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https://www.readbyqxmd.com/read/28989074/safety-of-active-rehabilitation-for-persistent-symptoms-after-pediatric-sport-related-concussion-a-randomized-controlled-trial
#1
Catherine Chan, Grant L Iverson, Jacqueline Purtzki, Kathy Wong, Vivian Kwan, Isabelle Gagnon, Noah D Silverberg
OBJECTIVE: To examine the safety and tolerability of an active rehabilitation program for adolescents who are slow to recover from a sport-related concussion. A secondary objective was to estimate the treatment effect for this intervention. DESIGN: Single-site parallel open-label randomized controlled trial (RCT) comparing treatment as usual (TAU) to TAU plus active rehabilitation. SETTING: Outpatient concussion clinic. PARTICIPANTS: Adolescents aged 12-18 with postconcussion symptoms lasting >1 month after a sports-related concussion...
October 5, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28986325/an-emotional-go-no-go-fmri-study-in-adolescents-with-depressive-symptoms-following-concussion
#2
Rachelle A Ho, Geoffrey B Hall, Michael D Noseworthy, Carol DeMatteo
BACKGROUND: Following concussion, adolescents may experience both poor inhibitory control and increased depressive symptoms. fMRI research suggests a physiological difference between patients with clinical depression and patients with depressive symptoms after concussion. The scarcity of information surrounding depression following concussion in youth makes it difficult to identify patients at risk of depression after injury. This is the first study to examine neural activity patterns in adolescents with post-concussive depressive symptoms...
October 3, 2017: International Journal of Psychophysiology
https://www.readbyqxmd.com/read/28980825/does-the-fear-avoidance-model-explain-persistent-symptoms-after-traumatic-brain-injury
#3
Melloney L M Wijenberg, Sven Z Stapert, Jeanine A Verbunt, Jennie L Ponsford, Caroline M Van Heugten
BACKGROUND: A minority of patients with mild traumatic brain injury (mTBI) experience a persistent symptom complex also known as post-concussion syndrome. Explanations for this syndrome are still lacking. OBJECTIVE: To investigate if the fear avoidance model, including catastrophizing thoughts and fear avoidance behaviour, poses a possible biopsychosocial explanation for lingering symptoms and delay in recovery after traumatic brain injury (TBI) with special focus on mTBI...
October 5, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28979609/examining-microstructural-white-matter-in-active-duty-soldiers-with-a-history-of-mild-traumatic-brain-injury-and-traumatic-stress
#4
Michael N Dretsch, Rael T Lange, Jeffery S Katz, Adam Goodman, Thomas A Daniel, Gopikrishna Deshpande, Thomas S Denney, Grant L Iverson, Jennifer L Robinson
BACKGROUND: There is a high comorbidity of posttraumatic stress (PTS) and mild traumatic brain injury (mTBI), with largely overlapping symptomatology, in military service members. OBJECTIVE: To examine white matter integrity associated with PTS and mTBI as assessed using diffusion tensor imaging (DTI). METHOD: Seventy-four active-duty U.S. soldiers with PTS (n = 16) and PTS with co-morbid history of mTBI (PTS/mTBI; n = 28) were compared to a military control group (n = 30)...
2017: Open Neuroimaging Journal
https://www.readbyqxmd.com/read/28969486/prognostic-value-of-s-100%C3%A3-protein-for-prediction-of-post-concussion-symptoms-following-a-mild-traumatic-brain-injury-systematic-review-and-meta-analysis
#5
Eric Mercier, Pier-Alexandre Tardif, Peter Cameron, Brice Lionel Batomen Kuimi, Marcel Émond, Lynne Moore, Biswadev Mitra, Jérôme Frenette, Elaine de Guise, Marie-Christine Ouellet, Martine Bordeleau, Natalie Le Sage
This systematic review and meta-analysis aimed to determine the prognostic value of S-100β protein to identify patients with post-concussion symptoms following a mild traumatic brain injury (mTBI). A search strategy was submitted to seven databases from their inception to October 2016. Individual patient data were requested. Cohort studies evaluating the association between S-100β protein level and post-concussion symptoms assessed at least seven days after the mTBI were considered. Outcomes were dichotomised as persistent (>= 3 months) or early (>= 7 days < 3 months)...
October 2, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28963310/characteristics-of-patients-included-and-enrolled-in-studies-on-the-prognostic-value-of-serum-biomarkers-for-prediction-of-postconcussion-symptoms-following-a-mild-traumatic-brain-injury-a-systematic-review
#6
Eric Mercier, Pier-Alexandre Tardif, Marcel Emond, Marie-Christine Ouellet, Élaine de Guise, Biswadev Mitra, Peter Cameron, Natalie Le Sage
OBJECTIVE: Mild traumatic brain injury (mTBI) has been insufficiently researched, and its definition remains elusive. Investigators are confronted by heterogeneity in patients, mechanism of injury and outcomes. Findings are thus often limited in generalisability and clinical application. Serum protein biomarkers are increasingly assessed to enhance prognostication of outcomes, but their translation into clinical practice has yet to be achieved. A systematic review was performed to describe the adult populations included and enrolled in studies that evaluated the prognostic value of protein biomarkers to predict postconcussion symptoms following an mTBI...
September 27, 2017: BMJ Open
https://www.readbyqxmd.com/read/28952858/sub-symptomatic-aerobic-exercise-for-patients-with-post-concussion-syndrome-a-critically-appraised-topic
#7
Katrina G Ritter, Matthew J Hussey, Tamara C Valovich McLeod
Clinical Scenario: Patients who experience prolonged concussion symptoms can be diagnosed with Post-Concussion Syndrome (PCS) when those symptoms persist past 4 weeks. Aerobic exercise protocols have been shown to be effective in improving physical and mental aspects of health. Emerging research suggests that aerobic exercise maybe useful as a treatment for PCS, where exercise allows patients to feel less isolated and more active during the recovery process. CLINICAL QUESTION: Is aerobic exercise more beneficial in reducing symptoms than current standard care in patients with prolonged symptoms or PCS lasting longer than 4 weeks? Summary of Key Findings: After a thorough literature search, 4 studies were selected relevant to the clinical question...
September 27, 2017: Journal of Sport Rehabilitation
https://www.readbyqxmd.com/read/28939003/factors-associated-with-post-concussion-syndrome-in-high-school-student-athletes
#8
Zachary Y Kerr, Scott L Zuckerman, Erin W Wasserman, Christina B Vander Vegt, Aaron Yengo-Kahn, Thomas A Buckley, Gary S Solomon, Allen K Sills, Thomas P Dompier
OBJECTIVES: To identify factors associated with post-concussion syndrome (PCS) among a national sample of high school student-athletes from the 2011/12-2013/14 academic years. DESIGN: Ambispective cohort study from sports injury surveillance data. METHODS: Sport-related concussion data originated from the National Athletic Treatment, Injury and Outcomes Network (NATION) surveillance program, consisting of 27 sports from a convenience sample of 196 high schools across 26 states...
September 14, 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28927553/self-report-balance-status-is-not-reliable-post-concussion
#9
EDITORIAL
Gordon S Waddington
No abstract text is available yet for this article.
November 2017: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/28926482/is-there-an-optimal-time-to-initiate-an-active-rehabilitation-protocol-for-concussion-management-in-children-a-case-series
#10
Danielle M Dobney, Lisa Grilli, Helen Kocilowicz, Christine Beaulieu, Meghan Straub, Debbie Friedman, Isabelle J Gagnon
OBJECTIVE: To estimate the time frame during which initiating an active rehabilitation intervention (aerobic exercise, balance, and sport specific skills) after concussion contributed to improvement in symptoms at follow-up in children and adolescents who are slow to recover (symptoms persisting beyond 2 weeks) from concussion. SETTING: Concussion clinic at a tertiary care pediatric teaching hospital. PARTICIPANTS: A total of 677 children and adolescents with concussion aged 7 to 18 years...
September 18, 2017: Journal of Head Trauma Rehabilitation
https://www.readbyqxmd.com/read/28925734/a-pilot-treatment-study-for-mild-traumatic-brain-injury-neuroimaging-changes-detected-by-meg-after-low-intensity-pulse-based-transcranial-electrical-stimulation
#11
Ming-Xiong Huang, Ashley Robb Swan, Annemarie Angeles Quinto, Scott Matthews, Deborah L Harrington, Sharon Nichols, Barry J Bruder, Corey C Snook, Charles W Huang, Dewleen G Baker, Roland R Lee
BACKGROUND: Mild traumatic brain injury (mTBI) is a leading cause of sustained impairments in military service members, Veterans, and civilians. However, few treatments are available for mTBI, partially because the mechanism of persistent mTBI deficits is not fully understood. METHODS: We used magnetoencephalography (MEG) to investigate neuronal changes in individuals with mTBI following a passive neurofeedback-based treatment programme called IASIS. This programme involved applying low-intensity pulses using transcranial electrical stimulation (LIP-tES) with electroencephalography monitoring...
September 19, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28918391/genetic-polymorphisms-associated-with-the-risk-of-concussion-in-1056-college-athletes-a-multicentre-prospective-cohort-study
#12
Thomas Roland Terrell, Ruth Abramson, Jeffery T Barth, Ellen Bennett, Robert C Cantu, Richard Sloane, Daniel T Laskowitz, David M Erlanger, Douglas McKeag, Gregory Nichols, Verle Valentine, Leslie Galloway
BACKGROUND/AIM: To evaluate the association of genetic polymorphisms APOE, APOE G-219T promoter, microtubule associated protein(MAPT)/tau exon 6 Ser(53)Pro, MAPT/tau Hist(47)Tyr, IL-6572 G/C and IL-6R(Asp)358(Ala) with the risk of concussion in college athletes. METHODS: A 23-centre prospective cohort study of 1056 college athletes with genotyping was completed between August 2003 and December 2012. All athletes completed baseline medical and concussion questionnaires, and post-concussion data were collected for athletes with a documented concussion...
September 16, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28895491/preliminary-validation-of-the-whodas-2-0-for-mild-traumatic-brain-injury
#13
Deborah Snell, Grant L Iverson, William Panenka, Noah D Silverberg
The purpose of this study is to examine the reliability, factor structure, and validity of the World Health Organization Disability Assessment Schedule (WHODAS 2.0 12-item version) in a sample of patients who were slow to recover from a mild traumatic brain injury (MTBI). Participants were 79 adults with MTBI recruited from one of four specialty outpatient clinics in Vancouver, Canada. The WHODAS 2.0 12-item version is a disease-non-specific measure of disability representing six International Classification of Disability, Functioning, and Health activity and participation domains including cognition, mobility, self-care, interpersonal functioning, life activities, and participation...
September 12, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28895490/the-association-between-dual-task-gait-after-concussion-and-prolonged-symptom-duration
#14
David Robert Howell, Anna Brilliant, Brant Berkstresser, Francis Wang, Joana Fraser, William Meehan
Quantitative gait measurements can identify persistent post-concussion impairments. However, their prognostic utility after injury to identify the likelihood of prolonged concussion symptoms remains unknown. Our objective was to examine if dual-task gait performance measures are independently associated with persistent (> 28 days) concussion symptoms among a sample of athletes. Sixty individuals diagnosed with a sport-related concussion were assessed within 10 days of their injury. Each participant completed a post-concussion symptom scale, injury history questionnaire, and a single/dual-task gait examination...
September 12, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28889832/intra-individual-cognitive-variability-an-examination-of-anam4-tbi-mil-simple-reaction-time-data-from-service-members-with-and-without-mild-traumatic-brain-injury
#15
Wesley R Cole, Emma Gregory, Jacques P Arrieux, F Jay Haran
OBJECTIVES: The Automated Neuropsychological Assessment Metrics 4 TBI-MIL (ANAM4) is a computerized cognitive test often used in post-concussion assessments with U.S. service members (SMs). Existing evidence, however, remains mixed regarding ANAM4's ability to identify cognitive issues following mild traumatic brain injury (mTBI). Studies typically examine ANAM4 by comparing mean scores to baseline or normative scores. A more fine-grained approach involves examining inconsistency within an individual's performance...
September 11, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/28882543/longitudinal-study-of-a-nogo-p3-event-related-potential-component-following-mild-traumatic-brain-injury-in-adults
#16
Gian Candrian, Andreas Müller, Patrizia Dall'Acqua, Kyveli Kompatsiari, Gian-Marco Baschera, Ladislav Mica, Hans-Peter Simmen, Richard Glaab, Javier Fandino, Markus Schwendinger, Christoph Meier, Erika Jasmin Ulbrich, Sönke Johannes
BACKGROUND: Event-related potentials have repeatedly revealed electrophysiological markers of cognitive dysfunction associated with Mild Traumatic Brain Injury (MTBI) and may represent a sensitive tool to guide cognitive rehabilitative interventions. We previously found patients with symptomatic MTBI characterized by smaller P300 (or P3) wave amplitudes in a NoGo-P3 subcomponent in the acute phase of the injury. The goal of this longitudinal study was to investigate whether this early NoGo-P3 subcomponent differs over time in symptomatic MTBI patients and healthy controls...
September 4, 2017: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28876149/acute-post-concussive-symptoms-in-young-children
#17
Coco Bernard, Audrey McKinlay, David Krieser, Renee Testa, And Jennie Ponsford
OBJECTIVES: Despite peaks of mild traumatic brain injury (mTBI) incidence in young children, few studies have examined the nature of post-concussive symptoms (PCSs) in children under the age of eight, whilst controlling for pre-injury symptoms and effects of trauma. The current study aimed to identify which PCSs differentiate children with mTBI from trauma controls early post-injury, and whether these differed among preschool and school-aged children. METHODS: The sample comprised 101 children aged 2-12 presenting to an emergency department, with concussion or other minor bodily injury (control)...
September 6, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28874926/craniosacral-therapy-and-visceral-manipulation-a-new-treatment-intervention-for-concussion-recovery
#18
Gail Wetzler, Melinda Roland, Sally Fryer-Dietz, Dee Dettmann-Ahern
Background: Military service members and veterans face health issues related to traumatic brain injury (TBI), especially during combat, use of heavy equipment, and exposures to environmental hazards and explosives. There were 400,000 TBIs reported in deployed U.S. troops in 2012. Athletes are also subject to TBI. Studies have indicated that some manual therapies could be helpful for treating patients who have post-concussive syndrome. Objective: This case series report describes the effects of CranioSacral Therapy (CST), Visceral Manipulation (VM), and Neural Manipulation (NM) modalities for treating patients who have post-concussion syndrome...
August 1, 2017: Medical Acupuncture
https://www.readbyqxmd.com/read/28872365/recovery-progression-and-symptom-resolution-in-sport-related-mild-traumatic-brain-injury
#19
Ensie Abbassi, Bess Sirmon-Taylor
OBJECTIVE: To characterize the recovery progression of a group of athletes who participated in a concussion management program based on (1) group analysis and (2) individual analysis. SETTING: Concussion management clinic. PARTICIPANTS: Thirty athletes (22 males, 8 females; baseline age = 16.23 ± 2.40 years) who had undergone four assessments: one baseline and three post-injury assessments at 3, 8, 15 days post-injury. DESIGN: Retrospective clinical...
September 5, 2017: Brain Injury: [BI]
https://www.readbyqxmd.com/read/28872344/quality-of-return-to-work-in-patients-with-mild-traumatic-brain-injury-a-prospective-investigation-of-associations-among-post-concussion-symptoms-neuropsychological-functions-working-status-and-stability
#20
Shao-Ying Chu, Yi-Hsin Tsai, Sheng-Huang Xiao, Sheng-Jean Huang, Chi-Cheng Yang
PRIMARY OBJECTIVE: Although 'return to work' (RTW) has been always emphasized for patients with mild traumatic brain injury (MTBI), methodological drawbacks weakened its representativeness. This study thus aims to evaluate the 'work quality' (WQ) which originated from 'working status' and 'working stability' simultaneously, and to further explore the associations among post-concussion symptoms (PCS), neuropsychological functions and WQ. METHODS AND PROCEDURES: A total of 179 participants, which included 132 patients with MTBI and 47 healthy participants, were prospectively recruited...
September 5, 2017: Brain Injury: [BI]
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