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https://www.readbyqxmd.com/read/29782813/actinomycotic-osteomyelitis-of-the-mandible-diagnosed-using-matrix-assisted-laser-desorption-ionization-time-of-flight-mass-spectrometry-a-case-report
#1
Shinsuke Yamamoto, Hiroshi Takegawa, Naoki Taniike, Toshihiko Takenobu
Actinomycosis is a rare, chronic, slowly progressive granulomatous disease caused by filamentous gram-positive anaerobic bacteria from the Actinomycetaceae family (genus Actinomyces). It has become a rare condition because of the widespread use of antibiotics. When clinical symptoms are not typical, diagnosis of this condition becomes difficult. This report describes a case involving an 82-year-old woman who was diagnosed with actinomycotic osteomyelitis of the mandible using matrix assisted laser desorption ionization-time-of-flight mass spectrometry (MALDI-TOF MS)...
April 26, 2018: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29782700/nonionic-dendritic-and-carbohydrate-based-amphiphiles-self-assembly-and-transport-behavior
#2
Suchita Prasad, Katharina Achazi, Boris Schade, Rainer Haag, Sunil K Sharma
Herein, a new series of non-ionic dendritic and carbohydrate based amphiphiles is synthesized employing biocompatible starting materials and studied for supramolecular aggregate formation in aqueous solution. The dendritic amphiphiles 12 and 13 possessing poly(glycerol) [G2.0] as hydrophilic unit and C-10 and C-18 hydrophobic alkyl chains, respectively, exhibit low critical aggregation concentration (CAC) in the order of 10-5 m and hydrodynamic diameters in the 8-10 nm range and supplemented by cryogenic transmission electron microscopy...
May 21, 2018: Macromolecular Bioscience
https://www.readbyqxmd.com/read/29782676/composition-graded-cesium-lead-halide-perovskite-nanowires-with-tunable-dual-color-lasing-performance
#3
Ling Huang, Qinggang Gao, Ling-Dong Sun, Hao Dong, Shuo Shi, Tong Cai, Qing Liao, Chun-Hua Yan
Cesium lead halide (CsPbX3 ) perovskite has emerged as a promising low-threshold multicolor laser material; however, realizing wavelength-tunable lasing output from a single CsPbX3 nanostructure is still constrained by integrating different composition. Here, the direct synthesis of composition-graded CsPbBrx I3- x nanowires (NWs) is reported through vapor-phase epitaxial growth on mica. The graded composition along the NW, with an increased Br/I from the center to the ends, comes from desynchronized deposition of cesium lead halides and temperature-controlled anion-exchange reaction...
May 21, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29782671/enhanced-performance-of-a-molecular-photoacoustic-imaging-agent-by-encapsulation-in-mesoporous-silicon-nanoparticles
#4
Jinyoung Kang, Dokyoung Kim, Junxin Wang, Yunho Han, Jonathan M Zuidema, Ali Hariri, Ji-Ho Park, Jesse V Jokerst, Michael J Sailor
Photoacoustic (PA) imaging allows visualization of the physiology and pathology of tissues with good spatial resolution and relatively deep tissue penetration. The method converts near-infrared (NIR) laser excitation into thermal expansion, generating pressure transients that are detected with an acoustic transducer. Here, we find that the response of the PA contrast agent indocyanine green (ICG) can be enhanced 17-fold when it is sealed within a rigid nanoparticle. ICG encapsulated in particles composed of porous silicon (pSiNP), porous silica, or calcium silicate all show greater PA contrast relative to equivalent quantities of free ICG, with the pSiNPs showing the strongest enhancement...
May 21, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29782617/patient-specific-neurosurgical-phantom-assessment-of-visual-quality-accuracy-and-scaling-effects
#5
Felipe Wilker Grillo, Victor Hugo Souza, Renan Hiroshi Matsuda, Carlo Rondinoni, Theo Zeferino Pavan, Oswaldo Baffa, Helio Rubens Machado, Antonio Adilton Oliveira Carneiro
Background: Training in medical education depends on the availability of standardized materials that can reliably mimic the human anatomy and physiology. One alternative to using cadavers or animal bodies is to employ phantoms or mimicking devices. Styrene-ethylene/butylene-styrene (SEBS) gels are biologically inert and present tunable properties, including mechanical properties that resemble the soft tissue. Therefore, SEBS is an alternative to develop a patient-specific phantom, that provides real visual and morphological experience during simulation-based neurosurgical training...
2018: 3D Print Med
https://www.readbyqxmd.com/read/29782336/a-review-of-small-incision-lenticule-extraction-complications
#6
Ronald R Krueger, Caio S Meister
PURPOSE OF REVIEW: As a flapless procedure, SMILE brings benefits to refractive surgery, such as lower corneal biomechanical impact, less dry eye risk and less stromal bed exposure. However, the longer learning curve can be a risk factor for complications. This article aims to discuss SMILE complications and proposes a categorized analysis of occurrences, dividing into two groups: intraoperative and postoperative complications. Among intraoperative, we also suggest a subdivision between those related to the laser (lenticule construction), tissue separation (lenticule dissection) and tissue removal (lenticule extraction)...
May 17, 2018: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/29782309/in-memoriam-assistant-professor-kre%C3%A5-imir-kostovi%C3%A4-md-phd-16-october-1969-15-october-2017
#7
Branka Marinović
On a Sunday afternoon almost six months ago, we were deeply moved by the news that our Krešimir is no longer with us. The sad news spread from Sarajevo with the speed only most horrible and saddest news can achieve. And everybody who was reached by these news wondered whether it was possible and whether it was true. Because our professor Kostović left us a day before his 48th birthday. Krešimir Kostović was born on the 16th October 1969 in Zagreb, where he completed primary and secondary education. He enrolled at the University of Zagreb School of Medicine in 1988, and got his medical degree in 1995...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29782307/cutaneous-manifestations-of-tuberous-sclerosis
#8
Mirjana Bakić, Marina Ratković, Branka Gledović, Balsa Vujović, Danilo Radunović, Vera Babić, Vladimir Prelević
Dear Editor, Tuberous sclerosis (TS) is an autosomal dominant multisystem disease, which occurs due to genetically determined hyperplasia of ectodermal and mesodermal cells. Clinical manifestations present on the skin and in the nervous system, kidneys, heart, and other organs. Recent studies estimate the incidence of TS at 1/6000 to 1/10,000 live births, and a prevalence in the general population of approximately 1 in 20,000 (1). There are two different genetic loci responsible for TS: 9q34 (TSC1-hamartin) and 16p13...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29782304/role-of-in-vivo-reflectance-confocal-microscopy-in-the-analysis-of-melanocytic-lesions
#9
Elena-Daniela Serban, Francesca Farnetani, Giovanni Pellacani, Maria Magdalena Constantin
Worldwide melanoma incidence and mortality are increasing (1). Despite the ongoing research, advanced melanoma is still incurable; therefore, the most appropriate solution seems to be early detection combined with complete surgical excision (2). Since the diagnostic protocol of suspicious lesions includes a complete excision with safety margins (2), the problem of unnecessary scarring is significant. The real challenge in this case is to have a properly formulated diagnosis before acquiring a biopsy. Currently available non-invasive techniques are coherence tomography, digital dermoscopy, and reflectance confocal microscopy...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29782301/lymphangioma-circumscriptum-post-radiotherapy-for-penile-cancer-treated-with-co%C3%A2-laser
#10
Dietmar Schulz, Andreas Lein, Ancuta Proca Nicula, Katrin Schierle, Caius Solovan
Lymphangioma circumscriptum (LC) is a rare, benign condition, predominantly characterized by the malformation of lymphatic skin vessels. Its onset may be congenital or due to secondary causes such as radiotherapy, infections, or surgical procedures. We present the case of a 55-year-old patient with a pathologic history of squamous cell carcinoma of the penis followed by radical penectomy. Due to metastasis to the locoregional lymph nodes, the entire affected area was subsequently treated with radiation therapy, receiving a total dose of 55...
April 2018: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/29782148/accelerated-bone-regeneration-by-nitrogen-doped-carbon-dots-functionalized-with-hydroxyapatite-nanoparticles
#11
Deepak Kumar Khajuria, Vijay Bhooshan Kumar, Dana Gigi, Aharon Gedanken, David Karasik
We investigated the osteogenic potential of nitrogen doped carbon dots (NCDs) conjugated with hydroxyapatite (HA) nanoparticles on the MC3T3-E1 osteoblast cell functions and in a zebrafish (ZF) jaw bone regeneration (JBR) model. The NCDs-HA nanoparticles were fabricated by hydrothermal cum co-precipitation technique. The surface structures of NCDs-HA nanoparticles were characterized by XRD, FTIR, UV-Vis, and laser fluorescent spectroscopy, SEM, TEM, EDS, and NMR analysis. The TEM data confirmed that the NCDs are well conjugated on the HA nanoparticle surfaces...
May 21, 2018: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/29782140/fluorescent-labeling-of-the-nuclear-envelope-by-localizing-gfp-on-the-inner-nuclear-membrane
#12
Toshiyuki Taniyama, Natsumi Tsuda, Shinji Sueda
The nuclear envelope (NE) is a double membrane that segregates nuclear components from the cytoplasm in eukaryote cells. It is well-known that the NE undergoes a breakdown and reformation during mitosis in animal cells. However, the detailed mechanisms of the NE dynamics are not yet fully understood. Here, we propose a method for the fluorescent labeling of the NE in living cells, which enables the tracing of the NE dynamics during cell division under physiological conditions. In our method, labeling of the NE is accomplished by fixing green fluorescent protein carrying the nuclear localization signal on the inner nuclear membrane based on a unique biotinylation reaction from the archaeon Sulfolobus tokodaii...
May 21, 2018: ACS Chemical Biology
https://www.readbyqxmd.com/read/29782050/sequels-to-tattoo-removal-by-caustic-products
#13
K Hutton Carlsen, J Serup
BACKGROUND: Caustic products are used as affordable alternatives to laser removal of tattoos. OBJECTIVE: Describe a series of patients with sequels after tattoo removal by caustic products. METHODS: 11 patients with complications referred from 2013 to 2017 were studied. Objective findings, sequels, corrective treatments, cost and psychological aspects were obtained. Numeric Rating Scale (NRS, score 10 extremely dissatisfied) was used to describe patient satisfaction with tattoos before and after removal...
May 21, 2018: Skin Research and Technology
https://www.readbyqxmd.com/read/29781994/a-drosophila-in-vivo-injury-model-for-studying-neuroregeneration-in-the-peripheral-and-central-nervous-system
#14
Dan Li, Feng Li, Pavithran Guttipatti, Yuanquan Song
The regrowth capacity of damaged neurons governs neuroregeneration and functional recovery after nervous system trauma. Over the past few decades, various intrinsic and extrinsic inhibitory factors involved in the restriction of axon regeneration have been identified. However, simply removing these inhibitory cues is insufficient for successful regeneration, indicating the existence of additional regulatory machinery. Drosophila melanogaster, the fruit fly, shares evolutionarily conserved genes and signaling pathways with vertebrates, including humans...
May 5, 2018: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/29781929/femtosecond-laser-assisted-graft-preparation-for-descemet-membrane-endothelial-keratoplasty
#15
Hamish D McKee, Vishal Jhanji
PURPOSE: To describe a technique of using a femtosecond laser to assist with graft preparation for Descemet membrane endothelial keratoplasty (DMEK). METHODS: A femtosecond laser was used to assist in graft preparation for 3 DMEK procedures. The donor cornea is mounted on a proprietary artificial anterior chamber. A partial thickness deep circular cut is made with the femtosecond laser through the endothelium, Descemet membrane, and posterior stroma. Graft preparation is then completed without the use of a corneal trephine...
May 16, 2018: Cornea
https://www.readbyqxmd.com/read/29781903/treatment-of-corticosteroid-induced-hypopigmentation-using-fractional-carbon-dioxide-laser
#16
Margaret C Green, Michael S Tracey, John P Trafeli, John Paul Trafeli
No abstract text is available yet for this article.
May 16, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29781902/endovenous-thermal-ablation-of-recurrent-varicose-veins-due-to-residual-great-saphenous-venous-insufficiency-after-saphenous-venous-surgery-a-comparative-study
#17
Jin Ho Hwang, Sang Woo Park, Il Soo Chang, Ki Hyun Kim, Ji Hun Kang
BACKGROUND: Redo surgery for recurrent varicose veins of the great saphenous vein (GSV) is technically more challenging than the initial surgery. OBJECTIVE: To compare 980 and 1,470-nm endovenous laser ablation (EVLA) and radiofrequency ablation (RFA) for the treatment of residual GSV insufficiency after saphenofemoral ligation ± stripping. MATERIALS AND METHODS: Thirty-seven limbs in 29 patients with recurrent varicose veins were retrospectively evaluated...
May 16, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29781900/concomitant-use-of-1-550-nm-nonablative-fractional-laser-with-low-dose-isotretinoin-for-the-treatment-of-acne-vulgaris-in-asian-patients-a-randomized-split-face-controlled-study
#18
Jun Xia, Guanglei Hu, Die Hu, Songmei Geng, Weihui Zeng
BACKGROUND: Nonablative fractional laser (NAFL) has been shown to improve the appearance of inflammatory acne and acne scars. Isotretinoin is effective for the treatment of moderate-to-severe cases of recalcitrant acne. However, the recommended dose of isotretinoin can have profound effects. OBJECTIVE: To investigate the clinical efficacy and safety of performing NAFL treatment in patients with moderate-to-severe acne vulgaris under treatment with low-dose oral isotretinoin...
May 16, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29781835/deep-learning-classifier-with-an-ultra-wide-field-scanning-laser-ophthalmoscope-detects-glaucoma-visual-field-severity
#19
Masumoto Hiroki, Hitoshi Tabuchi, Shunsuke Nakakura, Ishitobi Naofumi, Masayuki Miki, Enno Hiroki
PURPOSE: To evaluate the accuracy of detecting glaucoma visual field defect severity using deep-learning classifier (DL) with an ultra-wide-field scanning laser ophthalmoscope. METHODS: One eye of 982 open angle glaucoma (OAG) patients and 417 healthy eyes were enrolled. We categorized glaucoma patients into three groups according to the glaucoma visual field damage (Humphrey Field Analyzer 24-2 program) (early; -6▒dB (mean deviation) or better, moderate; between -6 and -12▒dB, and severe as mean deviation of -12▒dB or worse)...
May 17, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/29781625/vertically-emitting-indium-phosphide-nanowire-lasers
#20
Wei-Zong Xu, Fang-Fang Ren, Dimitars Jevtics, Antonio Hurtado, Li Li, Qian Gao, Jiandong Ye, Fan Wang, Benoit Guilhabert, Lan Fu, Hai Lu, Rong Zhang, Hark Hoe Tan, Martin Dawson, Chennupati Jagadish
Semiconductor nanowire (NW) lasers have attracted considerable research effort given their excellent promise for nanoscale photonic sources. However, NW lasers currently exhibit poor directionality and high threshold gain, issues critically limiting their prospects for on-chip light sources with extremely reduced footprint and efficient power consumption. Here, we propose a new design and experimentally demonstrate a vertically emitting indium phosphide (InP) NW laser structure showing high emission directionality and reduced energy requirements for operation...
May 21, 2018: Nano Letters
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