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Periprosthetic joint infection

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https://www.readbyqxmd.com/read/28639846/antibiotic-prophylaxis-is-not-indicated-prior-to-dental-procedures-for-prevention-of-periprosthetic-joint-infections
#1
Willem M H Rademacher, Geert H I M Walenkamp, Dirk Jan F Moojen, Johannes G E Hendriks, Theo A Goedendorp, Frederik R Rozema
Background and purpose - To minimize the risk of hematogenous periprosthetic joint infection (HPJI), international and Dutch guidelines recommended antibiotic prophylaxis prior to dental procedures. Unclear definitions and contradictory recommendations in these guidelines have led to unnecessary antibiotic prescriptions. To formulate new guidelines, a joint committee of the Dutch Orthopaedic and Dental Societies conducted a systematic literature review to answer the following question: can antibiotic prophylaxis be recommended for patients (with joint prostheses) undergoing dental procedures in order to prevent dental HPJI? Methods - The Medline, Embase, and Cochrane databases were searched for randomized controlled trials (RCTs), reviews, and observational studies up to July 2015...
June 22, 2017: Acta Orthopaedica
https://www.readbyqxmd.com/read/28637910/excellent-diagnostic-characteristics-for-ultra-fast-gene-profiling-of-defa1-il1b-ltf-in-the-detection-of-prosthetic-joint-infections
#2
Regina Fillerova, Jiri Gallo, Martin Radvansky, Veronika Kraiczova, Milos Kudelka, Eva Kriegova
The timely and exact diagnosis of prosthetic joint infection (PJI) is crucial for surgical decision-making. Intra-operatively, delivery of the result within an hour is required. Alpha-defensin lateral immunoassay of joint fluid (JF) is precise in the intra-operative exclusion of PJI, however in patients with a limited amount of JF and/or when the JF is bloody this test is unhelpful. Important information is hidden in the periprosthetic tissues that could much better reflect the current status of implant pathology...
June 21, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28626592/diffuse-b-cell-non-hodgkin-s-lymphoma-presenting-atypically-as-periprosthetic-joint-infection-in-a-total-hip-replacement
#3
Aysha Rajeev, Angela Ralte, Nameer Choudhry, Faizan Jabbar, Paul Banaszkiewicz
The occurrence of extranodal primary B cell non-Hodgkin's lymphoma is rare. Total hip replacement is one of the most common orthopaedic procedures performed. There has been an increased incidence of primary lymphomas involving periprosthetic sites. Chronic inflammation due to metal debris arising from the prosthetic implants has been evidenced as one of the causes for the development of soft tissue lymphomas albeit rarely. We describe a case report of a 77-year-old patient who had underwent a cemented total hip replacement in the past who further developed large B cell primary non-Hodgkin's lymphoma...
2017: Case Reports in Orthopedics
https://www.readbyqxmd.com/read/28622842/two-stage-knee-arthrodesis-with-a-modular-intramedullary-nail-due-to-septic-failure-of-revision-total-knee-arthroplasty-with-extensor-mechanism-deficiency
#4
Max J Friedrich, Jan Schmolders, Matthias D Wimmer, Andreas C Strauss, Milena M Ploeger, Dieter C Wirtz, Sascha Gravius, Thomas M Randau
BACKGROUND: Periprosthetic joint infection is a serious complication and reconstruction after failed revision total knee arthroplasty with significant bone loss and compromised soft-tissues can be challenging. Objective of this study was to assess clinical and functional results, implant survival and infection recurrence rates in patients treated with two-stage arthrodesis after failed revision TKA with extensor mechanism deficiencies due to PJI, and to identify the factors that affect outcomes after surgery...
June 13, 2017: Knee
https://www.readbyqxmd.com/read/28611966/periprostetic-joint-infection-caused-by-salmonella-case-reports-of-two-azathioprine-and-prednisolone-induced-immunocompromised-patients
#5
Mehmet Ekinci, Serkan Bayram, Turgut Akgül, Mehmet Ersin, Önder Yazicioğlu
Periprosthetic joint infection (PJI) due to Salmonella is rare. It frequently occurs patients receiving immunosuppressive medicine. We describe two periprosthetic Salmonella infection of two immunocompromised patients. Both of patients were receiving azathioprine and prednisolone therapy. First patient presented six years after total hip arthroplasty with a huge abscess on her right thigh that was reached to femoral component through the lytic area of lateral femur. Second patient presented with drainage from his hip and he had undergone two-step revision surgery for PJI 3 months ago...
June 2017: Hip & Pelvis
https://www.readbyqxmd.com/read/28610654/periprosthetic-infection-in-joint-replacement
#6
Christina Otto-Lambertz, Ayla Yagdiran, Franziska Wallscheid, Peer Eysel, Norma Jung
BACKGROUND: The volume of joint replacement surgery has risen steadily in recent years, because the population is aging and increasingly wishes to reserve a high functional status onward into old age. Infection is among the more common complications of joint replacement surgery, arising in 0.2% to 2% of patients, or as many as 9% in special situations such as the implantation of megaprostheses. The associated morbidity and mortality are high. It is thus very important to minimize risk factors for infection and to optimize the relevant diagnostic and therapeutic strategies...
May 26, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/28608224/concordance-between-the-old-and-new-diagnostic-criteria-for-periprosthetic-joint-infection
#7
Meeri Honkanen, Esa Jämsen, Matti Karppelin, Reetta Huttunen, Outi Lyytikäinen, Jaana Syrjänen
PURPOSE: There is no uniform definition for periprosthetic joint infection (PJI). New diagnostic criteria were formulated in an international consensus meeting in 2013 and adopted by Centers for Disease Control (CDC) in 2016. The purpose of this study is to compare the new diagnostic criteria with the old CDC criteria from the year 1992. METHODS: Patients, who had been treated for PJI of hip or knee from 2002 to 2014, in a tertiary care hospital, were identified...
June 12, 2017: Infection
https://www.readbyqxmd.com/read/28606121/the-risk-factors-of-failed-reimplantation-arthroplasty-for-periprosthetic-hip-infection
#8
Shun-Wun Jhan, Yu-Der Lu, Mel S Lee, Chen-Hsiang Lee, Jun-Wen Wang, Feng-Chih Kuo
BACKGROUND: Two-stage reimplantation arthroplasty is one of the standard treatments for chronic periprosthetic joint infection (PJI). Scanty data exist regarding the risk factors for failure after two-stage reimplantation for periprosthetic hip infection. The purpose of this study was to investigate and identify the risk factors associated with failure after two-stage reimplantation hip arthroplasty. METHODS: Sixty-two patients with hip PJI treated with a two-stage reimplantation protocol at our institution from 2005 to 2012 were reviewed...
June 12, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28595609/erratum-to-high-incidence-of-periprosthetic-joint-infection-with-propionibacterium-acnes-after-the-use-of-a-stemless-shoulder-prosthesis-with-metaphyseal-screw-fixation-a-retrospective-cohort-study-of-241-patients-propionibacter-infections-after-eclipse-tsa
#9
https://www.readbyqxmd.com/read/28594501/prevention-and-diagnosis-of-periprosthetic-knee-infection
#10
Bilal Mahmood, Mouhanad M El-Othmani, William M Mihalko, William A Jiranek, Wayne G Paprosky, Khaled J Saleh
Total knee arthroplasty (TKA) has become an increasingly common treatment option for patients who have debilitating knee arthritis. TKA is a relatively safe and efficient procedure that results in promising outcomes and has a positive effect on a patient's quality of life. More TKAs are being performed annually because the procedure substantially reduces pain and improves functionality; however, as the number of TKAs continues to rise, there is concern for potential complications that may result in prosthetic joint failure...
February 15, 2017: Instructional Course Lectures
https://www.readbyqxmd.com/read/28590378/increasing-body-mass-index-is-associated-with-worse-outcomes-after-shoulder-arthroplasty
#11
Eric R Wagner, Matthew T Houdek, Cathy Schleck, William S Harmsen, Joaquin Sanchez-Sotelo, Robert Cofield, John W Sperling, Bassem T Elhassan
BACKGROUND: Although obesity is associated with increased complication rates after lower-extremity arthroplasty, there is a relative paucity of studies examining the effect of body mass index (BMI) on shoulder arthroplasty. The purpose of this investigation was to evaluate the effect of BMI on implant survival and the rate of complications after shoulder arthroplasty. METHODS: Using an institutional total joint registry, 4,567 consecutive shoulder arthroplasty cases from 1970 to 2013 were studied...
June 7, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28590375/familial-clustering-identified-in-periprosthetic-joint-infection-following-primary-total-joint-arthroplasty-a-population-based-cohort-study
#12
Mike B Anderson, Karen Curtin, Jathine Wong, Christopher E Pelt, Christopher L Peters, Jeremy M Gililland
BACKGROUND: It is estimated that the cost to treat periprosthetic joint infection in the United States will approach $1.62 billion by 2020. Thus, the need to better understand the pathogenesis of periprosthetic joint infection is evident. We performed a population-based, retrospective cohort study to determine if familial clustering of periprosthetic joint infection was observed. METHODS: Analyses were conducted using software developed at the Utah Population Database (UPDB) in conjunction with the software package R...
June 7, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28587320/distribution-characteristics-of-staphylococcus-spp-in-different-phases-of-periprosthetic-joint-infection-a-review
#13
Geyong Guo, Jiaxing Wang, Yanan You, Jiaqi Tan, Hao Shen
Periprosthetic joint infection (PJI) is a devastating condition and Staphylococcus spp. are the predominant pathogens responsible, particularly coagulase-negative staphylococci (CoNS) and Staphylococcus aureus. The aim of the present systematic review was to evaluate the distribution characteristics of specific Staphylococcus spp. in different PJI phases, reveal the effect of pathogens' feature on their distribution and suggest recommendations for antibiotic treatment of Staphylococcal PJI. The present systematic review was performed using PubMed and EMBASE databases with the aim to identify existing literature that presented the spectrum of Staphylococcus spp...
June 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28585995/outcomes-of-primary-total-knee-arthroplasty-in-patients-with-hematopoietic-stem-cell-transplantation
#14
Brian P Chalmers, Cameron K Ledford, Kevin I Perry, Tad M Mabry, Arlen D Hanssen, Matthew P Abdel
Patients who have undergone hematopoietic stem cell transplantation to treat underlying bone marrow pathology represent a unique and potentially high-risk patient population for total knee arthroplasty (TKA). This study retrospectively reviewed 15 TKA procedures performed on 11 patients with a history of hematopoietic stem cell transplantation. The authors analyzed patient survivorship; clinical outcomes, including complications; and implant survivorship. Mean follow-up was 5 years (range, 2-10 years). Patient survivorship free from mortality was 91% (95% confidence interval, 76%-100%) and 55% (95% confidence interval, 25%-85%) at 2 and 5 years, respectively...
June 6, 2017: Orthopedics
https://www.readbyqxmd.com/read/28578840/acute-kidney-injury-after-first-stage-joint-revision-for-infection-risk-factors-and-the-impact-of-antibiotic-dosing
#15
Jeffrey A Geller, Gregory Cunn, Thomas Herschmiller, Taylor Murtaugh, Antonia Chen
BACKGROUND: Scarce literature exists regarding risk factors associated with postoperative acute kidney injury (AKI) after first-stage revision procedures. The purpose of this study was to determine risk factors for AKI and the efficacy of intra-articular antibiotics in infection eradication. METHODS: We retrospectively identified 247 patients who underwent a 2-stage revision procedure for the treatment of hip or knee periprosthetic joint infection. We applied previously published diagnostic criteria for AKI to determine its incidence and risk factors for its development...
May 4, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28573549/periprosthetic-joint-infection-is-the-main-cause-of-failure-for-modern-knee-arthroplasty-an-analysis-of-11-134-knees
#16
Chuan Kong Koh, Irene Zeng, Saiprassad Ravi, Mark Zhu, Kelly G Vince, Simon W Young
BACKGROUND: Although large series from national joint registries may accurately reflect indications for revision TKAs, they may lack the granularity to detect the true incidence and relative importance of such indications, especially periprosthetic joint infections (PJI). QUESTIONS/PURPOSES: Using a combination of individual chart review supplemented with New Zealand Joint Registry data, we asked: (1) What is the cumulative incidence of revision TKA? (2) What are the common indications for revising a contemporary primary TKA? (3) Do revision TKA indications differ at various followup times after primary TKA? METHODS: We identified 11,134 primary TKAs performed between 2000 and 2015 in three tertiary referral hospitals...
June 1, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28567344/predicting-lower-limb-periprosthetic-joint-infections-a-review-of-risk-factors-and-their-classification
#17
David A George, Lorenzo Drago, Sara Scarponi, Enrico Gallazzi, Fares S Haddad, Carlo L Romano
AIM: To undertook a systematic review to determine factors that increase a patient's risk of developing lower limb periprosthetic joint infections (PJI). METHODS: This systematic review included full-text studies that reviewed risk factors of developing either a hip or knee PJI following a primary arthroplasty published from January 1998 to November 2016. A variety of keywords were used to identify studies through international databases referencing hip arthroplasty, knee arthroplasty, infection, and risk factors...
May 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28566786/short-and-mid-term-results-of-revision-total-knee-arthroplasty-with-global-modular-replacement-system
#18
Dariusz Marczak, Jacek Kowalczewski, Jarosław Czubak, Tomasz Okoń, Marek Synder, Marcin Sibiński
BACKGROUND: The original knee megaprostheses with fixed or rotating hinge articulation were custom made and only used for reconstruction of the knee following distal femoral or proximal tibial tumor resections. The aim of the study was to analyze the short- and mid-term results of revision total knee arthroplasty with Global Modular Replacement System (GMRS) used in difficult situations not amenable to reconstruction with standard total knee replacement implants. MATERIALS AND METHODS: Nine patients (9 knees) were treated with this comprehensive modular implant system, with a mean age of 73...
May 2017: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/28566392/mid-term-results-of-the-biolox-delta-ceramic-on-ceramic-total-hip-arthroplasty
#19
Y K Lee, Y C Ha, J-I Yoo, W L Jo, K-C Kim, K H Koo
AIMS: We conducted a prospective study of a delta ceramic total hip arthroplasty (THA) to determine the rate of ceramic fracture, to characterise post-operative noise, and to evaluate the mid-term results and survivorship. PATIENTS AND METHODS: Between March 2009 and March 2011, 274 patients (310 hips) underwent cementless THA using a delta ceramic femoral head and liner. At each follow-up, clinical and radiological outcomes were recorded. A Kaplan-Meier analysis was undertaken to estimate survival...
June 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28558112/mid-term-results-of-total-hip-and-total-knee-arthroplasty-in-patients-with-human-immunodeficiency-virus
#20
Brian P Chalmers, Matthew P Abdel, Michael J Taunton, Robert T Trousdale, Mark W Pagnano
With antiretroviral therapy, patients who are human immunodeficiency virus (HIV)-positive are increasingly becoming candidates for total hip arthroplasty (THA) and total knee arthroplasty (TKA). Prior reports focus on perioperative complications, but longer-term outcomes remain unclear. The authors specifically analyzed clinical outcomes, perioperative complications, and survivorship free of periprosthetic joint infection (PJI) of THAs and TKAs in HIV-positive patients who had extended follow-up. A total of 21 HIV-positive patients who underwent 29 primary arthroplasties (14 THAs, 15 TKAs) from 1992 to 2012 were retrospectively reviewed...
May 30, 2017: Orthopedics
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