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https://www.readbyqxmd.com/read/28108958/biocompatibility-study-of-three-distinct-carbon-pastes-for-application-as-electrode-material-in-neural-stimulations-and-recordings
#1
Melinda Varga, Paul Wolff, Klaus-Juergen Wolter
Neural interfaces hold great promise for research and treatment of a wide variety of neurological diseases. Medical electrodes are designed to interface with the nervous system and provide control signals for neural prostheses. We fabricated previously a hook-up neural electrode. Here we investigate the in vitro cytotoxicity of three commercial carbon pastes used for printing the conductor tracks of this electrode. At first, the carbon pastes were characterized with respect to their microstructure and chemical composition...
February 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28105617/-establishment-of-prediction-model-of-acute-gastrointestinal-injury-classification-of-critically-ill-patients-based-on-digital-gastrointestinal-sounds-monitoring
#2
Yan Wang, Jianrong Wang, Weiwei Liu, Guangliang Zhang
OBJECTIVE: To develop the prediction model of acute gastrointestinal injury (AGI) classification of critically ill patients. METHODS: The binary channel gastrointestinal sounds (GIS) monitor system was used to gather and analyze the GIS of 60 consecutive critically ill patients who were admitted in Critical Care Medicine of PLA General Hospital from April 2015 to November 2015 (patients with chronic gastrointestinal disease or history of gastrointestinal surgery were excluded)...
January 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28104526/total-navigation-in-spine-surgery-a-concise-guide-to-eliminate-fluoroscopy-using-a-portable-intraoperative-ct-3d-navigation-system
#3
Rodrigo Navarro-Ramirez, Gernot Lang, Xiaofeng Lian, Connor Berlin, Insa Janssen, Ajit Jada, Marjan Alimi, Roger Härtl
BACKGROUND: Portable intraoperative computed tomography (iCT) with integrated 3D navigation offers new opportunities for more precise navigation in spinal surgery, eliminates radiation exposure for the surgical team and accelerates surgical workflows. We present the concept of "total navigation" using iCT NAV in spinal surgery. Therefore, we propose a step-by-step guideline demonstrating how total navigation can eliminate fluoroscopy with time efficient workflows integrating iCT NAV into daily practice...
January 16, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28099985/-prospective-evaluation-of-the-quality-of-the-results-of-thyroid-surgery-in-an-ent-department
#4
Peter Rolf Issing, Hendrik Tebben, Martin Wenger, Torsten Köhler
Although the thyroid gland is located in the neck it is not a matter of fact that it is a clinical issue for the otorhinolaryngologist in Germany. Probably due to historic reasons general surgeons usually perform operations on the thyroid. As at our department this kind of treatment is an established procedure we prospectively evaluated our thyroid cases in order to present our results.The prospective study started in the year of 2014. So far 231 patients were enrolled with an average age of 53,5 years (16-89)...
January 18, 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28097213/fully-automated-quantitative-cephalometry-using-convolutional-neural-networks
#5
Sercan Ö Arık, Bulat Ibragimov, Lei Xing
Quantitative cephalometry plays an essential role in clinical diagnosis, treatment, and surgery. Development of fully automated techniques for these procedures is important to enable consistently accurate computerized analyses. We study the application of deep convolutional neural networks (CNNs) for fully automated quantitative cephalometry for the first time. The proposed framework utilizes CNNs for detection of landmarks that describe the anatomy of the depicted patient and yield quantitative estimation of pathologies in the jaws and skull base regions...
January 2017: Journal of Medical Imaging
https://www.readbyqxmd.com/read/28097045/homeopathy-a-safe-much-less-expensive-non-invasive-viable-alternative-for-the-treatment-of-patients-suffering-from-loss-of-lumbar-lordosis
#6
Saiful Haque, Debarsi Das, Saugato Bhattacharya, Tathagato Sarkar, Anisur Rahman Khuda-Bukhsh
OBJECTIVES: Loss of lumbar lordosis causing pain and curvature of the vertebral skeleton to one side is a relatively uncommon disease. To our knowledge, successful treatment of loss of lumbar lordosis with any potentized homeopathic drug diluted above Avogadro's limit (that is, above a potency of 12C) has not been documented so far. In this communication, we intend to document a relatively rare case of loss of lumbar lordosis with osteophytic lippings, disc desiccation, and protrusion, causing a narrowing of secondary spinal canal and a bilateral neural foramina, leading to vertebral column curvature with acute pain in an adolescent boy...
December 2016: Journal of Pharmacopuncture
https://www.readbyqxmd.com/read/28096733/diagnosis-of-nerve-root-compromise-of-the-lumbar-spine-evaluation-of-the-performance-of-three-dimensional-isotropic-t2-weighted-turbo-spin-echo-space-sequence-at-3t
#7
Jinkyeong Sung, Won-Hee Jee, Joon-Yong Jung, Jinhee Jang, Jin-Sung Kim, Young-Hoon Kim, Kee-Yong Ha
OBJECTIVE: To explore the performance of three-dimensional (3D) isotropic T2-weighted turbo spin-echo (TSE) sampling perfection with application optimized contrasts using different flip angle evolution (SPACE) sequence on a 3T system, for the evaluation of nerve root compromise by disc herniation or stenosis from central to extraforaminal location of the lumbar spine, when used alone or in combination with conventional two-dimensional (2D) TSE sequence. MATERIALS AND METHODS: Thirty-seven patients who had undergone 3T spine MRI including 2D and 3D sequences, and had subsequent spine surgery for nerve root compromise at a total of 39 nerve levels, were analyzed...
January 2017: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/28094419/postoperative-computed-tomography-and-low-field-magnetic-resonance-imaging-findings-in-dogs-with-degenerative-lumbosacral-stenosis-treated-by-dorsal-laminectomy
#8
Martin Rapp, Charles J Ley, Kerstin Hansson, Lennart Sjöström
OBJECTIVES: To describe postoperative computed tomography (CT) and magnetic resonance imaging (MRI) findings in dogs with degenerative lumbosacral stenosis (DLSS) treated by dorsal laminectomy and partial discectomy. METHODS: Prospective clinical case study of dogs diagnosed with and treated for DLSS. Surgical and clinical findings were described. Computed tomography and low field MRI findings pre- and postoperatively were described and graded. Clinical, CT and MRI examinations were performed four to 18 months after surgery...
January 17, 2017: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/28087137/nos-interacting-protein-nosip-is-increased-in-the-colon-of-patients-with-hirschsprung-s-disease
#9
Anne-Marie O'Donnell, David Coyle, Prem Puri
PURPOSE: Voltage-dependent K(+) channels (Kv channels) participate in electrical rhythmicity and smooth muscle responses and are regulated by excitatory and inhibitory neurotransmitters. Kv channels also participate in the interstitial cell of Cajal (ICC) and smooth muscle cell (SMC) responses to neural inputs. The Kv family consists of 12 subfamilies, Kv1-Kv12, with five members of the Kv7 family identified to date: Kv7.1-Kv7.5. A recent study identified the potassium channel Kv7.5 as having a role in the excitability of ICC-IM in the mouse colon...
January 3, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/28060708/characterization-and-decoding-the-spatial-patterns-of-hand-extension-flexion-using-high-density-ecog
#10
Tianxiao Jiang, Tao Jiang, Taylor Wang, Shanshan Mei, Qingzhu Liu, Yunlin Li, Xiaofei Wang, Sujit Prabhu, Zhiyi Sha, Nuri F Ince
During awake brain surgeries, electrocorticogram (ECoG) was recorded using a high density electrode grid from the motor cortex of two subjects while they were asked to execute spontaneous hand extension and flexion. Firstly, we characterized the spatio-spectral patterns of high-density ECoG during the hand movements. In both subjects, we observed event related desynchronization (ERD) in low frequency band (LFB:8-32Hz) and event related synchronization (ERS) in high frequency band (HFB:60-200Hz) where HFB-ERS was more spatially localized and movement specific compared to LFB-ERD...
January 4, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28060689/-schwannoma-of-the-upper-extremity-retrospective-analysis-of-17-cases
#11
Ângelo Sá, Leandro Nobre Azevedo, Luísa Cunha
INTRODUCTION: Schwannoma or neurilemmoma is a benign peripheric nerve tumor that usually presents as a slow growing single lesion; it has origin in Schwann cells proliferation. Although it represents a small percentage of the benign tumors of the upper arm, it is the most frequent of neural origin. We present a retrospective study of upper limb schwannomas; our aim is establish the appropriate preoperative approach, to recognise the efficiency of the treatment and the pos-operative follow-up...
September 2016: Acta Médica Portuguesa
https://www.readbyqxmd.com/read/28057917/an-integrated-miniature-bioprocessing-for-personalized-human-induced-pluripotent-stem-cell-expansion-and-differentiation-into-neural-stem-cells
#12
Haishuang Lin, Qiang Li, Yuguo Lei
Human induced pluripotent stem cells (iPSCs) are ideal cell sources for personalized cell therapies since they can be expanded to generate large numbers of cells and differentiated into presumably all the cell types of the human body in vitro. In addition, patient specific iPSC-derived cells induce minimal or no immune response in vivo. However, with current cell culture technologies and bioprocessing, the cost for biomanufacturing clinical-grade patient specific iPSCs and their derivatives are very high and not affordable for majority of patients...
January 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28055036/preparation-and-implementation-of-optofluidic-neural-probes-for-in-vivo-wireless-pharmacology-and-optogenetics
#13
Jordan G McCall, Raza Qazi, Gunchul Shin, Shuo Li, Muhammad Hamza Ikram, Kyung-In Jang, Yuhao Liu, Ream Al-Hasani, Michael R Bruchas, Jae-Woong Jeong, John A Rogers
This Protocol Extension describes the fabrication and technical procedures for implementing ultrathin, flexible optofluidic neural probe systems that provide targeted, wireless delivery of fluids and light into the brains of awake, freely behaving animals. As a Protocol Extension article, this article describes an adaptation of an existing Protocol that offers additional applications. This protocol serves as an extension of an existing Nature Protocol describing optoelectronic devices for studying intact neural systems...
February 2017: Nature Protocols
https://www.readbyqxmd.com/read/28046940/su-f-r-03-classification-of-glioblastoma-multiforme-molecular-subtypes-using-three-dimensional-multi-modal-mr-imaging-features
#14
M Mulvey, S Muhyadeen, U Sinha
PURPOSE: Positive patient outcomes with the use of aggressive concurrent chemoradiotherapy have been shown for classical and mesenchymal glioblastoma multiformae (GBM) subtypes, while not having the same positive effect for patients with neural and proneural subtypes. Quantitative MR Imaging features from multimodal MRI have been recently explored for GBM subtype classification with some promising results. We have integrated 3D textural and moment invariant features to investigate if these will strengthen the association between glioblastoma MR image features and genomic markers...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28044343/computer-aided-detection-of-retained-surgical-needles-from-postoperative-radiographs
#15
Aunnasha Sengupta, Lubomir Hadjiiski, Heang-Ping Chan, Kenny Cha, Nikolaos Chronis, Theodore C Marentis
PURPOSE: Foreign objects, such as surgical sponges, needles, sutures, and other surgical instruments, retained in the patient's body can have dire consequences in terms of patient mortality as well as legal and financial penalties. We propose computer-aided detection (CAD) on postoperative radiographs as a potential solution to reduce the chance of retained foreign objects (RFOs) after surgery, thus alleviating one of the major concerns for patient safety in the operation room. A CAD system can function as a second pair of eyes or a prescreener for the surgeon and radiologist, depending on the CAD system design and the workflow...
January 2017: Medical Physics
https://www.readbyqxmd.com/read/28041320/image-guided-resection-of-aggressive-sacral-tumors
#16
Doniel Drazin, Neil Bhamb, Lutfi T Al-Khouja, Ari D Kappel, Terrence T Kim, J Patrick Johnson, Earl Brien
OBJECTIVE The aim of this study was to identify and discuss operative nuances utilizing image guidance in the surgical management of aggressive sacral tumors. METHODS The authors report on their single-institution, multi-surgeon, retrospective case series involving patients with pathology-proven aggressive sacral tumors treated between 2009 and 2016. They also reviewed the literature to identify articles related to aggressive sacral tumors, their diagnosis, and their surgical treatment and discuss the results together with their own experience...
January 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28038695/national-trends-in-the-surgical-management-of-adolescent-idiopathic-scoliosis-analysis-of-a-national-estimate-of-60-108-children-from-the-national-inpatient-sample-over-a-13-year-time-period-in-the-united-states
#17
Alexander A Theologis, David C Sing, Faraaz Chekeni, Mohammad Diab
STUDY DESIGN: Analysis of Nationwide Inpatient Sample (NIS). OBJECTIVE: Evaluate evolution of operative treatment of adolescent idiopathic scoliosis (AIS). SUMMARY OF BACKGROUND DATA: Spinal surgery is one of the most rapidly evolving branches of surgery. Changes in AIS operations are incompletely defined. METHODS: Children (10-18 years) with ICD-9 diagnosis of idiopathic scoliosis who underwent thoracic and/or lumbar spinal fusion identified in the NIS (1998-2011) were analyzed...
January 2017: Spine Deformity
https://www.readbyqxmd.com/read/28035477/contribution-of-intraoperative-neural-monitoring-to-preservation-of-the-external-branch-of-the-superior-laryngeal-nerve-a-randomized-prospective-clinical-trial
#18
Mehmet Uludag, Nurcihan Aygun, Kinyas Kartal, Bulent Citgez, Evren Besler, Gurkan Yetkin, Cemal Kaya, Hamdi Ozsahin, Mehmet Mihmanli, Adnan Isgor
PURPOSE: The purpose of this study was to evaluate the effect of intraoperative neuromonitoring (IONM) on the injury rate of the external branch of the superior laryngeal nerve (EBSLN) during thyroidectomy. METHODS: A total of 133 consenting patients (98 female, 35 male; mean age, 45.6 ± 11.7 years) undergoing thyroidectomy were randomly assigned to 2 groups. In group 1 (n = 65 patients, 105 nerves), superior thyroid pole dissection was performed with no attempt to identify the EBSLN; in group 2 (n = 68 patients, 106 nerves), IONM was used to identify the EBSLN during surgery...
December 29, 2016: Langenbeck's Archives of Surgery
https://www.readbyqxmd.com/read/28034892/how-i-treat-anemia-in-pregnancy-iron-cobalamin-and-folate
#19
Maureen M Achebe, Anat Gafter-Gvili
Anemia of pregnancy is considered a global health problem, affecting almost 50% of pregnant women. Anemia is an important risk factor for both fetal and maternal morbidity. The purpose of this article is to discuss diagnosis and management of the most frequent causes of anemia in pregnancy: iron, cobalamin and folate deficiencies. This paper considers three clinical cases. Iron deficiency is the most common cause. The laboratory tests that define iron deficiency, the recognition of developmental delays and cognitive abnormalities in iron-deficient neonates and the literature addressing the efficacy and safety of intravenous iron in pregnancy are reviewed...
December 29, 2016: Blood
https://www.readbyqxmd.com/read/28018557/a-hybrid-computer-aided-diagnosis-system-for-prediction-of-breast-cancer-recurrence-hpbcr-using-optimized-ensemble-learning
#20
Mohammad R Mohebian, Hamid R Marateb, Marjan Mansourian, Miguel Angel Mañanas, Fariborz Mokarian
Cancer is a collection of diseases that involves growing abnormal cells with the potential to invade or spread to the body. Breast cancer is the second leading cause of cancer death among women. A method for 5-year breast cancer recurrence prediction is presented in this manuscript. Clinicopathologic characteristics of 579 breast cancer patients (recurrence prevalence of 19.3%) were analyzed and discriminative features were selected using statistical feature selection methods. They were further refined by Particle Swarm Optimization (PSO) as the inputs of the classification system with ensemble learning (Bagged Decision Tree: BDT)...
2017: Computational and Structural Biotechnology Journal
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