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Periodontal therapy

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https://www.readbyqxmd.com/read/28208029/l1-peptide-conjugated-fibrin-hydrogels-promote-salivary-gland-regeneration
#1
K Nam, C-S Wang, C L M Maruyama, P Lei, S T Andreadis, O J Baker
Hyposalivation contributes to dental caries, periodontitis, and microbial infections. Additionally, it impairs activities of daily living (e.g., speaking, chewing, and swallowing). Treatments for hyposalivation are currently limited to medications (e.g., the muscarinic receptor agonists pilocarpine and cevimeline) that induce saliva secretion from residual acinar cells and the use of saliva substitutes. However, given that these therapies provide only temporary relief, the development of alternative treatments to restore gland function is essential...
February 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28204842/the-effect-of-nonsurgical-periodontal-therapy-on-hnp1-3-level-in-gingival-crevicular-fluid-of-chronic-periodontitis-patients
#2
Ewa Dolińska, Anna Skurska, Małgorzata Pietruska, Violetta Dymicka-Piekarska, Robert Milewski, Jan Pietruski, Anton Sculean
The rich bacterial flora of oral cavity is controlled by innate immune response, including antibacterial peptides and among them human neutrophil peptides 1-3 (HNP1-3). The knowledge of the involvement of HNPs in innate and acquired immunity of the periodontium is fragmentary. The aim of the study was to assess alterations in HNP1-3 levels in the gingival crevicular fluid (GCF) of chronic periodontitis patients before and after nonsurgical periodontal therapy. Nineteen patients with chronic periodontitis were qualified to the study...
February 15, 2017: Archivum Immunologiae et Therapiae Experimentalis
https://www.readbyqxmd.com/read/28204808/bone-morphogenetic-protein-2-enhances-the-osteogenic-differentiation-capacity-of-mesenchymal-stromal-cells-derived-from-human-bone-marrow-and-umbilical-cord
#3
Kulisara Marupanthorn, Chairat Tantrawatpan, Pakpoom Kheolamai, Duangrat Tantikanlayaporn, Sirikul Manochantr
Mesenchymal stromal cells (MSCs) are multipotent cells that can give rise to different cell types of the mesodermal lineages. They are powerful sources for cell therapy in regenerative medicine as they can be isolated from various tissues, and can be expanded and induced to differentiate into multiple lineages. Recently, the umbilical cord has been suggested as an alternative source of MSCs. Although MSCs derived from the umbilical cord can be induced to differentiate into osteoblasts with a phenotypic similarity to that of bone marrow-derived MSCs, the differentiation ability is not consistent...
February 1, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28203003/-bleeding-control-of-periodontal-mechanical-therapy-for-patients-taking-aspirin
#4
F Ding, Y L Lyu, W Xuan, D Y Liu, X Q Duan, X Han
OBJECTIVE: To investigate the feasibility of periodontal mechanical therapy for chronic periodontitis and coronary heart disease patients with low dose of aspirin. METHODS: Sixty nine chronic periodontitis patients with coronary heart disease were randomly selected as the experimental group (medication group, group A), the control group (withdrawal group, group B) including 20 chronic periodontitis patients with coronary artery disease, stopping the drug for one week and another control group with 50 chronic periodontitis patients (group C)...
February 18, 2017: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/28196168/treatment-concept-for-a-patient-with-a-high-smile-line-and-gingival-pigmentation-a-case-report
#5
Fernando Zarone, Renato Leone, Marco Ferrari, Roberto Sorrentino
Today, innovative restorative materials and techniques allow for minimally invasive prosthetic procedures, which are paramount to the preservation of hard and soft dental tissues. An integrated approach combining dental and esthetic medical therapies could be useful to improve the quality of life of patients, improving function, esthetics, and self-confidence. Oral esthetics depends on several variables, including tooth visibility and proportions as well as healthy gingival tissues. Proper integration between teeth and periodontal tissues plays an important role in esthetic success, which is mainly represented by an appealing smile...
March 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28196153/periodontal-regenerative-therapy-of-intrabony-defects-using-deproteinized-bovine-bone-mineral-in-combination-with-collagen-barrier-membrane-a-multicenter-prospective-case-series-study
#6
Daisuke Irokawa, Nobuki Okubo, Masahiko Nikaido, Hiroyasu Shimizu, Nobuyuki Konobu, Tokuo Matsui, Takahisa Fujita, Hiroaki Goto, Takahiro Takeuchi, Yoshihito Ishii, Atsushi Saito
This multicenter prospective case series study aimed to evaluate the outcome of periodontal regenerative therapy using a deproteinized bovine bone mineral (DBBM) in combination with a collagen barrier (CB) in the treatment of intrabony defects. A total of 36 nonsmoking patients with chronic periodontitis were recruited in five centers in Japan. All patients had at least one intrabony defect of ≥ 3 mm. The surgical procedures included access for debridement using a papilla preservation technique. Defects were filled with DBBM and covered with CB...
February 14, 2017: International Journal of Periodontics & Restorative Dentistry
https://www.readbyqxmd.com/read/28195408/microrna-22-promoted-osteogenic-differentiation-of-human-periodontal-ligament-stem-cells-by-targeting-hdac6
#7
Guang-Qi Yan, Xue Wang, Fan Yang, Min-Liang Yang, Guo-Kun Wang, Qing Zhou
Stem cells transplantation is a promising therapy strategy for accelerating periodontal regeneration and reconstruction. Genetic modification could induce stem cells directional differentiation to facilitate recovery of physiological functions. In this study, we investigated the role and mechanism of miR-22 on human periodontal ligament stem cells (PDLSCs). Firstly, a cellular model of osteogenic differentiation was first established by osteogenic inductive cocktail. Real-time PCR determined that expression of miR-22 was significantly increased during PDLSCs osteogenic differentiation...
February 13, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28194367/retreatment-of-failed-regenerative-endodontic-of-orthodontically-treated-immature-permanent-maxillary-central-incisor-a-case-report
#8
Musaed Fahad Al-Tammami, Saad A Al-Nazhan
A revascularization procedure was shown to be the best alternative therapy for immature teeth with necrotic pulp and apical infection. A 12 year old female with a history of trauma to her upper central incisor and a sinus tract was referred for endodontic treatment. She was an active orthodontic patient and had undergone regenerative endodontic treatment for the past 2 years. Clinical examination revealed no response to sensibility, percussion, and palpation tests. The preoperative radiograph showed an open apex and apical rarefaction...
February 2017: Restorative Dentistry & Endodontics
https://www.readbyqxmd.com/read/28190975/reduced-platelet-hyper-reactivity-and-platelet-leukocyte-aggregation-after-periodontal-therapy
#9
Efthymios Arvanitidis, Sergio Bizzarro, Elena Alvarez Rodriguez, Bruno G Loos, Elena A Nicu
BACKGROUND: Platelets from untreated periodontitis patients are hyper-reactive and form more platelet-leukocyte complexes compared to cells from individuals without periodontitis. It is not known whether the improvement of the periodontal condition achievable by therapy has beneficial effects on the platelet function. We aimed to assess the effects of periodontal therapy on platelet reactivity. METHODS: Patients with periodontitis (n = 25) but unaffected by any other medical condition or medication were included and donated blood before and after periodontal therapy...
2017: Thrombosis Journal
https://www.readbyqxmd.com/read/28188919/clinical-efficacy-of-photodynamic-therapy-adjunctive-to-scaling-and-root-planing-in-the-treatment-of-chronic-periodontitis-a-systematic-review-and-meta-analysis
#10
Dong Xue, Lu Tang, Yuhao Bai, Qian Ding, Pengcheng Wang, Ying Zhao
PURPOSE: To evaluate the clinical efficacy of photodynamic therapy (PDT) adjunctive to scaling and root planing (SRP) in patients with untreated chronic periodontitis based on the up-to-date evidence. METHODS: MEDLINE and the Cochrane Library were systematically searched to identify eligible random controlled trials (RCTs), supplemented by a manual literature search. Mean differences (MD) and the corresponding 95% confidence intervals (CI) of probing depth (PD) reduction and clinical attachment level (CAL) gain were synthesized...
February 7, 2017: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/28186646/re-evaluation-of-the-adjunctive-effect-of-platelet-rich-fibrin-to-enamel-matrix-derivative-in-the-treatment-of-intrabony-defects-six-month-results-of-a-randomized-split-mouth-controlled-clinical-study
#11
Eralp Buduneli, Nurcan Buduneli
We have read with great interest the recent article by Turkal et al. (2016). In their study, the results obtained with enamel matrix derivative (EMD) and EMD + platelet-rich fibrin (PRF) were compared in the treatment of intrabony defects in patients with chronic periodontitis. The authors concluded that both therapies resulted in significant clinical improvement in intrabony defect treatment, but addition of PRF did not improve the clinical and radiographic outcomes. A recent review article provided the biological background for the use of EMD and discussed the current evidence for periodontal regeneration (Miron et al...
February 10, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28183218/videoscope-assisted-minimally-invasive-periodontal-surgery-vmis-long-term-outcomes
#12
Stephen K Harrel, Martha E Nunn, Celeste M Abraham, Francisco Rivera-Hidalgo, Jay D Shulman, John C Tunnell
BACKGROUND: The 36 to 58 month clinical outcomes from videoscope assisted minimally invasive surgery (VMIS) are reported. METHODS: Fourteen patients having sites with residual pocket probing depth (PPD) of at least 5 mm and 2 mm of clinical attachment level (CAL) loss following initial nonsurgical therapy were treated with VMIS. RESULTS: At 36 months or greater post surgery there was a statistically significant improvement (p <0.001) in mean PPD and CAL (PPD 3...
February 9, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28181911/molecular-diagnostics-of-periodontitis
#13
Izabela Korona-Głowniak, Radosław Siwiec, Marcin Berger, Anna Malm, Jolanta Szymańska
The microorganisms that form dental plaque are the main cause of periodontitis. Their identification and the understanding of the complex relationships and interactions that involve these microorganisms, environmental factors and the host's health status enable improvement in diagnostics and targeted therapy in patients with periodontitis. To this end, molecular diagnostics techniques (both techniques based on the polymerase chain reaction and those involving nucleic acid analysis via hybridization) come increasingly into use...
January 28, 2017: Postȩpy Higieny i Medycyny Doświadczalnej
https://www.readbyqxmd.com/read/28181073/erratum-to-outcomes-of-implant-therapy-in-patients-with-a-history-of-aggressive-periodontitis-a-systematic-review-and-meta-analysis
#14
Charis Theodoridis, Andreas Grigoriadis, Georgios Menexes, Ioannis Vouros
No abstract text is available yet for this article.
February 9, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28179939/autogenous-transplantation-for-replacing-a-hopeless-tooth
#15
Mehrsa Zakershahrak, Amirabbas Moshari, Mehdi Vatanpour, Zohreh Khalilak, Afsoon Jalali Ara
Autogenous tooth transplantation (ATT) is a simple and reasonable choice for replacing the missing teeth when a proper donor tooth is available. This report presents a case of successful ATT of a maxillary right third molar for replacement of mandibular right second molar with a concomitant endodontic-periodontal disease. The mandibular second molar was believed to be hopeless due to a severe damage to coronal tooth structure, inappropriate root canal treatment and apical radiolucency. After extraction of mandibular second molar and maxillary third molar (the donor), the tooth was re-implanted into the extracted socket of second molar site...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28177133/dietary-supplementation-with-low-dose-omega-3-fatty-acids-reduces-salivary-tumor-necrosis-factor-%C3%AE-levels-in-patients-with-chronic-periodontitis-a-randomized-controlled-clinical-study
#16
I Keskiner, I Saygun, V Bal, M Serdar, A Kantarci
BACKGROUND AND OBJECTIVE: Recent studies have demonstrated the beneficial effects of omega-3 polyunsaturated fatty acids (PUFAs) on physiological processes and on a variety of chronic inflammatory diseases, including periodontal diseases. In this study, we evaluated the impact of omega-3 PUFAs in conjunction with scaling and root planing (SRP) on salivary markers in patients with chronic periodontitis. MATERIAL AND METHODS: Thirty systemically healthy subjects with chronic periodontitis were enrolled and randomly allocated into two groups...
February 8, 2017: Journal of Periodontal Research
https://www.readbyqxmd.com/read/28174364/evaluation-of-periodontal-changes-adjacent-to-extraction-sites-during-upper-canine-retraction
#17
Azzam Al-Jundi, Basem Al Sabbagh, Jagan K Baskaradoss
INTRODUCTION: There is an intimate relationship between orthodontic therapy and the periodontal changes that occur during tooth movement. MATERIALS AND METHODS: This prospective clinical trial aims at investigating the movement of both the free and attached gingiva, as well as the movement of the alveolar bone in the extraction site of the upper 1st premolars during the retraction of the upper canines. In this study, 17 patients (10 female, 7 male) requiring 1st premolar extraction before orthodontic tooth movement were selected and treated at the Department of Orthodontics in the Faculty of Dentistry in University of Hama, Hama, Syria...
February 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28171221/the-significance-of-electron-microscopic-examination-of-gingiva-in-cases-of-hunter-syndrome-and-hereditary-gingival-fibromatosis
#18
(no author information available yet)
INTRODUCTION: Electron microscopy has been for decades a basic morphological method still used in diagnostic protocols of some pathological conditions affecting the ultrastructure of cells and extracellular matrix. The aim of this study was an ultrastructural description of gingiva of patients with Hunter syndrome and hereditary gingival fibromatosis. PATIENTS AND METHODS: Gingival biopsies were obtained during surgical periodontal treatment from a 9-year-old boy with Hunter disease (with enzyme replacement therapy with recombinant human idursulphase) and a 15-year-old girl with hereditary gingival fibromatosis...
October 8, 2016: Neuro Endocrinology Letters
https://www.readbyqxmd.com/read/28169258/the-effect-of-indocyanine-green-mediated-photodynamic-therapy-as-an-adjunct-to-scaling-and-root-planing-in-the-treatment-of-chronic-periodontitis-a-comparative-split-mouth-randomized-clinical-trial
#19
Saurabh H Shingnapurkar, Dipika K Mitra, Mitali Suresh Kadav, Rohit A Shah, Silvia V Rodrigues, Saurabh S Prithyani
OBJECTIVE: The aim of this study was to assess the effect of adjunctive photodynamic therapy (PDT) (using 810 nm diode laser and Indocyanine green as photosensitizer) in chronic periodontitis. MATERIALS AND METHODS: Patients with untreated chronic periodontitis were included. Treatment was done according to a split mouth design. All sites received periodontal treatment comprising scaling and root-planing (SRP). Test group were additionally treated with PDT. Plaque Index (PI), Gingival Index (GI), Probing Pocket Depth (PPD) and Relative Attachment Level (RAL) were evaluated at baseline, 1 month and 3 months...
November 2016: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/28168362/practical-methods-for-handling-human-periodontal-ligament-stem-cells-in-serum-free-and-serum-containing-culture-conditions-under-hypoxia-implications-for-regenerative-medicine
#20
Dai Murabayashi, Mai Mochizuki, Yuichi Tamaki, Taka Nakahara
Stem cell-based therapies depend on the reliable expansion of patient-derived mesenchymal stem cells (MSCs) in vitro. The supplementation of cell culture media with serum is associated with several risks; accordingly, serum-free media are commercially available for cell culture. Furthermore, hypoxia is known to accelerate the expansion of MSCs. The present study aimed to characterize the properties of periodontal ligament-derived MSCs (PDLSCs) cultivated in serum-free and serum-containing media, under hypoxic and normoxic conditions...
February 6, 2017: Human Cell
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