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https://www.readbyqxmd.com/read/29353466/inter-observer-agreement-between-urologists-and-radiologists-in-interpreting-the-computed-tomography-images-of-emergency-patients-with-renal-colic
#1
Jun Young Hong, Dong Hoon Lee, In Ho Chang, Sung Bin Park, Chan Woong Kim, Byung Hoon Chi
PURPOSE: Low-dose non-enhanced computed tomography (LDCT) has been shown to provide low radiation exposure with proper diagnostic accuracy compared to standard dose non-enhanced computed tomography (SDCT) in patients with renal colic. The goal of our study is to estimate the accuracy of LDCT and SDCT interpretation by emergency medicine residents who primarily treated patients with renal colic. MATERIALS AND METHODS: Thirty sample images of both LDCT and SDCT from renal colic patients were extracted from January 2013 to December 2015 in a tertiary teaching hospital...
January 21, 2018: Urology Journal
https://www.readbyqxmd.com/read/29353447/the-combined-pn-stage-and-breast-cancer-subtypes-in-breast-cancer-a-better-discriminator-of-outcome-can-be-used-to-refine-the-8th-ajcc-staging-manual
#2
Zheng-Jun Yang, Yue Yu, Jiang-Rui Chi, Meng Guan, Ying Zhao, Xu-Chen Cao
BACKGROUND: pN stage and breast cancer subtypes (BCS) are both well-recognized prognostic indicators. Our previous work has highlighted that patients even with the same pN stage exhibited a significant survival difference in different BCS. Given this achievement, we hypothesized that a statistical interaction might exist between pN stage and BCS. The aim of this retrospective cohort study was to compare the prognostic value of the combined pN stage and BCS (pNnew stage) with either pN stage or BCS alone, and to determine if this combined new stage could serve as an alternative discriminator of outcome...
January 20, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
https://www.readbyqxmd.com/read/29353357/heath-risk-among-pesticide-sellers-in-bamenda-cameroon-and-peripheral-areas
#3
Jean Sonchieu, Edouard Nantia Akono, Cheche Tanwi Ngwamitang, Benoït Martin Ngassoum
In Bamenda and peripheral zones, studies have been focused on the effects of pesticides on farmers (pesticide users) while nothing has been done to assess the exposure of sellers to pesticides. This study aimed at evaluating the exposure of pesticide sellers in the same area. Thirty-two questionnaires were administered to 32 pesticide sellers systematically selected, and chi-square was used for statistical analysis. From each shop, a respondent was chosen among the workers according to its daily time spent in the workplace...
January 20, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29353225/spectrum-of-mutations-in-index-patients-with-familial-hypercholesterolemia-in-singapore-single-center-study
#4
Sharon Li Ting Pek, Sanjaya Dissanayake, Jessie Choi Wan Fong, Michelle Xueqin Lin, Eric Zit Liang Chan, Justin I-Shing Tang, Chee Wan Lee, Hean Yee Ong, Chee Fang Sum, Su Chi Lim, Subramaniam Tavintharan
BACKGROUND AND AIMS: Familial hypercholesterolemia (FH) is an autosomal dominant genetic disease characterized by the presence of high plasma low density lipoproteins cholesterol (LDL-c). Patients with FH, with mutation detected, are at increased risk of premature cardiovascular disease compared to those without mutations. The aim of the study was to assess the type of mutations in patients, clinically diagnosed with FH in Singapore. METHODS: Patients (probands) with untreated/highest on-treatment LDL-c>4...
December 27, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29353131/dermatoglyphic-patterns-on-fingers-and-gynecological-cancers
#5
Sakineh Abbasi, Mina Rasouli
OBJECTIVES: Fingerprints have so far been used for determining the basis of certain malignant diseases, with positive outcomes. Considering the high rates of cancer-related mortality in Iran, this study was conducted for the purpose of examining the dermatoglyphic pattern of fingers in patients with gynecological cancers as compared to healthy people. STUDY DESIGN: The present study was conducted on 151 women with gynecological cancers as the case group and 152 healthy women with no history of such cancers as control group...
November 9, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29353128/adoption-penetration-and-effectiveness-of-a-secondary-risk-screener-for-intimate-partner-violence-evidence-to-inform-screening-practices-in-integrated-care-settings
#6
Katherine M Iverson, Anneliese E Sorrentino, Scarlett L Bellamy, Alessandra R Grillo, Terri N Haywood, Elina Medvedeva, Christopher B Roberts, Melissa E Dichter
OBJECTIVE: Veterans Health Administration (VHA) has implemented screening for past-year intimate partner violence (IPV) in some healthcare facilities along with secondary screening of risk for severe violence among those screening positive in order to facilitate follow-up care for high-risk patients. We evaluated the adoption, penetration, and effectiveness of secondary screening as a tool to facilitate timely follow-up services. METHODS: Retrospective review of medical records (screening and healthcare use) of 774 women screening positive for past-year IPV (IPV+) at 11 facilities nationwide from April 2014-April 2016...
January 10, 2018: General Hospital Psychiatry
https://www.readbyqxmd.com/read/29353105/biomimetic-and-enzyme-responsive-dynamic-hydrogels-for-studying-cell-matrix-interactions-in-pancreatic-ductal-adenocarcinoma
#7
Hung-Yi Liu, Murray Korc, Chien-Chi Lin
The tumor microenvironment (TME) governs all aspects of cancer progression and in vitro 3D cell culture platforms are increasingly developed to emulate the interactions between components of the stromal tissues and cancer cells. However, conventional cell culture platforms are inadequate in recapitulating the TME, which has complex compositions and dynamically changing matrix mechanics. In this study, we developed a dynamic gelatin-hyaluronic acid hybrid hydrogel system through integrating modular thiol-norbornene photopolymerization and enzyme-triggered on-demand matrix stiffening...
January 8, 2018: Biomaterials
https://www.readbyqxmd.com/read/29353021/phosphoproteomics-unveils-stable-energy-supply-as-key-to-flooding-tolerance-in-kandelia-candel
#8
Dezhuo Pan, Lingxia Wang, Fanglin Tan, Si Lu, Xiaojie Lv, Madiha Zaynab, Chi-Lien Cheng, Yakubu Saddeeq Abubakar, Shipin Chen, Wei Chen
The mangrove Kandelia candel (L.) Druce experiences daily flooding cycles. To explore the molecular mechanism underlying the physiological adaptation of K. candel to flooding, the potential role of protein phosphorylation in flooding responses was investigated by a large-scale quantitative phosphoproteomic analysis using isobaric tag for relative and absolute quantitation. Total 2141 unique phosphopeptides and 2603 non-redundant phosphorylation sites were identified from 1516 phosphoproteins in K. candel leaves...
January 15, 2018: Journal of Proteomics
https://www.readbyqxmd.com/read/29352895/sequencing-the-oligosaccharide-pool-in-the-low-molecular-weight-heparin-dalteparin-with-offline-hplc-and-esi-ms-ms
#9
Zhangjie Wang, Tianji Zhang, Shaoshuai Xie, Xinyue Liu, Hongmei Li, Robert J Linhardt, Lianli Chi
Low molecular weight heparins (LMWHs) are widely used anticoagulant drugs. The composition and sequence of LMWH oligosaccharides determine their safety and efficacy. The short oligosaccharide pool in LMWHs undergoes more depolymerization reactions than the longer chains and is the most sensitive indicator of the manufacturing process. Electrospray ionization tandem mass spectrometry (ESI-MS/MS) has been demonstrated as a powerful tool to sequence synthetic heparin oligosaccharide but never been applied to analyze complicated mixture like LMWHs...
March 1, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29352891/efficient-gene-delivery-by-oligochitosan-conjugated-serum-albumin-facile-synthesis-polyplex-stability-and-transfection
#10
Monika Kumari, Chi-Hsien Liu, Wei-Chi Wu
Chitosan and its derivatives have shown to be potential gene carriers with biocompatiblility and safety. However, their practical delivery is far from being ideal because of the low transfection efficiency. The present work describes the potential of a natural protein, bovine serum albumin (BSA), conjugated with a natural oligosaccharide, oligochitosan (OC), as a considerable promising approach for a safe and efficient non-viral gene delivery vector. The FTIR spectra proved the effective conjugation of BSA with OC through covalent bond...
March 1, 2018: Carbohydrate Polymers
https://www.readbyqxmd.com/read/29352688/the-association-between-readmission-and-patient-experience-in-a-total-hip-arthroplasty-population
#11
(no author information available yet)
BACKGROUND: Our goal was to determine whether readmissions within 30 or 90 days following discharge are associated with Hospital Consumer Assessment of Healthcare Providers and Systems (HCAHPS) scores for total hip arthroplasty (THA) patients. METHODS: HCAHPS surveys from all patients who underwent THA between January 2016 and September 2016 in our institution were analyzed. Readmissions, demographics, baseline joint pain, joint function, and Veterans RAND-12 scores were collected...
December 29, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29352687/what-influence-does-the-time-of-year-have-on-postoperative-complications-following-total-knee-arthroplasty
#12
Nipun Sodhi, Nicolas S Piuzzi, Sarah E Dalton, Jaiben George, Mitchell Ng, Anton Khlopas, Assem A Sultan, Carlos A Higuera, Michael A Mont
BACKGROUND: The time of year might influence the occurrence of surgical complications. Therefore, this study investigated correlations between the time-of-year and 30-day postoperative complication rates following primary total knee arthroplasty (TKA). Specifically, we determined (1) postoperative complication rates across all quarters; and (2) time-of-year influence on complications using univariate and multivariate regression analyses. METHODS: CPT code 27447 identified 147,473 TKAs from the NSQIP database...
December 28, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29352593/pre-admission-proteinuria-impacts-risk-of-non-recovery-after-dialysis-requiring-acute-kidney%C3%A2-injury
#13
Benjamin J Lee, Alan S Go, Rishi Parikh, Thomas K Leong, Thida C Tan, Sophia Walia, Raymond K Hsu, Kathleen D Liu, Chi-Yuan Hsu
Renal recovery after dialysis-requiring acute kidney injury (AKI-D) is an important clinical and patient-centered outcome. Here we examined whether the pre-admission proteinuria level independently influences risk for non-recovery after AKI-D in a community-based population. All adult members of Kaiser Permanente Northern California who experienced AKI-D between January 1, 2009 and September 30, 2015 were included. Pre-admission proteinuria levels were determined by dipstick up to four years before the AKI-D hospitalization and the outcome was renal recovery (survival and dialysis-independence four weeks and more) at 90 days after initiation of renal replacement therapy...
January 9, 2018: Kidney International
https://www.readbyqxmd.com/read/29352395/association-between-crp-genetic-diversity-and-bipolar-disorder-comorbid-complications
#14
Wahid Boukouaci, José Oliveira, Bruno Etain, Meriem Bennabi, Christina Mariaselvam, Nora Hamdani, Céline Manier, Djaouida Bengoufa, Frank Bellivier, Chantal Henry, Jean-Pierre Kahn, Dominique Charron, Rajagopal Krishnamoorthy, Marion Leboyer, Ryad Tamouza
BACKGROUND: Chronic low-grade inflammation is believed to contribute, at least in a subset of patients, to the development of bipolar disorder (BD). In this context, the most investigated biological marker is the acute phase response molecule, C-reactive protein (CRP). While the genetic diversity of CRP was amply studied in various pathological settings, little is known in BD. METHODS: 568 BD patients along with 163 healthy controls (HC) were genotyped for the following single-nucleotide polymorphisms (SNPs) on the CRP gene: intron rs1417938 (+ 29) T/A, 3'-UTR rs1130864 (+ 1444) G/A, and downstream rs1205 (+ 1846) (C/T)...
January 20, 2018: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/29352337/impact-of-hepatitis-b-carrier-status-on-the-outcomes-of-surgical-treatment-of-colorectal-liver-metastases
#15
Kin Pan Au, Kenneth Siu Ho Chok, Albert Chi Yan Chan, Wing Chiu Dai, Tan To Cheung, Chung Mau Lo
BACKGROUND: Chronic hepatitis B virus (HBV) infection is associated with a lower incidence of colorectal liver metastases. We explored the impact of HBV carrier status on outcomes of surgical treatment of colorectal liver metastases. METHODS: A retrospective analysis was conducted for consecutive patients undergoing liver resection for colorectal liver metastases from 2000 to 2016. HBV carriers were matched with controls by propensity scoring. RESULTS: 304 patients with known HBV carrier status who underwent resection of colorectal liver metastases were studied...
January 19, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29352331/transanal-total-mesorectal-excision-is-it-necessary-in-the-era-of-robots
#16
Li-Jen Kuo, James Chi-Yong Ngu, Chia-Che Chen
Transanal total mesorectal excision (taTME) has been proposed to overcome the limitations of laparoscopic TME. The robotic surgical platform has already established its benefits in providing superior ergonomics, and the purported advantages of taTME may play less important a role in the era of robots.
January 19, 2018: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/29352280/leisure-time-physical-activity-and-prevalence-of-non-communicable-pathologies-and-prescription-medication-in-spain
#17
Pablo Fernandez-Navarro, María Teresa Aragones, Victoria Ley
Our aims were to describe physical activity (PA) behaviour in Spain and to examine its association with the prevalence of some of the major non-communicable diseases and with the use of prescription medication. Individualized secondary data retrieved from the 2014 European Health Interview Survey (EHIS) for Spain were used to conduct a cross-sectional epidemiological study (n = 18926). PA was assessed by two different measures: a specific designed variable for EHIS and a leisure time PA frequency-based query of the national survey...
2018: PloS One
https://www.readbyqxmd.com/read/29352249/guided-cracking-of-electrodes-by-stretching-prism-patterned-membrane-electrode-assemblies-for-high-performance-fuel-cells
#18
Chi-Yeong Ahn, Segeun Jang, Yong-Hun Cho, Jiwoo Choi, Sungjun Kim, Sang Moon Kim, Yung-Eun Sung, Mansoo Choi
Guided cracks were successfully generated in an electrode using the concentrated surface stress of a prism-patterned Nafion membrane. An electrode with guided cracks was formed by stretching the catalyst-coated Nafion membrane. The morphological features of the stretched membrane electrode assembly (MEA) were investigated with respect to variation in the prism pattern dimension (prism pitches of 20 μm and 50 μm) and applied strain (S ≈ 0.5 and 1.0). The behaviour of water on the surface of the cracked electrode was examined using environmental scanning electron microscopy...
January 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29351797/evaluating-the-impact-of-a-quality-management-intervention-on-post-abortion-contraceptive-uptake-in-private-sector-clinics-in-western-kenya-a-pre-and-post-intervention-study
#19
Susy Wendot, Rachel H Scott, Inviolata Nafula, Isaac Theuri, Edward Ikiugu, Katharine Footman
BACKGROUND: Integration of family planning counselling and method provision into safe abortion services is a key component of quality abortion care. Numerous barriers to post-abortion family planning (PAFP) uptake exist. This study aimed to evaluate the effect of a quality management intervention for providers on PAFP uptake. METHODS: We conducted a pre- and post-intervention study between November 2015 and July 2016 in nine private clinics in Western Kenya. We collected baseline and post-intervention data using in-person interviews on the day of procedure, and follow-up telephone interviews to measure contraceptive uptake in the 2 weeks following abortion...
January 19, 2018: Reproductive Health
https://www.readbyqxmd.com/read/29351774/inflammatory-bowel-disease-ibd-in-horses-a-retrospective-study-exploring-the-value-of-different-diagnostic-approaches
#20
Berit Boshuizen, Margreet Ploeg, Jeroen Dewulf, Sanne Klooster, Marco de Bruijn, Marie- Thérèse Picavet, Katrien Palmers, Lukas Plancke, Hilde De Cock, Mathijs Theelen, Catherine Delesalle
BACKGROUND: Diagnosing IBD in horses is challenging and requires a multimodal approach, since no conclusive diagnostic test is available. The objectives of this study were to provide an overview of population characteristics, results of applied diagnostic tests, treatment modalities and outcome in a large group of horses thought to have IBD and that were presented to four large equine referral hospitals, and to provide an exploratory investigation of possible associations between results of applied diagnostic tests, applied treatment modalities and outcome...
January 19, 2018: BMC Veterinary Research
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