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https://www.readbyqxmd.com/read/28743171/a-quantified-risk-scoring-system-and-rating-model-for-postsurgical-gastroparesis-syndrome-in-gastric-cancer-patients
#1
Xiao-Dong Chen, Chen-Chen Mao, Wei-Teng Zhang, Ji Lin, Rui-Sen Wu, Feng-Min Zhang, Xiang-Wei Sun, Chu-Huai Chi, Xian Shen, Peng-Fei Wang
BACKGROUND AND OBJECTIVES: The study aimed to investigate the relationship between obesity and postsurgical gastroparesis syndrome (PGS), and to construct a scoring system and a risk model to identify patients at high risk. METHODS: A total of 634 patients were retrospectively analyzed. Clinical characteristics were evaluated via receiver operating characteristic (ROC) curve analysis. Logistic analysis was performed to determine the independent predictive indicators of PGS...
July 25, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28743043/neurotrophy-and-immunomodulation-of-induced-neural-stem-cell-grafts-in-a-mouse-model-of-closed-head-injury
#2
Mou Gao, Hui Yao, Qin Dong, Yan Zhang, Yang Yang, Yihua Zhang, Zhijun Yang, Minhui Xu, Ruxiang Xu
Closed head injury (CHI) usually results in severe and permanent neurological impairments, which are caused by several intertwined phenomena, such as cerebral edema, blood-brain barrier (BBB) disruption, neuronal loss, astroglial scarring and inflammation. We previously reported that induced neural stem cells (iNSCs), similar to neural stem cells (NSCs), can accelerate neurological recovery in vivo and produce neurotrophic factors in vitro. However, the effects of iNSC neurotrophy following CHI were not determined...
July 18, 2017: Stem Cell Research
https://www.readbyqxmd.com/read/28742805/intra-dialytic-hypertension-is-associated-with-high-mortality-in-hemodialysis-patients
#3
Chi-Young Choi, Jae Seok Park, Kyu Tae Yoon, Hyo Wook Gil, Eun Young Lee, Sae Yong Hong
BACKGROUND: Intra-dialytic hypertension (IDH) is emerging as an important issue in hemodialysis patients. Its risk factors and clinical outcomes are unclear. METHODS: A total of 73 prevalent hemodialysis patients were enrolled. They included 14 (19.2%) patients with baseline IDH and 59 patients without IDH. Their clinical parameters, laboratory parameters, and mortality were investigated over 78 months. RESULTS: The risks factor of IDH included low serum potassium levels, low ultrafiltration, and low arm muscle area...
2017: PloS One
https://www.readbyqxmd.com/read/28742730/predictive-model-for-neoplastic-potential-of-gallbladder-polyp
#4
Ju-Il Yang, Jong Kyun Lee, Dae Geon Ahn, Joo Kyung Park, Kwang Hyuck Lee, Kyu Taek Lee, Sang Ah Chi, Sin-Ho Jung
GOAL: To provide the statistical predictive model for neoplastic potential of gallbladder polyp (GBP). BACKGROUND: Many studies have attempted to define the risk factors for neoplastic potential of GBP. It remains difficult to precisely adapt the reported risk factors for the decision of surgery. Estimating the probability for neoplastic potential of GBP using a combination of several risk factors before surgical resection would be useful in patient consultation...
July 24, 2017: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/28742728/anti-n-methyl-d-aspartate-receptor-encephalitis-complicated-with-antiphospholipid-syndrome-and-cerebral-venous-thrombosis
#5
Yu-Wei Hsu, Chun-Jung Juan, Jiunn-Tay Lee, Yu-Kai Lin, Chun-Hao Lai, Fu-Chi Yang
No abstract text is available yet for this article.
August 2017: Journal of Clinical Rheumatology: Practical Reports on Rheumatic & Musculoskeletal Diseases
https://www.readbyqxmd.com/read/28742459/identification-of-clusters-that-condition-resistance-to-anthracnose-in-the-common-bean-differential-cultivars-ab136-and-mdrk
#6
Ana Campa, Noemi Trabanco, Juan Jose Ferreira
The correct identification of the anthracnose resistance systems present in the common bean cultivars AB136 and MDRK is important because both are included in the set of 12 differential cultivars proposed for use in classifying the races of the anthracnose causal agent, Colletrotrichum lindemuthianum. In this work, the responses against seven C. lindemuthianum races were analyzed in a recombinant inbred line population derived from the cross AB136 x MDRK. A genetic linkage map of 100 molecular markers distributed across the 11 bean chromosomes was developed in this population to locate the gene or genes conferring resistance against each race, based on linkage analyses and chi-square tests of independence...
July 25, 2017: Phytopathology
https://www.readbyqxmd.com/read/28742373/utility-of-mri-to-differentiate-clear-cell-renal-cell-carcinoma-adrenal-metastases-from-adrenal-adenomas
#7
Nicola Schieda, Satheesh Krishna, Matthew D F McInnes, Bardia Moosavi, Abdulmohsen Alrashed, Robert Moreland, Evan S Siegelman
OBJECTIVE: The purpose of this study is to compare MRI features of clear cell renal cell carcinoma (RCC) adrenal metastases and adenomas. MATERIALS AND METHODS: Fifteen clear cell RCC adrenal metastases imaged with MRI were compared to 29 consecutive adenomas between 2006 and 2015. Two blinded radiologists assessed homogeneity (homogeneous vs heterogeneous), signal intensity (SI) decrease on chemical-shift MRI, and T2-weighted SI (isointense, mildly hyperintense, or markedly hyperintense) relative to muscle...
July 25, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28742289/tai-chi-exercise-for-the-quality-of-life-in-a-perimenopausal-women-organization-a-systematic-review
#8
Ying Wang, Weichao Shan, Qing Li, Na Yang, Weiying Shan
BACKGROUND: Improvement of the quality of life in perimenopausal women has recently become an important global health issue. Extensive research reports provide evidence of Tai Chi for the quality of life, but no systematic review has individually investigated Tai Chi as a main intervention on the quality of life in perimenopausal women. OBJECTIVE: To assess clinical evidence of Tai Chi for the quality of life in perimenopausal women. METHODS: Studies related to the effect of Tai Chi on the quality of life in perimenopausal women in the databases of China and abroad were searched...
August 2017: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/28742195/the-use-of-susceptibility-weighted-imaging-to-detect-cerebral-microbleeds-after-lacunar-infarction
#9
L Shao, M Wang, X-H Ge, H-D Huang, L Gao, J-C Qin
OBJECTIVE: To study the value of susceptibility-weighted imaging (SWI) technology to detect cerebral microbleeds (CMBs) in senile cerebral lacunar infarction patients; and to evaluate the complicated cerebral hemorrhage risk after patients with CMBs took aspirin, an antiplatelet medication or received anticoagulant therapy. PATIENTS AND METHODS: MRI scanning, using GRE-T2*WI, SWI and FSE sequences (T1WI, T2WI, and T2FLAIR), was performed on the three groups: (1) a cerebral lacunar infarction group; (2) cerebral lacunar infarction with cerebral microbleeds (CMBs) group; and (3) a healthy elderly group...
July 2017: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/28741809/ferrocene-based-hyperbranched-polytriazoles-synthesis-by-click-polymerization-and-application-as-precursors-to-nanostructured-magnetoceramics
#10
Hongkun Li, Weiwen Chi, Yajing Liu, Wei Yuan, Yaowen Li, Yongfang Li, Ben Zhong Tang
Ferrocene-based polymers have drawn much attention in the past decades due to their unique properties and promising applications. However, the synthesis of hyperbranched polymers is still a great challenge. Here, two ferrocene-based hyperbranched polytriazoles with high molecular weights are facilely prepared by the click polymerization reactions of ferrocene-containing diazides (1) and tris(4-ethynylphenyl)amine (2) using Cu(PPh3 )3 Br as catalyst in dimethylformamide at 60 °C for 5 and 9 h in satisfactory yields of 54...
July 25, 2017: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/28741790/diallyl-trisulfide-inhibits-cell-migration-and-invasion-of-human-melanoma-a375-cells-via-inhibiting-integrin-facal-adhesion-kinase-pathway
#11
Hsiao-Chi Wang, Yung-Lin Chu, Shu-Chen Hsieh, Lee-Yan Sheen
Melanoma is the leading cause of death from skin disease due to its propensity for metastasis. Studies have shown that integrin-mediated focal adhesion kinase (FAK) signal pathway is implicated in cell proliferation, survival and metastasis of tumor cells. Our previous results indicated that diallyl trisulfide (DATS) provided its antimelanoma activity via inducing cell cycle arrest and apoptosis. The aim of this study was to explore DATS mediated antimetastatic effect and the corresponding mechanism in human melanoma A375 cells...
July 25, 2017: Environmental Toxicology
https://www.readbyqxmd.com/read/28741646/aggressiveness-in-depression-a-neglected-symptom-possibly-associated-with-bipolarity-and-mixed-features
#12
N Verdolini, G Perugi, L Samalin, A Murru, J Angst, J-M Azorin, C L Bowden, S Mosolov, A H Young, M Barbuti, G Guiso, D Popovic, E Vieta, I Pacchiarotti
OBJECTIVE: To evaluate aggressiveness during a major depressive episode (MDE) and its relationship with bipolar disorder (BD) in a post hoc analysis of the BRIDGE-II-MIX study. METHOD: A total of 2811 individuals were enrolled in this multicenter cross-sectional study. MDE patients with (MDE-A, n = 399) and without aggressiveness (MDE-N, n = 2412) were compared through chi-square test or Student's t-test. A stepwise backward logistic regression model was performed...
July 25, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/28741466/binding-of-cxcr4-transmembrane-peptides-to-the-bacterial-chaperonin-groel
#13
Xiaoqiang Wang, Haixia Chi, Shixin Li, Yan Xu
: Newly translated membrane protein CXCR4 was observed to gain significant folding enhancement upon interacting with the bacterial chaperonin GroEL-GroES. The main fold of CXCR4 consists of 7 transmembrane α-helices distinct from soluble proteins that have dominated research on the chaperonin-assisted folding. This work extends our previous observation to the binding of GroEL with CXCR4 transmembrane peptides, which are mainly composed of hydrophobic residues characteristic of the substrates recognized by the chaperonin...
July 24, 2017: Protein and Peptide Letters
https://www.readbyqxmd.com/read/28741398/effects-of-role-playing-scenarios-on-the-self-efficacy-of-students-in-resisting-against-substance-addiction-a-pilot-study
#14
Gülnaz Karatay, Nazan Gürarslan Baş
During the first phases of adolescent development, young people have little self-efficacy and resistance against substance use. The aim of this study was to demonstrate the effectiveness of role-playing scenarios on the self-efficacy of students in resisting substance use. A pre test and post test study design was used with a single group. The study was carried out with 245 secondary school students. The scenario-based training, developed by the researchers, was presented by the school counselors once a week for 4 weeks...
January 1, 2017: Inquiry: a Journal of Medical Care Organization, Provision and Financing
https://www.readbyqxmd.com/read/28741147/constipation-in-degenerative-cervico-thoracic-spine-myelopathy-a-simple-co-existence-or-a-complex-inter-relationship
#15
Anant Mehrotra, Janmejay Jamdar, Pradeep Sharma, Chaitanya Godbole, Suyash Singh, Kuntal Kanti Das, Abhai Verma, Kamlesh Singh Bhaisora, Jayesh Sardhara, Awadhesh Kumar Jaiswal, Rabi Narayan Sahu, Arun Kumar Srivastava, Sanjay Behari, Raj Kumar
PURPOSE: Identify factors affecting constipation and post surgical improvement in patients of myelopathy. METHODS: Sixty-four patients with myelopathy due to extradural spine pathologies (47 cervical; 17 thoracic spine, male:female-5.4:1 with mean age 46.16) underwent evaluation including Bristol stool scale (BSS), PFT and uroflowmetry. All cases were evaluated by gastroenterologist to rule out any intrinsic bowel disease. Chi-square test, Kruskal-Wallis/Mann-Whitney U test and Wilcoxon signed rank test were employed to ascertain statistical significance...
July 24, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28741004/seventeen-years-of-life-support-courses-for-nurses-where-are-we-now
#16
Kenneth Heng, Fong Chi Wee
The Life Support Course for Nurses (LSCN) equips nurses with the resuscitation skills to be first responders in in-hospital cardiac arrests. Seventeen years after the initiation of the LSCN, a confidential cross-sectional Qualtrics™ survey was conducted in May 2016 on LSCN graduands to assess the following: confidence in nurse-initiated resuscitation post-LSCN; defibrillation experience and outcomes; and perceived barriers and usefulness of the LSCN. The majority of respondents reported that the course was useful and enhanced their confidence in resuscitation...
July 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28740999/advanced-cardiac-life-support-2016-singapore-guidelines
#17
Chi Keong Ching, Siew Hon Benjamin Leong, Siang Jin Terrance Chua, Swee Han Lim, Kenneth Heng, Sohil Pothiawala, Venkataraman Anantharaman
The main areas of emphasis in the Advanced Cardiac Life Support (ACLS) guidelines are: early recognition of cardiac arrest and call for help; good-quality chest compressions; early defibrillation when applicable; early administration of drugs; appropriate airway management ensuring normoventilation; and delivery of appropriate post-resuscitation care to enhance survival. Of note, it is important to monitor the quality of the various care procedures. The resuscitation team needs to reduce unnecessary interruptions to chest compressions in order to maintain adequate coronary perfusion pressure during the ACLS drill...
July 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28740995/basic-cardiac-life-support-2016-singapore-guidelines
#18
Swee Han Lim, Fong Chi Wee, Tek Siong Chee
Basic Cardiac Life Support (BCLS) or cardiopulmonary resuscitation (CPR) refers to the skills required (without use of equipment) in the resuscitation of cardiac arrest individuals. On recognising cardiac arrest, chest compressions should be initiated. Good quality compressions are with arms extended, elbows locked, shoulders directly over the casualty's chest and heel of the palm on the lower half of the sternum. The rescuer pushes hard and fast, compressing 4-6 cm deep for adults at 100-120 compressions per minute with complete chest recoil...
July 2017: Singapore Medical Journal
https://www.readbyqxmd.com/read/28740814/validation-of-the-cognitively-normal-range-and-below-normal-range-subtypes-in-chronically-hospitalized-patients-with-schizophrenia
#19
Shih-Kuang Chiang, Ching-Huan Ni, Chih-Pu Tsai, Keng-Chang Lin
BACKGROUND: Many studies have found a substantial minority of patients whose performance puts them within the normal range of neuropsychological functioning. Recently, a study has seen the delineation of two neurocognitive subtypes of schizophrenia -'cognitively normal range' (CNR) and 'below normal range' (BNR) - based on neurocognitive performance across multiple domains. METHODS: The participants were from two studies that collected neurocognitive, psychopathology and social function data between 2008 and 2015...
September 2016: Schizophrenia Research. Cognition
https://www.readbyqxmd.com/read/28740482/both-low-blood-glucose-and-insufficient-treatment-confer-risk-of-neurodevelopmental-impairment-in-congenital-hyperinsulinism-a-multinational-cohort-study
#20
Annett Helleskov, Maria Melikyan, Evgenia Globa, Inna Shcherderkina, Fani Poertner, Anna-Maria Larsen, Karen Filipsen, Klaus Brusgaard, Charlotte Dahl Christiansen, Lars Kjaersgaard Hansen, Henrik T Christesen
BACKGROUND/AIMS: Congenital hyperinsulinism (CHI) is a heterogeneous disease most frequently caused by KATP-channel (ABCC8 and KCNJ11) mutations, with neonatal or later onset, variable severity, and with focal or diffuse pancreatic involvement as the two major histological types. CHI confers a high risk of neurological impairment; however, sparsely studied in larger patient series. We assessed the neurodevelopmental outcome in children with CHI at follow-up in a mixed international cohort...
2017: Frontiers in Endocrinology
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