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https://www.readbyqxmd.com/read/28231402/ex-vivo-visualization-of-human-ciliated-epithelium-and-quantitative-analysis-of-induced-flow-dynamics-by-using-optical-coherence-tomography
#1
Yuye Ling, Xinwen Yao, Ute A Gamm, Emilio Arteaga-Solis, Charles W Emala, Michael A Choma, Christine P Hendon
BACKGROUND AND OBJECTIVE: Cilia-driven mucociliary clearance is an important self-defense mechanism of great clinical importance in pulmonary research. Conventional light microscopy possesses the capability to visualize individual cilia and its beating pattern but lacks the throughput to assess the global ciliary activities and flow dynamics. Optical coherence tomography (OCT), which provides depth-resolved cross-sectional images, was recently introduced to this area. MATERIALS AND METHODS: Fourteen de-identified human tracheobronchial tissues are directly imaged by two OCT systems: one system centered at 1,300 nm with 6...
February 23, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28231400/evaluation-of-the-combined-use-of-narrow-band-imaging-and-high-speed-imaging-to-discriminate-laryngeal-lesions
#2
Veronika Volgger, Axelle Felicio, Jörg Lohscheller, Anna S Englhard, Hanan Al-Muzaini, Christian S Betz, Maria E Schuster
BACKGROUND AND OBJECTIVE: Laryngeal lesions are usually investigated by microlaryngoscopy, biopsy, and histopathology. This study aimed to evaluate the combined use of Narrow Band Imaging (NBI) and High-Speed Imaging (HSI) in the differentiation of glottic lesions in awake patients. STUDY DESIGN: Prospective diagnostic study. MATERIALS AND METHODS: Thirty-six awake patients with 41 glottic lesions were investigated with both NBI and HSI, and the suspected diagnoses were compared to the histopathological results of tissue biopsies taken during subsequent microlaryngoscopies...
February 23, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28231390/intraoperative-assessment-of-laryngeal-pathologies-with-optical-coherence-tomography-integrated-into-a-surgical-microscope
#3
Anna S Englhard, Tom Betz, Veronika Volgger, Eva Lankenau, Georg J Ledderose, Herbert Stepp, Christian Homann, Christian S Betz
OBJECTIVE: Endoscopic examination followed by tissue biopsy is the gold standard in the evaluation of lesions of the upper aerodigestive tract. However, it can be difficult to distinguish between healthy mucosa, dysplasia, and invasive carcinoma. Optical coherence tomography (OCT) is a non-invasive technique which acquires high-resolution, cross-sectional images of tissue in vivo. Integrated into a surgical microscope, it allows the intraoperative evaluation of lesions simultaneously with microscopic visualization...
February 23, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28225527/neuro-trauma-or-med-surg-intensive-care-unit-does-it-matter-where-multiple-injuries-patients-with-traumatic-brain-injury-are-admitted-secondary-analysis-of-the-american-association-for-the-surgery-of-trauma-multi-institutional-trials-committee-decompressive
#4
Sarah Lombardo, Thomas Scalea, Jason Sperry, Raul Coimbra, Gary Vercruysse, Toby Enniss, Gregory J Jurkovich, Raminder Nirula
INTRODUCTION: Patients with nontraumatic acute intracranial pathology benefit from neurointensivist care. Similarly, trauma patients with and without traumatic brain injury (TBI) fare better when treated by a dedicated trauma team. No study has yet evaluated the role of specialized neurocritical (NICU) and trauma intensive care units (TICU) in the management of TBI patients, and it remains unclear which TBI patients are best served in NICU, TICU, or general (Med/Surg) ICU. METHODS: This study is a secondary analysis of The American Association for the Surgery of Trauma Multi-Institutional Trials Committee (AAST-MITC) decompressive craniectomy study...
March 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/28220946/light-and-energy-based-therapeutics-for-genitourinary-syndrome-of-menopause-consensus-and-controversies
#5
Yona Tadir, Adrian Gaspar, Ahinoam Lev-Sagie, Macrene Alexiades, Red Alinsod, Alex Bader, Alberto Calligaro, Jorge A Elias, Marco Gambaciani, Jorge E Graviria, Cheryl B Iglesia, Ksenija Selih-Martinec, Patricia L Mwesigwa, Urska B Ogrinc, Stefano Salvatore, Paolo Scollo, Nicola Zerbinati, John Stuart Nelson
Gynecologist and plastic surgeons pioneered the application of lasers in medicine and surgery almost 5 decades ago, initially used to treat cervical and vaginal pathologies. Ever since, energy-based devices have been deployed to treat pelvic pathologies and improve fertility. Recent technological developments triggered an unprecedented wave of publications, assessing the efficacy of fractional laser, and radiofrequency on the vaginal wall in reversing natural aging processes. Studies have shown that a certain degree of thermal energy deposited on the vaginal wall stimulates proliferation of the glycogen-enriched epithelium, neovascularization, and collagen formation in the lamina propria, and improves natural lubrication and control of urination...
February 21, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28220508/quantitative-long-term-measurements-of-burns-in-a-rat-model-using-spatial-frequency-domain-imaging-sfdi-and-laser-speckle-imaging-lsi
#6
Adrien Ponticorvo, David M Burmeister, Rebecca Rowland, Melissa Baldado, Gordon T Kennedy, Rolf Saager, Nicole Bernal, Bernard Choi, Anthony J Durkin
BACKGROUND AND OJECTIVES: The current standard for diagnosis of burn severity and subsequent wound healing is through clinical examination, which is highly subjective. Several new technologies are shifting focus to burn care in an attempt to help quantify not only burn depth but also the progress of healing. While accurate early assessment of partial thickness burns is critical for dictating the course of treatment, the ability to quantitatively monitor wound status over time is critical for understanding treatment efficacy...
February 21, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28220505/fractional-microplasma-radiofrequency-technology-for-non-hypertrophic-post-burn-scars-in-asians-a-prospective-study-of-95-patients
#7
Shen Wang, Jing Mi, Qingfeng Li, Rui Jin, Jiying Dong
BACKGROUND: Laser and other energy devices are emerging, minimally invasive treatments for scars. Among the various techniques, fractional microplasma radiofrequency technology (FMRT) has proven to be an effective treatment option for various types of scars and skin conditions such as rhytids, striae distensae, and hyperpigmentation. OBJECTIVE: This prospective clinical trial was designed to evaluate the efficacy and safety of FMRT for treating non-hypertrophic post-burn scars in the Asian population...
February 20, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28185275/surface-markers-for-guiding-cylindrical-diffuser-fiber-insertion-in-interstitial-photodynamic-therapy-of-head-and-neck-cancer
#8
Emily Oakley, David A Bellnier, Alan Hutson, Brian Wrazen, Hassan Arshad, Harry Quon, Gal Shafirstein
BACKGROUND AND OBJECTIVES: Image-based treatment planning can be used to compute the delivered light dose during interstitial photodynamic therapy (I-PDT) of locally advanced head and neck squamous cell carcinoma (LA-HNSCC). The objectives of this work were to evaluate the use of surface fiducial markers and flexible adhesive grids in guiding interstitial placement of laser fibers, and to quantify the impact of discrepancies in fiber location on the expected light dose volume histograms (DVHs)...
February 10, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28181673/laser-induced-thermal-coagulation-enhances-skin-uptake-of-topically-applied-compounds
#9
C S Haak, J Hannibal, U Paasch, R R Anderson, M Haedersdal
BACKGROUND: Ablative fractional laser (AFL) generates microchannels in skin surrounded by a zone of thermally altered tissue, termed the coagulation zone (CZ). The thickness of CZ varies according to applied wavelength and laser settings. It is well-known that AFL channels facilitate uptake of topically applied compounds, but the importance of CZ is unknown. METHODS: Franz Cells were used to investigate skin uptake and permeation of fluorescent labeled polyethylene glycols (PEGs) with mean molecular weights (MW) of 350, 1,000, and 5,000 Da...
February 9, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28168812/optical-coherence-tomography-angiography-of-macular-telangiectasia-type-1-comparison-with-mild-diabetic-macular-edema
#10
Lei Mao, Si-Si Weng, Yuan-Yuan Gong, Su-Qin Yu
OBJECTIVE: The present study aimed to investigate the characteristics of macular telangiectasia type 1 (Mac tel type 1) using spectral-domain optical coherence tomography angiography (OCTA) and compare them with the characteristics of mild diabetic macular edema (DME), to provide a new objective method for quick clinical diagnosis and treatment. METHODS: A retrospective comparative analysis of 9 Mac tel type 1, 15 DME, and 15 normal eyes was performed using fluorescein angiography, spectral-domain optical coherence tomography, and OCTA...
February 7, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28141756/intensive-care-unit-acquired-weakness-implications-for-case-management
#11
Nina R Harvey, Marietta P Stanton
PURPOSE: The purpose of this case study is to provide a specific example of the disease trajectory for one patient's experience with intensive care unit-acquired weakness (ICUAW). This case study provides those in case management with an overview of some of the common signs and symptoms of ICUAW, as well as the possible prognosis and recovery from ICUAW. PRIMARY PRACTICE SETTING: The events in this case study take place in the acute care setting including the intensive care unit of a mid-sized health center, a general medical-surgical (med-surg) unit, and a long-term acute care facility...
March 2017: Professional Case Management
https://www.readbyqxmd.com/read/28134994/retrospective-analysis-of-the-treatment-of-melasma-lesions-exhibiting-increased-vascularity-with-the-595-nm-pulsed-dye-laser-combined-with-the-1927-nm-fractional-low-powered-diode-laser
#12
REVIEW
Elizabeth R C Geddes, Ashlyn B Stout, Paul M Friedman
BACKGROUND: Melasma presents a significant challenge to laser surgeons. Aggressive treatments often result in rebound melasma or post-inflammatory pigmentary alteration. Recent reports suggest melasma pathogenesis may have a vascular component. Spectrocolorimetry can detect subtle or sub-clinical telangiectatic erythema within melasma lesions. For certain patients identified by spectrocolorimetry, effective melasma treatment may include vascular-targeted therapy together with pigment-specific treatment modalities...
January 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28129441/automatic-identification-of-parathyroid-in-optical-coherence-tomography-images
#13
Fang Hou, Yang Yu, Yanmei Liang
BACKGROUND AND OBJECTIVE: The identification and preservation of parathyroid is a major problem in thyroid surgery. In order to solve this problem, optical coherence tomography was involved as a real-time, non-invasive high-resolution imaging technique. This study demonstrated an effective and fast method to distinguish parathyroid tissue from thyroid, lymph node, and adipose tissue in their ex vivo optical coherence tomography (OCT) images automatically. METHODS: OCT images were obtained from parathyroid, thyroid, lymph node, and adipose tissue, respectively...
January 27, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28129436/improving-the-strength-of-sutureless-laser-assisted-vessel-repair-using-preloaded-longitudinal-compression-on-tissue-edge
#14
Ryu Nakadate, Shigeru Omori, Tetsuo Ikeda, Tomohiko Akahoshi, Susumu Oguri, Jumpei Arata, Shinya Onogi, Makoto Hashizume
BACKGROUND AND OBJECTIVE: Little is known about the approximation of coapted edges in sutureless laser-assisted vessel welding. Tissue shrinkage by laser irradiation may cause coapted edges to separate, reducing strength of welding. This may be avoided by preloaded longitudinal compression on the tissue edges to be welded. This study compared welding strength with and without preloaded compression in ex vivo animal experiments. MATERIALS AND METHODS: This study evaluated 24 samples of harvested porcine carotid arteries, each having a length of 3 cm and an inner diameter of 1...
January 27, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28117496/early-use-of-co2-lasers-and-silicone-gel-on-surgical-scars-prospective-study
#15
Luiz Ronaldo Alberti, Eduardo Faria Vicari, Roselaine De Souza Jardim Vicari, Andy Petroianu
INTRODUCTION: Some publications have shown good aesthetic results for scars through the early application of fractional CO2 lasers on elective surgery scars. The aim of this randomized, double-blinded clinical trial was to compare the aesthetic quality of the scar from a group of patients submitted to super-pulsed fractional CO2 laser applications (10,600 nm fractional CO2 , set at a density of 20% and an energy of 10 mJ, a scanner of 03 × 03 mm, and a pulse repetition time of 0...
January 24, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28117489/rejuvenation-of-the-male-scalp-using-1-927%C3%A2-nm-non-ablative-fractional-thulium-fiber-laser
#16
Monica Boen, Monique J Vanaman Wilson, Mitchel P Goldman, Douglas C Wu
OBJECTIVE: The male scalp undergoes extensive photodamage due to a high prevalence of androgenic alopecia and exposure to ultraviolet radiation. This photodamage presents as solar lentigines, fine rhytides, and keratosis, and can prematurely age a patient. In this study, we demonstrate the safety and efficacy of the fractionated 1,927 nm thulium fiber laser using high density and high energy settings to achieve rejuvenation of the male scalp after a single treatment session. METHODS: Four male patients with Fitzpatrick skin types II-III and extensive photodamage on the scalp underwent one treatment with the fractional non-ablative 1,927 nm thulium fiber laser...
January 24, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28115033/development-of-an-evacuation-tool-to-facilitate-disaster-preparedness-use-in-a-planned-evacuation-to-support-a-hospital-move
#17
Ranna A Rozenfeld, Sally L Reynolds, Sherri Ewing, Mary Margaret Crulcich, Michelle Stephenson
OBJECTIVES: Our institution relocated to a new facility 3.5 miles from our original location in Chicago on June 9, 2012. We describe the tools we developed to prepare, execute, and manage our evacuation and relocation. METHODS: Tools developed for the planned evacuation included the following: level of acuity and team composition classification, patient departure checklist, evacuation handoff tool, and a patient tracking system within the electronic health record...
January 24, 2017: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/28103642/subcutaneous-adipose-tissue-response-to-a-non-invasive-hyperthermic-treatment-using-a-1-060%C3%A2-nm-laser
#18
John W Decorato, Bo Chen, Rafael Sierra
BACKGROUND: We postulated that a hyperthermic treatment using a 1,060 nm laser can cause a controlled adipocyte injury resulting in non-invasive fat reduction. This three-part study identified treatment parameters for a safe and tolerable treatment, demonstrated short- and long-term tissue response, and assessed the potential of this treatment for non-invasive fat reduction. METHODS: In vivo temperature measurements were conducted prior to abdominoplasty via a thermal camera (for surface readings) and thermocouple needle (for subcutaneous readings)...
January 19, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28103628/treatment-of-a-vulvar-paget-s-disease-by-photodynamic-therapy-with-a-new-light-emitting-fabric-based-device
#19
Claire Vicentini, Olivier Carpentier, Fabienne Lecomte, Elise Thecua, Laurent Mortier, Serge R Mordon
INTRODUCTION: The non-invasive vulvar Paget's disease is an intra-epidermal carcinoma with glandular characteristics. It appears like an erythematous plaque. The main symptoms are pruritus and pain. The standard treatment is surgical excision in depth. This treatment is complicated with a severe morbidity and photodynamic therapy can be an alternative choice. However, the pain experienced during the photodynamic treatment of vulvar lesion is intense and leads to a premature interruption of the treatment...
January 19, 2017: Lasers in Surgery and Medicine
https://www.readbyqxmd.com/read/28075022/the-mechanistic-basis-for-photobiomodulation-therapy-of-neuropathic-pain-by-near-infrared-laser-light
#20
Vanessa Milanesi Holanda, Maria Cristina Chavantes, Xingjia Wu, Juanita J Anders
BACKGROUND AND OBJECTIVE: Various irradiances have been reported to be beneficial for the treatment of neuropathic pain with near infrared light. However, the mechanistic basis for the beneficial outcomes may vary based on the level of irradiance or fluence rate used. Using in vivo and in vitro experimental models, this study determined the mechanistic basis of photobiomodulation therapy (PBMT) for the treatment of neuropathic pain using a high irradiance. STUDY DESIGN/MATERIALS AND METHODS: In vitro experiments: Cultured, rat DRG were randomly assigned to control or laser treatment (LT) groups with different irradiation times (2, 5, 30, 60, or 120 seconds)...
January 11, 2017: Lasers in Surgery and Medicine
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