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Periodontal therapy

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https://www.readbyqxmd.com/read/29044527/effect-of-the-combined-use-of-enamel-matrix-derivative-and-atelocollagen-sponge-scaffold-on-osteoblastic-differentiation-of-mouse-induced-pluripotent-stem-cells-in-vitro
#1
Y Hisanaga, E Suzuki, H Aoki, M Sato, A Saito, A Saito, T Azuma
BACKGROUND AND OBJECTIVE: Induced pluripotent stem cells (iPSCs) are a candidate cell source in periodontal regenerative therapy. Enamel matrix derivative (EMD) has been shown to regenerate periodontal tissues, and atelocollagen sponge (ACS) is considered a suitable scaffold or carrier for growth factors. This study aimed to investigate the effect of combined use of EMD and an ACS scaffold on cell behaviors and differentiation of mouse iPSCs (miPSCs) in vitro. MATERIAL AND METHODS: Following embryonic body formation from miPSCs, dissociated cells (miPS-EB-derived cells) were seeded onto ACS with or without EMD, and cultured in osteoblast differentiation medium...
October 17, 2017: Journal of Periodontal Research
https://www.readbyqxmd.com/read/29042721/clinical-and-radiographic-evaluation-of-citric-acid-based-nano-hydroxyapatite-composite-graft-in-the-regeneration-of-intrabony-defects-a-randomized-controlled-trial
#2
Chaurasia Priya Dayashankar, P C Deepika, Basavarajaiah Siddaramaiah
BACKGROUND: Conventional periodontal therapy with various bone grafts has limited scope and the results are not predictable. To improve their utility, the hybridization of bioceramics and biodegradable polymers has been widely adopted to reform the mechanical properties of bone grafts. One such biodegradable polymer is POC (Poly 1,8 octanediol). Secondly, citric acid is considered as the key material in bone mineralization, which is related to the overall stability, strength and fracture resistance of bone...
July 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/29034501/influence-of-dental-materials-on-cells-of-the-equine-periodontium
#3
H Ringeisen, A Pöschke, B Krähling, C Schröck, M Stoll, J Vogelsberg, K Failing, C Staszyk
BACKGROUND: Therapy for equine periodontal disease can include filling of the periodontal pockets and widened interproximal spaces. Recommended dental materials are generally adopted from human dentistry. OBJECTIVES: To evaluate the biocompatibility of dental materials for equine periodontal fillings in vitro. STUDY DESIGN: In vitro experiments. METHODS: Four different dental materials (PeriCare(®) , Provicol(®) , Calxyl(®) and Honigum) were tested on equine periodontal fibroblasts...
October 16, 2017: Equine Veterinary Journal
https://www.readbyqxmd.com/read/29033088/evaluation-of-effect-of-foraminal-enlargement-of-necrotic-teeth-on-postoperative-symptoms-a-systematic-review-and-meta-analysis
#4
REVIEW
Erlange Andrade Borges Silva, Ludmila Silva Guimarães, Erika Calvano Küchler, Lívia Azeredo A Antunes, Leonardo Santos Antunes
INTRODUCTION: The intentional enlargement of the apical foramen is designed to reduce the microbial load in the apical foramen, or even beyond, to levels more favorable for repair. This study provides a systematic review and meta-analysis to address the PICOS question: in adult patients who undergo endodontic treatment, does foraminal enlargement (FE) cause different postoperative symptoms in comparison with conventional endodontic treatment? METHODS: The PROSPERO registration number is CRD42017059921 and was conducted following the PRISMA statements...
October 12, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/29031949/evaluation-of-irimedadi-taila-as-an-adjunctive-in-treating-plaque-induced-gingivitis
#5
Shweta Patil, Siddhartha A Varma, Girish Suragimath, Keshava Abbayya, Sameer A Zope, Vishwajeet Kale
BACKGROUND: Ayurvedic drugs have been used since ancient times to treat diseases including periodontal diseases. Oral rinses made from ayurvedic medicines are used in periodontal therapy to control bleeding and reduce inflammation. OBJECTIVE: To evaluate the efficacy of herbal preparation (Irimedadi taila) on reduction of plaque induced gingivitis. MATERIALS AND METHODS: A total of 100 volunteers with clinical signs of mild to moderate gingivitis were selected and assigned to Group A (only scaling done) and Group B (scaling along with the use of Irimedadi taila)...
October 11, 2017: Journal of Ayurveda and Integrative Medicine
https://www.readbyqxmd.com/read/29030100/antimicrobial-susceptibility-profiles-of-oral-treponema-species
#6
Kazuko Okamoto-Shibayama, Jin Sekino, Kouki Yoshikawa, Atsushi Saito, Kazuyuki Ishihara
Treponemes occur in the microflora of the dental plaque. Certain Treponema species that are frequently isolated from chronic periodontitis lesions are involved in its initiation and progression. In addition to mechanical instrumentation, antimicrobial agents are used as an adjunctive treatment modality for periodontitis. Despite its importance for successful antimicrobial treatment, information about susceptibility is limited for Treponema species. The aim of this study was to assess the susceptibility of two Treponema denticola strains, Treponema socranskii, and Treponema vincentii to eleven antimicrobial agents...
October 10, 2017: Anaerobe
https://www.readbyqxmd.com/read/29027242/optimal-dose-and-duration-of-amoxicillin-plus-metronidazole-as-an-adjunct-to-non-surgical-periodontal-therapy-a-systematic-review-and-meta-analysis-of-randomized-placebo-controlled-trials
#7
REVIEW
Kelly McGowan, Troy McGowan, Saso Ivanovski
AIM: This systematic review aimed to determine the optimum dose and duration of amoxicillin-plus-metronidazole prescribed as an adjunct to non-surgical treatment of periodontitis. METHODS: Electronic searching identified 376 records, of which 18 were eligible blinded, randomized placebo-controlled trials. The primary outcomes assessed were periodontal pocket depth and clinical attachment level at 3-months, and secondary outcomes were adverse events and compliance...
October 13, 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29026701/how-much-do-italian-patients-in-supportive-periodontal-therapy-know-about-the-role-of-smoking-in-oral-health-and-what-is-their-lifestyle
#8
Roberto Pippi, Maria Vita, Roberto Alvaro, Carlo Di Paolo
OBJECTIVE: The level of awareness of patients receiving supportive periodontal therapy (SPT) concerning the role of smoking as a risk factor for oral health was investigated. MATERIALS AND METHODS: A questionnaire was administered to 158 patients previously treated for periodontitis in four periodontally oriented private dental offices in Rome. The generalized linear model was used to test the simultaneous effect of questions posed to all patients. Fisher's exact test was used to verify significant associations among qualitative variables...
September 2017: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/29026693/platelet-rich-fibrin-a-paradigm-in-periodontal-therapy-a-systematic-review
#9
REVIEW
Umesh Pratap Verma, Rakesh Kumar Yadav, Manisha Dixit, Abhaya Gupta
Periodontal tissue regeneration has always been a challenge for the periodontists owing to its structural complexity. Although with tissue engineering as a growing multidisciplinary field, this aim has partially been fulfilled. In recent years, platelet-rich fibrin (PRF) has gained wide attention for its utilization as a biocompatible regenerative material not only in dental but also in medical fields. The following systematic review has gathered all the currently available in vitro, animal, and clinical studies utilizing PubMed electronic database from January 2006 to August 2016 highlighting PRF for soft and hard tissue regeneration and/or wound healing...
September 2017: Journal of International Society of Preventive & Community Dentistry
https://www.readbyqxmd.com/read/29023390/electrospun-zein-gelatin-scaffold-enhanced-cell-attachment-and-growth-of-human-periodontal-ligament-stem-cells
#10
Fanqiao Yang, Yingling Miao, Yan Wang, Li-Ming Zhang, Xuefeng Lin
Periodontitis is a widespread dental disease affecting 10 to 15% of worldwide adult population, yet the current treatments are far from satisfactory. The human periodontal ligament stem cell is a promising potential seed cell population type in cell-based therapy and tissue regeneration, which require appropriate scaffold to provide a mimic extracellular matrix. Zein, a native protein derived from corn, has an excellent biodegradability, and therefore becomes a hotspot on research and application in the field of biomaterials...
October 12, 2017: Materials
https://www.readbyqxmd.com/read/29017560/effect-of-intra-pregnancy-nonsurgical-periodontal-therapy-on-inflammatory-biomarkers-and-adverse-pregnancy-outcomes-a-systematic-review-with-meta-analysis
#11
Helbert Eustáquio Cardoso da Silva, Cristine Miron Stefani, Nilce de Santos Melo, Adriano de Almeida de Lima, Cassiano Kuchenbecker Rösing, André Luís Porporatti, Graziela De Luca Canto
BACKGROUND: The aim of this systematic review with meta-analysis was to analyze the effects of intra-pregnancy nonsurgical periodontal therapy on periodontal inflammatory biomarkers and adverse pregnancy outcomes. METHODS: On June 5, 2017, we searched PubMed, Cochrane, SCOPUS, Web of Science, LILACS, ProQuest, Open Grey, and Google Scholar databases. Randomized clinical trials in which pregnant women with chronic periodontitis underwent nonsurgical periodontal therapy, compared with an untreated group, tested for inflammatory biomarkers, and followed till delivery were included...
October 10, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/28993821/control-of-plaque-and-gingivitis-by-an-herbal-toothpaste-a-randomised-controlled-study
#12
Alexander Geidel, Monika Krüger, Wieland Schrödl, Holger Jentsch
PURPOSE: To compare the efficacy of an herbal toothpaste with two other chemically active toothpastes regarding plaque and gingivitis control. MATERIALS AND METHODS: Seventy-six (27 females and 49 males, mean age 47.8 years, range 40-58 years) of 84 initial participants with slight and moderate chronic periodontitis used standardised manual toothbrushes and their usual technique for daily manual mechanical plaque control for 24 weeks of supportive periodontal therapy...
2017: Oral Health & Preventive Dentistry
https://www.readbyqxmd.com/read/28988369/retention-of-molars-after-root-resective-therapy-a-retrospective-evaluation-of-up-to-30%C3%A2-years
#13
Hermann Derks, Derk Westheide, Thorsten Pfefferle, Peter Eickholz, Bettina Dannewitz
OBJECTIVES: Long-term retention of teeth and especially molars in function is the ultimate goal of periodontal therapy. Root-resective therapy is a treatment option for molars with advanced furcation involvement, which has been questioned because of the heterogenous success rates published in literature. This study aimed to evaluate long-term results of root-resective treatment over a period of up to 30 years. METHODS: In this retrospective cohort, 90 root-resected molars in 69 patients were examined for 4-30 years (14...
October 7, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28983530/ceramic-laminate-veneers-clinical-procedures-with-a-multidisciplinary-approach
#14
Marco Veneziani
Complex cases with high esthetic needs represent a challenge for clinicians. A multidisciplinary approach is vital to achieve the planned result. New technological devices are needed to facilitate the collaboration between the clinical team members and to develop a fluent and effective diagnostic and therapeutic pathway. This article describes a well-defined protocol for the treatment of complex esthetic cases with the use of ceramic laminate veneers. The protocol involves different branches of dentistry: periodontal therapy, mucogingival surgery, restorative dentistry, orthodontics, and prosthodontics...
2017: International Journal of Esthetic Dentistry
https://www.readbyqxmd.com/read/28975732/a-novel-calcium-accumulating-peptide-gelatin-in-situ-forming-hydrogel-for-enhanced-bone-regeneration
#15
Beom Soo Jo, Yunki Lee, Jin Sook Suh, Yoon Shin Park, Hyun Jung Lee, Jue-Yeon Lee, Jaejin Cho, Gene Lee, Chong Pyoung Chung, Ki Dong Park, Yoon Jeong Park
Bioactive agents, including proteins and peptides, can be loaded into hydrogels to improve bone regenerative capacity with their controlled release. However, the current loading method has focused on physical mixing, which has limited release control. Therefore, alternative conjugation of bioactive agents with hydrogels is highly recommended. Direct chemical conjugation of synthetic peptides containing a functional moiety with a hydrogel would be ideal. Here, we synthesized a bioactive calcium accumulating peptide (CAP) containing a collagen binding motif (CBM), which can induce osteogenic differentiation...
October 4, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28974835/evaluation-of-efficacy-of-surgical-periodontal-therapy-with-the-use-of-bone-graft-in-the-treatment-of-periodontal-intrabony-defects
#16
Mirjana Gojkov-Vukelic, Sanja Hadzic, Enes Pasic
INTRODUCTION: One of the most important goals of periodontitis therapy is the elimination of deep periodontal pockets. In regenerative periodontal therapy, different types of bone grafts, membranes, growth factors, etc. are used to improve regeneration of lost periodontal tissue. The aim of this study was to evaluate the effect of surgical therapy supported by the use of bone replacement material in the treatment of deep intrabony pockets, compared to surgical treatment (flap surgery) without the use of bone replacement in advanced periodontitis...
June 2017: Medical Archives
https://www.readbyqxmd.com/read/28973028/in-vitro-chlorhexidine-release-from-alginate-based-microbeads-for-periodontal-therapy
#17
Malte Scholz, Thomas Reske, Femke Böhmer, Anne Hornung, Niels Grabow, Hermann Lang
Periodontitis is one of the most common infectious diseases globally that, if untreated, leads to destruction of the tooth supporting tissues and finally results in tooth loss. Evidence shows that standard procedures as mechanical root cleaning could be supported by further treatment options such as locally applied substances. Due to gingival crevicular fluid flow, substances are commonly washed out off the periodontal pockets. The evaluation of administration techniques and the development of local drug releasing devices is thus an important aspect in periodontal research...
2017: PloS One
https://www.readbyqxmd.com/read/28972479/analysis-of-the-long-term-clinical-results-of-using-940-%C3%AE-m-diode-laser-in-patients-with-generalized-moderate-chronic-periodontitis
#18
Yu Cherepynska, O Volkova, E Riabokon, T Baglyk
The experience of using a diode laser with a wavelength of 940 μm in the treatment of patients with generalized periodontitis of moderate severity of chronic course is presented. 30 patients were examined, including 17 men (56.6%), and 13 women (43.4%) aged 35-44 with chronic generalized periodontitis of moderate severity. It is concluded that the use of diode laser of 940 μm in the complex therapy of patients with chronic generalized periodontitis of moderate severity is clinically justified and an effective auxiliary method of treatment...
September 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28969294/point-of-care-a-novel-approach-to-periodontal-diagnosis-a-review
#19
REVIEW
Nancy Srivastava, Prathibha Anand Nayak, Shivendra Rana
Periodontal disease, one of the prevalent oral diseases, is characterized by gingival inflammation and periodontal tissue destruction. Diagnosing this disease is challenging to the clinicians as the disease process is discontinuous and shows periods of exacerbation and remission. Traditional diagnostic methods basically tells about the past tissue destruction so new diagnostic methods are required which is able to detect the active state of the disease, determine the future progression and also estimates the response to the therapy, thereby helping in the better clinical management of the patient...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28969266/patient-reported-outcome-assessment-of-periodontal-therapy-a-systematic-review
#20
R M Baiju, Elbe Peter, N O Varghese, P Anju
INTRODUCTION: Patient Reported Outcomes (PROs) are now regarded as a fundamental measure of therapeutic success. Patient's opinion regarding the impact of disease and its treatment is assessed using scales such as Oral Health Related Quality Of Life (OHRQoL) tools. Patient centred outcome assessment is now being considered as a primary outcome measure in clinical trials. AIM: To evaluate whether treatment of periodontal disease could influence OHRQoL based on available literature...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
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