-on-the-size-of-the-shunt-a-prospective-cohort-study-of-adults-with-small-unrepaired-ventricular-septal-defects%C3%A2
#2
Marie Maagaard, Johan Heiberg, Benjamin Asschenfeldt, Steffen Ringgaard, Vibeke E Hjortdal
No abstract text is available yet for this article.
February 14, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28204192/ventricular-septal-defect-an-unusual-cause-of-paradoxical-low-gradient-aortic-stenosis
#3
Quentin de Hemptinne, Benjamin De Becker, Philippe Unger
No abstract text is available yet for this article.
February 14, 2017: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/28203542/robotic-trans-atrial-and-trans-mitral-ventricular-septal-resection
#4
REVIEW
W Randolph Chitwood
Localized ventricular septal hypertrophy, also known as idiopathic hypertrophic subaortic stenosis or idiopathic hypertrophic subaortic septal obstruction (IHSS), can create severe ventricular outflow obstruction. This often results in a high sub-aortic pressure gradient with potentially lethal symptoms. In 1960, Braunwald described the hemodynamic characteristics of IHSS, and thereafter, Morrow developed a trans-aortic approach to resect a large part of the ventricular septum, enlarging the outflow tract. The Morrow operation has remained the gold standard for surgically treating this pathology...
January 2017: Annals of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/28199556/outcomes-of-perventricular-off-pump-versus-conventional-closure-of-ventricular-septal-defects-a-prospective-randomized-study%C3%A2
#5
Alexey Voitov, Alexander Omelchenko, Yuriy Gorbatykh, Gregory Zaitsev, Alexey Arkhipov, Ilya Soynov, Alexander Bogachev-Prokophiev, Alexander Karaskov
No abstract text is available yet for this article.
February 10, 2017: European Journal of Cardio-thoracic Surgery
https://www.readbyqxmd.com/read/28185355/catheter-ablation-of-ventricular-tachycardia-in-patients-with-mitraclip-device-preliminary-findings
#6
Laurent M Haegeli, Giuseppe D'Angelo, Nicola Trevisi, Stefano Stella, Alexander Breitenstein, Firat Duru, Corinna Brunckhorst, Paolo Della Bella
INTRODUCTION: Patients with mitral regurgitation are increasingly treated by percutaneous implantation of a MitraClip device. We investigate the feasibility and safety of the transmitral catheter route for catheter ablation of VT (ventricular tachycardia) in these patients. METHODS: The mitral valve with the MitraClip in situ was crossed under transesophageal three-dimensional echocardiographic and fluoroscopic guidance using a steerable sheath for ablation of the left ventricle...
February 10, 2017: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/28178156/hyperthyroidism-with-dome-and-dart-t-wave-a-case-report-a-care-compliant-article
#7
Ping Lai, Jing-Ling Yuan, Jin-Hua Xue, Yue-Qun Qiu
RATIONALE: Dome-and-dart T waves (or bifid T waves) are a rare phenomenon in the surface electrocardiogram. These wave forms are mainly observed in patients with congenital heart disease such as atrial septal defect and ventricular septal defect. And hyperthyroidism who presented with an electrocardiogram that had dome-and-dart T waves in a precordial lead is never been reported. PATIENT CONCERNS: The patient presented with continuous tachycardia, palpitations, chest tightness, and headache for 4 days, and aggravated for 1 day...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28176513/serum-bnp-level-expression-of-child-patients-suffering-from-ventricular-septal-defects-of-chd-and-its-relation-with-cardiac-function-and-heart-failure
#8
Weidong Xu, Huixian Tao, Dan Hu, Guojian Wang
BACKGROUND: To explore BNP level expression of child patients suffering from ventricular septal defects of CHD and analyze the relationship between BNP and cardiac function and heart failure. METHODS: To select 92 cases of child patients with ventricular septal defects of CHD in this hospital from Oct. 2012 to Sep. 2014, which were divided into no HF group (n=30), mild HF group (n=31) and moderate and severe HF group (n=31) based on the scoring standard of NYU PHFI...
February 7, 2017: Minerva Pediatrica
https://www.readbyqxmd.com/read/28174406/-suspended-ventricular-septal-defect-closure-due-to-heparin-resistance-report-of-a-case
#9
Yasuyuki Toyoda, Takahiro Takemura, Kazuaki Shiratori, Yasutoshi Tsuda, Gentaku Hama, Hirokazu Niitsu, Yujiro Kawai, Hirozo Kinami, Takehito Yokoyama, Yoshiharu Okada
We present a case of heparin resistance whereby open heart surgery was discontinued. A 53-year-old woman who was diagnosed with ventricular septal defect and atrial septal defect was scheduled for intracardiac repair. However, after intravenous heparin (400 U kg-1) supplementation, the activated clotting time (ACT) increased only to seconds. The operation was discontinued because the addition of heparin( 200 U kg-1) did not show sufficient prolongation of ACT, fully indicative of heparin resistance. Additional antithrombin III concentrate was also ineffective...
February 2017: Kyobu Geka. the Japanese Journal of Thoracic Surgery
https://www.readbyqxmd.com/read/28164029/trends-in-pediatric-echocardiography-and-the-yield-for-congenital-heart-disease-in-a-major-cardiac-referral-hospital-in-cameroon
#10
Clovis Nkoke, Eric Balti, Alain Menanga, Anastase Dzudie, Alain Lekoubou, Samuel Kingue, Andre Pascal Kengne
BACKGROUND: Congenital heart disease (CHD) is a common condition in children in Sub-Saharan Africa (SSA), where it is associated with poor outcomes. Diagnosis of CHD in SSA depends essentially on echocardiography, which is available only in few urban referral centers. Our aim was to assess time changes in the pattern of referral for pediatric echocardiography and the subsequent diagnosis of structural CHD in a major SSA city. METHODS: All pediatric echocardiography performed between 2004 and 2013 at the echocardiography laboratory of the Yaounde General Hospital were reviewed...
January 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28164015/post-traumatic-ventricular-septal-defect-a-rare-indication-for-extracorporeal-membrane-oxygenation-as-a-bridge-to-transplant
#11
María Alejandra Restrepo-Córdoba, Francisco José Hernández-Pérez, Manuel Francisco Gómez-Bueno, Juan Manuel Escudier-Villa, Evaristo Castedo, Javier Segovia, Luis Antonio Alonso-Pulpón
A ventricular septal defect (VSD) is a rare complication of blunt chest trauma. This report presents the case of a 44-year-old man who developed a VSD as a result of high-energy closed chest trauma. We describe the initial surgical and medical management of the cardiac rupture. After failed repair surgery, extracorporeal membrane oxygenation (ECMO) was used as a bridge to heart transplantation. We discuss the successful use of ECMO to improve the prognosis results in this rare and complex entity.
February 2017: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/28163430/surgical-repair-of-tricuspid-valve-leaflet-tear-following-percutaneous-closure-of-perimembranous-ventricular-septal-defect-using-amplatzer-duct-occluder-i-report-of-two-cases
#12
Saatchi Mahesh Kuwelker, Devi Prasad Shetty, Bharat Dalvi
Tricuspid valve (TV) injury following transcatheter closure of perimembranous ventricular septal defect (PMVSD) with Amplatzer ductal occluder I (ADO I), requiring surgical repair, is rare. We report two cases of TV tear involving the anterior and septal leaflets following PMVSD closure using ADO I. In both the patients, the subvalvular apparatus remained unaffected. The patients presented with severe tricuspid regurgitation (TR) 6 weeks and 3 months following the device closure. They underwent surgical repair with patch augmentation of the TV leaflets...
January 2017: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/28163421/should-we-close-small-ventricular-septal-defects
#13
EDITORIAL
Sangeetha Viswanathan, R Krishna Kumar
No abstract text is available yet for this article.
January 2017: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/28162114/surgical-closure-of-multiple-large-apical-ventricular-septal-defects-how-we-do-it
#14
Carolina Perez-Negueruela, Joan Carretero, Javier Mayol, José M Caffarena
The management of apical ventricular septal defects continues to be challenging because of the difficulty in achieving a complete closure without a left apical ventriculotomy. In this study, we present our innovative technique of closing multiple and/or large muscular apical ventricular septal defects through a right atriotomy. We operated three patients with multiple apical muscular trabecular ventricular septal defects ("Swiss cheese") using a technique that involved exclusion of the right ventricular apex...
February 6, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28154913/right-ventricle-to-pulmonary-artery-shunt-in-pulmonary-atresia-with-a-ventricular-septal-defect-a-word-of-caution
#15
Kwang Ho Choi, Si Chan Sung, Hyungtae Kim, Hyoung Doo Lee, Gil Ho Ban, Geena Kim, Hoon Ko
The management of pulmonary atresia with a ventricular septal defect (PA/VSD) depends on the anatomy of the pulmonary artery or on the surgical strategy used at individual institutions. In our institution, we adopted a right ventricle-to-pulmonary artery (RV-PA) shunt in 2011 as a palliative procedure for PA/VSD to overcome the disadvantages of a Blalock-Taussig shunt. We evaluated the results of the RV-PA shunt as initial palliative surgery for PA/VSD. Thirteen patients with ductus-dependent PA/VSD from August 2011 to August 2015 were enrolled...
February 3, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28140654/genome-wide-methylation-analysis-identifies-novel-cpg-loci-for-perimembranous-ventricular-septal-defects-in-human
#16
Kim Pj Wijnands, Jun Chen, Liming Liang, Michael Mpj Verbiest, Xihong Lin, Willem A Helbing, Adriana C Gittenberger-de Groot, Peter J van der Spek, André G Uitterlinden, Régine Pm Steegers-Theunissen
AIM: Congenital heart diseases are the most common birth defects worldwide and leading cause of infant mortality. The perimembranous ventricular septal defect is most prevalent. Epigenetics may provide an underlying mechanism of the gene-environment interactions involved. MATERIALS & METHODS: We examined epigenome-wide DNA methylation using the Illumina HumanMethylation450 BeadChip in 84 case children and 196 control children. RESULTS: We identified differential methylation of a CpG locus (cg17001566) within the PRDM16 gene after Bonferroni correction (p = 9...
January 31, 2017: Epigenomics
https://www.readbyqxmd.com/read/28139013/aortopulmonary-window-morphology-diagnosis-and-long-term-results
#17
Sachin Talwar, Palkesh Agarwal, Shiv Kumar Choudhary, Shyam Sunder Kothari, Rajnish Juneja, Anita Saxena, Balram Airan
OBJECTIVE: Aortopulmonary window (APW) is a rare congenital heart defect. We reviewed our experience with this condition over the last two decades. METHODS: Between September 1993 and December 2013, 62 patients underwent surgery for APW. Depending on the associated lesions, they were divided into two groups: Simple (Group 1) or complex (Group 2). In the complex group, six patients had a ventricular septal defect, five patients had interrupted aortic arch, three patients had tetralogy of Fallot, two patients had double outlet right ventricle, and one patient had the right pulmonary artery arising from the ascending aorta...
January 30, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/28132534/intraoperative-diagnosis-of-a-quadricuspid-aortic-valve
#18
Hassan Tatari, Maziar Gholampour Dehaki, Gholamreza Omrani, Hafez Ghaheri, Alwaleed Al-Dairy, Hojjat Mortezaeian
Quadricuspid aortic valve is a rare anomaly, and most patients require surgery for aortic regurgitation in the 5th or 6th decades of life; only a few cases of aortic valve repair in childhood have been reported. A 3-year-old boy was scheduled for ventricular septal defect closure and aortic valve repair. Quadricuspid aortic valve was an incidental finding at operation; it was repaired by joining the left anterior and right anterior cusps. At the 9-month follow-up, the patient had no more than mild aortic regurgitation...
January 1, 2017: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/28127793/primary-mural-endocarditis-without-valvular-involvement
#19
Mai Tahara, Tomoo Nagai, Yoshiyuki Takase, Shunichi Takiguchi, Yoshiaki Tanaka, Takashi Kunihara, Junko Arakawa, Kazuhiro Nakaya, Akira Hamabe, Youdou Gatate, Takehiko Kujiraoka, Hirotsugu Tabata, Shuichi Katsushika
Primary mural endocarditis is an extremely rare infection in which nonvalvular endocardial involvement is seen without any cardiac structural abnormalities such as ventricular septal defects. The rapid and precise diagnosis of this disease remains challenging. We present 2 cases (67- and 47-year-old male patients) of pathologically confirmed primary mural endocarditis that could have been detected by initial transthoracic echocardiography in the emergency department. Transthoracic echocardiography and transesophageal echocardiography play critical roles in the early recognition and confirmation of primary mural endocarditis...
January 27, 2017: Journal of Ultrasound in Medicine: Official Journal of the American Institute of Ultrasound in Medicine
https://www.readbyqxmd.com/read/28116756/branch-pulmonary-artery-peel-operation-in-a-patient-without-a-native-intrapericardial-pulmonary-artery
#20
Hyungtae Kim, Si Chan Sung, Kwang Ho Choi, Hyoung Doo Lee, Gil Ho Ban, Geena Kim, Hee Young Kim
A patient with pulmonary atresia with ventricular septal defect and major aortopulmonary collateral arteries without an intrapericardial pulmonary artery (PA) underwent a one-stage total correction, including both branch PA reconstructions, with a bovine pericardial roll at the age of 42 months. She was readmitted 54 months after the operation because of extracardiac conduit bacterial endocarditis and pulmonary infarction. The bovine pericardial roll between the right and left PAs was enucleated, and the surrounding fibrotic tissue (peel) was used as a new branch PA vascular conduit...
January 23, 2017: Journal of Cardiac Surgery
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