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Bin Fu, Pei Xu, Yukuan Wang, Kun Yan, Suresh Chaudhary
Ponds are an important ecosystem in rural landscapes. They play an important role in water retention, aquatic products supply and biodiversity conservation. By using a questionnaire-based survey of rural households in a small watershed in the Three Gorges Reservoir area, we analyzed the distribution of ponds, their size and current status. The Integrated Valuation of Environmental Services and Tradeoffs (InVEST) model was used to evaluate the regulation, provision and culture services of the ponds. We found that pond density was high throughout hilly areas...
June 18, 2018: Science of the Total Environment
Juliana Bazzan Arsand, Rodrigo Barcellos Hoff, Louise Jank, Lucas N Meirelles, M Silvia Díaz-Cruz, Tânia Mara Pizzolato, Damià Barceló
Antibiotics are widely used in human medicine and veterinary production. Residues of these compounds reach the water sources through waste or direct application (e.g. aquaculture). The constant input of the parent drugs and their transformation products into the environment leads these pharmaceuticals to be considered as emerging pollutants. For some molecules, the pathway of degradation and formation in products is less known. To assess the impact of these substances in the environment and in the human health, it is necessary to elucidate the transformation products and their kinetic of degradation to evaluate the possible risks...
June 18, 2018: Science of the Total Environment
Uttariya Roy, Shubhalakshmi Sengupta, Priya Banerjee, Papita Das, Avijit Bhowal, Siddhartha Datta
This study focuses on the investigation of removal of textile dye (Reactive Yellow) by a combined approach of sorption integrated with biodegradation using low cost adsorbent fly ash immobilized with Pseudomonas sp. To ensure immobilization of bacterial species on treated fly ash, fly ash with immobilized bacterial cells was characterized using Fourier transform infrared (FTIR) spectroscopy, scanning electron microscopy (SEM), and fluorescence microscopy. Comparative batch studies were carried out using Pseudomonas sp, fly ash and immobilized Pseudomonas sp on flyash and were observed that immobilized Pseudomonas sp on flyash acted as better decolourizing agent...
June 18, 2018: Journal of Environmental Management
Ahmadreza Baghaie, Susanne Schnell, Ali Bakhshinejad, Mojtaba F Fathi, Roshan M D'Souza, Vitaliy L Rayz
Flow fields in cerebral aneurysms can be measured in vivo with phase-contrast MRI (4D Flow MRI), providing 3D anatomical magnitude images as well as 3-directional velocities through the cardiac cycle. The low spatial resolution of the 4D Flow MRI data, however, requires the images to be co-registered with higher resolution angiographic data for better segmentation of the blood vessel geometries to adequately quantify relevant flow descriptors such as wall shear stress or flow residence time. Time-of-Flight Magnetic Resonance Angiography (TOF MRA) is a non-invasive technique for visualizing blood vessels without the need to administer contrast agent...
June 15, 2018: Computers in Biology and Medicine
Sateesh Dubbu, Ashish Kumar Verma, Kadigachalam Parasuraman, Yashwant D Vankar
Synthesis of 1,2-annulated-C-aryl glycosides has been achieved in a stereoselective manner through the Diels-Alder reaction between carbohydrate-derived terminally unsubstituted dienes and in situ generated arynes. In these reactions, formation of sugar-fused (or branched) naphthalenes was also observed and found to be temperature dependent and thus constituting one of the salient features of this work. The synthetic importance of 1,2-annulated-C-aryl glycosides has been explored by transforming them into densely oxygenated products by functionalizing the unsubstituted exo-double bond...
June 6, 2018: Carbohydrate Research
Pau Comajoan, Carme Gubern, Gemma Huguet, Joaquín Serena, Elisabet Kádár, Mar Castellanos
Thrombolysis with recombinant tissue plasminogen activator (rt-PA) is the only pharmacological approved treatment for ischemic stroke, despite its associated increasing risk of hemorrhagic transformation. Since many of rt-PA effects in blood-brain barrier (BBB) are not well characterized, the study of protein changes in BBB cells after rt-PA administration may help to understand its adverse effects. Our aim was to analyze protein levels of four commonly used housekeeping proteins: β-Actin, α-Tubulin, GAPDH and HPRT in bEnd...
June 18, 2018: Journal of Proteomics
Cinzia Chiaramonte, Elettra Vestri, Flavia Tripi, Antonino Giulio Giannone, Marcello Cimador, Ferdinando Cataliotti
BACKGROUND: Female vaginoplasty reconstruction, by choice, is usually performed with adjacent tissue. However in some clinical conditions such as high urogenital confluence sinus, cloacal malformation with extreme vaginal hypoplasia, local tissue may not be available. When vaginal replacement is performed in pediatric patients intestinal segments is preferred to non-operative procedures that require continuative dilations. However mucus production, malignant transformation risk and diversion colitis are important side effects...
June 18, 2018: Journal of Pediatric and Adolescent Gynecology
Lucía Vaquero, Neus Ramos-Escobar, Clément François, Virginia Penhune, Antoni Rodríguez-Fornells
Music learning has received increasing attention in the last decades due to the variety of functions and brain plasticity effects involved during its practice. Most previous reports interpreted the differences between music experts and laymen as the result of training. However, recent investigations suggest that these differences are due to a combination of genetic predispositions with the effect of music training. Here, we tested the relationship of the dorsal auditory-motor pathway with individual behavioural differences in short-term music learning...
June 18, 2018: NeuroImage
Sarah R Horn, Madison M Long, Benjamin W Nelson, Nicholas B Allen, Philip A Fisher, Michelle L Byrne
One of the most common inflammatory markers examined in depression is C-reactive protein (CRP). However, the magnitude of the association between CRP and depression when controlling for potentially confounding factors such as age, sex, socio-economic status, body mass index, medication and other substance use, and medical illness, is unclear. Inconsistencies in other methodological practices, such as sample collection, assaying, and data cleaning and transformation, may contribute to variations in results. We aggregate studies that examined the association between CRP and depression in two ways...
June 18, 2018: Brain, Behavior, and Immunity
Francine Tavares da Silva, Kamila Furtado da Cunha, Laura Martins Fonseca, Mariana Dias Antunes, Shanise Lisie Mello El Halal, Ângela Maria Fiorentin, Elessandra da Rosa Zavareze, Alvaro Renato Guerra Dias
The ultrafine fibers were produced using a polymeric blend of soy protein isolate (SPI), polyethylene oxide (PEO), and zein at a ratio of 1:1:1 (v/v/v) by electrospinning. The ginger essential oil (GEO) was encapsulated in the ultrafine fibers and the morphology, Fourier-Transform Infrared Spectroscopy (FTIR) analysis, thermal properties and relative crystallinity were evaluated. The antimicrobial activity of ginger essential oil was evaluated against five bacteria (Listeria monocytogenes, Staphylococcus aureus, Escherichia coli 0157:H7, Salmonella typhimurium, and Pseudomonas aeruginosa)...
June 18, 2018: International Journal of Biological Macromolecules
Ningfeng Li, Feifei Wang, Qinglin Zhang, Ming Jin, Ye Lu, Shanshan Chen, Cuiju Guo, Xu Zhang
Damage and loss of retinal ganglion cells (RGCs) can cause visual impairment. The underlying molecular mechanisms that mediate RGC death in ischemic retinal diseases are still unclear. In this study, we sought to understand the neuroprotective effect of rapamycin, the selective inhibitor of mTORC1, on RGC survival and the cellular mechanics that mediate this effect. Recent studies have reported that the epidermal growth factor (EGF) receptor shows an increase in expression in astrocytes after injury, and this receptor can promote their transformation into reactive astrocytes...
June 18, 2018: Experimental Eye Research
Alaa Huwaidi, Nishit Pathak, Amir Syahir, Shinya Ikeno
Ultraviolet (UV) radiation causes damage in all living organisms, including DNA damage that leads to cell death. Herein, we provide a new technique for UV radiation protection through intracellular short peptide expression. The late embryogenesis abundant (LEA) peptide, which functions as a shield that protects macromolecules from various abiotic stress, was obtained from the Polypedilum vanderplanki group 3 LEA protein. Recombinant Escherichia coli BL21 (DE3) expressing functional LEA short peptide in vivo were exposed to UVA and UVC radiation for 4, 6, and 8 h...
June 18, 2018: Biochemical and Biophysical Research Communications
S Jiang, J Zeng, X Zhou, Y Li
Growing evidence suggests the existence of new antibiotic resistance mechanisms. Recent studies have revealed that quorum-quenching enzymes, such as MacQ, are involved in both antibiotic resistance and cell-cell communication. Furthermore, some small bacterial regulatory RNAs, classified into RNA attenuators and small RNAs, modulate the expression of resistance genes. For example, small RNA sprX, can shape bacterial resistance to glycopeptide antibiotics via specific downregulation of protein SpoVG. Moreover, some bacterial lipocalins capture antibiotics in the extracellular space, contributing to severe multidrug resistance...
June 1, 2018: Journal of Dental Research
Kristen E Brown, Troy Alan Hottle, Rubenka Bandyopadhyay, Samaneh Babaee, Rebecca Susanne Dodder, Pervin Ozge Kaplan, Carol Lenox, Dan Loughlin
The energy system is the primary source of air pollution. Thus, evolution of the energy system into the future will affect society's ability to maintain air quality. Anticipating this evolution is difficult because of inherent uncertainty in predicting future energy demand, fuel use, and technology adoption. We apply Scenario Planning to address this uncertainty, developing four very different visions of the future. Stakeholder engagement suggested technological progress and social attitudes toward the environment are critical and uncertain factors for determining future emissions...
June 21, 2018: Environmental Science & Technology
Chi Huang, Tian Xia, Junfeng Niu, Yu Yang, Sijie Lin, Xiangke Wang, Guoqing Yang, Liang Mao, Baoshan Xing
The exciting commercial application of graphene materials will increasingly lead to their release into soils, however, their potential transformation in agricultural crops and associated environmental effects are yet unknown due to difficulty in tracing the material. Our study focused on using carbon-14 labeled few-layer graphene (FLG) to determine its uptake, distribution, transformation, and depuration in rice plants. After 7 d hydroponic exposure to FLG suspension at 250 μg/L, roots accumulated 694.8 mg/kg graphene and shoots had 53...
June 21, 2018: Angewandte Chemie
Amparo Sanz-Marco, Samuel Martinez Erro, Belén Martín-Matute
The first method to access unsymmetrical aliphatic acyloins is presented. The method relies on a fast 1,3-hydride shift mediated by an Ir(III) complex in allylic alcohols followed by oxidation with TEMPO+. The direct conversion of allylic alcohols into acyloins is achieved in a one-pot procedure. Further functionalization of the Cα´ of the α-aminooxy ketone products gives access to highly functionalized unsymmetrical aliphatic ketones, which further highlights the utility of this transformation.
June 21, 2018: Chemistry: a European Journal
Adorján Cristea, Andreea Baricz, Nicolae Leopold, Călin Gabriel Floare, Gheorghe Borodi, Irina Kacso, Septimiu Tripon, Paul Adrian Bulzu, Ștefan Andrei Adrian, Oana Cadar, Erika Andrea Levei, Horia Leonard Banciu
AIM: This study aimed at unprecedented physical and chemical evaluation of the 'green plastics' polyhydroxyalkanoates (PHAs), in an extremely halotolerant Halomonas elongata strain 2FF under high salt concentration. METHODS AND RESULTS: The investigated bacterial strain was isolated from the surface water of the hypersaline Fără Fund Lake. The 16S rRNA gene sequence phylogeny and phenotypic analysis indicated that the isolate belonged to Halomonas elongata. PHA inclusions were observed by Sudan Black B, Nile Red staining and by transmission electron microscopy (TEM) during growth at high salinity (10%, w/v, NaCl) on 1% (w/v) D-glucose...
June 21, 2018: Journal of Applied Microbiology
Omid Bazgir, Seyed Amir Hassan Habibi, Lorenzo Palma, Paola Pierleoni, Saba Nafees
Background: Tremor is one of the most common symptoms of Parkinson's disease (PD), which is widely being used in the diagnosis procedure. Accurate estimation of PD tremor based on Unified PD Rating Scale (UPDRS) provides aid for physicians in prescription and home monitoring. This article presents a robust design of a classification system to estimate PD patient's hand tremors and the results of the proposed system as compared to the UPDRS. Methods: A smartphone accelerometer sensor is used for accurate and noninvasive data acquisition...
April 2018: Journal of Medical Signals and Sensors
Gagandeep Kaur, Caiyun Grace Li, Andrew Chantry, Cherie Stayner, Julia Horsfield, Michael R Eccles
Canonical TGF-β1 signalling promotes tumor progression by facilitating invasion and metastasis, whereby release of TGF-β1, by (for example) infiltrating immune cells, induces epithelial to mesenchymal transition (EMT). PAX2, a member of the Paired box family of transcriptional regulators, is normally expressed during embryonic development, including in the kidney, where it promotes mesenchymal to epithelial transition (MET). PAX2 expression is silenced in many normal adult tissues. However, in contrast, PAX2 is expressed in several cancer types, including kidney, prostate, breast, and ovarian cancer...
June 1, 2018: Oncotarget
Yuzuru Satake, Yuki Kuwano, Tatsuya Nishikawa, Kinuyo Fujita, Saki Saijo, Miki Itai, Hiroki Tanaka, Kensei Nishida, Kazuhito Rokutan
Transcribed-ultraconserved regions (T-UCRs), which contain conserved sequences with 100% identity across human, rat and mouse species, are a novel category of functional RNAs. The human transformer 2β gene ( TRA2B ) encodes a UCR that spans exon 2 (276 bp) and its neighboring introns. Among five spliced RNA variants ( TRA2β1-5 ) transcribed from the TRA2B gene, only TRA2β4 contains the conserved exon 2. TRA2β4 is overexpressed in colon cancer cells and accelerates cell growth by blocking the transcription of CDKN1A ...
June 1, 2018: Oncotarget
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