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https://www.readbyqxmd.com/read/28743080/the-role-of-hexon-in-egg-drop-syndrome-virus-edsv-inducing-apoptosis-in-duck-embryo-fibroblast-cells
#1
Xuefeng Qi, Jiamin Xu, Zugui Wang, Xueping Wang, Jingyu Wang
Although extensive efforts have been made to understand adenovirus infection in human cells, little is known for egg drop syndrome virus (EDSV) infection in the avian-derived cells. In this study, the effects of EDSV infection as well as the possible role hexon protein, the main building block of the EDSV capsid, on apoptosis induction in duck embryo fibroblast (DEF) cells was examined. Flow cytometry analysis and TUNEL assay revealed that EDSV infection induced significant apoptosis in DEF cells compared with mock infected cells...
July 17, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28743065/enantiomerization-and-stereoselectivity-in-bioaccumulation-of-furalaxyl-in-tenebrio-molitor-larvae
#2
Jing Yin, Yongxin Gao, Feilong Zhu, Weiyu Hao, Qi Xu, Huili Wang, Baoyuan Guo
Furalaxyl is a chiral pesticide and widely used in modern agriculture as racemate mixture. The enantiomerization and enantioselecive bioaccumulation by a single dose of furalaxyl to Tenebrio molitor larvae under laboratory conditions were studied using a high-performance liquid chromatography tandem mass spectroscopy method based on a ChiralPAK IC column. Our results showed that a significant enantiomerization (interconversion between R-enantiomer and S-enantiomer) was observed in Tenebrio molitor larvae under R- or S-furalaxyl exposure...
July 22, 2017: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/28742761/preparation-and-assessment-of-an-individualized-navigation-template-for-lower-cervical-anterior-transpedicular-screw-insertion-using-a-three-dimensional-printing-technique
#3
FengNing Li, Xuan Huang, Kun Wang, BeiEr Luo, Fan Zhang, Zhi Chen, Quan Li, YongJin Zhang, Ke Qi, ChengChun Jin, WangShenJie Chen, CangLong Hou, HongXing Shen
STUDY DESIGN: Prospective trial. OBJECTIVE: To establish an individualized navigation template for safe and accurate insertion of lower cervical anterior transpedicular screw (ATPS) based on a three-dimensional (3D) printing technique. SUMMARY OF BACKGROUND DATA: Conventional screw insertion manually under fluoroscopy easily leading to deviation of ATPS screw channel, cervical instrumentation procedures demand the need for a precise technique for screw placement...
July 24, 2017: Spine
https://www.readbyqxmd.com/read/28742645/quality-improvement-in-management-of-acute-coronary-syndrome-continuing-medical-education-and-peer-coaching-improve-antiplatelet-medication-adherence-and-reduce-hospital-readmissions
#4
Amy Larkin, Michael LaCouture, Kathleen Geissel, Peri Barr, Eric R Bates, Christopher P Cannon, Deepak L Bhatt
BACKGROUND: Reducing hospital readmissions and improving patient adherence to antiplatelet medications after an acute coronary syndrome (ACS) event are important goals for improving patient health and decreasing healthcare costs. Nearly half of patients will have a secondary event within 1 year of the initial ACS event. Quality improvement (QI) initiatives that include continuing medical education and peer coaching may improve physician practice patterns and, therefore, patient outcomes...
September 2017: Critical Pathways in Cardiology
https://www.readbyqxmd.com/read/28742157/angiotensin-ii-system-in-the-nucleus-tractus-solitarii-contributes-to-autonomic-dysreflexia-in-rats-with-spinal-cord-injury
#5
Kai Wang, Shaoxia Duan, Xueping Wen, Weizhong Wang, Shangping Fang, Dunyi Qi, Xiang Huan, Liwei Wang, Zhenzhou He
BACKGROUND: Autonomic dysreflexia (AD) is a potentially life-threating complication after spinal cord injury (SCI), characterized by episodic hypertension induced by colon or bladder distension. The objective of this study was to determine the role of impaired baroreflex regulation by the nucleus tractus solitarii(NTS) in the occurrence of AD in a rat model. METHODS: T4 spinal cord transection animal model was used in this study, which included 40 Male rats Colorectal distension (CD) was performed to assess AD and compare the changes of BP, HR, and BRS, six weeks after operation...
2017: PloS One
https://www.readbyqxmd.com/read/28742153/reconstructing-the-regulatory-circuit-of-cell-fate-determination-in-yeast-mating-response
#6
Bin Shao, Haiyu Yuan, Rongfei Zhang, Xuan Wang, Shuwen Zhang, Qi Ouyang, Nan Hao, Chunxiong Luo
Massive technological advances enabled high-throughput measurements of proteomic changes in biological processes. However, retrieving biological insights from large-scale protein dynamics data remains a challenging task. Here we used the mating differentiation in yeast Saccharomyces cerevisiae as a model and developed integrated experimental and computational approaches to analyze the proteomic dynamics during the process of cell fate determination. When exposed to a high dose of mating pheromone, the yeast cell undergoes growth arrest and forms a shmoo-like morphology; however, at intermediate doses, chemotropic elongated growth is initialized...
July 24, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28742120/virus-induced-asthma-attack-the-importance-of-allergic-inflammation-in-response-to-viral-antigen-in-an-animal-model-of-asthma
#7
Christopher Skappak, Ramses Ilarraza, Ying-Qi Wu, Matthew G Drake, Darryl J Adamko
Asthma exacerbation can be a life-threatening condition, and is most often triggered by common respiratory viruses. Poor asthma control and worsening of respiratory function is associated with increased airway inflammation, including eosinophilia. Prevention of asthma exacerbation relies on treatment with corticosteroids, which preferentially inhibit allergic inflammation like eosinophils. Human studies demonstrate that inactivated virus can trigger eosinophil activation in vitro through antigen presentation and memory CD4+ lymphocytes...
2017: PloS One
https://www.readbyqxmd.com/read/28741997/paracoccus-hibiscisoli-sp-nov-isolated-from-the-rhizosphere-of-mugunghwa-hibiscus-syriacus
#8
Pei Lin, Zheng-Fei Yan, Kyung-Hwa Won, Jung-Eun Yang, Chang-Tian Li, MooChang Kook, Qi-Jun Wang, Tae-Hoo Yi
A Gram-reaction-negative, aerobic, non-motile, short-rod-shaped bacterium (THG-T2.31T) was isolated from the rhizosphere of Mugunghwa (Hibiscus syriacus). Growth occurred at 10-35 °C (optimum 28 °C), at pH 5.0-8.0 (optimum pH 7.0) and with 0-4.0 % NaCl (optimum 1.0 %). Based on 16S rRNA gene sequence analysis, the nearest phylogenetic neighbours of strain THG-T2.31T were identified as Paracoccus marcusii DSM 11574T (98.4 %), Paracoccus haeundaensis BC74171T (98.3 %), Paracoccus carotinifaciens E-396T (98...
July 26, 2017: International Journal of Systematic and Evolutionary Microbiology
https://www.readbyqxmd.com/read/28741854/toward-activity-origin-of-electrocatalytic-hydrogen-evolution-reaction-on-carbon-rich-crystalline-coordination-polymers
#9
Lihuan Wang, Diana C Tranca, Jian Zhang, Yanpeng Qi, Stavroula Sfaelou, Tao Zhang, Renhao Dong, Xiaodong Zhuang, Zhikun Zheng, Gotthard Seifert
The fundamental understanding of electrocatalytic active sites for hydrogen evolution reaction (HER) is significantly important for the development of metal complex involved carbon electrocatalysts with low kinetic barrier. Here, the MSx Ny (M = Fe, Co, and Ni, x/y are 2/2, 0/4, and 4/0, respectively) active centers are immobilized into ladder-type, highly crystalline coordination polymers as model carbon-rich electrocatalysts for H2 generation in acid solution. The electrocatalytic HER tests reveal that the coordination of metal, sulfur, and nitrogen synergistically facilitates the hydrogen ad-/desorption on MSx Ny catalysts, leading to enhanced HER kinetics...
July 25, 2017: Small
https://www.readbyqxmd.com/read/28741748/porous-organic-polymers-for-post-combustion-carbon-capture
#10
REVIEW
Lanfang Zou, Yujia Sun, Sai Che, Xinyu Yang, Xuan Wang, Matheiu Bosch, Qi Wang, Hao Li, Mallory Smith, Shuai Yuan, Zachary Perry, Hong-Cai Zhou
One of the most pressing environmental concerns of our age is the escalating level of atmospheric CO2 . Intensive efforts have been made to investigate advanced porous materials, especially porous organic polymers (POPs), as one type of the most promising candidates for carbon capture due to their extremely high porosity, structural diversity, and physicochemical stability. This review provides a critical and in-depth analysis of recent POP research as it pertains to carbon capture. The definitions and terminologies commonly used to evaluate the performance of POPs for carbon capture, including CO2 capacity, enthalpy, selectivity, and regeneration strategies, are summarized...
July 25, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28741712/a-series-of-linear-feiii2feii-complexes-with-paramagnetic-building-block-modified-spin-crossover-behaviors
#11
Ji-Xiang Hu, Yin-Shan Meng, Liang Zhao, Hai-Lang Zhu, Lei Liu, Qiang Liu, Cheng-Qi Jiao, Tao Liu
Tuning the spin crossover (SCO) behavior through paramagnetic building blocks with different steric hindrance is of great interest for the synergy between SCO and magnetic interactions. Here we modified the steric effect of specified FeIII building blocks from large steric hindrance Tp* (hydridotris(3,5-dimethylpyrazol-1-yl)borate) analogue to small steric hindrance Tp (hydrotris(pyrazolyl)borate) derivative, the FeII SCO unit and FeIII paramagnetic ions were incorporated into three well-isolated trinuclear complexes featuring thermally- and light-induced SCO properties...
July 25, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28741200/short-and-long-term-outcomes-in-malnourished-patients-after-laparoscopic-or-open-radical-gastrectomy
#12
Hua-Long Zheng, Jun Lu, Chao-Hui Zheng, Ping Li, Jian-Wei Xie, Jia-Bin Wang, Jian-Xian Lin, Qi-Yue Chen, Mi Lin, Ru-Hong Tu, Chang-Ming Huang
OBJECTIVE: The aim of this study was to compare the short- and long-term outcomes of malnourished gastric cancer patients who underwent laparoscopic or open radical gastrectomy. BACKGROUND: Preoperative malnutrition is an independent risk factor for postoperative mortality and morbidity in major gastrointestinal surgery. However, whether laparoscopic surgery can improve the short- and long-term outcomes of malnourished gastric cancer patients has not been determined...
July 24, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28741107/development-and-optimization-of-a-novel-sample-preparation-method-cored-on-functionalized-nanofibers-mat-solid-phase-extraction-for-the-simultaneous-efficient-extraction-of-illegal-anionic-and-cationic-dyes-in-foods
#13
Feifei Qi, Ningge Jian, Liangliang Qian, Weixin Cao, Qian Xu, Jian Li
A simple and efficient three-step sample preparation method was developed and optimized for the simultaneous analysis of illegal anionic and cationic dyes (acid orange 7, metanil yellow, auramine-O, and chrysoidine) in food samples. A novel solid-phase extraction (SPE) procedure based on nanofibers mat (NFsM) was proposed after solvent extraction and freeze-salting out purification. The preferred SPE sorbent was selected from five functionalized NFsMs by orthogonal experimental design, and the optimization of SPE parameters was achieved through response surface methodology (RSM) based on the Box-Behnken design (BBD)...
July 24, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28741094/systolic-function-of-right-ventricular-outflow-tract-is-a-better-predictor-to-exercise-performance-after-pulmonary-valve-replacement-in-tetralogy-of-fallot
#14
Jianhua Li, Shuhua Luo, Fei Liu, Qi An
Debate on the proper timing of pulmonary valve replacement (PVR) after repair of tetralogy of Fallot is still continuing. We aim to clarify how the different components of right ventricle (RV) changed with relieved volume overload in the remodeling process after pulmonary valve replacement and gain a clear idea of the relationship between different right ventricle components function and exercise capacity after PVR in these patients. The medical records and results of cardiac magnetic resonance imaging and cardiopulmonary exercise testing of 25 consecutive eligible patients were reviewed...
July 24, 2017: Pediatric Cardiology
https://www.readbyqxmd.com/read/28741062/ethanol-extract-of-ilex-hainanensis-merr-exhibits-anti-melanoma-activity-by-induction-of-g1-s-cell-cycle-arrest-and-apoptosis
#15
Ya-Qi Zhang, Hao Yang, Wei-Dong Sun, Juan Wang, Bao-Yuan Zhang, Yan-Jun Shen, Min-Qiang Yin, Yun-Xing Liu, Chang Liu, Yun Sun
OBJECTIVE: To evaluate anti-melanoma effect of ethanol extract of Ilex hainanensis Merr. (IME) and elucidate its underlying mechanism. METHODS: Thirty-six tumor-bearing mice were randomized into 6 groups (n=6) as follows: model group, IME 25, 50, 100, and 200 mg/kg groups and dacarbazine (DTIC) 70 mg/kg group. The mice in the IME treatment groups were intragastrically administered with IME 25, 50, 100 or 200 mg/kg per day, respectively. The mice in the DTIC group were intraperitoneally injected with DTIC 70 mg/kg every 2 days...
July 25, 2017: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/28740987/rational-synthesis-of-hierarchical-magnetic-mesoporous-silica-microspheres-with-tunable-mesochannels-for-enhanced-enzyme-immobilization
#16
Dapeng Li, Renxing Yi, Jiangwei Tian, Jinhua Li, Boyang Yu, Jin Qi
Hierarchical magnetic mesoporous silica microspheres (MMSMs) with a core-shell structure have been fabricated through an improved water/oil biphase synthesis strategy. We firstly reported that the mesopore size can be readily tuned from 6.1 to 11.4 nm by the synergistic effect of surfactant concentration and an amphiphilic agent, thus holding a bright future in many possible applications.
July 25, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28740748/a-highly-pathogenic-porcine-reproductive-and-respiratory-syndrome-virus-candidate-vaccine-based-on-japanese-encephalitis-virus-replicon-system
#17
Pingsheng Hu, Xiaoming Chen, Lihong Huang, Shukai Liu, Fuyu Zang, Jinchao Xing, Youyue Zhang, Jiaqi Liang, Guihong Zhang, Ming Liao, Wenbao Qi
In the swine industry, porcine reproductive and respiratory syndrome (PRRS) is a highly contagious disease which causes heavy economic losses worldwide. Effective prevention and disease control is an important issue. In this study, we described the construction of a Japanese encephalitis virus (JEV) DNA-based replicon with a cytomegalovirus (CMV) promoter based on the genome of Japanese encephalitis live vaccine virus SA14-14-2, which is capable of offering a potentially novel way to develop and produce vaccines against a major pathogen of global health...
2017: PeerJ
https://www.readbyqxmd.com/read/28740561/edta-assisted-phase-conversion-synthesis-of-gd0-95re0-05-po4-nanowires-re-eu-tb-and-investigation-of-photoluminescence
#18
Zhihao Wang, Ji-Guang Li, Qi Zhu, Zhengrong Ai, Xiaodong Li, Xudong Sun, Byung-Nam Kim, Yoshio Sakka
Hexagonal (Gd0.95RE0.05)PO4·nH2O nanowires ~300 nm in length and ~10 nm in diameter have been converted from (Gd0.95RE0.05)2(OH)5NO3·nH2O nanosheets (RE = Eu, Tb) in the presence of monoammonium phosphate (NH4H2PO4) and ethylene diamine tetraacetic acid (EDTA). They were characterized by X-ray diffraction, thermogravimetry, electron microscopy, and Fourier transform infrared and photoluminescence spectroscopies. It is shown that EDTA played an essential role in the morphology development of the nanowires...
2017: Science and Technology of Advanced Materials
https://www.readbyqxmd.com/read/28740554/concurrent-chemoradiotherapy-with-or-without-anti-egfr-targeted-treatment-for-stage-ii-ivb-nasopharyngeal-carcinoma-retrospective-analysis-with-a-large-cohort-and-long-follow-up
#19
Rui You, Yi-Jun Hua, You-Ping Liu, Qi Yang, Yi-Nuan Zhang, Ji-Bin Li, Chao-Feng Li, Xiong Zou, Tao Yu, Jing-Yu Cao, Meng-Xia Zhang, Rou Jiang, Rui Sun, Hao-Yuan Mo, Ling Guo, Ka-Jia Cao, Ai-Hua Lin, Ying Sun, Chao-Nan Qian, Jun Ma, Ming-Yuan Chen
We examined the benefits of the combination of anti-EGFR targeted treatment, cetuximab (CTX) or nimotuzumab (NTZ) and concurrent platinum-based chemoradiotherapy (CCRT) compared with CCRT alone in patients with stage II - IVb nasopharyngeal carcinoma (NPC). A total of 1,628 eligible patients with stage II - IVb NPC, who received CCRT (three cycles of 100 mg/m(2) cisplatin every 3 weeks with intensity-modulated radiotherapy) with or without CTX or NTZ between June 2009 and December 2013 were included in the analysis...
2017: Theranostics
https://www.readbyqxmd.com/read/28740545/e-selectin-targeted-sialic-acid-peg-dexamethasone-micelles-for-enhanced-anti-inflammatory-efficacy-for-acute-kidney-injury
#20
Jing-Bo Hu, Xu-Qi Kang, Jing Liang, Xiao-Juan Wang, Xiao-Ling Xu, Ping Yang, Xiao-Ying Ying, Sai-Ping Jiang, Yong-Zhong Du
The effective treatment for acute kidney injury (AKI) is currently limited, and care is primarily supportive. Sialic acid (SA) is main component of Sialyl Lewis(x) antigen on the mammalian cell surface, which participates in E-selectin binding. Therefore, dexamethasone(DXM)-loaded E-selectin-targeting sialic acid-polyethylene glycol-dexamethasone (SA-PEG-DXM/DXM) conjugate micelles are designed for ameliorating AKI. The conjugates are synthesized via the esterification reaction between PEG and SA or DXM, and can spontaneously form micelles in an aqueous solution with a 65...
2017: Theranostics
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