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https://www.readbyqxmd.com/read/28227998/monitoring-of-thermal-treatment-by-linearly-chirped-fiber-bragg-grating-sensors-feasibility-assessment-during-laser-ablation-on-ex-vivo-liver
#1
F Napoleoni, M Caponera, A Polimadei, D Tosi, P Saccomandi, E Schena, F Napoleoni, M Caponera, A Polimadei, D Tosi, P Saccomandi, E Schena, A Polimadei, P Saccomandi, D Tosi, F Napoleoni, F Schena
In this work a spatially-resolved fiber optic temperature sensor has been characterized in a wide range of gradient applied on its active area (from -35 °C to +35 °C). Preliminary experiments to assess its feasibility for application in laser ablation have been performed. The sensor under test is a linearly chirped fiber Bragg grating (FBG), with 1.5 cm-length of active area. It can be considered as a chain of several FBGs, each able to sense local temperature. The sensor response to the gradient has been analyzed in terms of its spectrum width (full width at half maximum)...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227686/novel-modular-2-dof-microsurgical-forceps-for-transoral-laser-microsurgeries-ergonomic-design-and-preliminary-evaluation
#2
Manish Chauhan, Giacinto Barresi, Nikhil Deshpande, Darwin G Caldwell, Leonardo S Mattos, Manish Chauhan, Giacinto Barresi, Nikhil Deshpande, Darwin G Caldwell, Leonardo S Mattos, Darwin G Caldwell, Giacinto Barresi, Leonardo S Mattos, Nikhil Deshpande, Manish Chauhan
Transoral Laser Microsurgeries (TLM) demand a great level of control and precision in intraoperative tissue manipulation. The optimal eradication of the diseased tissue is possible only with coordinated control of the laser aiming for incision and the microsurgical tools for orienting and stretching the tissue. However, the traditional microsurgical tools are long, single purpose, one degree-of-freedom (DOF), rigid tools with small range of motion and a normal grasping handle inducing non-ergonomic usage. This paper presents a novel, modular microsurgical tool to overcome the challenges of the traditional tools and improve the surgeon-tool usage experience...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227672/robot-assisted-microsurgical-forceps-with-haptic-feedback-for-transoral-laser-microsurgery
#3
Nikhil Deshpande, Manish Chauhan, Claudio Pacchierotti, Domenico Prattichizzo, Darwin G Caldwell, Leonardo S Mattos, Nikhil Deshpande, Manish Chauhan, Claudio Pacchierotti, Domenico Prattichizzo, Darwin G Caldwell, Leonardo S Mattos, Darwin G Caldwell, Leonardo S Mattos, Nikhil Deshpande, Domenico Prattichizzo, Manish Chauhan, Claudio Pacchierotti
In this paper, a novel, motorized, multi-degrees-of-freedom (DoF), microsurgical forceps tool is presented, which is based on a master-slave teleoperation architecture. The slave device is a 7-DoF manipulator with: (i) 6-DoF positioning and orientation, (ii) 1 open/close gripper DoF; and (iii) an integrated force/torque sensor for tissue grip-force measurement. The master device is a 7-DoF haptic interface which teleoperates the slave device, and provides haptic feedback in its gripper interface. The combination of the device and the surgeon interface replaces the manual, hand-held device providing easy-to-use and ergonomic tissue control, simplifying the surgical tasks...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227671/imquant-an-image-based-fluorescence-reader-for-quantitative-lateral-flow-immunoassays
#4
Kaushik Basak Chowdhury, Jayaraj Joseph, Jayaraman Kiruthi Vasan, Mohanasankar Sivaprakasam, Kaushik Basak Chowdhury, Jayaraj Joseph, Jayaraman Kiruthi Vasan, Mohanasankar Sivaprakasam, Jayaraman Kiruthi Vasan, Mohanasankar Sivaprakasam, Jayaraj Joseph, Kaushik Basak Chowdhury
Fluorescence immunoassays (FIA) have strong potential in enabling rapid quantitative immunological testing at point of care. Existing state of the art instruments employ laser scanning of FIA test kits, which require the use of electromechanical systems, making the instrument bulky, heavy and less reliable in the long term. There is a growing need for an extremely compact and reliable, motion-free, automated reader for accurate quantification of immunoassays. Here, we present ImQuant, an image based FIA reader with integrated monochromatic excitation source, optical filtering and real time image capture, assisted with an intuitive graphical user interface...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227669/green-lasers-are-beyond-power-limits-mandated-by-safety-standards
#5
M H Lee, K Fox, S Goldwasser, D W M Lau, B Aliahmad, M Sarossy, M H Lee, K Fox, S Goldwasser, D W M Lau, B Aliahmad, M Sarossy, B Aliahmad, M H Lee, K Fox, D W M Lau, M Sarossy, S Goldwasser
There has been an increasing number of reports of people losing vision from laser exposure from pocket laser pointers despite the safety limit of 1 milliwatt (1mW) imposed by the Australian government. We hypothesize that this is because commercially available red and green laser pointers are exceeding their labeled power outputs. We tested the power outputs of 4 red and 4 green lasers which were purchased for less than AUD$30 each. The average of 10 measurements was recorded for each laser. We found that 3 out of 4 red lasers conformed to the 1mW safety standard; in contrast, all of the green lasers exceeded this limit, with one of the lasers recording an output of 127...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227507/efficient-assembly-of-multi-color-fiberless-optoelectrodes-with-on-board-light-sources-for-neural-stimulation-and-recording
#6
K Kampasi, J Seymour, E Stark, G Buzsaki, K D Wise, E Yoon, K Kampasi, J Seymour, E Stark, G Buzsaki, K D Wise, E Yoon, E Yoon, K Kampasi, J Seymour, G Buzsaki, E Stark, K D Wise
Fiberless optoelectrodes are an emerging tool to enable brain circuit mapping by providing precise optical modulation and electrical monitoring of many neurons. While optoelectrodes having an on-board light source offer compact and optically efficient device solutions, many of them fail to provide robust thermal and electrical design to fully exploit the recording capabilities of the device. In this work, we present a novel fiberless multicolor optoelectrode solution, which meets the optical and thermal design requirements of an in vivo neural optoelectrode and offers potential for low-noise neural recording...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227368/pulsecam-high-resolution-blood-perfusion-imaging-using-a-camera-and-a-pulse-oximeter
#7
Mayank Kumar, James Suliburk, Ashok Veeraraghavan, Ashutosh Sabharwal, Mayank Kumar, James Suliburk, Ashok Veeraraghavan, Ashutosh Sabharwal, Mayank Kumar, James Suliburk, Ashok Veeraraghavan, Ashutosh Sabharwal
Measuring blood perfusion is important in medical care as an indicator of injury and disease. However, currently available devices to measure blood perfusion like laser Doppler flowmetry are bulky, expensive, and cumbersome to use. An alternative low-cost and portable camera-based blood perfusion measurement system has recently been proposed, but such camera-only system produces noisy low-resolution blood perfusion maps. In this paper, we propose a new multi-sensor modality, named PulseCam, for measuring blood perfusion by combining a traditional pulse oximeter with a video camera in a unique way to provide low noise and high-resolution blood perfusion maps...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227361/kinect2-respiratory-movement-detection-study
#8
Sandy Rihana, Elie Younes, Dimitris Visvikis, Hadi Fayad, Sandy Rihana, Elie Younes, Dimitris Visvikis, Hadi Fayad, Sandy Rihana, Elie Younes, Dimitris Visvikis, Hadi Fayad
Radiotherapy is one of the main cancer treatments. It consists in irradiating tumor cells to destroy them while sparing healthy tissue. The treatment is planned based on Computed Tomography (CT) and is delivered over fractions during several days. One of the main challenges is replacing patient in the same position every day to irradiate the tumor volume while sparing healthy tissues. Many patient positioning techniques are available. They are both invasive and not accurate performed using tattooed marker on the patient's skin aligned with a laser system calibrated in the treatment room or irradiating using X-ray...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227357/experimental-evaluation-of-the-accuracy-at-the-c-arm-pose-estimation-with-x-ray-images
#9
Sabine Thurauf, Florian Vogt, Oliver Hornung, Mario Korner, M Ali Nasseri, Alois Knoll, Sabine Thurauf, Florian Vogt, Oliver Hornung, Mario Korner, M Ali Nasseri, Alois Knoll, Sabine Thurauf, Alois Knoll, Mario Korner, Florian Vogt, Oliver Hornung, M Ali Nasseri
C-arm X-ray systems need a high spatial accuracy for applications like cone beam computed tomography and 2D/3D overlay. One way to achieve the needed precision is a model-based calibration of the C-arm system. For such a calibration a kinematic and dynamic model of the system is constructed whose parameters are computed by pose measurements of the C-arm. Instead of common measurement systems used for a model-based calibration for robots like laser trackers, we use X-ray images of a calibration phantom to measure the C-arm pose...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227286/indirect-measurement-of-the-carotid-arterial-pressure-from-vibrocardiographic-signal-calibration-of-the-waveform-and-comparison-with-photoplethysmographic-signal
#10
L Casacanditella, G Cosoli, S Casaccia, E P Tomasini, L Scalise, L Casacanditella, G Cosoli, S Casaccia, E P Tomasini, L Scalise, G Cosoli, S Casaccia, E P Tomasini, L Casacanditella, L Scalise
The detection of arterial Blood Pressure waveform provides important information about the subject health status. Laser Doppler Vibrometry (LDV) is a non-contact technique with high sensitivity able to detect mechanical movements of the arterial wall; several previous studies have shown that LDV is able to characterize cardiac activity. Photoplethysmogram (PPG) quantifies the digital volume artery pulse, which has been demonstrated to be closely related to the pressure signal measured by an arterial tonometer...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227240/measurement-of-shank-angle-during-stance-using-laser-range-finders
#11
Pouya Amiri, Luke J MacLean, Robert E Kearney, Pouya Amiri, Luke J MacLean, Robert E Kearney, Robert E Kearney, Luke J MacLean, Pouya Amiri
Ankle joint stiffness, the dynamic relationship between the joint angle and the torque acting about it, plays an important role in the control of upright stance. In order to identify the contribution of ankle joint stiffness to stance control, ankle joint must be perturbed externally. One way to do this is to displace the foot that will cause shank movement. For identification, the ankle angle must be measured with high accuracy, for which we need to measure both foot and shank angles. However, most motion capture systems do not have the resolution and accuracy needed to measure the small ankle joint movements that occur during stance...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28227100/a-double-sided-fabrication-process-for-intrafascicular-parylene-c-based-electrode-arrays
#12
M Mueller, C Boehler, J Jaeger, M Asplund, T Stieglitz, M Mueller, C Boehler, J Jaeger, M Asplund, T Stieglitz, T Stieglitz, C Boehler, M Mueller, M Asplund, J Jaeger
After the development of a single-sided fabrication process for intrafascicular parylene C based electrode arrays tests showed that an increase in integration density can only be achieved by a double-side process. The process uses 25 μm thick platinum iridium foil, which is thinned down with the laser and sandwiched between two 10 μm thick parylene C layers. Utilizing a picosecond laser (355 nm Nd:YVO4) it was possible to fabricate 40 μm thick electrodes that can be implanted directly in the nerve without relying on additional support layers like chitosan or silk...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226931/3d-endoscope-system-using-doe-projector
#13
Ryo Furukawa, Yoji Sanomura, Shinji Tanaka, Shigeto Yoshida, Ryusuke Sagawa, Marco Visentini-Scarzanella, Hiroshi Kawasaki, Ryo Furukawa, Yoji Sanomura, Shinji Tanaka, Shigeto Yoshida, Ryusuke Sagawa, Marco Visentini-Scarzanella, Hiroshi Kawasaki, Marco Visentini-Scarzanella, Yoji Sanomura, Shinji Tanaka, Ryo Furukawa, Ryusuke Sagawa, Hiroshi Kawasaki, Shigeto Yoshida
For effective in situ endoscopic diagnosis and treatment, size measurement and shape characterization of lesions, such as tumors, is important. For this purpose, in the past we have developed a range of 3D endoscopic systems based on active stereo to measure the shape and size of living tissues. In those works, the main shortcoming was that the target area could only be reconstructed at a specific distance from the scope because of off-focus blurring effects and aberrations in the periphery of the field of view...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226849/investigation-of-the-ca-2-response-of-human-hnt-astrocytes-to-laser-removal-of-cellular-processes
#14
Brad J Raos, E Scott Graham, Charles P Unsworth, Brad J Raos, E Scott Graham, Charles P Unsworth, Charles P Unsworth, Brad J Raos, E Scott Graham
We demonstrate, for the first time, UV laser ablative microsurgery as a method for pruning astrocytic processes from live hNT astrocytic networks in vitro. Calcium fluorescence imaging was used to evaluate the cellular response to process ablation. The results showed that ablation of astrocyte processes induced an immediate increase in intracellular calcium level which propagated through the cells cytoplasm as a wave originating from the ablation site. The increased intracellular calcium dissipated from the body of the cell but remained high in the vicinity of the ablation site...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226510/microwave-to-near-infrared-conversion-with-a-millimeter-scale-wireless-laser-for-activating-molecular-transducers
#15
Anthony Romano, John S Ho, Anthony Romano, John S Ho, Anthony Romano, John S Ho
Light-activated molecular transducers enable precise manipulation of biological processes and are thus powerful tools for studying or treating disease. Their use in vivo, however, is currently limited by the low penetration of light through biological tissue. While electromagnetic fields at microwave frequencies can penetrate thick tissue, they do not provide direct control over molecular transducers. Here, we describe a miniaturized, wirelessly powered laser capable of delivering high intensity near-infrared light in tissue...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226498/a-diaper-embedded-disposable-nitrite-sensor-with-integrated-on-board-urine-activated-battery-for-uti-screening
#16
W Yu, W Seo, T Tan, B Jung, B Ziaie, W Yu, W Seo, T Tan, B Jung, B Ziaie, B Ziaie, W Seo, W Yu, T Tan, B Jung
This paper reports a low-cost solution to the early detection of urinary nitrite, a common surrogate for urinary tract infection (UTI). We present a facile method to fabricate a disposable and flexible colorimetric [1] nitrite sensor and its urine-activated power source [2] on a hydrophobic (wax) paper through laser-assisted patterning and lamination. Such device, integrated with interface circuitry and a Bluetooth low energy (BLE) module can be embedded onto a diaper, and transmit semi-quantitative UTI monitoring information in a point-of-care and autonomous fashion...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226480/eeg-based-image-encryption-via-quantum-walks
#17
N Rawat, Y Shin, I Balasingham, N Rawat, Y Shin, I Balasingham, I Balasingham, N Rawat, Y Shin
An electroencephalogram (EEG) based image encryption combined with Quantum walks (QW) is encoded in Fresnel domain. The computational version of EEG randomizes the original plaintext whereas QW can serve as an excellent key generator due to its inherent nonlinear chaotic dynamic behavior. First, a spatially coherent monochromatic laser beam passes through an SLM, which introduces an arbitrary EEG phase-only mask. The modified beam is collected by a CCD. Further, the intensity is multiply with the QW digitally...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28226203/characteristic-changes-in-decidual-gene-expression-signature-in-spontaneous-term-parturition
#18
Haidy El-Azzamy, Andrea Balogh, Roberto Romero, Yi Xu, Christopher LaJeunesse, Olesya Plazyo, Zhonghui Xu, Theodore G Price, Zhong Dong, Adi L Tarca, Zoltan Papp, Sonia S Hassan, Tinnakorn Chaiworapongsa, Chong Jai Kim, Nardhy Gomez-Lopez, Nandor Gabor Than
Background: The decidua has been implicated in the "terminal pathway" of human term parturition, which is characterized by the activation of pro-inflammatory pathways in gestational tissues. However, the transcriptomic changes in the decidua leading to terminal pathway activation have not been systematically explored. This study aimed to compare the decidual expression of developmental signaling and inflammation-related genes before and after spontaneous term labor in order to reveal their involvement in this process...
February 22, 2017: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/28225874/experimental-burns-comparison-between-silver-sulfadiazine-and-photobiomodulation
#19
Mariana Teixeira Gomes, Gabriela Russo Soeiro Campos, Natália Piccolo, Cristiane Miranda França, Guelton Hirano Guedes, Fabio Lopes, Renata A Belotto, Christiane Pavani, Rafael do Nascimento de Lima, Daniela de Fátima Teixeira da Silva
OBJECTIVE: To analyze morphological characteristics and organization of the collagen fibers of third degree burns from scalding compared to laser therapy and silver sulfadiazine, the latter considered as the gold standard. METHOD: Were selected 12 animals (Rattus norvegicus) also divided into three groups (control group [CG] - untreated burns; sulfadiazine group [SG] - burns were treated with silver sulfadiazine at 1%; laser group [LG] - burns were treated with photobiomodulation)...
January 1, 2017: Revista da Associação Médica Brasileira
https://www.readbyqxmd.com/read/28225761/amplified-stimulated-emission-in-upconversion-nanoparticles-for-super-resolution-nanoscopy
#20
Yujia Liu, Yiqing Lu, Xusan Yang, Xianlin Zheng, Shihui Wen, Fan Wang, Xavier Vidal, Jiangbo Zhao, Deming Liu, Zhiguang Zhou, Chenshuo Ma, Jiajia Zhou, James A Piper, Peng Xi, Dayong Jin
Lanthanide-doped glasses and crystals are attractive for laser applications because the metastable energy levels of the trivalent lanthanide ions facilitate the establishment of population inversion and amplified stimulated emission at relatively low pump power. At the nanometre scale, lanthanide-doped upconversion nanoparticles (UCNPs) can now be made with precisely controlled phase, dimension and doping level. When excited in the near-infrared, these UCNPs emit stable, bright visible luminescence at a variety of selectable wavelengths, with single-nanoparticle sensitivity, which makes them suitable for advanced luminescence microscopy applications...
February 22, 2017: Nature
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