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https://www.readbyqxmd.com/read/28438015/genome-characteristics-of-lactobacillus-fermentum-strain-jdfm216-for-application-as-probiotic-bacteria
#1
Sung Yong Jang, Jaeyoung Heo, Mi Ri Park, Min-Ho Song, Jong Nam Kim, Sung Ho Jo, Do-Youn Jeong, Hak Kyo Lee, Younghoon Kim, Sangnam Oh
Lactobacillus fermentum strain JDFM216, isolated from a Korean infant feces, possesses an enhancement of longevity and immune response on Caenorhabditis elegans host. To explore the molecular characteristics of strain JDFM216, we performed a whole-genome sequencing using PacBio system. The single circular DNA chromosome of 2,076,427 bp was completely assembled and 2,623 encoding sequences were predicted. Phylogenetically featured five genes possibly related to longevity and immune response of host were identified in L...
April 25, 2017: Journal of Microbiology and Biotechnology
https://www.readbyqxmd.com/read/28438006/measurements-and-modeling-of-multipath-interference-at-wavelengths-below-cable-cut-off-in-a-g-654-optical-fiber-span
#2
John D Downie, Jason Hurley, Hector DePedro, Steven Garner, Jeremy Blaker, Aramais Zakharian, Sergey Ten, Greg Mills
Transmission below the cable cut-off wavelength may be a concern in some systems, especially for an optical supervisory channel (OSC) operating below the signal transmission band in systems built with G.654 fiber. In this work, we constructed a cabled span of G.654-compliant fiber and measured the multipath interference (MPI) generated during propagation through the span at a range of wavelengths below the cable cut-offs of the constituent fibers. Measurements were made under a range of conditions including different splice losses and the presence or absence of higher order mode filters placed around the splices...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28438005/comparative-studies-on-the-quality-factors-of-whispering-gallery-modes-and-hybrid-plasmon-photon-modes
#3
Ping Gu, Jiawei Chen, Mingjie Wan, Zhuo Chen, Zhenlin Wang
We theoretically and experimentally investigate the multipolar hybrid plasmon-photon modes supported by a dielectric-metal core-shell resonator consisting of a dielectric core wrapped by a thin silver shell and the whispering-gallery modes in its pure dielectric counterpart (the dielectric sphere with the same size). We theoretically demonstrate that in a certain wavelength range the achievable maximum Q-factors of hybrid modes could be either larger or smaller than that of whispering-gallery modes, depending on the size of the resonator...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437970/cmos-compatible-broadband-co-propagative-stationary-fourier-transform-spectrometer-integrated-on-a-silicon-nitride-photonics-platform
#4
Xiaomin Nie, Eva Ryckeboer, Gunther Roelkens, Roel Baets
We demonstrate a novel type of Fourier Transform Spectrometer (FTS) that can be realized with CMOS compatible fabrication techniques. This FTS contains no moving components and is based on the direct detection of the interferogram generated by the interference of the evanescent fields of two co-propagating waveguide modes. The theoretical analysis indicates that this type of FTS inherently has a large bandwidth (>100 nm). The first prototype that is integrated on a Si<sub>3</sub>N<sub>4</sub> waveguide platform is demonstrated and has an extremely small size (0...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437894/effect-of-anisotropic-electron-momentum-distribution-of-surface-plasmon-on-internal-photoemission-of-a-schottky-hot-carrier-device
#5
Xin-Hao Li, Jeffrey B Chou, Wei Lek Kwan, Asma M Elsharif, Sang-Gook Kim
We recently reported that an Au/TiO<sub>2</sub> photonic crystal device for photochemical energy conversion showed a sub-bandgap photoresponse centered at the surface plasmon polariton (SPP) resonant wavelength of this device. Here we developed a theoretical modeling of the internal photoemission in this device by incorporating the effects of anisotropic hot electron momentum distribution caused by SPP. The influences of interband and intraband transition, anisotropic momentum distribution of hot electrons by SPP are integrated to model the internal quantum efficiency (IQE) of this device...
April 17, 2017: Optics Express
https://www.readbyqxmd.com/read/28437852/a-diagnostic-microdosing-approach-to-investigate-platinum-sensitivity-in-non-small-cell-lung-cancer
#6
Si-Si Wang, Maike Zimmermann, Hongyong Zhang, Tzu-Yin Lin, Michael Malfatti, Kurt Haack, Kenneth W Turteltaub, George D Cimino, Ralph de Vere White, Chong-Xian Pan, Paul T Henderson
The platinum-based drugs cisplatin, carboplatin and oxaliplatin are often used for chemotherapy, but drug resistance is common. The prediction of resistance to these drugs via genomics is a challenging problem since hundreds of genes are involved. A possible alternative is to use mass spectrometry to determine the propensity for cells to form drug-DNA adducts-the pharmacodynamic drug-target complex for this class of drugs. The feasibility of predictive diagnostic microdosing was assessed in non-small cell lung cancer (NSCLC) cell culture and a pilot clinical trial...
April 24, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28437851/fexofenadine-a-putative-in-vivo-p-glycoprotein-probe-fails-to-predict-clearance-of-the-substrate-tacrolimus-in-renal-recipients
#7
Thomas Vanhove, Thomas Bouillon, Henriëtte de Loor, Pieter Annaert, Dirk R J Kuypers
Whether combined use of probe drugs for CYP3A4 and P-glycoprotein can clarify the relative contribution of these proteins to pharmacokinetic variability of a dual substrate like tacrolimus has never been assessed. Seventy renal recipients underwent simultaneous 8-hour pharmacokinetic profiles for tacrolimus, the CYP3A4 probe midazolam and the putative P-glycoprotein probe fexofenadine. Patients were genotyped for polymorphisms in CYP3A5, CYP3A4, ABCB1, ABCC2 and SLCO2B1, -1B1 and 1B3. Carriers of the ABCB1 2677G>A polymorphism displayed lower fexofenadine Cmax (-66%; P=0...
April 24, 2017: Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/28437850/public-perception-of-uncertainties-within-climate-change-science
#8
Vivianne H M Visschers
Climate change is a complex, multifaceted problem involving various interacting systems and actors. Therefore, the intensities, locations, and timeframes of the consequences of climate change are hard to predict and cause uncertainties. Relatively little is known about how the public perceives this scientific uncertainty and how this relates to their concern about climate change. In this article, an online survey among 306 Swiss people is reported that investigated whether people differentiate between different types of uncertainty in climate change research...
April 24, 2017: Risk Analysis: An Official Publication of the Society for Risk Analysis
https://www.readbyqxmd.com/read/28437787/a-comparison-of-three-different-volumes-of-levobupivacaine-for-caudal-block-in-children-undergoing-orchidopexy-and-inguinal-hernia-repair
#9
Vesna Marjanovic, Ivana Budic, Marija Stevic, Dusica Simic
OBJECTIVE: The aim of this study was to compare the efficacy of three different volumes of 0.25% levobupivacaine caudally administered on the effect of intra- and post-operative analgesia in children undergoing orchidopexy and inguinal hernia repair. SUBJECTS AND METHODS: Forty children, aged 1 to 7 years, American Society of Anesthesiologists (ASA) physical status I and II, were randomized into 3 different groups according to the applied volumes of 0.25% levobupivacaine: group 1 (n=13): 0...
April 23, 2017: Medical Principles and Practice: International Journal of the Kuwait University, Health Science Centre
https://www.readbyqxmd.com/read/28437757/abnormal-loading-and-functional-deficits-are-present-in-both-limbs-before-and-after-unilateral-knee-arthroplasty
#10
A J Metcalfe, C J Stewart, N J Postans, P R Biggs, G M Whatling, C A Holt, A P Roberts
Unilateral knee replacement is often followed by a contralateral replacement in time and the biomechanics of the other knee before and after knee replacement remains poorly understood. The aim of this paper is to distinguish the features of arthritic gait in the affected and unaffected legs relative to a normal population and to assess the objective recovery of gait function post-operatively, with the aim of defining patients at risk of poor post-operative function. Twenty patients with severe knee OA but no pain or deformity in any other lower limb joint were compared to twenty healthy subjects of the same age...
April 4, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28437748/rational-and-timely-haemostatic-interventions-following-cardiac-surgery-coagulation-factor-concentrates-or-blood-bank-products
#11
Mariann Tang, Christian Fenger-Eriksen, Per Wierup, Jacob Greisen, Jørgen Ingerslev, Vibeke Hjortdal, Benny Sørensen
BACKGROUND: Cardiac surgery may cause a serious coagulopathy leading to increased risk of bleeding and transfusion demands. Blood bank products are commonly first line haemostatic intervention, but has been associated with hazardous side effect. Coagulation factor concentrates may be a more efficient, predictable, and potentially a safer treatment, although prospective clinical trials are needed to further explore these hypotheses. This study investigated the haemostatic potential of ex vivo supplementation of coagulation factor concentrates versus blood bank products on blood samples drawn from patients undergoing cardiac surgery...
April 5, 2017: Thrombosis Research
https://www.readbyqxmd.com/read/28437742/biological-treatment-of-model-dyes-and-textile-wastewaters
#12
Alicia Paz, Julia Carballo, María José Pérez, José Manuel Domínguez
Previous works conducted in our laboratory, reveled that Bacillus aryabhattai DC100 produce ligninolytic enzymes such as laccases and/or peroxidases, opening new applications in different bioprocesses, including the treatment of disposal residues such as dyestuffs from textile processing industries. This work described the degradation of three commercial model dyes Coomassie Brilliant Blue G-250 (CBB), Indigo Carmine (IC) and Remazol Brilliant Blue R (RBBR) under different culture media and operational conditions...
April 18, 2017: Chemosphere
https://www.readbyqxmd.com/read/28437738/simultaneous-spectrophotometric-determination-of-glimepiride-and-pioglitazone-in-binary-mixture-and-combined-dosage-form-using-chemometric-assisted-techniques
#13
Asmaa A El-Zaher, Ehab F Elkady, Hanan M Elwy, Mahmoud Abo El Makarim Saleh
In the present work, pioglitazone and glimepiride, 2 widely used antidiabetics, were simultaneously determined by a chemometric-assisted UV-spectrophotometric method which was applied to a binary synthetic mixture and a pharmaceutical preparation containing both drugs. Three chemometric techniques - Concentration residual augmented classical least-squares (CRACLS), principal component regression (PCR), and partial least-squares (PLS) were implemented by using the synthetic mixtures containing the two drugs in acetonitrile...
March 14, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28437734/idf-diabetes-atlas-global-estimates-for-the-prevalence-of-diabetes-for-2015-and-2040
#14
K Ogurtsova, J D da Rocha Fernandes, Y Huang, U Linnenkamp, L Guariguata, N H Cho, D Cavan, J E Shaw, L E Makaroff
AIM: To produce current estimates of the national, regional and global impact of diabetes for 2015 and 2040. METHODS: A systematic literature review was conducted to identify data sources on the prevalence of diabetes from studies conducted in the period from 1990 to 2015. An analytic hierarchy process was used to select the most appropriate studies for each country, and estimates for countries without data were modelled using extrapolation from similar countries that had available data...
March 31, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28437726/mercury-correlates-with-altered-corticosterone-but-not-testosterone-or-estradiol-concentrations-in-common-loons
#15
Melinda D Franceschini, David C Evers, Kevin P Kenow, Michael W Meyer, Mark Pokras, L Michael Romero
We investigated the relation between environmental mercury exposure and corticosterone concentrations in free-living adult common loons (Gavia immer). We determined blood and feather mercury concentrations and compared them to testosterone, estradiol, and stress-induced plasma corticosterone concentrations. Although neither testosterone nor estradiol correlated with Hg levels, there was a robust positive relation between blood Hg and stress-induced corticosterone concentrations in males, but not in females...
April 21, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28437718/nontargeted-metabolomics-approach-for-the-differentiation-of-cultivation-ages-of-mountain-cultivated-ginseng-leaves-using-uhplc-qtof-ms
#16
Xiangwei Chang, Juanjuan Zhang, Dekun Li, Dazheng Zhou, Yuling Zhang, Jincheng Wang, Bing Hu, Aichun Ju, Zhengliang Ye
The adulteration or falsification of the cultivation age of mountain cultivated ginseng (MCG) has been a serious problem in the commercial MCG market. To develop an efficient discrimination tool for the cultivation age and to explore potential age-dependent markers, an optimized ultra high-performance liquid chromatography/quadrupole time-of-flight mass spectrometry (UHPLC/QTOF-MS)-based metabolomics approach was applied in the global metabolite profiling of 156 MCG leaf (MGL) samples aged from 6 to 18 years...
April 13, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28437705/both-heavy-metal-amendment-of-soil-and-aphid-infestation-increase-cd-and-zn-concentrations-in-phloem-exudates-of-a-metal-hyperaccumulating-plant
#17
Clemens Stolpe, Franziska Giehren, Ute Krämer, Caroline Müller
Plants that are able to hyperaccumulate heavy metals show increased concentrations of these metals in their leaf tissue. However, little is known about the concentrations of heavy metals and of organic defence metabolites in the phloem sap of these plants in response to either heavy metal-amendment of the soil or biotic challenges such as aphid-infestation. In this study, we investigated the effects of heavy metal-exposure and of aphid-infestation on phloem exudate composition of the metal hyperaccumulator species Arabidopsis halleri L...
April 21, 2017: Phytochemistry
https://www.readbyqxmd.com/read/28437693/an-assessment-of-the-social-cognitive-predictors-of-exclusive-breastfeeding-behavior-using-the-health-action-process-approach
#18
J L Martinez-Brockman, F M Shebl, N Harari, R Pérez-Escamilla
RATIONALE: In the United States rates of exclusive breastfeeding duration remain exceedingly low. Exclusive breastfeeding is a complex learned behavior that is influenced by social cognitive, interpersonal, and structural factors. Interventions are needed that address factors at multiple levels of the social-ecological model. This study was designed to examine the social cognitive predictors of exclusive breastfeeding behavior in a sample of low-income women attending the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC) breastfeeding peer counseling program and enrolled in the Lactation Advice Through Texting Can Help (LATCH) study...
April 12, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28437688/application-of-near-infrared-spectroscopy-for-the-rapid-quality-assessment-of-radix-paeoniae-rubra
#19
Hao Zhan, Jing Fang, Liying Tang, Hongjun Yang, Hua Li, Zhuju Wang, Bin Yang, Hongwei Wu, Meihong Fu
Near-infrared (NIR) spectroscopy with multivariate analysis was used to quantify gallic acid, catechin, albiflorin, and paeoniflorin in Radix Paeoniae Rubra, and the feasibility to classify the samples originating from different areas was investigated. A new high-performance liquid chromatography method was developed and validated to analyze gallic acid, catechin, albiflorin, and paeoniflorin in Radix Paeoniae Rubra as the reference. Partial least squares (PLS), principal component regression (PCR), and stepwise multivariate linear regression (SMLR) were performed to calibrate the regression model...
April 20, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28437681/predicting-wellbeing-among-people-with-epilepsy-using-illness-cognitions
#20
Kirstie A Salter, Kirsty N Prior, Malcolm J Bond
OBJECTIVE: This study sought to examine the synergistic contribution of illness-related perceptions (stigma, severity, and threat) and illness behavior to wellbeing among people with epilepsy. Poorer wellbeing was expected among those who perceived greater stigma, illness severity, and threat and had more extreme illness behavior. METHODS: Individuals with a diagnosis of epilepsy (N=210), recruited through local and online support groups, completed a questionnaire comprising demographic and epilepsy-specific information, and validated measures of illness perceptions and behavior, epilepsy-related quality of life, and general psychological health...
April 21, 2017: Epilepsy & Behavior: E&B
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