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https://www.readbyqxmd.com/read/28109092/-early-outcomes-of-elective-surgery-for-colon-cancer-with-preoperative-mechanical-bowel-preparation-a-randomized-clinical-trial
#1
Yan-Jie Hu, Ka Li, Li Li, Xiao-Dong Wang, Jie Yang, Jin-Hua Feng, Wei Zhang, Yu-Wei Liu
OBJECTIVE: To compared the early outcomes of patients undergoing elective surgeries for colon cancer with and without preoperative mechanical bowel preparation. METHODS: Between July, 2014 and February, 2016, patients undergoing elective surgery for colon cancer with primary anastomosis were randomly assigned into control group with mechanical bowel preparation 12 h before surgery and treatment group without mechanical bowel preparation. Baseline data collection was completed within 12 h after the operation...
January 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28074767/-diet-consisting-mainly-of-sunflower-seeds-and-chicken-as-the-cause-of-small-bowel-obstruction-in-a-bodybuilder
#2
Tine Thorup, Rasmus Fabricius
Diet-induced small bowel obstruction is a rare condition in young, healthy patients. We describe a case of a 26-year-old man, who presented with acute small bowel obstruction. During a period of eight days prior to admission the patient had been eating an extremely restricted diet along with a regulated intake of fluids. The diet was part of a preparation for a major fitness contest. We chose a conservative treatment of IV fluids and laxatives, and the patient recovered uneventfully.
January 9, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28070476/evaluating-screening-colonoscopy-quality-in-an-uninsured-urban-population-following-patient-navigation
#3
Keith Naylor, Cassandra Fritz, Blase Polite, Karen Kim
Patient navigation (PN) increases screening colonoscopy completion in minority and uninsured populations. However, colonoscopy quality is under-reported in the setting of PN and quality indicators have often failed to meet benchmark standards. This study investigated screening colonoscopy quality indicators after year-one of a PN initiative targeting the medically uninsured. This was a retrospective analysis of 296 outpatient screening colonoscopies. Patients were 45 to 75 years of age with no history of bowel cancer, inflammatory bowel disease, or colorectal surgery...
March 2017: Preventive Medicine Reports
https://www.readbyqxmd.com/read/28069880/repair-of-a-bowel-containing-scrotal-hernia-with-incarceration-contributed-by-femorofemoral-bypass-graft
#4
Gaurav Sharma, Jonathan A Schouten, Kamal M F Itani
The rising use of endovascular techniques utilizing femoral artery access may increase the frequency with which surgeons face the challenge of hernia repair in reoperative groins-which may or may not include a vascular graft. We present a case where a vascular graft contributed to an acute presentation and complicated dissection, and review the literature. A 67-year-old man who had undergone prior endovascular aneurysm repair via open bilateral femoral artery access and concomitant prosthetic femorofemoral bypass, presented with an incarcerated, scrotal inguinal hernia...
January 8, 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28068788/a-double-blind-randomized-placebo-controlled-trial-of-lactobacillus-helveticus-and-bifidobacterium-longum-for-the-symptoms-of-depression
#5
Amy R Romijn, Julia J Rucklidge, Roeline G Kuijer, Chris Frampton
OBJECTIVES: This trial investigated whether probiotics improved mood, stress and anxiety in a sample selected for low mood. We also tested whether the presence or severity of irritable bowel syndrome symptoms, and levels of proinflammatory cytokines, brain-derived neurotrophic factor and other blood markers, would predict or impact treatment response. METHOD: Seventy-nine participants (10 dropouts) not currently taking psychotropic medications with at least moderate scores on self-report mood measures were randomly allocated to receive either a probiotic preparation (containing Lactobacillus helveticus and Bifidobacterium longum) or a matched placebo, in a double-blind trial for 8 weeks...
January 1, 2017: Australian and New Zealand Journal of Psychiatry
https://www.readbyqxmd.com/read/28067463/enhanced-education-for-bowel-preparation-before-colonoscopy-a-state-of-the-art-review
#6
Zhu Liu, Ming Ming Zhang, Yue Yue Li, Li Xiang Li, Yan Qing Li
Colonoscopy remains the mainstay in the diagnosis and monitoring for colorectal cancer and other colorectal lesions. The diagnostic efficiency of colonoscopy highly depends on the quality of bowel preparation, which is closely associated with patient's compliance to preparation instructions. In addition, the procedural requirements of bowel preparation are often complex and difficult to be comprehended and memorized by patients, especially those with lower health literacy and motivation. Therefore, in recent years, many educational methods have been constantly developed, such as educational booklets, cartoon visual aids, educational videos, the short message service, the telephone, social media applications and smart phone applications...
January 9, 2017: Journal of Digestive Diseases
https://www.readbyqxmd.com/read/28062864/-comparison-of-colon-cleansing-methods-in-preparation-for-colonoscopy-comparative-of-solutions-of-mannitol-and-sodium-picosulfate
#7
Diogo Turiani de Moura, Hugo Guedes, Verônica Tortoretto, Tayrê Pádua Arataque, Eduardo Guimarães de Moura, Juan Pablo Román, Gustavo Luis Rodela, Everson L Artifon
OBJECTIVES: The purpose of the present study is to compare intestinal preparation with mannitol and sodium picosulphate, assessing patient's acceptance, side effects and cleaning capacity. MATERIAL AND METHODS: This is a prospective, nom randomized, blind study, in which the evaluator had no information about the preparation applied. The sample obtained was divided into two groups according to the bowel preparation applied, with 153 patients prepared with 10% mannitol and 84 patients with sodium picosulfate...
October 2016: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
https://www.readbyqxmd.com/read/28057560/predictors-of-failure-after-single-faecal-microbiota-transplantation-in-patients-with-recurrent-clostridium-difficile-infection-results-from-a-three-year-single-centre-cohort-study
#8
Gianluca Ianiro, Luca Valerio, Luca Masucci, Silvia Pecere, Stefano Bibbò, Gianluca Quaranta, Brunella Posteraro, Diego Currò, Maurizio Sanguinetti, Antonio Gasbarrini, Giovanni Cammarota
OBJECTIVES: Faecal microbiota transplantation (FMT) is an effective treatment for recurrent Clostridium difficile infection (CDI). Although a single faecal infusion is usually sufficient to eradicate CDI, a considerable rate of patients needs multiple infusions to be cured. The aim of this study was to identify predictors of failure after single faecal infusion in patients with recurrent CDI. METHODS: We included patients with recurrent CDI prospectively treated with FMT by colonoscopy...
January 2, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28057275/anatomic-suitability-for-transcaval-access%C3%A2-based-on-computed-tomography
#9
REVIEW
Robert J Lederman, Adam B Greenbaum, Toby Rogers, Jaffar M Khan, Melissa Fusari, Marcus Y Chen
Transcaval access has been used successfully for over 200 transcatheter aortic valve replacements, large-bore percutaneous left ventricular assist devices, and thoracic endovascular aortic aneurysm repairs. This review teaches how to plan transcaval access and closure based on computed tomography. The main planning goals are to: 1) identify calcium-free crossing targets in the abdominal aorta along with optimal fluoroscopic projection angles and level with respect to lumbar vertebrae; 2) identify obstacles such as interposed bowel or pedunculated aortic atheroma; 3) plan covered stent bailout; and 4) identify jeopardized vascular branches such as renal arteries that might be obstructed by bailout covered stents if employed...
January 9, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28056732/development-of-a-radiolabeled-amlodipine-analog-for-l-type-calcium-channel-imaging
#10
Tahereh Firouzyar, Amir Reza Jalilian, Mohammad Reza Aboudzadeh, Hossein Sadeghpour, Mehrban Pooladi, Mahdi Shafiee-Ardestani, Ali Khalaj
PURPOSE: The non-invasive imaging and quantification of L-type calcium channels in living tissues is of great interest in diagnosis of congestive heart failure, myocardial hypertrophy, irritable bowel syndrome etc. METHODS: Technetium-<sup>99m</sup> labeled amlodipine conjugate ([<sup>99m</sup>Tc]-DTPA-AMLO) was prepared starting freshly eluted (<1 h) <sup>99m</sup>Technetium pertechnetate (86.5 MBq) and conjugated DTPA-AMLO at pH 5 in 30 min at room temperature in high radiochemical purity (>99%, RTLC; specific activity: 55-60 GBq/mmol)...
January 4, 2017: Current Radiopharmaceuticals
https://www.readbyqxmd.com/read/28055031/a-customized-mobile-application-in-colonoscopy-preparation-a-randomized-controlled-trial
#11
Ala I Sharara, Jean M Chalhoub, Maya Beydoun, Rani H Shayto, Hamed Chehab, Ali H Harb, Fadi H Mourad, Fayez S Sarkis
OBJECTIVES: Adherence with diet and prescribed purgative is essential for proper cleansing with low-volume bowel preparations. The aim of this work was to assess the effect of a customized mobile application (App) on adherence and quality of bowel preparation. METHODS: One hundred and sixty (160) eligible patients scheduled for elective colonoscopy were randomly assigned to paper (control) or App-based instructions. The preparation consisted of low-fiber diet for 2 days, clear fluids for one day and split-dose sodium picosulfate/magnesium citrate (SPS)...
January 5, 2017: Clinical and Translational Gastroenterology
https://www.readbyqxmd.com/read/28049271/dietary-intake-physical-activity-and-time-management-are-associated-with-constipation-in-preschool-children-in-japan
#12
Keiko Asakura, Shizuko Masayasu, Satoshi Sasaki
BACKGROUND AND OBJECTIVES: Constipation is a common complaint in children, which is not fatal but can affect quality of life. Several lifestyle-related risk factors for constipation have been reported, particularly dietary factors, but results have been inconsistent. Here, we examined the relationship of dietary and lifestyle factors with constipation in Japanese preschool children using data of a nationwide study. METHODS AND STUDY DESIGN: Subjects were 5,309 children aged 5 to 6 years at 380 nursery schools in 44 of 47 prefectures in Japan...
January 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28047014/su-d-201-02-a-systematic-planning-quality-monitoring-program-for-vmat-treatment
#13
G Zeng, M Robertson, J Murphy, M Lamey, Y Wang
PURPOSE: To demonstrate a systematic tracking program for planning quality; to advocate that commercial treatment planning systems develop tools to monitor population-based quality in order to justify technology change in respect to clinical outcome. METHODS: The DVH (Dose Volume Histogram) files of VMAT patients since 2011 have been exported from Varian Eclipse treatment planning system. The nomenclature of structures has been standardized and the planning process has been semi-automated for clinical sites where such efforts bring clinical and operational benefits, such as GU...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28042393/current-state-of-practice-for-colonic-diverticular-bleeding-in-37-hospitals-in-japan-a-multicenter-questionnaire-study
#14
Ryota Niikura, Naoyoshi Nagata, Hisashi Doyama, Ryosuke Ota, Naoki Ishii, Katsuhiro Mabe, Tsutomu Nishida, Takuto Hikichi, Kazuki Sumiyama, Jun Nishikawa, Toshio Uraoka, Shu Kiyotoki, Mitsuhiro Fujishiro, Kazuhiko Koike
AIM: To clarify the current state of practice for colonic diverticular bleeding (CDB) in Japan. METHODS: We conducted multicenter questionnaire surveys of the practice for CDB including clinical settings (8 questions), diagnoses (8 questions), treatments (7 questions), and outcomes (4 questions) in 37 hospitals across Japan. The answers were compared between hospitals with high and low number of inpatient beds to investigate which factor influenced the answers. RESULTS: Endoscopists at all 37 hospitals answered the questions, and the mean number of endoscopists at these hospitals was 12...
December 16, 2016: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28042391/identification-of-factors-associated-with-sedation-tolerance-in-5000-patients-undergoing-outpatient-colonoscopy-canadian-tertiary-center-experience
#15
Alexandra Shingina, George Ou, Oliver Takach, Sigrid Svarta, Ricky Kwok, Jessica Tong, Kieran Donaldson, Eric Lam, Robert Enns
AIM: To develop a prediction model aimed at identifying patients that may require higher than usual sedation doses during colonoscopy. METHODS: A retrospective chart review on 5000 patients who underwent an outpatient colonoscopy at St. Paul's Hospital from 2009 to 2010 was conducted in order to develop a model for identifying patients who will require increased doses of sedatives. Potential predictor variables including age, gender, endoscopy indication, high sedation requirements during previous endoscopies, difficulty of the procedure, bowel preparation quality, interventions, findings as well as current use of benzodiazepines, opioids and alcohol were analyzed...
December 16, 2016: World Journal of Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28042237/gut-microbiome-surgical-complications-and-probiotics
#16
REVIEW
George Stavrou, Katerina Kotzampassi
The trigger for infectious complications in patients following major abdominal operations is classically attributed to endogenous enteral bacterial translocation, due to the critical condition of the gut. Today, extensive gut microbiome analysis has enabled us to understand that almost all "evidence-based" surgical or medical intervention (antibiotics, bowel preparation, opioids, deprivation of nutrition), in addition to stress-released hormones, could affect the relative abundance and diversity of the enteral microbiome, allowing harmful bacteria to proliferate in the place of depressed beneficial species...
2017: Annals of Gastroenterology: Quarterly Publication of the Hellenic Society of Gastroenterology
https://www.readbyqxmd.com/read/28040561/development-and-characterization-of-anti-inflammatory-activity-of-curcumin-loaded-biodegradable-microspheres-with-potential-use-in-intestinal-inflammatory-disorders
#17
E Blanco-García, F J Otero-Espinar, J Blanco-Méndez, J M Leiro-Vidal, A Luzardo-Álvarez
This research addresses the development and in vitro evaluation of a microparticulate system intended for intestine-targeted delivery of curcumin (CRM), a natural polyphenol with anti-inflammatory properties. Microspheres (Ms) based on zein (ZN) and Gantrez(®) AN119 (PVMMA) were prepared by spray-drying and coated with a pH-sensitive polymer (Eudragit(®) FS30D). An experimental design was performed to optimize the microparticulate formulation. A detailed characterization of systems was carried out by SEM, DSC, FTIR, particle size, ζ potential measurements and in vitro CRM release...
December 28, 2016: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28035547/diabetics-on-narcotics-are-less-likely-to-achieve-excellent-bowel-preparation-than-are-patients-with-either-condition
#18
Mohammad F Madhoun, Hussein Bitar, Owais Bhatti, Hassaan Zia, Pratyusha Parava, Muhammad H Bashir
BACKGROUND: Diabetes and chronic narcotic use negatively affect the quality of bowel preparation before colonoscopy. AIM: To investigate whether narcotic use and diabetes have an additive negative impact on bowel preparation. PATIENTS AND METHODS: We performed a retrospective study of 2841 patients (mean age 61 ± 10.2; 94% male) who received outpatient colonoscopies at our Veterans Affairs Medical Center between June 2012 and December 2014...
December 29, 2016: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28034350/rifaximin-chitosan-nanoparticles-for-inflammatory-bowel-disease-ibd
#19
Maria John Newton, Jatinder Kumar
BACKGROUND: Inflammatory Bowel Disease ( IBD) can't be controlled easily and the recurrence is most challenging issue for the physicians. There are various controlled and colon targeted drug delivery sytems are available for the treatment with limited success rate. Nanoparticles prepared by using the colon targeted polymers such as chitosan may improve the IBD due to their smaler size, unique physico chemical properties and targeting potential. OBJECTIVE: The aim of this investigation was designed to formulate and develop a colon targeted polysaccharide nanoparticles of Rifaximin (RFX) by using linear polysaccharide chitosan, for the improvement of rifaximin solubility, overall therapeutic efficacy and colon targeting...
December 30, 2016: Recent Patents on Inflammation & Allergy Drug Discovery
https://www.readbyqxmd.com/read/28028560/pathophysiology-prevention-treatment-and-outcomes-of-intestinal-failure-associated-liver-disease
#20
REVIEW
Noora H Al-Shahwani, David L Sigalet
BACKGROUND: Intestinal failure-associated liver disease (IFALD) remains a serious problem in the treatment of infants with nutritional problems and short bowel syndrome. METHODS: A review of the recent literature from 2010 to 2016, concentrating on articles related to the pathophysiology of IFALD and to outcomes of novel nutritional and pharmacological therapies for neonatal cholestasis in the post-surgical neonate. RESULTS: The pathophysiology of IFALD relates to an increase sensitivity of the neonatal liver to cholestasis in the non-fed state; prolonged cholestasis almost inevitably results in liver damage which will progress from fibrosis to cirrhosis...
December 27, 2016: Pediatric Surgery International
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