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Mucormycosis

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https://www.readbyqxmd.com/read/28549519/amphotericin-impregnated-polymethylmethacrylate-beads-as-treatment-for-soft-tissue-mucormycosis
#1
Stephanie F Heller, Alberto Pochettino, Mariela Rivera, Henry J Schiller
No abstract text is available yet for this article.
May 24, 2017: Surgery
https://www.readbyqxmd.com/read/28536226/severe-medication-induced-peripheral-neuropathy-treated-with-topical-doxepin-cream-in-a-paediatric-patient-with-leukaemia
#2
Zephyr D Dworsky, Rebecca Bennett, Jenny M Kim, Dennis John Kuo
A 17-year-old female with recently relapsed acute lymphoblastic leukaemia and a treatment course complicated by rhinocerebral mucormycosis infection developed severe peripheral neuropathy during the treatment for mucormycosis infection. This was felt to be a medication side effect. Her peripheral neuropathy was refractory to many well-established treatments, but ultimately responded dramatically and consistently to a novel therapy, topical doxepin cream (5%). This case report is the first published report of the application of topical doxepin cream for treatment of peripheral neuropathy in a paediatric patient...
May 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28533866/rhinocerebral-mucormycosis-a-rare-infection
#3
Moncef Sellami, Malek Mnejja
No abstract text is available yet for this article.
2017: Pan African Medical Journal
https://www.readbyqxmd.com/read/28528060/pulmonary-mucormycosis-treated-with-lobectomy
#4
Oluwatobi Afolayan, Hannah Copeland, Salman Zaheer, Jason M Wallen
A 57 year old man was referred from an outside facility for an unresolving pneumonia. Imaging of the chest demonstrated a right lung mass with a consolidation in the middle lobe, pleural effusion, and mediastinal lymphadenopathy. Cytologic examination of cultures from the bronchoscopy and thoracentesis did not yield a definitive diagnosis. Video-assisted thoracoscopic surgery (VATS) was performed because of a retained hemothorax and a suggestive lesion. Biopsy specimens obtained during VATS were consistent with mucormycosis...
June 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28527169/isolated-renal-mucormycosis
#5
R Sriranga, Satyajeet Pawar, Wasim Khot, Neeraj Nischal, Manish Soneja, H A Venkatesh, Ragesh R Nair, Raj Kanna, Mehar C Sharma, S K Sharma
Mucormycosis in humans has been described as early as 1885 in literature. Isolated renal mucormycosis is rare as it has been mainly described in developing countries like India and China. It is rarer still to find this entity in immunocompetent young males without any risk factors. Specific guidelines on the treatment is not yet known but combined surgical and medical therapy is considered the best modality for its management. We describe a young male who presented with bilateral hydroureteronephrosis. He was initially treated as a case renal tuberculosis which is relatively more common in TB endemic country like ours...
April 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28525598/differential-diagnosis-for-pythiosis-using-thermophilic-helicase-dna-amplification-and-restriction-fragment-length-polymorphism-thda-rflp
#6
Navaporn Worasilchai, Piyasak Chaumpluk, Arunaloke Chakrabarti, Ariya Chindamporn
Pythiosis is caused by Pythium insidiosum, a fungus-like microbe belonging to the kingdom Stramenopila. Its diagnosis is challenging due to clinical and histopathological similarities with the fungal microbes that cause mucormycosis and entomophthoramycosis. In addition, the proper identification of P. insidiosum in the clinical laboratory is difficult. We have developed a rapid and accurate, species-specific identification method using a thermophilic helicase DNA amplification (tHDA) technique, to differentiate this pathogen from closely related pathogenic fungi...
May 18, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/28523894/primary-cutaneous-mucormycosis-in-an-extremely-preterm-infant-successfully-treated-with-liposomal-amphotericin-b
#7
Christopher D Lowe, Rebecca J Sainato, David R Stagliano, Maribel M Morgan, Brian P Green
Cutaneous mucormycosis is a rare but often fatal invasive fungal infection that occurs most commonly in patients with diabetes, malignancy, and other immunocompromising conditions. We report an extremely preterm (<28 weeks) baby boy who developed polymicrobial sepsis and primary cutaneous mucormycosis within his first 10 days of life. He was successfully treated with medical management alone since he was not a candidate for surgery. Successful treatment of cutaneous mucormycosis without surgical debridement has been reported on only two other occasions...
May 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28497121/implementation-of-isavuconazole-in-a-fluorescence-based-high-performance-liquid-chromatography-kit-allowing-simultaneous-detection-of-all-four-currently-licensed-mold-active-triazoles
#8
René Jørgensen, Siri Rytcher Andersen, Karen Marie Thyssen Astvad, Maiken Cavling Arendrup
Isavuconazole (ISZ) is a newly available broad-spectrum triazole agent recently approved for the treatment of both invasive aspergillosis and mucormycosis. The aim of this study was to develop a simple and reliable method for therapeutic drug monitoring (TDM) of ISZ in human plasma samples. The method involves using a kit from ChromSystems intended for TDM of itraconazole (ITZ), posaconazole (PSZ), and voriconazole (VRZ) in serum/plasma for sample preparation and high-performance liquid chromatography, using fluorescence detection with emission and excitation wavelengths set to 261 and 366 nm, respectively...
May 2017: MSphere
https://www.readbyqxmd.com/read/28480721/a-rare-cause-of-emphysematous-infectious-gastritis
#9
Jorge Galván Fernández, Maria Isabel Jiménez Cuenca, Isabel Molpeceres Martínez, María Luisa Álvarez-Quiñones
A 61 year-old man with a history of hypertension, type2 diabetes, chronic renal failure, tuberculosis and peripheral arterial disease presented with gangrene in the right leg. A right supracondylar amputation was performed, despite which the patient continued with a high fever, oliguria and hypotension (90/50). Laboratory work-up showed neutrophilic leukocytosis and metabolic acidosis. CT revealed pneumoperitoneum, emphysema and thickening of the gastric wall. Changing the CT window we can appreciate air dissecting the layers of the gastric wall...
May 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28480260/trends-in-hospitalizations-related-to-invasive-aspergillosis-and-mucormycosis-in-the-united-states-2000-2013
#10
Snigdha Vallabhaneni, Kaitlin Benedict, Gordana Derado, Rajal K Mody
BACKGROUND: Invasive aspergillosis (IA) and mucormycosis contribute to substantial mortality, especially among immunocompromised persons, including those with hematopoietic stem cell transplant (HSCT), hematologic malignancy (HM), and solid organ transplant (SOT). METHODS: Using International Classification of Diseases, Ninth Revision codes available in the National Inpatient Sample, a hospital discharge database, we estimated IA-related hospitalizations (IA-RH), mucormycosis-RH (M-RH), HSCT-RH, HM-RH, and SOT-RH during 2000-2013...
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28459080/development-of-mucormycosis-colitis-during-prolonged-hospitalization
#11
Andrew J Kruger, Rohan M Modi, Martha Yearsley, Emmanuel E Ugbarugba
No abstract text is available yet for this article.
2017: ACG Case Reports Journal
https://www.readbyqxmd.com/read/28458862/cutaneous-mucormycosis-in-an-immunocompromised-patient-a-case-report
#12
Arul E Suthananthan, Sharnice A Koek, Kishore Sieunarine
Mucormycosis is a rare and highly aggressive fungal infection, with a potential to reach its fulminant phase rapidly. We report a case of a 73-year-old immunocompromised vasculopath with cutaneous mucormycosis. The disease resulted in eventual death despite aggressive surgical debridement, revascularization of his limb and amphotericin-B. This case highlights the need to recognize this disease early as a differential of a necrotic ulcer, to prevent a potentially avoidable fatality.
March 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28458494/rhinocerebral-mucormycosis-report-of-a-rare-case
#13
Richa Sahota, Ramandeep Gambhir, Samir Anand, Avani Dixit
BACKGROUND: Mucormycosis is one of the rapidly progressing and lethal form of fungal infection which involves the nose and paranasal sinuses of the head and the neck regions. Mucormycosis also remains a threat to patients with uncontrolled diabetes or other predisposing systemic conditions. It manifests as rhinocerebral, pulmonary, gastrointestinal, cutaneous or disseminated form. The underlying conditions can influence clinical presentation and often delay diagnosis, with resultant poor outcomes...
January 2017: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/28454572/invasive-pulmonary-mucormycosis-rare-presentation-with-pulmonary-eosinophilia
#14
Taizou Hirano, Mitsuhiro Yamada, Kei Sato, Koji Murakami, Tokiwa Tamai, Yoshiya Mitsuhashi, Tsutomu Tamada, Hisatoshi Sugiura, Naomi Sato, Ryoko Saito, Junya Tominaga, Akira Watanabe, Masakazu Ichinose
BACKGROUND: Fungi can cause a variety of infectious diseases, including invasive mycosis and non-invasive mycosis, as well as allergic diseases. The different forms of mycosis usually have been described as mutually exclusive, independent entities, with few descriptions of overlapping cases. Here, we describe the first reported case of a patient with the complication of pulmonary eosinophilia in the course of invasive mucormycosis. CASE PRESENTATION: A 74-year-old Japanese man with asthma-COPD overlap underwent emergency surgery for a ruptured abdominal aortic aneurysm...
April 28, 2017: BMC Pulmonary Medicine
https://www.readbyqxmd.com/read/28450941/rapidly-progressive-rhino-orbito-cerebral-mucormycosis-in-a-patient-with-type-2-diabetes-a-case-report
#15
Yan-Xia Chen, Yin-Xi He, Hong Zhou, Mian Wang, Sheng-Ou Su
With the ongoing economic development, lifestyle changes and an aging population, diabetes mellitus has be come one of the most prevalent chronic diseases in the world. Rhino-orbito-cerebral (ROC) mucormycosis is a rare, acute and angioinvasive fungal infection that can be fatal. Mucormycosis occurs exclusively in immunocompromised patients with diabetes mellitus and other types of immunodeficiency and has three subtypes: Rhino-maxillary, rhino-orbital and ROC mucormycosis. The present study reported on a case of ROC mucormycosis in a patient with diabetic ketoacidosis...
March 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28431008/diabetes-mellitus-as-the-major-risk-factor-for-mucormycosis-in-mexico-epidemiology-diagnosis-and-outcomes-of-reported-cases
#16
Dora E Corzo-León, Luis D Chora-Hernández, Ana P Rodríguez-Zulueta, Thomas J Walsh
Mucormycosis is an emerging infectious disease with high rates of associated mortality and morbidity. Little is known about the characteristics of mucormycosis or entomophthoromycosis occurring in Mexico. A search strategy was performed of literature published in journals found in available databases and theses published online at Universidad Nacional Autónoma de México (UNAM) library website reporting clinical cases or clinical case series of mucormycosis and entomophthoromycosis occurring in Mexico between 1982 and 2016...
April 20, 2017: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/28429890/prevalence-of-the-reversed-halo-sign-in-neutropenic-patients-compared-with-non-neutropenic-patients-data-from-a-single-centre-study-involving-27-patients-with-pulmonary-mucormycosis-2003-2016
#17
Jessie Bourcier, Pierre-Marie Heudes, Florent Morio, Thomas Gastinne, Patrice Chevallier, Fanny Rialland-Battisti, Claire Garandeau, Isabelle Danner-Boucher, Patrice Le Pape, Eric Frampas, Philippe Moreau, Claire Defrance, Pierre Peterlin
Pulmonary mucormycosis (PM) is a life-threatening infection and the diagnosis can be challenging. The objective was to retrospectively explore the value of the RHS in our cohort of 27 patients with mucormycosis and its relation to neutropenia. This was a retrospective study including all patients with a diagnosis of probable or proven invasive PM according to the 2008 EORTC/MSG criteria between September 2003 to April 2016. Fisher's exact test and Mann-Whitney test, with a P-value statistically significant under ...
April 21, 2017: Mycoses
https://www.readbyqxmd.com/read/28422828/gastrointestinal-mucormycosis-of-the-jejunum-in-an-immunocompetent-patient-a-case-report
#18
Mengqing Sun, Xianming Hou, Xiaoting Wang, Ge Chen, Yupei Zhao
RATIONALE: Gastrointestinal Mucormycosis (GIM) is a kind of opportunistic fungal infection with poor prognosis. It usually occurs in patients with immune deficiency. We reported a case of immunocompetent male patient. PATIENT CONCERNS: This patient was presented as abdominal distension and gastrointestinal bleeding. DIAGNOSES: A variety of hemostatic methods was ineffective to stop the bleeding. The patient finally received laparotomy, and the jejunum lesions were found...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28420334/mucormycosis-in-renal-transplant-recipients-review-of-174-reported-cases
#19
Yan Song, Jianjun Qiao, Gaffi Giovanni, Guangjun Liu, Hao Yang, Jianyong Wu, Jianghua Chen
BACKGROUND: Mucormycosis is a highly lethal fungal infection especially in immunocompromised individuals. METHODS: In order to review the epidemiology, diagnosis, and treatment of mucormycosis in renal transplant recipients we searched publications of mucormycosis cases in renal transplant recipients in PUBMED database up to December 2015. RESULTS: A total of 174 cases in renal transplant recipients were included in this review. Most of the cases (76%) were male...
April 18, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28419686/gastrointestinal-mucormycosis-in-an-immunocompromised-host
#20
Michael Kwok, Andrew Maurice, James Carroll, Jason Brown, Carl Lisec, Leo Francis, Bhavik Patel
No abstract text is available yet for this article.
April 16, 2017: ANZ Journal of Surgery
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